Danio rerio

0 known processes

clic4

chloride intracellular channel 4

(Aliases: wu:fb33c05,cb142,wu:fc30h10)

clic4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of biological process GO:0048519 304 0.266
Human
signal transduction GO:0007165 455 0.250
embryo development ending in birth or egg hatching GO:0009792 271 0.246
cellular component movement GO:0006928 335 0.222
Human
regulation of stem cell differentiation GO:2000736 4 0.217
larval development GO:0002164 2 0.210
cell motility GO:0048870 244 0.173
Human
aging GO:0007568 2 0.170
regulation of response to stimulus GO:0048583 269 0.161
embryonic organ development GO:0048568 381 0.158
negative regulation of cellular process GO:0048523 283 0.151
Human
positive regulation of cell cycle GO:0045787 3 0.147
establishment of localization GO:0051234 244 0.132
vasculature development GO:0001944 278 0.132
Mouse
blood vessel development GO:0001568 246 0.132
Mouse
regulation of multicellular organismal process GO:0051239 277 0.128
detection of temperature stimulus involved in sensory perception GO:0050961 0 0.127
positive regulation of transport GO:0051050 2 0.125
regulation of cell projection assembly GO:0060491 4 0.121
endothelium development GO:0003158 25 0.117
Mouse
endothelial cell fate commitment GO:0060839 3 0.116
somite development GO:0061053 96 0.110
protein targeting to nucleus GO:0044744 3 0.106
cell morphogenesis GO:0000902 289 0.105
Mouse
regulation of purine nucleotide catabolic process GO:0033121 2 0.102
single organismal cell cell adhesion GO:0016337 29 0.101
regulation of intracellular protein transport GO:0033157 3 0.098
regulation of reproductive process GO:2000241 4 0.095
localization of cell GO:0051674 244 0.094
Human
nephron epithelium morphogenesis GO:0072088 1 0.093
response to chemical GO:0042221 320 0.092
Human
angiogenesis GO:0001525 158 0.091
Mouse
blood vessel morphogenesis GO:0048514 216 0.083
Mouse
regulation of protein binding GO:0043393 3 0.081
regulation of cytoplasmic transport GO:1903649 4 0.081
negative regulation of stem cell differentiation GO:2000737 2 0.079
regulation of cellular component movement GO:0051270 55 0.075
Human
regulation of collateral sprouting in absence of injury GO:0048696 4 0.074
regulation of axonogenesis GO:0050770 32 0.073
response to external stimulus GO:0009605 264 0.072
locomotion GO:0040011 313 0.070
Human
positive regulation of striated muscle tissue development GO:0045844 1 0.061
response to lipid GO:0033993 60 0.061
neuron development GO:0048666 262 0.059
protein import into nucleus GO:0006606 3 0.058
single organism localization GO:1902578 225 0.057
maintenance of location GO:0051235 4 0.057
positive regulation of neural precursor cell proliferation GO:2000179 1 0.056
lymph vessel development GO:0001945 27 0.056
multicellular organism growth GO:0035264 4 0.056
Mouse
lipid storage GO:0019915 1 0.056
endothelial cell differentiation GO:0045446 20 0.055
Mouse
skeletal system development GO:0001501 181 0.054
carboxylic acid metabolic process GO:0019752 22 0.054
stem cell maintenance GO:0019827 4 0.053
somitogenesis GO:0001756 87 0.052
cell morphogenesis involved in differentiation GO:0000904 195 0.052
Mouse
regulation of developmental process GO:0050793 247 0.052
response to nutrient GO:0007584 3 0.051
dna biosynthetic process GO:0071897 3 0.051
ventricular system development GO:0021591 12 0.051
cell migration GO:0016477 237 0.051
Human
pyruvate metabolic process GO:0006090 1 0.050
regulation of cell projection organization GO:0031344 44 0.050
carbohydrate derivative biosynthetic process GO:1901137 43 0.048
neuron projection morphogenesis GO:0048812 161 0.048
regionalization GO:0003002 274 0.048
cellular response to reactive oxygen species GO:0034614 2 0.047
regulation of cellular response to oxidative stress GO:1900407 2 0.047
embryonic cranial skeleton morphogenesis GO:0048701 90 0.047
actin filament based movement GO:0030048 1 0.047
regulation of catenin import into nucleus GO:0035412 2 0.046
regulation of signal transduction GO:0009966 225 0.046
rna localization GO:0006403 4 0.045
actin mediated cell contraction GO:0070252 1 0.045
ameboidal type cell migration GO:0001667 143 0.045
nephron tubule morphogenesis GO:0072078 1 0.044
cellular component disassembly GO:0022411 1 0.044
segmentation GO:0035282 97 0.043
head development GO:0060322 303 0.043
positive regulation of muscle cell differentiation GO:0051149 1 0.042
regulation of cellular metabolic process GO:0031323 320 0.042
regulation of protein import into nucleus GO:0042306 2 0.042
protein import GO:0017038 3 0.042
rna metabolic process GO:0016070 219 0.041
cellular component biogenesis GO:0044085 178 0.040
small molecule metabolic process GO:0044281 77 0.039
positive regulation of catabolic process GO:0009896 4 0.039
regulation of primary metabolic process GO:0080090 311 0.039
microtubule organizing center organization GO:0031023 1 0.039
oxoacid metabolic process GO:0043436 31 0.039
organic acid metabolic process GO:0006082 31 0.038
meiotic nuclear division GO:0007126 4 0.038
detection of temperature stimulus GO:0016048 0 0.038
primary neural tube formation GO:0014020 1 0.038
cellular component morphogenesis GO:0032989 336 0.038
Mouse
3 utr mediated mrna stabilization GO:0070935 3 0.038
response to mercury ion GO:0046689 1 0.038
transport GO:0006810 220 0.038
protein localization to nucleus GO:0034504 3 0.037
rna stabilization GO:0043489 4 0.037
regulation of protein localization to nucleus GO:1900180 2 0.037
response to organic cyclic compound GO:0014070 51 0.036
regulation of protein targeting GO:1903533 2 0.036
generation of neurons GO:0048699 385 0.035
muscle cell differentiation GO:0042692 139 0.035
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.035
response to inorganic substance GO:0010035 38 0.035
Human
positive regulation of signaling GO:0023056 56 0.034
protein o linked glycosylation GO:0006493 4 0.034
positive regulation of dna metabolic process GO:0051054 1 0.034
epithelial cell differentiation GO:0030855 116 0.034
Human Mouse
cellular protein metabolic process GO:0044267 129 0.033
regulation of nucleoside metabolic process GO:0009118 2 0.033
single organism metabolic process GO:0044710 217 0.033
nuclear import GO:0051170 3 0.032
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.032
positive regulation of ras protein signal transduction GO:0046579 1 0.032
rhombomere formation GO:0021594 12 0.032
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.032
oocyte development GO:0048599 14 0.032
regulation of nucleotide catabolic process GO:0030811 2 0.032
nucleocytoplasmic transport GO:0006913 4 0.032
germ line stem cell maintenance GO:0030718 2 0.032
embryonic heart tube morphogenesis GO:0003143 108 0.031
spermatid development GO:0007286 2 0.031
response to organic substance GO:0010033 153 0.031
single organism nuclear import GO:1902593 3 0.031
muscle organ development GO:0007517 101 0.031
regulation of signaling GO:0023051 235 0.030
negative regulation of mitosis GO:0045839 3 0.030
sexual reproduction GO:0019953 36 0.030
Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.030
regulation of apoptotic process GO:0042981 98 0.029
peptidyl lysine acetylation GO:0018394 2 0.029
renal tubule morphogenesis GO:0061333 1 0.029
positive regulation of gtp catabolic process GO:0033126 1 0.029
regulation of embryonic development GO:0045995 47 0.029
embryonic pattern specification GO:0009880 44 0.029
negative regulation of cytoplasmic transport GO:1903650 2 0.029
regulation of nitrogen compound metabolic process GO:0051171 251 0.028
single organism transport GO:0044765 206 0.028
cellular ketone metabolic process GO:0042180 11 0.028
negative regulation of cell migration GO:0030336 17 0.028
Human
regulation of binding GO:0051098 3 0.028
regulation of cell activation GO:0050865 1 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.028
cellular protein modification process GO:0006464 100 0.028
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.027
anterior posterior pattern specification GO:0009952 152 0.027
protein acylation GO:0043543 3 0.027
cellular amino acid metabolic process GO:0006520 7 0.027
regulation of intracellular signal transduction GO:1902531 57 0.027
sex determination GO:0007530 1 0.026
regulation of programmed cell death GO:0043067 101 0.026
compound eye development GO:0048749 2 0.026
regulation of multicellular organism growth GO:0040014 4 0.026
sprouting angiogenesis GO:0002040 53 0.026
determination of bilateral symmetry GO:0009855 204 0.026
regulation of establishment of protein localization GO:0070201 4 0.026
single organism cell adhesion GO:0098602 29 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.026
heart development GO:0007507 313 0.026
amine metabolic process GO:0009308 2 0.026
neutrophil chemotaxis GO:0030593 10 0.026
tube morphogenesis GO:0035239 349 0.026
Mouse
regulation of mitotic cell cycle embryonic GO:0009794 2 0.025
small gtpase mediated signal transduction GO:0007264 8 0.025
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
establishment of cell polarity GO:0030010 18 0.025
regulation of epithelial to mesenchymal transition GO:0010717 3 0.025
intracellular signal transduction GO:0035556 85 0.025
response to acid chemical GO:0001101 17 0.024
lateral inhibition GO:0046331 1 0.024
regulation of localization GO:0032879 104 0.024
Human
response to abiotic stimulus GO:0009628 122 0.024
gtp metabolic process GO:0046039 4 0.024
organelle organization GO:0006996 227 0.024
muscle tissue development GO:0060537 110 0.024
ras protein signal transduction GO:0007265 7 0.024
positive regulation of nucleoside metabolic process GO:0045979 1 0.024
determination of left right symmetry GO:0007368 179 0.023
embryonic heart tube development GO:0035050 133 0.023
specification of axis polarity GO:0065001 4 0.023
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.023
cell surface receptor signaling pathway GO:0007166 325 0.023
mrna stabilization GO:0048255 4 0.023
regulation of locomotion GO:0040012 55 0.023
Human
digestive system development GO:0055123 289 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
negative regulation of cellular component movement GO:0051271 18 0.023
Human
negative regulation of blood vessel endothelial cell migration GO:0043537 1 0.023
regulation of gtp catabolic process GO:0033124 2 0.023
epithelial cell morphogenesis GO:0003382 2 0.023
Mouse
response to carbohydrate GO:0009743 3 0.023
regulation of biological quality GO:0065008 263 0.023
Mouse
positive regulation of cellular amine metabolic process GO:0033240 0 0.023
regulation of jun kinase activity GO:0043506 3 0.022
lymphangiogenesis GO:0001946 25 0.022
negative regulation of myeloid cell differentiation GO:0045638 1 0.022
secondary metabolic process GO:0019748 3 0.022
determination of heart left right asymmetry GO:0061371 117 0.022
apoptotic process GO:0006915 116 0.022
nuclear transport GO:0051169 4 0.022
neuron projection development GO:0031175 180 0.022
protein modification process GO:0036211 100 0.022
cell projection morphogenesis GO:0048858 244 0.022
multicellular organismal signaling GO:0035637 22 0.022
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
regulation of cell communication GO:0010646 232 0.022
establishment of protein localization to organelle GO:0072594 4 0.022
response to drug GO:0042493 3 0.021
regulation of metabolic process GO:0019222 359 0.021
regulation of protein transport GO:0051223 3 0.021
negative regulation of cell motility GO:2000146 17 0.021
Human
negative regulation of apoptotic process GO:0043066 55 0.021
epithelial cell development GO:0002064 42 0.021
Mouse
negative regulation of signal transduction GO:0009968 94 0.021
kidney development GO:0001822 92 0.021
regulation of metal ion transport GO:0010959 4 0.021
negative regulation of cellular metabolic process GO:0031324 77 0.020
phagocytosis GO:0006909 3 0.020
negative regulation of cell communication GO:0010648 96 0.020
digestive tract morphogenesis GO:0048546 231 0.020
regulation of mrna processing GO:0050684 3 0.020
heart looping GO:0001947 94 0.020
glial cell migration GO:0008347 3 0.020
regulation of cell size GO:0008361 29 0.020
regulation of anatomical structure morphogenesis GO:0022603 130 0.020
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.020
nephron tubule development GO:0072080 4 0.020
mitotic cell cycle embryonic GO:0045448 2 0.020
positive regulation of reproductive process GO:2000243 2 0.020
embryonic organ morphogenesis GO:0048562 274 0.020
protein phosphorylation GO:0006468 47 0.020
negative regulation of nuclear division GO:0051784 3 0.020
positive regulation of cell communication GO:0010647 56 0.020
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.020
centrosome organization GO:0051297 1 0.020
negative regulation of neutrophil migration GO:1902623 3 0.020
cellular amine metabolic process GO:0044106 2 0.020
muscle cell development GO:0055001 115 0.020
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.019
cellular response to prostaglandin stimulus GO:0071379 3 0.019
positive regulation of cellular process GO:0048522 201 0.019
chordate embryonic development GO:0043009 271 0.019
regulation of meiotic cell cycle GO:0051445 1 0.019
embryonic skeletal joint morphogenesis GO:0060272 3 0.019
renal tubule development GO:0061326 5 0.019
central nervous system development GO:0007417 387 0.019
axis specification GO:0009798 43 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.019
reproductive process GO:0022414 40 0.019
Mouse
lens fiber cell development GO:0070307 3 0.019
regulation of neural precursor cell proliferation GO:2000177 3 0.019
cell proliferation in forebrain GO:0021846 3 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
negative regulation of neutrophil chemotaxis GO:0090024 3 0.019
phosphorus metabolic process GO:0006793 109 0.019
alternative mrna splicing via spliceosome GO:0000380 1 0.019
protein acetylation GO:0006473 2 0.019
proximal distal pattern formation GO:0009954 1 0.019
cell cycle GO:0007049 93 0.019
regulation of cardiac muscle tissue development GO:0055024 1 0.018
mesenchymal cell development GO:0014031 78 0.018
rhombomere morphogenesis GO:0021593 17 0.018
axonogenesis GO:0007409 152 0.018
positive regulation of metabolic process GO:0009893 108 0.018
immune system development GO:0002520 191 0.018
negative regulation of axon extension GO:0030517 7 0.018
establishment of endothelial barrier GO:0061028 3 0.018
single organism reproductive process GO:0044702 40 0.018
Mouse
mesodermal cell migration GO:0008078 12 0.018
positive regulation of biological process GO:0048518 253 0.018
cell projection organization GO:0030030 284 0.018
negative regulation of collateral sprouting GO:0048671 2 0.018
protein metabolic process GO:0019538 183 0.018
regulation of rho protein signal transduction GO:0035023 2 0.017
biosynthetic process GO:0009058 294 0.017
neuroblast proliferation GO:0007405 2 0.017
regulation of sodium ion transport GO:0002028 2 0.017
cell cycle g1 s phase transition GO:0044843 1 0.017
regulation of cell motility GO:2000145 46 0.017
Human
response to endogenous stimulus GO:0009719 83 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
gtp catabolic process GO:0006184 2 0.017
regulation of catalytic activity GO:0050790 55 0.017
specification of organ identity GO:0010092 2 0.017
neuron differentiation GO:0030182 353 0.017
spermatid differentiation GO:0048515 2 0.017
detection of stimulus involved in sensory perception GO:0050906 21 0.017
macromolecule modification GO:0043412 111 0.017
regulation of cell cycle process GO:0010564 20 0.017
cell death in response to oxidative stress GO:0036473 2 0.017
negative regulation of gene expression GO:0010629 65 0.017
defense response to fungus GO:0050832 2 0.017
regulation of neurogenesis GO:0050767 87 0.016
single organism cellular localization GO:1902580 46 0.016
cell cycle arrest GO:0007050 1 0.016
nitrogen compound metabolic process GO:0006807 319 0.016
nephron morphogenesis GO:0072028 2 0.016
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
internal protein amino acid acetylation GO:0006475 2 0.016
male meiosis GO:0007140 2 0.016
positive regulation of chromosome organization GO:2001252 1 0.016
hypochord development GO:0055016 3 0.016
negative regulation of rna metabolic process GO:0051253 48 0.016
midbrain hindbrain boundary development GO:0030917 23 0.016
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.016
regulation of myelination GO:0031641 1 0.016
liver development GO:0001889 96 0.016
positive regulation of macromolecule metabolic process GO:0010604 93 0.016
canonical wnt signaling pathway involved in heart development GO:0061316 1 0.016
centrosome cycle GO:0007098 1 0.016
optic placode formation involved in camera type eye formation GO:0046619 3 0.016
macromolecular complex disassembly GO:0032984 1 0.016
regulation of establishment of planar polarity GO:0090175 4 0.016
striated muscle cell differentiation GO:0051146 129 0.016
catenin import into nucleus GO:0035411 2 0.016
cellular aromatic compound metabolic process GO:0006725 295 0.016
transcription from rna polymerase iii promoter GO:0006383 1 0.015
response to oxygen containing compound GO:1901700 55 0.015
cellular macromolecule metabolic process GO:0044260 391 0.015
negative regulation of dna metabolic process GO:0051053 4 0.015
regulation of cell migration GO:0030334 40 0.015
Human
regulation of dna replication GO:0006275 3 0.015
protein complex disassembly GO:0043241 1 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
long chain fatty acid metabolic process GO:0001676 1 0.015
lymphatic endothelial cell differentiation GO:0060836 1 0.015
response to uv GO:0009411 3 0.015
mitochondrion organization GO:0007005 4 0.015
mechanosensory behavior GO:0007638 2 0.015
negative regulation of protein transport GO:0051224 3 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
Human
endocytosis GO:0006897 16 0.015
regulation of skeletal muscle tissue development GO:0048641 4 0.015
regulation of ras gtpase activity GO:0032318 2 0.015
negative regulation of metabolic process GO:0009892 86 0.015
lamellipodium organization GO:0097581 1 0.015
somatic stem cell maintenance GO:0035019 1 0.015
neural crest cell differentiation GO:0014033 72 0.015
regulation of cell cell adhesion GO:0022407 13 0.015
entrainment of circadian clock by photoperiod GO:0043153 1 0.015
negative regulation of intracellular protein transport GO:0090317 3 0.015
vesicle mediated transport GO:0016192 22 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
spindle localization GO:0051653 12 0.015
cellular response to nutrient levels GO:0031669 2 0.015
cartilage development GO:0051216 96 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
bone remodeling GO:0046849 2 0.014
single fertilization GO:0007338 3 0.014
lipid metabolic process GO:0006629 52 0.014
optic placode formation GO:0001743 4 0.014
gall bladder development GO:0061010 1 0.014
nucleic acid metabolic process GO:0090304 244 0.014
response to hydrogen peroxide GO:0042542 3 0.014
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.014
negative regulation of kinase activity GO:0033673 4 0.014
positive regulation of muscle tissue development GO:1901863 1 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
oogenesis GO:0048477 14 0.014
rhombomere boundary formation GO:0021654 10 0.014
regulation of fatty acid metabolic process GO:0019217 1 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.014
canonical wnt signaling pathway GO:0060070 48 0.014
lymph vessel morphogenesis GO:0036303 25 0.014
response to stress GO:0006950 263 0.014
female gonad development GO:0008585 4 0.014
peptide transport GO:0015833 1 0.014
maternal determination of anterior posterior axis embryo GO:0008358 4 0.014
anterior head development GO:0097065 2 0.014
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.014
response to other organism GO:0051707 97 0.014
adherens junction organization GO:0034332 4 0.014
hepatocyte proliferation GO:0072574 2 0.014
negative regulation of cell death GO:0060548 60 0.014
negative regulation of dna replication GO:0008156 2 0.014
positive regulation of striated muscle cell differentiation GO:0051155 1 0.014
gamete generation GO:0007276 33 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
Mouse
cell part morphogenesis GO:0032990 246 0.014
regulation of receptor mediated endocytosis GO:0048259 4 0.014
lens fiber cell morphogenesis GO:0070309 3 0.014
sister chromatid cohesion GO:0007062 2 0.013
regulation of gtpase activity GO:0043087 2 0.013
ion transport GO:0006811 114 0.013
negative regulation of leukocyte chemotaxis GO:0002689 3 0.013
heterocycle metabolic process GO:0046483 290 0.013
cellular response to fatty acid GO:0071398 3 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
cardiac atrium morphogenesis GO:0003209 2 0.013
negative regulation of developmental process GO:0051093 65 0.013
regulation of response to oxidative stress GO:1902882 2 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.013
gastrulation GO:0007369 208 0.013
muscle structure development GO:0061061 196 0.013
cellular response to estradiol stimulus GO:0071392 1 0.013
blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 4 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
organelle assembly GO:0070925 110 0.013
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 1 0.013
cognition GO:0050890 1 0.013
cell adhesion GO:0007155 40 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
mesoderm development GO:0007498 88 0.013
formation of primary germ layer GO:0001704 62 0.013
regulation of neuron differentiation GO:0045664 56 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.013
cell aging GO:0007569 2 0.013
regulation of dna templated transcription in response to stress GO:0043620 0 0.013
macromolecule glycosylation GO:0043413 9 0.013
negative regulation of axon regeneration GO:0048681 4 0.013
negative regulation of protein kinase b signaling GO:0051898 2 0.012
programmed cell death GO:0012501 119 0.012
somite specification GO:0001757 12 0.012
tissue remodeling GO:0048771 4 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
skeletal muscle organ development GO:0060538 78 0.012
death GO:0016265 121 0.012
odontogenesis of dentin containing tooth GO:0042475 1 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.012
regulation of calcium ion dependent exocytosis GO:0017158 1 0.012
negative regulation of activin receptor signaling pathway GO:0032926 5 0.012
developmental process involved in reproduction GO:0003006 27 0.012
intracellular transport GO:0046907 32 0.012
system process GO:0003008 185 0.012
positive regulation of ras gtpase activity GO:0032320 1 0.012
female sex differentiation GO:0046660 4 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
cellular response to organic cyclic compound GO:0071407 38 0.012
cell substrate junction assembly GO:0007044 2 0.012
ear development GO:0043583 127 0.012
multicellular organism reproduction GO:0032504 35 0.012
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.012
multicellular organismal response to stress GO:0033555 2 0.012
phagocytosis engulfment GO:0006911 1 0.012
response to hypoxia GO:0001666 25 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
protein stabilization GO:0050821 2 0.012
cellular amino acid biosynthetic process GO:0008652 2 0.012
response to temperature stimulus GO:0009266 15 0.012
negative regulation of signaling GO:0023057 96 0.012
regulation of gene expression GO:0010468 265 0.012
cell cell recognition GO:0009988 1 0.012
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.012
endothelial cell development GO:0001885 12 0.012
Mouse
regulation of stem cell proliferation GO:0072091 2 0.012
positive regulation of mesoderm development GO:2000382 1 0.012
organic substance biosynthetic process GO:1901576 289 0.012
multi organism process GO:0051704 134 0.011
Mouse
pyrimidine containing compound metabolic process GO:0072527 3 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
protein depolymerization GO:0051261 1 0.011
response to estrogen GO:0043627 27 0.011
protein localization to plasma membrane GO:0072659 1 0.011
stem cell development GO:0048864 82 0.011
cellular response to estrogen stimulus GO:0071391 24 0.011
endocardial cushion development GO:0003197 6 0.011
regulation of anatomical structure size GO:0090066 33 0.011
cell cycle g2 m phase transition GO:0044839 4 0.011
cardiac atrium development GO:0003230 4 0.011
positive regulation of notch signaling pathway GO:0045747 3 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
cardiac cell fate commitment GO:0060911 1 0.011
patterning of lymph vessels GO:0060854 1 0.011
skeletal system morphogenesis GO:0048705 102 0.011
heart field specification GO:0003128 1 0.011
neurological system process GO:0050877 62 0.011
regulation of cardiac muscle contraction GO:0055117 2 0.011
establishment of spindle localization GO:0051293 12 0.011
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
regulation of mitotic cell cycle GO:0007346 25 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
regulation of oxidative stress induced cell death GO:1903201 2 0.011
neutrophil migration GO:1990266 10 0.011
lamellipodium assembly GO:0030032 1 0.011
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.011
pole plasm assembly GO:0007315 4 0.011
positive regulation of translation GO:0045727 1 0.011
radial glial cell differentiation GO:0060019 2 0.011
regulation of extent of cell growth GO:0061387 29 0.011

clic4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.024
bone disease DOID:0080001 0 0.024
disease of anatomical entity DOID:7 0 0.024
musculoskeletal system disease DOID:17 0 0.024
connective tissue disease DOID:65 0 0.024
nervous system disease DOID:863 0 0.013
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012