Danio rerio

0 known processes

calr

calreticulin and calreticulin

(Aliases: zgc:85636)

calr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to topologically incorrect protein GO:0035967 2 0.973
Worm
endoplasmic reticulum unfolded protein response GO:0030968 2 0.607
Worm
response to endoplasmic reticulum stress GO:0034976 6 0.589
Worm
er nucleus signaling pathway GO:0006984 2 0.588
Worm
cellular response to unfolded protein GO:0034620 2 0.405
Worm
larval development GO:0002164 2 0.390
Worm
response to stress GO:0006950 263 0.305
Worm
response to topologically incorrect protein GO:0035966 2 0.303
Worm
response to unfolded protein GO:0006986 2 0.250
Worm
signal transduction GO:0007165 455 0.237
Worm
cellular protein metabolic process GO:0044267 129 0.236
Mouse
protein n linked glycosylation GO:0006487 1 0.210
protein metabolic process GO:0019538 183 0.188
Mouse
multicellular organism growth GO:0035264 4 0.172
cell death GO:0008219 121 0.161
Worm
cellular macromolecule metabolic process GO:0044260 391 0.133
Mouse
aging GO:0007568 2 0.130
regulation of multicellular organism growth GO:0040014 4 0.111
hormone transport GO:0009914 2 0.105
growth GO:0040007 174 0.097
maintenance of location GO:0051235 4 0.096
programmed cell death GO:0012501 119 0.095
Worm
cellular protein catabolic process GO:0044257 4 0.091
positive regulation of developmental process GO:0051094 50 0.087
regulation of signaling GO:0023051 235 0.087
positive regulation of secretion by cell GO:1903532 1 0.084
proteasomal protein catabolic process GO:0010498 2 0.084
embryo development ending in birth or egg hatching GO:0009792 271 0.077
cell substrate junction assembly GO:0007044 2 0.065
Worm
modification dependent macromolecule catabolic process GO:0043632 3 0.065
developmental growth GO:0048589 166 0.064
single organism localization GO:1902578 225 0.057
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.056
lipid storage GO:0019915 1 0.055
death GO:0016265 121 0.055
Worm
cell surface receptor signaling pathway GO:0007166 325 0.052
cellular response to organic substance GO:0071310 105 0.051
Worm
response to organic substance GO:0010033 153 0.049
Worm
modification dependent protein catabolic process GO:0019941 3 0.048
regulation of cell communication GO:0010646 232 0.047
regulation of growth GO:0040008 42 0.046
regulation of response to stimulus GO:0048583 269 0.046
regulation of cell death GO:0010941 103 0.045
regulation of blood pressure GO:0008217 1 0.045
positive regulation of biological process GO:0048518 253 0.044
response to heat GO:0009408 6 0.043
Worm
extrinsic apoptotic signaling pathway GO:0097191 3 0.042
regulation of hormone secretion GO:0046883 2 0.039
positive regulation of translation GO:0045727 1 0.039
positive regulation of transport GO:0051050 2 0.039
cellular protein modification process GO:0006464 100 0.039
response to abiotic stimulus GO:0009628 122 0.039
Worm
peptide transport GO:0015833 1 0.038
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.037
regulation of blood vessel size GO:0050880 2 0.036
golgi vesicle transport GO:0048193 3 0.036
amine metabolic process GO:0009308 2 0.035
regulation of multicellular organismal process GO:0051239 277 0.035
cellular response to chemical stimulus GO:0070887 157 0.035
Worm
response to temperature stimulus GO:0009266 15 0.035
Worm
transport GO:0006810 220 0.035
regulation of organ growth GO:0046620 3 0.034
ubiquitin dependent protein catabolic process GO:0006511 3 0.033
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.033
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.033
response to chemical GO:0042221 320 0.033
Worm
positive regulation of embryonic development GO:0040019 3 0.031
endodermal digestive tract morphogenesis GO:0061031 2 0.030
positive regulation of muscle cell differentiation GO:0051149 1 0.030
positive regulation of apoptotic signaling pathway GO:2001235 1 0.029
regulation of signal transduction GO:0009966 225 0.029
regulation of developmental process GO:0050793 247 0.028
response to alcohol GO:0097305 14 0.028
Worm
hormone secretion GO:0046879 2 0.028
positive regulation of cell activation GO:0050867 1 0.027
apoptotic process GO:0006915 116 0.027
regulation of cell activation GO:0050865 1 0.026
protein modification process GO:0036211 100 0.026
adult behavior GO:0030534 2 0.026
regulation of cell shape GO:0008360 1 0.026
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.026
regulation of biological quality GO:0065008 263 0.025
multicellular organismal reproductive process GO:0048609 35 0.025
Worm
autophagy GO:0006914 4 0.025
protein targeting to nucleus GO:0044744 3 0.024
regulation of transmembrane transporter activity GO:0022898 2 0.024
positive regulation of cytokine production GO:0001819 2 0.024
positive regulation of cellular process GO:0048522 201 0.024
meiotic nuclear division GO:0007126 4 0.023
positive regulation of multicellular organismal process GO:0051240 52 0.023
regulation of systemic arterial blood pressure GO:0003073 1 0.022
macromolecule modification GO:0043412 111 0.022
multi organism process GO:0051704 134 0.022
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.022
negative regulation of cellular process GO:0048523 283 0.021
regulation of protein transport GO:0051223 3 0.021
cellular response to endogenous stimulus GO:0071495 68 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
regulation of protein ubiquitination GO:0031396 3 0.021
cellular response to organic cyclic compound GO:0071407 38 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
multicellular organismal metabolic process GO:0044236 2 0.020
response to ketone GO:1901654 1 0.020
single organism metabolic process GO:0044710 217 0.020
response to decreased oxygen levels GO:0036293 25 0.020
mitotic cell cycle GO:0000278 64 0.020
cellular response to stress GO:0033554 62 0.019
Worm
exocytosis GO:0006887 1 0.019
regulation of apoptotic process GO:0042981 98 0.019
cellular response to nutrient levels GO:0031669 2 0.019
response to hypoxia GO:0001666 25 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
rna localization GO:0006403 4 0.018
protein import GO:0017038 3 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
regulation of cellular response to growth factor stimulus GO:0090287 35 0.018
regulation of ion transmembrane transporter activity GO:0032412 2 0.018
double strand break repair GO:0006302 3 0.018
regulation of metal ion transport GO:0010959 4 0.017
cellular response to antibiotic GO:0071236 1 0.017
regulation of cytokine production GO:0001817 3 0.017
head development GO:0060322 303 0.017
biosynthetic process GO:0009058 294 0.017
cellular localization GO:0051641 97 0.017
negative regulation of cell communication GO:0010648 96 0.017
cell motility GO:0048870 244 0.017
collagen metabolic process GO:0032963 2 0.017
regulation of tube size GO:0035150 2 0.017
digestive system development GO:0055123 289 0.016
response to wounding GO:0009611 116 0.016
regulation of binding GO:0051098 3 0.016
multicellular organismal macromolecule metabolic process GO:0044259 2 0.016
sexual reproduction GO:0019953 36 0.016
negative regulation of signaling GO:0023057 96 0.016
response to biotic stimulus GO:0009607 97 0.015
gtp metabolic process GO:0046039 4 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
cell junction organization GO:0034330 11 0.015
Worm
response to ethanol GO:0045471 6 0.015
Worm
negative regulation of cellular catabolic process GO:0031330 3 0.015
cellular response to starvation GO:0009267 1 0.014
angiogenesis GO:0001525 158 0.014
embryonic organ development GO:0048568 381 0.014
regulation of transporter activity GO:0032409 2 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
cell morphogenesis GO:0000902 289 0.014
single organism transport GO:0044765 206 0.014
nuclear import GO:0051170 3 0.014
negative regulation of chromosome organization GO:2001251 1 0.014
cellular catabolic process GO:0044248 27 0.014
proteolysis GO:0006508 38 0.013
multicellular organism reproduction GO:0032504 35 0.013
Worm
regulation of protein catabolic process GO:0042176 1 0.013
positive regulation of cell cycle GO:0045787 3 0.013
cell aging GO:0007569 2 0.013
central nervous system development GO:0007417 387 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
protein import into nucleus GO:0006606 3 0.013
single organism nuclear import GO:1902593 3 0.013
organic substance biosynthetic process GO:1901576 289 0.013
organelle organization GO:0006996 227 0.013
mononuclear cell proliferation GO:0032943 1 0.013
production of molecular mediator of immune response GO:0002440 2 0.012
meiotic cell cycle process GO:1903046 3 0.012
cellular amide metabolic process GO:0043603 4 0.012
cellular response to toxic substance GO:0097237 1 0.012
midbrain development GO:0030901 28 0.012
locomotion GO:0040011 313 0.012
Worm
regulation of programmed cell death GO:0043067 101 0.012
establishment of localization GO:0051234 244 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
transmembrane transport GO:0055085 120 0.012
phosphorus metabolic process GO:0006793 109 0.012
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.012
digestive tract development GO:0048565 265 0.012
response to nitrogen compound GO:1901698 19 0.011
negative regulation of biological process GO:0048519 304 0.011
response to antibiotic GO:0046677 1 0.011
organic substance catabolic process GO:1901575 28 0.011
cellular component morphogenesis GO:0032989 336 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
viral process GO:0016032 1 0.011
reproduction GO:0000003 40 0.011
Worm
sensory organ development GO:0007423 393 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
positive regulation of signaling GO:0023056 56 0.011
regulation of localization GO:0032879 104 0.011
inorganic ion transmembrane transport GO:0098660 57 0.011
regulation of metabolic process GO:0019222 359 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.010
regulation of nucleocytoplasmic transport GO:0046822 2 0.010
macromolecule biosynthetic process GO:0009059 227 0.010
cell migration GO:0016477 237 0.010
internal protein amino acid acetylation GO:0006475 2 0.010
regulation of cellular ketone metabolic process GO:0010565 7 0.010
carbohydrate homeostasis GO:0033500 1 0.010
interspecies interaction between organisms GO:0044419 4 0.010
regulation of inflammatory response GO:0050727 2 0.010
meiotic chromosome segregation GO:0045132 3 0.010

calr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.050
nervous system disease DOID:863 0 0.021
sensory system disease DOID:0050155 0 0.014
nonsyndromic deafness DOID:0050563 0 0.014
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.014
auditory system disease DOID:2742 0 0.014
musculoskeletal system disease DOID:17 0 0.014
muscular disease DOID:0080000 0 0.013
myopathy DOID:423 0 0.013
muscle tissue disease DOID:66 0 0.013