Danio rerio

61 known processes

cdx4

caudal type homeo box transcription factor 4

(Aliases: cad1,kugelig,cdx1,id:ibd5107,cb546,CHUNP6923,MGC91785,id:ibd2812,kgg,id:ibd1215,MGC174157)

cdx4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 274 0.990
mesenchyme development GO:0060485 127 0.964
hemopoiesis GO:0030097 183 0.940
digestive system development GO:0055123 289 0.936
regulation of nitrogen compound metabolic process GO:0051171 251 0.932
Human Zebrafish Mouse Fly
epithelial tube morphogenesis GO:0060562 148 0.929
vasculature development GO:0001944 278 0.921
Mouse
appendage morphogenesis GO:0035107 56 0.918
segmentation GO:0035282 97 0.897
organic cyclic compound biosynthetic process GO:1901362 223 0.896
Human Zebrafish Mouse Fly
anterior posterior pattern specification GO:0009952 152 0.890
cell fate commitment GO:0045165 99 0.888
brain development GO:0007420 293 0.876
regulation of gene expression GO:0010468 265 0.871
Human Zebrafish Mouse Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.867
Human Zebrafish Mouse Fly
nucleic acid templated transcription GO:0097659 181 0.863
Human Zebrafish Mouse Fly
digestive tract morphogenesis GO:0048546 231 0.861
rna biosynthetic process GO:0032774 181 0.855
Human Zebrafish Mouse Fly
fin development GO:0033333 77 0.853
blood vessel development GO:0001568 246 0.849
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.844
Human Zebrafish Mouse Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.836
Human Mouse Fly
cell motility GO:0048870 244 0.832
blood vessel morphogenesis GO:0048514 216 0.829
ventral spinal cord development GO:0021517 35 0.820
regulation of macromolecule metabolic process GO:0060255 317 0.818
Human Zebrafish Mouse Fly
regulation of metabolic process GO:0019222 359 0.816
Human Zebrafish Mouse Fly
pectoral fin development GO:0033339 50 0.813
appendage development GO:0048736 80 0.811
regulation of multicellular organismal process GO:0051239 277 0.805
macromolecule biosynthetic process GO:0009059 227 0.804
Human Zebrafish Mouse Fly
somite development GO:0061053 96 0.804
sensory organ development GO:0007423 393 0.798
heart morphogenesis GO:0003007 156 0.797
skeletal system development GO:0001501 181 0.782
cellular macromolecule biosynthetic process GO:0034645 224 0.765
Human Zebrafish Mouse Fly
immune system development GO:0002520 191 0.761
response to chemical GO:0042221 320 0.754
central nervous system development GO:0007417 387 0.752
nucleic acid metabolic process GO:0090304 244 0.744
Human Zebrafish Mouse Fly
dorsal ventral pattern formation GO:0009953 125 0.730
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.725
diencephalon development GO:0021536 58 0.718
axial mesoderm formation GO:0048320 4 0.714
hepaticobiliary system development GO:0061008 98 0.703
Zebrafish
neural tube development GO:0021915 62 0.703
cellular component morphogenesis GO:0032989 336 0.696
regulation of biosynthetic process GO:0009889 250 0.687
Human Zebrafish Mouse Fly
regulation of immune system process GO:0002682 34 0.684
Fly
positive regulation of rna metabolic process GO:0051254 59 0.680
Human Zebrafish Fly
negative regulation of biological process GO:0048519 304 0.678
Mouse
regulation of cellular metabolic process GO:0031323 320 0.674
Human Zebrafish Mouse Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.672
cell morphogenesis GO:0000902 289 0.671
somitogenesis GO:0001756 87 0.658
regulation of response to stimulus GO:0048583 269 0.656
Fly
liver development GO:0001889 96 0.656
Zebrafish
positive regulation of cellular biosynthetic process GO:0031328 68 0.653
Human Zebrafish Fly
chordate embryonic development GO:0043009 271 0.643
localization of cell GO:0051674 244 0.638
regulation of transcription dna templated GO:0006355 213 0.638
Human Zebrafish Mouse Fly
mesenchymal cell differentiation GO:0048762 87 0.634
determination of bilateral symmetry GO:0009855 204 0.626
regulation of macromolecule biosynthetic process GO:0010556 225 0.619
Human Zebrafish Mouse Fly
atrioventricular valve formation GO:0003190 3 0.598
positive regulation of biological process GO:0048518 253 0.595
Human Zebrafish Fly
sensory organ morphogenesis GO:0090596 200 0.595
response to organic substance GO:0010033 153 0.595
cell fate specification GO:0001708 68 0.575
embryo development ending in birth or egg hatching GO:0009792 271 0.575
cellular nitrogen compound metabolic process GO:0034641 290 0.570
Human Zebrafish Mouse Fly
immune system process GO:0002376 241 0.566
pancreas development GO:0031016 84 0.552
homeostatic process GO:0042592 142 0.550
morphogenesis of an epithelium GO:0002009 333 0.538
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.532
Human Zebrafish Mouse Fly
locomotion GO:0040011 313 0.524
common bile duct development GO:0061009 13 0.522
heart valve formation GO:0003188 4 0.520
mesenchymal cell development GO:0014031 78 0.518
embryonic organ development GO:0048568 381 0.516
Mouse
neural crest cell development GO:0014032 62 0.511
neuron fate specification GO:0048665 20 0.510
positive regulation of epithelial cell proliferation GO:0050679 1 0.505
ectodermal placode formation GO:0060788 26 0.498
nucleobase containing compound biosynthetic process GO:0034654 205 0.494
Human Zebrafish Mouse Fly
transcription dna templated GO:0006351 181 0.489
Human Zebrafish Mouse Fly
cell surface receptor signaling pathway GO:0007166 325 0.488
specification of symmetry GO:0009799 204 0.484
ventral spinal cord interneuron differentiation GO:0021514 12 0.482
heart development GO:0007507 313 0.476
signal transduction GO:0007165 455 0.476
notochord development GO:0030903 54 0.472
otic vesicle development GO:0071599 42 0.469
floor plate morphogenesis GO:0033505 12 0.468
rhombomere 5 morphogenesis GO:0021664 1 0.464
cell differentiation in spinal cord GO:0021515 40 0.461
hindbrain development GO:0030902 91 0.457
heart looping GO:0001947 94 0.457
regulation of cell communication GO:0010646 232 0.455
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.452
Human Zebrafish Mouse Fly
leukocyte differentiation GO:0002521 25 0.452
regulation of rna metabolic process GO:0051252 224 0.447
Human Zebrafish Mouse Fly
neural crest cell differentiation GO:0014033 72 0.436
regulation of neuron differentiation GO:0045664 56 0.435
regulation of biological quality GO:0065008 263 0.428
negative regulation of cellular process GO:0048523 283 0.424
Mouse
foregut morphogenesis GO:0007440 4 0.421
fin morphogenesis GO:0033334 53 0.420
ectodermal placode morphogenesis GO:0071697 32 0.415
lymphocyte differentiation GO:0030098 9 0.412
neuromast development GO:0048884 46 0.407
positive regulation of gene expression GO:0010628 71 0.407
Human Zebrafish Fly
regulation of rna biosynthetic process GO:2001141 213 0.402
Human Zebrafish Mouse Fly
gliogenesis GO:0042063 45 0.402
astrocyte differentiation GO:0048708 1 0.401
myeloid cell differentiation GO:0030099 86 0.400
cartilage development GO:0051216 96 0.398
gene expression GO:0010467 252 0.397
Human Zebrafish Mouse Fly
mesodermal cell differentiation GO:0048333 21 0.396
endoderm development GO:0007492 49 0.389
Zebrafish
otic vesicle formation GO:0030916 27 0.388
regulation of signal transduction GO:0009966 225 0.381
positive regulation of cellular process GO:0048522 201 0.380
Human Zebrafish Fly
forebrain development GO:0030900 96 0.374
chemotaxis GO:0006935 104 0.368
tube morphogenesis GO:0035239 349 0.359
cellular ketone metabolic process GO:0042180 11 0.357
eye development GO:0001654 277 0.354
heterocycle metabolic process GO:0046483 290 0.354
Human Zebrafish Mouse Fly
renal system development GO:0072001 94 0.354
leukocyte activation GO:0045321 12 0.353
eye morphogenesis GO:0048592 144 0.352
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.350
organelle organization GO:0006996 227 0.350
determination of heart left right asymmetry GO:0061371 117 0.349
lateral line system development GO:0048925 76 0.348
regeneration GO:0031099 91 0.345
ameboidal type cell migration GO:0001667 143 0.342
regulation of endodermal cell fate specification GO:0042663 15 0.338
head development GO:0060322 303 0.333
compound eye development GO:0048749 2 0.328
oligodendrocyte differentiation GO:0048709 23 0.327
determination of left right symmetry GO:0007368 179 0.322
sensory system development GO:0048880 76 0.321
regulation of multicellular organismal development GO:2000026 223 0.317
cell projection morphogenesis GO:0048858 244 0.316
heterocycle biosynthetic process GO:0018130 215 0.313
Human Zebrafish Mouse Fly
mesoderm morphogenesis GO:0048332 51 0.311
central nervous system myelin formation GO:0032289 1 0.310
embryonic pectoral fin morphogenesis GO:0035118 24 0.307
single organism reproductive process GO:0044702 40 0.306
Mouse
cell migration GO:0016477 237 0.305
nitrogen compound metabolic process GO:0006807 319 0.303
Human Zebrafish Mouse Fly
somite specification GO:0001757 12 0.302
floor plate formation GO:0021508 12 0.302
endodermal cell fate specification GO:0001714 17 0.299
mesoderm formation GO:0001707 43 0.298
positive regulation of signaling GO:0023056 56 0.296
spinal cord motor neuron differentiation GO:0021522 26 0.295
aging GO:0007568 2 0.294
embryonic skeletal system morphogenesis GO:0048704 93 0.289
chemical homeostasis GO:0048878 49 0.286
telencephalon development GO:0021537 14 0.286
stem cell differentiation GO:0048863 117 0.284
cellular response to organic substance GO:0071310 105 0.283
regulation of developmental process GO:0050793 247 0.283
cellular aromatic compound metabolic process GO:0006725 295 0.283
Human Zebrafish Mouse Fly
ear morphogenesis GO:0042471 64 0.281
rostrocaudal neural tube patterning GO:0021903 29 0.275
rna metabolic process GO:0016070 219 0.275
Human Zebrafish Mouse Fly
digestive tract development GO:0048565 265 0.270
gall bladder development GO:0061010 1 0.269
otic placode formation GO:0043049 23 0.264
arterial endothelial cell differentiation GO:0060842 2 0.259
stem cell development GO:0048864 82 0.257
embryonic organ morphogenesis GO:0048562 274 0.255
cellular biosynthetic process GO:0044249 286 0.252
Human Zebrafish Mouse Fly
circulatory system process GO:0003013 87 0.252
positive regulation of cell activation GO:0050867 1 0.251
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.251
spinal cord motor neuron cell fate specification GO:0021520 8 0.251
rhombomere morphogenesis GO:0021593 17 0.248
regulation of cellular amino acid metabolic process GO:0006521 0 0.247
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.246
neural crest cell migration GO:0001755 42 0.241
leukocyte proliferation GO:0070661 1 0.237
axonogenesis GO:0007409 152 0.235
cellular response to endogenous stimulus GO:0071495 68 0.234
cell part morphogenesis GO:0032990 246 0.234
amine metabolic process GO:0009308 2 0.233
neuron fate commitment GO:0048663 26 0.232
mesodermal cell fate commitment GO:0001710 14 0.231
neuron projection guidance GO:0097485 86 0.228
inner ear morphogenesis GO:0042472 63 0.228
heart formation GO:0060914 13 0.225
axon development GO:0061564 166 0.224
otic vesicle morphogenesis GO:0071600 34 0.221
stem cell fate commitment GO:0048865 1 0.221
endocardium formation GO:0060214 1 0.220
retinoic acid receptor signaling pathway GO:0048384 16 0.218
negative regulation of biosynthetic process GO:0009890 55 0.214
Mouse
developmental process involved in reproduction GO:0003006 27 0.214
Mouse
anatomical structure arrangement GO:0048532 2 0.213
regulation of nucleic acid templated transcription GO:1903506 213 0.212
Human Zebrafish Mouse Fly
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.211
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.210
neuron development GO:0048666 262 0.208
cell migration involved in heart development GO:0060973 22 0.206
regulation of membrane potential GO:0042391 23 0.202
growth GO:0040007 174 0.200
mononuclear cell proliferation GO:0032943 1 0.200
aorta development GO:0035904 4 0.199
ectodermal placode development GO:0071696 37 0.198
axis elongation involved in somitogenesis GO:0090245 2 0.196
notochord cell differentiation GO:0060034 18 0.194
negative regulation of cell differentiation GO:0045596 46 0.192
regulation of cellular biosynthetic process GO:0031326 245 0.191
Human Zebrafish Mouse Fly
ventral spinal cord interneuron specification GO:0021521 3 0.190
negative regulation of gene expression GO:0010629 65 0.189
Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.187
embryonic appendage morphogenesis GO:0035113 30 0.187
aromatic compound biosynthetic process GO:0019438 217 0.186
Human Zebrafish Mouse Fly
pericardium morphogenesis GO:0003344 1 0.183
cellular amine metabolic process GO:0044106 2 0.182
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.181
Human Zebrafish Fly
negative regulation of rna metabolic process GO:0051253 48 0.181
Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.180
Human Mouse Fly
heart jogging GO:0003146 40 0.179
pectoral fin morphogenesis GO:0035138 29 0.178
urogenital system development GO:0001655 97 0.177
mesodermal cell fate specification GO:0007501 12 0.177
endocardial cell differentiation GO:0060956 5 0.177
larval development GO:0002164 2 0.175
rhombomere 4 development GO:0021570 5 0.173
regulation of signaling GO:0023051 235 0.172
lipid storage GO:0019915 1 0.172
forebrain dorsal ventral pattern formation GO:0021798 1 0.170
spinal cord development GO:0021510 46 0.167
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.164
Human Zebrafish Fly
segment polarity determination GO:0007367 1 0.163
erythrocyte differentiation GO:0030218 54 0.163
neural tube patterning GO:0021532 33 0.163
regulation of cellular amine metabolic process GO:0033238 0 0.161
lymphocyte activation GO:0046649 10 0.160
maintenance of location GO:0051235 4 0.160
cell projection organization GO:0030030 284 0.160
notochord morphogenesis GO:0048570 17 0.159
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.157
axial mesoderm morphogenesis GO:0048319 8 0.156
atrial ventricular junction remodeling GO:0003294 2 0.156
endodermal cell fate determination GO:0007493 2 0.156
fin regeneration GO:0031101 51 0.154
enzyme linked receptor protein signaling pathway GO:0007167 106 0.154
oxoacid metabolic process GO:0043436 31 0.154
muscle structure development GO:0061061 196 0.153
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.153
cell proliferation GO:0008283 80 0.153
Zebrafish Fly
formation of primary germ layer GO:0001704 62 0.153
Zebrafish
positive regulation of notch signaling pathway GO:0045747 3 0.152
melanocyte differentiation GO:0030318 26 0.151
negative regulation of cell death GO:0060548 60 0.150
endoderm formation GO:0001706 29 0.149
Zebrafish
floor plate development GO:0033504 15 0.149
regulation of anatomical structure morphogenesis GO:0022603 130 0.149
positive regulation of transcription dna templated GO:0045893 57 0.149
Human Zebrafish Fly
neuroblast proliferation GO:0007405 2 0.148
organic substance biosynthetic process GO:1901576 289 0.147
Human Zebrafish Mouse Fly
periodic partitioning GO:0007365 1 0.147
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.147
regulation of mesodermal cell fate specification GO:0042661 9 0.146
kidney development GO:0001822 92 0.146
aorta morphogenesis GO:0035909 3 0.145
regulation of leukocyte differentiation GO:1902105 5 0.145
regulation of epithelial cell proliferation GO:0050678 3 0.144
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.144
connective tissue development GO:0061448 99 0.144
positive regulation of biosynthetic process GO:0009891 68 0.142
Human Zebrafish Fly
response to other organism GO:0051707 97 0.141
Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.141
Human Zebrafish Fly
response to stress GO:0006950 263 0.139
nucleobase containing compound metabolic process GO:0006139 274 0.139
Human Zebrafish Mouse Fly
taxis GO:0042330 109 0.139
regulation of apoptotic process GO:0042981 98 0.138
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.138
organic cyclic compound metabolic process GO:1901360 301 0.137
Human Zebrafish Mouse Fly
hypochord development GO:0055016 3 0.137
central nervous system neuron differentiation GO:0021953 74 0.136
bmp signaling pathway GO:0030509 52 0.135
gland development GO:0048732 143 0.134
Zebrafish
determination of left right asymmetry in diencephalon GO:0035462 4 0.134
morphogenesis of an epithelial fold GO:0060571 1 0.133
homeostasis of number of cells GO:0048872 62 0.132
striated muscle cell differentiation GO:0051146 129 0.132
regulation of canonical wnt signaling pathway GO:0060828 34 0.130
regulation of bmp signaling pathway GO:0030510 39 0.129
epidermal cell fate specification GO:0009957 4 0.128
regulation of gastrulation GO:0010470 24 0.127
embryonic heart tube morphogenesis GO:0003143 108 0.125
negative regulation of mesodermal cell fate specification GO:0042662 3 0.125
heart field specification GO:0003128 1 0.124
nephron epithelium morphogenesis GO:0072088 1 0.124
outflow tract morphogenesis GO:0003151 1 0.124
negative regulation of rna biosynthetic process GO:1902679 45 0.123
Mouse
vasculogenesis GO:0001570 41 0.123
regulation of embryonic development GO:0045995 47 0.122
embryonic digestive tract development GO:0048566 4 0.122
cardiogenic plate morphogenesis GO:0003142 1 0.121
epithelial cell differentiation GO:0030855 116 0.121
Zebrafish
determination of liver left right asymmetry GO:0071910 11 0.121
cardiac endothelial cell differentiation GO:0003348 5 0.120
endocardium development GO:0003157 9 0.120
negative regulation of nodal signaling pathway GO:1900108 4 0.120
cardiocyte differentiation GO:0035051 44 0.120
limbic system development GO:0021761 16 0.119
cellular response to lipopolysaccharide GO:0071222 3 0.119
metencephalon development GO:0022037 27 0.119
endodermal digestive tract morphogenesis GO:0061031 2 0.119
embryonic pattern specification GO:0009880 44 0.118
Fly
photoreceptor cell fate commitment GO:0046552 1 0.117
hematopoietic stem cell differentiation GO:0060218 20 0.115
generation of neurons GO:0048699 385 0.115
cellular component assembly involved in morphogenesis GO:0010927 107 0.115
hepatic duct development GO:0061011 2 0.114
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.114
Human Zebrafish Fly
determination of pancreatic left right asymmetry GO:0035469 11 0.114
positive regulation of metabolic process GO:0009893 108 0.113
Human Zebrafish Fly
neural plate pattern specification GO:0060896 12 0.113
primary neural tube formation GO:0014020 1 0.112
regulation of oligodendrocyte differentiation GO:0048713 1 0.112
regulation of primary metabolic process GO:0080090 311 0.112
Human Zebrafish Mouse Fly
mesoderm development GO:0007498 88 0.111
negative regulation of wnt signaling pathway involved in heart development GO:0003308 2 0.111
retinal rod cell development GO:0046548 4 0.110
axis specification GO:0009798 43 0.110
regulation of cellular ketone metabolic process GO:0010565 7 0.109
oligodendrocyte development GO:0014003 7 0.109
regulation of endodermal cell differentiation GO:1903224 15 0.109
dorsal aorta morphogenesis GO:0035912 3 0.109
regulation of cell activation GO:0050865 1 0.109
embryonic foregut morphogenesis GO:0048617 1 0.108
negative regulation of leukocyte differentiation GO:1902106 1 0.107
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.107
stem cell maintenance GO:0019827 4 0.106
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.105
proepicardium development GO:0003342 4 0.104
positive regulation of leukocyte differentiation GO:1902107 1 0.104
endocardium morphogenesis GO:0003160 4 0.104
endodermal cell differentiation GO:0035987 19 0.104
nerve development GO:0021675 45 0.104
motor neuron axon guidance GO:0008045 23 0.103
embryonic hemopoiesis GO:0035162 53 0.103
nephron epithelium development GO:0072009 16 0.102
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.102
Mouse
cellular amino acid metabolic process GO:0006520 7 0.101
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.101
positive regulation of cell communication GO:0010647 56 0.101
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.101
Mouse
negative regulation of signal transduction GO:0009968 94 0.101
cell proliferation involved in heart morphogenesis GO:0061323 2 0.101
retina development in camera type eye GO:0060041 146 0.100
response to external stimulus GO:0009605 264 0.099
Fly
ear development GO:0043583 127 0.099
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.098
dorsal ventral neural tube patterning GO:0021904 1 0.098
negative regulation of apoptotic process GO:0043066 55 0.098
pigment cell differentiation GO:0050931 38 0.098
positive regulation of stem cell proliferation GO:2000648 1 0.097
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.097
neuron projection morphogenesis GO:0048812 161 0.097
embryonic cranial skeleton morphogenesis GO:0048701 90 0.097
epithelial cell proliferation GO:0050673 17 0.095
Zebrafish
positive regulation of muscle organ development GO:0048636 1 0.094
inner ear development GO:0048839 126 0.094
determination of left right asymmetry in nervous system GO:0035545 4 0.094
specification of organ position GO:0010159 3 0.093
response to oxygen containing compound GO:1901700 55 0.093
regulation of stem cell proliferation GO:0072091 2 0.091
negative regulation of neurogenesis GO:0050768 20 0.091
positive regulation of map kinase activity GO:0043406 3 0.091
regulation of programmed cell death GO:0043067 101 0.091
determination of dorsal ventral asymmetry GO:0048262 34 0.091
endodermal cell fate commitment GO:0001711 18 0.090
endothelium development GO:0003158 25 0.089
epithelial cell development GO:0002064 42 0.089
multicellular organismal reproductive process GO:0048609 35 0.087
cellular response to biotic stimulus GO:0071216 3 0.086
muscle cell differentiation GO:0042692 139 0.086
tissue regeneration GO:0042246 74 0.086
blastoderm segmentation GO:0007350 6 0.085
Fly
spinal cord anterior posterior patterning GO:0021512 1 0.084
multi organism reproductive process GO:0044703 36 0.084
cellular response to retinoic acid GO:0071300 1 0.084
camera type eye development GO:0043010 222 0.084
negative regulation of cellular biosynthetic process GO:0031327 55 0.084
Mouse
axial mesoderm development GO:0048318 10 0.083
cellular response to chemical stimulus GO:0070887 157 0.082
cardioblast migration GO:0003260 7 0.082
tissue remodeling GO:0048771 4 0.082
regulation of hormone levels GO:0010817 21 0.081
myelination GO:0042552 18 0.081
negative regulation of transcription elongation from rna polymerase ii promoter GO:0034244 1 0.081
optic placode formation involved in camera type eye formation GO:0046619 3 0.080
pronephros development GO:0048793 69 0.080
cellular component movement GO:0006928 335 0.080
positive regulation of cell fate commitment GO:0010455 1 0.080
lymphocyte proliferation GO:0046651 1 0.079
organic substance transport GO:0071702 58 0.078
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.077
Human Fly
biosynthetic process GO:0009058 294 0.077
Human Zebrafish Mouse Fly
t cell differentiation GO:0030217 6 0.076
kupffer s vesicle development GO:0070121 50 0.076
dorsal ventral axis specification GO:0009950 14 0.076
ion transmembrane transport GO:0034220 91 0.075
carboxylic acid metabolic process GO:0019752 22 0.075
forebrain anterior posterior pattern specification GO:0021797 3 0.075
neuron migration GO:0001764 22 0.075
morphogenesis of a branching epithelium GO:0061138 16 0.075
positive regulation of cell cycle GO:0045787 3 0.074
t cell differentiation in thymus GO:0033077 6 0.074
forebrain regionalization GO:0021871 4 0.073
multicellular organism growth GO:0035264 4 0.073
organic acid metabolic process GO:0006082 31 0.073
epithalamus development GO:0021538 10 0.073
lateral line development GO:0048882 66 0.073
wound healing GO:0042060 90 0.072
negative regulation of myeloid cell differentiation GO:0045638 1 0.072
bmp signaling pathway involved in heart development GO:0061312 15 0.072
glial cell differentiation GO:0010001 42 0.072
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.072
Mouse
determination of dorsal identity GO:0048263 13 0.071
negative regulation of immune system process GO:0002683 7 0.071
negative regulation of nervous system development GO:0051961 22 0.071
oligodendrocyte cell fate specification GO:0021778 4 0.071
intrahepatic bile duct development GO:0035622 11 0.070
cartilage development involved in endochondral bone morphogenesis GO:0060351 8 0.069
negative regulation of bmp signaling pathway GO:0030514 13 0.069
fourth ventricle development GO:0021592 8 0.068
cell fate specification involved in pattern specification GO:0060573 3 0.068
embryonic digestive tract morphogenesis GO:0048557 3 0.068
lateral mesoderm development GO:0048368 23 0.068
negative regulation of response to stimulus GO:0048585 104 0.068
multi organism process GO:0051704 134 0.067
Fly
regulation of cell differentiation GO:0045595 142 0.067
axial mesodermal cell fate specification GO:0048327 3 0.067
positive regulation of rna biosynthetic process GO:1902680 57 0.066
Human Zebrafish Fly
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.066
neural plate anterior posterior regionalization GO:0021999 8 0.065
odontogenesis of dentin containing tooth GO:0042475 1 0.065
regulation of nervous system development GO:0051960 90 0.065
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.065
negative regulation of gliogenesis GO:0014014 1 0.065
bmp signaling pathway involved in heart jogging GO:0003303 14 0.064
negative regulation of cell development GO:0010721 26 0.064
developmental growth GO:0048589 166 0.064
midbrain hindbrain boundary development GO:0030917 23 0.064
regulation of stem cell differentiation GO:2000736 4 0.064
death GO:0016265 121 0.062
positive regulation of macromolecule metabolic process GO:0010604 93 0.062
Human Zebrafish Fly
response to endogenous stimulus GO:0009719 83 0.062
retinal ganglion cell axon guidance GO:0031290 35 0.062
skeletal muscle tissue development GO:0007519 67 0.061
small molecule metabolic process GO:0044281 77 0.061
neuron differentiation GO:0030182 353 0.061
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.061
meiotic nuclear division GO:0007126 4 0.061
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.060
cranial nerve development GO:0021545 42 0.060
ventral spinal cord interneuron fate commitment GO:0060579 3 0.060
nephron tubule morphogenesis GO:0072078 1 0.060
epithelial to mesenchymal transition GO:0001837 21 0.059
g1 s transition of mitotic cell cycle GO:0000082 1 0.059
neuron projection development GO:0031175 180 0.059
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.058
angiogenesis GO:0001525 158 0.058
anterior posterior axis specification GO:0009948 20 0.057
eye photoreceptor cell development GO:0042462 30 0.057
regulation of multicellular organism growth GO:0040014 4 0.057
glial cell migration GO:0008347 3 0.057
hindbrain morphogenesis GO:0021575 22 0.057
renal tubule morphogenesis GO:0061333 1 0.057
rhombomere 5 development GO:0021571 4 0.057
blood circulation GO:0008015 87 0.057
cell cell signaling GO:0007267 52 0.057
regulation of inner ear receptor cell differentiation GO:2000980 1 0.056
axial mesoderm structural organization GO:0048331 2 0.055
alcohol biosynthetic process GO:0046165 2 0.055
rhombomere development GO:0021546 19 0.054
abducens nucleus development GO:0021742 2 0.054
gastrulation with mouth forming second GO:0001702 44 0.053
gastrulation GO:0007369 208 0.053
Zebrafish Fly
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.053
chemosensory behavior GO:0007635 1 0.053
cell death GO:0008219 121 0.052
behavior GO:0007610 74 0.052
developmental maturation GO:0021700 34 0.052

cdx4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.114
maturity onset diabetes of the young DOID:0050524 0 0.078