Danio rerio

0 known processes

c6

complement component 6

(Aliases: MGC64073,zgc:64073)

c6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cellular component biogenesis GO:0044089 3 0.163
positive regulation of cellular catabolic process GO:0031331 3 0.129
response to external stimulus GO:0009605 264 0.089
Mouse
nitrogen compound metabolic process GO:0006807 319 0.081
response to hexose GO:0009746 3 0.078
response to chemical GO:0042221 320 0.075
single organism metabolic process GO:0044710 217 0.075
Mouse
regulation of response to stimulus GO:0048583 269 0.070
Mouse
regulation of signal transduction GO:0009966 225 0.067
regulation of cellular metabolic process GO:0031323 320 0.066
organonitrogen compound metabolic process GO:1901564 74 0.065
regulation of metabolic process GO:0019222 359 0.060
Mouse
regulation of developmental process GO:0050793 247 0.059
Mouse
response to carbohydrate GO:0009743 3 0.056
regulation of multicellular organismal process GO:0051239 277 0.056
Mouse
response to external biotic stimulus GO:0043207 97 0.055
cellular macromolecule metabolic process GO:0044260 391 0.055
signal transduction GO:0007165 455 0.054
positive regulation of transport GO:0051050 2 0.053
protein metabolic process GO:0019538 183 0.052
Mouse
establishment of protein localization to plasma membrane GO:0090002 1 0.051
cellular component morphogenesis GO:0032989 336 0.051
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.051
regulation of binding GO:0051098 3 0.051
response to organic substance GO:0010033 153 0.050
cellular protein catabolic process GO:0044257 4 0.049
positive regulation of catabolic process GO:0009896 4 0.047
positive regulation of cellular process GO:0048522 201 0.047
Rat
response to transition metal nanoparticle GO:1990267 28 0.047
membrane fusion GO:0061025 2 0.047
embryonic organ development GO:0048568 381 0.044
heterocycle metabolic process GO:0046483 290 0.043
response to other organism GO:0051707 97 0.042
multicellular organismal metabolic process GO:0044236 2 0.042
oxoacid metabolic process GO:0043436 31 0.041
cellular response to chemical stimulus GO:0070887 157 0.041
regulation of synapse organization GO:0050807 3 0.040
immune system development GO:0002520 191 0.040
proteasomal protein catabolic process GO:0010498 2 0.040
response to ketone GO:1901654 1 0.039
macromolecule biosynthetic process GO:0009059 227 0.039
small molecule metabolic process GO:0044281 77 0.039
organelle fusion GO:0048284 3 0.037
response to amino acid GO:0043200 2 0.036
angiogenesis GO:0001525 158 0.036
Mouse
protein heterooligomerization GO:0051291 1 0.036
regulation of cell communication GO:0010646 232 0.036
negative regulation of biological process GO:0048519 304 0.035
central nervous system development GO:0007417 387 0.035
immune system process GO:0002376 241 0.035
Mouse
response to corticosteroid GO:0031960 1 0.035
protein import GO:0017038 3 0.035
response to drug GO:0042493 3 0.035
response to lipid GO:0033993 60 0.035
organic cyclic compound metabolic process GO:1901360 301 0.035
cell morphogenesis GO:0000902 289 0.035
regulation of signaling GO:0023051 235 0.035
cellular protein metabolic process GO:0044267 129 0.035
cytokinesis GO:0000910 3 0.034
aging GO:0007568 2 0.034
carboxylic acid metabolic process GO:0019752 22 0.034
cellular response to external stimulus GO:0071496 2 0.034
blood vessel development GO:0001568 246 0.034
Mouse
amine metabolic process GO:0009308 2 0.034
regulation of multicellular organism growth GO:0040014 4 0.034
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.033
intracellular signal transduction GO:0035556 85 0.033
cellular protein modification process GO:0006464 100 0.033
response to monosaccharide GO:0034284 3 0.033
protein localization to plasma membrane GO:0072659 1 0.032
positive regulation of developmental process GO:0051094 50 0.032
Mouse
regulation of molecular function GO:0065009 70 0.032
regulation of purine nucleotide catabolic process GO:0033121 2 0.032
multicellular organism growth GO:0035264 4 0.032
synaptic growth at neuromuscular junction GO:0051124 2 0.032
regulation of nucleotide catabolic process GO:0030811 2 0.032
alpha amino acid metabolic process GO:1901605 3 0.032
proteolysis GO:0006508 38 0.032
cellular amine metabolic process GO:0044106 2 0.032
cellular aromatic compound metabolic process GO:0006725 295 0.031
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.031
secondary metabolic process GO:0019748 3 0.031
response to biotic stimulus GO:0009607 97 0.031
lipid homeostasis GO:0055088 3 0.031
ubiquitin dependent protein catabolic process GO:0006511 3 0.030
cellular amide metabolic process GO:0043603 4 0.030
organic acid metabolic process GO:0006082 31 0.030
guanosine containing compound metabolic process GO:1901068 4 0.030
reactive nitrogen species metabolic process GO:2001057 0 0.030
response to nutrient GO:0007584 3 0.029
response to stress GO:0006950 263 0.029
Mouse
regulation of biosynthetic process GO:0009889 250 0.029
gtp metabolic process GO:0046039 4 0.029
cellular macromolecule biosynthetic process GO:0034645 224 0.029
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.029
regulation of cellular amino acid metabolic process GO:0006521 0 0.029
regulation of synapse assembly GO:0051963 3 0.029
organic substance biosynthetic process GO:1901576 289 0.028
regulation of cellular amine metabolic process GO:0033238 0 0.028
cellular amino acid metabolic process GO:0006520 7 0.028
multi organism process GO:0051704 134 0.028
regulation of gtp catabolic process GO:0033124 2 0.028
protein localization GO:0008104 40 0.028
cellular component movement GO:0006928 335 0.027
establishment of localization GO:0051234 244 0.027
positive regulation of signal transduction GO:0009967 56 0.027
response to endogenous stimulus GO:0009719 83 0.027
biosynthetic process GO:0009058 294 0.027
regulation of cell activation GO:0050865 1 0.027
localization of cell GO:0051674 244 0.027
regulation of neurotransmitter secretion GO:0046928 1 0.027
regulation of macromolecule metabolic process GO:0060255 317 0.026
Mouse
positive regulation of biological process GO:0048518 253 0.026
Mouse Rat
sensory organ development GO:0007423 393 0.026
response to vitamin GO:0033273 3 0.026
stem cell proliferation GO:0072089 4 0.026
regulation of protein complex assembly GO:0043254 3 0.026
actin filament based movement GO:0030048 1 0.026
cellular ketone metabolic process GO:0042180 11 0.025
collagen metabolic process GO:0032963 2 0.025
regulation of primary metabolic process GO:0080090 311 0.025
Mouse
camera type eye development GO:0043010 222 0.025
glucose homeostasis GO:0042593 1 0.025
maintenance of location GO:0051235 4 0.025
response to hormone GO:0009725 48 0.025
leukocyte proliferation GO:0070661 1 0.025
growth GO:0040007 174 0.025
regulation of cell death GO:0010941 103 0.024
Rat
establishment of protein localization to organelle GO:0072594 4 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.024
macromolecule modification GO:0043412 111 0.024
regulation of cytoplasmic transport GO:1903649 4 0.024
regulation of biological quality GO:0065008 263 0.024
positive regulation of molecular function GO:0044093 33 0.024
gtp catabolic process GO:0006184 2 0.023
guanosine containing compound catabolic process GO:1901069 2 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.023
negative regulation of cellular process GO:0048523 283 0.023
positive regulation of cell communication GO:0010647 56 0.023
protein targeting to nucleus GO:0044744 3 0.023
regulation of cellular protein catabolic process GO:1903362 1 0.023
response to steroid hormone GO:0048545 35 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
cellular component assembly GO:0022607 170 0.023
positive regulation of secretion by cell GO:1903532 1 0.023
cell migration GO:0016477 237 0.023
vasculature development GO:0001944 278 0.022
Mouse
phagocytosis GO:0006909 3 0.022
cell substrate adhesion GO:0031589 4 0.022
response to oxygen levels GO:0070482 25 0.022
modification dependent protein catabolic process GO:0019941 3 0.022
apoptotic process GO:0006915 116 0.022
Rat
peptidyl serine modification GO:0018209 2 0.021
positive regulation of response to stimulus GO:0048584 80 0.021
Mouse
actin mediated cell contraction GO:0070252 1 0.021
regulation of cell shape GO:0008360 1 0.021
regulation of intracellular signal transduction GO:1902531 57 0.021
protein import into nucleus GO:0006606 3 0.021
regulation of cell differentiation GO:0045595 142 0.021
regulation of protein transport GO:0051223 3 0.021
cell death GO:0008219 121 0.021
Rat
cellular nitrogen compound biosynthetic process GO:0044271 218 0.021
lipid storage GO:0019915 1 0.021
negative regulation of multicellular organismal process GO:0051241 69 0.020
generation of neurons GO:0048699 385 0.020
positive regulation of secretion GO:0051047 1 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.020
death GO:0016265 121 0.020
Rat
single organism organelle organization GO:1902589 199 0.020
multicellular organismal macromolecule metabolic process GO:0044259 2 0.020
eye morphogenesis GO:0048592 144 0.020
positive regulation of signaling GO:0023056 56 0.020
larval development GO:0002164 2 0.020
neurotransmitter transport GO:0006836 2 0.020
negative regulation of protein kinase activity GO:0006469 4 0.019
response to topologically incorrect protein GO:0035966 2 0.019
regulation of transcription dna templated GO:0006355 213 0.019
peptide transport GO:0015833 1 0.019
regulation of gene expression GO:0010468 265 0.019
Mouse
nucleocytoplasmic transport GO:0006913 4 0.019
cellular biosynthetic process GO:0044249 286 0.019
carbohydrate homeostasis GO:0033500 1 0.019
positive regulation of cytokine production GO:0001819 2 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
regulation of cell development GO:0060284 100 0.019
i kappab kinase nf kappab signaling GO:0007249 4 0.019
purine nucleoside monophosphate catabolic process GO:0009128 4 0.019
cellular modified amino acid metabolic process GO:0006575 3 0.018
sensory organ morphogenesis GO:0090596 200 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
neurotransmitter secretion GO:0007269 2 0.018
positive regulation of gtpase activity GO:0043547 1 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
peptide metabolic process GO:0006518 1 0.018
positive regulation of cell activation GO:0050867 1 0.018
response to glucocorticoid GO:0051384 1 0.018
cell part morphogenesis GO:0032990 246 0.018
protein stabilization GO:0050821 2 0.018
positive regulation of metabolic process GO:0009893 108 0.018
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.018
adult behavior GO:0030534 2 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
melanin metabolic process GO:0006582 2 0.018
single organism transport GO:0044765 206 0.018
cellular component biogenesis GO:0044085 178 0.018
regulation of protein import into nucleus GO:0042306 2 0.017
single organism localization GO:1902578 225 0.017
single organism nuclear import GO:1902593 3 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
liver development GO:0001889 96 0.017
carbohydrate derivative metabolic process GO:1901135 61 0.017
nuclear transport GO:0051169 4 0.017
regulation of gtpase activity GO:0043087 2 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
regulation of catalytic activity GO:0050790 55 0.017
cytoplasm organization GO:0007028 4 0.017
peptidyl serine phosphorylation GO:0018105 1 0.016
regulation of nitrogen compound metabolic process GO:0051171 251 0.016
cellular response to hormone stimulus GO:0032870 39 0.016
modification dependent macromolecule catabolic process GO:0043632 3 0.016
protein modification process GO:0036211 100 0.016
regulation of inflammatory response GO:0050727 2 0.016
Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.016
regulation of neurotransmitter transport GO:0051588 1 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
regulation of locomotion GO:0040012 55 0.016
tissue remodeling GO:0048771 4 0.016
wound healing GO:0042060 90 0.016
response to glucose GO:0009749 3 0.016
regulation of metal ion transport GO:0010959 4 0.015
phosphorus metabolic process GO:0006793 109 0.015
cellular response to nutrient levels GO:0031669 2 0.015
negative regulation of cytoplasmic transport GO:1903650 2 0.015
response to wounding GO:0009611 116 0.015
Mouse
regulation of reproductive process GO:2000241 4 0.015
transcription dna templated GO:0006351 181 0.015
cognition GO:0050890 1 0.015
regulation of wound healing GO:0061041 2 0.015
cellular nitrogen compound metabolic process GO:0034641 290 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
chordate embryonic development GO:0043009 271 0.015
Mouse
cellular response to stress GO:0033554 62 0.015
organelle organization GO:0006996 227 0.015
regulation of programmed cell death GO:0043067 101 0.015
Rat
transport GO:0006810 220 0.015
atp catabolic process GO:0006200 4 0.015
rna biosynthetic process GO:0032774 181 0.015
cell projection morphogenesis GO:0048858 244 0.015
negative regulation of apoptotic process GO:0043066 55 0.015
regulation of cellular component organization GO:0051128 86 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
response to alkaloid GO:0043279 2 0.015
regulation of skeletal muscle tissue development GO:0048641 4 0.015
response to bacterium GO:0009617 58 0.015
positive regulation of cellular metabolic process GO:0031325 94 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
Mouse
regulation of stem cell differentiation GO:2000736 4 0.015
negative regulation of cytokine production GO:0001818 1 0.015
cellular response to organic substance GO:0071310 105 0.014
small gtpase mediated signal transduction GO:0007264 8 0.014
regulation of tube size GO:0035150 2 0.014
long chain fatty acid transport GO:0015909 1 0.014
nuclear import GO:0051170 3 0.014
fatty acid transport GO:0015908 1 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
blood vessel morphogenesis GO:0048514 216 0.014
Mouse
positive regulation of cell adhesion GO:0045785 1 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
eye development GO:0001654 277 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
oxidation reduction process GO:0055114 41 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
positive regulation of gtp catabolic process GO:0033126 1 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
regulation of cytokine production GO:0001817 3 0.014
interspecies interaction between organisms GO:0044419 4 0.014
cellular response to endogenous stimulus GO:0071495 68 0.014
neuroblast proliferation GO:0007405 2 0.014
protein localization to nucleus GO:0034504 3 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
regulation of blood vessel size GO:0050880 2 0.014
negative regulation of defense response GO:0031348 2 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
cytoskeleton dependent cytokinesis GO:0061640 3 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
positive regulation of immune effector process GO:0002699 3 0.013
Mouse
specification of symmetry GO:0009799 204 0.013
macromolecular complex assembly GO:0065003 35 0.013
cell matrix adhesion GO:0007160 4 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
protein secretion GO:0009306 1 0.013
nitric oxide metabolic process GO:0046209 2 0.013
phosphorylation GO:0016310 69 0.013
cell substrate junction assembly GO:0007044 2 0.013
response to hydrogen peroxide GO:0042542 3 0.013
response to decreased oxygen levels GO:0036293 25 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
response to virus GO:0009615 21 0.013
gland development GO:0048732 143 0.013
neuron development GO:0048666 262 0.013
notochord development GO:0030903 54 0.013
head development GO:0060322 303 0.013
digestive tract morphogenesis GO:0048546 231 0.013
meiotic nuclear division GO:0007126 4 0.013
regulation of organ growth GO:0046620 3 0.013
negative regulation of kinase activity GO:0033673 4 0.013
regulation of cellular component movement GO:0051270 55 0.013
regulation of protein targeting GO:1903533 2 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
programmed cell death GO:0012501 119 0.013
Rat
negative regulation of secretion GO:0051048 2 0.013
anterior posterior pattern specification GO:0009952 152 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
stem cell maintenance GO:0019827 4 0.013
mitochondrion organization GO:0007005 4 0.013
cell motility GO:0048870 244 0.012
membrane invagination GO:0010324 1 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
single organism biosynthetic process GO:0044711 71 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
defense response GO:0006952 47 0.012
Mouse
circulatory system process GO:0003013 87 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
nucleic acid templated transcription GO:0097659 181 0.012
glial cell migration GO:0008347 3 0.012
cell projection organization GO:0030030 284 0.012
single organism membrane fusion GO:0044801 2 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
axonogenesis GO:0007409 152 0.012
organic cyclic compound biosynthetic process GO:1901362 223 0.012
axon ensheathment in central nervous system GO:0032291 2 0.012
synaptic transmission cholinergic GO:0007271 4 0.012
system process GO:0003008 185 0.012
regulation of striated muscle contraction GO:0006942 2 0.012
regulation of protein localization to nucleus GO:1900180 2 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
cellular response to organic cyclic compound GO:0071407 38 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
Mouse
regulation of apoptotic process GO:0042981 98 0.011
Rat
regulation of cell projection assembly GO:0060491 4 0.011
action potential GO:0001508 19 0.011
response to hypoxia GO:0001666 25 0.011
beta amyloid metabolic process GO:0050435 1 0.011
digestive tract development GO:0048565 265 0.011
regulation of phosphorus metabolic process GO:0051174 43 0.011
cellular catabolic process GO:0044248 27 0.011
immune effector process GO:0002252 23 0.011
Mouse
regulation of dendrite development GO:0050773 3 0.011
muscle organ development GO:0007517 101 0.011
brain development GO:0007420 293 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
regulation of response to cytokine stimulus GO:0060759 3 0.011
positive regulation of protein kinase b signaling GO:0051897 1 0.011
ras protein signal transduction GO:0007265 7 0.011
developmental growth GO:0048589 166 0.011
nuclear export GO:0051168 1 0.011
regulation of cell morphogenesis GO:0022604 42 0.011
protein activation cascade GO:0072376 6 0.011
Mouse
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.011
hormone secretion GO:0046879 2 0.011
positive regulation of cell cycle GO:0045787 3 0.011
locomotion GO:0040011 313 0.011
response to oxygen containing compound GO:1901700 55 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.011
regulation of protein catabolic process GO:0042176 1 0.011
cytoskeleton organization GO:0007010 96 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
cellular response to oxygen levels GO:0071453 1 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
rna localization GO:0006403 4 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
reactive oxygen species biosynthetic process GO:1903409 1 0.010
positive regulation of synapse assembly GO:0051965 1 0.010
tube morphogenesis GO:0035239 349 0.010
lipid catabolic process GO:0016042 4 0.010
regulation of myotube differentiation GO:0010830 2 0.010
regulation of cytokine mediated signaling pathway GO:0001959 3 0.010
erythrocyte differentiation GO:0030218 54 0.010
extracellular structure organization GO:0043062 27 0.010
negative regulation of cell death GO:0060548 60 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.010
negative regulation of multi organism process GO:0043901 3 0.010
retina morphogenesis in camera type eye GO:0060042 79 0.010
protein complex biogenesis GO:0070271 30 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
regulation of nucleic acid templated transcription GO:1903506 213 0.010
response to nicotine GO:0035094 2 0.010
sensory system development GO:0048880 76 0.010

c6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.013
disease of metabolism DOID:0014667 0 0.012
musculoskeletal system disease DOID:17 0 0.011