Danio rerio

6 known processes

cdt1

chromatin licensing and DNA replication factor 1

(Aliases: im:7158083,wu:fi38h09,fc37h07,wu:fc37h07)

cdt1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular catabolic process GO:0031330 3 0.411
modification dependent macromolecule catabolic process GO:0043632 3 0.399
cellular macromolecule metabolic process GO:0044260 391 0.376
Human Mouse Worm Fly
cellular protein catabolic process GO:0044257 4 0.360
regulation of protein ubiquitination GO:0031396 3 0.325
negative regulation of nuclear division GO:0051784 3 0.320
single organism organelle organization GO:1902589 199 0.317
Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.261
Human Mouse Worm Fly
regulation of metabolic process GO:0019222 359 0.259
Human Mouse
cellular biosynthetic process GO:0044249 286 0.252
Human Mouse Worm Fly
modification dependent protein catabolic process GO:0019941 3 0.250
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.219
regulation of meiotic cell cycle GO:0051445 1 0.218
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.211
mitotic cell cycle process GO:1903047 48 0.210
Fly
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.209
biosynthetic process GO:0009058 294 0.208
Human Mouse Worm Fly
ubiquitin dependent protein catabolic process GO:0006511 3 0.203
positive regulation of cell cycle GO:0045787 3 0.202
negative regulation of mitosis GO:0045839 3 0.176
mitotic cell cycle GO:0000278 64 0.176
regulation of cell cycle GO:0051726 52 0.168
Mouse
gene expression GO:0010467 252 0.164
mitotic dna integrity checkpoint GO:0044774 4 0.164
regulation of macromolecule metabolic process GO:0060255 317 0.163
Human Mouse
regulation of primary metabolic process GO:0080090 311 0.154
Human Mouse
organic substance biosynthetic process GO:1901576 289 0.150
Human Mouse Worm Fly
mitotic nuclear division GO:0007067 18 0.149
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.142
Human Mouse
negative regulation of mitotic cell cycle GO:0045930 11 0.141
regulation of gene expression GO:0010468 265 0.141
proteolysis GO:0006508 38 0.137
regulation of cellular metabolic process GO:0031323 320 0.137
Human Mouse
stem cell maintenance GO:0019827 4 0.127
cell cycle process GO:0022402 53 0.126
Human Mouse Fly
signal transduction GO:0007165 455 0.125
proteasomal protein catabolic process GO:0010498 2 0.122
cellular nitrogen compound metabolic process GO:0034641 290 0.120
Human Mouse Worm Fly
organic cyclic compound metabolic process GO:1901360 301 0.120
Human Mouse Worm Fly
rna biosynthetic process GO:0032774 181 0.119
somatic stem cell maintenance GO:0035019 1 0.105
regulation of proteolysis GO:0030162 24 0.105
response to external biotic stimulus GO:0043207 97 0.102
Fly
organelle assembly GO:0070925 110 0.099
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.098
heterocycle metabolic process GO:0046483 290 0.097
Human Mouse Worm Fly
larval development GO:0002164 2 0.097
Worm
single organism biosynthetic process GO:0044711 71 0.096
Mouse Fly
heart development GO:0007507 313 0.086
cellular nitrogen compound biosynthetic process GO:0044271 218 0.084
mitotic sister chromatid segregation GO:0000070 6 0.083
Fly
negative regulation of cellular process GO:0048523 283 0.078
organelle organization GO:0006996 227 0.074
Fly
negative regulation of catabolic process GO:0009895 3 0.073
regulation of rna biosynthetic process GO:2001141 213 0.073
g1 s transition of mitotic cell cycle GO:0000082 1 0.072
cell division GO:0051301 20 0.071
Fly
rna transport GO:0050658 2 0.070
dna biosynthetic process GO:0071897 3 0.066
negative regulation of cell cycle GO:0045786 14 0.066
digestive system development GO:0055123 289 0.065
cell cycle g1 s phase transition GO:0044843 1 0.065
positive regulation of cellular process GO:0048522 201 0.064
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.063
Human Mouse
negative regulation of biological process GO:0048519 304 0.063
regulation of macromolecule biosynthetic process GO:0010556 225 0.063
Human Mouse
negative regulation of proteolysis GO:0045861 10 0.062
nitrogen compound metabolic process GO:0006807 319 0.062
Human Mouse Worm Fly
negative regulation of chromosome organization GO:2001251 1 0.061
response to biotic stimulus GO:0009607 97 0.061
Fly
regulation of mitotic cell cycle GO:0007346 25 0.061
maintenance of location GO:0051235 4 0.060
regulation of chromosome segregation GO:0051983 1 0.058
single organism metabolic process GO:0044710 217 0.058
Mouse Fly
regulation of cell communication GO:0010646 232 0.057
death GO:0016265 121 0.056
chromosome organization GO:0051276 31 0.055
Fly
regulation of cell division GO:0051302 12 0.055
regulation of nucleocytoplasmic transport GO:0046822 2 0.050
generation of neurons GO:0048699 385 0.048
spindle assembly GO:0051225 2 0.047
stem cell development GO:0048864 82 0.047
nucleic acid metabolic process GO:0090304 244 0.046
Human Mouse Worm Fly
establishment of localization GO:0051234 244 0.046
regulation of transcription dna templated GO:0006355 213 0.045
cytokinesis GO:0000910 3 0.045
Fly
g2 m transition of mitotic cell cycle GO:0000086 4 0.045
chromosome segregation GO:0007059 12 0.045
Fly
negative regulation of cell cycle process GO:0010948 9 0.045
regulation of cellular protein catabolic process GO:1903362 1 0.044
protein complex assembly GO:0006461 30 0.044
transport GO:0006810 220 0.043
regulation of cytoplasmic transport GO:1903649 4 0.042
regulation of dna replication GO:0006275 3 0.040
Human Mouse
neuroblast differentiation GO:0014016 1 0.040
response to stress GO:0006950 263 0.040
positive regulation of biological process GO:0048518 253 0.040
aromatic compound biosynthetic process GO:0019438 217 0.039
cellular aromatic compound metabolic process GO:0006725 295 0.039
Human Mouse Worm Fly
sex determination GO:0007530 1 0.039
protein polyubiquitination GO:0000209 4 0.038
establishment of protein localization to organelle GO:0072594 4 0.038
regulation of catalytic activity GO:0050790 55 0.038
cellular component assembly GO:0022607 170 0.037
protein metabolic process GO:0019538 183 0.037
apoptotic process GO:0006915 116 0.037
regulation of cellular component organization GO:0051128 86 0.037
sister chromatid segregation GO:0000819 6 0.036
Fly
organelle fission GO:0048285 23 0.036
Fly
stem cell differentiation GO:0048863 117 0.036
striated muscle cell differentiation GO:0051146 129 0.036
rna metabolic process GO:0016070 219 0.035
nucleobase containing compound biosynthetic process GO:0034654 205 0.035
embryo development ending in birth or egg hatching GO:0009792 271 0.035
Worm
immune system development GO:0002520 191 0.035
regulation of protein transport GO:0051223 3 0.035
cellular component morphogenesis GO:0032989 336 0.035
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.035
transcription dna templated GO:0006351 181 0.035
protein localization to nucleus GO:0034504 3 0.034
organic cyclic compound biosynthetic process GO:1901362 223 0.034
cell cycle GO:0007049 93 0.033
mitotic metaphase plate congression GO:0007080 1 0.033
nucleocytoplasmic transport GO:0006913 4 0.033
cellular component assembly involved in morphogenesis GO:0010927 107 0.033
regulation of apoptotic process GO:0042981 98 0.033
protein modification process GO:0036211 100 0.031
regulation of intracellular protein transport GO:0033157 3 0.031
positive regulation of transport GO:0051050 2 0.031
regulation of protein import into nucleus GO:0042306 2 0.031
heterocycle biosynthetic process GO:0018130 215 0.030
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.030
Human Mouse
cell fate commitment GO:0045165 99 0.030
meiotic chromosome segregation GO:0045132 3 0.029
regulation of cell cycle phase transition GO:1901987 8 0.029
single organism nuclear import GO:1902593 3 0.029
negative regulation of gene expression GO:0010629 65 0.029
regulation of mitotic cell cycle phase transition GO:1901990 8 0.028
cellular response to stress GO:0033554 62 0.028
cell surface receptor signaling pathway GO:0007166 325 0.027
homeostatic process GO:0042592 142 0.027
meiotic cell cycle process GO:1903046 3 0.026
regulation of protein localization to nucleus GO:1900180 2 0.026
nuclear transport GO:0051169 4 0.026
stem cell fate commitment GO:0048865 1 0.026
transcription from rna polymerase ii promoter GO:0006366 80 0.026
chordate embryonic development GO:0043009 271 0.025
negative regulation of catalytic activity GO:0043086 21 0.025
protein targeting to nucleus GO:0044744 3 0.025
regulation of cell shape GO:0008360 1 0.025
gland development GO:0048732 143 0.025
negative regulation of dna metabolic process GO:0051053 4 0.025
regulation of nuclear division GO:0051783 9 0.025
response to abiotic stimulus GO:0009628 122 0.025
striated muscle cell development GO:0055002 108 0.024
negative regulation of macromolecule metabolic process GO:0010605 76 0.024
regulation of establishment of protein localization GO:0070201 4 0.024
digestive tract development GO:0048565 265 0.024
nucleic acid templated transcription GO:0097659 181 0.024
multi organism process GO:0051704 134 0.024
Fly
cytoskeleton organization GO:0007010 96 0.023
Fly
regulation of mitosis GO:0007088 9 0.023
muscle cell differentiation GO:0042692 139 0.023
cell cycle checkpoint GO:0000075 7 0.023
Human Mouse Fly
regulation of protein metabolic process GO:0051246 56 0.023
regulation of programmed cell death GO:0043067 101 0.023
immunoglobulin mediated immune response GO:0016064 3 0.023
immune system process GO:0002376 241 0.022
Fly
production of molecular mediator of immune response GO:0002440 2 0.022
nuclear import GO:0051170 3 0.022
negative regulation of signaling GO:0023057 96 0.022
positive regulation of metabolic process GO:0009893 108 0.022
cell projection assembly GO:0030031 64 0.022
cellular component biogenesis GO:0044085 178 0.022
cellular response to oxygen levels GO:0071453 1 0.022
regulation of protein catabolic process GO:0042176 1 0.022
pancreas development GO:0031016 84 0.022
positive regulation of cell division GO:0051781 2 0.022
response to drug GO:0042493 3 0.021
histone phosphorylation GO:0016572 2 0.021
macromolecular complex subunit organization GO:0043933 74 0.021
regulation of protein maturation GO:1903317 10 0.021
rna localization GO:0006403 4 0.021
tube morphogenesis GO:0035239 349 0.020
regulation of cell differentiation GO:0045595 142 0.020
multicellular organism growth GO:0035264 4 0.020
neuroblast fate commitment GO:0014017 1 0.020
regulation of signaling GO:0023051 235 0.020
protein modification by small protein conjugation or removal GO:0070647 14 0.019
negative regulation of cell differentiation GO:0045596 46 0.019
cellular protein modification process GO:0006464 100 0.019
mitotic cell cycle embryonic GO:0045448 2 0.019
mitotic dna damage checkpoint GO:0044773 4 0.019
chromatin modification GO:0016568 21 0.019
protein complex biogenesis GO:0070271 30 0.019
macromolecule biosynthetic process GO:0009059 227 0.019
Human Mouse Worm Fly
regulation of rna metabolic process GO:0051252 224 0.019
negative regulation of apoptotic process GO:0043066 55 0.018
skeletal system morphogenesis GO:0048705 102 0.018
cell death GO:0008219 121 0.018
cellular macromolecule catabolic process GO:0044265 12 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
positive regulation of macromolecule metabolic process GO:0010604 93 0.018
protein maturation GO:0051604 12 0.018
negative regulation of cell cycle phase transition GO:1901988 5 0.018
positive regulation of chromosome organization GO:2001252 1 0.018
phagocytosis GO:0006909 3 0.018
negative regulation of protein processing GO:0010955 10 0.018
regulation of response to stimulus GO:0048583 269 0.018
cell projection morphogenesis GO:0048858 244 0.017
nucleobase containing compound metabolic process GO:0006139 274 0.017
Human Mouse Worm Fly
mrna metabolic process GO:0016071 20 0.017
response to other organism GO:0051707 97 0.017
Fly
regulation of protein targeting GO:1903533 2 0.016
cell cycle g2 m phase transition GO:0044839 4 0.016
dna metabolic process GO:0006259 27 0.016
Human Mouse Worm Fly
cellular protein metabolic process GO:0044267 129 0.016
negative regulation of signal transduction GO:0009968 94 0.016
regulation of biological quality GO:0065008 263 0.016
establishment of rna localization GO:0051236 3 0.016
protein acetylation GO:0006473 2 0.016
b cell activation GO:0042113 2 0.016
protein complex subunit organization GO:0071822 46 0.016
cell cycle phase transition GO:0044770 9 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
non recombinational repair GO:0000726 2 0.015
negative regulation of protein transport GO:0051224 3 0.015
small molecule metabolic process GO:0044281 77 0.015
protein ubiquitination GO:0016567 11 0.015
neuroblast fate determination GO:0007400 1 0.015
regulation of signal transduction GO:0009966 225 0.015
programmed cell death GO:0012501 119 0.015
regulation of synapse organization GO:0050807 3 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.015
intra s dna damage checkpoint GO:0031573 1 0.015
aging GO:0007568 2 0.015
Worm
negative regulation of developmental process GO:0051093 65 0.015
regulation of protein processing GO:0070613 10 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
pyrimidine containing compound biosynthetic process GO:0072528 2 0.015
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.014
cellular component movement GO:0006928 335 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
negative regulation of metabolic process GO:0009892 86 0.014
negative regulation of protein maturation GO:1903318 10 0.014
negative regulation of cell communication GO:0010648 96 0.014
single organism localization GO:1902578 225 0.014
regulation of production of molecular mediator of immune response GO:0002700 1 0.014
single organism transport GO:0044765 206 0.014
oxoacid metabolic process GO:0043436 31 0.014
mitotic cell cycle phase transition GO:0044772 9 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
locomotion GO:0040011 313 0.014
Worm
negative regulation of rna biosynthetic process GO:1902679 45 0.013
cilium morphogenesis GO:0060271 85 0.013
cilium assembly GO:0042384 58 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
negative regulation of programmed cell death GO:0043069 58 0.013
double strand break repair GO:0006302 3 0.013
mitotic cell cycle checkpoint GO:0007093 5 0.013
response to yeast GO:0001878 23 0.013
cellular localization GO:0051641 97 0.013
nitrogen compound transport GO:0071705 23 0.013
cell morphogenesis GO:0000902 289 0.013
regulation of cell death GO:0010941 103 0.013
regulation of cardiac muscle tissue development GO:0055024 1 0.013
protein polymerization GO:0051258 4 0.013
cellular response to hypoxia GO:0071456 1 0.013
cell part morphogenesis GO:0032990 246 0.013
immunoglobulin production GO:0002377 1 0.013
liver development GO:0001889 96 0.013
protein import GO:0017038 3 0.013
protein localization GO:0008104 40 0.012
cellular response to decreased oxygen levels GO:0036294 1 0.012
protein import into nucleus GO:0006606 3 0.012
negative regulation of cell death GO:0060548 60 0.012
protein modification by small protein conjugation GO:0032446 13 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
Human Mouse
organic substance transport GO:0071702 58 0.012
centrosome organization GO:0051297 1 0.012
Fly
regulation of organelle organization GO:0033043 29 0.012
negative regulation of cell cycle g2 m phase transition GO:1902750 1 0.012
microtubule cytoskeleton organization GO:0000226 33 0.012
Fly
negative regulation of protein phosphorylation GO:0001933 4 0.012
cellular amine metabolic process GO:0044106 2 0.012
muscle cell development GO:0055001 115 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
regulation of cell proliferation GO:0042127 37 0.011
positive regulation of catabolic process GO:0009896 4 0.011
regulation of cell cycle process GO:0010564 20 0.011
Mouse
anterior posterior pattern specification GO:0009952 152 0.011
cellular response to external stimulus GO:0071496 2 0.011
protein localization to microtubule cytoskeleton GO:0072698 1 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.011
fertilization GO:0009566 3 0.011
mitochondrion organization GO:0007005 4 0.011
eye development GO:0001654 277 0.011
immune effector process GO:0002252 23 0.011
cellular response to dna damage stimulus GO:0006974 24 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
dna replication GO:0006260 6 0.011
Human Mouse Worm Fly
regulation of cellular amine metabolic process GO:0033238 0 0.010
mrna transport GO:0051028 2 0.010
skeletal system development GO:0001501 181 0.010
cell cycle arrest GO:0007050 1 0.010
centrosome cycle GO:0007098 1 0.010
Fly
cellular aldehyde metabolic process GO:0006081 4 0.010
cell proliferation GO:0008283 80 0.010
nucleic acid transport GO:0050657 2 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
phosphorylation GO:0016310 69 0.010

cdt1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
disease of cellular proliferation DOID:14566 0 0.011