Danio rerio

0 known processes

cdk7

cyclin-dependent kinase 7

(Aliases: MGC85821,zgc:85821)

cdk7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.491
sensory organ development GO:0007423 393 0.134
digestive tract development GO:0048565 265 0.108
stem cell proliferation GO:0072089 4 0.107
homeostatic process GO:0042592 142 0.104
gene expression GO:0010467 252 0.093
Human Yeast Rat Fly
viral process GO:0016032 1 0.092
organic substance biosynthetic process GO:1901576 289 0.085
Human Yeast Rat Fly
nucleobase containing compound metabolic process GO:0006139 274 0.084
Human Yeast Rat Fly
establishment of localization GO:0051234 244 0.081
maintenance of location GO:0051235 4 0.081
cellular aromatic compound metabolic process GO:0006725 295 0.079
Human Yeast Rat Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.077
Human Yeast Rat Fly
regulation of metabolic process GO:0019222 359 0.075
Human Yeast Fly
digestive system development GO:0055123 289 0.072
regulation of gene expression GO:0010468 265 0.070
Human Yeast
multi organism cellular process GO:0044764 2 0.067
signal transduction GO:0007165 455 0.065
organic cyclic compound metabolic process GO:1901360 301 0.064
Human Yeast Rat Fly
mitotic dna integrity checkpoint GO:0044774 4 0.060
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.059
heart development GO:0007507 313 0.058
generation of neurons GO:0048699 385 0.057
transport GO:0006810 220 0.056
cellular nitrogen compound metabolic process GO:0034641 290 0.053
Human Yeast Rat Fly
guanosine containing compound catabolic process GO:1901069 2 0.052
neuron development GO:0048666 262 0.050
nucleic acid metabolic process GO:0090304 244 0.049
Human Yeast Rat Fly
gastrulation GO:0007369 208 0.049
nucleocytoplasmic transport GO:0006913 4 0.049
nuclear import GO:0051170 3 0.048
aging GO:0007568 2 0.048
morphogenesis of an epithelium GO:0002009 333 0.047
nuclear transport GO:0051169 4 0.046
negative regulation of biological process GO:0048519 304 0.046
cell morphogenesis involved in differentiation GO:0000904 195 0.044
interspecies interaction between organisms GO:0044419 4 0.042
programmed cell death GO:0012501 119 0.042
Fly
single organism metabolic process GO:0044710 217 0.041
Human
small molecule metabolic process GO:0044281 77 0.041
Human
regulation of cell death GO:0010941 103 0.041
regulation of biological quality GO:0065008 263 0.041
regulation of signaling GO:0023051 235 0.041
regulation of protein localization to nucleus GO:1900180 2 0.041
cellular nitrogen compound biosynthetic process GO:0044271 218 0.040
Human Yeast Rat Fly
negative regulation of catabolic process GO:0009895 3 0.040
gtp metabolic process GO:0046039 4 0.040
g1 s transition of mitotic cell cycle GO:0000082 1 0.040
protein localization to nucleus GO:0034504 3 0.039
embryo development ending in birth or egg hatching GO:0009792 271 0.039
mitotic dna damage checkpoint GO:0044773 4 0.038
response to chemical GO:0042221 320 0.038
cell projection morphogenesis GO:0048858 244 0.038
guanosine containing compound metabolic process GO:1901068 4 0.037
regulation of cytokine production GO:0001817 3 0.037
cell death GO:0008219 121 0.036
Fly
cell cycle g1 s phase transition GO:0044843 1 0.036
urogenital system development GO:0001655 97 0.036
rna biosynthetic process GO:0032774 181 0.036
Human Yeast Rat Fly
gtp catabolic process GO:0006184 2 0.035
neuron differentiation GO:0030182 353 0.035
response to stress GO:0006950 263 0.035
digestive tract morphogenesis GO:0048546 231 0.035
cellular response to organic substance GO:0071310 105 0.035
nitrogen compound metabolic process GO:0006807 319 0.035
Human Yeast Rat Fly
regulation of cellular amine metabolic process GO:0033238 0 0.035
cellular protein metabolic process GO:0044267 129 0.034
Human Yeast Mouse Rat Fly
determination of left right symmetry GO:0007368 179 0.034
immune system process GO:0002376 241 0.034
macromolecule biosynthetic process GO:0009059 227 0.034
Human Yeast Rat Fly
specification of symmetry GO:0009799 204 0.034
positive regulation of catabolic process GO:0009896 4 0.033
regulation of cell communication GO:0010646 232 0.033
single organism transport GO:0044765 206 0.033
organelle fusion GO:0048284 3 0.033
rna metabolic process GO:0016070 219 0.033
Human Yeast Rat Fly
translational initiation GO:0006413 3 0.032
mitotic g2 dna damage checkpoint GO:0007095 3 0.032
cellular biosynthetic process GO:0044249 286 0.032
Human Yeast Rat Fly
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.031
heterocycle metabolic process GO:0046483 290 0.031
Human Yeast Rat Fly
response to external stimulus GO:0009605 264 0.030
cell migration GO:0016477 237 0.029
cellular aldehyde metabolic process GO:0006081 4 0.029
regulation of anatomical structure morphogenesis GO:0022603 130 0.029
positive regulation of transport GO:0051050 2 0.029
eye development GO:0001654 277 0.028
meiotic cell cycle process GO:1903046 3 0.028
mitotic g2 m transition checkpoint GO:0044818 3 0.027
determination of bilateral symmetry GO:0009855 204 0.027
transcription from rna polymerase ii promoter GO:0006366 80 0.027
Human Yeast Rat Fly
meiotic nuclear division GO:0007126 4 0.027
amine metabolic process GO:0009308 2 0.027
regulation of apoptotic process GO:0042981 98 0.026
death GO:0016265 121 0.026
Fly
cell morphogenesis GO:0000902 289 0.026
multi organism process GO:0051704 134 0.026
protein stabilization GO:0050821 2 0.026
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.026
neuroblast proliferation GO:0007405 2 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.026
organelle organization GO:0006996 227 0.026
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
positive regulation of cellular catabolic process GO:0031331 3 0.025
locomotion GO:0040011 313 0.025
blood vessel development GO:0001568 246 0.025
apoptotic process GO:0006915 116 0.025
regulation of blood vessel size GO:0050880 2 0.025
lipid storage GO:0019915 1 0.025
protein secretion GO:0009306 1 0.025
cell surface receptor signaling pathway GO:0007166 325 0.025
cellular response to chemical stimulus GO:0070887 157 0.024
protein acetylation GO:0006473 2 0.024
cell part morphogenesis GO:0032990 246 0.024
regulation of cell shape GO:0008360 1 0.024
vasculature development GO:0001944 278 0.024
cellular response to stress GO:0033554 62 0.024
regulation of meiotic cell cycle GO:0051445 1 0.024
neurological system process GO:0050877 62 0.024
inorganic ion transmembrane transport GO:0098660 57 0.024
stem cell division GO:0017145 1 0.024
periodic partitioning GO:0007365 1 0.023
g2 dna damage checkpoint GO:0031572 3 0.023
gene silencing by mirna GO:0035195 3 0.023
autophagy GO:0006914 4 0.023
regulation of inflammatory response GO:0050727 2 0.023
modification of morphology or physiology of other organism GO:0035821 4 0.023
single organism membrane fusion GO:0044801 2 0.023
single organism localization GO:1902578 225 0.023
negative regulation of signaling GO:0023057 96 0.022
head development GO:0060322 303 0.022
modification dependent protein catabolic process GO:0019941 3 0.022
single organism nuclear import GO:1902593 3 0.022
modulation by virus of host morphology or physiology GO:0019048 1 0.022
response to organic substance GO:0010033 153 0.022
multicellular organism growth GO:0035264 4 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
Human
negative regulation of cellular process GO:0048523 283 0.022
carboxylic acid metabolic process GO:0019752 22 0.022
positive regulation of programmed cell death GO:0043068 29 0.022
regulation of protein import into nucleus GO:0042306 2 0.022
oxoacid metabolic process GO:0043436 31 0.022
regulation of programmed cell death GO:0043067 101 0.022
negative regulation of cellular catabolic process GO:0031330 3 0.022
diterpenoid biosynthetic process GO:0016102 7 0.022
cellular component morphogenesis GO:0032989 336 0.021
epithelial tube morphogenesis GO:0060562 148 0.021
regulation of protein catabolic process GO:0042176 1 0.021
positive regulation of cell cycle GO:0045787 3 0.021
regulation of cellular component organization GO:0051128 86 0.021
ion transmembrane transport GO:0034220 91 0.021
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.021
system process GO:0003008 185 0.021
transmembrane transport GO:0055085 120 0.021
negative regulation of epithelial cell proliferation GO:0050680 1 0.020
biosynthetic process GO:0009058 294 0.020
Human Yeast Rat Fly
establishment of protein localization to organelle GO:0072594 4 0.020
regulation of nucleocytoplasmic transport GO:0046822 2 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.020
negative regulation of translation GO:0017148 1 0.020
stem cell maintenance GO:0019827 4 0.020
cellular ketone metabolic process GO:0042180 11 0.020
spermatid development GO:0007286 2 0.020
spermatid differentiation GO:0048515 2 0.019
regulation of molecular function GO:0065009 70 0.019
Fly
heart looping GO:0001947 94 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
Human Yeast
regulation of oxidative stress induced cell death GO:1903201 2 0.019
cytokinesis GO:0000910 3 0.019
cellular macromolecule metabolic process GO:0044260 391 0.019
Human Yeast Mouse Rat Fly
regulation of nucleotide catabolic process GO:0030811 2 0.019
cell proliferation GO:0008283 80 0.019
negative regulation of mitosis GO:0045839 3 0.019
embryonic cranial skeleton morphogenesis GO:0048701 90 0.019
cellular localization GO:0051641 97 0.019
response to wounding GO:0009611 116 0.019
cellular amine metabolic process GO:0044106 2 0.019
regulation of epithelial cell proliferation GO:0050678 3 0.018
cell projection organization GO:0030030 284 0.018
organic acid metabolic process GO:0006082 31 0.018
morphogenesis of an epithelial fold GO:0060571 1 0.018
cell death in response to oxidative stress GO:0036473 2 0.018
regulation of cellular protein catabolic process GO:1903362 1 0.018
cellular response to starvation GO:0009267 1 0.018
negative regulation of macromolecule metabolic process GO:0010605 76 0.018
developmental process involved in reproduction GO:0003006 27 0.018
regulation of organ growth GO:0046620 3 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
kidney development GO:0001822 92 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
localization of cell GO:0051674 244 0.017
ameboidal type cell migration GO:0001667 143 0.017
adult behavior GO:0030534 2 0.017
retinal metabolic process GO:0042574 3 0.017
endosomal transport GO:0016197 2 0.017
skeletal system morphogenesis GO:0048705 102 0.017
rho protein signal transduction GO:0007266 5 0.017
positive regulation of cytokine production GO:0001819 2 0.017
chromosome organization involved in meiosis GO:0070192 1 0.017
regulation of translational initiation GO:0006446 1 0.017
renal system development GO:0072001 94 0.017
golgi vesicle transport GO:0048193 3 0.016
macromolecule localization GO:0033036 54 0.016
leukocyte homeostasis GO:0001776 2 0.016
nucleobase containing compound catabolic process GO:0034655 15 0.016
Human
negative regulation of protein phosphorylation GO:0001933 4 0.016
intracellular signal transduction GO:0035556 85 0.016
positive regulation of muscle cell differentiation GO:0051149 1 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
mitotic cell cycle phase transition GO:0044772 9 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
nucleic acid templated transcription GO:0097659 181 0.016
Human Yeast Rat Fly
sensory organ morphogenesis GO:0090596 200 0.016
pericardium development GO:0060039 1 0.015
embryonic organ development GO:0048568 381 0.015
odontogenesis of dentin containing tooth GO:0042475 1 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
positive regulation of biological process GO:0048518 253 0.015
Human Yeast
regulation of cellular ketone metabolic process GO:0010565 7 0.015
regulation of developmental process GO:0050793 247 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
nucleobase containing small molecule metabolic process GO:0055086 32 0.015
Human
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.015
rna splicing GO:0008380 16 0.015
protein import into nucleus GO:0006606 3 0.015
protein metabolic process GO:0019538 183 0.015
Human Yeast Mouse Rat Fly
carbohydrate homeostasis GO:0033500 1 0.015
regulation of response to stimulus GO:0048583 269 0.015
skeletal system development GO:0001501 181 0.015
regulation of signal transduction GO:0009966 225 0.015
eye morphogenesis GO:0048592 144 0.014
protein targeting to nucleus GO:0044744 3 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
killing of cells in other organism involved in symbiotic interaction GO:0051883 1 0.014
cellular response to nutrient levels GO:0031669 2 0.014
taxis GO:0042330 109 0.014
positive regulation of cell killing GO:0031343 2 0.014
regulation of metal ion transport GO:0010959 4 0.014
multicellular organismal response to stress GO:0033555 2 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
neuron projection morphogenesis GO:0048812 161 0.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.014
internal protein amino acid acetylation GO:0006475 2 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
Human Yeast Fly
gland development GO:0048732 143 0.014
regulation of binding GO:0051098 3 0.014
regulation of wound healing GO:0061041 2 0.014
cellular response to external stimulus GO:0071496 2 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
positive regulation of apoptotic process GO:0043065 29 0.013
zymogen activation GO:0031638 3 0.013
regulation of ph GO:0006885 3 0.013
chemosensory behavior GO:0007635 1 0.013
positive regulation of secretion GO:0051047 1 0.013
organic substance transport GO:0071702 58 0.013
mitotic cell cycle process GO:1903047 48 0.013
Fly
negative regulation of protein kinase activity GO:0006469 4 0.013
regulation of transporter activity GO:0032409 2 0.013
regulation of rho protein signal transduction GO:0035023 2 0.013
regulation of neuronal synaptic plasticity GO:0048168 1 0.013
negative regulation of gene expression GO:0010629 65 0.013
negative regulation of apoptotic process GO:0043066 55 0.013
embryonic appendage morphogenesis GO:0035113 30 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.013
cellular response to light stimulus GO:0071482 4 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
multicellular organismal reproductive process GO:0048609 35 0.013
regulation of membrane potential GO:0042391 23 0.013
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
Human Yeast
axon development GO:0061564 166 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
reproductive process GO:0022414 40 0.012
embryonic limb morphogenesis GO:0030326 2 0.012
ion transport GO:0006811 114 0.012
tube morphogenesis GO:0035239 349 0.012
gamete generation GO:0007276 33 0.012
establishment of localization in cell GO:0051649 77 0.012
multicellular organismal signaling GO:0035637 22 0.012
secondary metabolic process GO:0019748 3 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
regulation of lipase activity GO:0060191 2 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
positive regulation of cell death GO:0010942 29 0.012
cell fate commitment GO:0045165 99 0.012
macromolecule modification GO:0043412 111 0.012
Human Yeast Mouse Rat Fly
negative regulation of multi organism process GO:0043901 3 0.012
protein import GO:0017038 3 0.012
muscle tissue development GO:0060537 110 0.012
regulation of protein transport GO:0051223 3 0.012
axonogenesis GO:0007409 152 0.012
regulation of receptor activity GO:0010469 2 0.012
neuron projection development GO:0031175 180 0.012
response to monosaccharide GO:0034284 3 0.012
dsrna fragmentation GO:0031050 1 0.012
negative regulation of nuclear division GO:0051784 3 0.012
cellular response to dsrna GO:0071359 1 0.012
eye photoreceptor cell development GO:0042462 30 0.012
central nervous system development GO:0007417 387 0.012
double strand break repair GO:0006302 3 0.012
single organism biosynthetic process GO:0044711 71 0.011
regulation of cell activation GO:0050865 1 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
germ cell development GO:0007281 22 0.011
cellular component movement GO:0006928 335 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
Human Yeast Rat Fly
cellular extravasation GO:0045123 1 0.011
mrna metabolic process GO:0016071 20 0.011
Yeast
exocytosis GO:0006887 1 0.011
cellular protein catabolic process GO:0044257 4 0.011
killing of cells of other organism GO:0031640 1 0.011
cation transport GO:0006812 81 0.011
chemotaxis GO:0006935 104 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
regulation of response to nutrient levels GO:0032107 1 0.011
regulation of protein targeting GO:1903533 2 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
Human Yeast
regulation of heart growth GO:0060420 2 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
Human Yeast
positive regulation of immune effector process GO:0002699 3 0.011
positive regulation of cellular component biogenesis GO:0044089 3 0.011
response to uv GO:0009411 3 0.011
primary neural tube formation GO:0014020 1 0.011
hormone transport GO:0009914 2 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.010
carboxylic acid biosynthetic process GO:0046394 12 0.010
positive regulation of cellular process GO:0048522 201 0.010
Human Yeast
phosphate containing compound metabolic process GO:0006796 108 0.010
Human Yeast Mouse Rat Fly
action potential GO:0001508 19 0.010
gene silencing by rna GO:0031047 4 0.010
membrane fusion GO:0061025 2 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.010
positive regulation of neuron death GO:1901216 1 0.010
negative regulation of cell communication GO:0010648 96 0.010
stem cell fate commitment GO:0048865 1 0.010
response to drug GO:0042493 3 0.010
interaction with host GO:0051701 4 0.010
camera type eye development GO:0043010 222 0.010
cell migration involved in gastrulation GO:0042074 79 0.010
negative regulation of cell death GO:0060548 60 0.010
regulation of reproductive process GO:2000241 4 0.010
determination of heart left right asymmetry GO:0061371 117 0.010
chemical homeostasis GO:0048878 49 0.010
cell division GO:0051301 20 0.010
inner ear development GO:0048839 126 0.010
negative regulation of mitotic cell cycle GO:0045930 11 0.010
cell projection assembly GO:0030031 64 0.010
response to ketone GO:1901654 1 0.010

cdk7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.044
inherited metabolic disorder DOID:655 0 0.044
lysosomal storage disease DOID:3211 0 0.027
disease of anatomical entity DOID:7 0 0.014
muscular disease DOID:0080000 0 0.012
musculoskeletal system disease DOID:17 0 0.012
disease of cellular proliferation DOID:14566 0 0.010