Danio rerio

68 known processes

chm

choroideremia

(Aliases: REP1)

chm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.486
establishment of localization GO:0051234 244 0.331
eye development GO:0001654 277 0.278
pronuclear migration GO:0035046 1 0.215
regulation of biological quality GO:0065008 263 0.189
organelle organization GO:0006996 227 0.187
single organism transport GO:0044765 206 0.168
nuclear migration GO:0007097 3 0.167
retina development in camera type eye GO:0060041 146 0.161
embryo development ending in birth or egg hatching GO:0009792 271 0.155
cellular response to external stimulus GO:0071496 2 0.135
cell surface receptor signaling pathway GO:0007166 325 0.125
regulation of cell communication GO:0010646 232 0.116
regulation of multicellular organismal development GO:2000026 223 0.110
single organism localization GO:1902578 225 0.110
signal transduction GO:0007165 455 0.105
brain development GO:0007420 293 0.104
pigmentation GO:0043473 85 0.101
transport GO:0006810 220 0.101
fertilization GO:0009566 3 0.095
sensory organ development GO:0007423 393 0.092
generation of neurons GO:0048699 385 0.089
regulation of response to stimulus GO:0048583 269 0.084
cellular component maintenance GO:0043954 3 0.079
central nervous system development GO:0007417 387 0.076
pigment granule localization GO:0051875 25 0.074
camera type eye development GO:0043010 222 0.074
single fertilization GO:0007338 3 0.072
aging GO:0007568 2 0.068
regulation of anatomical structure morphogenesis GO:0022603 130 0.068
regulation of multicellular organismal process GO:0051239 277 0.065
cell part morphogenesis GO:0032990 246 0.065
positive regulation of transport GO:0051050 2 0.063
nonmotile primary cilium assembly GO:0035058 2 0.062
cellular response to nutrient levels GO:0031669 2 0.057
protein localization to plasma membrane GO:0072659 1 0.055
reproduction GO:0000003 40 0.055
autophagy GO:0006914 4 0.054
regulation of dendrite development GO:0050773 3 0.054
regulation of developmental process GO:0050793 247 0.054
sensory organ morphogenesis GO:0090596 200 0.052
regulation of signaling GO:0023051 235 0.051
cellular response to extracellular stimulus GO:0031668 2 0.051
establishment of organelle localization GO:0051656 45 0.050
medulla oblongata development GO:0021550 4 0.050
regulation of establishment of protein localization GO:0070201 4 0.049
regulation of glucose transport GO:0010827 1 0.049
heart development GO:0007507 313 0.048
neuron development GO:0048666 262 0.047
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.046
cellular macromolecule metabolic process GO:0044260 391 0.046
regulation of neurogenesis GO:0050767 87 0.045
regulation of ion transmembrane transporter activity GO:0032412 2 0.045
biosynthetic process GO:0009058 294 0.045
nucleoside monophosphate catabolic process GO:0009125 4 0.045
cellular biosynthetic process GO:0044249 286 0.044
establishment of protein localization to plasma membrane GO:0090002 1 0.044
gene expression GO:0010467 252 0.043
specification of symmetry GO:0009799 204 0.043
maintenance of epithelial cell apical basal polarity GO:0045199 5 0.041
head development GO:0060322 303 0.041
cellular localization GO:0051641 97 0.040
adherens junction maintenance GO:0034334 2 0.040
system process GO:0003008 185 0.040
regulation of glucose import GO:0046324 1 0.040
microtubule based movement GO:0007018 33 0.040
regulation of macromolecule metabolic process GO:0060255 317 0.039
neuron differentiation GO:0030182 353 0.039
positive regulation of secretion by cell GO:1903532 1 0.039
cellular component morphogenesis GO:0032989 336 0.038
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.037
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.037
response to stress GO:0006950 263 0.037
death GO:0016265 121 0.036
epithelial tube morphogenesis GO:0060562 148 0.036
cellular component movement GO:0006928 335 0.036
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.035
apoptotic process GO:0006915 116 0.035
regulation of nervous system development GO:0051960 90 0.034
embryonic organ development GO:0048568 381 0.034
single organism organelle organization GO:1902589 199 0.034
atp catabolic process GO:0006200 4 0.034
transmembrane transport GO:0055085 120 0.034
primary neural tube formation GO:0014020 1 0.034
organic acid metabolic process GO:0006082 31 0.034
ribonucleoside monophosphate catabolic process GO:0009158 4 0.033
response to external stimulus GO:0009605 264 0.033
macromolecule biosynthetic process GO:0009059 227 0.033
negative regulation of autophagy GO:0010507 1 0.033
protein metabolic process GO:0019538 183 0.032
regulation of autophagy GO:0010506 3 0.032
extrinsic apoptotic signaling pathway GO:0097191 3 0.032
carboxylic acid metabolic process GO:0019752 22 0.032
adult behavior GO:0030534 2 0.032
establishment or maintenance of cell polarity GO:0007163 29 0.032
determination of left right symmetry GO:0007368 179 0.031
organonitrogen compound metabolic process GO:1901564 74 0.031
regulation of cellular component organization GO:0051128 86 0.031
glycerophospholipid biosynthetic process GO:0046474 1 0.031
morphogenesis of an epithelium GO:0002009 333 0.031
organic substance biosynthetic process GO:1901576 289 0.031
embryonic heart tube development GO:0035050 133 0.030
organic substance transport GO:0071702 58 0.029
organelle localization GO:0051640 49 0.029
regulation of neurotransmitter transport GO:0051588 1 0.029
oxoacid metabolic process GO:0043436 31 0.029
programmed cell death GO:0012501 119 0.029
positive regulation of biological process GO:0048518 253 0.029
regulation of metal ion transport GO:0010959 4 0.029
multi organism process GO:0051704 134 0.028
multicellular organismal reproductive process GO:0048609 35 0.028
cell cell junction maintenance GO:0045217 1 0.028
protein import into nucleus GO:0006606 3 0.028
establishment of synaptic vesicle localization GO:0097480 1 0.027
regulation of cell development GO:0060284 100 0.027
membrane fusion GO:0061025 2 0.027
amine metabolic process GO:0009308 2 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
regulation of cytokine production GO:0001817 3 0.026
cytoplasm organization GO:0007028 4 0.026
cell morphogenesis involved in differentiation GO:0000904 195 0.026
cellular amine metabolic process GO:0044106 2 0.026
retina morphogenesis in camera type eye GO:0060042 79 0.026
positive regulation of catabolic process GO:0009896 4 0.026
tube morphogenesis GO:0035239 349 0.026
establishment of melanosome localization GO:0032401 19 0.026
pyruvate metabolic process GO:0006090 1 0.025
regulation of reproductive process GO:2000241 4 0.025
maintenance of cell polarity GO:0030011 5 0.025
neuron projection development GO:0031175 180 0.025
cellular pigmentation GO:0033059 30 0.025
determination of bilateral symmetry GO:0009855 204 0.025
cellular amino acid metabolic process GO:0006520 7 0.025
regulation of cell differentiation GO:0045595 142 0.024
regulation of intracellular protein transport GO:0033157 3 0.024
digestive tract mesoderm development GO:0007502 1 0.024
positive regulation of secretion GO:0051047 1 0.024
microtubule based process GO:0007017 60 0.024
phagocytosis GO:0006909 3 0.024
cellular response to starvation GO:0009267 1 0.023
homeostatic process GO:0042592 142 0.023
positive regulation of glucose transport GO:0010828 1 0.023
exocytosis GO:0006887 1 0.023
locomotion GO:0040011 313 0.023
intracellular transport GO:0046907 32 0.023
regulation of epithelial cell proliferation GO:0050678 3 0.023
cell death GO:0008219 121 0.023
regulation of cell substrate adhesion GO:0010810 1 0.023
centrosome organization GO:0051297 1 0.023
negative regulation of catabolic process GO:0009895 3 0.023
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.022
cell junction maintenance GO:0034331 2 0.022
purine nucleoside monophosphate catabolic process GO:0009128 4 0.022
regulation of protein transport GO:0051223 3 0.022
nitrogen compound metabolic process GO:0006807 319 0.022
single organism metabolic process GO:0044710 217 0.022
regulation of intracellular signal transduction GO:1902531 57 0.022
cellular aromatic compound metabolic process GO:0006725 295 0.021
protein acylation GO:0043543 3 0.021
cell migration GO:0016477 237 0.021
endosomal transport GO:0016197 2 0.021
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 11 0.021
nucleus localization GO:0051647 8 0.021
golgi vesicle transport GO:0048193 3 0.021
reproductive process GO:0022414 40 0.021
regulation of transporter activity GO:0032409 2 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.021
cellular carbohydrate metabolic process GO:0044262 4 0.020
cytoskeleton organization GO:0007010 96 0.020
protein targeting to nucleus GO:0044744 3 0.020
negative regulation of response to stimulus GO:0048585 104 0.020
cellular macromolecule biosynthetic process GO:0034645 224 0.020
regulation of ion transport GO:0043269 22 0.020
regulation of gene expression GO:0010468 265 0.020
response to nutrient GO:0007584 3 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.020
dicarboxylic acid transport GO:0006835 1 0.020
microtubule based transport GO:0010970 10 0.020
regulation of binding GO:0051098 3 0.019
regulation of dendrite morphogenesis GO:0048814 3 0.019
cation transport GO:0006812 81 0.019
organelle fusion GO:0048284 3 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.019
regulation of multicellular organism growth GO:0040014 4 0.019
cytoskeleton dependent intracellular transport GO:0030705 10 0.019
regulation of metabolic process GO:0019222 359 0.019
single organism cellular localization GO:1902580 46 0.018
glycerolipid biosynthetic process GO:0045017 1 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.018
regulation of synapse organization GO:0050807 3 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
cell morphogenesis GO:0000902 289 0.018
oocyte anterior posterior axis specification GO:0007314 4 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
regulation of primary metabolic process GO:0080090 311 0.018
regulation of cell projection organization GO:0031344 44 0.018
phosphatidylinositol biosynthetic process GO:0006661 1 0.018
cell projection morphogenesis GO:0048858 244 0.018
cell projection organization GO:0030030 284 0.018
nuclear transport GO:0051169 4 0.018
asymmetric protein localization GO:0008105 6 0.018
positive regulation of apoptotic signaling pathway GO:2001235 1 0.018
neurological system process GO:0050877 62 0.018
hormone secretion GO:0046879 2 0.018
cellular component biogenesis GO:0044085 178 0.017
hatching GO:0035188 4 0.017
transcription dna templated GO:0006351 181 0.017
guanosine containing compound catabolic process GO:1901069 2 0.017
glycoprotein metabolic process GO:0009100 23 0.017
regulation of cellular metabolic process GO:0031323 320 0.017
vesicle mediated transport GO:0016192 22 0.017
retina layer formation GO:0010842 24 0.017
apical protein localization GO:0045176 6 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
epithelial cell morphogenesis GO:0003382 2 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
single organism membrane fusion GO:0044801 2 0.017
centrosome cycle GO:0007098 1 0.017
response to chemical GO:0042221 320 0.017
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.017
negative regulation of biological process GO:0048519 304 0.017
cell substrate adhesion GO:0031589 4 0.017
protein complex localization GO:0031503 1 0.017
response to endogenous stimulus GO:0009719 83 0.017
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.016
odontogenesis of dentin containing tooth GO:0042475 1 0.016
pole plasm assembly GO:0007315 4 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
cellular protein modification process GO:0006464 100 0.016
intracellular signal transduction GO:0035556 85 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
positive regulation of neuron death GO:1901216 1 0.016
regulation of reactive oxygen species metabolic process GO:2000377 2 0.016
regulation of protein targeting GO:1903533 2 0.016
regulation of mrna catabolic process GO:0061013 3 0.016
regulation of inflammatory response GO:0050727 2 0.016
multi organism reproductive process GO:0044703 36 0.016
tube closure GO:0060606 1 0.015
rna 3 end processing GO:0031123 2 0.015
multicellular organismal homeostasis GO:0048871 29 0.015
regulation of nitrogen compound metabolic process GO:0051171 251 0.015
organism emergence from protective structure GO:0071684 4 0.015
protein localization GO:0008104 40 0.015
extracellular structure organization GO:0043062 27 0.015
nucleic acid templated transcription GO:0097659 181 0.015
response to carbohydrate GO:0009743 3 0.015
morphogenesis of embryonic epithelium GO:0016331 30 0.015
macroautophagy GO:0016236 1 0.015
growth GO:0040007 174 0.015
nuclear import GO:0051170 3 0.015
anion transport GO:0006820 38 0.015
positive regulation of neuron apoptotic process GO:0043525 1 0.015
chordate embryonic development GO:0043009 271 0.015
blood vessel morphogenesis GO:0048514 216 0.015
negative regulation of epithelial cell proliferation GO:0050680 1 0.015
regulation of signal transduction GO:0009966 225 0.015
peptide transport GO:0015833 1 0.015
regulation of synapse assembly GO:0051963 3 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.015
gtp catabolic process GO:0006184 2 0.014
negative regulation of cellular catabolic process GO:0031330 3 0.014
eye photoreceptor cell differentiation GO:0001754 45 0.014
photoreceptor cell differentiation GO:0046530 55 0.014
neurotransmitter transport GO:0006836 2 0.014
cellular amide metabolic process GO:0043603 4 0.014
regulation of protein localization to plasma membrane GO:1903076 1 0.014
regulation of sodium ion transport GO:0002028 2 0.014
adherens junction organization GO:0034332 4 0.014
reactive oxygen species metabolic process GO:0072593 6 0.014
angiogenesis GO:0001525 158 0.014
regulation of cell shape GO:0008360 1 0.014
embryonic heart tube morphogenesis GO:0003143 108 0.014
axon development GO:0061564 166 0.014
positive regulation of cellular process GO:0048522 201 0.014
positive regulation of cytokine production GO:0001819 2 0.014
regulation of gtp catabolic process GO:0033124 2 0.014
eye pigmentation GO:0048069 4 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
response to monosaccharide GO:0034284 3 0.013
response to vitamin GO:0033273 3 0.013
camera type eye morphogenesis GO:0048593 108 0.013
lipid catabolic process GO:0016042 4 0.013
positive regulation of cell division GO:0051781 2 0.013
cellular protein catabolic process GO:0044257 4 0.013
regulation of cell death GO:0010941 103 0.013
multicellular organism reproduction GO:0032504 35 0.013
eye morphogenesis GO:0048592 144 0.013
response to organic substance GO:0010033 153 0.013
positive regulation of programmed cell death GO:0043068 29 0.013
nucleic acid metabolic process GO:0090304 244 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
notochord cell vacuolation GO:0060036 7 0.013
cognition GO:0050890 1 0.013
photoreceptor cell outer segment organization GO:0035845 9 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
mrna 3 end processing GO:0031124 2 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
ion transport GO:0006811 114 0.013
blood vessel development GO:0001568 246 0.013
Mouse
neural tube patterning GO:0021532 33 0.013
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.013
regulation of mrna processing GO:0050684 3 0.013
tissue remodeling GO:0048771 4 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
spermatid differentiation GO:0048515 2 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
gland development GO:0048732 143 0.013
hormone transport GO:0009914 2 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
regulation of neuron projection development GO:0010975 40 0.013
carbohydrate derivative metabolic process GO:1901135 61 0.012
hepaticobiliary system development GO:0061008 98 0.012
negative regulation of multi organism process GO:0043901 3 0.012
histone deacetylation GO:0016575 2 0.012
establishment of mitotic spindle localization GO:0040001 12 0.012
establishment or maintenance of apical basal cell polarity GO:0035088 12 0.012
establishment of nucleus localization GO:0040023 7 0.012
synaptic vesicle transport GO:0048489 1 0.012
gtp metabolic process GO:0046039 4 0.012
regulation of rna metabolic process GO:0051252 224 0.012
protein localization to nucleus GO:0034504 3 0.012
neural retina development GO:0003407 49 0.012
regulation of gtpase activity GO:0043087 2 0.012
skin development GO:0043588 54 0.012
gabaergic neuron differentiation GO:0097154 2 0.012
macromolecule modification GO:0043412 111 0.012
positive regulation of protein polymerization GO:0032273 2 0.012
cellular nitrogen compound metabolic process GO:0034641 290 0.012
ion transmembrane transport GO:0034220 91 0.012
phagocytosis engulfment GO:0006911 1 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
regulation of transcription dna templated GO:0006355 213 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
negative regulation of synapse assembly GO:0051964 2 0.011
cell cycle arrest GO:0007050 1 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
response to glucose GO:0009749 3 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
protein modification process GO:0036211 100 0.011
anatomical structure homeostasis GO:0060249 36 0.011
small molecule metabolic process GO:0044281 77 0.011
retinal pigment epithelium development GO:0003406 8 0.011
synaptic vesicle localization GO:0097479 1 0.011
monovalent inorganic cation transport GO:0015672 42 0.011
phosphorus metabolic process GO:0006793 109 0.011
peptidyl serine modification GO:0018209 2 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
single organism nuclear import GO:1902593 3 0.011
protein secretion GO:0009306 1 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
monoamine transport GO:0015844 1 0.011
collagen metabolic process GO:0032963 2 0.011
neuron projection morphogenesis GO:0048812 161 0.011
forebrain development GO:0030900 96 0.011
establishment of protein localization to organelle GO:0072594 4 0.011
interspecies interaction between organisms GO:0044419 4 0.011
central nervous system neuron differentiation GO:0021953 74 0.011
peripheral nervous system neuron development GO:0048935 22 0.011
tissue homeostasis GO:0001894 25 0.011
amino acid transport GO:0006865 2 0.011
heart looping GO:0001947 94 0.011
myeloid cell development GO:0061515 32 0.011
carbohydrate homeostasis GO:0033500 1 0.011
antimicrobial humoral response GO:0019730 2 0.011
peptide metabolic process GO:0006518 1 0.011
establishment of localization in cell GO:0051649 77 0.010
immune system development GO:0002520 191 0.010
inorganic cation transmembrane transport GO:0098662 50 0.010
establishment of monopolar cell polarity GO:0061162 2 0.010
embryonic epithelial tube formation GO:0001838 17 0.010
secondary metabolic process GO:0019748 3 0.010
post golgi vesicle mediated transport GO:0006892 1 0.010
multicellular organism growth GO:0035264 4 0.010
maintenance of location GO:0051235 4 0.010
regionalization GO:0003002 274 0.010
determination of heart left right asymmetry GO:0061371 117 0.010
immune system process GO:0002376 241 0.010
protein import GO:0017038 3 0.010
cell motility GO:0048870 244 0.010
mitochondrion organization GO:0007005 4 0.010
osteoclast differentiation GO:0030316 1 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010

chm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.010