Danio rerio

0 known processes

cacnb2b

calcium channel, voltage-dependent, beta 2b

(Aliases: cacnb2a,CACNB2.2,si:dkey-32m20.2,im:7141271)

cacnb2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
signal transduction GO:0007165 455 0.497
morphogenesis of an epithelium GO:0002009 333 0.351
Zebrafish
regulation of metabolic process GO:0019222 359 0.334
cell surface receptor signaling pathway GO:0007166 325 0.322
regulation of cell communication GO:0010646 232 0.246
camera type eye development GO:0043010 222 0.195
regulation of biological quality GO:0065008 263 0.192
sensory organ development GO:0007423 393 0.182
head development GO:0060322 303 0.171
negative regulation of biological process GO:0048519 304 0.162
g protein coupled receptor signaling pathway GO:0007186 74 0.152
heart morphogenesis GO:0003007 156 0.151
brain development GO:0007420 293 0.148
maintenance of location GO:0051235 4 0.137
retina morphogenesis in camera type eye GO:0060042 79 0.130
digestive tract development GO:0048565 265 0.129
Zebrafish
eye development GO:0001654 277 0.127
regulation of signal transduction GO:0009966 225 0.126
regulation of localization GO:0032879 104 0.126
Zebrafish Rat Worm
eye photoreceptor cell differentiation GO:0001754 45 0.126
cation transmembrane transport GO:0098655 65 0.124
Zebrafish Rat
eye photoreceptor cell development GO:0042462 30 0.123
gene expression GO:0010467 252 0.116
gastrulation GO:0007369 208 0.112
Zebrafish
homeostatic process GO:0042592 142 0.112
muscle cell development GO:0055001 115 0.111
determination of heart left right asymmetry GO:0061371 117 0.109
regulation of gene expression GO:0010468 265 0.106
embryonic organ morphogenesis GO:0048562 274 0.105
retina development in camera type eye GO:0060041 146 0.104
response to external stimulus GO:0009605 264 0.103
heterocycle metabolic process GO:0046483 290 0.099
cellular nitrogen compound metabolic process GO:0034641 290 0.097
cellular aromatic compound metabolic process GO:0006725 295 0.097
aromatic compound biosynthetic process GO:0019438 217 0.096
cellular response to chemical stimulus GO:0070887 157 0.094
response to stress GO:0006950 263 0.094
cellular macromolecule biosynthetic process GO:0034645 224 0.091
organic cyclic compound metabolic process GO:1901360 301 0.088
establishment of localization GO:0051234 244 0.088
Zebrafish Rat Worm
negative regulation of cellular process GO:0048523 283 0.087
neurological system process GO:0050877 62 0.086
Mouse
regulation of cellular metabolic process GO:0031323 320 0.085
detection of light stimulus GO:0009583 12 0.085
regulation of dna replication GO:0006275 3 0.084
central nervous system development GO:0007417 387 0.082
nitrogen compound metabolic process GO:0006807 319 0.082
cellular response to light stimulus GO:0071482 4 0.081
determination of bilateral symmetry GO:0009855 204 0.079
skeletal system development GO:0001501 181 0.077
multi organism process GO:0051704 134 0.077
Worm
digestive system development GO:0055123 289 0.075
Zebrafish
heart looping GO:0001947 94 0.073
bmp signaling pathway GO:0030509 52 0.071
aging GO:0007568 2 0.070
apical protein localization GO:0045176 6 0.069
regulation of signaling GO:0023051 235 0.068
response to vitamin GO:0033273 3 0.068
organic substance biosynthetic process GO:1901576 289 0.068
regulation of primary metabolic process GO:0080090 311 0.067
response to vitamin b3 GO:0033552 2 0.067
macromolecule biosynthetic process GO:0009059 227 0.065
regulation of nitrogen compound metabolic process GO:0051171 251 0.064
immune system process GO:0002376 241 0.063
photoreceptor cell differentiation GO:0046530 55 0.060
photoreceptor cell development GO:0042461 40 0.060
organonitrogen compound metabolic process GO:1901564 74 0.057
rhodopsin mediated signaling pathway GO:0016056 1 0.057
erythrocyte homeostasis GO:0034101 55 0.056
neuron development GO:0048666 262 0.055
regulation of cell differentiation GO:0045595 142 0.054
response to steroid hormone GO:0048545 35 0.054
regulation of biosynthetic process GO:0009889 250 0.054
negative regulation of response to stimulus GO:0048585 104 0.053
response to ketone GO:1901654 1 0.053
sensory organ morphogenesis GO:0090596 200 0.052
nucleic acid templated transcription GO:0097659 181 0.051
chemical homeostasis GO:0048878 49 0.050
camera type eye photoreceptor cell differentiation GO:0060219 19 0.050
cellular response to radiation GO:0071478 4 0.048
negative regulation of dna replication GO:0008156 2 0.048
lipid storage GO:0019915 1 0.048
heterocycle biosynthetic process GO:0018130 215 0.047
cellular nitrogen compound biosynthetic process GO:0044271 218 0.046
larval development GO:0002164 2 0.046
regulation of metal ion transport GO:0010959 4 0.046
Worm
rna metabolic process GO:0016070 219 0.046
digestive tract morphogenesis GO:0048546 231 0.046
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.045
tube morphogenesis GO:0035239 349 0.045
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.044
voltage gated calcium channel complex assembly GO:0070978 1 0.044
Zebrafish
response to glucocorticoid GO:0051384 1 0.044
cellular macromolecule metabolic process GO:0044260 391 0.044
retinoic acid receptor signaling pathway GO:0048384 16 0.044
cellular amine metabolic process GO:0044106 2 0.043
nucleobase containing compound metabolic process GO:0006139 274 0.043
neuron neuron synaptic transmission GO:0007270 1 0.043
cell death in response to oxidative stress GO:0036473 2 0.042
locomotion GO:0040011 313 0.042
Worm
embryonic heart tube development GO:0035050 133 0.042
cellular biosynthetic process GO:0044249 286 0.042
long chain fatty acid metabolic process GO:0001676 1 0.042
striated muscle cell differentiation GO:0051146 129 0.042
single organism biosynthetic process GO:0044711 71 0.041
organelle assembly GO:0070925 110 0.041
hindbrain development GO:0030902 91 0.041
response to corticosteroid GO:0031960 1 0.040
embryonic organ development GO:0048568 381 0.040
hematopoietic or lymphoid organ development GO:0048534 191 0.040
nucleic acid metabolic process GO:0090304 244 0.040
biosynthetic process GO:0009058 294 0.039
heart development GO:0007507 313 0.038
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.038
determination of left right symmetry GO:0007368 179 0.038
muscle cell differentiation GO:0042692 139 0.037
multicellular organism growth GO:0035264 4 0.037
regulation of blood vessel size GO:0050880 2 0.037
chordate embryonic development GO:0043009 271 0.037
response to organic substance GO:0010033 153 0.037
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.036
single organism localization GO:1902578 225 0.035
Zebrafish Rat Worm
response to lipid GO:0033993 60 0.035
organic acid metabolic process GO:0006082 31 0.035
light induced release of internally sequestered calcium ion GO:0008377 1 0.035
cell migration GO:0016477 237 0.034
ear development GO:0043583 127 0.034
cilium morphogenesis GO:0060271 85 0.033
myeloid cell homeostasis GO:0002262 56 0.032
stem cell division GO:0017145 1 0.032
adult behavior GO:0030534 2 0.031
response to uv GO:0009411 3 0.031
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.031
detection of abiotic stimulus GO:0009582 24 0.031
single organism metabolic process GO:0044710 217 0.031
inorganic ion transmembrane transport GO:0098660 57 0.031
Zebrafish Rat
neuron differentiation GO:0030182 353 0.030
regulation of rna metabolic process GO:0051252 224 0.030
transport GO:0006810 220 0.030
Zebrafish Rat Worm
growth GO:0040007 174 0.030
transcription dna templated GO:0006351 181 0.030
muscle fiber development GO:0048747 52 0.029
cell part morphogenesis GO:0032990 246 0.029
phagocytosis GO:0006909 3 0.029
regulation of multicellular organism growth GO:0040014 4 0.029
cell motility GO:0048870 244 0.028
regulation of cell activation GO:0050865 1 0.028
very long chain fatty acid biosynthetic process GO:0042761 4 0.028
regulation of binding GO:0051098 3 0.028
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.028
camera type eye morphogenesis GO:0048593 108 0.028
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.028
detection of visible light GO:0009584 12 0.028
skeletal muscle tissue development GO:0007519 67 0.027
regulation of response to stimulus GO:0048583 269 0.027
intracellular receptor signaling pathway GO:0030522 30 0.027
negative regulation of rna metabolic process GO:0051253 48 0.027
transmission of nerve impulse GO:0019226 19 0.027
regulation of transcription dna templated GO:0006355 213 0.027
light adaption GO:0036367 1 0.027
multicellular organismal signaling GO:0035637 22 0.026
response to chemical GO:0042221 320 0.026
regulation of establishment of protein localization GO:0070201 4 0.026
negative regulation of macromolecule metabolic process GO:0010605 76 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.025
phototransduction GO:0007602 2 0.025
guanosine containing compound catabolic process GO:1901069 2 0.025
guanosine containing compound metabolic process GO:1901068 4 0.025
embryo development ending in birth or egg hatching GO:0009792 271 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
localization of cell GO:0051674 244 0.025
embryonic heart tube morphogenesis GO:0003143 108 0.025
carboxylic acid metabolic process GO:0019752 22 0.024
specification of symmetry GO:0009799 204 0.024
gland development GO:0048732 143 0.024
regulation of nucleic acid templated transcription GO:1903506 213 0.024
fin development GO:0033333 77 0.024
eye morphogenesis GO:0048592 144 0.024
retinal cone cell development GO:0046549 8 0.024
protein metabolic process GO:0019538 183 0.024
enzyme linked receptor protein signaling pathway GO:0007167 106 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
negative regulation of dna metabolic process GO:0051053 4 0.023
amine metabolic process GO:0009308 2 0.023
cell matrix adhesion GO:0007160 4 0.023
regulation of bmp signaling pathway GO:0030510 39 0.022
mononuclear cell proliferation GO:0032943 1 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
cellular component assembly involved in morphogenesis GO:0010927 107 0.022
regulation of myotube differentiation GO:0010830 2 0.022
system process GO:0003008 185 0.022
Zebrafish Mouse Worm
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
response to abiotic stimulus GO:0009628 122 0.021
blood vessel development GO:0001568 246 0.021
lymphocyte proliferation GO:0046651 1 0.021
regulation of locomotion GO:0040012 55 0.020
Worm
immune system development GO:0002520 191 0.020
response to light intensity GO:0009642 1 0.020
macromolecule localization GO:0033036 54 0.020
organic cyclic compound biosynthetic process GO:1901362 223 0.020
protein secretion GO:0009306 1 0.020
pronephros development GO:0048793 69 0.020
retina homeostasis GO:0001895 12 0.020
sensory perception of chemical stimulus GO:0007606 3 0.020
cellular response to organic substance GO:0071310 105 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.020
chromosome organization involved in meiosis GO:0070192 1 0.020
cellular response to external stimulus GO:0071496 2 0.019
immune response activating signal transduction GO:0002757 5 0.019
striated muscle cell development GO:0055002 108 0.019
regulation of tube size GO:0035150 2 0.019
single organism transport GO:0044765 206 0.019
Zebrafish Rat Worm
epithelial tube morphogenesis GO:0060562 148 0.019
hindbrain morphogenesis GO:0021575 22 0.019
axon ensheathment GO:0008366 18 0.019
cation homeostasis GO:0055080 33 0.018
multicellular organismal response to stress GO:0033555 2 0.018
rna biosynthetic process GO:0032774 181 0.018
meiotic nuclear division GO:0007126 4 0.018
cellular response to biotic stimulus GO:0071216 3 0.018
chemotaxis GO:0006935 104 0.018
response to retinoic acid GO:0032526 6 0.018
fatty acid elongation unsaturated fatty acid GO:0019368 1 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
generation of neurons GO:0048699 385 0.018
muscle tissue development GO:0060537 110 0.018
organelle organization GO:0006996 227 0.017
negative regulation of metabolic process GO:0009892 86 0.017
membrane invagination GO:0010324 1 0.017
negative regulation of gene expression GO:0010629 65 0.017
cellular response to lipopolysaccharide GO:0071222 3 0.017
response to oxygen containing compound GO:1901700 55 0.017
response to nutrient GO:0007584 3 0.017
detection of external stimulus GO:0009581 24 0.017
cranial nerve development GO:0021545 42 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
regulation of meiotic cell cycle GO:0051445 1 0.017
negative regulation of multicellular organismal process GO:0051241 69 0.017
muscle structure development GO:0061061 196 0.017
reactive oxygen species biosynthetic process GO:1903409 1 0.017
cellular component movement GO:0006928 335 0.016
multicellular organismal water homeostasis GO:0050891 1 0.016
negative regulation of protein transport GO:0051224 3 0.016
positive regulation of locomotion GO:0040017 14 0.016
Worm
regulation of reproductive process GO:2000241 4 0.016
activation of mapk activity GO:0000187 3 0.016
regulation of protein binding GO:0043393 3 0.016
long chain fatty acid biosynthetic process GO:0042759 1 0.016
renal system development GO:0072001 94 0.016
fatty acid biosynthetic process GO:0006633 4 0.016
cellular response to lipid GO:0071396 39 0.016
hemopoiesis GO:0030097 183 0.016
positive regulation of biological process GO:0048518 253 0.016
Worm
alternative mrna splicing via spliceosome GO:0000380 1 0.016
cellular component biogenesis GO:0044085 178 0.016
Zebrafish
negative regulation of signal transduction GO:0009968 94 0.016
mitochondrion organization GO:0007005 4 0.016
very long chain fatty acid metabolic process GO:0000038 4 0.016
negative regulation of biosynthetic process GO:0009890 55 0.015
oxoacid metabolic process GO:0043436 31 0.015
neural retina development GO:0003407 49 0.015
regulation of cellular protein metabolic process GO:0032268 52 0.015
cellular response to nutrient levels GO:0031669 2 0.015
regulation of rho protein signal transduction GO:0035023 2 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.015
regulation of skeletal muscle tissue development GO:0048641 4 0.015
cellular ketone metabolic process GO:0042180 11 0.015
phototransduction visible light GO:0007603 2 0.015
behavior GO:0007610 74 0.015
Worm
gtp metabolic process GO:0046039 4 0.015
gamma aminobutyric acid signaling pathway GO:0007214 1 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
cellular protein modification process GO:0006464 100 0.015
cation transport GO:0006812 81 0.014
Zebrafish Rat Worm
mesenchyme development GO:0060485 127 0.014
ameboidal type cell migration GO:0001667 143 0.014
taxis GO:0042330 109 0.014
skeletal system morphogenesis GO:0048705 102 0.014
b cell activation GO:0042113 2 0.014
positive regulation of transport GO:0051050 2 0.014
gtp catabolic process GO:0006184 2 0.014
endosomal transport GO:0016197 2 0.014
negative regulation of transcription dna templated GO:0045892 45 0.014
liver development GO:0001889 96 0.014
embryonic skeletal system development GO:0048706 97 0.014
regulation of protein transport GO:0051223 3 0.014
superoxide metabolic process GO:0006801 2 0.014
response to endogenous stimulus GO:0009719 83 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
synapsis GO:0007129 1 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
regulation of dendrite development GO:0050773 3 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
actin filament based process GO:0030029 64 0.013
establishment or maintenance of apical basal cell polarity GO:0035088 12 0.013
regulation of calcium ion transport GO:0051924 2 0.013
Worm
regulation of cellular ketone metabolic process GO:0010565 7 0.013
negative regulation of notch signaling pathway GO:0045746 6 0.013
neuronal action potential GO:0019228 18 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.013
water homeostasis GO:0030104 4 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
positive regulation of transcription dna templated GO:0045893 57 0.013
single organism organelle organization GO:1902589 199 0.013
phosphorus metabolic process GO:0006793 109 0.013
regulation of response to oxidative stress GO:1902882 2 0.013
hepaticobiliary system development GO:0061008 98 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
muscle organ development GO:0007517 101 0.013
small molecule metabolic process GO:0044281 77 0.013
regulation of developmental process GO:0050793 247 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
regulation of skeletal muscle fiber development GO:0048742 2 0.013
rhythmic process GO:0048511 21 0.013
urogenital system development GO:0001655 97 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
developmental growth GO:0048589 166 0.013
stem cell proliferation GO:0072089 4 0.013
response to alkaloid GO:0043279 2 0.013
photoreceptor cell maintenance GO:0045494 11 0.012
nerve development GO:0021675 45 0.012
regulation of chemotaxis GO:0050920 18 0.012
positive regulation of cell communication GO:0010647 56 0.012
photoreceptor cell fate commitment GO:0046552 1 0.012
immune response regulating signaling pathway GO:0002764 5 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
glial cell differentiation GO:0010001 42 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
erythrocyte development GO:0048821 24 0.012
fatty acid elongation GO:0030497 1 0.012
ion transport GO:0006811 114 0.012
Zebrafish Rat Worm
protein localization GO:0008104 40 0.012
phagocytosis engulfment GO:0006911 1 0.012
divalent inorganic cation homeostasis GO:0072507 22 0.012
fertilization GO:0009566 3 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
immunoglobulin mediated immune response GO:0016064 3 0.012
cell substrate adhesion GO:0031589 4 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
cell projection organization GO:0030030 284 0.012
nuclear migration GO:0007097 3 0.012
apoptotic process GO:0006915 116 0.012
establishment or maintenance of cell polarity GO:0007163 29 0.012
negative regulation of bmp signaling pathway GO:0030514 13 0.011
positive regulation of cell cycle GO:0045787 3 0.011
cellular localization GO:0051641 97 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
protein modification process GO:0036211 100 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.011
regulation of photoreceptor cell differentiation GO:0046532 2 0.011
appendage development GO:0048736 80 0.011
neuron remodeling GO:0016322 1 0.011
ion transmembrane transport GO:0034220 91 0.011
Zebrafish Rat
dna metabolic process GO:0006259 27 0.011
adherens junction organization GO:0034332 4 0.011
metal ion homeostasis GO:0055065 26 0.011
toll like receptor signaling pathway GO:0002224 4 0.011
negative regulation of defense response GO:0031348 2 0.011
intracellular signal transduction GO:0035556 85 0.011
regulation of protein import into nucleus GO:0042306 2 0.010
striated muscle tissue development GO:0014706 110 0.010
regulation of transmembrane transport GO:0034762 18 0.010
Zebrafish Rat
angiogenesis GO:0001525 158 0.010
locomotor rhythm GO:0045475 3 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
positive regulation of cell activation GO:0050867 1 0.010
reactive oxygen species metabolic process GO:0072593 6 0.010
regulation of cytoplasmic transport GO:1903649 4 0.010
embryonic viscerocranium morphogenesis GO:0048703 52 0.010
response to growth factor GO:0070848 39 0.010
regulation of cellular response to oxidative stress GO:1900407 2 0.010
macromolecule modification GO:0043412 111 0.010
regulation of gtpase activity GO:0043087 2 0.010
pronuclear migration GO:0035046 1 0.010

cacnb2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.098
nervous system disease DOID:863 0 0.098
sensory system disease DOID:0050155 0 0.081
eye and adnexa disease DOID:1492 0 0.081
eye disease DOID:5614 0 0.081
retinal disease DOID:5679 0 0.066
retinal degeneration DOID:8466 0 0.060
retinitis pigmentosa DOID:10584 0 0.019