Danio rerio

108 known processes

bmpr2a

bone morphogenetic protein receptor, type II a (serine/threonine kinase)

bmpr2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vasculature development GO:0001944 278 0.611
septum transversum development GO:0003343 4 0.530
Zebrafish
regulation of epithelial cell proliferation GO:0050678 3 0.508
negative regulation of blood circulation GO:1903523 2 0.421
blood vessel morphogenesis GO:0048514 216 0.419
Zebrafish
positive regulation of endothelial cell proliferation GO:0001938 1 0.411
regulation of synapse organization GO:0050807 3 0.410
Fly
negative regulation of cell adhesion GO:0007162 6 0.382
Zebrafish
notochord morphogenesis GO:0048570 17 0.375
nucleobase containing compound biosynthetic process GO:0034654 205 0.368
endothelial cell proliferation GO:0001935 11 0.364
immune system process GO:0002376 241 0.351
Zebrafish
regulation of blood pressure GO:0008217 1 0.338
negative regulation of calcium dependent cell cell adhesion GO:0046588 1 0.318
Zebrafish
gene expression GO:0010467 252 0.315
digestive tract morphogenesis GO:0048546 231 0.308
Zebrafish
regionalization GO:0003002 274 0.293
Zebrafish
heart jogging GO:0003146 40 0.292
embryonic heart tube development GO:0035050 133 0.287
immune system development GO:0002520 191 0.282
Zebrafish
regulation of developmental process GO:0050793 247 0.278
Fly
lymph vessel development GO:0001945 27 0.275
regulation of synapse assembly GO:0051963 3 0.272
Fly
determination of ventral identity GO:0048264 21 0.256
Zebrafish
negative regulation of biological process GO:0048519 304 0.255
Zebrafish
artery development GO:0060840 22 0.255
Zebrafish
determination of left right asymmetry in nervous system GO:0035545 4 0.252
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.248
regulation of response to stimulus GO:0048583 269 0.247
Zebrafish
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.245
Fly
tissue remodeling GO:0048771 4 0.238
hematopoietic or lymphoid organ development GO:0048534 191 0.235
Zebrafish
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.233
negative regulation of cellular process GO:0048523 283 0.233
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.232
Fly
macromolecule biosynthetic process GO:0009059 227 0.230
organic cyclic compound biosynthetic process GO:1901362 223 0.224
dorsal ventral pattern formation GO:0009953 125 0.221
Zebrafish
cellular biosynthetic process GO:0044249 286 0.217
localization of cell GO:0051674 244 0.217
Zebrafish
regulation of gene expression GO:0010468 265 0.215
nucleic acid templated transcription GO:0097659 181 0.214
embryonic medial fin morphogenesis GO:0035122 6 0.213
Zebrafish
synaptic growth at neuromuscular junction GO:0051124 2 0.211
Fly
epithelial tube morphogenesis GO:0060562 148 0.210
gastrulation GO:0007369 208 0.210
Zebrafish
signal transduction GO:0007165 455 0.209
pathway restricted smad protein phosphorylation GO:0060389 1 0.208
positive regulation of epithelial cell proliferation GO:0050679 1 0.207
regulation of macromolecule biosynthetic process GO:0010556 225 0.207
regulation of tube size GO:0035150 2 0.206
Zebrafish
positive regulation of cellular component biogenesis GO:0044089 3 0.206
Fly
ameboidal type cell migration GO:0001667 143 0.204
Zebrafish
lymph vessel morphogenesis GO:0036303 25 0.202
determination of left right symmetry GO:0007368 179 0.202
sensory organ development GO:0007423 393 0.201
response to fluid shear stress GO:0034405 2 0.201
Zebrafish
positive regulation of synapse assembly GO:0051965 1 0.198
Fly
embryonic organ development GO:0048568 381 0.197
regulation of systemic arterial blood pressure GO:0003073 1 0.196
tube morphogenesis GO:0035239 349 0.196
left right pattern formation GO:0060972 19 0.195
Zebrafish
cellular response to external stimulus GO:0071496 2 0.191
hemopoiesis GO:0030097 183 0.187
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.179
biosynthetic process GO:0009058 294 0.179
diencephalon development GO:0021536 58 0.176
Zebrafish
cellular nitrogen compound biosynthetic process GO:0044271 218 0.175
cell migration involved in gastrulation GO:0042074 79 0.173
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.172
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.169
Fly
cellular response to nutrient levels GO:0031669 2 0.169
lymphangiogenesis GO:0001946 25 0.168
heart looping GO:0001947 94 0.167
aromatic compound biosynthetic process GO:0019438 217 0.164
regulation of biosynthetic process GO:0009889 250 0.163
embryonic hemopoiesis GO:0035162 53 0.162
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.161
forebrain development GO:0030900 96 0.158
Zebrafish
heart morphogenesis GO:0003007 156 0.157
convergent extension involved in gastrulation GO:0060027 71 0.155
Zebrafish
regulation of nitrogen compound metabolic process GO:0051171 251 0.154
digestive system development GO:0055123 289 0.154
Zebrafish
regulation of cell adhesion GO:0030155 15 0.152
Zebrafish
determination of dorsal ventral asymmetry GO:0048262 34 0.151
Zebrafish
brain development GO:0007420 293 0.149
Zebrafish
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.148
Zebrafish
cell morphogenesis GO:0000902 289 0.147
gland development GO:0048732 143 0.146
Zebrafish
locomotion GO:0040011 313 0.144
Zebrafish
camera type eye development GO:0043010 222 0.143
cellular component morphogenesis GO:0032989 336 0.141
regulation of nervous system development GO:0051960 90 0.140
Fly
cellular macromolecule metabolic process GO:0044260 391 0.139
cellular component movement GO:0006928 335 0.137
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.135
regulation of multicellular organismal development GO:2000026 223 0.135
Fly
cell projection morphogenesis GO:0048858 244 0.134
positive regulation of endothelial cell migration GO:0010595 2 0.133
retina development in camera type eye GO:0060041 146 0.133
caudal fin development GO:0033336 9 0.133
Zebrafish
rna biosynthetic process GO:0032774 181 0.132
cellular macromolecule biosynthetic process GO:0034645 224 0.130
hepaticobiliary system development GO:0061008 98 0.130
Zebrafish
embryonic heart tube morphogenesis GO:0003143 108 0.129
regulation of rna biosynthetic process GO:2001141 213 0.127
mesenchyme development GO:0060485 127 0.127
Zebrafish
regulation of biomineral tissue development GO:0070167 2 0.125
wound healing GO:0042060 90 0.122
Zebrafish
bone mineralization GO:0030282 9 0.122
response to external stimulus GO:0009605 264 0.120
rna metabolic process GO:0016070 219 0.117
cell cell signaling involved in cell fate commitment GO:0045168 12 0.114
Fly
cartilage development GO:0051216 96 0.113
Zebrafish
regulation of biological quality GO:0065008 263 0.111
Zebrafish Fly
regeneration GO:0031099 91 0.106
Zebrafish
regulation of cell differentiation GO:0045595 142 0.104
positive regulation of epithelial cell migration GO:0010634 2 0.104
pericardium development GO:0060039 1 0.102
skeletal system development GO:0001501 181 0.101
Zebrafish
fin morphogenesis GO:0033334 53 0.099
Zebrafish
cell part morphogenesis GO:0032990 246 0.099
cell motility GO:0048870 244 0.099
Zebrafish
endoderm development GO:0007492 49 0.096
Zebrafish
cellular response to extracellular stimulus GO:0031668 2 0.096
cell projection organization GO:0030030 284 0.095
digestive tract development GO:0048565 265 0.095
Zebrafish
axon guidance GO:0007411 86 0.095
regulation of neurogenesis GO:0050767 87 0.093
biomineral tissue development GO:0031214 13 0.092
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.091
endoderm formation GO:0001706 29 0.090
Zebrafish
epithelial cell migration GO:0010631 25 0.090
caudal fin morphogenesis GO:0035143 7 0.089
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.087
regulation of cell communication GO:0010646 232 0.087
Zebrafish
transcription dna templated GO:0006351 181 0.086
determination of dorsal identity GO:0048263 13 0.086
Zebrafish
neuromuscular synaptic transmission GO:0007274 2 0.086
Fly
regulation of signaling GO:0023051 235 0.085
Zebrafish
convergent extension GO:0060026 118 0.084
Zebrafish
regulation of bone mineralization GO:0030500 2 0.083
cell fate commitment GO:0045165 99 0.082
Zebrafish Fly
eye development GO:0001654 277 0.081
synaptic transmission GO:0007268 35 0.081
Fly
tissue migration GO:0090130 37 0.079
blood vessel development GO:0001568 246 0.078
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.078
regulation of cell development GO:0060284 100 0.078
endodermal cell differentiation GO:0035987 19 0.078
Zebrafish
regulation of axon extension GO:0030516 24 0.076
regulation of cell motility GO:2000145 46 0.075
cellular response to starvation GO:0009267 1 0.075
neuron differentiation GO:0030182 353 0.075
regulation of cellular metabolic process GO:0031323 320 0.075
neuron projection guidance GO:0097485 86 0.075
regulation of axonogenesis GO:0050770 32 0.075
chondrocyte development GO:0002063 4 0.075
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.074
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.073
endothelium development GO:0003158 25 0.073
regulation of metabolic process GO:0019222 359 0.072
generation of neurons GO:0048699 385 0.072
lateral mesoderm development GO:0048368 23 0.071
Zebrafish
regulation of neuron differentiation GO:0045664 56 0.071
dorsal convergence GO:0060030 14 0.070
Zebrafish
circulatory system process GO:0003013 87 0.069
Zebrafish
response to chemical GO:0042221 320 0.069
bmp signaling pathway GO:0030509 52 0.069
heterocycle biosynthetic process GO:0018130 215 0.069
chemosensory behavior GO:0007635 1 0.067
regulation of primary metabolic process GO:0080090 311 0.067
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.066
fin regeneration GO:0031101 51 0.066
Zebrafish
appendage development GO:0048736 80 0.065
Zebrafish
negative regulation of epithelial cell proliferation GO:0050680 1 0.065
chemotaxis GO:0006935 104 0.064
heterocycle metabolic process GO:0046483 290 0.064
venous blood vessel development GO:0060841 9 0.063
vascular process in circulatory system GO:0003018 6 0.063
Zebrafish
negative regulation of macromolecule metabolic process GO:0010605 76 0.063
mesoderm formation GO:0001707 43 0.062
Zebrafish
neuron projection morphogenesis GO:0048812 161 0.061
neuron projection development GO:0031175 180 0.061
transcription from rna polymerase ii promoter GO:0006366 80 0.061
positive regulation of axon extension GO:0045773 5 0.060
central nervous system development GO:0007417 387 0.059
Zebrafish
positive regulation of response to external stimulus GO:0032103 9 0.058
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.058
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.057
negative regulation of cell cell adhesion GO:0022408 6 0.057
Zebrafish
endodermal cell fate commitment GO:0001711 18 0.056
Zebrafish
regulation of calcium dependent cell cell adhesion GO:0046586 1 0.055
Zebrafish
response to wounding GO:0009611 116 0.055
Zebrafish
phosphorus metabolic process GO:0006793 109 0.054
positive regulation of secretion GO:0051047 1 0.054
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 10 0.053
endothelial cell migration GO:0043542 19 0.053
morphogenesis of an epithelium GO:0002009 333 0.052
tissue regeneration GO:0042246 74 0.051
Zebrafish
cell cell signaling GO:0007267 52 0.051
Fly
regulation of response to external stimulus GO:0032101 31 0.051
organic substance biosynthetic process GO:1901576 289 0.051
cellular component biogenesis GO:0044085 178 0.050
Zebrafish Fly
regulation of cell projection organization GO:0031344 44 0.050
negative regulation of metabolic process GO:0009892 86 0.049
nucleocytoplasmic transport GO:0006913 4 0.049
positive regulation of signaling GO:0023056 56 0.049
sequestering of calcium ion GO:0051208 3 0.048
regulation of neuron projection development GO:0010975 40 0.048
axonogenesis GO:0007409 152 0.048
regulation of cell migration GO:0030334 40 0.048
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.047
Zebrafish
cardiac chamber development GO:0003205 19 0.046
Zebrafish
neuron development GO:0048666 262 0.046
endocrine process GO:0050886 2 0.046
regulation of signal transduction GO:0009966 225 0.045
Zebrafish
central nervous system formation GO:0021556 1 0.045
Zebrafish
macromolecule modification GO:0043412 111 0.045
cellular nitrogen compound metabolic process GO:0034641 290 0.045
angiogenesis GO:0001525 158 0.044
cell proliferation GO:0008283 80 0.044
regulation of localization GO:0032879 104 0.044
regulation of cell size GO:0008361 29 0.044
sprouting angiogenesis GO:0002040 53 0.044
positive regulation of developmental process GO:0051094 50 0.044
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.043
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.043
Zebrafish
positive regulation of nervous system development GO:0051962 25 0.043
Fly
negative regulation of dna metabolic process GO:0051053 4 0.042
tyrosine phosphorylation of stat protein GO:0007260 1 0.042
epithelium migration GO:0090132 25 0.041
nitrogen compound metabolic process GO:0006807 319 0.041
regulation of cellular component movement GO:0051270 55 0.041
retina vasculature development in camera type eye GO:0061298 2 0.041
positive regulation of cell projection organization GO:0031346 9 0.040
cellular aromatic compound metabolic process GO:0006725 295 0.039
regulation of anatomical structure morphogenesis GO:0022603 130 0.039
erythrocyte homeostasis GO:0034101 55 0.039
formation of primary germ layer GO:0001704 62 0.039
Zebrafish
taxis GO:0042330 109 0.039
lateral inhibition GO:0046331 1 0.038
Fly
neuron projection extension GO:1990138 45 0.038
nucleic acid metabolic process GO:0090304 244 0.037
stem cell differentiation GO:0048863 117 0.037
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.037
calcium ion transport into cytosol GO:0060402 3 0.036
cell morphogenesis involved in differentiation GO:0000904 195 0.036
regulation of locomotion GO:0040012 55 0.035
single organism nuclear import GO:1902593 3 0.035
system process GO:0003008 185 0.035
Zebrafish
negative regulation of protein phosphorylation GO:0001933 4 0.035
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.035
positive regulation of cellular component movement GO:0051272 11 0.034
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.034
regulation of establishment of protein localization GO:0070201 4 0.034
dna metabolic process GO:0006259 27 0.034
protein modification process GO:0036211 100 0.034
positive regulation of transport GO:0051050 2 0.033
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.033
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.033
epithelial cell differentiation GO:0030855 116 0.033
endodermal cell fate determination GO:0007493 2 0.033
Zebrafish
positive regulation of biological process GO:0048518 253 0.033
Fly
regulation of cellular biosynthetic process GO:0031326 245 0.032
embryonic appendage morphogenesis GO:0035113 30 0.032
Zebrafish
stem cell proliferation GO:0072089 4 0.032
appendage morphogenesis GO:0035107 56 0.032
Zebrafish
epithelial cell proliferation GO:0050673 17 0.032
negative regulation of cellular biosynthetic process GO:0031327 55 0.031
positive regulation of neuron projection development GO:0010976 9 0.031
regulation of metal ion transport GO:0010959 4 0.031
protein metabolic process GO:0019538 183 0.030
regulation of cellular component organization GO:0051128 86 0.030
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.030
single organismal cell cell adhesion GO:0016337 29 0.030
Zebrafish
response to external biotic stimulus GO:0043207 97 0.029
phosphorylation GO:0016310 69 0.029
lymphatic endothelial cell differentiation GO:0060836 1 0.028
protein phosphorylation GO:0006468 47 0.028
odontogenesis GO:0042476 9 0.028
Zebrafish
positive regulation of response to stimulus GO:0048584 80 0.028
head development GO:0060322 303 0.028
Zebrafish
negative regulation of cellular metabolic process GO:0031324 77 0.028
axon development GO:0061564 166 0.028
protein complex disassembly GO:0043241 1 0.027
regulation of production of molecular mediator of immune response GO:0002700 1 0.027
locomotor rhythm GO:0045475 3 0.027
regulation of sequestering of calcium ion GO:0051282 4 0.027
synapse assembly GO:0007416 9 0.027
Fly
ossification GO:0001503 23 0.026
regulation of cell proliferation GO:0042127 37 0.026
cytosolic calcium ion transport GO:0060401 3 0.026
embryonic heart tube left right pattern formation GO:0060971 5 0.026
Zebrafish
regulation of behavior GO:0050795 24 0.026
positive regulation of secretion by cell GO:1903532 1 0.026
stem cell maintenance GO:0019827 4 0.026
protein localization to nucleus GO:0034504 3 0.025
behavior GO:0007610 74 0.025
death GO:0016265 121 0.025
positive regulation of jak stat cascade GO:0046427 2 0.025
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.025
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.025
Zebrafish
negative regulation of kinase activity GO:0033673 4 0.025
endothelial cell differentiation GO:0045446 20 0.025
regulation of epithelial cell migration GO:0010632 5 0.025
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.025
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.024
multicellular organism growth GO:0035264 4 0.024
negative regulation of biosynthetic process GO:0009890 55 0.024
positive regulation of signal transduction GO:0009967 56 0.024
cell migration GO:0016477 237 0.024
Zebrafish
protein secretion GO:0009306 1 0.024
neuromuscular junction development GO:0007528 9 0.024
Fly
embryonic caudal fin morphogenesis GO:0035124 3 0.024
Zebrafish
response to stress GO:0006950 263 0.024
Zebrafish
regulation of phosphorus metabolic process GO:0051174 43 0.023
developmental growth involved in morphogenesis GO:0060560 86 0.023
regulation of protein transport GO:0051223 3 0.023
regulation of immune system process GO:0002682 34 0.023
positive regulation of bmp signaling pathway GO:0030513 10 0.023
regulation of system process GO:0044057 40 0.023
nuclear import GO:0051170 3 0.023
negative regulation of immune response GO:0050777 2 0.023
limb development GO:0060173 8 0.023
regulation of erythrocyte differentiation GO:0045646 2 0.023
cellular response to xenobiotic stimulus GO:0071466 35 0.023
maintenance of location GO:0051235 4 0.023
positive regulation of rho protein signal transduction GO:0035025 0 0.022
extrinsic apoptotic signaling pathway GO:0097191 3 0.022
myeloid cell differentiation GO:0030099 86 0.022
negative regulation of cell differentiation GO:0045596 46 0.022
adherens junction organization GO:0034332 4 0.022
osteoblast differentiation GO:0001649 5 0.022
determination of left right asymmetry in diencephalon GO:0035462 4 0.021
Zebrafish
aging GO:0007568 2 0.021
regulation of dna metabolic process GO:0051052 11 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
regulation of vasculature development GO:1901342 33 0.020
regulation of endocrine process GO:0044060 2 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
developmental cell growth GO:0048588 52 0.020
positive regulation of neurogenesis GO:0050769 24 0.020
single organism metabolic process GO:0044710 217 0.020
protein complex subunit organization GO:0071822 46 0.020
Zebrafish
single organism cell adhesion GO:0098602 29 0.020
Zebrafish
regulation of blood circulation GO:1903522 32 0.020
positive regulation of cell motility GO:2000147 11 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.019
regulation of nucleic acid templated transcription GO:1903506 213 0.019
amine metabolic process GO:0009308 2 0.019
larval development GO:0002164 2 0.019
regulation of synaptic plasticity GO:0048167 1 0.019
cellular protein metabolic process GO:0044267 129 0.019
axon extension GO:0048675 45 0.019
regulation of cell growth GO:0001558 29 0.019
regulation of circadian rhythm GO:0042752 4 0.019
regulation of axon guidance GO:1902667 8 0.018
positive regulation of cell cycle GO:0045787 3 0.018
regulation of cytokine production GO:0001817 3 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
immune response GO:0006955 28 0.018
regulation of extent of cell growth GO:0061387 29 0.018
regulation of chemotaxis GO:0050920 18 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.018
homeostatic process GO:0042592 142 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
negative regulation of sequestering of calcium ion GO:0051283 4 0.017
negative regulation of signal transduction GO:0009968 94 0.017
regulation of calcium ion transport GO:0051924 2 0.017
regulation of phosphate metabolic process GO:0019220 43 0.017
positive regulation of epithelial cell differentiation GO:0030858 2 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
i kappab kinase nf kappab signaling GO:0007249 4 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
respiratory system development GO:0060541 5 0.017
energy reserve metabolic process GO:0006112 2 0.017
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.017
cellular response to growth factor stimulus GO:0071363 39 0.017
cellular response to stress GO:0033554 62 0.016
regulation of phosphorylation GO:0042325 26 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
negative regulation of catabolic process GO:0009895 3 0.016
negative regulation of mapk cascade GO:0043409 4 0.016
cilium organization GO:0044782 71 0.016
multicellular organismal macromolecule metabolic process GO:0044259 2 0.016
cell growth GO:0016049 57 0.016
regulation of stem cell differentiation GO:2000736 4 0.016
negative regulation of map kinase activity GO:0043407 2 0.016
regulation of cellular response to growth factor stimulus GO:0090287 35 0.016
macromolecular complex disassembly GO:0032984 1 0.016
positive regulation of locomotion GO:0040017 14 0.016
glial cell proliferation GO:0014009 4 0.016
macromolecular complex subunit organization GO:0043933 74 0.016
Zebrafish
positive regulation of axon guidance GO:1902669 1 0.016
vasculogenesis GO:0001570 41 0.016
negative regulation of response to stimulus GO:0048585 104 0.016
nuclear transport GO:0051169 4 0.015
positive regulation of cell morphogenesis involved in differentiation GO:0010770 6 0.015
regulation of growth GO:0040008 42 0.015
Fly
homeostasis of number of cells GO:0048872 62 0.015
protein import into nucleus GO:0006606 3 0.015
positive regulation of leukocyte mediated immunity GO:0002705 1 0.015
protein targeting to nucleus GO:0044744 3 0.015
positive regulation of blood circulation GO:1903524 2 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
defense response GO:0006952 47 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.015
protein import GO:0017038 3 0.015
ear development GO:0043583 127 0.015
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
phosphatidylinositol mediated signaling GO:0048015 2 0.015
inositol lipid mediated signaling GO:0048017 2 0.014
somatic muscle development GO:0007525 4 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
regulation of molecular function GO:0065009 70 0.014
immunoglobulin mediated immune response GO:0016064 3 0.014
regulation of synapse structure and activity GO:0050803 5 0.014
Fly
multicellular organismal metabolic process GO:0044236 2 0.014
pericardium morphogenesis GO:0003344 1 0.014
signal transduction in absence of ligand GO:0038034 1 0.014
gtp metabolic process GO:0046039 4 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
cellular amine metabolic process GO:0044106 2 0.014
response to biotic stimulus GO:0009607 97 0.014
regulation of cellular protein metabolic process GO:0032268 52 0.014
regulation of jak stat cascade GO:0046425 3 0.014
negative regulation of gene expression GO:0010629 65 0.014
regulation of dendrite development GO:0050773 3 0.014
negative regulation of multicellular organismal process GO:0051241 69 0.014
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 6 0.014
Zebrafish
negative regulation of stem cell differentiation GO:2000737 2 0.014
cell death GO:0008219 121 0.014
negative regulation of response to cytokine stimulus GO:0060761 2 0.014
regulation of protein localization to plasma membrane GO:1903076 1 0.014
positive regulation of protein metabolic process GO:0051247 23 0.014
response to bacterium GO:0009617 58 0.013
positive regulation of cell migration GO:0030335 11 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
establishment of protein localization to organelle GO:0072594 4 0.013
positive regulation of cell proliferation GO:0008284 15 0.013
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.013
positive regulation of cytokine production GO:0001819 2 0.013
negative regulation of secretion GO:0051048 2 0.013
cellular component assembly GO:0022607 170 0.013
Zebrafish Fly
positive regulation of cell differentiation GO:0045597 30 0.013
regulation of multicellular organismal metabolic process GO:0044246 2 0.013
organelle localization GO:0051640 49 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
small gtpase mediated signal transduction GO:0007264 8 0.013
positive regulation of cell development GO:0010720 25 0.013
negative regulation of developmental process GO:0051093 65 0.013
fat soluble vitamin metabolic process GO:0006775 4 0.013
macromolecular complex assembly GO:0065003 35 0.013
Zebrafish
determination of bilateral symmetry GO:0009855 204 0.013
negative regulation of secretion by cell GO:1903531 2 0.013
segmentation GO:0035282 97 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
aorta development GO:0035904 4 0.013
response to drug GO:0042493 3 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
mesenchymal cell development GO:0014031 78 0.012
release of sequestered calcium ion into cytosol GO:0051209 3 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
regulation of neurological system process GO:0031644 2 0.012
negative regulation of growth GO:0045926 10 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
regulation of cytokine mediated signaling pathway GO:0001959 3 0.012
protein dephosphorylation GO:0006470 3 0.012
regulation of protein metabolic process GO:0051246 56 0.012
positive regulation of glucose transport GO:0010828 1 0.012
homeostasis of number of cells within a tissue GO:0048873 4 0.012
post embryonic organ development GO:0048569 4 0.012
connective tissue development GO:0061448 99 0.012
Zebrafish
female gonad development GO:0008585 4 0.012
locomotory behavior GO:0007626 34 0.012
regulation of ossification GO:0030278 5 0.012
positive regulation of neuron death GO:1901216 1 0.012
positive regulation of cell killing GO:0031343 2 0.012
phagocytosis engulfment GO:0006911 1 0.012
regulation of neuronal synaptic plasticity GO:0048168 1 0.012
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.012
establishment of localization in cell GO:0051649 77 0.012
somatic stem cell maintenance GO:0035019 1 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
renal system process involved in regulation of blood volume GO:0001977 1 0.012
positive regulation of neuron differentiation GO:0045666 12 0.012
posterior lateral line system development GO:0048915 46 0.012

bmpr2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.212
cardiovascular system disease DOID:1287 0 0.212
artery disease DOID:0050828 0 0.044
vascular disease DOID:178 0 0.044
heart disease DOID:114 0 0.036
bone disease DOID:0080001 0 0.020
musculoskeletal system disease DOID:17 0 0.020
connective tissue disease DOID:65 0 0.020
hypertension DOID:10763 0 0.015