Danio rerio

0 known processes

brms1

breast cancer metastasis-suppressor 1

(Aliases: MGC56414,wu:fb57b08,si:zc194c5.2,zgc:56414,si:zc188c22.3)

brms1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.117
larval development GO:0002164 2 0.091
cellular macromolecule metabolic process GO:0044260 391 0.077
phagocytosis GO:0006909 3 0.070
organic substance biosynthetic process GO:1901576 289 0.061
maintenance of location GO:0051235 4 0.059
lipid storage GO:0019915 1 0.058
cellular nitrogen compound metabolic process GO:0034641 290 0.058
cellular biosynthetic process GO:0044249 286 0.057
regulation of metabolic process GO:0019222 359 0.054
positive regulation of transport GO:0051050 2 0.050
cellular aromatic compound metabolic process GO:0006725 295 0.049
cell surface receptor signaling pathway GO:0007166 325 0.049
regulation of cellular metabolic process GO:0031323 320 0.048
autophagy GO:0006914 4 0.048
multicellular organism growth GO:0035264 4 0.047
nitrogen compound metabolic process GO:0006807 319 0.046
regulation of multicellular organismal process GO:0051239 277 0.045
locomotion GO:0040011 313 0.045
biosynthetic process GO:0009058 294 0.043
protein secretion GO:0009306 1 0.043
regulation of response to stimulus GO:0048583 269 0.042
organonitrogen compound metabolic process GO:1901564 74 0.042
regulation of biosynthetic process GO:0009889 250 0.039
cellular nitrogen compound biosynthetic process GO:0044271 218 0.038
stem cell proliferation GO:0072089 4 0.038
embryo development ending in birth or egg hatching GO:0009792 271 0.038
regulation of cellular biosynthetic process GO:0031326 245 0.038
protein metabolic process GO:0019538 183 0.038
regulation of establishment of protein localization GO:0070201 4 0.037
response to external stimulus GO:0009605 264 0.037
organic cyclic compound metabolic process GO:1901360 301 0.036
regulation of protein transport GO:0051223 3 0.035
regulation of nitrogen compound metabolic process GO:0051171 251 0.035
heterocycle biosynthetic process GO:0018130 215 0.035
regulation of macromolecule biosynthetic process GO:0010556 225 0.034
embryonic organ development GO:0048568 381 0.034
regulation of stem cell proliferation GO:0072091 2 0.034
nucleobase containing compound biosynthetic process GO:0034654 205 0.033
signal transduction GO:0007165 455 0.033
heterocycle metabolic process GO:0046483 290 0.033
regulation of transcription dna templated GO:0006355 213 0.033
amine metabolic process GO:0009308 2 0.032
single organism metabolic process GO:0044710 217 0.032
regulation of cell communication GO:0010646 232 0.031
tube morphogenesis GO:0035239 349 0.031
cellular response to external stimulus GO:0071496 2 0.031
gene expression GO:0010467 252 0.030
cellular amine metabolic process GO:0044106 2 0.030
cellular carbohydrate metabolic process GO:0044262 4 0.030
regulation of cellular ketone metabolic process GO:0010565 7 0.030
aromatic compound biosynthetic process GO:0019438 217 0.029
positive regulation of cell cycle GO:0045787 3 0.029
negative regulation of biological process GO:0048519 304 0.029
endosomal transport GO:0016197 2 0.028
regulation of rna metabolic process GO:0051252 224 0.028
nucleobase containing compound metabolic process GO:0006139 274 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
cellular ketone metabolic process GO:0042180 11 0.027
positive regulation of biological process GO:0048518 253 0.027
positive regulation of cellular component biogenesis GO:0044089 3 0.027
cellular protein modification process GO:0006464 100 0.027
small molecule metabolic process GO:0044281 77 0.027
microtubule organizing center organization GO:0031023 1 0.027
protein acylation GO:0043543 3 0.026
neuron differentiation GO:0030182 353 0.026
rna biosynthetic process GO:0032774 181 0.026
internal peptidyl lysine acetylation GO:0018393 2 0.026
regulation of organelle assembly GO:1902115 4 0.026
phagocytosis engulfment GO:0006911 1 0.026
regulation of multicellular organism growth GO:0040014 4 0.026
transcription from rna polymerase ii promoter GO:0006366 80 0.026
macromolecule modification GO:0043412 111 0.026
negative regulation of cellular process GO:0048523 283 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
digestive tract development GO:0048565 265 0.025
establishment of protein localization to organelle GO:0072594 4 0.025
establishment of localization GO:0051234 244 0.025
regulation of cell shape GO:0008360 1 0.025
cellular protein metabolic process GO:0044267 129 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
regulation of cell projection assembly GO:0060491 4 0.024
protein acetylation GO:0006473 2 0.024
centrosome organization GO:0051297 1 0.024
embryonic organ morphogenesis GO:0048562 274 0.024
cellular component movement GO:0006928 335 0.024
cellular response to extracellular stimulus GO:0031668 2 0.024
response to stress GO:0006950 263 0.024
protein polymerization GO:0051258 4 0.024
regulation of neural precursor cell proliferation GO:2000177 3 0.024
locomotor rhythm GO:0045475 3 0.024
organelle organization GO:0006996 227 0.024
regulation of reactive oxygen species metabolic process GO:2000377 2 0.024
cellular response to nutrient levels GO:0031669 2 0.023
neuroblast proliferation GO:0007405 2 0.023
immune system process GO:0002376 241 0.023
gastrulation GO:0007369 208 0.023
cytokinesis GO:0000910 3 0.023
extrinsic apoptotic signaling pathway GO:0097191 3 0.023
macromolecule biosynthetic process GO:0009059 227 0.023
regulation of gene expression GO:0010468 265 0.023
regulation of signal transduction GO:0009966 225 0.023
nucleic acid metabolic process GO:0090304 244 0.023
response to drug GO:0042493 3 0.022
regulation of cytokine production GO:0001817 3 0.022
regulation of macromolecule metabolic process GO:0060255 317 0.022
peptidyl lysine acetylation GO:0018394 2 0.022
production of molecular mediator of immune response GO:0002440 2 0.022
cell part morphogenesis GO:0032990 246 0.022
stem cell maintenance GO:0019827 4 0.022
response to chemical GO:0042221 320 0.022
regulation of biological quality GO:0065008 263 0.022
regulation of multicellular organismal development GO:2000026 223 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
phosphorus metabolic process GO:0006793 109 0.021
cell projection morphogenesis GO:0048858 244 0.021
phosphate containing compound metabolic process GO:0006796 108 0.021
regulation of signaling GO:0023051 235 0.021
cell morphogenesis GO:0000902 289 0.021
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.021
rna metabolic process GO:0016070 219 0.021
regulation of primary metabolic process GO:0080090 311 0.021
secondary metabolic process GO:0019748 3 0.021
regulation of nucleic acid templated transcription GO:1903506 213 0.021
regulation of developmental process GO:0050793 247 0.021
kidney development GO:0001822 92 0.021
regulation of synapse organization GO:0050807 3 0.020
cell cycle g2 m phase transition GO:0044839 4 0.020
membrane invagination GO:0010324 1 0.020
regulation of reproductive process GO:2000241 4 0.020
internal protein amino acid acetylation GO:0006475 2 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
nucleic acid templated transcription GO:0097659 181 0.020
leukocyte proliferation GO:0070661 1 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
regulation of binding GO:0051098 3 0.020
digestive system development GO:0055123 289 0.020
heart development GO:0007507 313 0.020
gtp catabolic process GO:0006184 2 0.020
chordate embryonic development GO:0043009 271 0.019
centrosome duplication GO:0051298 1 0.019
positive regulation of map kinase activity GO:0043406 3 0.019
compound eye development GO:0048749 2 0.019
positive regulation of catabolic process GO:0009896 4 0.019
sensory organ development GO:0007423 393 0.019
nuclear transport GO:0051169 4 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.019
regulation of epithelial cell proliferation GO:0050678 3 0.019
generation of neurons GO:0048699 385 0.019
transport GO:0006810 220 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
membrane fusion GO:0061025 2 0.019
protein modification process GO:0036211 100 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
actin filament polymerization GO:0030041 2 0.019
chemosensory behavior GO:0007635 1 0.019
hepaticobiliary system development GO:0061008 98 0.019
guanosine containing compound metabolic process GO:1901068 4 0.018
cellular response to starvation GO:0009267 1 0.018
regulation of cell activation GO:0050865 1 0.018
regulation of production of molecular mediator of immune response GO:0002700 1 0.018
single organism localization GO:1902578 225 0.018
tissue remodeling GO:0048771 4 0.018
gtp metabolic process GO:0046039 4 0.018
eye development GO:0001654 277 0.018
regulation of wound healing GO:0061041 2 0.018
organic acid metabolic process GO:0006082 31 0.018
g2 m transition of mitotic cell cycle GO:0000086 4 0.018
spindle assembly GO:0051225 2 0.018
neuron development GO:0048666 262 0.018
positive regulation of cytoskeleton organization GO:0051495 3 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
transcription dna templated GO:0006351 181 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.018
phagosome maturation GO:0090382 1 0.018
regulation of circadian rhythm GO:0042752 4 0.018
ribosomal small subunit biogenesis GO:0042274 2 0.018
determination of bilateral symmetry GO:0009855 204 0.017
regulation of carbohydrate metabolic process GO:0006109 4 0.017
female sex differentiation GO:0046660 4 0.017
cell projection assembly GO:0030031 64 0.017
positive regulation of stem cell proliferation GO:2000648 1 0.017
negative regulation of response to stimulus GO:0048585 104 0.017
synaptic vesicle localization GO:0097479 1 0.017
meiotic nuclear division GO:0007126 4 0.017
hormone transport GO:0009914 2 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
eye morphogenesis GO:0048592 144 0.017
regulation of jak stat cascade GO:0046425 3 0.017
mitochondrion organization GO:0007005 4 0.017
regulation of synaptic plasticity GO:0048167 1 0.017
cellular amide metabolic process GO:0043603 4 0.016
antimicrobial humoral response GO:0019730 2 0.016
positive regulation of secretion GO:0051047 1 0.016
protein import into nucleus GO:0006606 3 0.016
cellular component disassembly GO:0022411 1 0.016
glycerophospholipid biosynthetic process GO:0046474 1 0.016
protein import GO:0017038 3 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
multi organism process GO:0051704 134 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
spermatid development GO:0007286 2 0.016
positive regulation of cell activation GO:0050867 1 0.016
localization of cell GO:0051674 244 0.016
regulation of protein complex assembly GO:0043254 3 0.016
single organism organelle organization GO:1902589 199 0.016
camera type eye development GO:0043010 222 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
brain development GO:0007420 293 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
nuclear import GO:0051170 3 0.016
specification of symmetry GO:0009799 204 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
translational initiation GO:0006413 3 0.015
liver development GO:0001889 96 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
urogenital system development GO:0001655 97 0.015
single organism membrane fusion GO:0044801 2 0.015
response to hexose GO:0009746 3 0.015
regulation of hormone secretion GO:0046883 2 0.015
regulation of synapse assembly GO:0051963 3 0.015
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.015
activation of mapk activity GO:0000187 3 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
negative regulation of epithelial cell proliferation GO:0050680 1 0.015
regulation of microtubule cytoskeleton organization GO:0070507 3 0.015
lymphocyte proliferation GO:0046651 1 0.015
somatic muscle development GO:0007525 4 0.015
stem cell division GO:0017145 1 0.015
positive regulation of cellular process GO:0048522 201 0.015
protein dephosphorylation GO:0006470 3 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
regulation of protein polymerization GO:0032271 2 0.014
cilium morphogenesis GO:0060271 85 0.014
centrosome cycle GO:0007098 1 0.014
b cell differentiation GO:0030183 1 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
positive regulation of translation GO:0045727 1 0.014
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
positive regulation of metabolic process GO:0009893 108 0.014
cellular component morphogenesis GO:0032989 336 0.014
cellular protein catabolic process GO:0044257 4 0.014
head development GO:0060322 303 0.014
negative regulation of chromosome organization GO:2001251 1 0.014
regulation of cellular component organization GO:0051128 86 0.014
b cell activation GO:0042113 2 0.014
cell projection organization GO:0030030 284 0.014
regulation of blood pressure GO:0008217 1 0.014
single organism transport GO:0044765 206 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
meiotic cell cycle process GO:1903046 3 0.014
glycerolipid biosynthetic process GO:0045017 1 0.014
cellular respiration GO:0045333 3 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
blood circulation GO:0008015 87 0.014
positive regulation of macromolecule metabolic process GO:0010604 93 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
cell aging GO:0007569 2 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
canonical wnt signaling pathway GO:0060070 48 0.014
regulation of ph GO:0006885 3 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.014
peptide metabolic process GO:0006518 1 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
response to monosaccharide GO:0034284 3 0.014
regulation of response to biotic stimulus GO:0002831 2 0.014
oxoacid metabolic process GO:0043436 31 0.014
regulation of chromosome segregation GO:0051983 1 0.014
determination of left right symmetry GO:0007368 179 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
regulation of protein targeting GO:1903533 2 0.013
mononuclear cell proliferation GO:0032943 1 0.013
cell substrate adhesion GO:0031589 4 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
spermatid differentiation GO:0048515 2 0.013
regulation of protein catabolic process GO:0042176 1 0.013
dna templated transcription elongation GO:0006354 3 0.013
taxis GO:0042330 109 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
central nervous system development GO:0007417 387 0.013
adult behavior GO:0030534 2 0.013
negative regulation of protein complex assembly GO:0031333 1 0.013
negative regulation of defense response GO:0031348 2 0.013
growth GO:0040007 174 0.013
negative regulation of developmental process GO:0051093 65 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
cell migration GO:0016477 237 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
response to topologically incorrect protein GO:0035966 2 0.013
regulation of autophagy GO:0010506 3 0.013
regulation of cell development GO:0060284 100 0.013
meiotic chromosome segregation GO:0045132 3 0.013
female gonad development GO:0008585 4 0.013
protein localization to nucleus GO:0034504 3 0.013
dna templated transcription initiation GO:0006352 1 0.013
homeostatic process GO:0042592 142 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
regulation of filopodium assembly GO:0051489 2 0.013
negative regulation of immune response GO:0050777 2 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
blood vessel morphogenesis GO:0048514 216 0.013
vasculature development GO:0001944 278 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
system process GO:0003008 185 0.013
peptidyl threonine modification GO:0018210 1 0.012
skeletal system development GO:0001501 181 0.012
peptide transport GO:0015833 1 0.012
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.012
single fertilization GO:0007338 3 0.012
response to carbohydrate GO:0009743 3 0.012
nuclear envelope organization GO:0006998 2 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.012
cilium assembly GO:0042384 58 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
regulation of blood vessel size GO:0050880 2 0.012
establishment of localization in cell GO:0051649 77 0.012
positive regulation of wound healing GO:0090303 1 0.012
primary neural tube formation GO:0014020 1 0.012
regulation of response to nutrient levels GO:0032107 1 0.012
single organism nuclear import GO:1902593 3 0.012
cellular component biogenesis GO:0044085 178 0.012
protein localization to vacuole GO:0072665 1 0.012
carbohydrate homeostasis GO:0033500 1 0.012
circulatory system process GO:0003013 87 0.012
regulation of response to extracellular stimulus GO:0032104 1 0.012
rna transport GO:0050658 2 0.012
positive regulation of leukocyte differentiation GO:1902107 1 0.012
macroautophagy GO:0016236 1 0.012
lamellipodium assembly GO:0030032 1 0.012
regulation of tube size GO:0035150 2 0.012
regulation of lipase activity GO:0060191 2 0.012
protein localization to plasma membrane GO:0072659 1 0.012
response to hydrogen peroxide GO:0042542 3 0.012
epithelial cell morphogenesis GO:0003382 2 0.012
vacuolar transport GO:0007034 2 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
multi organism cellular process GO:0044764 2 0.012
positive regulation of protein polymerization GO:0032273 2 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
protein targeting to nucleus GO:0044744 3 0.012
regulation of cell substrate adhesion GO:0010810 1 0.012
gland development GO:0048732 143 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
cellular localization GO:0051641 97 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
tube closure GO:0060606 1 0.011
peptidyl serine modification GO:0018209 2 0.011
organic substance transport GO:0071702 58 0.011
macromolecular complex disassembly GO:0032984 1 0.011
neuron projection development GO:0031175 180 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
regulation of nervous system development GO:0051960 90 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
regulation of molecular function GO:0065009 70 0.011
renal system development GO:0072001 94 0.011
muscle cell migration GO:0014812 4 0.011
organelle fusion GO:0048284 3 0.011
interspecies interaction between organisms GO:0044419 4 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
negative regulation of cell communication GO:0010648 96 0.011
negative regulation of kinase activity GO:0033673 4 0.011
developmental growth GO:0048589 166 0.011
lateral inhibition GO:0046331 1 0.011
regulation of jun kinase activity GO:0043506 3 0.011
neurotransmitter secretion GO:0007269 2 0.011
protein complex disassembly GO:0043241 1 0.011
hormone secretion GO:0046879 2 0.011
positive regulation of cytokine production GO:0001819 2 0.011
pronephros development GO:0048793 69 0.011
digestive tract morphogenesis GO:0048546 231 0.011
synaptic vesicle transport GO:0048489 1 0.011
nucleic acid transport GO:0050657 2 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
atp catabolic process GO:0006200 4 0.011
positive regulation of immune effector process GO:0002699 3 0.011
cell cycle arrest GO:0007050 1 0.011
cell motility GO:0048870 244 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
positive regulation of cellular biosynthetic process GO:0031328 68 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
negative regulation of protein transport GO:0051224 3 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
negative regulation of signal transduction GO:0009968 94 0.011
regulation of organ growth GO:0046620 3 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
long chain fatty acid metabolic process GO:0001676 1 0.011
cell proliferation GO:0008283 80 0.011
nuclear export GO:0051168 1 0.011
positive regulation of multi organism process GO:0043902 3 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
lamellipodium organization GO:0097581 1 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
response to uv GO:0009411 3 0.010
cell matrix adhesion GO:0007160 4 0.010
blood vessel development GO:0001568 246 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.010
nephron epithelium morphogenesis GO:0072088 1 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
sleep GO:0030431 1 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
regulation of systemic arterial blood pressure GO:0003073 1 0.010
epithelial cell differentiation GO:0030855 116 0.010
protein modification by small protein removal GO:0070646 1 0.010
organelle assembly GO:0070925 110 0.010
intracellular signal transduction GO:0035556 85 0.010
endocrine process GO:0050886 2 0.010
nucleus organization GO:0006997 7 0.010
regulation of transmembrane transporter activity GO:0022898 2 0.010
glucose homeostasis GO:0042593 1 0.010
regulation of catalytic activity GO:0050790 55 0.010
synaptic vesicle endocytosis GO:0048488 1 0.010

brms1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.022
musculoskeletal system disease DOID:17 0 0.011