Danio rerio

0 known processes

bmp7b

bone morphogenetic protein 7b

(Aliases: zgc:153025)

bmp7b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
embryonic organ development GO:0048568 381 0.866
Zebrafish Mouse
mesenchymal cell proliferation GO:0010463 1 0.613
Mouse
digestive tract morphogenesis GO:0048546 231 0.556
Zebrafish Mouse
sensory organ morphogenesis GO:0090596 200 0.533
Zebrafish Mouse
heart development GO:0007507 313 0.427
Zebrafish
specification of symmetry GO:0009799 204 0.403
Zebrafish
striated muscle tissue development GO:0014706 110 0.394
Zebrafish
negative regulation of biological process GO:0048519 304 0.393
Human Zebrafish Mouse Fly
retina development in camera type eye GO:0060041 146 0.334
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.330
Zebrafish Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.329
determination of left right symmetry GO:0007368 179 0.326
Zebrafish
central nervous system development GO:0007417 387 0.311
muscle structure development GO:0061061 196 0.302
Zebrafish Fly
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.276
Zebrafish
skeletal system development GO:0001501 181 0.274
Zebrafish Mouse
retina morphogenesis in camera type eye GO:0060042 79 0.259
Zebrafish
positive regulation of muscle organ development GO:0048636 1 0.240
Fly
sensory organ development GO:0007423 393 0.225
Zebrafish Mouse
digestive system development GO:0055123 289 0.208
Zebrafish Mouse
chordate embryonic development GO:0043009 271 0.204
Zebrafish Mouse
regulation of bone mineralization GO:0030500 2 0.201
Human
regulation of anatomical structure morphogenesis GO:0022603 130 0.196
Zebrafish Mouse
response to virus GO:0009615 21 0.195
regulation of cell differentiation GO:0045595 142 0.190
Human Zebrafish Mouse
cardiac muscle tissue development GO:0048738 48 0.187
regulation of developmental process GO:0050793 247 0.175
Human Zebrafish Mouse Fly
head development GO:0060322 303 0.171
cilium morphogenesis GO:0060271 85 0.171
localization of cell GO:0051674 244 0.169
regionalization GO:0003002 274 0.169
Zebrafish Fly
regulation of multicellular organismal process GO:0051239 277 0.168
Human Zebrafish Mouse Fly
endoderm development GO:0007492 49 0.154
Zebrafish
regulation of biomineral tissue development GO:0070167 2 0.151
Human
establishment of localization GO:0051234 244 0.145
Fly
cellular component movement GO:0006928 335 0.145
Zebrafish Mouse
brain development GO:0007420 293 0.145
muscle tissue development GO:0060537 110 0.140
Zebrafish
cellular aromatic compound metabolic process GO:0006725 295 0.138
Human Zebrafish Mouse
pathway restricted smad protein phosphorylation GO:0060389 1 0.138
Human
determination of bilateral symmetry GO:0009855 204 0.135
Zebrafish
system process GO:0003008 185 0.135
glandular epithelial cell differentiation GO:0002067 9 0.132
enzyme linked receptor protein signaling pathway GO:0007167 106 0.128
Human Zebrafish Mouse
positive regulation of transport GO:0051050 2 0.122
eye development GO:0001654 277 0.121
Zebrafish Mouse
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.121
regulation of production of molecular mediator of immune response GO:0002700 1 0.118
inner ear development GO:0048839 126 0.115
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.114
Human Zebrafish
response to alkaloid GO:0043279 2 0.113
inner ear morphogenesis GO:0042472 63 0.113
positive regulation of secretion by cell GO:1903532 1 0.111
tissue remodeling GO:0048771 4 0.111
positive regulation of signal transduction GO:0009967 56 0.103
Human Zebrafish
camera type eye development GO:0043010 222 0.101
Zebrafish Mouse
positive regulation of cell proliferation GO:0008284 15 0.099
neural tube patterning GO:0021532 33 0.094
response to growth factor GO:0070848 39 0.093
anatomical structure homeostasis GO:0060249 36 0.090
Zebrafish
exocrine system development GO:0035272 28 0.083
Mouse
response to glucose GO:0009749 3 0.077
response to other organism GO:0051707 97 0.077
gastrulation GO:0007369 208 0.077
Zebrafish Mouse
regulation of cellular metabolic process GO:0031323 320 0.077
Human Zebrafish Mouse
nephron morphogenesis GO:0072028 2 0.076
Mouse
fin morphogenesis GO:0033334 53 0.074
cellular response to external stimulus GO:0071496 2 0.074
macromolecule biosynthetic process GO:0009059 227 0.072
Human Zebrafish Mouse
defense response to gram negative bacterium GO:0050829 8 0.072
embryonic limb morphogenesis GO:0030326 2 0.072
Mouse
protein complex biogenesis GO:0070271 30 0.070
Zebrafish
stem cell proliferation GO:0072089 4 0.069
Mouse
positive regulation of cell substrate adhesion GO:0010811 1 0.068
cellular response to endogenous stimulus GO:0071495 68 0.068
Human
cellular response to organic substance GO:0071310 105 0.068
Human
response to endogenous stimulus GO:0009719 83 0.067
Human
cellular amino acid biosynthetic process GO:0008652 2 0.064
production of molecular mediator of immune response GO:0002440 2 0.063
semicircular canal morphogenesis GO:0048752 18 0.063
negative regulation of cellular metabolic process GO:0031324 77 0.063
Human
urogenital system development GO:0001655 97 0.062
Human Mouse
growth GO:0040007 174 0.062
Fly
nucleic acid metabolic process GO:0090304 244 0.062
Human Zebrafish Mouse
cell proliferation GO:0008283 80 0.062
Human Zebrafish Mouse
regulation of signal transduction GO:0009966 225 0.061
Human Zebrafish Mouse
mesenchyme development GO:0060485 127 0.060
Human Mouse
bmp signaling pathway GO:0030509 52 0.059
Human Zebrafish Mouse
otolith development GO:0048840 32 0.059
cellular macromolecule biosynthetic process GO:0034645 224 0.059
Human Zebrafish Mouse
cell projection organization GO:0030030 284 0.057
Human Zebrafish Mouse
digestive tract development GO:0048565 265 0.056
Zebrafish Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.056
Zebrafish Mouse
signal transduction GO:0007165 455 0.055
Human Zebrafish Mouse
muscle cell differentiation GO:0042692 139 0.055
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.055
Human Zebrafish Mouse
cell surface receptor signaling pathway GO:0007166 325 0.054
Human Zebrafish Mouse
camera type eye morphogenesis GO:0048593 108 0.054
Zebrafish Mouse
cell motility GO:0048870 244 0.054
transport GO:0006810 220 0.053
Fly
organic substance biosynthetic process GO:1901576 289 0.052
Human Zebrafish Mouse
cellular response to hormone stimulus GO:0032870 39 0.052
Human
regulation of cell substrate adhesion GO:0010810 1 0.052
i kappab kinase nf kappab signaling GO:0007249 4 0.052
generation of neurons GO:0048699 385 0.051
Human Zebrafish Mouse
larval development GO:0002164 2 0.051
positive regulation of protein metabolic process GO:0051247 23 0.050
Human
embryonic camera type eye development GO:0031076 29 0.050
Zebrafish Mouse
positive regulation of stem cell proliferation GO:2000648 1 0.050
erk1 and erk2 cascade GO:0070371 4 0.049
membrane hyperpolarization GO:0060081 1 0.049
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.049
ear morphogenesis GO:0042471 64 0.048
blood vessel development GO:0001568 246 0.048
Human Zebrafish
regulation of epithelial to mesenchymal transition GO:0010717 3 0.047
gene expression GO:0010467 252 0.047
Human Zebrafish Mouse Fly
anterior posterior pattern specification GO:0009952 152 0.047
neuron development GO:0048666 262 0.046
Human Zebrafish Mouse
regulation of hormone secretion GO:0046883 2 0.046
autophagy GO:0006914 4 0.046
regulation of stem cell proliferation GO:0072091 2 0.045
eye morphogenesis GO:0048592 144 0.044
Zebrafish Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.044
protein localization to plasma membrane GO:0072659 1 0.043
neutral amino acid transport GO:0015804 2 0.043
cartilage development GO:0051216 96 0.043
response to bacterium GO:0009617 58 0.043
endodermal cell differentiation GO:0035987 19 0.042
Zebrafish
cardiocyte differentiation GO:0035051 44 0.042
cell matrix adhesion GO:0007160 4 0.042
regulation of signaling GO:0023051 235 0.042
Human Zebrafish Mouse Fly
cell fate commitment GO:0045165 99 0.041
Zebrafish
positive regulation of secretion GO:0051047 1 0.041
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.041
glomerulus vasculature development GO:0072012 2 0.040
Human
embryo development ending in birth or egg hatching GO:0009792 271 0.040
Zebrafish Mouse
regulation of cell communication GO:0010646 232 0.039
Human Zebrafish Mouse Fly
response to organic cyclic compound GO:0014070 51 0.039
Human
fin development GO:0033333 77 0.039
determination of heart left right asymmetry GO:0061371 117 0.039
Zebrafish
heterocycle metabolic process GO:0046483 290 0.038
Human Zebrafish Mouse
blood circulation GO:0008015 87 0.038
regulation of gene expression GO:0010468 265 0.038
Human Zebrafish Mouse Fly
vasculature development GO:0001944 278 0.038
Human Zebrafish
striated muscle cell differentiation GO:0051146 129 0.037
Zebrafish
response to external stimulus GO:0009605 264 0.037
Zebrafish Mouse
response to vitamin GO:0033273 3 0.037
neural nucleus development GO:0048857 15 0.036
response to nutrient GO:0007584 3 0.036
regulation of macromolecule biosynthetic process GO:0010556 225 0.036
Human Zebrafish Mouse
positive regulation of immune effector process GO:0002699 3 0.036
regulation of chondrocyte differentiation GO:0032330 1 0.036
regulation of rna biosynthetic process GO:2001141 213 0.036
Human Zebrafish Mouse
peptide metabolic process GO:0006518 1 0.036
rostrocaudal neural tube patterning GO:0021903 29 0.036
aromatic compound biosynthetic process GO:0019438 217 0.036
Human Zebrafish Mouse
circulatory system process GO:0003013 87 0.036
single organism localization GO:1902578 225 0.035
Fly
negative regulation of chemotaxis GO:0050922 4 0.035
cell fate specification GO:0001708 68 0.035
Zebrafish
appendage development GO:0048736 80 0.035
Mouse Fly
atp catabolic process GO:0006200 4 0.035
organic acid metabolic process GO:0006082 31 0.035
aging GO:0007568 2 0.035
formation of primary germ layer GO:0001704 62 0.035
Zebrafish Mouse
positive regulation of cell communication GO:0010647 56 0.035
Human Zebrafish
carboxylic acid metabolic process GO:0019752 22 0.035
positive regulation of biological process GO:0048518 253 0.035
Human Zebrafish Mouse Fly
embryonic eye morphogenesis GO:0048048 30 0.035
Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.034
cardiac muscle cell differentiation GO:0055007 30 0.034
response to corticosteroid GO:0031960 1 0.033
negative regulation of cell death GO:0060548 60 0.033
Human Mouse
viral process GO:0016032 1 0.033
renal system development GO:0072001 94 0.033
Human Mouse
regulation of localization GO:0032879 104 0.032
Fly
hormone biosynthetic process GO:0042446 3 0.032
angiogenesis GO:0001525 158 0.032
skeletal system morphogenesis GO:0048705 102 0.032
Zebrafish Mouse
cell substrate adhesion GO:0031589 4 0.031
response to steroid hormone GO:0048545 35 0.031
Human
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.031
regulation of cell activation GO:0050865 1 0.031
hindbrain development GO:0030902 91 0.030
embryonic pectoral fin morphogenesis GO:0035118 24 0.030
cellular response to chemical stimulus GO:0070887 157 0.030
Human
regulation of cellular biosynthetic process GO:0031326 245 0.030
Human Zebrafish Mouse
semicircular canal development GO:0060872 24 0.030
positive regulation of response to stimulus GO:0048584 80 0.030
Human Zebrafish
chondrocyte development GO:0002063 4 0.030
regulation of cell death GO:0010941 103 0.030
Human Mouse
positive regulation of muscle tissue development GO:1901863 1 0.030
specification of axis polarity GO:0065001 4 0.030
peripheral nervous system development GO:0007422 55 0.030
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.029
rna metabolic process GO:0016070 219 0.029
Human Zebrafish Mouse
peptide transport GO:0015833 1 0.029
regulation of carbohydrate metabolic process GO:0006109 4 0.029
pancreas development GO:0031016 84 0.029
septum transversum development GO:0003343 4 0.029
response to molecule of bacterial origin GO:0002237 14 0.029
renal system vasculature development GO:0061437 2 0.028
Human
embryonic cranial skeleton morphogenesis GO:0048701 90 0.028
Zebrafish
positive regulation of protein polymerization GO:0032273 2 0.028
direct ossification GO:0036072 3 0.028
regulation of nitrogen compound metabolic process GO:0051171 251 0.028
Human Zebrafish Mouse
cell migration GO:0016477 237 0.028
neural tube development GO:0021915 62 0.027
diencephalon development GO:0021536 58 0.027
connective tissue development GO:0061448 99 0.027
Human
ectodermal placode development GO:0071696 37 0.027
developmental cell growth GO:0048588 52 0.027
hormone transport GO:0009914 2 0.027
single organism transport GO:0044765 206 0.027
Fly
regulation of cell proliferation GO:0042127 37 0.027
Human Zebrafish Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.026
protein complex subunit organization GO:0071822 46 0.026
Zebrafish
neural crest cell migration GO:0001755 42 0.026
negative regulation of gastrulation GO:2000542 11 0.026
Zebrafish
positive regulation of epithelial cell migration GO:0010634 2 0.026
amino acid transport GO:0006865 2 0.026
odontogenesis of dentin containing tooth GO:0042475 1 0.026
Mouse
response to nicotine GO:0035094 2 0.026
response to chemical GO:0042221 320 0.025
Human Zebrafish Mouse
limb bud formation GO:0060174 2 0.025
cell death GO:0008219 121 0.025
Human Mouse
negative regulation of epithelial cell proliferation GO:0050680 1 0.025
appendage morphogenesis GO:0035107 56 0.025
Mouse Fly
midbrain hindbrain boundary development GO:0030917 23 0.025
interaction with host GO:0051701 4 0.025
ear development GO:0043583 127 0.025
lateral line system development GO:0048925 76 0.025
skeletal muscle tissue development GO:0007519 67 0.025
Zebrafish
synaptic target recognition GO:0008039 1 0.025
positive regulation of cell migration GO:0030335 11 0.025
oxoacid metabolic process GO:0043436 31 0.025
otic vesicle morphogenesis GO:0071600 34 0.024
cellular response to stress GO:0033554 62 0.024
response to carbohydrate GO:0009743 3 0.024
cellular response to growth factor stimulus GO:0071363 39 0.024
tube morphogenesis GO:0035239 349 0.024
Zebrafish Mouse
positive regulation of multi organism process GO:0043902 3 0.024
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.024
regulation of transcription dna templated GO:0006355 213 0.024
Human Zebrafish Mouse
cell morphogenesis GO:0000902 289 0.024
Human Zebrafish Mouse
biosynthetic process GO:0009058 294 0.024
Human Zebrafish Mouse
heterocycle biosynthetic process GO:0018130 215 0.024
Human Zebrafish Mouse
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.023
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 10 0.023
Human Zebrafish
determination of dorsal ventral asymmetry GO:0048262 34 0.023
Zebrafish
lymph vessel development GO:0001945 27 0.023
hormone secretion GO:0046879 2 0.023
somite development GO:0061053 96 0.023
nephron development GO:0072006 31 0.023
Human Mouse
regulation of locomotion GO:0040012 55 0.023
hepaticobiliary system development GO:0061008 98 0.023
interspecies interaction between organisms GO:0044419 4 0.023
intramembranous ossification GO:0001957 3 0.022
positive regulation of production of molecular mediator of immune response GO:0002702 1 0.022
regulation of reproductive process GO:2000241 4 0.022
Zebrafish Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.022
Human Zebrafish Mouse
positive regulation of translation GO:0045727 1 0.022
regulation of endodermal cell fate specification GO:0042663 15 0.022
Zebrafish
extracellular matrix organization GO:0030198 27 0.021
death GO:0016265 121 0.021
Human Mouse
hard palate development GO:0060022 4 0.021
negative regulation of growth rate GO:0045967 1 0.021
response to hexose GO:0009746 3 0.021
nucleobase containing compound metabolic process GO:0006139 274 0.021
Human Zebrafish Mouse
respiratory system development GO:0060541 5 0.021
stem cell fate commitment GO:0048865 1 0.021
positive regulation of cell death GO:0010942 29 0.021
Mouse
regulation of biosynthetic process GO:0009889 250 0.020
Human Zebrafish Mouse
apical junction assembly GO:0043297 1 0.020
kidney vasculature development GO:0061440 2 0.020
Human
transmembrane transport GO:0055085 120 0.020
endocardium morphogenesis GO:0003160 4 0.020
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.020
regulation of tissue remodeling GO:0034103 2 0.020
iron ion transport GO:0006826 4 0.020
cellular component morphogenesis GO:0032989 336 0.020
Human Zebrafish Mouse
endochondral bone growth GO:0003416 2 0.020
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.020
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
Human Fly
response to organic substance GO:0010033 153 0.019
Human
adherens junction organization GO:0034332 4 0.019
extrinsic apoptotic signaling pathway GO:0097191 3 0.019
palate development GO:0060021 8 0.019
mechanoreceptor differentiation GO:0042490 37 0.019
negative regulation of cellular process GO:0048523 283 0.019
Human Zebrafish Mouse
positive regulation of signaling GO:0023056 56 0.019
Human Zebrafish
meiotic cell cycle process GO:1903046 3 0.019
cranial suture morphogenesis GO:0060363 1 0.019
semicircular canal formation GO:0060876 4 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
protein secretion GO:0009306 1 0.019
regulation of skeletal muscle tissue development GO:0048641 4 0.019
establishment of epithelial cell polarity GO:0090162 2 0.019
positive regulation of stress activated mapk cascade GO:0032874 3 0.019
regulation of cell matrix adhesion GO:0001952 1 0.019
locomotion GO:0040011 313 0.018
Zebrafish Mouse
craniofacial suture morphogenesis GO:0097094 2 0.018
positive regulation of cell adhesion GO:0045785 1 0.018
Human
regulation of metabolic process GO:0019222 359 0.018
Human Zebrafish Mouse Fly
mechanosensory lateral line system development GO:0048881 49 0.018
regulation of endocrine process GO:0044060 2 0.018
mononuclear cell proliferation GO:0032943 1 0.018
cartilage development involved in endochondral bone morphogenesis GO:0060351 8 0.018
cell cell signaling GO:0007267 52 0.018
Zebrafish Fly
positive regulation of endothelial cell differentiation GO:0045603 2 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
Human Zebrafish Mouse Fly
protein localization to membrane GO:0072657 9 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
peripheral nervous system neuron differentiation GO:0048934 28 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.017
Human
regulation of intracellular signal transduction GO:1902531 57 0.017
Human
negative regulation of striated muscle tissue development GO:0045843 2 0.017
exocrine pancreas development GO:0031017 28 0.017
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.017
dorsal ventral pattern formation GO:0009953 125 0.017
Zebrafish Fly
regulation of cytoplasmic transport GO:1903649 4 0.017
regulation of bone remodeling GO:0046850 2 0.017
protein metabolic process GO:0019538 183 0.017
Human
cellular response to molecule of bacterial origin GO:0071219 3 0.016
modulation by virus of host morphology or physiology GO:0019048 1 0.016
regulation of phospholipase activity GO:0010517 2 0.016
b cell activation GO:0042113 2 0.016
bone morphogenesis GO:0060349 11 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
Human Zebrafish Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.016
Fly
positive regulation of apoptotic signaling pathway GO:2001235 1 0.016
developmental growth involved in morphogenesis GO:0060560 86 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
Human Zebrafish Mouse
cell cell junction organization GO:0045216 10 0.016
neuron fate specification GO:0048665 20 0.016
negative regulation of muscle tissue development GO:1901862 2 0.016
embryonic viscerocranium morphogenesis GO:0048703 52 0.016
blood vessel morphogenesis GO:0048514 216 0.016
Zebrafish
intracellular signal transduction GO:0035556 85 0.016
Human
cell adhesion GO:0007155 40 0.016
Human
cellular amine metabolic process GO:0044106 2 0.016
glucocorticoid biosynthetic process GO:0006704 1 0.016
glial cell differentiation GO:0010001 42 0.015
cellular response to nutrient levels GO:0031669 2 0.015
negative regulation of cell fate commitment GO:0010454 13 0.015
Zebrafish
osteoclast differentiation GO:0030316 1 0.015
lymphangiogenesis GO:0001946 25 0.015
response to drug GO:0042493 3 0.015
midbrain development GO:0030901 28 0.015
regulation of immune system process GO:0002682 34 0.015
cellular protein metabolic process GO:0044267 129 0.015
Human
response to oxygen containing compound GO:1901700 55 0.015
organ regeneration GO:0031100 1 0.015
morphogenesis of an epithelial fold GO:0060571 1 0.015
Mouse
positive regulation of epithelial cell differentiation GO:0030858 2 0.015
regulation of cell migration GO:0030334 40 0.015
mesoderm development GO:0007498 88 0.015
Mouse Fly
zymogen activation GO:0031638 3 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.014
medulla oblongata development GO:0021550 4 0.014
glucocorticoid metabolic process GO:0008211 2 0.014
epithelial cell differentiation GO:0030855 116 0.014
Mouse Fly
regulation of axonogenesis GO:0050770 32 0.014
positive regulation of multicellular organismal process GO:0051240 52 0.014
Human Mouse Fly
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
pericardium morphogenesis GO:0003344 1 0.014
positive regulation of hydrolase activity GO:0051345 13 0.014
regulation of programmed cell death GO:0043067 101 0.014
Mouse
developmental growth GO:0048589 166 0.014
Fly
positive regulation of cell differentiation GO:0045597 30 0.014
Human Mouse
bone remodeling GO:0046849 2 0.014
inositol lipid mediated signaling GO:0048017 2 0.014
cell growth GO:0016049 57 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.014
negative regulation of signaling GO:0023057 96 0.014
Human Mouse
energy reserve metabolic process GO:0006112 2 0.014
positive regulation of striated muscle tissue development GO:0045844 1 0.014
cellular macromolecule metabolic process GO:0044260 391 0.014
Human Zebrafish Mouse
otic vesicle formation GO:0030916 27 0.014
cell cycle arrest GO:0007050 1 0.014
endochondral bone morphogenesis GO:0060350 8 0.014
embryonic neurocranium morphogenesis GO:0048702 15 0.014
regulation of anatomical structure size GO:0090066 33 0.014
membrane repolarization GO:0086009 2 0.014
positive regulation of developmental process GO:0051094 50 0.014
Human Mouse Fly
optomotor response GO:0071632 1 0.014
positive regulation of leukocyte mediated immunity GO:0002705 1 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
Human Zebrafish Mouse
regulation of striated muscle tissue development GO:0016202 6 0.013
positive regulation of defense response GO:0031349 9 0.013
response to monosaccharide GO:0034284 3 0.013
water homeostasis GO:0030104 4 0.013
lymphocyte proliferation GO:0046651 1 0.013
cellular nitrogen compound metabolic process GO:0034641 290 0.013
Human Zebrafish Mouse
negative regulation of oocyte development GO:0060283 2 0.013
Zebrafish
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
mesenchymal cell differentiation GO:0048762 87 0.013
Human
sensory perception GO:0007600 39 0.013
cytokine production involved in immune response GO:0002367 1 0.013
regulation of endothelial cell differentiation GO:0045601 3 0.013
nitrogen compound transport GO:0071705 23 0.013
skeletal muscle organ development GO:0060538 78 0.013
Zebrafish
regulation of cytokine production GO:0001817 3 0.013
epidermis development GO:0008544 48 0.013
myotube cell development GO:0014904 35 0.013
Zebrafish
vestibular receptor cell development GO:0060118 3 0.013
embryonic appendage morphogenesis GO:0035113 30 0.013
Mouse
cellular ketone metabolic process GO:0042180 11 0.013
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.013
cardiac atrium development GO:0003230 4 0.013
regulation of protein transport GO:0051223 3 0.013
multi organism reproductive process GO:0044703 36 0.013
Zebrafish Fly
telomere organization GO:0032200 1 0.013
rhombomere development GO:0021546 19 0.012
neuron projection extension GO:1990138 45 0.012
ameboidal type cell migration GO:0001667 143 0.012
apoptotic process involved in morphogenesis GO:0060561 2 0.012
Mouse
cellular response to lipopolysaccharide GO:0071222 3 0.012
response to nitrogen compound GO:1901698 19 0.012
cartilage condensation GO:0001502 3 0.012
positive regulation of immune system process GO:0002684 17 0.012
regulation of dna replication GO:0006275 3 0.012
heart looping GO:0001947 94 0.012
Zebrafish
positive regulation of neural precursor cell proliferation GO:2000179 1 0.012
carboxylic acid catabolic process GO:0046395 3 0.012
regulation of cellular component size GO:0032535 30 0.012
ncrna metabolic process GO:0034660 12 0.012
cell substrate junction assembly GO:0007044 2 0.012
axis specification GO:0009798 43 0.012
regulation of mesenchymal cell proliferation GO:0010464 1 0.012
neuroblast fate commitment GO:0014017 1 0.012
retinoic acid biosynthetic process GO:0002138 6 0.012
type b pancreatic cell development GO:0003323 4 0.012
cellular hormone metabolic process GO:0034754 19 0.012
neuron differentiation GO:0030182 353 0.012
Human Zebrafish Mouse
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.012
cardiogenic plate morphogenesis GO:0003142 1 0.012
embryonic heart tube development GO:0035050 133 0.012
Zebrafish
gland development GO:0048732 143 0.012
Mouse
positive regulation of programmed cell death GO:0043068 29 0.012
Mouse
regulation of stem cell differentiation GO:2000736 4 0.012
Mouse
modification by symbiont of host morphology or physiology GO:0044003 4 0.012
proepicardium development GO:0003342 4 0.011
hatching GO:0035188 4 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
Human Zebrafish Mouse Fly
regulation of hormone metabolic process GO:0032350 6 0.011
regulation of extent of cell growth GO:0061387 29 0.011
astrocyte differentiation GO:0048708 1 0.011
rhombomere 6 development GO:0021572 4 0.011
positive regulation of defense response to virus by host GO:0002230 0 0.011
phagocytosis GO:0006909 3 0.011
multicellular organismal signaling GO:0035637 22 0.011
regulation of primary metabolic process GO:0080090 311 0.011
Human Zebrafish Mouse
sensory perception of chemical stimulus GO:0007606 3 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
skeletal muscle fiber development GO:0048741 35 0.011
Zebrafish
bone mineralization GO:0030282 9 0.011
Human
regulation of oocyte development GO:0060281 3 0.011
Zebrafish
rhombomere 5 development GO:0021571 4 0.011
regulation of bmp signaling pathway GO:0030510 39 0.011
Zebrafish
pancreatic d cell differentiation GO:0003311 2 0.011
programmed cell death GO:0012501 119 0.011
Mouse
signal transduction in absence of ligand GO:0038034 1 0.011
pancreatic a cell development GO:0003322 2 0.011
positive regulation of locomotion GO:0040017 14 0.011
regulation of wnt signaling pathway GO:0030111 53 0.011
mitotic sister chromatid cohesion GO:0007064 2 0.011
regulation of carbohydrate biosynthetic process GO:0043255 1 0.011
germ cell development GO:0007281 22 0.011
Zebrafish Fly
posterior lateral line system development GO:0048915 46 0.011
cell cycle GO:0007049 93 0.011
Human
regulation of wound healing GO:0061041 2 0.010
regulation of protein complex assembly GO:0043254 3 0.010
embryonic heart tube formation GO:0003144 1 0.010
negative regulation of protein complex assembly GO:0031333 1 0.010
regulation of tube size GO:0035150 2 0.010
bone development GO:0060348 14 0.010
histone h3 k9 methylation GO:0051567 5 0.010
positive regulation of cellular component movement GO:0051272 11 0.010
positive regulation of cell activation GO:0050867 1 0.010
diterpenoid metabolic process GO:0016101 15 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
regulation of heart growth GO:0060420 2 0.010
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.010
ribosomal small subunit biogenesis GO:0042274 2 0.010

bmp7b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
cardiovascular system disease DOID:1287 0 0.036
heart disease DOID:114 0 0.029
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
organ system cancer DOID:0050686 0 0.023
disease of metabolism DOID:0014667 0 0.022
inherited metabolic disorder DOID:655 0 0.022
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
musculoskeletal system disease DOID:17 0 0.012
muscle tissue disease DOID:66 0 0.012
immune system disease DOID:2914 0 0.011