Danio rerio

0 known processes

chmp4b

chromatin modifying protein 4B

(Aliases: wu:fc96b02,zgc:55566)

chmp4b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
endosomal transport GO:0016197 2 0.715
modification dependent protein catabolic process GO:0019941 3 0.363
modification dependent macromolecule catabolic process GO:0043632 3 0.293
axonogenesis GO:0007409 152 0.250
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.243
cellular protein catabolic process GO:0044257 4 0.226
receptor recycling GO:0001881 4 0.223
exocytosis GO:0006887 1 0.194
signal transduction GO:0007165 455 0.193
ubiquitin dependent protein catabolic process GO:0006511 3 0.165
cell morphogenesis involved in differentiation GO:0000904 195 0.160
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.153
regulation of response to stimulus GO:0048583 269 0.151
multi organism cellular process GO:0044764 2 0.133
positive regulation of exocytosis GO:0045921 1 0.128
heterocycle metabolic process GO:0046483 290 0.124
regulation of signal transduction GO:0009966 225 0.119
maintenance of location GO:0051235 4 0.114
single organism localization GO:1902578 225 0.109
Worm
positive regulation of transport GO:0051050 2 0.109
positive regulation of secretion by cell GO:1903532 1 0.104
transport GO:0006810 220 0.097
Worm
vacuolar transport GO:0007034 2 0.094
cell projection organization GO:0030030 284 0.092
establishment of localization GO:0051234 244 0.091
Worm
interspecies interaction between organisms GO:0044419 4 0.087
viral process GO:0016032 1 0.086
single organism metabolic process GO:0044710 217 0.086
organelle organization GO:0006996 227 0.085
Worm
proteasomal protein catabolic process GO:0010498 2 0.083
regulation of exocytosis GO:0017157 1 0.083
gene expression GO:0010467 252 0.082
regulation of filopodium assembly GO:0051489 2 0.082
larval development GO:0002164 2 0.081
Worm
protein polyubiquitination GO:0000209 4 0.081
positive regulation of secretion GO:0051047 1 0.079
cellular aromatic compound metabolic process GO:0006725 295 0.078
cell morphogenesis GO:0000902 289 0.076
organic substance biosynthetic process GO:1901576 289 0.076
cell part morphogenesis GO:0032990 246 0.075
positive regulation of cellular process GO:0048522 201 0.073
nitrogen compound metabolic process GO:0006807 319 0.071
axon development GO:0061564 166 0.070
regulation of cell projection assembly GO:0060491 4 0.070
regulation of cell maturation GO:1903429 1 0.070
cellular nitrogen compound metabolic process GO:0034641 290 0.069
establishment of protein localization to organelle GO:0072594 4 0.067
cellular macromolecule metabolic process GO:0044260 391 0.067
meiotic nuclear division GO:0007126 4 0.067
regulation of protein ubiquitination GO:0031396 3 0.065
cell projection morphogenesis GO:0048858 244 0.065
positive regulation of multi organism process GO:0043902 3 0.062
stem cell fate commitment GO:0048865 1 0.061
defense response GO:0006952 47 0.060
regulation of cell communication GO:0010646 232 0.058
regulation of neurotransmitter secretion GO:0046928 1 0.058
cellular response to starvation GO:0009267 1 0.057
positive regulation of biological process GO:0048518 253 0.056
positive regulation of cellular component biogenesis GO:0044089 3 0.056
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.055
neuron projection morphogenesis GO:0048812 161 0.054
regulation of protein complex assembly GO:0043254 3 0.054
single organism membrane fusion GO:0044801 2 0.054
cell surface receptor signaling pathway GO:0007166 325 0.052
regulation of protein catabolic process GO:0042176 1 0.052
negative regulation of cell communication GO:0010648 96 0.051
aging GO:0007568 2 0.051
Worm
generation of neurons GO:0048699 385 0.050
guanosine containing compound catabolic process GO:1901069 2 0.049
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.048
lipid storage GO:0019915 1 0.047
regulation of chromosome segregation GO:0051983 1 0.047
aromatic compound biosynthetic process GO:0019438 217 0.046
regulation of nitrogen compound metabolic process GO:0051171 251 0.046
cytokinesis GO:0000910 3 0.045
positive regulation of cellular catabolic process GO:0031331 3 0.045
regulation of biological quality GO:0065008 263 0.045
positive regulation of cellular metabolic process GO:0031325 94 0.044
regulation of macromolecule biosynthetic process GO:0010556 225 0.044
positive regulation of cytoskeleton organization GO:0051495 3 0.043
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.043
regulation of biosynthetic process GO:0009889 250 0.043
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.043
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.042
regulation of oocyte development GO:0060281 3 0.041
negative regulation of cellular process GO:0048523 283 0.041
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.040
negative regulation of response to stimulus GO:0048585 104 0.040
regulation of macromolecule metabolic process GO:0060255 317 0.040
regulation of reproductive process GO:2000241 4 0.040
cellular response to nutrient levels GO:0031669 2 0.039
developmental cell growth GO:0048588 52 0.038
multi organism process GO:0051704 134 0.038
endomembrane system organization GO:0010256 13 0.038
regulation of nucleic acid templated transcription GO:1903506 213 0.037
lytic vacuole organization GO:0080171 1 0.037
regulation of cellular metabolic process GO:0031323 320 0.037
negative regulation of signaling GO:0023057 96 0.037
single organism transport GO:0044765 206 0.036
Worm
transcription dna templated GO:0006351 181 0.036
cellular protein metabolic process GO:0044267 129 0.036
positive regulation of cell cycle GO:0045787 3 0.036
protein localization to plasma membrane GO:0072659 1 0.036
negative regulation of signal transduction GO:0009968 94 0.035
peptide transport GO:0015833 1 0.035
gliogenesis GO:0042063 45 0.035
guanosine containing compound metabolic process GO:1901068 4 0.035
macromolecule biosynthetic process GO:0009059 227 0.034
nucleobase containing compound metabolic process GO:0006139 274 0.034
cellular macromolecule biosynthetic process GO:0034645 224 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.033
cortical cytoskeleton organization GO:0030865 1 0.033
regulation of notch signaling pathway GO:0008593 16 0.033
endosome to lysosome transport GO:0008333 1 0.033
gtp metabolic process GO:0046039 4 0.033
macromolecule localization GO:0033036 54 0.033
amine metabolic process GO:0009308 2 0.032
neuron projection development GO:0031175 180 0.032
autophagy GO:0006914 4 0.032
organelle fusion GO:0048284 3 0.032
neuron differentiation GO:0030182 353 0.032
regulation of myelination GO:0031641 1 0.031
cellular localization GO:0051641 97 0.030
Worm
heterocycle biosynthetic process GO:0018130 215 0.030
cellular nitrogen compound biosynthetic process GO:0044271 218 0.030
regulation of metabolic process GO:0019222 359 0.030
regulation of primary metabolic process GO:0080090 311 0.030
organic cyclic compound biosynthetic process GO:1901362 223 0.030
biosynthetic process GO:0009058 294 0.029
cellular response to extracellular stimulus GO:0031668 2 0.029
nucleobase containing compound biosynthetic process GO:0034654 205 0.029
lysosomal transport GO:0007041 2 0.029
regulation of cell projection organization GO:0031344 44 0.029
regulation of binding GO:0051098 3 0.029
i kappab kinase nf kappab signaling GO:0007249 4 0.029
notch signaling pathway GO:0007219 35 0.029
negative regulation of biological process GO:0048519 304 0.028
single organism organelle organization GO:1902589 199 0.028
Worm
hemopoiesis GO:0030097 183 0.027
positive regulation of signaling GO:0023056 56 0.027
pole plasm assembly GO:0007315 4 0.027
cell cycle GO:0007049 93 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
transmission of nerve impulse GO:0019226 19 0.026
receptor metabolic process GO:0043112 6 0.026
neurotransmitter transport GO:0006836 2 0.025
regulation of cytoplasmic transport GO:1903649 4 0.025
neuron development GO:0048666 262 0.025
double strand break repair via homologous recombination GO:0000724 1 0.025
sensory organ development GO:0007423 393 0.024
protein targeting to nucleus GO:0044744 3 0.024
nucleic acid templated transcription GO:0097659 181 0.024
regulation of multicellular organismal development GO:2000026 223 0.023
regulation of signaling GO:0023051 235 0.023
cellular amine metabolic process GO:0044106 2 0.023
organic cyclic compound metabolic process GO:1901360 301 0.023
vesicle organization GO:0016050 6 0.023
cellular component biogenesis GO:0044085 178 0.023
Worm
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.023
anterior posterior pattern specification GO:0009952 152 0.022
intracellular transport GO:0046907 32 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
response to external stimulus GO:0009605 264 0.022
gtp catabolic process GO:0006184 2 0.022
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.022
macromolecule modification GO:0043412 111 0.022
rna metabolic process GO:0016070 219 0.021
meiotic cell cycle process GO:1903046 3 0.021
negative regulation of protein transport GO:0051224 3 0.021
regulation of receptor recycling GO:0001919 3 0.020
regulation of cellular protein catabolic process GO:1903362 1 0.020
cellular response to external stimulus GO:0071496 2 0.020
embryo development ending in birth or egg hatching GO:0009792 271 0.019
Worm
protein import into nucleus GO:0006606 3 0.019
neurotransmitter secretion GO:0007269 2 0.019
membrane fusion GO:0061025 2 0.019
protein metabolic process GO:0019538 183 0.019
rna biosynthetic process GO:0032774 181 0.018
positive regulation of catabolic process GO:0009896 4 0.018
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.018
regulation of cell shape GO:0008360 1 0.018
regulation of localization GO:0032879 104 0.018
regulation of synaptic vesicle transport GO:1902803 1 0.018
regulation of neurotransmitter transport GO:0051588 1 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
regulation of rna metabolic process GO:0051252 224 0.018
protein import GO:0017038 3 0.018
protein localization to nucleus GO:0034504 3 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
interaction with host GO:0051701 4 0.017
cytoskeleton dependent cytokinesis GO:0061640 3 0.017
response to chemical GO:0042221 320 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
regulation of cellular component size GO:0032535 30 0.017
skeletal system morphogenesis GO:0048705 102 0.017
cytoskeleton organization GO:0007010 96 0.017
Worm
cellular response to molecule of bacterial origin GO:0071219 3 0.017
regionalization GO:0003002 274 0.017
negative regulation of mitosis GO:0045839 3 0.017
establishment of localization in cell GO:0051649 77 0.017
Worm
proteolysis GO:0006508 38 0.017
intracellular signal transduction GO:0035556 85 0.016
actin polymerization or depolymerization GO:0008154 2 0.016
actin mediated cell contraction GO:0070252 1 0.016
single organism nuclear import GO:1902593 3 0.016
regulation of cytokine production GO:0001817 3 0.016
enzyme linked receptor protein signaling pathway GO:0007167 106 0.016
meiotic chromosome segregation GO:0045132 3 0.016
negative regulation of secretion GO:0051048 2 0.016
stem cell maintenance GO:0019827 4 0.016
synaptic vesicle localization GO:0097479 1 0.016
regulation of wound healing GO:0061041 2 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
locomotion GO:0040011 313 0.015
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 9 0.015
cytoplasm organization GO:0007028 4 0.015
ribose phosphate metabolic process GO:0019693 27 0.015
regulation of microtubule cytoskeleton organization GO:0070507 3 0.015
regulation of transcription dna templated GO:0006355 213 0.015
developmental growth involved in morphogenesis GO:0060560 86 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
cell cycle process GO:0022402 53 0.015
nucleic acid metabolic process GO:0090304 244 0.015
regulation of protein transport GO:0051223 3 0.015
cellular biosynthetic process GO:0044249 286 0.015
protein localization to vacuole GO:0072665 1 0.015
small molecule metabolic process GO:0044281 77 0.015
regulation of protein targeting GO:1903533 2 0.014
positive regulation of reproductive process GO:2000243 2 0.014
ras protein signal transduction GO:0007265 7 0.014
single organism intracellular transport GO:1902582 25 0.014
protein k48 linked ubiquitination GO:0070936 1 0.014
mitotic recombination GO:0006312 2 0.014
developmental maturation GO:0021700 34 0.014
cell division GO:0051301 20 0.014
cellular component movement GO:0006928 335 0.014
regulation of cellular component organization GO:0051128 86 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
regulation of tube size GO:0035150 2 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
leukocyte mediated cytotoxicity GO:0001909 1 0.014
regulation of gtp catabolic process GO:0033124 2 0.014
regulation of embryonic development GO:0045995 47 0.014
endosome organization GO:0007032 2 0.013
compound eye development GO:0048749 2 0.013
wound healing GO:0042060 90 0.013
regulation of transport GO:0051049 45 0.013
regulation of locomotion GO:0040012 55 0.013
regulation of anatomical structure size GO:0090066 33 0.013
localization of cell GO:0051674 244 0.013
synaptic vesicle transport GO:0048489 1 0.013
regulation of developmental process GO:0050793 247 0.013
positive regulation of signal transduction GO:0009967 56 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
hormone secretion GO:0046879 2 0.013
regulation of ras gtpase activity GO:0032318 2 0.013
cellular component assembly GO:0022607 170 0.013
Worm
regulation of gtpase activity GO:0043087 2 0.013
cellular response to organic substance GO:0071310 105 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
cellular protein modification process GO:0006464 100 0.013
female meiotic division GO:0007143 2 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
vesicle mediated transport GO:0016192 22 0.012
Worm
apoptotic process GO:0006915 116 0.012
microtubule cytoskeleton organization GO:0000226 33 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
catabolic process GO:0009056 32 0.012
protein secretion GO:0009306 1 0.012
phosphorylation GO:0016310 69 0.012
single organism membrane organization GO:0044802 20 0.012
double strand break repair GO:0006302 3 0.012
somatic stem cell maintenance GO:0035019 1 0.012
response to xenobiotic stimulus GO:0009410 45 0.012
microtubule based process GO:0007017 60 0.012
developmental growth GO:0048589 166 0.012
tissue remodeling GO:0048771 4 0.012
glial cell migration GO:0008347 3 0.012
endocrine process GO:0050886 2 0.012
proximal distal pattern formation GO:0009954 1 0.012
negative regulation of multi organism process GO:0043901 3 0.012
regulation of molecular function GO:0065009 70 0.012
oocyte maturation GO:0001556 4 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
histone modification GO:0016570 20 0.011
negative regulation of nuclear division GO:0051784 3 0.011
peripheral nervous system development GO:0007422 55 0.011
somatic muscle development GO:0007525 4 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
cellular macromolecule catabolic process GO:0044265 12 0.011
nuclear transport GO:0051169 4 0.011
mitotic cytokinesis GO:0000281 3 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
female meiosis chromosome segregation GO:0016321 1 0.011
regulation of cell activation GO:0050865 1 0.011
skeletal system development GO:0001501 181 0.011
rna localization GO:0006403 4 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
cellular macromolecular complex assembly GO:0034622 24 0.011
Worm
neuroblast proliferation GO:0007405 2 0.011
regulation of cell differentiation GO:0045595 142 0.011
cortical actin cytoskeleton organization GO:0030866 1 0.010
macromolecular complex subunit organization GO:0043933 74 0.010
Worm
regulation of intracellular signal transduction GO:1902531 57 0.010
regulation of mapk cascade GO:0043408 14 0.010
response to extracellular stimulus GO:0009991 10 0.010
regulation of muscle contraction GO:0006937 3 0.010
positive regulation of protein metabolic process GO:0051247 23 0.010
multicellular organismal signaling GO:0035637 22 0.010

chmp4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.037
disease of anatomical entity DOID:7 0 0.037
disease of metabolism DOID:0014667 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
gastrointestinal system cancer DOID:3119 0 0.010
organ system cancer DOID:0050686 0 0.010