Danio rerio

0 known processes

cldng

claudin g

(Aliases: zgc:152655,cb214,MGC136312,zgc:136312)

cldng biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of metabolic process GO:0019222 359 0.537
oocyte maturation GO:0001556 4 0.462
homeostatic process GO:0042592 142 0.358
hematopoietic or lymphoid organ development GO:0048534 191 0.356
negative regulation of cellular process GO:0048523 283 0.354
digestive tract development GO:0048565 265 0.305
Zebrafish
tube morphogenesis GO:0035239 349 0.301
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.297
aromatic compound biosynthetic process GO:0019438 217 0.289
ion transport GO:0006811 114 0.285
Zebrafish
cellular aromatic compound metabolic process GO:0006725 295 0.258
biosynthetic process GO:0009058 294 0.257
embryonic organ development GO:0048568 381 0.250
single organism metabolic process GO:0044710 217 0.242
fatty acid elongation unsaturated fatty acid GO:0019368 1 0.234
sensory organ development GO:0007423 393 0.206
Zebrafish
long chain fatty acid biosynthetic process GO:0042759 1 0.197
nitrogen compound metabolic process GO:0006807 319 0.195
organic cyclic compound metabolic process GO:1901360 301 0.172
morphogenesis of an epithelium GO:0002009 333 0.169
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.168
epithelial cell differentiation GO:0030855 116 0.167
Zebrafish
oocyte development GO:0048599 14 0.164
gastrulation with mouth forming second GO:0001702 44 0.161
Zebrafish
immune system process GO:0002376 241 0.151
heterocycle biosynthetic process GO:0018130 215 0.141
immune system development GO:0002520 191 0.140
regulation of nucleic acid templated transcription GO:1903506 213 0.139
digestive tract morphogenesis GO:0048546 231 0.139
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.136
small molecule metabolic process GO:0044281 77 0.135
larval development GO:0002164 2 0.134
superoxide metabolic process GO:0006801 2 0.132
cellular nitrogen compound metabolic process GO:0034641 290 0.131
regulation of signaling GO:0023051 235 0.124
transcription dna templated GO:0006351 181 0.123
regulation of embryonic development GO:0045995 47 0.120
cellular amine metabolic process GO:0044106 2 0.117
locomotion GO:0040011 313 0.116
regulation of response to stimulus GO:0048583 269 0.114
transcription from rna polymerase ii promoter GO:0006366 80 0.111
embryo development ending in birth or egg hatching GO:0009792 271 0.108
regulation of developmental process GO:0050793 247 0.106
nucleic acid metabolic process GO:0090304 244 0.105
regulation of primary metabolic process GO:0080090 311 0.104
hemopoiesis GO:0030097 183 0.104
tissue remodeling GO:0048771 4 0.103
gene expression GO:0010467 252 0.102
regulation of biosynthetic process GO:0009889 250 0.099
rna biosynthetic process GO:0032774 181 0.099
regulation of cellular metabolic process GO:0031323 320 0.099
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.096
Zebrafish
heart looping GO:0001947 94 0.094
regulation of biological quality GO:0065008 263 0.094
inner ear development GO:0048839 126 0.093
macromolecule biosynthetic process GO:0009059 227 0.091
regulation of rna biosynthetic process GO:2001141 213 0.091
digestive system development GO:0055123 289 0.090
Zebrafish
epithelial tube morphogenesis GO:0060562 148 0.090
determination of heart left right asymmetry GO:0061371 117 0.088
response to external stimulus GO:0009605 264 0.087
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.086
positive regulation of cell cycle GO:0045787 3 0.086
multi organism process GO:0051704 134 0.081
determination of left right symmetry GO:0007368 179 0.081
regulation of cellular biosynthetic process GO:0031326 245 0.081
heterocycle metabolic process GO:0046483 290 0.081
embryonic heart tube development GO:0035050 133 0.081
gastrulation GO:0007369 208 0.078
Zebrafish
iron ion transmembrane transport GO:0034755 3 0.074
developmental maturation GO:0021700 34 0.074
regulation of nitrogen compound metabolic process GO:0051171 251 0.073
reproductive process GO:0022414 40 0.073
bmp signaling pathway GO:0030509 52 0.071
aging GO:0007568 2 0.070
regulation of signal transduction GO:0009966 225 0.068
single organism biosynthetic process GO:0044711 71 0.068
nucleobase containing compound metabolic process GO:0006139 274 0.067
ear development GO:0043583 127 0.066
organonitrogen compound metabolic process GO:1901564 74 0.066
stem cell maintenance GO:0019827 4 0.065
response to biotic stimulus GO:0009607 97 0.065
regulation of cysteine type endopeptidase activity GO:2000116 21 0.065
cell migration GO:0016477 237 0.064
positive regulation of molecular function GO:0044093 33 0.064
cell fate commitment GO:0045165 99 0.063
organic substance biosynthetic process GO:1901576 289 0.062
cell fate specification GO:0001708 68 0.061
negative regulation of gene expression GO:0010629 65 0.060
morphogenesis of an epithelial sheet GO:0002011 49 0.059
Zebrafish
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.059
signal transduction GO:0007165 455 0.059
negative regulation of multicellular organismal process GO:0051241 69 0.058
erythrocyte differentiation GO:0030218 54 0.058
regulation of reproductive process GO:2000241 4 0.058
embryonic hemopoiesis GO:0035162 53 0.058
single organism localization GO:1902578 225 0.058
Zebrafish
oocyte differentiation GO:0009994 14 0.057
regulation of macromolecule metabolic process GO:0060255 317 0.057
establishment of localization GO:0051234 244 0.056
Zebrafish
cell motility GO:0048870 244 0.055
regulation of bmp signaling pathway GO:0030510 39 0.055
positive regulation of cellular metabolic process GO:0031325 94 0.054
cellular nitrogen compound biosynthetic process GO:0044271 218 0.054
regulation of endopeptidase activity GO:0052548 23 0.053
determination of bilateral symmetry GO:0009855 204 0.052
heart development GO:0007507 313 0.051
response to stress GO:0006950 263 0.050
regulation of peptidase activity GO:0052547 23 0.050
amine metabolic process GO:0009308 2 0.049
positive regulation of neural precursor cell proliferation GO:2000179 1 0.047
regulation of multicellular organismal development GO:2000026 223 0.047
regulation of macromolecule biosynthetic process GO:0010556 225 0.047
regionalization GO:0003002 274 0.047
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.046
regulation of metal ion transport GO:0010959 4 0.046
Zebrafish
lipid metabolic process GO:0006629 52 0.046
cation transport GO:0006812 81 0.046
Zebrafish
nuclear transport GO:0051169 4 0.046
maintenance of location GO:0051235 4 0.044
formation of primary germ layer GO:0001704 62 0.043
transmembrane transport GO:0055085 120 0.043
neuromast development GO:0048884 46 0.043
Zebrafish
positive regulation of metabolic process GO:0009893 108 0.042
regulation of molecular function GO:0065009 70 0.042
cell cell recognition GO:0009988 1 0.042
cellular carbohydrate metabolic process GO:0044262 4 0.042
myeloid cell development GO:0061515 32 0.041
cell surface receptor signaling pathway GO:0007166 325 0.041
rna metabolic process GO:0016070 219 0.041
regulation of catalytic activity GO:0050790 55 0.040
single organism transport GO:0044765 206 0.039
Zebrafish
innate immune response GO:0045087 13 0.039
cell proliferation GO:0008283 80 0.039
central nervous system development GO:0007417 387 0.039
negative regulation of mitosis GO:0045839 3 0.039
negative regulation of signaling GO:0023057 96 0.039
cellular macromolecule metabolic process GO:0044260 391 0.038
embryonic heart tube morphogenesis GO:0003143 108 0.038
alcohol biosynthetic process GO:0046165 2 0.038
positive regulation of transport GO:0051050 2 0.037
regulation of oocyte development GO:0060281 3 0.037
regulation of rna metabolic process GO:0051252 224 0.036
response to drug GO:0042493 3 0.036
chordate embryonic development GO:0043009 271 0.036
multicellular organismal reproductive process GO:0048609 35 0.036
phosphorus metabolic process GO:0006793 109 0.036
death GO:0016265 121 0.036
regulation of myotube differentiation GO:0010830 2 0.036
negative regulation of cytokine production GO:0001818 1 0.036
myeloid cell differentiation GO:0030099 86 0.035
cation homeostasis GO:0055080 33 0.035
bmp signaling pathway involved in heart jogging GO:0003303 14 0.035
ear morphogenesis GO:0042471 64 0.035
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.035
regulation of phosphorus metabolic process GO:0051174 43 0.034
spemann organizer formation at the embryonic shield GO:0060063 2 0.034
bmp signaling pathway involved in heart development GO:0061312 15 0.034
neuron development GO:0048666 262 0.034
dopamine biosynthetic process GO:0042416 2 0.034
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.033
generation of neurons GO:0048699 385 0.033
erythrocyte maturation GO:0043249 8 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.033
negative regulation of reproductive process GO:2000242 3 0.033
enzyme linked receptor protein signaling pathway GO:0007167 106 0.033
regulation of binding GO:0051098 3 0.032
cellular component movement GO:0006928 335 0.032
protein metabolic process GO:0019538 183 0.032
organonitrogen compound biosynthetic process GO:1901566 47 0.032
pancreas development GO:0031016 84 0.032
cellular ketone metabolic process GO:0042180 11 0.032
negative regulation of biological process GO:0048519 304 0.031
positive regulation of cellular catabolic process GO:0031331 3 0.031
phagocytosis GO:0006909 3 0.031
axis specification GO:0009798 43 0.031
regulation of cell communication GO:0010646 232 0.031
very long chain fatty acid biosynthetic process GO:0042761 4 0.031
transport GO:0006810 220 0.031
Zebrafish
regulation of programmed cell death GO:0043067 101 0.031
regulation of gene expression GO:0010468 265 0.030
response to organic substance GO:0010033 153 0.030
regulation of protein complex assembly GO:0043254 3 0.030
anterior posterior pattern specification GO:0009952 152 0.029
organelle organization GO:0006996 227 0.029
metal ion transport GO:0030001 58 0.029
Zebrafish
cellular response to external stimulus GO:0071496 2 0.029
cellular biosynthetic process GO:0044249 286 0.029
specification of symmetry GO:0009799 204 0.029
stem cell division GO:0017145 1 0.029
striated muscle cell development GO:0055002 108 0.029
reproduction GO:0000003 40 0.029
embryonic organ morphogenesis GO:0048562 274 0.029
regulation of cytokine production GO:0001817 3 0.029
cell maturation GO:0048469 23 0.028
cellular localization GO:0051641 97 0.028
neural precursor cell proliferation GO:0061351 20 0.028
multicellular organism growth GO:0035264 4 0.028
mesenchyme development GO:0060485 127 0.028
intracellular estrogen receptor signaling pathway GO:0030520 3 0.028
iron ion homeostasis GO:0055072 4 0.028
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.027
inner ear morphogenesis GO:0042472 63 0.027
proteolysis GO:0006508 38 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.027
neuroblast proliferation GO:0007405 2 0.027
negative regulation of cell differentiation GO:0045596 46 0.027
response to glucocorticoid GO:0051384 1 0.027
cellular response to biotic stimulus GO:0071216 3 0.027
heart contraction GO:0060047 71 0.027
positive regulation of translation GO:0045727 1 0.027
response to bacterium GO:0009617 58 0.027
cellular macromolecule biosynthetic process GO:0034645 224 0.027
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.026
phosphorylation GO:0016310 69 0.025
positive regulation of multicellular organismal process GO:0051240 52 0.025
phosphate containing compound metabolic process GO:0006796 108 0.025
regulation of organelle organization GO:0033043 29 0.024
regulation of localization GO:0032879 104 0.024
Zebrafish
cellular response to chemical stimulus GO:0070887 157 0.024
cellular protein metabolic process GO:0044267 129 0.024
endothelium development GO:0003158 25 0.024
Zebrafish
cell death GO:0008219 121 0.024
cellular protein modification process GO:0006464 100 0.023
fatty acid biosynthetic process GO:0006633 4 0.023
determination of dorsal ventral asymmetry GO:0048262 34 0.023
regulation of cell differentiation GO:0045595 142 0.023
hindbrain development GO:0030902 91 0.023
negative regulation of endopeptidase activity GO:0010951 10 0.022
response to carbohydrate GO:0009743 3 0.022
response to chemical GO:0042221 320 0.022
segmentation GO:0035282 97 0.022
regulation of calcium ion transport GO:0051924 2 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
notochord development GO:0030903 54 0.022
positive regulation of developmental process GO:0051094 50 0.022
regulation of anatomical structure morphogenesis GO:0022603 130 0.022
lipid biosynthetic process GO:0008610 22 0.022
gland development GO:0048732 143 0.021
response to organic cyclic compound GO:0014070 51 0.021
eye development GO:0001654 277 0.021
sensory organ morphogenesis GO:0090596 200 0.020
mesoderm development GO:0007498 88 0.020
brain development GO:0007420 293 0.020
autophagy GO:0006914 4 0.020
immune response GO:0006955 28 0.020
sexual reproduction GO:0019953 36 0.020
leukocyte proliferation GO:0070661 1 0.020
regulation of reactive oxygen species metabolic process GO:2000377 2 0.020
protein modification process GO:0036211 100 0.020
mitochondrion organization GO:0007005 4 0.019
positive regulation of cellular process GO:0048522 201 0.019
spindle assembly involved in mitosis GO:0090307 1 0.019
regulation of tube size GO:0035150 2 0.019
intracellular signal transduction GO:0035556 85 0.019
proepicardium development GO:0003342 4 0.019
positive regulation of phosphorus metabolic process GO:0010562 21 0.019
alcohol metabolic process GO:0006066 11 0.019
lateral inhibition GO:0046331 1 0.019
cell projection morphogenesis GO:0048858 244 0.019
long chain fatty acid metabolic process GO:0001676 1 0.019
cellular component morphogenesis GO:0032989 336 0.019
cell projection organization GO:0030030 284 0.019
heart jogging GO:0003146 40 0.019
nucleic acid templated transcription GO:0097659 181 0.019
negative regulation of cellular biosynthetic process GO:0031327 55 0.018
positive regulation of catalytic activity GO:0043085 25 0.018
erythrocyte homeostasis GO:0034101 55 0.018
negative regulation of apoptotic process GO:0043066 55 0.018
stem cell development GO:0048864 82 0.018
regulation of cell death GO:0010941 103 0.018
cellular response to nutrient levels GO:0031669 2 0.018
response to ketone GO:1901654 1 0.018
sodium ion transport GO:0006814 24 0.018
Zebrafish
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.017
atrioventricular valve formation GO:0003190 3 0.017
lymphocyte proliferation GO:0046651 1 0.017
exocytosis GO:0006887 1 0.017
nitric oxide metabolic process GO:0046209 2 0.017
tissue regeneration GO:0042246 74 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
female sex differentiation GO:0046660 4 0.017
developmental growth GO:0048589 166 0.017
dorsal ventral pattern formation GO:0009953 125 0.016
very long chain fatty acid metabolic process GO:0000038 4 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
septum transversum development GO:0003343 4 0.016
macromolecular complex subunit organization GO:0043933 74 0.016
oxoacid metabolic process GO:0043436 31 0.016
negative regulation of developmental process GO:0051093 65 0.016
negative regulation of cellular metabolic process GO:0031324 77 0.016
blood vessel development GO:0001568 246 0.016
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.016
liver development GO:0001889 96 0.016
negative regulation of molecular function GO:0044092 23 0.016
microtubule polymerization GO:0046785 2 0.015
positive regulation of exocytosis GO:0045921 1 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
heart morphogenesis GO:0003007 156 0.015
ameboidal type cell migration GO:0001667 143 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
positive regulation of cell division GO:0051781 2 0.015
growth GO:0040007 174 0.015
response to inorganic substance GO:0010035 38 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
nuclear import GO:0051170 3 0.015
organic hydroxy compound metabolic process GO:1901615 16 0.015
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 1 0.015
blood vessel morphogenesis GO:0048514 216 0.015
hormone metabolic process GO:0042445 19 0.015
muscle structure development GO:0061061 196 0.015
apoptotic process GO:0006915 116 0.015
regulation of cell activation GO:0050865 1 0.015
cellular response to antibiotic GO:0071236 1 0.015
establishment of endothelial barrier GO:0061028 3 0.014
Zebrafish
programmed cell death GO:0012501 119 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
cellular component biogenesis GO:0044085 178 0.014
cellular component assembly GO:0022607 170 0.014
chemical homeostasis GO:0048878 49 0.014
stem cell proliferation GO:0072089 4 0.014
regulation of transport GO:0051049 45 0.014
Zebrafish
localization of cell GO:0051674 244 0.014
response to monosaccharide GO:0034284 3 0.014
regulation of protein metabolic process GO:0051246 56 0.014
positive regulation of biological process GO:0048518 253 0.014
regulation of blood vessel size GO:0050880 2 0.014
striated muscle cell differentiation GO:0051146 129 0.014
lateral line development GO:0048882 66 0.014
Zebrafish
proteasomal protein catabolic process GO:0010498 2 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.013
positive regulation of muscle organ development GO:0048636 1 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.013
macromolecule modification GO:0043412 111 0.013
negative regulation of programmed cell death GO:0043069 58 0.013
neuron differentiation GO:0030182 353 0.013
blood circulation GO:0008015 87 0.013
protein phosphorylation GO:0006468 47 0.013
erythrocyte development GO:0048821 24 0.013
single fertilization GO:0007338 3 0.013
regulation of immune system process GO:0002682 34 0.013
cellular protein catabolic process GO:0044257 4 0.013
response to uv GO:0009411 3 0.013
negative regulation of metabolic process GO:0009892 86 0.013
cellular response to organic substance GO:0071310 105 0.013
reactive oxygen species biosynthetic process GO:1903409 1 0.013
female gonad development GO:0008585 4 0.012
germ cell migration GO:0008354 8 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.012
b cell activation GO:0042113 2 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.012
cell migration involved in gastrulation GO:0042074 79 0.012
protein import GO:0017038 3 0.012
response to vitamin b3 GO:0033552 2 0.012
regulation of multicellular organism growth GO:0040014 4 0.012
positive regulation of transcription dna templated GO:0045893 57 0.012
cardiac ventricle formation GO:0003211 1 0.012
cardiac atrium development GO:0003230 4 0.012
regulation of gtpase activity GO:0043087 2 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
response to hexose GO:0009746 3 0.012
single organism organelle organization GO:1902589 199 0.012
organic hydroxy compound biosynthetic process GO:1901617 6 0.012
embryonic digestive tract development GO:0048566 4 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
g protein coupled receptor signaling pathway GO:0007186 74 0.012
epiboly GO:0090504 41 0.011
Zebrafish
semicircular canal development GO:0060872 24 0.011
fin regeneration GO:0031101 51 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
endodermal cell fate determination GO:0007493 2 0.011
regulation of cellular component organization GO:0051128 86 0.011
heart process GO:0003015 71 0.011
establishment of blood brain barrier GO:0060856 2 0.011
positive regulation of peptidase activity GO:0010952 10 0.011
positive regulation of cytokine production GO:0001819 2 0.011
positive regulation of phosphate metabolic process GO:0045937 21 0.011
negative regulation of multi organism process GO:0043901 3 0.011
regulation of blood circulation GO:1903522 32 0.011
cofactor biosynthetic process GO:0051188 10 0.011
negative regulation of biosynthetic process GO:0009890 55 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.011
response to oxygen containing compound GO:1901700 55 0.011
protein processing GO:0016485 12 0.011
peripheral nervous system development GO:0007422 55 0.011
response to endogenous stimulus GO:0009719 83 0.011
response to corticosteroid GO:0031960 1 0.011
regulation of cell cycle GO:0051726 52 0.011
cell cell signaling GO:0007267 52 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
cellular homeostasis GO:0019725 26 0.011
embryonic pattern specification GO:0009880 44 0.011
multicellular organism reproduction GO:0032504 35 0.010
cardiac chamber formation GO:0003207 4 0.010
skeletal system development GO:0001501 181 0.010
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.010
positive regulation of nucleic acid templated transcription GO:1903508 57 0.010
meiotic cell cycle process GO:1903046 3 0.010
negative regulation of myeloid cell differentiation GO:0045638 1 0.010
endodermal cell fate specification GO:0001714 17 0.010
response to nutrient GO:0007584 3 0.010
regulation of response to stress GO:0080134 36 0.010
mononuclear cell proliferation GO:0032943 1 0.010
translational initiation GO:0006413 3 0.010

cldng disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
reproductive system disease DOID:15 0 0.034
disease of metabolism DOID:0014667 0 0.025
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
sensory system disease DOID:0050155 0 0.011
nervous system disease DOID:863 0 0.011