Danio rerio

26 known processes

cldne

claudin e

(Aliases: fb16e12,cb84,wu:fb16e12)

cldne biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transport GO:0006811 114 0.746
Zebrafish
establishment of localization GO:0051234 244 0.674
Zebrafish
sensory organ development GO:0007423 393 0.590
Zebrafish
single organism transport GO:0044765 206 0.455
Zebrafish
transport GO:0006810 220 0.446
Zebrafish
gene expression GO:0010467 252 0.320
positive regulation of cellular process GO:0048522 201 0.306
tube morphogenesis GO:0035239 349 0.285
regulation of biosynthetic process GO:0009889 250 0.282
response to chemical GO:0042221 320 0.264
regulation of cellular biosynthetic process GO:0031326 245 0.261
response to hexose GO:0009746 3 0.247
cellular response to external stimulus GO:0071496 2 0.208
establishment of endothelial barrier GO:0061028 3 0.200
Zebrafish
nuclear transport GO:0051169 4 0.193
lateral line system development GO:0048925 76 0.192
Zebrafish
cell motility GO:0048870 244 0.184
digestive tract development GO:0048565 265 0.182
organic acid metabolic process GO:0006082 31 0.155
negative regulation of protein transport GO:0051224 3 0.140
transcription from rna polymerase ii promoter GO:0006366 80 0.133
keratinocyte differentiation GO:0030216 0 0.132
pigmentation GO:0043473 85 0.130
leukocyte homeostasis GO:0001776 2 0.128
single organism localization GO:1902578 225 0.125
Zebrafish
lateral line development GO:0048882 66 0.124
Zebrafish
chordate embryonic development GO:0043009 271 0.123
organic substance transport GO:0071702 58 0.123
multicellular organismal water homeostasis GO:0050891 1 0.120
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.120
digestive system development GO:0055123 289 0.116
response to organic substance GO:0010033 153 0.116
aging GO:0007568 2 0.116
cellular response to starvation GO:0009267 1 0.113
gastrulation GO:0007369 208 0.113
endothelial cell development GO:0001885 12 0.110
Zebrafish
anion transport GO:0006820 38 0.109
endothelium development GO:0003158 25 0.108
Zebrafish
water homeostasis GO:0030104 4 0.107
oxoacid metabolic process GO:0043436 31 0.106
establishment of skin barrier GO:0061436 1 0.105
regulation of primary metabolic process GO:0080090 311 0.105
cell proliferation GO:0008283 80 0.104
biosynthetic process GO:0009058 294 0.103
protein secretion GO:0009306 1 0.103
epithelial cell differentiation GO:0030855 116 0.102
Zebrafish
regulation of protein transport GO:0051223 3 0.097
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.097
phagocytosis GO:0006909 3 0.097
odontogenesis of dentin containing tooth GO:0042475 1 0.096
positive regulation of cell cycle GO:0045787 3 0.096
regulation of macromolecule metabolic process GO:0060255 317 0.093
positive regulation of gene expression GO:0010628 71 0.092
fin regeneration GO:0031101 51 0.092
organic anion transport GO:0015711 15 0.090
rna biosynthetic process GO:0032774 181 0.087
establishment of protein localization to organelle GO:0072594 4 0.087
signal transduction GO:0007165 455 0.086
response to stress GO:0006950 263 0.084
regulation of establishment of protein localization GO:0070201 4 0.084
cellular component movement GO:0006928 335 0.083
nucleobase containing compound biosynthetic process GO:0034654 205 0.083
immune system process GO:0002376 241 0.082
response to external stimulus GO:0009605 264 0.081
apical junction assembly GO:0043297 1 0.081
cellular response to extracellular stimulus GO:0031668 2 0.081
regulation of synaptic plasticity GO:0048167 1 0.080
regulation of nucleic acid templated transcription GO:1903506 213 0.078
nucleic acid metabolic process GO:0090304 244 0.078
response to wounding GO:0009611 116 0.077
positive regulation of biological process GO:0048518 253 0.077
cellular macromolecule metabolic process GO:0044260 391 0.077
mitotic cell cycle process GO:1903047 48 0.076
sensory system development GO:0048880 76 0.076
Zebrafish
death GO:0016265 121 0.075
regulation of cellular metabolic process GO:0031323 320 0.075
regulation of gene expression GO:0010468 265 0.073
embryonic organ development GO:0048568 381 0.072
regulation of nitrogen compound metabolic process GO:0051171 251 0.071
monovalent inorganic cation transport GO:0015672 42 0.070
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.069
small molecule metabolic process GO:0044281 77 0.068
positive regulation of transport GO:0051050 2 0.068
regulation of rna biosynthetic process GO:2001141 213 0.066
regulation of transcription dna templated GO:0006355 213 0.065
organelle organization GO:0006996 227 0.062
nitrogen compound metabolic process GO:0006807 319 0.061
regulation of water loss via skin GO:0033561 1 0.061
epidermis development GO:0008544 48 0.060
cell cycle g1 s phase transition GO:0044843 1 0.060
lipid digestion GO:0044241 3 0.059
fatty acid transport GO:0015908 1 0.058
regulation of sodium ion transport GO:0002028 2 0.057
Zebrafish
cellular response to nutrient levels GO:0031669 2 0.056
digestive tract morphogenesis GO:0048546 231 0.055
t cell activation GO:0042110 6 0.054
apoptotic process GO:0006915 116 0.053
long chain fatty acid transport GO:0015909 1 0.053
gastrulation with mouth forming second GO:0001702 44 0.051
regulation of cytokine production GO:0001817 3 0.050
embryo development ending in birth or egg hatching GO:0009792 271 0.049
tissue regeneration GO:0042246 74 0.047
localization of cell GO:0051674 244 0.047
autophagy GO:0006914 4 0.047
inner ear development GO:0048839 126 0.046
system process GO:0003008 185 0.045
transcription dna templated GO:0006351 181 0.045
organic cyclic compound metabolic process GO:1901360 301 0.044
organic substance biosynthetic process GO:1901576 289 0.044
brain development GO:0007420 293 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.043
cell migration involved in heart development GO:0060973 22 0.043
response to glucocorticoid GO:0051384 1 0.043
morphogenesis of an epithelial fold GO:0060571 1 0.043
organelle fusion GO:0048284 3 0.042
larval development GO:0002164 2 0.041
cellular localization GO:0051641 97 0.041
regulation of metabolic process GO:0019222 359 0.041
regulation of developmental process GO:0050793 247 0.040
regulation of cell proliferation GO:0042127 37 0.040
carboxylic acid metabolic process GO:0019752 22 0.040
cell migration GO:0016477 237 0.039
positive regulation of cell adhesion GO:0045785 1 0.038
embryonic skeletal system morphogenesis GO:0048704 93 0.036
skeletal system development GO:0001501 181 0.036
single organism behavior GO:0044708 24 0.036
ear development GO:0043583 127 0.036
regulation of rna metabolic process GO:0051252 224 0.036
cellular response to chemical stimulus GO:0070887 157 0.036
positive regulation of metabolic process GO:0009893 108 0.035
growth GO:0040007 174 0.035
heart development GO:0007507 313 0.035
regulation of blood pressure GO:0008217 1 0.035
response to carbohydrate GO:0009743 3 0.034
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.034
cellular protein metabolic process GO:0044267 129 0.033
fatty acid biosynthetic process GO:0006633 4 0.033
meiotic chromosome segregation GO:0045132 3 0.033
cellular amino acid metabolic process GO:0006520 7 0.033
morphogenesis of an epithelium GO:0002009 333 0.033
negative regulation of biological process GO:0048519 304 0.033
regulation of autophagy GO:0010506 3 0.033
cellular nitrogen compound biosynthetic process GO:0044271 218 0.032
response to drug GO:0042493 3 0.032
response to monosaccharide GO:0034284 3 0.031
epidermal cell differentiation GO:0009913 36 0.031
protein metabolic process GO:0019538 183 0.031
phagocytosis engulfment GO:0006911 1 0.031
multi organism process GO:0051704 134 0.031
cellular component assembly involved in morphogenesis GO:0010927 107 0.030
hematopoietic or lymphoid organ development GO:0048534 191 0.029
regulation of photoreceptor cell differentiation GO:0046532 2 0.029
positive regulation of cellular biosynthetic process GO:0031328 68 0.029
metal ion transport GO:0030001 58 0.029
Zebrafish
positive regulation of cellular metabolic process GO:0031325 94 0.029
regulation of transport GO:0051049 45 0.028
Zebrafish
defense response GO:0006952 47 0.028
regulation of macromolecule biosynthetic process GO:0010556 225 0.028
lymphocyte activation GO:0046649 10 0.028
alpha amino acid metabolic process GO:1901605 3 0.028
cation transport GO:0006812 81 0.028
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.028
cellular response to organic substance GO:0071310 105 0.028
leukocyte proliferation GO:0070661 1 0.028
endothelial cell differentiation GO:0045446 20 0.028
Zebrafish
neurological system process GO:0050877 62 0.027
membrane organization GO:0061024 21 0.027
regulation of inflammatory response GO:0050727 2 0.027
response to uv GO:0009411 3 0.027
specification of symmetry GO:0009799 204 0.027
macromolecule biosynthetic process GO:0009059 227 0.027
multicellular organismal homeostasis GO:0048871 29 0.027
response to biotic stimulus GO:0009607 97 0.027
nuclear export GO:0051168 1 0.027
endocytosis GO:0006897 16 0.026
rna metabolic process GO:0016070 219 0.026
nucleic acid templated transcription GO:0097659 181 0.026
cell death GO:0008219 121 0.025
cell cycle process GO:0022402 53 0.025
hemopoiesis GO:0030097 183 0.025
tissue remodeling GO:0048771 4 0.025
regulation of intracellular protein transport GO:0033157 3 0.025
sensory perception of pain GO:0019233 1 0.025
regulation of apoptotic process GO:0042981 98 0.025
organic acid transport GO:0015849 9 0.025
aromatic compound biosynthetic process GO:0019438 217 0.025
negative regulation of epithelial cell proliferation GO:0050680 1 0.024
positive regulation of translation GO:0045727 1 0.024
membrane fusion GO:0061025 2 0.024
otic placode formation GO:0043049 23 0.024
mononuclear cell proliferation GO:0032943 1 0.023
myeloid cell homeostasis GO:0002262 56 0.023
cellular component biogenesis GO:0044085 178 0.023
wound healing GO:0042060 90 0.023
positive regulation of rna metabolic process GO:0051254 59 0.023
negative regulation of multicellular organismal process GO:0051241 69 0.023
developmental growth GO:0048589 166 0.023
cellular nitrogen compound metabolic process GO:0034641 290 0.023
response to lipid GO:0033993 60 0.023
cellular aromatic compound metabolic process GO:0006725 295 0.023
cell morphogenesis GO:0000902 289 0.023
cell cycle GO:0007049 93 0.023
regionalization GO:0003002 274 0.022
mechanosensory lateral line system development GO:0048881 49 0.022
nucleocytoplasmic transport GO:0006913 4 0.022
regulation of cell activation GO:0050865 1 0.022
cellular protein modification process GO:0006464 100 0.022
reactive oxygen species biosynthetic process GO:1903409 1 0.022
epiboly GO:0090504 41 0.022
striated muscle tissue development GO:0014706 110 0.022
appendage morphogenesis GO:0035107 56 0.021
meiotic nuclear division GO:0007126 4 0.021
protein modification process GO:0036211 100 0.021
regulation of dna templated transcription in response to stress GO:0043620 0 0.021
protein import GO:0017038 3 0.021
positive regulation of rna biosynthetic process GO:1902680 57 0.021
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.020
central nervous system development GO:0007417 387 0.020
epithelial cell development GO:0002064 42 0.020
Zebrafish
macroautophagy GO:0016236 1 0.020
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.020
regulation of multicellular organismal process GO:0051239 277 0.020
cognition GO:0050890 1 0.020
cell surface receptor signaling pathway GO:0007166 325 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
regulation of biological quality GO:0065008 263 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
oocyte maturation GO:0001556 4 0.019
s adenosylmethionine metabolic process GO:0046500 1 0.019
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 9 0.019
female gonad development GO:0008585 4 0.019
response to molecule of bacterial origin GO:0002237 14 0.018
peptide transport GO:0015833 1 0.018
vasculature development GO:0001944 278 0.018
lymphocyte proliferation GO:0046651 1 0.018
morphogenesis of an epithelial sheet GO:0002011 49 0.018
meiotic cell cycle process GO:1903046 3 0.018
regulation of cellular component movement GO:0051270 55 0.018
hatching GO:0035188 4 0.018
leukocyte migration GO:0050900 15 0.018
regulation of protein metabolic process GO:0051246 56 0.017
membrane invagination GO:0010324 1 0.017
ectodermal cell fate specification GO:0001715 2 0.017
single organism membrane organization GO:0044802 20 0.017
urogenital system development GO:0001655 97 0.017
embryonic skeletal joint morphogenesis GO:0060272 3 0.017
mitotic cell cycle GO:0000278 64 0.017
single organism membrane fusion GO:0044801 2 0.017
response to external biotic stimulus GO:0043207 97 0.017
regulation of ion transport GO:0043269 22 0.017
Zebrafish
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.017
response to other organism GO:0051707 97 0.016
negative regulation of cytokine production GO:0001818 1 0.016
positive regulation of cell death GO:0010942 29 0.016
lipid catabolic process GO:0016042 4 0.016
intestinal epithelial cell differentiation GO:0060575 3 0.016
single organism organelle organization GO:1902589 199 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
modification dependent protein catabolic process GO:0019941 3 0.016
response to cytokine GO:0034097 7 0.016
macromolecule modification GO:0043412 111 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
protein localization to plasma membrane GO:0072659 1 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
regulation of cellular protein metabolic process GO:0032268 52 0.015
behavior GO:0007610 74 0.015
response to lipopolysaccharide GO:0032496 13 0.015
homeostatic process GO:0042592 142 0.015
negative regulation of defense response GO:0031348 2 0.015
response to corticosteroid GO:0031960 1 0.015
neuromast development GO:0048884 46 0.015
Zebrafish
cardiac muscle cell differentiation GO:0055007 30 0.015
regulation of localization GO:0032879 104 0.015
Zebrafish
single organism metabolic process GO:0044710 217 0.015
regeneration GO:0031099 91 0.015
regulation of programmed cell death GO:0043067 101 0.015
positive regulation of transcription dna templated GO:0045893 57 0.015
regulation of mitotic cell cycle GO:0007346 25 0.015
small gtpase mediated signal transduction GO:0007264 8 0.015
negative regulation of cellular process GO:0048523 283 0.015
catechol containing compound biosynthetic process GO:0009713 2 0.014
monocarboxylic acid metabolic process GO:0032787 17 0.014
intestinal absorption GO:0050892 2 0.014
regulation of response to stimulus GO:0048583 269 0.014
cytoskeleton organization GO:0007010 96 0.014
heterocycle metabolic process GO:0046483 290 0.014
negative regulation of secretion by cell GO:1903531 2 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
amine metabolic process GO:0009308 2 0.014
establishment of protein localization to plasma membrane GO:0090002 1 0.014
programmed cell death GO:0012501 119 0.014
regulation of dna templated transcription elongation GO:0032784 3 0.014
positive regulation of chromosome organization GO:2001252 1 0.014
sympathetic nervous system development GO:0048485 3 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.013
monocarboxylic acid transport GO:0015718 5 0.013
taxis GO:0042330 109 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
regulation of cell differentiation GO:0045595 142 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
cellular ketone metabolic process GO:0042180 11 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
nuclear import GO:0051170 3 0.013
smooth muscle contraction GO:0006939 2 0.013
regulation of molecular function GO:0065009 70 0.013
locomotion GO:0040011 313 0.013
homeostasis of number of cells GO:0048872 62 0.012
cell projection organization GO:0030030 284 0.012
protein acetylation GO:0006473 2 0.012
negative regulation of granulocyte chemotaxis GO:0071623 3 0.012
nitric oxide mediated signal transduction GO:0007263 2 0.012
embryonic skeletal system development GO:0048706 97 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
response to oxygen containing compound GO:1901700 55 0.012
cell maturation GO:0048469 23 0.012
calcium independent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016338 1 0.012
Mouse
female gamete generation GO:0007292 14 0.012
regulation of response to external stimulus GO:0032101 31 0.011
endocardial cushion formation GO:0003272 2 0.011
regulation of muscle contraction GO:0006937 3 0.011
cardiac cell development GO:0055006 21 0.011
response to steroid hormone GO:0048545 35 0.011
response to starvation GO:0042594 5 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
regulation of kinase activity GO:0043549 15 0.011
embryonic heart tube development GO:0035050 133 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 6 0.011
Mouse
endomembrane system organization GO:0010256 13 0.011
immune system development GO:0002520 191 0.011
stem cell maintenance GO:0019827 4 0.011
nitrogen compound transport GO:0071705 23 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.010
negative regulation of cellular biosynthetic process GO:0031327 55 0.010
hormone transport GO:0009914 2 0.010
positive regulation of biosynthetic process GO:0009891 68 0.010
intracellular signal transduction GO:0035556 85 0.010
erythrocyte differentiation GO:0030218 54 0.010
regulation of cell motility GO:2000145 46 0.010
chemical homeostasis GO:0048878 49 0.010
embryonic skeletal joint development GO:0072498 3 0.010
regulation of body fluid levels GO:0050878 16 0.010
negative regulation of secretion GO:0051048 2 0.010

cldne disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
integumentary system disease DOID:16 0 0.015