Danio rerio

0 known processes

ckmb

creatine kinase, muscle b

(Aliases: wu:fb55e09,MGC92070,zgc:92070,zgc:64204,ckm3,MGC64204)

ckmb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 271 0.389
aging GO:0007568 2 0.381
heart development GO:0007507 313 0.377
cellular component assembly GO:0022607 170 0.301
single organism biosynthetic process GO:0044711 71 0.270
Mouse Rat
ventricular cardiac myofibril assembly GO:0055005 4 0.254
neuromuscular synaptic transmission GO:0007274 2 0.251
striated muscle cell differentiation GO:0051146 129 0.242
embryonic heart tube development GO:0035050 133 0.241
tube morphogenesis GO:0035239 349 0.241
positive regulation of nucleoside metabolic process GO:0045979 1 0.197
organophosphate biosynthetic process GO:0090407 23 0.191
Mouse Rat
cellular component morphogenesis GO:0032989 336 0.191
single organism organelle organization GO:1902589 199 0.169
oxoacid metabolic process GO:0043436 31 0.168
Mouse Rat
maintenance of location GO:0051235 4 0.162
single organism localization GO:1902578 225 0.160
muscle cell development GO:0055001 115 0.159
cellular component biogenesis GO:0044085 178 0.150
organic acid metabolic process GO:0006082 31 0.149
Mouse Rat
nitrogen compound metabolic process GO:0006807 319 0.148
Mouse Rat
regulation of biological quality GO:0065008 263 0.146
phosphorus metabolic process GO:0006793 109 0.143
Mouse Rat
larval development GO:0002164 2 0.134
system process GO:0003008 185 0.128
lipid storage GO:0019915 1 0.124
chordate embryonic development GO:0043009 271 0.120
regulation of nucleoside metabolic process GO:0009118 2 0.117
regulation of ion transmembrane transporter activity GO:0032412 2 0.112
striated muscle cell development GO:0055002 108 0.109
blood circulation GO:0008015 87 0.109
muscle cell differentiation GO:0042692 139 0.108
cellular modified amino acid metabolic process GO:0006575 3 0.108
Mouse Rat
organonitrogen compound biosynthetic process GO:1901566 47 0.100
Mouse Rat
nucleobase containing compound metabolic process GO:0006139 274 0.096
positive regulation of biological process GO:0048518 253 0.094
ventricular cardiac muscle cell development GO:0055015 5 0.094
regulation of heart contraction GO:0008016 32 0.092
cellular biosynthetic process GO:0044249 286 0.091
Mouse Rat
single organism metabolic process GO:0044710 217 0.088
Mouse Rat
actomyosin structure organization GO:0031032 53 0.087
embryonic organ development GO:0048568 381 0.087
organic acid catabolic process GO:0016054 3 0.087
cytoskeleton organization GO:0007010 96 0.086
response to external stimulus GO:0009605 264 0.085
regulation of cellular metabolic process GO:0031323 320 0.085
angiogenesis GO:0001525 158 0.084
adult behavior GO:0030534 2 0.084
small molecule catabolic process GO:0044282 3 0.082
single organism transport GO:0044765 206 0.081
establishment of localization GO:0051234 244 0.081
response to stress GO:0006950 263 0.081
positive regulation of cellular catabolic process GO:0031331 3 0.080
determination of heart left right asymmetry GO:0061371 117 0.080
small molecule metabolic process GO:0044281 77 0.079
Mouse Rat
reactive nitrogen species metabolic process GO:2001057 0 0.079
response to chemical GO:0042221 320 0.079
organelle organization GO:0006996 227 0.077
organic cyclic compound metabolic process GO:1901360 301 0.075
heart morphogenesis GO:0003007 156 0.074
transport GO:0006810 220 0.073
cardiocyte differentiation GO:0035051 44 0.072
heart process GO:0003015 71 0.072
regulation of transmembrane transporter activity GO:0022898 2 0.072
circulatory system process GO:0003013 87 0.071
cellular nitrogen compound metabolic process GO:0034641 290 0.070
regulation of purine nucleotide catabolic process GO:0033121 2 0.070
heart looping GO:0001947 94 0.070
biosynthetic process GO:0009058 294 0.068
Mouse Rat
regulation of metabolic process GO:0019222 359 0.068
organelle assembly GO:0070925 110 0.067
regulation of sequestering of calcium ion GO:0051282 4 0.066
cellular amino acid metabolic process GO:0006520 7 0.066
Mouse Rat
organic substance biosynthetic process GO:1901576 289 0.065
Mouse Rat
negative regulation of cellular process GO:0048523 283 0.065
cell projection morphogenesis GO:0048858 244 0.061
positive regulation of catabolic process GO:0009896 4 0.061
muscle structure development GO:0061061 196 0.061
cellular amino acid biosynthetic process GO:0008652 2 0.061
Mouse Rat
epithelial tube morphogenesis GO:0060562 148 0.059
atp catabolic process GO:0006200 4 0.059
regulation of transmembrane transport GO:0034762 18 0.057
heterocycle metabolic process GO:0046483 290 0.055
purine nucleoside monophosphate catabolic process GO:0009128 4 0.055
negative regulation of biological process GO:0048519 304 0.053
inorganic ion transmembrane transport GO:0098660 57 0.053
regulation of primary metabolic process GO:0080090 311 0.052
fatty acid beta oxidation GO:0006635 1 0.051
segmentation GO:0035282 97 0.051
embryonic heart tube morphogenesis GO:0003143 108 0.051
er nucleus signaling pathway GO:0006984 2 0.050
actin cytoskeleton organization GO:0030036 63 0.050
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.050
lipid oxidation GO:0034440 1 0.049
phosphate containing compound metabolic process GO:0006796 108 0.048
Mouse Rat
cellular component assembly involved in morphogenesis GO:0010927 107 0.048
regulation of membrane potential GO:0042391 23 0.048
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.048
cardiac muscle cell differentiation GO:0055007 30 0.048
regulation of multicellular organismal process GO:0051239 277 0.047
heterocycle biosynthetic process GO:0018130 215 0.046
positive regulation of transport GO:0051050 2 0.046
heart contraction GO:0060047 71 0.046
cytokinesis GO:0000910 3 0.046
ribonucleoside monophosphate catabolic process GO:0009158 4 0.045
homeostatic process GO:0042592 142 0.045
digestive tract development GO:0048565 265 0.044
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.043
regulation of metal ion transport GO:0010959 4 0.042
morphogenesis of an epithelium GO:0002009 333 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.042
sensory organ development GO:0007423 393 0.042
immune system development GO:0002520 191 0.042
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.041
purine nucleotide metabolic process GO:0006163 27 0.041
cellular response to unfolded protein GO:0034620 2 0.041
sequestering of calcium ion GO:0051208 3 0.040
determination of bilateral symmetry GO:0009855 204 0.040
response to organic substance GO:0010033 153 0.040
water homeostasis GO:0030104 4 0.040
regulation of macromolecule metabolic process GO:0060255 317 0.040
mitotic cytokinesis GO:0000281 3 0.039
lipid catabolic process GO:0016042 4 0.039
regulation of nucleotide catabolic process GO:0030811 2 0.039
protein localization to nucleus GO:0034504 3 0.037
nucleocytoplasmic transport GO:0006913 4 0.037
regulation of cytoplasmic transport GO:1903649 4 0.036
nucleoside biosynthetic process GO:0009163 2 0.036
regulation of protein polymerization GO:0032271 2 0.035
positive regulation of blood circulation GO:1903524 2 0.035
sequestering of metal ion GO:0051238 3 0.035
actin filament based process GO:0030029 64 0.035
regulation of reproductive process GO:2000241 4 0.035
cellular component maintenance GO:0043954 3 0.035
carboxylic acid catabolic process GO:0046395 3 0.034
myofibril assembly GO:0030239 48 0.034
endoplasmic reticulum unfolded protein response GO:0030968 2 0.034
embryonic organ morphogenesis GO:0048562 274 0.034
axonogenesis GO:0007409 152 0.033
regulation of signal transduction GO:0009966 225 0.033
regulation of protein complex assembly GO:0043254 3 0.033
endocardial cushion morphogenesis GO:0003203 3 0.033
death GO:0016265 121 0.032
protein import GO:0017038 3 0.032
regulation of cell shape GO:0008360 1 0.032
single organism nuclear import GO:1902593 3 0.032
ribonucleotide metabolic process GO:0009259 27 0.032
purine ribonucleotide biosynthetic process GO:0009152 20 0.032
muscle system process GO:0003012 20 0.031
ion transmembrane transport GO:0034220 91 0.031
ion transport GO:0006811 114 0.031
regulation of calcium ion transport GO:0051924 2 0.030
ventricular cardiac muscle cell differentiation GO:0055012 6 0.030
determination of left right symmetry GO:0007368 179 0.030
cellular component movement GO:0006928 335 0.030
response to abiotic stimulus GO:0009628 122 0.030
regulation of transporter activity GO:0032409 2 0.030
establishment of protein localization to organelle GO:0072594 4 0.030
head development GO:0060322 303 0.030
protein metabolic process GO:0019538 183 0.029
cell substrate adhesion GO:0031589 4 0.029
chemical homeostasis GO:0048878 49 0.029
ion homeostasis GO:0050801 41 0.029
calcium ion transport into cytosol GO:0060402 3 0.029
neurological system process GO:0050877 62 0.028
organonitrogen compound metabolic process GO:1901564 74 0.028
Mouse Rat
cell morphogenesis GO:0000902 289 0.028
regulation of nitrogen compound metabolic process GO:0051171 251 0.028
protein import into nucleus GO:0006606 3 0.028
cellular aromatic compound metabolic process GO:0006725 295 0.027
carboxylic acid metabolic process GO:0019752 22 0.027
Mouse Rat
multi organism process GO:0051704 134 0.027
regulation of muscle contraction GO:0006937 3 0.027
fatty acid catabolic process GO:0009062 1 0.027
cellular nitrogen compound biosynthetic process GO:0044271 218 0.027
cellular response to chemical stimulus GO:0070887 157 0.027
eye development GO:0001654 277 0.027
purine containing compound biosynthetic process GO:0072522 20 0.027
macromolecule localization GO:0033036 54 0.026
carbohydrate derivative biosynthetic process GO:1901137 43 0.026
protein targeting to nucleus GO:0044744 3 0.026
endocardial cushion formation GO:0003272 2 0.026
programmed cell death GO:0012501 119 0.026
regulation of purine nucleotide metabolic process GO:1900542 17 0.026
specification of symmetry GO:0009799 204 0.025
regulation of multicellular organismal development GO:2000026 223 0.025
transmembrane transport GO:0055085 120 0.025
locomotion GO:0040011 313 0.025
cellular lipid catabolic process GO:0044242 3 0.025
regionalization GO:0003002 274 0.025
positive regulation of molecular function GO:0044093 33 0.025
nucleoside monophosphate catabolic process GO:0009125 4 0.025
regulation of mrna processing GO:0050684 3 0.025
mesoderm development GO:0007498 88 0.024
hematopoietic stem cell differentiation GO:0060218 20 0.024
monocarboxylic acid catabolic process GO:0072329 3 0.024
negative regulation of protein complex assembly GO:0031333 1 0.024
ubiquitin dependent protein catabolic process GO:0006511 3 0.024
kidney development GO:0001822 92 0.024
carbohydrate derivative metabolic process GO:1901135 61 0.023
regulation of cell substrate adhesion GO:0010810 1 0.023
multicellular organism growth GO:0035264 4 0.023
regulation of biosynthetic process GO:0009889 250 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.023
organic cyclic compound biosynthetic process GO:1901362 223 0.023
pronephros development GO:0048793 69 0.023
pyruvate metabolic process GO:0006090 1 0.023
organophosphate metabolic process GO:0019637 37 0.023
Mouse Rat
sarcomere organization GO:0045214 26 0.023
cellular response to organic substance GO:0071310 105 0.022
modification dependent protein catabolic process GO:0019941 3 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
generation of neurons GO:0048699 385 0.022
response to other organism GO:0051707 97 0.022
signal transduction GO:0007165 455 0.022
blood vessel development GO:0001568 246 0.022
striated muscle contraction GO:0006941 12 0.022
positive regulation of nucleotide catabolic process GO:0030813 1 0.022
regulation of protein import into nucleus GO:0042306 2 0.022
regulation of system process GO:0044057 40 0.022
cardiac cell development GO:0055006 21 0.022
establishment of synaptic vesicle localization GO:0097480 1 0.021
nitric oxide biosynthetic process GO:0006809 2 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.021
somitogenesis GO:0001756 87 0.021
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.021
metal ion transport GO:0030001 58 0.021
central nervous system development GO:0007417 387 0.021
actin filament polymerization GO:0030041 2 0.021
response to mechanical stimulus GO:0009612 24 0.020
nucleoside triphosphate biosynthetic process GO:0009142 2 0.020
nucleobase containing compound biosynthetic process GO:0034654 205 0.020
regulation of signaling GO:0023051 235 0.020
positive regulation of heart contraction GO:0045823 2 0.020
pigmentation GO:0043473 85 0.020
cell part morphogenesis GO:0032990 246 0.020
regulation of programmed cell death GO:0043067 101 0.019
anterior posterior pattern specification GO:0009952 152 0.019
regulation of phosphate metabolic process GO:0019220 43 0.019
regulation of cell death GO:0010941 103 0.019
vasculature development GO:0001944 278 0.019
cellular localization GO:0051641 97 0.019
mitochondrion organization GO:0007005 4 0.019
mesenchyme development GO:0060485 127 0.019
positive regulation of cellular metabolic process GO:0031325 94 0.019
gtp metabolic process GO:0046039 4 0.019
development of primary female sexual characteristics GO:0046545 4 0.019
lymphoid lineage cell migration GO:0097534 4 0.019
cellular response to stress GO:0033554 62 0.019
protein polymerization GO:0051258 4 0.019
calcium ion homeostasis GO:0055074 19 0.018
aromatic compound biosynthetic process GO:0019438 217 0.018
calcium ion import GO:0070509 4 0.018
cytoskeleton dependent cytokinesis GO:0061640 3 0.018
biological adhesion GO:0022610 40 0.018
muscle contraction GO:0006936 18 0.018
regulation of developmental process GO:0050793 247 0.018
regulation of cell projection assembly GO:0060491 4 0.018
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.018
cellular lipid metabolic process GO:0044255 36 0.018
regulation of binding GO:0051098 3 0.018
nuclear transport GO:0051169 4 0.017
negative regulation of kinase activity GO:0033673 4 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.017
carbohydrate metabolic process GO:0005975 12 0.017
actin polymerization or depolymerization GO:0008154 2 0.017
regulation of cell communication GO:0010646 232 0.017
response to external biotic stimulus GO:0043207 97 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
mitotic cell cycle GO:0000278 64 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
nuclear import GO:0051170 3 0.017
regulation of phosphorus metabolic process GO:0051174 43 0.017
stem cell differentiation GO:0048863 117 0.017
gene expression GO:0010467 252 0.017
blood vessel morphogenesis GO:0048514 216 0.016
hemopoiesis GO:0030097 183 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.016
germ cell development GO:0007281 22 0.016
apoptotic process GO:0006915 116 0.016
response to unfolded protein GO:0006986 2 0.016
regulation of tube size GO:0035150 2 0.016
establishment of vesicle localization GO:0051650 24 0.016
regulation of apoptotic process GO:0042981 98 0.016
ribose phosphate metabolic process GO:0019693 27 0.016
rna metabolic process GO:0016070 219 0.016
cellular chemical homeostasis GO:0055082 17 0.015
action potential GO:0001508 19 0.015
cellular macromolecule metabolic process GO:0044260 391 0.015
positive regulation of cellular process GO:0048522 201 0.015
regulation of intracellular signal transduction GO:1902531 57 0.015
ribose phosphate biosynthetic process GO:0046390 20 0.015
digestive system development GO:0055123 289 0.015
purine ribonucleoside biosynthetic process GO:0046129 2 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
rna biosynthetic process GO:0032774 181 0.015
vesicle localization GO:0051648 27 0.015
neuron development GO:0048666 262 0.015
response to topologically incorrect protein GO:0035966 2 0.015
protein complex assembly GO:0006461 30 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.014
defense response GO:0006952 47 0.014
cell motility GO:0048870 244 0.014
axon development GO:0061564 166 0.014
stem cell proliferation GO:0072089 4 0.014
meiotic nuclear division GO:0007126 4 0.014
organelle localization GO:0051640 49 0.014
regulation of ion transmembrane transport GO:0034765 18 0.014
regulation of protein transport GO:0051223 3 0.014
regulation of cell matrix adhesion GO:0001952 1 0.014
single organism reproductive process GO:0044702 40 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.014
small molecule biosynthetic process GO:0044283 16 0.014
Mouse Rat
nucleotide biosynthetic process GO:0009165 21 0.014
divalent inorganic cation homeostasis GO:0072507 22 0.014
regulation of protein complex disassembly GO:0043244 1 0.014
protein polyubiquitination GO:0000209 4 0.014
regulation of cell development GO:0060284 100 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
protein localization GO:0008104 40 0.013
response to carbohydrate GO:0009743 3 0.013
regulation of macromolecule biosynthetic process GO:0010556 225 0.013
lipid metabolic process GO:0006629 52 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
endoderm development GO:0007492 49 0.013
immune system process GO:0002376 241 0.013
reactive oxygen species biosynthetic process GO:1903409 1 0.013
female sex differentiation GO:0046660 4 0.013
striated muscle tissue development GO:0014706 110 0.013
cellular response to hormone stimulus GO:0032870 39 0.013
basement membrane assembly GO:0070831 3 0.013
developmental growth GO:0048589 166 0.013
lipid biosynthetic process GO:0008610 22 0.013
membrane repolarization GO:0086009 2 0.013
purine ribonucleotide metabolic process GO:0009150 27 0.013
cellular amine metabolic process GO:0044106 2 0.013
regulation of homeostatic process GO:0032844 9 0.013
organic acid biosynthetic process GO:0016053 12 0.013
Mouse Rat
cell migration GO:0016477 237 0.013
adherens junction organization GO:0034332 4 0.013
cellular response to external stimulus GO:0071496 2 0.013
regulation of blood vessel size GO:0050880 2 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
regulation of nitric oxide mediated signal transduction GO:0010749 1 0.013
regulation of blood circulation GO:1903522 32 0.012
regulation of catalytic activity GO:0050790 55 0.012
cell matrix adhesion GO:0007160 4 0.012
regulation of hydrolase activity GO:0051336 28 0.012
ras protein signal transduction GO:0007265 7 0.012
chemotaxis GO:0006935 104 0.012
mitotic cell cycle process GO:1903047 48 0.012
nucleobase containing small molecule metabolic process GO:0055086 32 0.012
purine containing compound metabolic process GO:0072521 29 0.012
intracellular signal transduction GO:0035556 85 0.012
regulation of striated muscle contraction GO:0006942 2 0.012
cell death GO:0008219 121 0.012
specification of axis polarity GO:0065001 4 0.012
regulation of cytokine mediated signaling pathway GO:0001959 3 0.012
cellular cation homeostasis GO:0030003 17 0.012
response to drug GO:0042493 3 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.012
behavior GO:0007610 74 0.012
regulation of localization GO:0032879 104 0.012
ventricular cardiac muscle tissue development GO:0003229 3 0.011
monocarboxylic acid metabolic process GO:0032787 17 0.011
regulation of cellular component size GO:0032535 30 0.011
protein complex disassembly GO:0043241 1 0.011
metal ion homeostasis GO:0055065 26 0.011
nucleic acid metabolic process GO:0090304 244 0.011
regulation of ion transport GO:0043269 22 0.011
cation homeostasis GO:0055080 33 0.011
atrial cardiac myofibril assembly GO:0055004 2 0.011
cytokine mediated signaling pathway GO:0019221 7 0.011
phosphorylation GO:0016310 69 0.011
Mouse Rat
organic substance transport GO:0071702 58 0.011
regulation of molecular function GO:0065009 70 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
cell junction maintenance GO:0034331 2 0.011
organelle fusion GO:0048284 3 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
neuroblast proliferation GO:0007405 2 0.011
somatic muscle development GO:0007525 4 0.011
taxis GO:0042330 109 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.011
macromolecular complex disassembly GO:0032984 1 0.011
cellular protein catabolic process GO:0044257 4 0.011
catabolic process GO:0009056 32 0.011
multi organism reproductive process GO:0044703 36 0.010
reactive oxygen species metabolic process GO:0072593 6 0.010
establishment of blood brain barrier GO:0060856 2 0.010
ribonucleotide biosynthetic process GO:0009260 20 0.010
regulation of p38mapk cascade GO:1900744 1 0.010
neuron cellular homeostasis GO:0070050 3 0.010
purine nucleotide biosynthetic process GO:0006164 20 0.010
cellular macromolecule biosynthetic process GO:0034645 224 0.010
single organism cellular localization GO:1902580 46 0.010

ckmb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
musculoskeletal system disease DOID:17 0 0.017
distal arthrogryposis DOID:0050646 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011