Danio rerio

0 known processes

capza1b

capping protein (actin filament) muscle Z-line, alpha 1b

(Aliases: sb:cb852,zK16K6.1,si:dkey-16k6.1,wu:fj45f05,zgc:101755,wu:fb36c09,wu:fc85a01)

capza1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin polymerization or depolymerization GO:0008154 2 0.478
Fly
larval development GO:0002164 2 0.341
Worm
single organism organelle organization GO:1902589 199 0.247
Fly
cellular component morphogenesis GO:0032989 336 0.200
Fly
cellular component assembly GO:0022607 170 0.197
Fly
cellular component biogenesis GO:0044085 178 0.185
Fly
organelle organization GO:0006996 227 0.181
Fly
cytoskeleton organization GO:0007010 96 0.171
Fly
regulation of metabolic process GO:0019222 359 0.166
Fly
meiotic nuclear division GO:0007126 4 0.158
nuclear migration GO:0007097 3 0.157
regulation of cell projection assembly GO:0060491 4 0.149
Fly
negative regulation of cellular process GO:0048523 283 0.126
Fly
negative regulation of biological process GO:0048519 304 0.125
Fly
phagocytosis GO:0006909 3 0.118
Fly
cellular response to extracellular stimulus GO:0031668 2 0.113
organelle assembly GO:0070925 110 0.107
regulation of protein polymerization GO:0032271 2 0.103
Fly
macromolecular complex assembly GO:0065003 35 0.100
Fly
mitochondrion organization GO:0007005 4 0.100
locomotion GO:0040011 313 0.099
response to amino acid GO:0043200 2 0.097
regulation of macromolecule metabolic process GO:0060255 317 0.091
positive regulation of cellular component biogenesis GO:0044089 3 0.087
release of sequestered calcium ion into cytosol GO:0051209 3 0.084
cell morphogenesis GO:0000902 289 0.082
Fly
digestive tract development GO:0048565 265 0.079
positive regulation of transport GO:0051050 2 0.078
sleep GO:0030431 1 0.077
cell surface receptor signaling pathway GO:0007166 325 0.075
stem cell proliferation GO:0072089 4 0.075
cell projection assembly GO:0030031 64 0.074
Fly
protein polymerization GO:0051258 4 0.072
Fly
regulation of signal transduction GO:0009966 225 0.071
Fly
digestive tract morphogenesis GO:0048546 231 0.071
maintenance of location GO:0051235 4 0.069
blood vessel development GO:0001568 246 0.068
regulation of response to stimulus GO:0048583 269 0.067
Fly
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.065
negative regulation of sequestering of calcium ion GO:0051283 4 0.064
cellular nitrogen compound metabolic process GO:0034641 290 0.064
single organism reproductive process GO:0044702 40 0.062
Mouse Fly
cell cycle GO:0007049 93 0.061
cellular response to nutrient levels GO:0031669 2 0.061
signal transduction GO:0007165 455 0.061
Fly
regulation of cell communication GO:0010646 232 0.058
Fly
angiogenesis GO:0001525 158 0.058
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.058
nuclear transport GO:0051169 4 0.057
apoptotic process GO:0006915 116 0.056
Worm
cellular localization GO:0051641 97 0.055
maternal determination of anterior posterior axis embryo GO:0008358 4 0.055
pole plasm assembly GO:0007315 4 0.054
cell projection organization GO:0030030 284 0.054
Fly
endosomal transport GO:0016197 2 0.053
cytosolic calcium ion transport GO:0060401 3 0.053
embryo development ending in birth or egg hatching GO:0009792 271 0.052
Worm
heterocycle metabolic process GO:0046483 290 0.051
gastrulation GO:0007369 208 0.051
organelle localization GO:0051640 49 0.050
autophagy GO:0006914 4 0.049
aging GO:0007568 2 0.049
cytokinesis GO:0000910 3 0.048
protein complex biogenesis GO:0070271 30 0.048
Fly
regulation of protein depolymerization GO:1901879 1 0.047
Fly
tube morphogenesis GO:0035239 349 0.047
cellular response to external stimulus GO:0071496 2 0.047
cellular amine metabolic process GO:0044106 2 0.047
guanosine containing compound catabolic process GO:1901069 2 0.046
establishment of localization GO:0051234 244 0.046
Fly
actin cytoskeleton organization GO:0030036 63 0.046
Fly
transport GO:0006810 220 0.045
Fly
cellular response to starvation GO:0009267 1 0.045
developmental maturation GO:0021700 34 0.044
cell morphogenesis involved in differentiation GO:0000904 195 0.044
spermatid differentiation GO:0048515 2 0.044
Mouse
protein complex subunit organization GO:0071822 46 0.043
Fly
female meiotic division GO:0007143 2 0.043
positive regulation of secretion by cell GO:1903532 1 0.043
cytoplasm organization GO:0007028 4 0.042
regulation of signaling GO:0023051 235 0.042
Fly
phagocytosis engulfment GO:0006911 1 0.042
regulation of cytoskeleton organization GO:0051493 11 0.041
Fly
macromolecular complex disassembly GO:0032984 1 0.041
Fly
hatching GO:0035188 4 0.040
spermatid development GO:0007286 2 0.039
Mouse
death GO:0016265 121 0.039
Worm
neuroblast proliferation GO:0007405 2 0.039
regulation of establishment of protein localization GO:0070201 4 0.038
cellular macromolecule metabolic process GO:0044260 391 0.038
mitotic cell cycle GO:0000278 64 0.037
cell part morphogenesis GO:0032990 246 0.037
cellular protein metabolic process GO:0044267 129 0.037
regulation of gene expression GO:0010468 265 0.036
cortical cytoskeleton organization GO:0030865 1 0.036
digestive system development GO:0055123 289 0.036
cellular biosynthetic process GO:0044249 286 0.036
amine metabolic process GO:0009308 2 0.035
nucleic acid transport GO:0050657 2 0.035
negative regulation of protein complex assembly GO:0031333 1 0.035
Fly
cellular amino acid metabolic process GO:0006520 7 0.034
regulation of biological quality GO:0065008 263 0.034
Fly
single organism localization GO:1902578 225 0.034
Fly
gtp catabolic process GO:0006184 2 0.034
regulation of cellular component organization GO:0051128 86 0.034
Fly
cell migration GO:0016477 237 0.033
protein import GO:0017038 3 0.033
gtp metabolic process GO:0046039 4 0.033
regulation of metal ion transport GO:0010959 4 0.033
oocyte anterior posterior axis specification GO:0007314 4 0.033
positive regulation of biological process GO:0048518 253 0.032
single fertilization GO:0007338 3 0.031
single organism transport GO:0044765 206 0.031
Fly
cognition GO:0050890 1 0.031
response to carbohydrate GO:0009743 3 0.031
regulation of anatomical structure morphogenesis GO:0022603 130 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.030
regulation of protein complex disassembly GO:0043244 1 0.030
Fly
system process GO:0003008 185 0.030
cellular aromatic compound metabolic process GO:0006725 295 0.030
regulation of protein transport GO:0051223 3 0.029
stem cell differentiation GO:0048863 117 0.029
organic substance biosynthetic process GO:1901576 289 0.029
calcium ion transport into cytosol GO:0060402 3 0.029
regulation of cytoplasmic transport GO:1903649 4 0.029
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.029
reproductive process GO:0022414 40 0.029
Mouse Fly
sequestering of calcium ion GO:0051208 3 0.029
cell death GO:0008219 121 0.028
Worm
carboxylic acid metabolic process GO:0019752 22 0.028
organic acid metabolic process GO:0006082 31 0.028
protein complex disassembly GO:0043241 1 0.028
Fly
protein depolymerization GO:0051261 1 0.028
Fly
leukocyte proliferation GO:0070661 1 0.028
gene expression GO:0010467 252 0.028
somatic muscle development GO:0007525 4 0.028
multicellular organism growth GO:0035264 4 0.028
regulation of binding GO:0051098 3 0.027
chordate embryonic development GO:0043009 271 0.027
lipid storage GO:0019915 1 0.027
heart process GO:0003015 71 0.027
establishment of localization in cell GO:0051649 77 0.027
cellular component disassembly GO:0022411 1 0.027
Fly
regulation of protein complex assembly GO:0043254 3 0.027
Fly
intracellular signal transduction GO:0035556 85 0.027
Fly
response to glucose GO:0009749 3 0.027
regulation of multicellular organism growth GO:0040014 4 0.026
nitrogen compound metabolic process GO:0006807 319 0.026
oocyte development GO:0048599 14 0.026
meiotic cell cycle process GO:1903046 3 0.026
regulation of cell shape GO:0008360 1 0.026
peptide transport GO:0015833 1 0.026
small molecule metabolic process GO:0044281 77 0.026
compound eye development GO:0048749 2 0.026
generation of neurons GO:0048699 385 0.025
muscle cell differentiation GO:0042692 139 0.025
regulation of dendrite morphogenesis GO:0048814 3 0.025
membrane invagination GO:0010324 1 0.025
hormone transport GO:0009914 2 0.025
microtubule based process GO:0007017 60 0.025
programmed cell death GO:0012501 119 0.025
Worm
multi organism process GO:0051704 134 0.025
Mouse Fly
nucleobase containing compound metabolic process GO:0006139 274 0.024
nucleocytoplasmic transport GO:0006913 4 0.024
reproduction GO:0000003 40 0.024
Mouse Worm Fly
adherens junction organization GO:0034332 4 0.024
neuron development GO:0048666 262 0.024
cellular protein complex assembly GO:0043623 19 0.024
Fly
organelle fusion GO:0048284 3 0.024
response to chemical GO:0042221 320 0.024
carbohydrate homeostasis GO:0033500 1 0.023
somite development GO:0061053 96 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.023
multicellular organismal macromolecule metabolic process GO:0044259 2 0.023
protein secretion GO:0009306 1 0.023
organic cyclic compound metabolic process GO:1901360 301 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
regulation of organelle organization GO:0033043 29 0.023
Fly
nuclear division GO:0000280 23 0.023
regulation of developmental process GO:0050793 247 0.023
regulation of transporter activity GO:0032409 2 0.023
oxoacid metabolic process GO:0043436 31 0.023
cell cycle process GO:0022402 53 0.023
multicellular organismal metabolic process GO:0044236 2 0.023
cellular component movement GO:0006928 335 0.023
localization of cell GO:0051674 244 0.023
single organism metabolic process GO:0044710 217 0.023
Fly
nuclear import GO:0051170 3 0.022
rna localization GO:0006403 4 0.022
chemical homeostasis GO:0048878 49 0.022
regulation of hormone secretion GO:0046883 2 0.022
meiotic chromosome segregation GO:0045132 3 0.022
negative regulation of response to stimulus GO:0048585 104 0.022
Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.022
peptidyl threonine phosphorylation GO:0018107 1 0.022
neurotransmitter secretion GO:0007269 2 0.022
regulation of dendrite development GO:0050773 3 0.021
response to hexose GO:0009746 3 0.021
cellular component assembly involved in morphogenesis GO:0010927 107 0.021
morphogenesis of an epithelium GO:0002009 333 0.021
neuron neuron synaptic transmission GO:0007270 1 0.021
nucleic acid metabolic process GO:0090304 244 0.021
response to external stimulus GO:0009605 264 0.021
regulation of neural precursor cell proliferation GO:2000177 3 0.021
pyruvate metabolic process GO:0006090 1 0.020
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.020
cell projection morphogenesis GO:0048858 244 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
rna biosynthetic process GO:0032774 181 0.020
actin filament polymerization GO:0030041 2 0.020
Fly
regulation of filopodium assembly GO:0051489 2 0.020
Fly
regulation of protein localization to nucleus GO:1900180 2 0.020
regulation of sequestering of calcium ion GO:0051282 4 0.020
protein localization to plasma membrane GO:0072659 1 0.020
cellular macromolecular complex assembly GO:0034622 24 0.020
Fly
neuron projection morphogenesis GO:0048812 161 0.020
cellular protein catabolic process GO:0044257 4 0.020
guanosine containing compound metabolic process GO:1901068 4 0.020
transmission of nerve impulse GO:0019226 19 0.020
hormone secretion GO:0046879 2 0.020
cellular ketone metabolic process GO:0042180 11 0.019
striated muscle cell development GO:0055002 108 0.019
regionalization GO:0003002 274 0.019
regulation of gtp catabolic process GO:0033124 2 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
ras protein signal transduction GO:0007265 7 0.019
small gtpase mediated signal transduction GO:0007264 8 0.019
regulation of programmed cell death GO:0043067 101 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
macroautophagy GO:0016236 1 0.019
macromolecular complex subunit organization GO:0043933 74 0.019
Fly
positive regulation of muscle cell differentiation GO:0051149 1 0.019
regulation of ion transmembrane transporter activity GO:0032412 2 0.018
response to abiotic stimulus GO:0009628 122 0.018
protein import into nucleus GO:0006606 3 0.018
protein acetylation GO:0006473 2 0.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.018
carbohydrate derivative metabolic process GO:1901135 61 0.018
positive regulation of gtp catabolic process GO:0033126 1 0.018
nitrogen compound transport GO:0071705 23 0.018
regulation of multicellular organismal development GO:2000026 223 0.018
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.018
Mouse Fly
synaptic vesicle transport GO:0048489 1 0.018
establishment of rna localization GO:0051236 3 0.018
reactive oxygen species metabolic process GO:0072593 6 0.018
sequestering of metal ion GO:0051238 3 0.017
membrane fusion GO:0061025 2 0.017
mitotic cell cycle process GO:1903047 48 0.017
regulation of apoptotic process GO:0042981 98 0.017
nucleobase containing compound transport GO:0015931 2 0.017
single organism nuclear import GO:1902593 3 0.017
biosynthetic process GO:0009058 294 0.017
organic substance transport GO:0071702 58 0.017
positive regulation of ras protein signal transduction GO:0046579 1 0.017
neuron projection development GO:0031175 180 0.017
organelle fission GO:0048285 23 0.017
positive regulation of cytoskeleton organization GO:0051495 3 0.017
regulation of neurogenesis GO:0050767 87 0.017
microtubule organizing center organization GO:0031023 1 0.017
regulation of cell death GO:0010941 103 0.017
rna transport GO:0050658 2 0.017
regulation of rna metabolic process GO:0051252 224 0.017
regulation of reproductive process GO:2000241 4 0.016
protein metabolic process GO:0019538 183 0.016
vasculature development GO:0001944 278 0.016
homeostatic process GO:0042592 142 0.016
regulation of myotube differentiation GO:0010830 2 0.016
establishment of synaptic vesicle localization GO:0097480 1 0.016
cell division GO:0051301 20 0.016
inorganic cation transmembrane transport GO:0098662 50 0.016
protein acylation GO:0043543 3 0.016
regulation of localization GO:0032879 104 0.016
response to monosaccharide GO:0034284 3 0.016
multicellular organismal signaling GO:0035637 22 0.016
negative regulation of cell communication GO:0010648 96 0.016
Fly
regulation of ph GO:0006885 3 0.016
macromolecule localization GO:0033036 54 0.016
response to nutrient GO:0007584 3 0.016
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.016
cation transmembrane transport GO:0098655 65 0.016
amino acid transport GO:0006865 2 0.015
protein localization to nucleus GO:0034504 3 0.015
positive regulation of cell communication GO:0010647 56 0.015
glucose homeostasis GO:0042593 1 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
cell substrate adhesion GO:0031589 4 0.015
regulation of natural killer cell mediated immunity GO:0002715 1 0.015
positive regulation of signaling GO:0023056 56 0.015
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
positive regulation of secretion GO:0051047 1 0.015
mitotic nuclear division GO:0007067 18 0.015
single organism cellular localization GO:1902580 46 0.015
stem cell maintenance GO:0019827 4 0.015
segmentation GO:0035282 97 0.015
calcium mediated signaling GO:0019722 2 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
axonogenesis GO:0007409 152 0.015
positive regulation of catabolic process GO:0009896 4 0.015
neuron differentiation GO:0030182 353 0.015
transcription dna templated GO:0006351 181 0.014
neurotransmitter transport GO:0006836 2 0.014
vacuolar transport GO:0007034 2 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
regulation of muscle contraction GO:0006937 3 0.014
ion transmembrane transport GO:0034220 91 0.014
positive regulation of multicellular organismal process GO:0051240 52 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
anterior posterior pattern specification GO:0009952 152 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
developmental process involved in reproduction GO:0003006 27 0.014
Mouse Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.014
wnt signaling pathway GO:0016055 80 0.014
regulation of cell activation GO:0050865 1 0.014
regulation of mrna processing GO:0050684 3 0.014
protein localization GO:0008104 40 0.013
chemosensory behavior GO:0007635 1 0.013
establishment of protein localization to plasma membrane GO:0090002 1 0.013
protein targeting to nucleus GO:0044744 3 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.013
negative regulation of kinase activity GO:0033673 4 0.013
cell aging GO:0007569 2 0.013
positive regulation of glucose transport GO:0010828 1 0.013
actin filament based process GO:0030029 64 0.013
Fly
transmembrane transport GO:0055085 120 0.013
neurological system process GO:0050877 62 0.013
lamellipodium assembly GO:0030032 1 0.013
Fly
intracellular transport GO:0046907 32 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
regulation of canonical wnt signaling pathway GO:0060828 34 0.013
pronuclear migration GO:0035046 1 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
fertilization GO:0009566 3 0.013
cell maturation GO:0048469 23 0.013
blood vessel morphogenesis GO:0048514 216 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
muscle cell development GO:0055001 115 0.013
intracellular mrna localization GO:0008298 1 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
regulation of wnt signaling pathway GO:0030111 53 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
establishment of organelle localization GO:0051656 45 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
negative regulation of cell differentiation GO:0045596 46 0.012
negative regulation of protein import into nucleus GO:0042308 2 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
positive regulation of striated muscle cell differentiation GO:0051155 1 0.012
trabecula morphogenesis GO:0061383 2 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
inorganic ion transmembrane transport GO:0098660 57 0.012
centrosome organization GO:0051297 1 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
Fly
phototransduction GO:0007602 2 0.012
somitogenesis GO:0001756 87 0.012
negative regulation of signal transduction GO:0009968 94 0.012
Fly
regulation of protein ubiquitination GO:0031396 3 0.012
muscle fiber development GO:0048747 52 0.012
rho protein signal transduction GO:0007266 5 0.011
collagen metabolic process GO:0032963 2 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
cellular modified amino acid metabolic process GO:0006575 3 0.011
receptor internalization GO:0031623 2 0.011
developmental growth GO:0048589 166 0.011
cilium morphogenesis GO:0060271 85 0.011
cellular amide metabolic process GO:0043603 4 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
protein localization to vacuole GO:0072665 1 0.011
cell substrate junction assembly GO:0007044 2 0.011
regulation of neurotransmitter secretion GO:0046928 1 0.011
regulation of circadian rhythm GO:0042752 4 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
female meiosis chromosome segregation GO:0016321 1 0.011
growth GO:0040007 174 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
Fly
immune system development GO:0002520 191 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
regulation of cellular component size GO:0032535 30 0.011
Fly
regulation of nucleoside metabolic process GO:0009118 2 0.011
single organism membrane fusion GO:0044801 2 0.011
lymphocyte proliferation GO:0046651 1 0.011
muscle structure development GO:0061061 196 0.011
regulation of neuronal synaptic plasticity GO:0048168 1 0.011
single organismal cell cell adhesion GO:0016337 29 0.011
mitotic cytokinesis GO:0000281 3 0.011
trabecula formation GO:0060343 2 0.011
nucleic acid templated transcription GO:0097659 181 0.010
establishment of spindle localization GO:0051293 12 0.010
small molecule catabolic process GO:0044282 3 0.010
glucose import GO:0046323 2 0.010
internal protein amino acid acetylation GO:0006475 2 0.010
phosphorus metabolic process GO:0006793 109 0.010
Fly
regulation of reactive oxygen species metabolic process GO:2000377 2 0.010
protein polyubiquitination GO:0000209 4 0.010
multi organism reproductive process GO:0044703 36 0.010
Mouse Fly
cellular carbohydrate metabolic process GO:0044262 4 0.010
phagosome maturation GO:0090382 1 0.010
regulation of cell substrate adhesion GO:0010810 1 0.010
regulation of striated muscle contraction GO:0006942 2 0.010
regulation of macromolecule biosynthetic process GO:0010556 225 0.010
rna metabolic process GO:0016070 219 0.010
b cell activation GO:0042113 2 0.010
mononuclear cell proliferation GO:0032943 1 0.010
regulation of systemic arterial blood pressure GO:0003073 1 0.010
phosphorylation GO:0016310 69 0.010
Fly
oocyte axis specification GO:0007309 5 0.010
leukocyte homeostasis GO:0001776 2 0.010
cellular macromolecule localization GO:0070727 21 0.010
negative regulation of protein localization to nucleus GO:1900181 2 0.010
regulation of nervous system development GO:0051960 90 0.010

capza1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.061
nervous system disease DOID:863 0 0.020
connective tissue disease DOID:65 0 0.011
bone disease DOID:0080001 0 0.011
bone development disease DOID:0080006 0 0.011
musculoskeletal system disease DOID:17 0 0.011