Danio rerio

0 known processes

bmp2a

bone morphogenetic protein 2a

(Aliases: wu:fc59d09,bmp2)

bmp2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
skeletal system development GO:0001501 181 0.996
Human Mouse
embryonic organ morphogenesis GO:0048562 274 0.991
Zebrafish
appendage development GO:0048736 80 0.991
Zebrafish Fly
heart development GO:0007507 313 0.986
Human Zebrafish Mouse Fly
nephron epithelium morphogenesis GO:0072088 1 0.979
Mouse
liver development GO:0001889 96 0.970
Zebrafish
gland development GO:0048732 143 0.966
Zebrafish Mouse Fly
embryonic limb morphogenesis GO:0030326 2 0.945
regulation of macromolecule metabolic process GO:0060255 317 0.944
Human Zebrafish Mouse Rat Fly
response to growth factor GO:0070848 39 0.942
Human Mouse Rat
forebrain development GO:0030900 96 0.930
Human Mouse
specification of symmetry GO:0009799 204 0.926
Zebrafish
camera type eye development GO:0043010 222 0.921
embryonic organ development GO:0048568 381 0.921
Zebrafish Mouse
regulation of axon guidance GO:1902667 8 0.917
connective tissue development GO:0061448 99 0.916
Human Mouse
tube morphogenesis GO:0035239 349 0.909
Zebrafish Mouse Fly
regulation of multicellular organismal development GO:2000026 223 0.901
Human Zebrafish Mouse Rat Fly
pectoral fin development GO:0033339 50 0.901
cell morphogenesis involved in differentiation GO:0000904 195 0.888
Human Mouse
central nervous system development GO:0007417 387 0.886
Human Mouse
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.883
enzyme linked receptor protein signaling pathway GO:0007167 106 0.883
Human Zebrafish Mouse Rat Fly
cell surface receptor signaling pathway GO:0007166 325 0.881
Human Zebrafish Mouse Rat Fly
notochord development GO:0030903 54 0.878
Zebrafish
positive regulation of signaling GO:0023056 56 0.858
Human Mouse
skeletal system morphogenesis GO:0048705 102 0.853
cellular component movement GO:0006928 335 0.846
Zebrafish Mouse Fly
regulation of response to stimulus GO:0048583 269 0.844
Human Mouse
stem cell proliferation GO:0072089 4 0.843
Mouse
negative regulation of developmental process GO:0051093 65 0.843
Human Zebrafish Fly
renal tubule morphogenesis GO:0061333 1 0.835
Mouse Fly
regulation of cell differentiation GO:0045595 142 0.833
Human Zebrafish Mouse Rat Fly
heart morphogenesis GO:0003007 156 0.832
Human Zebrafish Mouse
sensory organ morphogenesis GO:0090596 200 0.832
Zebrafish Fly
regulation of metabolic process GO:0019222 359 0.831
Human Zebrafish Mouse Rat Fly
embryonic pectoral fin morphogenesis GO:0035118 24 0.830
renal system development GO:0072001 94 0.830
Zebrafish Mouse Fly
eye morphogenesis GO:0048592 144 0.830
Fly
ear development GO:0043583 127 0.825
Zebrafish Mouse
formation of primary germ layer GO:0001704 62 0.823
Zebrafish
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.820
Human
mesenchymal cell proliferation GO:0010463 1 0.815
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.811
Human
determination of bilateral symmetry GO:0009855 204 0.808
Zebrafish
regulation of anatomical structure morphogenesis GO:0022603 130 0.803
Human Zebrafish Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.802
Human Zebrafish Mouse Rat Fly
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.802
determination of heart left right asymmetry GO:0061371 117 0.799
Zebrafish
cellular biosynthetic process GO:0044249 286 0.798
Human Zebrafish Mouse Rat Fly
nephron morphogenesis GO:0072028 2 0.788
Mouse
convergent extension GO:0060026 118 0.786
Zebrafish
cartilage development GO:0051216 96 0.783
Human Mouse
digestive tract development GO:0048565 265 0.779
Zebrafish Fly
regulation of neurogenesis GO:0050767 87 0.775
Mouse Rat
hepaticobiliary system development GO:0061008 98 0.773
Zebrafish
nephron tubule morphogenesis GO:0072078 1 0.772
Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.771
Human Zebrafish Mouse Rat Fly
regulation of signaling GO:0023051 235 0.768
Human Mouse
striated muscle tissue development GO:0014706 110 0.765
Human Zebrafish Mouse
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.764
dorsal convergence GO:0060030 14 0.761
Zebrafish
regulation of biosynthetic process GO:0009889 250 0.757
Human Zebrafish Mouse Rat Fly
embryonic appendage morphogenesis GO:0035113 30 0.752
Zebrafish
optic placode formation involved in camera type eye formation GO:0046619 3 0.748
embryonic heart tube morphogenesis GO:0003143 108 0.743
Zebrafish
regulation of cellular component organization GO:0051128 86 0.741
Human Mouse
neuron projection guidance GO:0097485 86 0.741
cell growth GO:0016049 57 0.740
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.737
inner ear morphogenesis GO:0042472 63 0.734
Zebrafish
embryonic skeletal system development GO:0048706 97 0.731
ear morphogenesis GO:0042471 64 0.728
Zebrafish
regulation of growth GO:0040008 42 0.721
Fly
spinal cord anterior posterior patterning GO:0021512 1 0.720
digestive tract morphogenesis GO:0048546 231 0.716
Zebrafish Fly
regulation of cell development GO:0060284 100 0.712
Human Mouse Rat
embryonic heart tube development GO:0035050 133 0.710
Zebrafish Mouse
female sex differentiation GO:0046660 4 0.705
organic cyclic compound biosynthetic process GO:1901362 223 0.692
Human Zebrafish Mouse Rat Fly
embryonic skeletal system morphogenesis GO:0048704 93 0.690
embryonic camera type eye development GO:0031076 29 0.689
regulation of cell communication GO:0010646 232 0.685
Human Mouse
regulation of locomotion GO:0040012 55 0.685
Mouse
fin development GO:0033333 77 0.683
Zebrafish
neuron projection development GO:0031175 180 0.681
neuron development GO:0048666 262 0.678
regulation of epithelial to mesenchymal transition GO:0010717 3 0.677
Human Mouse
signal transduction GO:0007165 455 0.677
Human Zebrafish Mouse Rat Fly
appendage morphogenesis GO:0035107 56 0.673
Zebrafish Fly
regulation of primary metabolic process GO:0080090 311 0.665
Human Zebrafish Mouse Rat Fly
cell part morphogenesis GO:0032990 246 0.662
chordate embryonic development GO:0043009 271 0.661
Mouse
digestive system development GO:0055123 289 0.658
Zebrafish Fly
nucleic acid templated transcription GO:0097659 181 0.658
Human Zebrafish Mouse Rat Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.654
Human Zebrafish Mouse Rat Fly
regionalization GO:0003002 274 0.643
Zebrafish Mouse Fly
positive regulation of cellular metabolic process GO:0031325 94 0.634
Human Mouse Rat
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.633
pericardium development GO:0060039 1 0.629
Mouse
cell motility GO:0048870 244 0.623
Zebrafish Mouse Fly
blood vessel morphogenesis GO:0048514 216 0.622
regulation of nucleic acid templated transcription GO:1903506 213 0.618
Human Zebrafish Mouse Rat Fly
cell migration involved in gastrulation GO:0042074 79 0.609
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.606
Human Zebrafish Mouse Rat Fly
chemotaxis GO:0006935 104 0.603
Fly
regulation of signal transduction GO:0009966 225 0.603
Human Mouse
locomotion GO:0040011 313 0.602
Zebrafish Mouse Fly
regulation of gene expression GO:0010468 265 0.602
Human Zebrafish Mouse Rat Fly
inner ear development GO:0048839 126 0.600
Zebrafish Mouse
axonogenesis GO:0007409 152 0.599
negative regulation of multicellular organismal process GO:0051241 69 0.599
Human Zebrafish
regulation of nervous system development GO:0051960 90 0.597
Mouse Rat
negative regulation of response to stimulus GO:0048585 104 0.594
Human
heterocycle biosynthetic process GO:0018130 215 0.594
Human Zebrafish Mouse Rat Fly
regulation of developmental process GO:0050793 247 0.594
Human Zebrafish Mouse Rat Fly
regulation of axon extension involved in axon guidance GO:0048841 6 0.590
optic placode formation GO:0001743 4 0.585
negative regulation of cell communication GO:0010648 96 0.584
Human
kupffer s vesicle development GO:0070121 50 0.583
positive regulation of response to stimulus GO:0048584 80 0.571
Human Mouse
otic vesicle morphogenesis GO:0071600 34 0.570
dorsal ventral pattern formation GO:0009953 125 0.562
Zebrafish Fly
regulation of neuron projection development GO:0010975 40 0.559
single organism cell adhesion GO:0098602 29 0.554
Human
regulation of multicellular organismal process GO:0051239 277 0.551
Human Zebrafish Mouse Rat Fly
determination of left right symmetry GO:0007368 179 0.549
Zebrafish
mesodermal cell differentiation GO:0048333 21 0.546
Zebrafish
fin morphogenesis GO:0033334 53 0.540
Zebrafish
response to endogenous stimulus GO:0009719 83 0.537
Human Rat
gene expression GO:0010467 252 0.534
Human Zebrafish Mouse Rat Fly
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.528
neuron projection morphogenesis GO:0048812 161 0.526
urogenital system development GO:0001655 97 0.526
Zebrafish Mouse Fly
kidney development GO:0001822 92 0.522
Zebrafish Mouse
neuron projection extension GO:1990138 45 0.522
determination of dorsal ventral asymmetry GO:0048262 34 0.519
Zebrafish
regulation of axonogenesis GO:0050770 32 0.517
axon guidance GO:0007411 86 0.516
regulation of anterior head development GO:2000742 2 0.515
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.504
eye development GO:0001654 277 0.503
Fly
positive regulation of signal transduction GO:0009967 56 0.497
Human Mouse
hard palate development GO:0060022 4 0.491
mediolateral intercalation GO:0060031 3 0.487
cell migration GO:0016477 237 0.486
Zebrafish Mouse Fly
camera type eye morphogenesis GO:0048593 108 0.480
growth GO:0040007 174 0.479
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.479
Human Zebrafish Mouse Rat Fly
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.478
Human Zebrafish
muscle tissue development GO:0060537 110 0.478
Human Zebrafish Mouse
regulation of chemotaxis GO:0050920 18 0.478
cellular ketone metabolic process GO:0042180 11 0.475
Human
muscle cell differentiation GO:0042692 139 0.475
Human Zebrafish
odontogenesis of dentin containing tooth GO:0042475 1 0.473
Mouse
positive regulation of muscle organ development GO:0048636 1 0.473
Fly
regulation of cell migration GO:0030334 40 0.472
Mouse
negative regulation of biological process GO:0048519 304 0.469
Human Zebrafish Mouse Fly
epithelial tube morphogenesis GO:0060562 148 0.469
Zebrafish Mouse Fly
heterocycle metabolic process GO:0046483 290 0.442
Human Zebrafish Mouse Rat Fly
blood vessel development GO:0001568 246 0.442
regulation of cellular amino acid metabolic process GO:0006521 0 0.432
pectoral fin morphogenesis GO:0035138 29 0.431
embryonic neurocranium morphogenesis GO:0048702 15 0.430
ectodermal placode development GO:0071696 37 0.427
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.426
developmental cell growth GO:0048588 52 0.424
developmental growth GO:0048589 166 0.421
Fly
regulation of cell projection organization GO:0031344 44 0.420
regulation of cell proliferation GO:0042127 37 0.419
Human Zebrafish Mouse
positive regulation of macromolecule metabolic process GO:0010604 93 0.418
Human Mouse Rat
reproduction GO:0000003 40 0.416
Rat Fly
heart looping GO:0001947 94 0.416
Zebrafish
ketone biosynthetic process GO:0042181 2 0.410
Human
neuron differentiation GO:0030182 353 0.405
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.402
Human Zebrafish Mouse Rat Fly
gastrulation GO:0007369 208 0.401
Zebrafish
heart field specification GO:0003128 1 0.398
positive regulation of biological process GO:0048518 253 0.396
Human Zebrafish Mouse Rat Fly
defense response GO:0006952 47 0.395
Mouse
response to wounding GO:0009611 116 0.394
positive regulation of stem cell proliferation GO:2000648 1 0.393
localization of cell GO:0051674 244 0.392
Zebrafish Mouse Fly
regulation of cell growth GO:0001558 29 0.388
response to stress GO:0006950 263 0.378
Human Mouse
axon extension involved in axon guidance GO:0048846 10 0.378
axon extension GO:0048675 45 0.377
negative regulation of mitosis GO:0045839 3 0.372
organic hydroxy compound biosynthetic process GO:1901617 6 0.369
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.367
Human Zebrafish Mouse Rat Fly
rhombomere development GO:0021546 19 0.361
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.361
larval development GO:0002164 2 0.361
Fly
sensory organ development GO:0007423 393 0.361
Zebrafish Mouse Fly
cell projection morphogenesis GO:0048858 244 0.361
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.360
Human Zebrafish Mouse Rat Fly
transcription dna templated GO:0006351 181 0.356
Human Zebrafish Mouse Rat Fly
cell projection organization GO:0030030 284 0.356
gall bladder development GO:0061010 1 0.355
hepatocyte proliferation GO:0072574 2 0.353
branching morphogenesis of an epithelial tube GO:0048754 15 0.350
Mouse
cellular response to chemical stimulus GO:0070887 157 0.350
Human Mouse Rat Fly
negative regulation of endodermal cell fate specification GO:0042664 8 0.348
Zebrafish
single organismal cell cell adhesion GO:0016337 29 0.346
Human
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.346
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.343
Human Zebrafish Mouse Rat Fly
mesenchymal cell differentiation GO:0048762 87 0.339
Human Mouse
positive regulation of biosynthetic process GO:0009891 68 0.338
Human Mouse Rat
nitrogen compound metabolic process GO:0006807 319 0.337
Human Zebrafish Mouse Rat Fly
negative regulation of cell differentiation GO:0045596 46 0.337
Human Zebrafish Fly
embryonic cranial skeleton morphogenesis GO:0048701 90 0.337
regulation of axon extension GO:0030516 24 0.334
developmental growth involved in morphogenesis GO:0060560 86 0.331
sprouting angiogenesis GO:0002040 53 0.330
somite development GO:0061053 96 0.330
heart jogging GO:0003146 40 0.328
Zebrafish
negative regulation of endodermal cell differentiation GO:1903225 8 0.325
Zebrafish
organ formation GO:0048645 17 0.325
regulation of behavior GO:0050795 24 0.322
negative regulation of striated muscle cell differentiation GO:0051154 1 0.314
Human
mesodermal cell migration GO:0008078 12 0.313
ectodermal placode formation GO:0060788 26 0.312
brain development GO:0007420 293 0.310
Human Mouse
axon development GO:0061564 166 0.309
anterior posterior pattern specification GO:0009952 152 0.307
Mouse Fly
bmp signaling pathway GO:0030509 52 0.304
Human Zebrafish Mouse Rat Fly
positive regulation of metabolic process GO:0009893 108 0.304
Human Mouse Rat
somitogenesis GO:0001756 87 0.303
nephron development GO:0072006 31 0.298
Mouse
cell cell signaling involved in cell fate commitment GO:0045168 12 0.297
Human Zebrafish
positive regulation of cell communication GO:0010647 56 0.292
Human Mouse
rna biosynthetic process GO:0032774 181 0.291
Human Zebrafish Mouse Rat Fly
axis elongation GO:0003401 31 0.290
c21 steroid hormone biosynthetic process GO:0006700 1 0.282
Human
semicircular canal formation GO:0060876 4 0.280
Zebrafish
regulation of neuron differentiation GO:0045664 56 0.277
Mouse
regulation of cell morphogenesis GO:0022604 42 0.276
Human Mouse
rhombomere 5 development GO:0021571 4 0.275
morphogenesis of an epithelial fold GO:0060571 1 0.275
morphogenesis of a branching structure GO:0001763 21 0.273
Mouse
positive regulation of cellular process GO:0048522 201 0.271
Human Zebrafish Mouse Rat
unidimensional cell growth GO:0009826 5 0.269
phosphorylation GO:0016310 69 0.265
Human
hematopoietic or lymphoid organ development GO:0048534 191 0.262
Zebrafish Fly
cranial suture morphogenesis GO:0060363 1 0.261
endoderm development GO:0007492 49 0.260
Zebrafish
regulation of wnt signaling pathway GO:0030111 53 0.260
Human Mouse
response to bacterium GO:0009617 58 0.259
pharyngeal system development GO:0060037 18 0.259
positive regulation of nucleic acid templated transcription GO:1903508 57 0.259
Human Mouse Rat
multi organism reproductive process GO:0044703 36 0.256
Fly
nephron epithelium development GO:0072009 16 0.249
Mouse
pons development GO:0021548 11 0.243
response to chemical GO:0042221 320 0.241
Human Mouse Rat Fly
apoptotic process GO:0006915 116 0.240
Human
regulation of gastrulation GO:0010470 24 0.240
Zebrafish
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.240
Human Mouse
thrombocyte differentiation GO:0002574 4 0.239
vasculature development GO:0001944 278 0.238
pancreas development GO:0031016 84 0.237
Zebrafish
skeletal muscle organ development GO:0060538 78 0.234
convergent extension involved in gastrulation GO:0060027 71 0.232
Zebrafish
negative regulation of striated muscle tissue development GO:0045843 2 0.231
Human
nucleobase containing compound biosynthetic process GO:0034654 205 0.230
Human Zebrafish Mouse Rat Fly
pathway restricted smad protein phosphorylation GO:0060389 1 0.228
Human
negative regulation of muscle organ development GO:0048635 5 0.228
Human
spemann organizer formation GO:0060061 10 0.228
macromolecule biosynthetic process GO:0009059 227 0.228
Human Zebrafish Mouse Rat Fly
regulation of erk1 and erk2 cascade GO:0070372 4 0.226
Human
muscle organ development GO:0007517 101 0.225
Human Mouse Fly
otic placode formation GO:0043049 23 0.225
regulation of localization GO:0032879 104 0.224
Mouse
endocrine system development GO:0035270 65 0.224
Mouse
insulin like growth factor receptor signaling pathway GO:0048009 4 0.223
Human
taxis GO:0042330 109 0.223
Fly
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.220
Human Zebrafish
negative regulation of cell fate commitment GO:0010454 13 0.219
Zebrafish
immune system process GO:0002376 241 0.218
Zebrafish Fly
negative regulation of axon guidance GO:1902668 1 0.217
developmental induction GO:0031128 10 0.217
Human
cellular response to growth factor stimulus GO:0071363 39 0.216
Human Mouse Rat
cellular macromolecule metabolic process GO:0044260 391 0.214
Human Zebrafish Mouse Rat Fly
rna metabolic process GO:0016070 219 0.213
Human Zebrafish Mouse Rat Fly
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.208
negative regulation of cellular process GO:0048523 283 0.208
Human Zebrafish Mouse Fly
response to external stimulus GO:0009605 264 0.207
Rat Fly
nucleobase containing compound metabolic process GO:0006139 274 0.207
Human Zebrafish Mouse Rat Fly
positive regulation of gene expression GO:0010628 71 0.207
Human Mouse Rat
neuron fate specification GO:0048665 20 0.206
regulation of mesenchymal cell proliferation GO:0010464 1 0.203
convergent extension involved in axis elongation GO:0060028 26 0.202
angiogenesis GO:0001525 158 0.201
negative regulation of muscle tissue development GO:1901862 2 0.201
Human
organic substance biosynthetic process GO:1901576 289 0.200
Human Zebrafish Mouse Rat Fly
retina morphogenesis in camera type eye GO:0060042 79 0.199
neural nucleus development GO:0048857 15 0.199
regulation of response to external stimulus GO:0032101 31 0.199
hepatic duct development GO:0061011 2 0.198
regulation of endodermal cell fate specification GO:0042663 15 0.196
Zebrafish
retina development in camera type eye GO:0060041 146 0.196
cell migration involved in heart development GO:0060973 22 0.196
reproductive process GO:0022414 40 0.195
Rat Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.195
Human Zebrafish Mouse Rat Fly
embryonic pattern specification GO:0009880 44 0.191
Fly
regulation of cell size GO:0008361 29 0.190
cellular response to estrogen stimulus GO:0071391 24 0.190
negative regulation of cell development GO:0010721 26 0.188
pronephros development GO:0048793 69 0.187
Zebrafish
regulation of embryonic development GO:0045995 47 0.187
Zebrafish
regulation of cellular protein metabolic process GO:0032268 52 0.186
Human
rhombomere 6 development GO:0021572 4 0.186
cellular response to organic substance GO:0071310 105 0.185
Human Mouse Rat
regulation of stem cell differentiation GO:2000736 4 0.183
Human Mouse
cell fate commitment GO:0045165 99 0.183
Human Zebrafish Mouse Fly
negative regulation of signaling GO:0023057 96 0.183
Human
mesoderm morphogenesis GO:0048332 51 0.182
Zebrafish
cellular response to endogenous stimulus GO:0071495 68 0.179
Human Rat
alcohol biosynthetic process GO:0046165 2 0.178
Human
regulation of cellular amine metabolic process GO:0033238 0 0.177
specification of organ identity GO:0010092 2 0.177
intracellular signal transduction GO:0035556 85 0.176
Human
oxoacid metabolic process GO:0043436 31 0.176
cellular protein metabolic process GO:0044267 129 0.174
Human
cellular component morphogenesis GO:0032989 336 0.173
Human Mouse Fly
female gamete generation GO:0007292 14 0.171
Fly
habenula development GO:0021986 9 0.171
kidney epithelium development GO:0072073 23 0.170
Mouse
positive regulation of intracellular signal transduction GO:1902533 15 0.170
Human
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.169
bone development GO:0060348 14 0.167
Human
single organism reproductive process GO:0044702 40 0.166
Rat Fly
cognition GO:0050890 1 0.165
regulation of cellular response to growth factor stimulus GO:0090287 35 0.165
regulation of macromolecule biosynthetic process GO:0010556 225 0.165
Human Zebrafish Mouse Rat Fly
mesoderm formation GO:0001707 43 0.163
Zebrafish
positive regulation of rna metabolic process GO:0051254 59 0.161
Human Mouse Rat
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.160
amine metabolic process GO:0009308 2 0.159
regulation of wnt signaling pathway involved in heart development GO:0003307 2 0.155
Human
regulation of cellular metabolic process GO:0031323 320 0.154
Human Zebrafish Mouse Rat Fly
cellular protein modification process GO:0006464 100 0.152
Human
otic vesicle formation GO:0030916 27 0.151
regulation of bmp signaling pathway GO:0030510 39 0.151
embryonic camera type eye formation GO:0060900 10 0.150
cortisol biosynthetic process GO:0034651 1 0.150
Human
cellular amino acid metabolic process GO:0006520 7 0.150
regulation of transcription involved in cell fate commitment GO:0060850 1 0.149
Human Zebrafish
regulation of biological quality GO:0065008 263 0.149
Human Mouse Fly
regulation of biomineral tissue development GO:0070167 2 0.149
Human
positive regulation of transcription dna templated GO:0045893 57 0.148
Human Mouse Rat
positive regulation of rna biosynthetic process GO:1902680 57 0.147
Human Mouse Rat
head development GO:0060322 303 0.146
Human Mouse
negative regulation of signal transduction GO:0009968 94 0.146
Human
determination of dorsal identity GO:0048263 13 0.146
regeneration GO:0031099 91 0.145
morphogenesis of an epithelium GO:0002009 333 0.144
Zebrafish Mouse Fly
regulation of rna biosynthetic process GO:2001141 213 0.143
Human Zebrafish Mouse Rat Fly
development of primary female sexual characteristics GO:0046545 4 0.143
kidney morphogenesis GO:0060993 15 0.141
Mouse
positive regulation of cellular component movement GO:0051272 11 0.141
Mouse
regulation of cellular component movement GO:0051270 55 0.140
Mouse
positive regulation of multicellular organismal process GO:0051240 52 0.140
Human Mouse Rat Fly
pericardium morphogenesis GO:0003344 1 0.139
regulation of chondrocyte differentiation GO:0032330 1 0.139
multi organism process GO:0051704 134 0.138
Fly
bone mineralization GO:0030282 9 0.136
Human Mouse
negative regulation of cardiac muscle cell differentiation GO:2000726 1 0.135
Human
neural tube development GO:0021915 62 0.134
segmentation GO:0035282 97 0.134
fin regeneration GO:0031101 51 0.134
mesenchyme development GO:0060485 127 0.133
Human Zebrafish Mouse
carboxylic acid metabolic process GO:0019752 22 0.131
regulation of stem cell proliferation GO:0072091 2 0.129
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.129
ventricular cardiac muscle cell development GO:0055015 5 0.129
Zebrafish
response to organic cyclic compound GO:0014070 51 0.128
Mouse
positive regulation of cell migration GO:0030335 11 0.128
Mouse
positive regulation of map kinase activity GO:0043406 3 0.125
Human
epidermis development GO:0008544 48 0.125
embryonic eye morphogenesis GO:0048048 30 0.123
regulation of cell cycle GO:0051726 52 0.122
Human
craniofacial suture morphogenesis GO:0097094 2 0.122
biosynthetic process GO:0009058 294 0.121
Human Zebrafish Mouse Rat Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.121
cortisol metabolic process GO:0034650 2 0.120
Human
regulation of multicellular organism growth GO:0040014 4 0.120
regulation of reproductive process GO:2000241 4 0.119
protein metabolic process GO:0019538 183 0.118
Human Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.118
Mouse Fly
defense response to other organism GO:0098542 33 0.116
gastrulation with mouth forming second GO:0001702 44 0.115
positive regulation of molecular function GO:0044093 33 0.115
Human
regulation of molecular function GO:0065009 70 0.114
Human
multicellular organism growth GO:0035264 4 0.113
motor neuron axon guidance GO:0008045 23 0.113
peptidyl serine modification GO:0018209 2 0.112
locus ceruleus development GO:0021703 3 0.110
hindbrain development GO:0030902 91 0.110
lateral line development GO:0048882 66 0.110
cartilage condensation GO:0001502 3 0.109
embryonic viscerocranium morphogenesis GO:0048703 52 0.109
embryonic camera type eye morphogenesis GO:0048596 19 0.109
response to organic substance GO:0010033 153 0.108
Human Mouse Rat
negative chemotaxis GO:0050919 1 0.107
protein modification process GO:0036211 100 0.107
Human
regulation of cellular ketone metabolic process GO:0010565 7 0.105
Human
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.103
positive regulation of nervous system development GO:0051962 25 0.102
Mouse Rat
germ line stem cell division GO:0042078 1 0.102
Fly
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.102
regulation of inflammatory response GO:0050727 2 0.102
endoderm formation GO:0001706 29 0.102
Zebrafish
positive regulation of muscle tissue development GO:1901863 1 0.102
post anal tail morphogenesis GO:0036342 19 0.100
regulation of developmental growth GO:0048638 38 0.099
Fly
tissue regeneration GO:0042246 74 0.099
p38mapk cascade GO:0038066 1 0.097
Human
protein localization to nucleus GO:0034504 3 0.097
mesoderm development GO:0007498 88 0.096
Zebrafish Fly
negative regulation of gastrulation GO:2000542 11 0.095
Zebrafish
cell migration to the midline involved in heart development GO:0003318 12 0.093
bmp signaling pathway involved in heart development GO:0061312 15 0.093
Human Zebrafish
regulation of insulin like growth factor receptor signaling pathway GO:0043567 1 0.092
Human
regulation of bone mineralization GO:0030500 2 0.092
Human
cardiac atrium morphogenesis GO:0003209 2 0.091
response to external biotic stimulus GO:0043207 97 0.090
otolith development GO:0048840 32 0.090
endocrine pancreas development GO:0031018 27 0.090
organic acid metabolic process GO:0006082 31 0.090
negative regulation of muscle cell differentiation GO:0051148 1 0.090
Human
dorsal ventral axis specification GO:0009950 14 0.090
Zebrafish Fly
positive regulation of epithelial cell differentiation GO:0030858 2 0.090
anterior posterior axon guidance GO:0033564 5 0.089
limb bud formation GO:0060174 2 0.089
organic cyclic compound metabolic process GO:1901360 301 0.089
Human Zebrafish Mouse Rat Fly
cell fate specification GO:0001708 68 0.089
Zebrafish Fly
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.089
Zebrafish
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.088
Zebrafish
skin development GO:0043588 54 0.086
cellular response to hormone stimulus GO:0032870 39 0.086
hormone biosynthetic process GO:0042446 3 0.085
Human
metencephalon development GO:0022037 27 0.085
regulation of protein modification process GO:0031399 29 0.085
Human
tissue remodeling GO:0048771 4 0.085
positive regulation of wnt signaling pathway GO:0030177 13 0.085
Mouse
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.084
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.084
cellular response to organic cyclic compound GO:0071407 38 0.084
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.084
Human Mouse Rat
negative regulation of nuclear division GO:0051784 3 0.083
protein targeting to nucleus GO:0044744 3 0.083
negative regulation of macromolecule metabolic process GO:0010605 76 0.083
Human Mouse Fly
regulation of endodermal cell differentiation GO:1903224 15 0.082
Zebrafish
developmental process involved in reproduction GO:0003006 27 0.082
Fly
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.082
inositol lipid mediated signaling GO:0048017 2 0.082
nucleocytoplasmic transport GO:0006913 4 0.082
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.082
Human
negative regulation of wnt signaling pathway GO:0030178 30 0.082
Human
mesodermal cell fate commitment GO:0001710 14 0.081
Zebrafish
skeletal muscle tissue development GO:0007519 67 0.081
inner ear receptor cell fate commitment GO:0060120 4 0.081
spinal cord patterning GO:0021511 6 0.080
negative regulation of cell proliferation GO:0008285 8 0.079
Human Mouse
negative regulation of cellular metabolic process GO:0031324 77 0.079
Human Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.079
Human Zebrafish Mouse Rat Fly
biological adhesion GO:0022610 40 0.079
Human
liver morphogenesis GO:0072576 8 0.079
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.079
single organism nuclear import GO:1902593 3 0.079
embryonic skeletal joint development GO:0072498 3 0.078
negative regulation of cell death GO:0060548 60 0.077
positive regulation of cellular protein metabolic process GO:0032270 22 0.077
Human
endothelial cell migration GO:0043542 19 0.077
cell proliferation GO:0008283 80 0.076
Human Zebrafish Mouse
positive regulation of programmed cell death GO:0043068 29 0.075
Human
regulation of organ morphogenesis GO:2000027 35 0.075
Human Mouse
bmp signaling pathway involved in heart jogging GO:0003303 14 0.075
Zebrafish
cell cycle GO:0007049 93 0.075
Human
auditory receptor cell fate commitment GO:0009912 4 0.074
adenohypophysis development GO:0021984 15 0.074
Mouse
morphogenesis of a branching epithelium GO:0061138 16 0.074
Mouse
regulation of intracellular signal transduction GO:1902531 57 0.074
Human
response to fibroblast growth factor GO:0071774 22 0.073
protein import GO:0017038 3 0.073
embryonic skeletal joint morphogenesis GO:0060272 3 0.073
homeostatic process GO:0042592 142 0.073
artery morphogenesis GO:0048844 14 0.072
regulation of binding GO:0051098 3 0.072
positive regulation of cell motility GO:2000147 11 0.071
Mouse
limb development GO:0060173 8 0.071
regulation of tissue remodeling GO:0034103 2 0.071
multicellular organism reproduction GO:0032504 35 0.071
Rat Fly
anal fin morphogenesis GO:0035144 1 0.070
Zebrafish

bmp2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.230
Human
bone development disease DOID:0080006 0 0.222
Human
bone disease DOID:0080001 0 0.222
Human
musculoskeletal system disease DOID:17 0 0.222
Human
connective tissue disease DOID:65 0 0.222
Human