Danio rerio

26 known processes

bty

bloodthirsty

bty biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
signal transduction GO:0007165 455 0.375
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.343
digestive tract morphogenesis GO:0048546 231 0.321
regulation of multicellular organismal development GO:2000026 223 0.315
organic cyclic compound metabolic process GO:1901360 301 0.304
organic cyclic compound biosynthetic process GO:1901362 223 0.294
regulation of cellular biosynthetic process GO:0031326 245 0.262
wnt signaling pathway GO:0016055 80 0.255
maintenance of location GO:0051235 4 0.202
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.198
morphogenesis of an epithelium GO:0002009 333 0.178
tube morphogenesis GO:0035239 349 0.172
regulation of canonical wnt signaling pathway GO:0060828 34 0.159
regulation of signal transduction GO:0009966 225 0.156
cellular nitrogen compound metabolic process GO:0034641 290 0.154
regulation of signaling GO:0023051 235 0.143
dorsal ventral pattern formation GO:0009953 125 0.142
regionalization GO:0003002 274 0.130
aromatic compound biosynthetic process GO:0019438 217 0.106
positive regulation of transport GO:0051050 2 0.106
nucleic acid metabolic process GO:0090304 244 0.101
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.097
morphogenesis of an epithelial sheet GO:0002011 49 0.096
cellular nitrogen compound biosynthetic process GO:0044271 218 0.088
regulation of developmental process GO:0050793 247 0.088
gene expression GO:0010467 252 0.085
heterocycle metabolic process GO:0046483 290 0.084
regulation of vasculature development GO:1901342 33 0.083
cellular biosynthetic process GO:0044249 286 0.081
hematopoietic or lymphoid organ development GO:0048534 191 0.080
cellular ketone metabolic process GO:0042180 11 0.078
adherens junction organization GO:0034332 4 0.077
canonical wnt signaling pathway GO:0060070 48 0.077
secondary metabolic process GO:0019748 3 0.075
convergent extension GO:0060026 118 0.072
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.072
regulation of biological quality GO:0065008 263 0.072
cerebellar granular layer formation GO:0021684 3 0.065
angiogenesis GO:0001525 158 0.063
nitrogen compound metabolic process GO:0006807 319 0.063
aging GO:0007568 2 0.060
positive regulation of muscle cell differentiation GO:0051149 1 0.059
organic substance biosynthetic process GO:1901576 289 0.058
rna metabolic process GO:0016070 219 0.056
regulation of wnt signaling pathway GO:0030111 53 0.055
transcription dna templated GO:0006351 181 0.054
bmp signaling pathway GO:0030509 52 0.054
locomotion GO:0040011 313 0.053
regulation of nitrogen compound metabolic process GO:0051171 251 0.052
regulation of transcription dna templated GO:0006355 213 0.051
regulation of bmp signaling pathway GO:0030510 39 0.049
negative regulation of macromolecule metabolic process GO:0010605 76 0.048
macromolecule biosynthetic process GO:0009059 227 0.048
protein import GO:0017038 3 0.047
regulation of cellular metabolic process GO:0031323 320 0.046
regulation of sequestering of calcium ion GO:0051282 4 0.045
i kappab kinase nf kappab signaling GO:0007249 4 0.045
rna biosynthetic process GO:0032774 181 0.045
epiboly GO:0090504 41 0.044
blood vessel morphogenesis GO:0048514 216 0.044
regulation of cell communication GO:0010646 232 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.044
regulation of localization GO:0032879 104 0.041
regulation of cytoplasmic transport GO:1903649 4 0.040
regulation of metabolic process GO:0019222 359 0.040
regulation of protein targeting GO:1903533 2 0.040
cell migration GO:0016477 237 0.039
hepatocyte proliferation GO:0072574 2 0.039
carboxylic acid metabolic process GO:0019752 22 0.038
regulation of nucleocytoplasmic transport GO:0046822 2 0.037
amine metabolic process GO:0009308 2 0.037
regulation of cellular amino acid metabolic process GO:0006521 0 0.036
ubiquitin dependent protein catabolic process GO:0006511 3 0.035
gastrulation with mouth forming second GO:0001702 44 0.035
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.035
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.034
foregut morphogenesis GO:0007440 4 0.034
blood vessel development GO:0001568 246 0.032
nucleobase containing compound metabolic process GO:0006139 274 0.032
regulation of establishment of protein localization GO:0070201 4 0.032
regulation of protein localization to nucleus GO:1900180 2 0.032
regulation of cellular ketone metabolic process GO:0010565 7 0.032
digestive tract development GO:0048565 265 0.032
cellular macromolecule biosynthetic process GO:0034645 224 0.032
cerebellar granular layer development GO:0021681 3 0.032
regulation of extent of cell growth GO:0061387 29 0.032
oocyte maturation GO:0001556 4 0.032
response to other organism GO:0051707 97 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.031
positive regulation of catabolic process GO:0009896 4 0.031
cellular protein catabolic process GO:0044257 4 0.030
phosphorylation GO:0016310 69 0.030
cellular response to chemical stimulus GO:0070887 157 0.030
head development GO:0060322 303 0.030
system process GO:0003008 185 0.029
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.029
protein targeting to nucleus GO:0044744 3 0.029
positive regulation of biological process GO:0048518 253 0.029
oxoacid metabolic process GO:0043436 31 0.029
negative regulation of wnt signaling pathway GO:0030178 30 0.028
negative regulation of signal transduction GO:0009968 94 0.028
positive regulation of cellular process GO:0048522 201 0.028
cerebellar granule cell differentiation GO:0021707 3 0.028
muscle tissue development GO:0060537 110 0.027
regulation of intracellular signal transduction GO:1902531 57 0.027
regulation of angiogenesis GO:0045765 26 0.027
gliogenesis GO:0042063 45 0.027
cellular component movement GO:0006928 335 0.026
neuron differentiation GO:0030182 353 0.026
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.026
actin polymerization or depolymerization GO:0008154 2 0.026
regulation of endopeptidase activity GO:0052548 23 0.026
protein depolymerization GO:0051261 1 0.026
positive regulation of cell activation GO:0050867 1 0.025
regulation of gene expression GO:0010468 265 0.025
gall bladder development GO:0061010 1 0.025
larval development GO:0002164 2 0.025
response to external biotic stimulus GO:0043207 97 0.025
cell surface receptor signaling pathway GO:0007166 325 0.025
regulation of proteolysis GO:0030162 24 0.025
positive regulation of gliogenesis GO:0014015 2 0.024
positive regulation of secretion GO:0051047 1 0.024
regulation of biosynthetic process GO:0009889 250 0.024
protein localization to nucleus GO:0034504 3 0.024
regulation of nervous system development GO:0051960 90 0.024
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 1 0.023
regulation of multicellular organismal process GO:0051239 277 0.023
nucleobase containing compound biosynthetic process GO:0034654 205 0.023
phosphate containing compound metabolic process GO:0006796 108 0.023
biosynthetic process GO:0009058 294 0.023
regulation of programmed cell death GO:0043067 101 0.022
neuroblast fate commitment GO:0014017 1 0.022
positive regulation of exocytosis GO:0045921 1 0.022
heterocycle biosynthetic process GO:0018130 215 0.022
abducens nucleus development GO:0021742 2 0.022
vasculature development GO:0001944 278 0.022
spemann organizer formation GO:0060061 10 0.022
cellular amino acid metabolic process GO:0006520 7 0.021
negative regulation of biological process GO:0048519 304 0.021
response to organic substance GO:0010033 153 0.020
cell projection morphogenesis GO:0048858 244 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
regulation of jak stat cascade GO:0046425 3 0.020
positive regulation of dna metabolic process GO:0051054 1 0.020
protein import into nucleus GO:0006606 3 0.020
cell motility GO:0048870 244 0.020
regulation of establishment of planar polarity GO:0090175 4 0.020
positive regulation of macromolecule metabolic process GO:0010604 93 0.020
embryonic foregut morphogenesis GO:0048617 1 0.020
regulation of protein import into nucleus GO:0042306 2 0.019
otic vesicle development GO:0071599 42 0.019
determination of bilateral symmetry GO:0009855 204 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
cerebellar granular layer morphogenesis GO:0021683 3 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
regulation of cell motility GO:2000145 46 0.018
cerebellar cortex formation GO:0021697 5 0.018
compound eye development GO:0048749 2 0.018
growth GO:0040007 174 0.018
optic placode formation GO:0001743 4 0.018
cell cycle process GO:0022402 53 0.018
single organism metabolic process GO:0044710 217 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
neural plate pattern specification GO:0060896 12 0.018
sequestering of calcium ion GO:0051208 3 0.018
digestive system development GO:0055123 289 0.018
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.018
cell cell signaling GO:0007267 52 0.017
negative regulation of mesodermal cell fate specification GO:0042662 3 0.017
microtubule based process GO:0007017 60 0.017
cardiocyte differentiation GO:0035051 44 0.017
anterior posterior pattern specification GO:0009952 152 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
single organism nuclear import GO:1902593 3 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
positive regulation of rna biosynthetic process GO:1902680 57 0.016
modification dependent macromolecule catabolic process GO:0043632 3 0.016
regulation of anatomical structure size GO:0090066 33 0.016
nuclear import GO:0051170 3 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
hepaticobiliary system development GO:0061008 98 0.015
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.015
cellular macromolecule metabolic process GO:0044260 391 0.015
neuron projection development GO:0031175 180 0.015
positive regulation of wnt signaling pathway GO:0030177 13 0.015
cellular response to reactive oxygen species GO:0034614 2 0.015
dorsal convergence GO:0060030 14 0.015
generation of neurons GO:0048699 385 0.015
regulation of cellular component organization GO:0051128 86 0.015
positive regulation of cellular metabolic process GO:0031325 94 0.015
dorsal ventral axis specification GO:0009950 14 0.015
aminoglycan metabolic process GO:0006022 9 0.015
phagocytosis GO:0006909 3 0.015
phosphorus metabolic process GO:0006793 109 0.015
regulation of intracellular protein transport GO:0033157 3 0.014
regulation of protein catabolic process GO:0042176 1 0.014
regulation of synapse assembly GO:0051963 3 0.014
embryonic neurocranium morphogenesis GO:0048702 15 0.014
multicellular organism growth GO:0035264 4 0.014
male meiosis GO:0007140 2 0.014
neuroblast differentiation GO:0014016 1 0.014
stem cell fate commitment GO:0048865 1 0.014
cell substrate adherens junction assembly GO:0007045 1 0.014
mitochondrion organization GO:0007005 4 0.014
cellular localization GO:0051641 97 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
glial cell differentiation GO:0010001 42 0.014
regulation of exocytosis GO:0017157 1 0.014
dna biosynthetic process GO:0071897 3 0.013
organic acid metabolic process GO:0006082 31 0.013
response to uv GO:0009411 3 0.013
regulation of protein depolymerization GO:1901879 1 0.013
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.013
negative regulation of sequestering of calcium ion GO:0051283 4 0.013
cellular catabolic process GO:0044248 27 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
leukocyte proliferation GO:0070661 1 0.013
small molecule metabolic process GO:0044281 77 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
stem cell proliferation GO:0072089 4 0.013
cellular component disassembly GO:0022411 1 0.013
limbic system development GO:0021761 16 0.013
regulation of cellular component movement GO:0051270 55 0.013
regulation of primary metabolic process GO:0080090 311 0.013
regulation of neuron migration GO:2001222 2 0.013
regulation of cellular response to oxidative stress GO:1900407 2 0.013
embryonic organ morphogenesis GO:0048562 274 0.012
syncytium formation by plasma membrane fusion GO:0000768 12 0.012
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.012
neural tube development GO:0021915 62 0.012
b cell activation GO:0042113 2 0.012
protein localization GO:0008104 40 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
cilium or flagellum dependent cell motility GO:0001539 4 0.012
melanin metabolic process GO:0006582 2 0.012
mononuclear cell proliferation GO:0032943 1 0.012
positive regulation of jak stat cascade GO:0046427 2 0.012
hindbrain development GO:0030902 91 0.012
positive regulation of signaling GO:0023056 56 0.012
neural nucleus development GO:0048857 15 0.012
intracellular receptor signaling pathway GO:0030522 30 0.012
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.012
regulation of neuron projection regeneration GO:0070570 7 0.012
cardiac atrium development GO:0003230 4 0.012
cellular component morphogenesis GO:0032989 336 0.012
protein stabilization GO:0050821 2 0.012
regulation of binding GO:0051098 3 0.012
protein acetylation GO:0006473 2 0.012
positive regulation of neuron projection regeneration GO:0070572 3 0.012
striated muscle tissue development GO:0014706 110 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
positive regulation of transcription dna templated GO:0045893 57 0.012
endodermal cell fate determination GO:0007493 2 0.012
regulation of protein transport GO:0051223 3 0.011
developmental maturation GO:0021700 34 0.011
membrane invagination GO:0010324 1 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
neurotransmitter secretion GO:0007269 2 0.011
chemosensory behavior GO:0007635 1 0.011
regulation of cell migration GO:0030334 40 0.011
protein localization to plasma membrane GO:0072659 1 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
positive regulation of metabolic process GO:0009893 108 0.011
regulation of anterior head development GO:2000742 2 0.011
type b pancreatic cell proliferation GO:0044342 1 0.011
cell cycle g2 m phase transition GO:0044839 4 0.011
mucopolysaccharide metabolic process GO:1903510 2 0.011
connective tissue development GO:0061448 99 0.011
cortical actin cytoskeleton organization GO:0030866 1 0.011
regulation of erythrocyte differentiation GO:0045646 2 0.011
regulation of gene expression epigenetic GO:0040029 11 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.011
positive regulation of protein complex disassembly GO:0043243 1 0.011
cell death GO:0008219 121 0.011
epithelial cell morphogenesis GO:0003382 2 0.011
regulation of oocyte development GO:0060281 3 0.011
regulation of hormone secretion GO:0046883 2 0.011
establishment of apical basal cell polarity GO:0035089 2 0.011
taxis GO:0042330 109 0.011
defense response to fungus GO:0050832 2 0.011
positive regulation of striated muscle cell differentiation GO:0051155 1 0.011
energy reserve metabolic process GO:0006112 2 0.011
sequestering of metal ion GO:0051238 3 0.011
primary neural tube formation GO:0014020 1 0.011
nucleic acid templated transcription GO:0097659 181 0.011
regulation of oxidative stress induced cell death GO:1903201 2 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
pancreas development GO:0031016 84 0.011
negative regulation of transcription dna templated GO:0045892 45 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
liver development GO:0001889 96 0.010
anterior head development GO:0097065 2 0.010
positive regulation of cellular biosynthetic process GO:0031328 68 0.010
negative regulation of cell death GO:0060548 60 0.010
morphogenesis of embryonic epithelium GO:0016331 30 0.010
regulation of cell activation GO:0050865 1 0.010
regulation of microtubule based movement GO:0060632 3 0.010
regulation of response to biotic stimulus GO:0002831 2 0.010
biomineral tissue development GO:0031214 13 0.010
regulation of myelination GO:0031641 1 0.010
response to biotic stimulus GO:0009607 97 0.010
axis elongation involved in somitogenesis GO:0090245 2 0.010
regulation of phosphorus metabolic process GO:0051174 43 0.010
neuronal action potential GO:0019228 18 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
neural plate anterior posterior regionalization GO:0021999 8 0.010
macromolecule modification GO:0043412 111 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
release of sequestered calcium ion into cytosol GO:0051209 3 0.010
macromolecular complex disassembly GO:0032984 1 0.010
regulation of cell differentiation GO:0045595 142 0.010

bty disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.057
disease of anatomical entity DOID:7 0 0.057
sensory system disease DOID:0050155 0 0.014