Danio rerio

0 known processes

clasp2

cytoplasmic linker associated protein 2

(Aliases: MGC77279,zgc:77279)

clasp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.180
cell surface receptor signaling pathway GO:0007166 325 0.128
organelle organization GO:0006996 227 0.124
Human Mouse Worm Fly
negative regulation of biological process GO:0048519 304 0.112
Mouse Fly
regulation of intracellular protein transport GO:0033157 3 0.112
regulation of protein import into nucleus GO:0042306 2 0.107
regulation of protein transport GO:0051223 3 0.103
protein localization to nucleus GO:0034504 3 0.099
localization of cell GO:0051674 244 0.098
Mouse Fly
protein import into nucleus GO:0006606 3 0.087
regulation of biological quality GO:0065008 263 0.078
Human Worm Fly
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.076
regulation of protein targeting GO:1903533 2 0.073
single organism nuclear import GO:1902593 3 0.072
regulation of protein localization to nucleus GO:1900180 2 0.070
regulation of cellular metabolic process GO:0031323 320 0.068
peptidyl lysine acetylation GO:0018394 2 0.065
positive regulation of catabolic process GO:0009896 4 0.065
locomotion GO:0040011 313 0.065
Mouse Worm Fly
larval development GO:0002164 2 0.064
Worm
regulation of protein complex assembly GO:0043254 3 0.064
single organism metabolic process GO:0044710 217 0.064
nuclear import GO:0051170 3 0.060
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.059
establishment of protein localization to organelle GO:0072594 4 0.059
transport GO:0006810 220 0.058
Worm
meiotic nuclear division GO:0007126 4 0.058
regulation of establishment of protein localization GO:0070201 4 0.057
cellular protein catabolic process GO:0044257 4 0.056
cell motility GO:0048870 244 0.056
Mouse Fly
nuclear transport GO:0051169 4 0.056
regulation of nucleocytoplasmic transport GO:0046822 2 0.056
nitrogen compound metabolic process GO:0006807 319 0.055
protein targeting to nucleus GO:0044744 3 0.054
nucleocytoplasmic transport GO:0006913 4 0.054
internal peptidyl lysine acetylation GO:0018393 2 0.054
protein import GO:0017038 3 0.053
negative regulation of cytoplasmic transport GO:1903650 2 0.053
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.053
positive regulation of transport GO:0051050 2 0.051
regulation of cytoplasmic transport GO:1903649 4 0.051
cellular response to radiation GO:0071478 4 0.050
regulation of signal transduction GO:0009966 225 0.050
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.050
cellular response to external stimulus GO:0071496 2 0.049
locomotor rhythm GO:0045475 3 0.049
negative regulation of intracellular transport GO:0032387 3 0.049
regulation of macromolecule metabolic process GO:0060255 317 0.048
positive regulation of cellular component biogenesis GO:0044089 3 0.048
cell migration GO:0016477 237 0.048
Mouse Fly
protein acetylation GO:0006473 2 0.048
protein polymerization GO:0051258 4 0.047
Human
positive regulation of cellular catabolic process GO:0031331 3 0.045
ubiquitin dependent protein catabolic process GO:0006511 3 0.045
cellular biosynthetic process GO:0044249 286 0.043
protein acylation GO:0043543 3 0.043
cellular response to light stimulus GO:0071482 4 0.043
response to uv GO:0009411 3 0.042
regulation of cell activation GO:0050865 1 0.041
regulation of metabolic process GO:0019222 359 0.041
regulation of reproductive process GO:2000241 4 0.041
apoptotic process GO:0006915 116 0.041
signal transduction GO:0007165 455 0.039
Fly
cellular component morphogenesis GO:0032989 336 0.039
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.038
negative regulation of tor signaling GO:0032007 2 0.038
peptidyl serine phosphorylation GO:0018105 1 0.038
protein k48 linked ubiquitination GO:0070936 1 0.037
peptidyl threonine phosphorylation GO:0018107 1 0.037
single organism organelle organization GO:1902589 199 0.037
Human Mouse Worm Fly
biosynthetic process GO:0009058 294 0.036
neuron differentiation GO:0030182 353 0.036
Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.036
Fly
maintenance of location GO:0051235 4 0.035
Human Worm Fly
positive regulation of cellular amine metabolic process GO:0033240 0 0.035
amine metabolic process GO:0009308 2 0.035
internal protein amino acid acetylation GO:0006475 2 0.035
cellular component movement GO:0006928 335 0.034
Mouse Fly
heterocycle metabolic process GO:0046483 290 0.033
regulation of cell shape GO:0008360 1 0.032
neuron development GO:0048666 262 0.032
Fly
single organism localization GO:1902578 225 0.032
Human Worm Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.030
death GO:0016265 121 0.030
response to organic substance GO:0010033 153 0.030
negative regulation of intracellular protein transport GO:0090317 3 0.030
protein polyubiquitination GO:0000209 4 0.030
somatic muscle development GO:0007525 4 0.030
regulation of catalytic activity GO:0050790 55 0.029
peptidyl serine modification GO:0018209 2 0.029
regulation of cellular biosynthetic process GO:0031326 245 0.029
regulation of neurological system process GO:0031644 2 0.029
negative regulation of catabolic process GO:0009895 3 0.029
rna transport GO:0050658 2 0.029
regulation of multicellular organism growth GO:0040014 4 0.029
Worm
regulation of cellular amine metabolic process GO:0033238 0 0.029
intracellular estrogen receptor signaling pathway GO:0030520 3 0.028
immune system development GO:0002520 191 0.028
Fly
regulation of response to extracellular stimulus GO:0032104 1 0.028
generation of neurons GO:0048699 385 0.027
Fly
regulation of protein catabolic process GO:0042176 1 0.027
positive regulation of cellular process GO:0048522 201 0.027
modification dependent macromolecule catabolic process GO:0043632 3 0.027
proteasomal protein catabolic process GO:0010498 2 0.027
meiotic chromosome segregation GO:0045132 3 0.027
cell death GO:0008219 121 0.027
regulation of primary metabolic process GO:0080090 311 0.027
meiotic cell cycle process GO:1903046 3 0.027
cellular component biogenesis GO:0044085 178 0.027
Human Fly
regulation of biosynthetic process GO:0009889 250 0.027
negative regulation of protein import into nucleus GO:0042308 2 0.026
organic substance biosynthetic process GO:1901576 289 0.026
carboxylic acid metabolic process GO:0019752 22 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
cellular macromolecule metabolic process GO:0044260 391 0.026
cellular component disassembly GO:0022411 1 0.026
Mouse Fly
negative regulation of cellular process GO:0048523 283 0.026
Mouse Fly
regulation of programmed cell death GO:0043067 101 0.026
cellular ketone metabolic process GO:0042180 11 0.026
oxoacid metabolic process GO:0043436 31 0.025
regulation of cellular ketone metabolic process GO:0010565 7 0.024
multi organism process GO:0051704 134 0.024
Fly
programmed cell death GO:0012501 119 0.024
negative regulation of map kinase activity GO:0043407 2 0.024
response to carbohydrate GO:0009743 3 0.023
response to chemical GO:0042221 320 0.023
Fly
regulation of apoptotic process GO:0042981 98 0.023
mitotic dna integrity checkpoint GO:0044774 4 0.023
acylglycerol homeostasis GO:0055090 2 0.023
response to stress GO:0006950 263 0.023
peptide transport GO:0015833 1 0.022
modification dependent protein catabolic process GO:0019941 3 0.022
regulation of dna templated transcription elongation GO:0032784 3 0.022
chromosome organization GO:0051276 31 0.022
Worm Fly
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.022
macromolecule biosynthetic process GO:0009059 227 0.022
regulation of transcription dna templated GO:0006355 213 0.022
negative regulation of macromolecule metabolic process GO:0010605 76 0.022
development of primary female sexual characteristics GO:0046545 4 0.022
regulation of response to stimulus GO:0048583 269 0.022
Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.021
cell part morphogenesis GO:0032990 246 0.021
Fly
cellular amino acid metabolic process GO:0006520 7 0.021
response to hormone GO:0009725 48 0.021
system process GO:0003008 185 0.021
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.021
cellular response to extracellular stimulus GO:0031668 2 0.021
regulation of cytokine production GO:0001817 3 0.021
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.021
cellular localization GO:0051641 97 0.021
Human Worm Fly
cellular response to chemical stimulus GO:0070887 157 0.020
single organism reproductive process GO:0044702 40 0.020
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.020
Fly
rna localization GO:0006403 4 0.020
cellular protein metabolic process GO:0044267 129 0.020
cell matrix adhesion GO:0007160 4 0.020
female gonad development GO:0008585 4 0.020
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.020
cellular response to nutrient levels GO:0031669 2 0.020
developmental maturation GO:0021700 34 0.020
Fly
negative regulation of protein complex assembly GO:0031333 1 0.019
hatching GO:0035188 4 0.019
negative regulation of cell communication GO:0010648 96 0.019
Fly
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
organic acid metabolic process GO:0006082 31 0.019
response to glucose GO:0009749 3 0.019
regulation of cell communication GO:0010646 232 0.019
Fly
cellular amine metabolic process GO:0044106 2 0.019
astral microtubule organization GO:0030953 1 0.019
Worm
regulation of signaling GO:0023051 235 0.019
Fly
response to endogenous stimulus GO:0009719 83 0.019
intracellular signal transduction GO:0035556 85 0.019
Fly
lipid storage GO:0019915 1 0.019
small molecule catabolic process GO:0044282 3 0.019
negative regulation of protein transport GO:0051224 3 0.018
response to abiotic stimulus GO:0009628 122 0.018
regulation of synapse assembly GO:0051963 3 0.018
positive regulation of biological process GO:0048518 253 0.018
Worm
rna biosynthetic process GO:0032774 181 0.018
regulation of cellular component movement GO:0051270 55 0.018
regulation of dna recombination GO:0000018 2 0.018
response to radiation GO:0009314 51 0.018
positive regulation of cell activation GO:0050867 1 0.018
dorsal ventral pattern formation GO:0009953 125 0.018
autophagy GO:0006914 4 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
peptidyl threonine modification GO:0018210 1 0.018
gene expression GO:0010467 252 0.018
dna templated transcription elongation GO:0006354 3 0.017
regulation of cell death GO:0010941 103 0.017
regulation of protein polymerization GO:0032271 2 0.017
regulation of jak stat cascade GO:0046425 3 0.017
response to nutrient GO:0007584 3 0.017
positive regulation of gene expression GO:0010628 71 0.017
meiosis i GO:0007127 1 0.017
meiotic spindle organization GO:0000212 1 0.017
cell projection organization GO:0030030 284 0.017
Fly
cellular response to organic substance GO:0071310 105 0.017
regulation of response to nutrient levels GO:0032107 1 0.017
histone lysine demethylation GO:0070076 2 0.017
nucleobase containing compound metabolic process GO:0006139 274 0.017
response to hexose GO:0009746 3 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
sleep GO:0030431 1 0.017
double strand break repair via homologous recombination GO:0000724 1 0.017
regulation of gene expression GO:0010468 265 0.017
negative regulation of cellular catabolic process GO:0031330 3 0.016
lamellipodium organization GO:0097581 1 0.016
negative regulation of signal transduction GO:0009968 94 0.016
Fly
positive regulation of notch signaling pathway GO:0045747 3 0.016
positive regulation of myeloid cell differentiation GO:0045639 2 0.016
regulation of organelle assembly GO:1902115 4 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
single organism transport GO:0044765 206 0.016
cytoskeleton organization GO:0007010 96 0.016
Human Mouse Worm Fly
protein metabolic process GO:0019538 183 0.016
regionalization GO:0003002 274 0.016
pole plasm assembly GO:0007315 4 0.016
organism emergence from protective structure GO:0071684 4 0.016
actin filament polymerization GO:0030041 2 0.016
stem cell division GO:0017145 1 0.016
glial cell proliferation GO:0014009 4 0.016
negative regulation of cellular metabolic process GO:0031324 77 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
g2 dna damage checkpoint GO:0031572 3 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
response to drug GO:0042493 3 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
Worm
cell substrate adhesion GO:0031589 4 0.015
protein demethylation GO:0006482 2 0.015
neurotransmitter secretion GO:0007269 2 0.015
regulation of dendrite development GO:0050773 3 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
rna metabolic process GO:0016070 219 0.015
taxis GO:0042330 109 0.015
Fly
endosomal transport GO:0016197 2 0.015
regulation of autophagy GO:0010506 3 0.015
hemopoiesis GO:0030097 183 0.014
Fly
regulation of gtp catabolic process GO:0033124 2 0.014
homeostatic process GO:0042592 142 0.014
axon development GO:0061564 166 0.014
Fly
stem cell maintenance GO:0019827 4 0.014
Fly
immune system process GO:0002376 241 0.014
Fly
negative regulation of protein phosphorylation GO:0001933 4 0.014
small molecule metabolic process GO:0044281 77 0.014
regulation of protein depolymerization GO:1901879 1 0.014
Mouse Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
histone demethylation GO:0016577 2 0.014
nuclear export GO:0051168 1 0.014
olfactory lobe development GO:0021988 4 0.014
negative regulation of signaling GO:0023057 96 0.014
Fly
multicellular organism growth GO:0035264 4 0.014
Worm
regulation of synaptic plasticity GO:0048167 1 0.014
cell substrate junction assembly GO:0007044 2 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.014
chromatin organization GO:0006325 22 0.014
mitochondrion organization GO:0007005 4 0.014
actin polymerization or depolymerization GO:0008154 2 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
protein complex localization GO:0031503 1 0.014
regulation of gtpase activity GO:0043087 2 0.014
rna 3 end processing GO:0031123 2 0.014
establishment of rna localization GO:0051236 3 0.014
regulation of cell matrix adhesion GO:0001952 1 0.014
regulation of organ growth GO:0046620 3 0.014
meiosis ii GO:0007135 1 0.013
lamellipodium assembly GO:0030032 1 0.013
response to external stimulus GO:0009605 264 0.013
Fly
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
positive regulation of jak stat cascade GO:0046427 2 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
cellular protein modification process GO:0006464 100 0.013
digestive tract development GO:0048565 265 0.013
regulation of mrna processing GO:0050684 3 0.013
erythrocyte differentiation GO:0030218 54 0.013
gtp catabolic process GO:0006184 2 0.013
negative regulation of metabolic process GO:0009892 86 0.013
cellular aromatic compound metabolic process GO:0006725 295 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
regulation of glial cell proliferation GO:0060251 4 0.013
neuron projection development GO:0031175 180 0.013
Fly
regulation of chromosome segregation GO:0051983 1 0.013
nucleic acid transport GO:0050657 2 0.013
organic cyclic compound metabolic process GO:1901360 301 0.013
response to alkaloid GO:0043279 2 0.013
regulation of localization GO:0032879 104 0.013
response to vitamin GO:0033273 3 0.013
response to monosaccharide GO:0034284 3 0.012
mrna stabilization GO:0048255 4 0.012
response to light stimulus GO:0009416 46 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
response to lipid GO:0033993 60 0.012
sexual reproduction GO:0019953 36 0.012
Fly
vacuolar transport GO:0007034 2 0.012
cytoplasm organization GO:0007028 4 0.012
female sex differentiation GO:0046660 4 0.012
gtp metabolic process GO:0046039 4 0.012
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
digestive system development GO:0055123 289 0.012
triglyceride homeostasis GO:0070328 2 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
inner ear development GO:0048839 126 0.012
tetrapyrrole metabolic process GO:0033013 10 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
embryonic organ development GO:0048568 381 0.012
Fly
microtubule organizing center organization GO:0031023 1 0.012
Human Fly
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
developmental programmed cell death GO:0010623 4 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
mitotic nuclear division GO:0007067 18 0.012
Worm Fly
negative regulation of kinase activity GO:0033673 4 0.012
establishment of localization GO:0051234 244 0.012
Worm Fly
axonogenesis GO:0007409 152 0.012
Fly
apoptotic process involved in development GO:1902742 2 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
hepaticobiliary system development GO:0061008 98 0.011
negative regulation of multi organism process GO:0043901 3 0.011
protein modification process GO:0036211 100 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.011
regulation of cell motility GO:2000145 46 0.011
centrosome organization GO:0051297 1 0.011
Fly
positive regulation of cytoskeleton organization GO:0051495 3 0.011
protein dealkylation GO:0008214 2 0.011
nucleobase containing compound transport GO:0015931 2 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
response to wounding GO:0009611 116 0.011
regulation of locomotion GO:0040012 55 0.011
positive regulation of leukocyte differentiation GO:1902107 1 0.011
response to fatty acid GO:0070542 5 0.011
cellular component assembly GO:0022607 170 0.011
Human Fly
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
positive regulation of cell cycle GO:0045787 3 0.011
response to growth factor GO:0070848 39 0.011
lysosomal transport GO:0007041 2 0.011
spindle assembly GO:0051225 2 0.011
Fly
mitotic dna damage checkpoint GO:0044773 4 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
negative regulation of protein localization to nucleus GO:1900181 2 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
neurological system process GO:0050877 62 0.011
negative regulation of ras protein signal transduction GO:0046580 1 0.011
Fly
mitotic g2 dna damage checkpoint GO:0007095 3 0.011
neuron remodeling GO:0016322 1 0.011
glucose homeostasis GO:0042593 1 0.011
synaptic vesicle endocytosis GO:0048488 1 0.010
cell projection morphogenesis GO:0048858 244 0.010
Fly
amino acid transport GO:0006865 2 0.010
regulation of nucleotide catabolic process GO:0030811 2 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
Fly
growth GO:0040007 174 0.010
Worm
tissue remodeling GO:0048771 4 0.010
regulation of oocyte development GO:0060281 3 0.010
alcohol biosynthetic process GO:0046165 2 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
production of molecular mediator of immune response GO:0002440 2 0.010
negative regulation of cell death GO:0060548 60 0.010
leukocyte proliferation GO:0070661 1 0.010
gamete generation GO:0007276 33 0.010
Fly
nuclear migration GO:0007097 3 0.010
blood circulation GO:0008015 87 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010

clasp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
organ system cancer DOID:0050686 0 0.027
disease of anatomical entity DOID:7 0 0.017