|
|
bmp signaling pathway involved in heart development
|
GO:0061312 |
15 |
1.000
|
Human Zebrafish |
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
1 |
1.000
|
Human |
|
|
germ line stem cell division
|
GO:0042078 |
1 |
1.000
|
Fly |
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.999
|
|
|
|
heart field specification
|
GO:0003128 |
1 |
0.999
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
200 |
0.999
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
1 |
0.999
|
Human |
|
|
skeletal system development
|
GO:0001501 |
181 |
0.999
|
Human Mouse |
|
|
heart development
|
GO:0007507 |
313 |
0.999
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
1 |
0.999
|
Mouse |
|
|
medial fin development
|
GO:0033338 |
16 |
0.999
|
Zebrafish |
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.999
|
|
|
|
determination of ventral identity
|
GO:0048264 |
21 |
0.999
|
|
|
|
inner ear development
|
GO:0048839 |
126 |
0.998
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
2 |
0.998
|
Human |
|
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.998
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.998
|
|
|
|
medial fin morphogenesis
|
GO:0035141 |
14 |
0.997
|
Zebrafish |
|
|
ventricular cardiac muscle cell differentiation
|
GO:0055012 |
6 |
0.997
|
|
|
|
otic vesicle morphogenesis
|
GO:0071600 |
34 |
0.996
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
3 |
0.996
|
Human |
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.995
|
|
|
|
appendage development
|
GO:0048736 |
80 |
0.994
|
Zebrafish Fly |
|
|
central nervous system development
|
GO:0007417 |
387 |
0.994
|
Human Mouse |
|
|
negative regulation of gastrulation
|
GO:2000542 |
11 |
0.994
|
|
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.994
|
|
|
|
regulation of bmp signaling pathway involved in heart jogging
|
GO:2000223 |
12 |
0.994
|
|
|
|
heart jogging
|
GO:0003146 |
40 |
0.994
|
Zebrafish |
|
|
regulation of transcription from rna polymerase ii promoter involved in heart development
|
GO:1901213 |
15 |
0.994
|
Human Zebrafish |
|
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.994
|
|
|
|
regulation of endodermal cell fate specification
|
GO:0042663 |
15 |
0.994
|
|
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.993
|
|
|
|
immune system process
|
GO:0002376 |
241 |
0.993
|
Zebrafish Fly |
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.993
|
|
|
|
steroid hormone mediated signaling pathway
|
GO:0043401 |
9 |
0.993
|
|
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.992
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
52 |
0.992
|
|
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.992
|
|
|
|
bmp signaling pathway involved in determination of left right symmetry
|
GO:0003154 |
14 |
0.992
|
Zebrafish |
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
76 |
0.991
|
Human Mouse Fly |
|
|
hemopoiesis
|
GO:0030097 |
183 |
0.990
|
Zebrafish Fly |
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.989
|
|
|
|
negative regulation of muscle cell differentiation
|
GO:0051148 |
1 |
0.988
|
Human |
|
|
mesenchyme development
|
GO:0060485 |
127 |
0.988
|
Human Zebrafish Mouse |
|
|
signal transduction
|
GO:0007165 |
455 |
0.986
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
63 |
0.986
|
|
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.986
|
Human Mouse |
|
|
gastrulation
|
GO:0007369 |
208 |
0.985
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
1 |
0.985
|
Human |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
50 |
0.984
|
Human |
|
|
mesoderm morphogenesis
|
GO:0048332 |
51 |
0.984
|
|
|
|
regionalization
|
GO:0003002 |
274 |
0.984
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.983
|
|
|
|
semicircular canal morphogenesis
|
GO:0048752 |
18 |
0.983
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
2 |
0.982
|
Human |
|
|
sensory organ development
|
GO:0007423 |
393 |
0.981
|
|
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.981
|
|
|
|
regulation of transcription involved in cell fate commitment
|
GO:0060850 |
1 |
0.978
|
Human Zebrafish |
|
|
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry
|
GO:1900094 |
17 |
0.978
|
Zebrafish |
|
|
head development
|
GO:0060322 |
303 |
0.976
|
Human Mouse |
|
|
proepicardium development
|
GO:0003342 |
4 |
0.976
|
Zebrafish |
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
57 |
0.976
|
Human Mouse Rat |
|
|
limb development
|
GO:0060173 |
8 |
0.975
|
|
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.974
|
|
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.974
|
|
|
|
cranial suture morphogenesis
|
GO:0060363 |
1 |
0.973
|
|
|
|
bmp signaling pathway involved in heart jogging
|
GO:0003303 |
14 |
0.973
|
Zebrafish |
|
|
embryonic camera type eye development
|
GO:0031076 |
29 |
0.971
|
|
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.971
|
Human Mouse |
|
|
eye morphogenesis
|
GO:0048592 |
144 |
0.970
|
Fly |
|
|
specification of symmetry
|
GO:0009799 |
204 |
0.969
|
|
|
|
negative regulation of endodermal cell fate specification
|
GO:0042664 |
8 |
0.969
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
38 |
0.969
|
Mouse Fly |
|
|
ear development
|
GO:0043583 |
127 |
0.968
|
|
|
|
specification of organ position
|
GO:0010159 |
3 |
0.967
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
69 |
0.967
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
55 |
0.967
|
|
|
|
cell surface receptor signaling pathway involved in heart development
|
GO:0061311 |
20 |
0.967
|
Human Zebrafish |
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.967
|
|
|
|
positive regulation of muscle organ development
|
GO:0048636 |
1 |
0.967
|
Fly |
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.966
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
148 |
0.966
|
Zebrafish Mouse Fly |
|
|
regulation of cell proliferation
|
GO:0042127 |
37 |
0.966
|
Human Zebrafish Mouse |
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.966
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
110 |
0.965
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
2 |
0.964
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
2 |
0.963
|
|
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.963
|
|
|
|
glomerulus vasculature development
|
GO:0072012 |
2 |
0.963
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
216 |
0.962
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
80 |
0.961
|
|
|
|
mesoderm development
|
GO:0007498 |
88 |
0.961
|
|
|
|
fin morphogenesis
|
GO:0033334 |
53 |
0.961
|
Zebrafish |
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
114 |
0.961
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
125 |
0.961
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
39 |
0.961
|
|
|
|
semicircular canal formation
|
GO:0060876 |
4 |
0.959
|
|
|
|
negative regulation of striated muscle tissue development
|
GO:0045843 |
2 |
0.958
|
Human |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
3 |
0.957
|
|
|
|
regulation of endodermal cell differentiation
|
GO:1903224 |
15 |
0.957
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
17 |
0.956
|
Human |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.956
|
|
|
|
ossification
|
GO:0001503 |
23 |
0.955
|
Human Mouse |
|
|
regulation of cardiac muscle cell differentiation
|
GO:2000725 |
1 |
0.955
|
Human |
|
|
otic placode formation
|
GO:0043049 |
23 |
0.952
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
56 |
0.952
|
Human Mouse |
|
|
negative regulation of muscle tissue development
|
GO:1901862 |
2 |
0.952
|
Human |
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.951
|
|
|
|
c21 steroid hormone biosynthetic process
|
GO:0006700 |
1 |
0.950
|
Human |
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
13 |
0.950
|
|
|
|
glucocorticoid metabolic process
|
GO:0008211 |
2 |
0.950
|
Human |
|
|
immune system development
|
GO:0002520 |
191 |
0.948
|
Zebrafish Fly |
|
|
osteoblast differentiation
|
GO:0001649 |
5 |
0.948
|
Human Mouse |
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.948
|
Human Zebrafish Mouse Rat Fly |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
22 |
0.948
|
|
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.948
|
|
|
|
otic vesicle formation
|
GO:0030916 |
27 |
0.947
|
|
|
|
morphogenesis of an epithelial fold
|
GO:0060571 |
1 |
0.946
|
|
|
|
endoderm formation
|
GO:0001706 |
29 |
0.946
|
|
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.946
|
|
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.945
|
Human Mouse |
|
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.945
|
|
|
|
renal system vasculature development
|
GO:0061437 |
2 |
0.942
|
|
|
|
liver development
|
GO:0001889 |
96 |
0.942
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
4 |
0.942
|
Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
68 |
0.942
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
38 |
0.941
|
Mouse |
|
|
retina development in camera type eye
|
GO:0060041 |
146 |
0.941
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.940
|
Human Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
3 |
0.939
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
29 |
0.939
|
Human |
|
|
endodermal cell differentiation
|
GO:0035987 |
19 |
0.937
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
62 |
0.937
|
|
|
|
kidney vasculature development
|
GO:0061440 |
2 |
0.935
|
|
|
|
mesenchyme morphogenesis
|
GO:0072132 |
5 |
0.935
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
39 |
0.933
|
|
|
|
glial cell differentiation
|
GO:0010001 |
42 |
0.932
|
Mouse |
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.928
|
|
|
|
cellular response to organic substance
|
GO:0071310 |
105 |
0.928
|
Human Mouse Rat |
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
30 |
0.927
|
Zebrafish |
|
|
regulation of cellular macromolecule biosynthetic process
|
GO:2000112 |
222 |
0.922
|
|
|
|
hindbrain development
|
GO:0030902 |
91 |
0.918
|
|
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.918
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
51 |
0.917
|
Mouse |
|
|
camera type eye development
|
GO:0043010 |
222 |
0.917
|
|
|
|
death
|
GO:0016265 |
121 |
0.915
|
Human |
|
|
response to stress
|
GO:0006950 |
263 |
0.913
|
Human Mouse |
|
|
striated muscle cell differentiation
|
GO:0051146 |
129 |
0.912
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
34 |
0.911
|
|
|
|
ear morphogenesis
|
GO:0042471 |
64 |
0.911
|
|
|
|
digestive tract development
|
GO:0048565 |
265 |
0.910
|
|
|
|
anal fin morphogenesis
|
GO:0035144 |
1 |
0.909
|
Zebrafish |
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.909
|
|
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.908
|
|
|
|
fin development
|
GO:0033333 |
77 |
0.907
|
Zebrafish |
|
|
negative regulation of signaling
|
GO:0023057 |
96 |
0.907
|
Human |
|
|
nephron tubule morphogenesis
|
GO:0072078 |
1 |
0.906
|
Mouse |
|
|
astrocyte differentiation
|
GO:0048708 |
1 |
0.901
|
Mouse |
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.899
|
Mouse |
|
|
skeletal system morphogenesis
|
GO:0048705 |
102 |
0.898
|
|
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.898
|
|
|
|
somite development
|
GO:0061053 |
96 |
0.897
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
39 |
0.896
|
Human Mouse Rat |
|
|
appendage morphogenesis
|
GO:0035107 |
56 |
0.895
|
Zebrafish Fly |
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
1 |
0.894
|
|
|
|
forebrain regionalization
|
GO:0021871 |
4 |
0.894
|
Mouse |
|
|
positive regulation of gene expression
|
GO:0010628 |
71 |
0.893
|
Human Mouse Rat |
|
|
determination of bilateral symmetry
|
GO:0009855 |
204 |
0.892
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
44 |
0.891
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
3 |
0.891
|
Human Mouse |
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
2 |
0.890
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
143 |
0.890
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
11 |
0.889
|
Human |
|
|
eye development
|
GO:0001654 |
277 |
0.888
|
Fly |
|
|
determination of left right symmetry
|
GO:0007368 |
179 |
0.887
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
104 |
0.884
|
Human |
|
|
multi organism process
|
GO:0051704 |
134 |
0.883
|
Fly |
|
|
negative regulation of kinase activity
|
GO:0033673 |
4 |
0.881
|
|
|
|
stem cell development
|
GO:0048864 |
82 |
0.881
|
Human Mouse Fly |
|
|
regulation of skeletal muscle tissue development
|
GO:0048641 |
4 |
0.880
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
48 |
0.880
|
Human Mouse |
|
|
renal tubule morphogenesis
|
GO:0061333 |
1 |
0.877
|
Mouse Fly |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
2 |
0.876
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
79 |
0.876
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.874
|
|
|
|
cell fate commitment
|
GO:0045165 |
99 |
0.871
|
|
|
|
regulation of ossification
|
GO:0030278 |
5 |
0.871
|
Human Mouse |
|
|
cell cycle
|
GO:0007049 |
93 |
0.870
|
Human |
|
|
cortisol metabolic process
|
GO:0034650 |
2 |
0.869
|
Human |
|
|
gland development
|
GO:0048732 |
143 |
0.863
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.861
|
Human Mouse Fly |
|
|
cortisol biosynthetic process
|
GO:0034651 |
1 |
0.861
|
Human |
|
|
muscle cell differentiation
|
GO:0042692 |
139 |
0.861
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
30 |
0.860
|
|
|
|
somitogenesis
|
GO:0001756 |
87 |
0.860
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
78 |
0.859
|
Human Mouse |
|
|
cell fate specification
|
GO:0001708 |
68 |
0.856
|
|
|
|
regulation of epidermis development
|
GO:0045682 |
2 |
0.855
|
|
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.855
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.852
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
4 |
0.851
|
Human Mouse |
|
|
gliogenesis
|
GO:0042063 |
45 |
0.851
|
Mouse |
|
|
notochord development
|
GO:0030903 |
54 |
0.851
|
|
|
|
single organism nuclear import
|
GO:1902593 |
3 |
0.851
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
17 |
0.838
|
|
|
|
blood vessel development
|
GO:0001568 |
246 |
0.838
|
|
|
|
connective tissue development
|
GO:0061448 |
99 |
0.838
|
Human Mouse |
|
|
dorsal ventral neural tube patterning
|
GO:0021904 |
1 |
0.838
|
|
|
|
forebrain development
|
GO:0030900 |
96 |
0.836
|
Human Mouse |
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.836
|
|
|
|
camera type eye morphogenesis
|
GO:0048593 |
108 |
0.834
|
|
|
|
stem cell maintenance
|
GO:0019827 |
4 |
0.834
|
Fly |
|
|
endocardial cushion morphogenesis
|
GO:0003203 |
3 |
0.833
|
Mouse |
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
1 |
0.832
|
Mouse |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
106 |
0.830
|
|
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.828
|
|
|
|
single organism reproductive process
|
GO:0044702 |
40 |
0.825
|
Rat Fly |
|
|
negative regulation of muscle organ development
|
GO:0048635 |
5 |
0.825
|
Human |
|
|
notochord cell differentiation
|
GO:0060034 |
18 |
0.823
|
Zebrafish |
|
|
regulation of programmed cell death
|
GO:0043067 |
101 |
0.818
|
Human |
|
|
bone development
|
GO:0060348 |
14 |
0.817
|
Human |
|
|
locus ceruleus development
|
GO:0021703 |
3 |
0.817
|
|
|
|
response to lipid
|
GO:0033993 |
60 |
0.816
|
Rat |
|
|
positive regulation of nervous system development
|
GO:0051962 |
25 |
0.815
|
Mouse Rat |
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.814
|
|
|
|
pericardium morphogenesis
|
GO:0003344 |
1 |
0.810
|
|
|
|
otic vesicle development
|
GO:0071599 |
42 |
0.809
|
|
|
|
bone mineralization
|
GO:0030282 |
9 |
0.808
|
Human Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
142 |
0.808
|
|
|
|
rhombomere 5 development
|
GO:0021571 |
4 |
0.805
|
|
|
|
intermediate mesoderm development
|
GO:0048389 |
2 |
0.804
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
52 |
0.803
|
Human |
|
|
response to endogenous stimulus
|
GO:0009719 |
83 |
0.798
|
Human Rat |
|
|
embryonic hemopoiesis
|
GO:0035162 |
53 |
0.797
|
Zebrafish |
|
|
pericardium development
|
GO:0060039 |
1 |
0.794
|
Mouse |
|
|
regulation of embryonic development
|
GO:0045995 |
47 |
0.793
|
|
|
|
heart valve formation
|
GO:0003188 |
4 |
0.792
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
231 |
0.792
|
|
|
|
brain development
|
GO:0007420 |
293 |
0.791
|
Human Mouse |
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.786
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
96 |
0.785
|
Human |
|
|
reproduction
|
GO:0000003 |
40 |
0.785
|
Rat Fly |
|
|
organ formation
|
GO:0048645 |
17 |
0.784
|
|
|
|
vasculature development
|
GO:0001944 |
278 |
0.783
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
7 |
0.781
|
Human |
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
57 |
0.780
|
Human Mouse Rat |
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.778
|
Human |
|
|
craniofacial suture morphogenesis
|
GO:0097094 |
2 |
0.777
|
|
|
|
regulation of wnt signaling pathway involved in heart development
|
GO:0003307 |
2 |
0.777
|
Human |
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
59 |
0.775
|
Human Mouse |
|
|
positive regulation of neurogenesis
|
GO:0050769 |
24 |
0.769
|
Mouse Rat |
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
22 |
0.767
|
Human Mouse Rat |
|
|
protein modification process
|
GO:0036211 |
100 |
0.767
|
Human |
|
|
neural crest cell differentiation
|
GO:0014033 |
72 |
0.765
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
3 |
0.764
|
|
|
|
bone morphogenesis
|
GO:0060349 |
11 |
0.764
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
2 |
0.762
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
2 |
0.758
|
Mouse |
|
|
regulation of transcription involved in primary germ layer cell fate commitment
|
GO:0060796 |
1 |
0.758
|
Zebrafish |
|
|
regulation of immune system process
|
GO:0002682 |
34 |
0.756
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.755
|
Human |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
80 |
0.754
|
Human Mouse |
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
10 |
0.754
|
Human |
|
|
renal system vasculature morphogenesis
|
GO:0061438 |
1 |
0.754
|
|
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.742
|
Mouse |
|
|
biomineral tissue development
|
GO:0031214 |
13 |
0.738
|
Human Mouse |
|
|
determination of heart left right asymmetry
|
GO:0061371 |
117 |
0.738
|
Zebrafish |
|
|
outflow tract morphogenesis
|
GO:0003151 |
1 |
0.737
|
|
|
|
striated muscle cell development
|
GO:0055002 |
108 |
0.733
|
|
|
|
rhombomere development
|
GO:0021546 |
19 |
0.731
|
|
|
|
negative regulation of embryonic development
|
GO:0045992 |
11 |
0.729
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
191 |
0.728
|
Zebrafish Fly |
|
|
cellular component movement
|
GO:0006928 |
335 |
0.726
|
|
|
|
regulation of cell proliferation involved in heart morphogenesis
|
GO:2000136 |
2 |
0.723
|
|
|
|
embryonic retina morphogenesis in camera type eye
|
GO:0060059 |
22 |
0.723
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
23 |
0.721
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
54 |
0.713
|
|
|
|
muscle organ development
|
GO:0007517 |
101 |
0.710
|
Human Mouse Fly |
|
|
nephron morphogenesis
|
GO:0072028 |
2 |
0.709
|
Mouse |
|
|
hepatocyte differentiation
|
GO:0070365 |
1 |
0.709
|
|
|
|
pharyngeal system development
|
GO:0060037 |
18 |
0.708
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
2 |
0.708
|
Rat |
|
|
axis elongation
|
GO:0003401 |
31 |
0.705
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
94 |
0.705
|
Human |
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.703
|
Human Mouse Rat |
|
|
mesodermal to mesenchymal transition involved in gastrulation
|
GO:0060809 |
1 |
0.701
|
|
|
|
endocardial cushion formation
|
GO:0003272 |
2 |
0.700
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
87 |
0.699
|
Human Mouse |
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.699
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.698
|
|
|
|
odontogenesis
|
GO:0042476 |
9 |
0.697
|
Mouse |
|
|
positive regulation of glial cell differentiation
|
GO:0045687 |
1 |
0.696
|
Mouse |
|
|
diencephalon development
|
GO:0021536 |
58 |
0.695
|
Mouse |
|
|
regulation of p38mapk cascade
|
GO:1900744 |
1 |
0.694
|
Human |
|
|
myotube differentiation
|
GO:0014902 |
45 |
0.692
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
2 |
0.689
|
|
|
|
cloaca development
|
GO:0035844 |
9 |
0.688
|
Zebrafish |
|
|
insulin like growth factor receptor signaling pathway
|
GO:0048009 |
4 |
0.687
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
29 |
0.684
|
Human |
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.683
|
Human |
|
|
smooth muscle tissue development
|
GO:0048745 |
1 |
0.681
|
|
|
|
organelle organization
|
GO:0006996 |
227 |
0.681
|
Fly |
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
93 |
0.680
|
Human Mouse Rat |
|
|
cardiac muscle tissue development
|
GO:0048738 |
48 |
0.676
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
21 |
0.674
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
93 |
0.669
|
|
|
|
defense response
|
GO:0006952 |
47 |
0.668
|
Mouse |
|
|
negative regulation of developmental process
|
GO:0051093 |
65 |
0.666
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
48 |
0.666
|
Human Mouse |
|
|
response to fluid shear stress
|
GO:0034405 |
2 |
0.665
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
9 |
0.664
|
|
|
|
locomotion
|
GO:0040011 |
313 |
0.660
|
|
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.656
|
|
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.653
|
Human Mouse Fly |
|
|
positive regulation of cell development
|
GO:0010720 |
25 |
0.650
|
Human Mouse Rat |
|
|
localization of cell
|
GO:0051674 |
244 |
0.649
|
|
|
|
mesodermal cell differentiation
|
GO:0048333 |
21 |
0.646
|
|
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.642
|
|
|
|
tongue morphogenesis
|
GO:0043587 |
3 |
0.641
|
|
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.637
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
11 |
0.637
|
Human |
|
|
lymph vessel development
|
GO:0001945 |
27 |
0.628
|
|
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.627
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.625
|
|
|
|
ectodermal placode formation
|
GO:0060788 |
26 |
0.623
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.618
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
29 |
0.614
|
Human |
|
|
embryonic pectoral fin morphogenesis
|
GO:0035118 |
24 |
0.610
|
|
|
|
atrial ventricular junction remodeling
|
GO:0003294 |
2 |
0.610
|
|
|
|
apoptotic process
|
GO:0006915 |
116 |
0.608
|
Human |
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
90 |
0.604
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
1 |
0.604
|
|
|
|
pectoral fin development
|
GO:0033339 |
50 |
0.601
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
130 |
0.598
|
|
|
|
regulation of cell fate specification
|
GO:0042659 |
20 |
0.596
|
|
|
|
determination of left right asymmetry in lateral mesoderm
|
GO:0003140 |
20 |
0.595
|
|
|
|
response to bacterium
|
GO:0009617 |
58 |
0.591
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
35 |
0.590
|
|
|
|
cardiac cell development
|
GO:0055006 |
21 |
0.590
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
98 |
0.589
|
|
|
|
limb bud formation
|
GO:0060174 |
2 |
0.588
|
|
|
|
immune effector process
|
GO:0002252 |
23 |
0.585
|
|
|
|
c21 steroid hormone metabolic process
|
GO:0008207 |
1 |
0.582
|
Human |
|
|
endochondral bone morphogenesis
|
GO:0060350 |
8 |
0.582
|
|
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.581
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
2 |
0.575
|
|
|
|
rhythmic process
|
GO:0048511 |
21 |
0.574
|
Rat |
|
|
heart formation
|
GO:0060914 |
13 |
0.574
|
|
|
|
immune response
|
GO:0006955 |
28 |
0.573
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
35 |
0.572
|
Rat Fly |
|
|
germ line stem cell maintenance
|
GO:0030718 |
2 |
0.572
|
Fly |
|
|
generation of neurons
|
GO:0048699 |
385 |
0.570
|
Mouse Rat |
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
213 |
0.568
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
274 |
0.567
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
3 |
0.566
|
|
|
|
response to wounding
|
GO:0009611 |
116 |
0.565
|
|
|
|
endoderm development
|
GO:0007492 |
49 |
0.565
|
|
|
|
mesenchymal cell proliferation
|
GO:0010463 |
1 |
0.559
|
Mouse |
|
|
kidney morphogenesis
|
GO:0060993 |
15 |
0.559
|
Mouse |
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
59 |
0.557
|
Human Mouse |
|
|
inner ear receptor cell differentiation
|
GO:0060113 |
29 |
0.557
|
|
|
|
t cell differentiation
|
GO:0030217 |
6 |
0.557
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
55 |
0.555
|
Rat |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.552
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
8 |
0.551
|
Human |
|
|
determination of left right asymmetry in nervous system
|
GO:0035545 |
4 |
0.548
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
56 |
0.541
|
Human Mouse |
|
|
protein destabilization
|
GO:0031648 |
1 |
0.539
|
Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
13 |
0.536
|
|
|
|
mesoderm formation
|
GO:0001707 |
43 |
0.534
|
|
|
|
neural crest cell development
|
GO:0014032 |
62 |
0.532
|
|
|
|
mesendoderm development
|
GO:0048382 |
10 |
0.531
|
|
|
|
gene expression
|
GO:0010467 |
252 |
0.529
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
48 |
0.529
|
Human Mouse |
|
|
nephron epithelium development
|
GO:0072009 |
16 |
0.529
|
Mouse |
|
|
dorsal convergence
|
GO:0060030 |
14 |
0.527
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
77 |
0.525
|
Human Mouse |
|
|
cell migration involved in gastrulation
|
GO:0042074 |
79 |
0.523
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
13 |
0.522
|
|
|
|
determination of liver left right asymmetry
|
GO:0071910 |
11 |
0.520
|
Zebrafish |
|
|
heart looping
|
GO:0001947 |
94 |
0.519
|
Zebrafish |
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
21 |
0.517
|
Human Mouse |
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
68 |
0.515
|
Human Mouse Rat |
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
2 |
0.515
|
|
|
|
atrioventricular valve formation
|
GO:0003190 |
3 |
0.514
|
|
|
|
cardiac chamber development
|
GO:0003205 |
19 |
0.510
|
|
|
|
female gamete generation
|
GO:0007292 |
14 |
0.508
|
Fly |
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
1 |
0.507
|
|
|
|
regulation of cell activation
|
GO:0050865 |
1 |
0.506
|
|
|
|
ketone biosynthetic process
|
GO:0042181 |
2 |
0.505
|
Human |
|
|
protein import into nucleus
|
GO:0006606 |
3 |
0.503
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
26 |
0.497
|
|
|
|
negative regulation of cell fate specification
|
GO:0009996 |
11 |
0.493
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
31 |
0.491
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
69 |
0.491
|
Human Mouse Rat |
|
|
determination of pancreatic left right asymmetry
|
GO:0035469 |
11 |
0.490
|
Zebrafish |
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
4 |
0.489
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
31 |
0.488
|
|
|
|
positive regulation of skeletal muscle tissue development
|
GO:0048643 |
1 |
0.487
|
|
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.484
|
|
|
|
digestive system development
|
GO:0055123 |
289 |
0.482
|
|
|
|
response to growth factor
|
GO:0070848 |
39 |
0.481
|
Human Mouse Rat |
|
|
negative regulation of striated muscle cell differentiation
|
GO:0051154 |
1 |
0.481
|
Human |
|
|
meiotic nuclear division
|
GO:0007126 |
4 |
0.481
|
|
|
|
pituitary gland development
|
GO:0021983 |
16 |
0.478
|
Mouse |
|
|
regulation of cartilage development
|
GO:0061035 |
7 |
0.476
|
Human Mouse |
|
|
muscle cell development
|
GO:0055001 |
115 |
0.474
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
22 |
0.473
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
86 |
0.466
|
Human Mouse |
|
|
regulation of hormone metabolic process
|
GO:0032350 |
6 |
0.463
|
Human |
|
|
regulation of organ growth
|
GO:0046620 |
3 |
0.462
|
Fly |
|
|
kidney development
|
GO:0001822 |
92 |
0.462
|
Zebrafish Mouse |
|
|
negative regulation of nervous system development
|
GO:0051961 |
22 |
0.461
|
|
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.458
|
Mouse |
|
|
tissue remodeling
|
GO:0048771 |
4 |
0.455
|
|
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.454
|
|
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.454
|
Human Mouse Rat |
|
|
auditory receptor cell differentiation
|
GO:0042491 |
15 |
0.450
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
35 |
0.449
|
Human Mouse |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
18 |
0.444
|
Human |
|
|
specification of organ identity
|
GO:0010092 |
2 |
0.444
|
|
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
52 |
0.443
|
|
|
|
response to steroid hormone
|
GO:0048545 |
35 |
0.443
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
52 |
0.440
|
Human Mouse Rat Fly |
|
|
face morphogenesis
|
GO:0060325 |
6 |
0.440
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
68 |
0.439
|
Human Mouse Rat |
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
45 |
0.439
|
Human Mouse |
|
|
amine metabolic process
|
GO:0009308 |
2 |
0.438
|
|
|
|
axial mesoderm formation
|
GO:0048320 |
4 |
0.437
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
13 |
0.437
|
|
|
|
limb morphogenesis
|
GO:0035108 |
7 |
0.437
|
|
|
|
germ cell development
|
GO:0007281 |
22 |
0.436
|
Fly |
|
|
lateral mesoderm development
|
GO:0048368 |
23 |
0.424
|
|
|
|
endocardial cushion development
|
GO:0003197 |
6 |
0.423
|
Mouse |
|
|
regulation of reproductive process
|
GO:2000241 |
4 |
0.423
|
|
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.422
|
Human Mouse |
|
|
convergent extension
|
GO:0060026 |
118 |
0.422
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
97 |
0.421
|
|
|
|
collagen biosynthetic process
|
GO:0032964 |
2 |
0.418
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
3 |
0.417
|
|
|
|
developmental induction
|
GO:0031128 |
10 |
0.414
|
Human |
|
|
cardiac atrium morphogenesis
|
GO:0003209 |
2 |
0.410
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
74 |
0.408
|
|
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.407
|
Human Mouse |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
16 |
0.404
|
Human Mouse |
|
|
tube formation
|
GO:0035148 |
25 |
0.404
|
|
|
|
tube closure
|
GO:0060606 |
1 |
0.404
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
30 |
0.404
|
Human Mouse Rat |
|
|
kidney vasculature morphogenesis
|
GO:0061439 |
1 |
0.396
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
6 |
0.396
|
Human |
|
|
heart valve morphogenesis
|
GO:0003179 |
8 |
0.396
|
Mouse |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.392
|
Human Mouse |
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
45 |
0.392
|
Human Mouse |
|
|
wound healing
|
GO:0042060 |
90 |
0.391
|
|
|
|
regulation of cell death
|
GO:0010941 |
103 |
0.390
|
Human |
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
55 |
0.389
|
Human Mouse |
|
|
alcohol biosynthetic process
|
GO:0046165 |
2 |
0.389
|
Human |
|
|
cerebellum formation
|
GO:0021588 |
2 |
0.388
|
|
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.387
|
Human Mouse Rat |
|
|
regulation of protein binding
|
GO:0043393 |
3 |
0.385
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
14 |
0.383
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
1 |
0.381
|
|
|
|
cell cycle process
|
GO:0022402 |
53 |
0.381
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
45 |
0.379
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.379
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
1 |
0.378
|
|
|
|
monocyte differentiation
|
GO:0030224 |
2 |
0.374
|
|
|
|
nuclear import
|
GO:0051170 |
3 |
0.373
|
|
|
|
muscle tissue development
|
GO:0060537 |
110 |
0.372
|
|
|
|
photoreceptor cell development
|
GO:0042461 |
40 |
0.372
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
1 |
0.368
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
38 |
0.367
|
Fly |
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
55 |
0.367
|
Human Mouse |
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
59 |
0.367
|
Human Mouse Rat |
|
|
negative regulation of map kinase activity
|
GO:0043407 |
2 |
0.367
|
|
|
|
response to other organism
|
GO:0051707 |
97 |
0.366
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.365
|
Mouse Rat |
|
|
regulation of nervous system development
|
GO:0051960 |
90 |
0.362
|
Mouse Rat |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
4 |
0.361
|
|
|
|
cell proliferation involved in heart morphogenesis
|
GO:0061323 |
2 |
0.361
|
|
|
|
invagination involved in gastrulation with mouth forming second
|
GO:0055109 |
1 |
0.360
|
|
|
|
regulation of growth
|
GO:0040008 |
42 |
0.360
|
Fly |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
46 |
0.358
|
|
|
|
determination of left right asymmetry in diencephalon
|
GO:0035462 |
4 |
0.357
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
18 |
0.354
|
|
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.352
|
Rat Fly |
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.351
|
Human Mouse |
|
|
neurological system process
|
GO:0050877 |
62 |
0.347
|
|
|
|
protein import
|
GO:0017038 |
3 |
0.347
|
|
|
|
negative regulation of oocyte development
|
GO:0060283 |
2 |
0.345
|
|
|
|
rhombomere 6 development
|
GO:0021572 |
4 |
0.344
|
|
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.344
|
Human Zebrafish Mouse Rat |
|
|
embryonic skeletal joint morphogenesis
|
GO:0060272 |
3 |
0.341
|
|
|
|
atrioventricular valve morphogenesis
|
GO:0003181 |
6 |
0.341
|
Mouse |
