Danio rerio

30 known processes

ccm2

cerebral cavernous malformation 2

(Aliases: si:dkeyp-86f6.1,zgc:110233,vtn,MGC110233,valentine)

ccm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vasculature development GO:0001944 278 0.990
blood vessel morphogenesis GO:0048514 216 0.968
heart development GO:0007507 313 0.953
heart jogging GO:0003146 40 0.930
septum transversum development GO:0003343 4 0.904
blood vessel development GO:0001568 246 0.901
response to fluid shear stress GO:0034405 2 0.870
endodermal cell fate determination GO:0007493 2 0.778
negative regulation of calcium dependent cell cell adhesion GO:0046588 1 0.735
cardiac atrium development GO:0003230 4 0.731
heart morphogenesis GO:0003007 156 0.641
regulation of calcium dependent cell cell adhesion GO:0046586 1 0.612
venous blood vessel development GO:0060841 9 0.607
Mouse
central nervous system formation GO:0021556 1 0.604
larval development GO:0002164 2 0.548
caudal fin development GO:0033336 9 0.542
regulation of endothelial cell proliferation GO:0001936 1 0.541
cellular component movement GO:0006928 335 0.539
convergent extension involved in gastrulation GO:0060027 71 0.512
appendage development GO:0048736 80 0.503
cellular component morphogenesis GO:0032989 336 0.494
notochord development GO:0030903 54 0.494
regulation of multicellular organismal process GO:0051239 277 0.493
regulation of blood vessel size GO:0050880 2 0.478
lymph vessel morphogenesis GO:0036303 25 0.473
artery development GO:0060840 22 0.471
ameboidal type cell migration GO:0001667 143 0.461
regionalization GO:0003002 274 0.445
epithelial tube morphogenesis GO:0060562 148 0.437
tube morphogenesis GO:0035239 349 0.428
regulation of tube size GO:0035150 2 0.427
liver development GO:0001889 96 0.423
determination of dorsal identity GO:0048263 13 0.420
cell motility GO:0048870 244 0.414
negative regulation of cellular process GO:0048523 283 0.407
morphogenesis of an epithelium GO:0002009 333 0.402
cell morphogenesis GO:0000902 289 0.401
regulation of signaling GO:0023051 235 0.395
proepicardium development GO:0003342 4 0.394
vasculogenesis GO:0001570 41 0.394
hemopoiesis GO:0030097 183 0.391
lymph vessel development GO:0001945 27 0.389
gene expression GO:0010467 252 0.387
pericardium development GO:0060039 1 0.387
Mouse
patterning of blood vessels GO:0001569 15 0.385
determination of left right asymmetry in nervous system GO:0035545 4 0.385
determination of ventral identity GO:0048264 21 0.376
fin morphogenesis GO:0033334 53 0.360
regulation of biological quality GO:0065008 263 0.349
dorsal ventral pattern formation GO:0009953 125 0.348
determination of left right asymmetry in diencephalon GO:0035462 4 0.348
cellular component assembly GO:0022607 170 0.340
positive regulation of endothelial cell proliferation GO:0001938 1 0.340
organelle assembly GO:0070925 110 0.337
regulation of vasculature development GO:1901342 33 0.336
embryonic heart tube morphogenesis GO:0003143 108 0.325
hematopoietic or lymphoid organ development GO:0048534 191 0.322
odontogenesis of dentin containing tooth GO:0042475 1 0.313
cell cell adhesion GO:0098609 6 0.311
enzyme linked receptor protein signaling pathway GO:0007167 106 0.309
endothelial cell migration GO:0043542 19 0.308
positive regulation of synapse assembly GO:0051965 1 0.304
stem cell differentiation GO:0048863 117 0.304
epithelial cell migration GO:0010631 25 0.296
lymphangiogenesis GO:0001946 25 0.290
skeletal system development GO:0001501 181 0.289
cellular biosynthetic process GO:0044249 286 0.281
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.280
embryonic organ development GO:0048568 381 0.279
regulation of developmental process GO:0050793 247 0.275
circulatory system process GO:0003013 87 0.274
locomotion GO:0040011 313 0.267
immune system process GO:0002376 241 0.267
lateral inhibition GO:0046331 1 0.267
protein complex subunit organization GO:0071822 46 0.266
immune system development GO:0002520 191 0.266
aorta development GO:0035904 4 0.262
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.260
medial fin development GO:0033338 16 0.259
tissue migration GO:0090130 37 0.256
embryonic hemopoiesis GO:0035162 53 0.242
negative regulation of epithelial cell migration GO:0010633 1 0.241
aorta morphogenesis GO:0035909 3 0.240
medial fin morphogenesis GO:0035141 14 0.236
nucleocytoplasmic transport GO:0006913 4 0.233
digestive tract morphogenesis GO:0048546 231 0.231
venous blood vessel morphogenesis GO:0048845 3 0.228
Mouse
notochord morphogenesis GO:0048570 17 0.220
sprouting angiogenesis GO:0002040 53 0.218
regulation of multicellular organismal development GO:2000026 223 0.218
macromolecular complex assembly GO:0065003 35 0.210
negative regulation of angiogenesis GO:0016525 7 0.208
synaptic growth at neuromuscular junction GO:0051124 2 0.207
angiogenesis GO:0001525 158 0.203
regulation of epithelial cell proliferation GO:0050678 3 0.202
determination of dorsal ventral asymmetry GO:0048262 34 0.201
endothelial cell proliferation GO:0001935 11 0.199
epithelium migration GO:0090132 25 0.198
hematopoietic stem cell differentiation GO:0060218 20 0.198
cytoskeleton organization GO:0007010 96 0.196
mesenchyme development GO:0060485 127 0.194
organic substance biosynthetic process GO:1901576 289 0.190
cilium organization GO:0044782 71 0.185
system process GO:0003008 185 0.185
cellular protein metabolic process GO:0044267 129 0.184
connective tissue development GO:0061448 99 0.183
protein homooligomerization GO:0051260 3 0.180
cell migration GO:0016477 237 0.178
cell surface receptor signaling pathway GO:0007166 325 0.176
fin development GO:0033333 77 0.175
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.174
axon development GO:0061564 166 0.174
protein complex biogenesis GO:0070271 30 0.173
brain development GO:0007420 293 0.171
determination of left right symmetry GO:0007368 179 0.171
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.170
regulation of rna metabolic process GO:0051252 224 0.169
heart looping GO:0001947 94 0.169
localization of cell GO:0051674 244 0.168
embryo development ending in birth or egg hatching GO:0009792 271 0.166
Mouse
central nervous system development GO:0007417 387 0.166
diencephalon development GO:0021536 58 0.163
cellular nitrogen compound metabolic process GO:0034641 290 0.159
regulation of response to stimulus GO:0048583 269 0.159
regulation of neural precursor cell proliferation GO:2000177 3 0.158
regulation of macromolecule biosynthetic process GO:0010556 225 0.156
embryonic heart tube development GO:0035050 133 0.155
cell projection organization GO:0030030 284 0.153
protein metabolic process GO:0019538 183 0.153
cellular component assembly involved in morphogenesis GO:0010927 107 0.153
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.150
regulation of cellular response to growth factor stimulus GO:0090287 35 0.150
left right pattern formation GO:0060972 19 0.147
regulation of anatomical structure morphogenesis GO:0022603 130 0.147
dorsal convergence GO:0060030 14 0.141
regulation of nucleic acid templated transcription GO:1903506 213 0.141
regulation of transcription dna templated GO:0006355 213 0.137
negative regulation of biological process GO:0048519 304 0.136
embryonic appendage morphogenesis GO:0035113 30 0.136
spindle assembly involved in mitosis GO:0090307 1 0.136
caudal fin morphogenesis GO:0035143 7 0.136
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.136
tissue remodeling GO:0048771 4 0.133
lateral mesoderm development GO:0048368 23 0.132
signal transduction GO:0007165 455 0.131
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.130
ventricular cardiac muscle tissue development GO:0003229 3 0.129
regulation of extent of cell growth GO:0061387 29 0.129
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.128
inner ear development GO:0048839 126 0.125
Mouse
hepaticobiliary system development GO:0061008 98 0.124
macromolecule localization GO:0033036 54 0.121
mesoderm development GO:0007498 88 0.119
peptidyl serine phosphorylation GO:0018105 1 0.119
regulation of angiogenesis GO:0045765 26 0.118
cardiac atrium morphogenesis GO:0003209 2 0.116
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.115
cellular macromolecule metabolic process GO:0044260 391 0.115
regulation of signal transduction GO:0009966 225 0.114
organic cyclic compound biosynthetic process GO:1901362 223 0.113
positive regulation of cellular component biogenesis GO:0044089 3 0.112
single organism cell adhesion GO:0098602 29 0.112
vascular process in circulatory system GO:0003018 6 0.112
cellular protein catabolic process GO:0044257 4 0.111
regulation of localization GO:0032879 104 0.111
developmental growth involved in morphogenesis GO:0060560 86 0.108
blood circulation GO:0008015 87 0.108
nucleic acid templated transcription GO:0097659 181 0.108
regulation of nucleocytoplasmic transport GO:0046822 2 0.107
nucleobase containing compound biosynthetic process GO:0034654 205 0.106
embryonic organ morphogenesis GO:0048562 274 0.104
embryonic heart tube left right pattern formation GO:0060971 5 0.104
cilium morphogenesis GO:0060271 85 0.101
response to chemical GO:0042221 320 0.101
endothelium development GO:0003158 25 0.100
Mouse
regulation of blood pressure GO:0008217 1 0.099
endothelial cell development GO:0001885 12 0.097
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.096
chordate embryonic development GO:0043009 271 0.094
Mouse
response to organic substance GO:0010033 153 0.094
endodermal cell differentiation GO:0035987 19 0.093
sequestering of calcium ion GO:0051208 3 0.088
negative regulation of innate immune response GO:0045824 2 0.088
nuclear export GO:0051168 1 0.088
protein localization to nucleus GO:0034504 3 0.088
rna metabolic process GO:0016070 219 0.088
organelle organization GO:0006996 227 0.087
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.087
embryonic medial fin morphogenesis GO:0035122 6 0.086
germ line stem cell maintenance GO:0030718 2 0.086
biosynthetic process GO:0009058 294 0.085
stem cell development GO:0048864 82 0.084
regulation of gene expression GO:0010468 265 0.084
retina development in camera type eye GO:0060041 146 0.084
negative regulation of epithelial cell proliferation GO:0050680 1 0.084
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.082
convergent extension GO:0060026 118 0.082
regulation of neuron differentiation GO:0045664 56 0.079
positive regulation of catabolic process GO:0009896 4 0.079
negative regulation of endothelial cell migration GO:0010596 1 0.078
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.078
regulation of cell differentiation GO:0045595 142 0.078
epithelial cell differentiation GO:0030855 116 0.077
Mouse
regulation of axon extension GO:0030516 24 0.077
protein modification process GO:0036211 100 0.077
cellular response to oxygen levels GO:0071453 1 0.076
nucleic acid metabolic process GO:0090304 244 0.076
regulation of anatomical structure size GO:0090066 33 0.076
determination of bilateral symmetry GO:0009855 204 0.075
determination of heart left right asymmetry GO:0061371 117 0.075
regulation of multicellular organism growth GO:0040014 4 0.075
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.075
stem cell maintenance GO:0019827 4 0.074
regulation of establishment of cell polarity GO:2000114 1 0.074
regulation of retina development in camera type eye GO:1902866 2 0.074
cell morphogenesis involved in differentiation GO:0000904 195 0.073
rna biosynthetic process GO:0032774 181 0.073
regulation of nitrogen compound metabolic process GO:0051171 251 0.073
neuron differentiation GO:0030182 353 0.071
heterocycle biosynthetic process GO:0018130 215 0.071
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.070
neuromuscular synaptic transmission GO:0007274 2 0.069
multicellular organism growth GO:0035264 4 0.068
Mouse
ventral spinal cord interneuron fate commitment GO:0060579 3 0.067
fin regeneration GO:0031101 51 0.066
regulation of cell migration GO:0030334 40 0.066
intracellular transport GO:0046907 32 0.066
bmp signaling pathway GO:0030509 52 0.066
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.066
pericardium morphogenesis GO:0003344 1 0.066
regulation of systemic arterial blood pressure GO:0003073 1 0.066
proteasomal protein catabolic process GO:0010498 2 0.065
head development GO:0060322 303 0.064
protein import into nucleus GO:0006606 3 0.064
positive regulation of transport GO:0051050 2 0.063
heterocycle metabolic process GO:0046483 290 0.062
cellular response to chemical stimulus GO:0070887 157 0.061
regulation of epithelial cell migration GO:0010632 5 0.061
macromolecule biosynthetic process GO:0009059 227 0.061
post embryonic organ development GO:0048569 4 0.061
neuron projection extension GO:1990138 45 0.060
embryonic skeletal system development GO:0048706 97 0.059
regulation of blood circulation GO:1903522 32 0.059
organic substance transport GO:0071702 58 0.059
neuron projection development GO:0031175 180 0.059
regulation of biosynthetic process GO:0009889 250 0.058
cell part morphogenesis GO:0032990 246 0.058
regulation of bmp signaling pathway GO:0030510 39 0.058
stem cell division GO:0017145 1 0.058
protein complex assembly GO:0006461 30 0.056
cellular localization GO:0051641 97 0.056
regulation of protein catabolic process GO:0042176 1 0.056
cellular nitrogen compound biosynthetic process GO:0044271 218 0.055
regulation of cellular biosynthetic process GO:0031326 245 0.055
maintenance of location GO:0051235 4 0.055
pronephros development GO:0048793 69 0.055
protein import GO:0017038 3 0.054
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.054
homeostatic process GO:0042592 142 0.054
regulation of macromolecule metabolic process GO:0060255 317 0.054
sensory organ development GO:0007423 393 0.053
Mouse
endodermal cell fate commitment GO:0001711 18 0.053
generation of neurons GO:0048699 385 0.053
aromatic compound biosynthetic process GO:0019438 217 0.053
blood vessel endothelial cell migration GO:0043534 18 0.052
odontogenesis GO:0042476 9 0.052
meiotic nuclear division GO:0007126 4 0.051
cellular component disassembly GO:0022411 1 0.051
regulation of locomotion GO:0040012 55 0.050
dorsal aorta morphogenesis GO:0035912 3 0.050
single organism metabolic process GO:0044710 217 0.050
specification of symmetry GO:0009799 204 0.050
cell proliferation GO:0008283 80 0.049
forebrain development GO:0030900 96 0.049
regeneration GO:0031099 91 0.047
endothelial cell differentiation GO:0045446 20 0.047
Mouse
regulation of establishment of protein localization GO:0070201 4 0.047
negative regulation of apoptotic process GO:0043066 55 0.047
organism emergence from protective structure GO:0071684 4 0.046
regulation of cellular component organization GO:0051128 86 0.046
cardiac chamber development GO:0003205 19 0.046
axon extension GO:0048675 45 0.046
regulation of cellular component movement GO:0051270 55 0.046
cellular component biogenesis GO:0044085 178 0.046
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.044
regulation of protein binding GO:0043393 3 0.044
cell projection morphogenesis GO:0048858 244 0.044
nucleobase containing compound metabolic process GO:0006139 274 0.044
negative regulation of programmed cell death GO:0043069 58 0.043
cellular response to extracellular stimulus GO:0031668 2 0.043
macromolecular complex disassembly GO:0032984 1 0.043
hatching GO:0035188 4 0.042
regulation of neurogenesis GO:0050767 87 0.042
regulation of protein transport GO:0051223 3 0.042
reactive oxygen species biosynthetic process GO:1903409 1 0.042
cell migration involved in sprouting angiogenesis GO:0002042 8 0.041
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.041
calcium ion import GO:0070509 4 0.041
urogenital system development GO:0001655 97 0.041
macromolecular complex subunit organization GO:0043933 74 0.041
multicellular organismal reproductive process GO:0048609 35 0.040
cellular protein modification process GO:0006464 100 0.040
cellular response to growth factor stimulus GO:0071363 39 0.040
regulation of cytoplasmic transport GO:1903649 4 0.040
regulation of endothelial cell differentiation GO:0045601 3 0.040
regulation of glucose transport GO:0010827 1 0.040
regulation of metabolic process GO:0019222 359 0.040
regulation of binding GO:0051098 3 0.040
tissue regeneration GO:0042246 74 0.039
transcription dna templated GO:0006351 181 0.038
axon guidance GO:0007411 86 0.038
response to stress GO:0006950 263 0.038
positive regulation of epithelial cell migration GO:0010634 2 0.038
single organismal cell cell adhesion GO:0016337 29 0.038
nuclear transport GO:0051169 4 0.037
aging GO:0007568 2 0.037
protein targeting to nucleus GO:0044744 3 0.037
embryonic viscerocranium morphogenesis GO:0048703 52 0.037
embryonic caudal fin morphogenesis GO:0035124 3 0.037
segmentation GO:0035282 97 0.037
regulation of primary metabolic process GO:0080090 311 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.036
regulation of cell motility GO:2000145 46 0.036
positive regulation of biological process GO:0048518 253 0.036
positive regulation of epithelial cell proliferation GO:0050679 1 0.036
transcription from rna polymerase ii promoter GO:0006366 80 0.036
cardiac muscle tissue morphogenesis GO:0055008 7 0.036
regulation of synapse organization GO:0050807 3 0.035
actin cytoskeleton organization GO:0030036 63 0.035
microtubule polymerization or depolymerization GO:0031109 3 0.035
eye development GO:0001654 277 0.035
regulation of rna biosynthetic process GO:2001141 213 0.035
regulation of system process GO:0044057 40 0.035
taxis GO:0042330 109 0.035
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 6 0.035
regulation of cell size GO:0008361 29 0.035
digestive system development GO:0055123 289 0.034
positive regulation of nervous system development GO:0051962 25 0.034
phosphorus metabolic process GO:0006793 109 0.034
membrane fusion GO:0061025 2 0.034
nitric oxide biosynthetic process GO:0006809 2 0.034
kidney development GO:0001822 92 0.033
formation of primary germ layer GO:0001704 62 0.033
single organism localization GO:1902578 225 0.033
negative regulation of vasculature development GO:1901343 8 0.033
cytosolic calcium ion transport GO:0060401 3 0.033
regulation of meiotic cell cycle GO:0051445 1 0.033
neuroblast proliferation GO:0007405 2 0.032
calcium ion transport into cytosol GO:0060402 3 0.032
exocytosis GO:0006887 1 0.032
regulation of endothelial cell migration GO:0010594 5 0.032
fat soluble vitamin metabolic process GO:0006775 4 0.032
cellular macromolecule biosynthetic process GO:0034645 224 0.032
regulation of proteolysis GO:0030162 24 0.032
response to abiotic stimulus GO:0009628 122 0.031
regulation of cellular metabolic process GO:0031323 320 0.031
positive regulation of neural precursor cell proliferation GO:2000179 1 0.031
blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 4 0.031
transport GO:0006810 220 0.031
medulla oblongata development GO:0021550 4 0.031
regulation of cell proliferation GO:0042127 37 0.031
dorsal aorta development GO:0035907 4 0.031
proteolysis GO:0006508 38 0.030
negative regulation of endopeptidase activity GO:0010951 10 0.030
response to organic cyclic compound GO:0014070 51 0.030
spindle assembly GO:0051225 2 0.030
anterior posterior pattern specification GO:0009952 152 0.030
actomyosin structure organization GO:0031032 53 0.029
regulation of protein localization to nucleus GO:1900180 2 0.029
histone modification GO:0016570 20 0.029
endocardial cushion formation GO:0003272 2 0.029
negative regulation of cell death GO:0060548 60 0.029
regulation of protein import into nucleus GO:0042306 2 0.029
neural tube development GO:0021915 62 0.028
single organism nuclear import GO:1902593 3 0.028
protein oligomerization GO:0051259 7 0.028
internal protein amino acid acetylation GO:0006475 2 0.028
neural crest cell differentiation GO:0014033 72 0.028
developmental cell growth GO:0048588 52 0.028
positive regulation of cytokine production GO:0001819 2 0.027
neuron development GO:0048666 262 0.027
gland development GO:0048732 143 0.027
negative regulation of immune response GO:0050777 2 0.027
smooth muscle contraction GO:0006939 2 0.027
positive regulation of response to stimulus GO:0048584 80 0.027
mesoderm formation GO:0001707 43 0.027
cartilage development GO:0051216 96 0.027
negative regulation of cell adhesion GO:0007162 6 0.027
negative regulation of defense response GO:0031348 2 0.026
actin filament organization GO:0007015 15 0.026
cellular response to external stimulus GO:0071496 2 0.026
mesoderm morphogenesis GO:0048332 51 0.026
single organism organelle organization GO:1902589 199 0.026
lymphoid lineage cell migration into thymus GO:0097535 4 0.026
camera type eye development GO:0043010 222 0.026
positive regulation of multicellular organismal process GO:0051240 52 0.026
regulation of synapse assembly GO:0051963 3 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
regulation of cell growth GO:0001558 29 0.025
positive regulation of signal transduction GO:0009967 56 0.025
positive regulation of cellular catabolic process GO:0031331 3 0.025
regulation of metal ion transport GO:0010959 4 0.025
macromolecule catabolic process GO:0009057 15 0.025
wound healing GO:0042060 90 0.025
germ line stem cell division GO:0042078 1 0.025
microtubule depolymerization GO:0007019 1 0.025
gastrulation GO:0007369 208 0.025
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.025
skeletal muscle thin filament assembly GO:0030240 4 0.024
regulation of sequestering of calcium ion GO:0051282 4 0.024
protein depolymerization GO:0051261 1 0.024
positive regulation of blood circulation GO:1903524 2 0.024
amine metabolic process GO:0009308 2 0.024
apoptotic signaling pathway GO:0097190 23 0.024
protein acetylation GO:0006473 2 0.024
melanocyte apoptotic process GO:1902362 2 0.024
regulation of calcium ion transport GO:0051924 2 0.024
gene silencing by rna GO:0031047 4 0.023
neuron projection morphogenesis GO:0048812 161 0.023
macromolecule modification GO:0043412 111 0.023
negative regulation of multicellular organismal process GO:0051241 69 0.023
cytokinesis GO:0000910 3 0.023
negative regulation of protein kinase activity GO:0006469 4 0.023
posttranscriptional gene silencing GO:0016441 3 0.023
negative regulation of metabolic process GO:0009892 86 0.022
spinal cord development GO:0021510 46 0.022
divalent inorganic cation homeostasis GO:0072507 22 0.022
ribosomal small subunit biogenesis GO:0042274 2 0.022
endocardial cushion morphogenesis GO:0003203 3 0.022
sodium ion transmembrane transport GO:0035725 21 0.022
cell migration involved in gastrulation GO:0042074 79 0.022
regulation of heart contraction GO:0008016 32 0.021
maternal determination of anterior posterior axis embryo GO:0008358 4 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.021
biological adhesion GO:0022610 40 0.021
vacuole organization GO:0007033 9 0.021
positive regulation of bmp signaling pathway GO:0030513 10 0.021
endoderm development GO:0007492 49 0.021
regulation of molecular function GO:0065009 70 0.021
protein dephosphorylation GO:0006470 3 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.021
embryonic skeletal system morphogenesis GO:0048704 93 0.021
cellular response to endogenous stimulus GO:0071495 68 0.021
retina vasculature development in camera type eye GO:0061298 2 0.021
fat soluble vitamin biosynthetic process GO:0042362 2 0.020
xanthophore differentiation GO:0050936 3 0.020
positive regulation of secretion GO:0051047 1 0.020
regulation of apoptotic process GO:0042981 98 0.020
cellular ketone metabolic process GO:0042180 11 0.020
peptidyl lysine acetylation GO:0018394 2 0.020
negative regulation of cell migration GO:0030336 17 0.020
phagocytosis GO:0006909 3 0.020
microtubule organizing center organization GO:0031023 1 0.020
coenzyme biosynthetic process GO:0009108 2 0.020
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 10 0.020
regulation of intracellular signal transduction GO:1902531 57 0.020
regulation of blood vessel endothelial cell migration GO:0043535 5 0.020
centrosome organization GO:0051297 1 0.020
regulation of microtubule depolymerization GO:0031114 1 0.020
endoderm formation GO:0001706 29 0.020
meiotic spindle organization GO:0000212 1 0.020
cilium assembly GO:0042384 58 0.020
branching morphogenesis of an epithelial tube GO:0048754 15 0.020
cellular response to nutrient levels GO:0031669 2 0.020
regulation of biomineral tissue development GO:0070167 2 0.020
appendage morphogenesis GO:0035107 56 0.019
vitamin biosynthetic process GO:0009110 2 0.019
digestive tract development GO:0048565 265 0.019
mesenchymal cell development GO:0014031 78 0.019
regulation of protein depolymerization GO:1901879 1 0.019
defense response to fungus GO:0050832 2 0.019
rna modification GO:0009451 2 0.019
cell projection assembly GO:0030031 64 0.019
response to copper ion GO:0046688 13 0.019
establishment or maintenance of cell polarity GO:0007163 29 0.019
regulation of microtubule cytoskeleton organization GO:0070507 3 0.019
negative regulation of cell cell adhesion GO:0022408 6 0.019
internal peptidyl lysine acetylation GO:0018393 2 0.019
regulation of cytokine production GO:0001817 3 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
negative regulation of kinase activity GO:0033673 4 0.018
negative regulation of blood vessel morphogenesis GO:2000181 8 0.018
positive regulation of glial cell proliferation GO:0060252 1 0.018
cation homeostasis GO:0055080 33 0.018
response to external biotic stimulus GO:0043207 97 0.018
cell type specific apoptotic process GO:0097285 22 0.018
cell growth GO:0016049 57 0.018

ccm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.149
immune system disease DOID:2914 0 0.052
cardiovascular system disease DOID:1287 0 0.029
nervous system disease DOID:863 0 0.022
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
congenital hypoplastic anemia DOID:1342 0 0.018
diamond blackfan anemia DOID:1339 0 0.018
aplastic anemia DOID:12449 0 0.018