Danio rerio

26 known processes

cacnb4a

calcium channel, voltage-dependent, beta 4a subunit

(Aliases: cacnb4.2)

cacnb4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heart development GO:0007507 313 0.872
heart morphogenesis GO:0003007 156 0.806
muscle cell differentiation GO:0042692 139 0.780
Mouse
striated muscle cell differentiation GO:0051146 129 0.633
Mouse
digestive tract development GO:0048565 265 0.603
metal ion transport GO:0030001 58 0.570
Zebrafish Mouse Worm
heart looping GO:0001947 94 0.529
amino acid transport GO:0006865 2 0.498
Mouse
establishment of localization GO:0051234 244 0.490
Zebrafish Mouse Worm
cellular component morphogenesis GO:0032989 336 0.488
neuron differentiation GO:0030182 353 0.481
muscle cell development GO:0055001 115 0.457
Mouse
single organism transport GO:0044765 206 0.421
Zebrafish Mouse Worm
muscle structure development GO:0061061 196 0.421
Mouse
tube morphogenesis GO:0035239 349 0.399
epithelial tube morphogenesis GO:0060562 148 0.392
signal transduction GO:0007165 455 0.384
Mouse
generation of neurons GO:0048699 385 0.370
organophosphate metabolic process GO:0019637 37 0.367
Mouse
embryonic heart tube morphogenesis GO:0003143 108 0.360
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.358
gamma aminobutyric acid signaling pathway GO:0007214 1 0.347
Mouse
determination of bilateral symmetry GO:0009855 204 0.320
digestive system development GO:0055123 289 0.303
activation of immune response GO:0002253 9 0.300
Mouse
morphogenesis of an epithelium GO:0002009 333 0.299
cation transport GO:0006812 81 0.298
Zebrafish Mouse Worm
regulation of synapse assembly GO:0051963 3 0.286
camp metabolic process GO:0046058 11 0.279
Mouse
heterocycle metabolic process GO:0046483 290 0.265
Mouse
regulation of transport GO:0051049 45 0.263
Zebrafish Mouse Worm
organic cyclic compound metabolic process GO:1901360 301 0.260
Mouse
purine nucleotide metabolic process GO:0006163 27 0.259
Mouse
striated muscle cell development GO:0055002 108 0.239
Mouse
cyclic nucleotide metabolic process GO:0009187 18 0.239
Mouse
determination of heart left right asymmetry GO:0061371 117 0.234
neuron development GO:0048666 262 0.234
digestive tract morphogenesis GO:0048546 231 0.231
specification of symmetry GO:0009799 204 0.229
transmembrane transport GO:0055085 120 0.218
Zebrafish Mouse
blood vessel morphogenesis GO:0048514 216 0.218
regulation of localization GO:0032879 104 0.212
Zebrafish Mouse Worm
embryonic heart tube development GO:0035050 133 0.202
metal ion homeostasis GO:0055065 26 0.200
Mouse
sensory organ morphogenesis GO:0090596 200 0.200
regulation of metal ion transport GO:0010959 4 0.195
Worm
determination of left right symmetry GO:0007368 179 0.190
regulation of signaling GO:0023051 235 0.179
eye development GO:0001654 277 0.163
cellular chemical homeostasis GO:0055082 17 0.161
Mouse
chordate embryonic development GO:0043009 271 0.155
transport GO:0006810 220 0.150
Zebrafish Mouse Worm
cellular aromatic compound metabolic process GO:0006725 295 0.145
Mouse
brain development GO:0007420 293 0.145
inorganic cation transmembrane transport GO:0098662 50 0.144
Zebrafish Mouse
regulation of gene expression GO:0010468 265 0.143
detection of external stimulus GO:0009581 24 0.140
Mouse
nitrogen compound metabolic process GO:0006807 319 0.135
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.135
Mouse
stem cell differentiation GO:0048863 117 0.135
camera type eye photoreceptor cell differentiation GO:0060219 19 0.134
cellular calcium ion homeostasis GO:0006874 13 0.127
Mouse
negative regulation of cell communication GO:0010648 96 0.124
cell morphogenesis involved in differentiation GO:0000904 195 0.123
cell surface receptor signaling pathway GO:0007166 325 0.121
Mouse
purine containing compound metabolic process GO:0072521 29 0.121
Mouse
detection of stimulus involved in sensory perception GO:0050906 21 0.120
Mouse
maintenance of location GO:0051235 4 0.118
small molecule metabolic process GO:0044281 77 0.118
Mouse
locomotion GO:0040011 313 0.117
Worm
aromatic compound biosynthetic process GO:0019438 217 0.115
cation homeostasis GO:0055080 33 0.113
Mouse
organic substance biosynthetic process GO:1901576 289 0.111
detection of abiotic stimulus GO:0009582 24 0.111
Mouse
head development GO:0060322 303 0.108
visual perception GO:0007601 17 0.108
Mouse
regulation of signal transduction GO:0009966 225 0.108
retina morphogenesis in camera type eye GO:0060042 79 0.107
somatic muscle development GO:0007525 4 0.107
cellular localization GO:0051641 97 0.104
nucleobase containing compound metabolic process GO:0006139 274 0.104
Mouse
response to external stimulus GO:0009605 264 0.103
Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.101
immunoglobulin mediated immune response GO:0016064 3 0.101
larval development GO:0002164 2 0.100
embryonic organ morphogenesis GO:0048562 274 0.099
cellular biosynthetic process GO:0044249 286 0.097
nucleotide metabolic process GO:0009117 28 0.097
Mouse
retina development in camera type eye GO:0060041 146 0.094
embryonic organ development GO:0048568 381 0.093
regulation of response to stimulus GO:0048583 269 0.093
Mouse
camera type eye development GO:0043010 222 0.093
neuron projection development GO:0031175 180 0.092
cardiac muscle tissue development GO:0048738 48 0.092
cell migration involved in gastrulation GO:0042074 79 0.089
regulation of rna metabolic process GO:0051252 224 0.089
nucleic acid metabolic process GO:0090304 244 0.089
negative regulation of wnt signaling pathway GO:0030178 30 0.089
cell part morphogenesis GO:0032990 246 0.088
nucleic acid templated transcription GO:0097659 181 0.087
regulation of cell communication GO:0010646 232 0.087
single organism localization GO:1902578 225 0.087
Zebrafish Mouse Worm
regulation of cellular metabolic process GO:0031323 320 0.085
positive regulation of transport GO:0051050 2 0.083
transcription dna templated GO:0006351 181 0.083
regulation of calcium ion transport GO:0051924 2 0.083
Worm
detection of visible light GO:0009584 12 0.081
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.080
gastrulation GO:0007369 208 0.078
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.078
regulation of macromolecule metabolic process GO:0060255 317 0.078
sensory organ development GO:0007423 393 0.077
adult behavior GO:0030534 2 0.076
Mouse
gene expression GO:0010467 252 0.075
cellular metal ion homeostasis GO:0006875 16 0.075
Mouse
positive regulation of biological process GO:0048518 253 0.074
Mouse Worm
calcium ion homeostasis GO:0055074 19 0.072
Mouse
synaptic growth at neuromuscular junction GO:0051124 2 0.071
divalent inorganic cation transport GO:0072511 21 0.070
Zebrafish Mouse Worm
glucose homeostasis GO:0042593 1 0.068
organonitrogen compound metabolic process GO:1901564 74 0.067
Mouse
striated muscle tissue development GO:0014706 110 0.066
ribose phosphate metabolic process GO:0019693 27 0.065
Mouse
biosynthetic process GO:0009058 294 0.064
cell projection morphogenesis GO:0048858 244 0.063
calcium ion import GO:0070509 4 0.063
gastrulation with mouth forming second GO:0001702 44 0.061
convergent extension GO:0060026 118 0.060
hematopoietic or lymphoid organ development GO:0048534 191 0.060
Mouse
germ line stem cell maintenance GO:0030718 2 0.059
calcium ion transport GO:0006816 18 0.059
Zebrafish Mouse Worm
regulation of nitrogen compound metabolic process GO:0051171 251 0.059
organelle assembly GO:0070925 110 0.058
regulation of biosynthetic process GO:0009889 250 0.056
axonogenesis GO:0007409 152 0.056
phosphate containing compound metabolic process GO:0006796 108 0.056
Mouse
muscle fiber development GO:0048747 52 0.055
Mouse
hard palate development GO:0060022 4 0.055
neuron projection morphogenesis GO:0048812 161 0.054
cell projection organization GO:0030030 284 0.054
immune response regulating signaling pathway GO:0002764 5 0.053
Mouse
purine ribonucleotide metabolic process GO:0009150 27 0.053
Mouse
response to lipid GO:0033993 60 0.053
calcium ion transmembrane transport GO:0070588 13 0.053
Zebrafish Mouse
regulation of synapse organization GO:0050807 3 0.052
protein complex biogenesis GO:0070271 30 0.051
Zebrafish
regulation of oocyte development GO:0060281 3 0.050
cellular macromolecule metabolic process GO:0044260 391 0.050
regulation of cell development GO:0060284 100 0.050
response to abiotic stimulus GO:0009628 122 0.049
Mouse
gland development GO:0048732 143 0.047
Mouse
lipid storage GO:0019915 1 0.047
cellular component assembly GO:0022607 170 0.047
Zebrafish
system process GO:0003008 185 0.047
Zebrafish Mouse Worm
response to light stimulus GO:0009416 46 0.047
Mouse
g protein coupled receptor signaling pathway GO:0007186 74 0.046
Mouse
single organism metabolic process GO:0044710 217 0.046
Mouse
positive regulation of reproductive process GO:2000243 2 0.046
multicellular organismal reproductive process GO:0048609 35 0.045
Worm
cell migration GO:0016477 237 0.044
cellular component movement GO:0006928 335 0.044
ion transmembrane transport GO:0034220 91 0.044
Zebrafish Mouse
negative regulation of cellular process GO:0048523 283 0.044
eye morphogenesis GO:0048592 144 0.043
ribonucleotide metabolic process GO:0009259 27 0.043
Mouse
response to oxygen containing compound GO:1901700 55 0.042
regulation of metabolic process GO:0019222 359 0.042
cell morphogenesis GO:0000902 289 0.041
inorganic ion transmembrane transport GO:0098660 57 0.041
Zebrafish Mouse
cardiac muscle cell differentiation GO:0055007 30 0.041
detection of light stimulus GO:0009583 12 0.040
Mouse
rna biosynthetic process GO:0032774 181 0.040
negative regulation of response to stimulus GO:0048585 104 0.039
response to alkaloid GO:0043279 2 0.039
muscle system process GO:0003012 20 0.039
Zebrafish Worm
wnt signaling pathway GO:0016055 80 0.038
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.038
blood vessel development GO:0001568 246 0.038
ameboidal type cell migration GO:0001667 143 0.037
morphogenesis of an epithelial sheet GO:0002011 49 0.037
response to radiation GO:0009314 51 0.037
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.036
protein import GO:0017038 3 0.035
regulation of rna biosynthetic process GO:2001141 213 0.034
muscle tissue development GO:0060537 110 0.034
carbohydrate derivative metabolic process GO:1901135 61 0.034
Mouse
aging GO:0007568 2 0.033
organic cyclic compound biosynthetic process GO:1901362 223 0.032
regulation of ion transmembrane transport GO:0034765 18 0.032
Zebrafish Mouse
positive regulation of oocyte development GO:0060282 1 0.032
ear development GO:0043583 127 0.032
regulation of primary metabolic process GO:0080090 311 0.032
regulation of dendrite development GO:0050773 3 0.031
cellular protein complex assembly GO:0043623 19 0.031
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.031
negative regulation of muscle tissue development GO:1901862 2 0.031
regulation of cardiac muscle cell differentiation GO:2000725 1 0.031
multicellular organismal signaling GO:0035637 22 0.030
Mouse
regulation of nervous system development GO:0051960 90 0.029
eye photoreceptor cell differentiation GO:0001754 45 0.029
mesoderm development GO:0007498 88 0.029
anion transport GO:0006820 38 0.029
Mouse
multi organism process GO:0051704 134 0.028
Worm
organic substance transport GO:0071702 58 0.028
Mouse
ion transport GO:0006811 114 0.028
Zebrafish Mouse Worm
transmission of nerve impulse GO:0019226 19 0.028
Mouse
ear morphogenesis GO:0042471 64 0.027
response to bacterium GO:0009617 58 0.027
axon development GO:0061564 166 0.027
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.027
stem cell fate commitment GO:0048865 1 0.027
regulation of transcription dna templated GO:0006355 213 0.027
vasculature development GO:0001944 278 0.027
regulation of endocytosis GO:0030100 7 0.026
negative regulation of protein complex assembly GO:0031333 1 0.026
regulation of nucleoside metabolic process GO:0009118 2 0.025
regulation of cardiac muscle tissue development GO:0055024 1 0.025
response to vitamin b3 GO:0033552 2 0.025
determination of dorsal ventral asymmetry GO:0048262 34 0.025
synaptic transmission GO:0007268 35 0.025
Mouse
nuclear transport GO:0051169 4 0.025
cellular component biogenesis GO:0044085 178 0.025
Zebrafish
response to chemical GO:0042221 320 0.025
stem cell maintenance GO:0019827 4 0.024
thymus development GO:0048538 10 0.024
Mouse
regulation of sequestering of calcium ion GO:0051282 4 0.024
negative regulation of signaling GO:0023057 96 0.024
cytoskeleton organization GO:0007010 96 0.024
cellular component assembly involved in morphogenesis GO:0010927 107 0.024
regulation of purine nucleotide catabolic process GO:0033121 2 0.023
regulation of canonical wnt signaling pathway GO:0060828 34 0.023
regulation of macromolecule biosynthetic process GO:0010556 225 0.023
regulation of transmembrane transport GO:0034762 18 0.023
Zebrafish Mouse
central nervous system development GO:0007417 387 0.023
reactive oxygen species biosynthetic process GO:1903409 1 0.022
notochord development GO:0030903 54 0.022
forebrain development GO:0030900 96 0.022
cellular cation homeostasis GO:0030003 17 0.022
Mouse
hindbrain development GO:0030902 91 0.022
cardiac conduction system development GO:0003161 1 0.022
small molecule catabolic process GO:0044282 3 0.022
diencephalon development GO:0021536 58 0.022
convergent extension involved in gastrulation GO:0060027 71 0.022
camera type eye morphogenesis GO:0048593 108 0.022
cellular response to lipid GO:0071396 39 0.021
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.021
regulation of protein complex assembly GO:0043254 3 0.021
alpha amino acid metabolic process GO:1901605 3 0.021
regionalization GO:0003002 274 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
guanosine containing compound metabolic process GO:1901068 4 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
positive regulation of secretion by cell GO:1903532 1 0.020
rna metabolic process GO:0016070 219 0.020
hormone transport GO:0009914 2 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.020
cell death in response to oxidative stress GO:0036473 2 0.020
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.020
heart process GO:0003015 71 0.020
negative regulation of striated muscle tissue development GO:0045843 2 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
neuron neuron synaptic transmission GO:0007270 1 0.019
Mouse
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.019
epiboly GO:0090504 41 0.019
response to nutrient GO:0007584 3 0.019
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.019
immune system development GO:0002520 191 0.019
Mouse
cellular amine metabolic process GO:0044106 2 0.019
organic acid catabolic process GO:0016054 3 0.019
digestive tract mesoderm development GO:0007502 1 0.018
lipid metabolic process GO:0006629 52 0.018
glial cell migration GO:0008347 3 0.018
regulation of meiotic cell cycle GO:0051445 1 0.018
morphogenesis of an epithelial fold GO:0060571 1 0.018
detection of light stimulus involved in sensory perception GO:0050962 7 0.018
Mouse
amine metabolic process GO:0009308 2 0.018
organelle organization GO:0006996 227 0.018
response to glucocorticoid GO:0051384 1 0.018
organic acid metabolic process GO:0006082 31 0.017
carboxylic acid catabolic process GO:0046395 3 0.017
peptidyl threonine modification GO:0018210 1 0.017
enzyme linked receptor protein signaling pathway GO:0007167 106 0.017
water homeostasis GO:0030104 4 0.017
angiogenesis GO:0001525 158 0.017
regulation of locomotion GO:0040012 55 0.017
Worm
chemotaxis GO:0006935 104 0.017
positive regulation of cell cycle GO:0045787 3 0.016
immune system process GO:0002376 241 0.016
Mouse
regulation of membrane potential GO:0042391 23 0.016
Mouse
atrial cardiac muscle cell development GO:0055014 4 0.016
chemosensory behavior GO:0007635 1 0.016
regulation of developmental process GO:0050793 247 0.016
divalent metal ion transport GO:0070838 20 0.016
Zebrafish Mouse Worm
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
heart contraction GO:0060047 71 0.015
sensory perception GO:0007600 39 0.015
Mouse
response to corticosteroid GO:0031960 1 0.015
negative regulation of signal transduction GO:0009968 94 0.015
monocarboxylic acid transport GO:0015718 5 0.015
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.015
b cell mediated immunity GO:0019724 3 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
photoreceptor cell differentiation GO:0046530 55 0.015
regulation of reproductive process GO:2000241 4 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
blood circulation GO:0008015 87 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.015
establishment of spindle localization GO:0051293 12 0.015
negative regulation of nuclear division GO:0051784 3 0.015
positive regulation of cellular process GO:0048522 201 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
bmp signaling pathway GO:0030509 52 0.014
chemical homeostasis GO:0048878 49 0.014
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
atrial ventricular junction remodeling GO:0003294 2 0.014
positive regulation of dna metabolic process GO:0051054 1 0.013
heart field specification GO:0003128 1 0.013
multicellular organismal water homeostasis GO:0050891 1 0.013
positive regulation of muscle organ development GO:0048636 1 0.013
response to glucose GO:0009749 3 0.013
interaction with host GO:0051701 4 0.013
gtp metabolic process GO:0046039 4 0.013
negative regulation of developmental process GO:0051093 65 0.013
axon guidance GO:0007411 86 0.013
growth GO:0040007 174 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
neurotransmitter secretion GO:0007269 2 0.012
phosphorus metabolic process GO:0006793 109 0.012
Mouse
regulation of myotube differentiation GO:0010830 2 0.012
hormone secretion GO:0046879 2 0.012
synapse organization GO:0050808 21 0.012
Mouse
canonical wnt signaling pathway GO:0060070 48 0.012
sensory perception of light stimulus GO:0050953 19 0.012
Mouse
cellular homeostasis GO:0019725 26 0.012
Mouse
cell migration involved in heart development GO:0060973 22 0.012
cardiac cell fate commitment GO:0060911 1 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
nitric oxide metabolic process GO:0046209 2 0.012
cell matrix adhesion GO:0007160 4 0.012
regulation of phosphorus metabolic process GO:0051174 43 0.011
nitric oxide biosynthetic process GO:0006809 2 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
cardiac muscle cell development GO:0055013 20 0.011
regulation of system process GO:0044057 40 0.011
behavior GO:0007610 74 0.011
Mouse Worm
mitotic cell cycle process GO:1903047 48 0.011
oxoacid metabolic process GO:0043436 31 0.011
protein complex subunit organization GO:0071822 46 0.011
Zebrafish
cellular ketone metabolic process GO:0042180 11 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
establishment of localization in cell GO:0051649 77 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
regulation of cellular component movement GO:0051270 55 0.011
photoreceptor cell fate commitment GO:0046552 1 0.011
photoreceptor cell development GO:0042461 40 0.011
positive regulation of muscle tissue development GO:1901863 1 0.011
inner ear development GO:0048839 126 0.011
stem cell proliferation GO:0072089 4 0.011
sodium ion transmembrane transport GO:0035725 21 0.011
regulation of response to oxidative stress GO:1902882 2 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
regulation of organ growth GO:0046620 3 0.011
pancreas development GO:0031016 84 0.011
detection of stimulus GO:0051606 29 0.011
Mouse
regulation of muscle organ development GO:0048634 9 0.011
positive regulation of cell proliferation GO:0008284 15 0.011
protein metabolic process GO:0019538 183 0.011
regulation of protein import into nucleus GO:0042306 2 0.010
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.010
cell cycle process GO:0022402 53 0.010
multi organism reproductive process GO:0044703 36 0.010
Worm
hypothalamus development GO:0021854 14 0.010
regulation of skeletal muscle tissue development GO:0048641 4 0.010
organic acid transport GO:0015849 9 0.010
Mouse
cell motility GO:0048870 244 0.010
response to endogenous stimulus GO:0009719 83 0.010
negative regulation of growth rate GO:0045967 1 0.010
axis specification GO:0009798 43 0.010
regulation of hormone secretion GO:0046883 2 0.010

cacnb4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.019
disease of anatomical entity DOID:7 0 0.019