Danio rerio

0 known processes

calb2b

calbindin 2b, (calretinin)

(Aliases: MGC73099,zgc:73099,calb2,wu:fq17g09)

calb2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleobase containing compound metabolic process GO:0006139 274 0.567
central nervous system development GO:0007417 387 0.527
nitrogen compound metabolic process GO:0006807 319 0.450
head development GO:0060322 303 0.433
response to external stimulus GO:0009605 264 0.432
establishment of blood brain barrier GO:0060856 2 0.372
neuroblast proliferation GO:0007405 2 0.367
cell projection organization GO:0030030 284 0.357
multicellular organismal signaling GO:0035637 22 0.335
negative regulation of cell cell adhesion mediated by cadherin GO:2000048 2 0.329
organic cyclic compound metabolic process GO:1901360 301 0.319
cellular cation homeostasis GO:0030003 17 0.296
Rat
regulation of primary metabolic process GO:0080090 311 0.291
metal ion homeostasis GO:0055065 26 0.287
Rat
sensory organ development GO:0007423 393 0.270
cellular nitrogen compound metabolic process GO:0034641 290 0.261
brain development GO:0007420 293 0.235
cellular aromatic compound metabolic process GO:0006725 295 0.234
spindle localization GO:0051653 12 0.215
negative regulation of biological process GO:0048519 304 0.210
larval development GO:0002164 2 0.204
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.199
heterocycle metabolic process GO:0046483 290 0.188
regulation of hydrolase activity GO:0051336 28 0.180
response to chemical GO:0042221 320 0.169
cellular ion homeostasis GO:0006873 17 0.167
Rat
epithelial cell differentiation GO:0030855 116 0.156
small molecule metabolic process GO:0044281 77 0.156
cation homeostasis GO:0055080 33 0.151
Rat
transmission of nerve impulse GO:0019226 19 0.149
stem cell division GO:0017145 1 0.147
developmental growth involved in morphogenesis GO:0060560 86 0.132
localization of cell GO:0051674 244 0.119
cell migration GO:0016477 237 0.114
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.113
locomotion GO:0040011 313 0.110
stem cell proliferation GO:0072089 4 0.110
cellular component movement GO:0006928 335 0.107
cell motility GO:0048870 244 0.105
regulation of anatomical structure morphogenesis GO:0022603 130 0.101
multicellular organismal water homeostasis GO:0050891 1 0.097
cell morphogenesis GO:0000902 289 0.094
regulation of metal ion transport GO:0010959 4 0.094
homeostatic process GO:0042592 142 0.094
Rat
specification of axis polarity GO:0065001 4 0.089
cation transmembrane transport GO:0098655 65 0.086
establishment of localization in cell GO:0051649 77 0.083
specification of organ axis polarity GO:0010084 2 0.083
gene expression GO:0010467 252 0.082
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.080
action potential GO:0001508 19 0.080
cellular localization GO:0051641 97 0.079
eye development GO:0001654 277 0.078
chordate embryonic development GO:0043009 271 0.076
intracellular estrogen receptor signaling pathway GO:0030520 3 0.076
regulation of gene expression GO:0010468 265 0.075
regulation of multicellular organismal development GO:2000026 223 0.073
axon ensheathment in central nervous system GO:0032291 2 0.072
cell cell junction assembly GO:0007043 5 0.072
establishment of localization GO:0051234 244 0.072
membrane fusion GO:0061025 2 0.069
establishment of endothelial blood brain barrier GO:0014045 2 0.068
apical junction assembly GO:0043297 1 0.068
regulation of protein transport GO:0051223 3 0.067
single organism cellular localization GO:1902580 46 0.065
phagocytosis GO:0006909 3 0.065
purine nucleotide metabolic process GO:0006163 27 0.063
signal transduction GO:0007165 455 0.061
regulation of catalytic activity GO:0050790 55 0.060
regulation of developmental process GO:0050793 247 0.058
cellular divalent inorganic cation homeostasis GO:0072503 13 0.058
Rat
cellular macromolecule localization GO:0070727 21 0.057
inorganic cation transmembrane transport GO:0098662 50 0.054
taxis GO:0042330 109 0.052
chemosensory behavior GO:0007635 1 0.050
sensory organ morphogenesis GO:0090596 200 0.050
regulation of cell differentiation GO:0045595 142 0.050
lateral line development GO:0048882 66 0.049
sodium ion homeostasis GO:0055078 3 0.049
cation transport GO:0006812 81 0.048
gabaergic neuron differentiation GO:0097154 2 0.048
behavior GO:0007610 74 0.047
organonitrogen compound metabolic process GO:1901564 74 0.046
positive regulation of camp metabolic process GO:0030816 2 0.046
regulation of rna metabolic process GO:0051252 224 0.046
axon development GO:0061564 166 0.046
morphogenesis of an epithelium GO:0002009 333 0.045
nuclear export GO:0051168 1 0.044
taurine metabolic process GO:0019530 1 0.044
calcium mediated signaling GO:0019722 2 0.044
ribonucleotide metabolic process GO:0009259 27 0.044
gtp catabolic process GO:0006184 2 0.043
nucleotide metabolic process GO:0009117 28 0.043
system process GO:0003008 185 0.043
regulation of nitrogen compound metabolic process GO:0051171 251 0.043
muscle organ development GO:0007517 101 0.042
blood vessel development GO:0001568 246 0.042
sensory system development GO:0048880 76 0.041
endocardium morphogenesis GO:0003160 4 0.041
sensory perception GO:0007600 39 0.041
establishment of endothelial barrier GO:0061028 3 0.040
heterocycle catabolic process GO:0046700 15 0.040
neuron projection regeneration GO:0031102 16 0.040
metal ion transport GO:0030001 58 0.039
organophosphate metabolic process GO:0019637 37 0.039
sodium ion transport GO:0006814 24 0.038
neuronal action potential GO:0019228 18 0.038
regulation of neuronal synaptic plasticity GO:0048168 1 0.038
cellular amino acid metabolic process GO:0006520 7 0.037
posterior lateral line nerve glial cell development GO:0048941 5 0.037
protein localization to membrane GO:0072657 9 0.037
regulation of biosynthetic process GO:0009889 250 0.036
cytoskeleton organization GO:0007010 96 0.036
monovalent inorganic cation homeostasis GO:0055067 9 0.036
axonogenesis GO:0007409 152 0.036
ion homeostasis GO:0050801 41 0.036
Rat
guanosine containing compound metabolic process GO:1901068 4 0.036
cellular component morphogenesis GO:0032989 336 0.035
neuroblast differentiation GO:0014016 1 0.035
cellular amino acid biosynthetic process GO:0008652 2 0.035
cell migration involved in gastrulation GO:0042074 79 0.035
g protein coupled receptor signaling pathway GO:0007186 74 0.035
fertilization GO:0009566 3 0.034
heterocycle biosynthetic process GO:0018130 215 0.034
organic cyclic compound catabolic process GO:1901361 15 0.034
gtp metabolic process GO:0046039 4 0.034
nucleoside phosphate metabolic process GO:0006753 28 0.034
regulation of reproductive process GO:2000241 4 0.033
response to drug GO:0042493 3 0.033
regulation of phosphorus metabolic process GO:0051174 43 0.033
positive regulation of transport GO:0051050 2 0.033
actomyosin structure organization GO:0031032 53 0.033
regulation of phosphate metabolic process GO:0019220 43 0.032
neuron projection morphogenesis GO:0048812 161 0.032
skeletal system morphogenesis GO:0048705 102 0.032
digestive system development GO:0055123 289 0.032
ventral spinal cord interneuron fate commitment GO:0060579 3 0.032
rhodopsin mediated signaling pathway GO:0016056 1 0.031
catabolic process GO:0009056 32 0.031
phosphorus metabolic process GO:0006793 109 0.031
posterior lateral line development GO:0048916 38 0.031
positive regulation of camp biosynthetic process GO:0030819 2 0.031
regulation of programmed cell death GO:0043067 101 0.031
gastrulation GO:0007369 208 0.031
regulation of membrane potential GO:0042391 23 0.030
biosynthetic process GO:0009058 294 0.030
endocardium formation GO:0060214 1 0.030
phosphate containing compound metabolic process GO:0006796 108 0.030
purine containing compound metabolic process GO:0072521 29 0.030
forebrain development GO:0030900 96 0.030
regulation of cytoplasmic transport GO:1903649 4 0.030
cortical actin cytoskeleton organization GO:0030866 1 0.030
tube morphogenesis GO:0035239 349 0.029
purine nucleoside monophosphate catabolic process GO:0009128 4 0.029
microtubule cytoskeleton organization GO:0000226 33 0.029
divalent inorganic cation homeostasis GO:0072507 22 0.029
Rat
atp catabolic process GO:0006200 4 0.028
response to stress GO:0006950 263 0.028
regulation of metabolic process GO:0019222 359 0.027
nucleocytoplasmic transport GO:0006913 4 0.027
potassium ion transport GO:0006813 10 0.027
guanosine containing compound catabolic process GO:1901069 2 0.026
single organism localization GO:1902578 225 0.026
purine ribonucleotide metabolic process GO:0009150 27 0.026
cell division GO:0051301 20 0.025
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.025
cortical cytoskeleton organization GO:0030865 1 0.025
glucose homeostasis GO:0042593 1 0.025
ear development GO:0043583 127 0.025
regulation of biological quality GO:0065008 263 0.025
Rat
regulation of multicellular organismal process GO:0051239 277 0.024
nucleobase containing small molecule metabolic process GO:0055086 32 0.024
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.024
reproduction GO:0000003 40 0.024
cellular catabolic process GO:0044248 27 0.024
neuroblast fate commitment GO:0014017 1 0.024
ribose phosphate metabolic process GO:0019693 27 0.024
negative regulation of heart contraction GO:0045822 2 0.023
sensory perception of chemical stimulus GO:0007606 3 0.023
chemical homeostasis GO:0048878 49 0.023
Rat
peripheral nervous system neuron differentiation GO:0048934 28 0.023
otolith development GO:0048840 32 0.023
cellular nitrogen compound catabolic process GO:0044270 15 0.023
membrane repolarization GO:0086009 2 0.023
regulation of cell development GO:0060284 100 0.022
regulation of transport GO:0051049 45 0.022
death GO:0016265 121 0.022
hindbrain development GO:0030902 91 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.022
cellular protein localization GO:0034613 20 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.022
cell death GO:0008219 121 0.022
aging GO:0007568 2 0.021
positive regulation of biological process GO:0048518 253 0.021
regulation of molecular function GO:0065009 70 0.021
transmembrane transport GO:0055085 120 0.021
exocytosis GO:0006887 1 0.021
neuron projection development GO:0031175 180 0.021
neural tube development GO:0021915 62 0.021
muscle structure development GO:0061061 196 0.021
positive regulation of metabolic process GO:0009893 108 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
carboxylic acid catabolic process GO:0046395 3 0.020
regulation of cellular metabolic process GO:0031323 320 0.020
cellular component assembly GO:0022607 170 0.020
protein localization GO:0008104 40 0.020
nerve development GO:0021675 45 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.019
establishment of mitotic spindle orientation GO:0000132 10 0.019
rna biosynthetic process GO:0032774 181 0.019
ribonucleoside monophosphate catabolic process GO:0009158 4 0.019
axon regeneration GO:0031103 14 0.019
regulation of sodium ion transport GO:0002028 2 0.019
cell growth GO:0016049 57 0.018
heart development GO:0007507 313 0.018
response to wounding GO:0009611 116 0.018
neurotransmitter biosynthetic process GO:0042136 2 0.018
inorganic ion transmembrane transport GO:0098660 57 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.018
negative regulation of developmental process GO:0051093 65 0.018
cellular biosynthetic process GO:0044249 286 0.017
response to nutrient GO:0007584 3 0.017
regulation of neuron differentiation GO:0045664 56 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
cell surface receptor signaling pathway GO:0007166 325 0.017
detection of stimulus GO:0051606 29 0.017
cellular component biogenesis GO:0044085 178 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
aromatic compound catabolic process GO:0019439 15 0.017
regulation of localization GO:0032879 104 0.016
lateral line system development GO:0048925 76 0.016
nuclear transport GO:0051169 4 0.016
positive regulation of signaling GO:0023056 56 0.016
asymmetric protein localization GO:0008105 6 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
positive regulation of neuron death GO:1901216 1 0.016
axon extension GO:0048675 45 0.016
cell proliferation GO:0008283 80 0.016
septum transversum development GO:0003343 4 0.015
reproductive process GO:0022414 40 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
anterior commissure morphogenesis GO:0021960 3 0.015
organelle organization GO:0006996 227 0.015
organic substance transport GO:0071702 58 0.015
alpha amino acid metabolic process GO:1901605 3 0.015
transport GO:0006810 220 0.015
neuromuscular synaptic transmission GO:0007274 2 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.015
multicellular organism reproduction GO:0032504 35 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
angiogenesis GO:0001525 158 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
morphogenesis of an epithelial sheet GO:0002011 49 0.015
single organism membrane organization GO:0044802 20 0.015
heart contraction GO:0060047 71 0.014
transcription dna templated GO:0006351 181 0.014
single organism intracellular transport GO:1902582 25 0.014
single organism biosynthetic process GO:0044711 71 0.014
positive regulation of macromolecule metabolic process GO:0010604 93 0.014
regulation of gtpase activity GO:0043087 2 0.014
intracellular signal transduction GO:0035556 85 0.014
negative regulation of sequestering of calcium ion GO:0051283 4 0.014
calcium ion homeostasis GO:0055074 19 0.014
Rat
midbrain development GO:0030901 28 0.014
cell projection morphogenesis GO:0048858 244 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.013
regulation of muscle contraction GO:0006937 3 0.013
dopaminergic neuron differentiation GO:0071542 14 0.013
neuroblast fate determination GO:0007400 1 0.013
single fertilization GO:0007338 3 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
pons development GO:0021548 11 0.013
muscle contraction GO:0006936 18 0.013
neuron neuron synaptic transmission GO:0007270 1 0.013
positive regulation of catabolic process GO:0009896 4 0.013
multi organism reproductive process GO:0044703 36 0.013
semicircular canal morphogenesis GO:0048752 18 0.013
actin filament organization GO:0007015 15 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
macromolecule biosynthetic process GO:0009059 227 0.012
positive regulation of transcription dna templated GO:0045893 57 0.012
immune system development GO:0002520 191 0.012
establishment of cell polarity GO:0030010 18 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
single organism membrane fusion GO:0044801 2 0.012
anterior posterior pattern specification GO:0009952 152 0.012
oxoacid metabolic process GO:0043436 31 0.012
cell cell junction organization GO:0045216 10 0.012
proepicardium development GO:0003342 4 0.012
startle response GO:0001964 4 0.012
skin development GO:0043588 54 0.012
neurological system process GO:0050877 62 0.012
regulation of cell cell adhesion GO:0022407 13 0.012
regulation of postsynaptic membrane potential GO:0060078 1 0.011
phosphorylation GO:0016310 69 0.011
organic acid metabolic process GO:0006082 31 0.011
rna metabolic process GO:0016070 219 0.011
cell cell signaling GO:0007267 52 0.011
negative regulation of gliogenesis GO:0014014 1 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
skeletal muscle tissue development GO:0007519 67 0.011
mechanosensory lateral line system development GO:0048881 49 0.011
positive regulation of neuron apoptotic process GO:0043525 1 0.011
posterior lateral line neuromast primordium migration GO:0048920 12 0.011
embryonic viscerocranium morphogenesis GO:0048703 52 0.011
neuromast primordium migration GO:0048883 12 0.011
response to abiotic stimulus GO:0009628 122 0.011
cell substrate adhesion GO:0031589 4 0.011
response to axon injury GO:0048678 14 0.011
embryonic organ development GO:0048568 381 0.011
membrane organization GO:0061024 21 0.010
cellular macromolecule biosynthetic process GO:0034645 224 0.010
locus ceruleus development GO:0021703 3 0.010
cell part morphogenesis GO:0032990 246 0.010
response to immobilization stress GO:0035902 1 0.010
regulation of anatomical structure size GO:0090066 33 0.010
neuron differentiation GO:0030182 353 0.010
regulation of nucleic acid templated transcription GO:1903506 213 0.010
respiratory system development GO:0060541 5 0.010
establishment of mitotic spindle localization GO:0040001 12 0.010
establishment of spindle orientation GO:0051294 10 0.010
posttranscriptional regulation of gene expression GO:0010608 14 0.010
response to radiation GO:0009314 51 0.010

calb2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.037
disease of anatomical entity DOID:7 0 0.037
thyroid cancer DOID:1781 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
cancer DOID:162 0 0.024
organ system cancer DOID:0050686 0 0.024
thyroid carcinoma DOID:3963 0 0.024
endocrine gland cancer DOID:170 0 0.024