Danio rerio

0 known processes

cdc45

CDC45 cell division cycle 45 homolog (S. cerevisiae)

(Aliases: zgc:56264,cdc45l,wu:fi05h01)

cdc45 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
double strand break repair via homologous recombination GO:0000724 1 0.743
recombinational repair GO:0000725 1 0.324
regulation of multicellular organism growth GO:0040014 4 0.290
double strand break repair GO:0006302 3 0.221
cellular nitrogen compound metabolic process GO:0034641 290 0.162
organic cyclic compound metabolic process GO:1901360 301 0.160
dna biosynthetic process GO:0071897 3 0.159
meiosis i GO:0007127 1 0.159
centrosome organization GO:0051297 1 0.154
meiotic cell cycle process GO:1903046 3 0.153
meiotic nuclear division GO:0007126 4 0.132
response to stress GO:0006950 263 0.132
microtubule organizing center organization GO:0031023 1 0.124
positive regulation of dna metabolic process GO:0051054 1 0.122
regulation of cellular amino acid metabolic process GO:0006521 0 0.118
ribonucleoside monophosphate catabolic process GO:0009158 4 0.113
cellular aromatic compound metabolic process GO:0006725 295 0.111
nitrogen compound metabolic process GO:0006807 319 0.111
regulation of cellular amine metabolic process GO:0033238 0 0.110
multicellular organism growth GO:0035264 4 0.106
aging GO:0007568 2 0.090
mitotic recombination GO:0006312 2 0.086
heterocycle metabolic process GO:0046483 290 0.082
chromosome organization GO:0051276 31 0.082
negative regulation of cellular process GO:0048523 283 0.080
organic cyclic compound biosynthetic process GO:1901362 223 0.079
embryo development ending in birth or egg hatching GO:0009792 271 0.075
organic acid metabolic process GO:0006082 31 0.074
cellular amine metabolic process GO:0044106 2 0.073
dna metabolic process GO:0006259 27 0.073
amine metabolic process GO:0009308 2 0.071
response to alkaloid GO:0043279 2 0.071
cellular response to radiation GO:0071478 4 0.070
centrosome cycle GO:0007098 1 0.070
response to drug GO:0042493 3 0.069
peptidyl serine phosphorylation GO:0018105 1 0.069
cell cycle g2 m phase transition GO:0044839 4 0.067
single organism organelle organization GO:1902589 199 0.064
positive regulation of cellular catabolic process GO:0031331 3 0.064
regulation of cell cycle GO:0051726 52 0.060
response to chemical GO:0042221 320 0.060
regulation of mitotic cell cycle GO:0007346 25 0.060
single organism biosynthetic process GO:0044711 71 0.060
cellular amino acid metabolic process GO:0006520 7 0.060
nucleic acid metabolic process GO:0090304 244 0.058
small molecule metabolic process GO:0044281 77 0.058
cellular ketone metabolic process GO:0042180 11 0.058
meiotic chromosome segregation GO:0045132 3 0.057
protein acetylation GO:0006473 2 0.055
organonitrogen compound metabolic process GO:1901564 74 0.055
telomere maintenance GO:0000723 1 0.055
negative regulation of nuclear division GO:0051784 3 0.053
signal transduction GO:0007165 455 0.051
carboxylic acid metabolic process GO:0019752 22 0.051
regulation of cellular ketone metabolic process GO:0010565 7 0.051
oocyte maturation GO:0001556 4 0.050
purine nucleoside monophosphate catabolic process GO:0009128 4 0.050
cellular biosynthetic process GO:0044249 286 0.049
histone phosphorylation GO:0016572 2 0.048
dna catabolic process GO:0006308 1 0.048
nucleobase containing compound metabolic process GO:0006139 274 0.047
positive regulation of catabolic process GO:0009896 4 0.047
developmental growth GO:0048589 166 0.046
chromosome organization involved in meiosis GO:0070192 1 0.045
hatching GO:0035188 4 0.042
spermatid development GO:0007286 2 0.042
heterocycle biosynthetic process GO:0018130 215 0.041
biosynthetic process GO:0009058 294 0.040
regulation of nitrogen compound metabolic process GO:0051171 251 0.039
regulation of dna recombination GO:0000018 2 0.038
regulation of meiotic cell cycle GO:0051445 1 0.038
peptidyl serine modification GO:0018209 2 0.038
oxoacid metabolic process GO:0043436 31 0.037
cellular nitrogen compound biosynthetic process GO:0044271 218 0.037
cellular response to light stimulus GO:0071482 4 0.037
nucleocytoplasmic transport GO:0006913 4 0.037
organelle organization GO:0006996 227 0.036
regulation of response to stimulus GO:0048583 269 0.036
organic substance biosynthetic process GO:1901576 289 0.036
cell cycle GO:0007049 93 0.036
response to uv GO:0009411 3 0.035
establishment of protein localization to organelle GO:0072594 4 0.035
positive regulation of chromatin modification GO:1903310 1 0.034
positive regulation of cell cycle GO:0045787 3 0.034
maintenance of location GO:0051235 4 0.034
cellular response to chemical stimulus GO:0070887 157 0.033
response to radiation GO:0009314 51 0.033
protein acylation GO:0043543 3 0.033
single organism metabolic process GO:0044710 217 0.032
nuclear transport GO:0051169 4 0.032
negative regulation of biological process GO:0048519 304 0.032
peptidyl lysine acetylation GO:0018394 2 0.031
regulation of dna metabolic process GO:0051052 11 0.031
cytoskeleton organization GO:0007010 96 0.030
cellular component disassembly GO:0022411 1 0.030
ubiquitin dependent protein catabolic process GO:0006511 3 0.030
cytokinesis GO:0000910 3 0.029
cellular component assembly GO:0022607 170 0.029
atp catabolic process GO:0006200 4 0.028
positive regulation of biological process GO:0048518 253 0.028
regulation of transcription dna templated GO:0006355 213 0.028
specification of axis polarity GO:0065001 4 0.028
dna recombination GO:0006310 5 0.027
cell cycle arrest GO:0007050 1 0.027
positive regulation of chromosome organization GO:2001252 1 0.027
regulation of protein import into nucleus GO:0042306 2 0.027
positive regulation of histone modification GO:0031058 1 0.027
female meiotic division GO:0007143 2 0.027
cellular protein modification process GO:0006464 100 0.027
organism emergence from protective structure GO:0071684 4 0.027
g2 m transition of mitotic cell cycle GO:0000086 4 0.027
regulation of protein depolymerization GO:1901879 1 0.027
cellular response to stress GO:0033554 62 0.026
cellular macromolecule metabolic process GO:0044260 391 0.026
nucleobase containing compound biosynthetic process GO:0034654 205 0.026
response to organic substance GO:0010033 153 0.025
central nervous system development GO:0007417 387 0.025
signal transduction by p53 class mediator GO:0072331 13 0.024
b cell activation GO:0042113 2 0.024
response to abiotic stimulus GO:0009628 122 0.024
protein import into nucleus GO:0006606 3 0.024
macromolecular complex disassembly GO:0032984 1 0.024
sensory organ development GO:0007423 393 0.023
heart development GO:0007507 313 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
positive regulation of cellular process GO:0048522 201 0.023
cell morphogenesis GO:0000902 289 0.023
single organism nuclear import GO:1902593 3 0.023
cellular response to external stimulus GO:0071496 2 0.022
regulation of protein transport GO:0051223 3 0.022
protein metabolic process GO:0019538 183 0.022
male meiosis GO:0007140 2 0.022
eye development GO:0001654 277 0.021
intracellular mrna localization GO:0008298 1 0.021
rna localization GO:0006403 4 0.021
chromatin organization GO:0006325 22 0.021
cellular macromolecule biosynthetic process GO:0034645 224 0.021
negative regulation of dna metabolic process GO:0051053 4 0.021
regulation of signal transduction GO:0009966 225 0.021
reciprocal meiotic recombination GO:0007131 1 0.021
protein modification process GO:0036211 100 0.021
homeostatic process GO:0042592 142 0.021
regulation of rna metabolic process GO:0051252 224 0.020
reciprocal dna recombination GO:0035825 1 0.020
protein import GO:0017038 3 0.020
protein targeting to nucleus GO:0044744 3 0.020
internal protein amino acid acetylation GO:0006475 2 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
organelle fission GO:0048285 23 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
positive regulation of transport GO:0051050 2 0.020
regulation of microtubule cytoskeleton organization GO:0070507 3 0.019
nucleoside monophosphate catabolic process GO:0009125 4 0.019
regulation of biological quality GO:0065008 263 0.019
negative regulation of intracellular transport GO:0032387 3 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.019
regulation of mitotic cell cycle embryonic GO:0009794 2 0.019
negative regulation of mitosis GO:0045839 3 0.019
immune system development GO:0002520 191 0.019
cellular response to organic substance GO:0071310 105 0.018
regulation of binding GO:0051098 3 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
response to ionizing radiation GO:0010212 6 0.018
mitotic g2 m transition checkpoint GO:0044818 3 0.018
internal peptidyl lysine acetylation GO:0018393 2 0.018
phosphate containing compound metabolic process GO:0006796 108 0.018
lipid storage GO:0019915 1 0.018
peptidyl threonine modification GO:0018210 1 0.018
localization of cell GO:0051674 244 0.018
multi organism process GO:0051704 134 0.018
negative regulation of cytoplasmic transport GO:1903650 2 0.017
determination of bilateral symmetry GO:0009855 204 0.017
immune system process GO:0002376 241 0.017
negative regulation of cellular component organization GO:0051129 16 0.017
atp metabolic process GO:0046034 5 0.017
protein complex disassembly GO:0043241 1 0.017
macromolecule biosynthetic process GO:0009059 227 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
regulation of protein complex assembly GO:0043254 3 0.017
nuclear import GO:0051170 3 0.016
dna repair GO:0006281 6 0.016
anatomical structure homeostasis GO:0060249 36 0.016
modification dependent protein catabolic process GO:0019941 3 0.016
regulation of dna templated transcription in response to stress GO:0043620 0 0.016
macromolecular complex subunit organization GO:0043933 74 0.016
head development GO:0060322 303 0.016
peptidyl threonine phosphorylation GO:0018107 1 0.016
mitotic cell cycle GO:0000278 64 0.016
growth GO:0040007 174 0.016
adult behavior GO:0030534 2 0.015
cell cycle process GO:0022402 53 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
microtubule based process GO:0007017 60 0.015
positive regulation of cell activation GO:0050867 1 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.015
larval development GO:0002164 2 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
phosphorus metabolic process GO:0006793 109 0.014
positive regulation of developmental process GO:0051094 50 0.014
negative regulation of protein transport GO:0051224 3 0.014
positive regulation of metabolic process GO:0009893 108 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
regulation of dna replication GO:0006275 3 0.014
cellular response to endogenous stimulus GO:0071495 68 0.014
regulation of biosynthetic process GO:0009889 250 0.014
positive regulation of cellular biosynthetic process GO:0031328 68 0.014
nucleic acid templated transcription GO:0097659 181 0.014
phosphorylation GO:0016310 69 0.014
positive regulation of biosynthetic process GO:0009891 68 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
regulation of developmental process GO:0050793 247 0.014
chromatin modification GO:0016568 21 0.014
cell substrate adhesion GO:0031589 4 0.013
purine containing compound metabolic process GO:0072521 29 0.013
protein localization to nucleus GO:0034504 3 0.013
protein complex biogenesis GO:0070271 30 0.013
regionalization GO:0003002 274 0.013
cell surface receptor signaling pathway GO:0007166 325 0.013
immunoglobulin mediated immune response GO:0016064 3 0.013
regulation of protein catabolic process GO:0042176 1 0.013
regulation of reactive oxygen species metabolic process GO:2000377 2 0.013
g2 dna damage checkpoint GO:0031572 3 0.013
establishment of localization GO:0051234 244 0.013
lateral inhibition GO:0046331 1 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
developmental programmed cell death GO:0010623 4 0.013
gene expression GO:0010467 252 0.013
somatic cell dna recombination GO:0016444 1 0.013
negative regulation of signal transduction GO:0009968 94 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
embryonic organ development GO:0048568 381 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
intracellular signal transduction GO:0035556 85 0.012
regulation of cell communication GO:0010646 232 0.012
macromolecule modification GO:0043412 111 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.012
mitotic g2 dna damage checkpoint GO:0007095 3 0.012
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.012
negative regulation of transcription dna templated GO:0045892 45 0.012
regulation of protein complex disassembly GO:0043244 1 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
regulation of protein targeting GO:1903533 2 0.012
anterior posterior pattern specification GO:0009952 152 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
axis specification GO:0009798 43 0.012
cellular localization GO:0051641 97 0.012
immunoglobulin production GO:0002377 1 0.012
positive regulation of protein complex assembly GO:0031334 2 0.011
smooth muscle contraction GO:0006939 2 0.011
transcription dna templated GO:0006351 181 0.011
vasculature development GO:0001944 278 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
cell motility GO:0048870 244 0.011
locomotion GO:0040011 313 0.011
cellular component biogenesis GO:0044085 178 0.011
rna metabolic process GO:0016070 219 0.011
cell aging GO:0007569 2 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
mitotic nuclear division GO:0007067 18 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
regulation of cell cycle g2 m phase transition GO:1902749 4 0.011
reproductive process GO:0022414 40 0.011
spermatid differentiation GO:0048515 2 0.011
apoptotic process GO:0006915 116 0.011
response to endogenous stimulus GO:0009719 83 0.011
cellular response to dna damage stimulus GO:0006974 24 0.011
ras protein signal transduction GO:0007265 7 0.011
cell migration GO:0016477 237 0.011
response to light stimulus GO:0009416 46 0.011
behavior GO:0007610 74 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
fertilization GO:0009566 3 0.011
negative regulation of cell division GO:0051782 4 0.011
positive regulation of cell division GO:0051781 2 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
female gamete generation GO:0007292 14 0.010
regulation of cell activation GO:0050865 1 0.010
organelle assembly GO:0070925 110 0.010
regulation of rna biosynthetic process GO:2001141 213 0.010
cellular component morphogenesis GO:0032989 336 0.010

cdc45 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.062
disease of cellular proliferation DOID:14566 0 0.062
disease of anatomical entity DOID:7 0 0.056
organ system cancer DOID:0050686 0 0.048
thoracic cancer DOID:5093 0 0.039
nervous system disease DOID:863 0 0.025
breast cancer DOID:1612 0 0.017