Danio rerio

59 known processes

cmlc1

cardiac myosin light chain-1

(Aliases: zgc:103441)

cmlc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of muscle contraction GO:0006937 3 0.914
myofibril assembly GO:0030239 48 0.745
muscle structure development GO:0061061 196 0.745
heart development GO:0007507 313 0.637
actin filament based movement GO:0030048 1 0.579
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.576
muscle contraction GO:0006936 18 0.575
Rat
cardiac chamber formation GO:0003207 4 0.543
negative regulation of blood circulation GO:1903523 2 0.537
striated muscle tissue development GO:0014706 110 0.531
actomyosin structure organization GO:0031032 53 0.460
regulation of mechanoreceptor differentiation GO:0045631 1 0.431
tube morphogenesis GO:0035239 349 0.429
embryonic heart tube development GO:0035050 133 0.398
ventricular cardiac muscle tissue development GO:0003229 3 0.393
fluid transport GO:0042044 17 0.380
striated muscle cell development GO:0055002 108 0.379
inorganic cation transmembrane transport GO:0098662 50 0.371
cellular response to steroid hormone stimulus GO:0071383 31 0.362
negative regulation of heart contraction GO:0045822 2 0.348
actin filament based process GO:0030029 64 0.348
positive regulation of heart contraction GO:0045823 2 0.335
cardiac muscle cell development GO:0055013 20 0.320
positive regulation of blood circulation GO:1903524 2 0.300
heart morphogenesis GO:0003007 156 0.299
embryonic heart tube morphogenesis GO:0003143 108 0.292
cellular component biogenesis GO:0044085 178 0.289
epithelial tube morphogenesis GO:0060562 148 0.287
regulation of system process GO:0044057 40 0.277
specification of symmetry GO:0009799 204 0.276
cation homeostasis GO:0055080 33 0.271
atrial cardiac myofibril assembly GO:0055004 2 0.266
larval development GO:0002164 2 0.260
transmembrane transport GO:0055085 120 0.258
cardiocyte differentiation GO:0035051 44 0.250
cation transmembrane transport GO:0098655 65 0.248
cardiac muscle cell contraction GO:0086003 1 0.242
adult behavior GO:0030534 2 0.238
organelle assembly GO:0070925 110 0.230
ribonucleoside monophosphate catabolic process GO:0009158 4 0.229
metal ion homeostasis GO:0055065 26 0.227
actin mediated cell contraction GO:0070252 1 0.222
inorganic ion transmembrane transport GO:0098660 57 0.203
cardiac muscle tissue development GO:0048738 48 0.203
ion transmembrane transport GO:0034220 91 0.201
heart jogging GO:0003146 40 0.198
ventricular cardiac muscle cell development GO:0055015 5 0.196
striated muscle cell differentiation GO:0051146 129 0.189
purine nucleoside monophosphate catabolic process GO:0009128 4 0.188
cell migration involved in heart development GO:0060973 22 0.183
atrial cardiac muscle cell development GO:0055014 4 0.178
regulation of multicellular organismal process GO:0051239 277 0.174
regulation of heart contraction GO:0008016 32 0.173
muscle organ development GO:0007517 101 0.170
Rat
heart looping GO:0001947 94 0.169
embryo development ending in birth or egg hatching GO:0009792 271 0.165
Worm
calcium ion import GO:0070509 4 0.161
nucleoside monophosphate catabolic process GO:0009125 4 0.158
atp catabolic process GO:0006200 4 0.154
regulation of cardiac muscle cell contraction GO:0086004 1 0.150
heart contraction GO:0060047 71 0.146
cardiac muscle cell differentiation GO:0055007 30 0.146
cardiac ventricle formation GO:0003211 1 0.141
cellular component assembly involved in morphogenesis GO:0010927 107 0.127
muscle cell differentiation GO:0042692 139 0.126
cardiac muscle tissue morphogenesis GO:0055008 7 0.126
cellular response to lipid GO:0071396 39 0.125
divalent inorganic cation homeostasis GO:0072507 22 0.118
sodium ion import GO:0097369 3 0.118
heart process GO:0003015 71 0.109
cardiac chamber morphogenesis GO:0003206 12 0.108
system process GO:0003008 185 0.108
muscle system process GO:0003012 20 0.108
Rat
morphogenesis of an epithelium GO:0002009 333 0.108
regulation of blood circulation GO:1903522 32 0.105
signal transduction GO:0007165 455 0.104
muscle tissue development GO:0060537 110 0.102
cardiac atrium morphogenesis GO:0003209 2 0.100
endocardial cushion formation GO:0003272 2 0.097
determination of left right symmetry GO:0007368 179 0.096
regulation of heart morphogenesis GO:2000826 17 0.094
regulation of cardiac muscle contraction GO:0055117 2 0.093
determination of heart left right asymmetry GO:0061371 117 0.090
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.089
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.084
atrioventricular valve formation GO:0003190 3 0.084
cellular chemical homeostasis GO:0055082 17 0.084
positive regulation of striated muscle tissue development GO:0045844 1 0.083
regulation of purine nucleotide catabolic process GO:0033121 2 0.081
monovalent inorganic cation transport GO:0015672 42 0.080
response to lipid GO:0033993 60 0.080
regulation of biological quality GO:0065008 263 0.078
actin cytoskeleton organization GO:0030036 63 0.078
single organism localization GO:1902578 225 0.077
organelle organization GO:0006996 227 0.077
apical junction assembly GO:0043297 1 0.077
neuron fate determination GO:0048664 2 0.076
muscle cell development GO:0055001 115 0.075
aorta development GO:0035904 4 0.074
specification of organ axis polarity GO:0010084 2 0.074
embryonic organ morphogenesis GO:0048562 274 0.073
metal ion transport GO:0030001 58 0.071
lipid storage GO:0019915 1 0.071
maintenance of location GO:0051235 4 0.070
sodium ion transmembrane transport GO:0035725 21 0.070
endocardial cushion morphogenesis GO:0003203 3 0.069
determination of bilateral symmetry GO:0009855 204 0.068
regulation of striated muscle contraction GO:0006942 2 0.067
organic cyclic compound metabolic process GO:1901360 301 0.066
regulation of cell matrix adhesion GO:0001952 1 0.066
peptide metabolic process GO:0006518 1 0.065
regulation of response to stimulus GO:0048583 269 0.062
regulation of blood pressure GO:0008217 1 0.060
calcium ion transmembrane transport GO:0070588 13 0.059
cellular component morphogenesis GO:0032989 336 0.059
regulation of tube size GO:0035150 2 0.059
regulation of cardiac chamber formation GO:1901210 2 0.055
pharyngeal muscle development GO:0043282 4 0.055
cellular calcium ion homeostasis GO:0006874 13 0.054
cellular amide metabolic process GO:0043603 4 0.054
cellular cation homeostasis GO:0030003 17 0.053
calcium ion transport into cytosol GO:0060402 3 0.052
ion homeostasis GO:0050801 41 0.052
cell substrate adhesion GO:0031589 4 0.051
regulation of metabolic process GO:0019222 359 0.050
determination of left right asymmetry in nervous system GO:0035545 4 0.050
cellular sodium ion homeostasis GO:0006883 1 0.049
heart valve formation GO:0003188 4 0.049
blood circulation GO:0008015 87 0.049
calcium ion homeostasis GO:0055074 19 0.049
regulation of nucleoside metabolic process GO:0009118 2 0.048
ventricular cardiac muscle cell differentiation GO:0055012 6 0.047
muscle organ morphogenesis GO:0048644 8 0.047
atrial ventricular junction remodeling GO:0003294 2 0.045
pericardium development GO:0060039 1 0.045
aging GO:0007568 2 0.045
establishment of localization GO:0051234 244 0.045
regulation of nucleotide catabolic process GO:0030811 2 0.044
response to oxygen containing compound GO:1901700 55 0.044
regulation of cardiac chamber morphogenesis GO:1901219 2 0.044
nitrogen compound metabolic process GO:0006807 319 0.042
smooth muscle contraction GO:0006939 2 0.042
cardioblast migration to the midline involved in heart rudiment formation GO:0003319 5 0.041
heart field specification GO:0003128 1 0.041
cardiac ventricle morphogenesis GO:0003208 7 0.041
blood vessel endothelial cell differentiation GO:0060837 2 0.040
response to alkaloid GO:0043279 2 0.040
embryonic organ development GO:0048568 381 0.039
organonitrogen compound metabolic process GO:1901564 74 0.039
regulation of blood vessel size GO:0050880 2 0.039
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.038
regulation of ion transmembrane transporter activity GO:0032412 2 0.037
cellular response to hormone stimulus GO:0032870 39 0.037
cellular metal ion homeostasis GO:0006875 16 0.037
immune system process GO:0002376 241 0.036
single organism metabolic process GO:0044710 217 0.036
cation transport GO:0006812 81 0.036
establishment of protein localization to organelle GO:0072594 4 0.036
regulation of localization GO:0032879 104 0.036
catabolic process GO:0009056 32 0.035
sodium ion transport GO:0006814 24 0.034
regulation of cardiac muscle tissue development GO:0055024 1 0.034
organophosphate metabolic process GO:0019637 37 0.033
heterocycle metabolic process GO:0046483 290 0.033
hemopoiesis GO:0030097 183 0.032
regulation of anatomical structure morphogenesis GO:0022603 130 0.032
transport GO:0006810 220 0.032
protein import GO:0017038 3 0.032
response to hormone GO:0009725 48 0.031
sarcomere organization GO:0045214 26 0.031
embryonic skeletal joint development GO:0072498 3 0.031
regulation of sodium ion transport GO:0002028 2 0.030
nephron epithelium morphogenesis GO:0072088 1 0.030
glucocorticoid metabolic process GO:0008211 2 0.030
circulatory system process GO:0003013 87 0.030
catechol containing compound metabolic process GO:0009712 2 0.030
ventricular cardiac myofibril assembly GO:0055005 4 0.029
cardiac chamber development GO:0003205 19 0.029
neurotransmitter secretion GO:0007269 2 0.029
negative regulation of muscle contraction GO:0045932 1 0.029
regulation of muscle system process GO:0090257 5 0.029
dorsal aorta morphogenesis GO:0035912 3 0.028
cell migration involved in heart formation GO:0060974 10 0.028
cellular aromatic compound metabolic process GO:0006725 295 0.028
cell matrix adhesion GO:0007160 4 0.028
cell motility GO:0048870 244 0.028
oligodendrocyte cell fate specification GO:0021778 4 0.028
cytosolic calcium ion homeostasis GO:0051480 7 0.028
glial cell migration GO:0008347 3 0.027
regulation of binding GO:0051098 3 0.026
cellular nitrogen compound metabolic process GO:0034641 290 0.026
protein metabolic process GO:0019538 183 0.025
divalent inorganic cation transport GO:0072511 21 0.025
response to mechanical stimulus GO:0009612 24 0.025
outflow tract morphogenesis GO:0003151 1 0.025
venous blood vessel morphogenesis GO:0048845 3 0.025
cardiac conduction system development GO:0003161 1 0.025
dorsal aorta development GO:0035907 4 0.025
specification of axis polarity GO:0065001 4 0.024
cellular component assembly GO:0022607 170 0.024
cellular modified amino acid metabolic process GO:0006575 3 0.024
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.024
cellular component movement GO:0006928 335 0.024
regulation of transport GO:0051049 45 0.024
modification dependent macromolecule catabolic process GO:0043632 3 0.024
regulation of mesenchymal cell proliferation GO:0010464 1 0.024
regulation of metal ion transport GO:0010959 4 0.023
cytoskeleton organization GO:0007010 96 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
neurotransmitter transport GO:0006836 2 0.023
cardiac muscle contraction GO:0060048 6 0.023
Rat
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.023
regulation of translational initiation GO:0006446 1 0.022
antimicrobial humoral response GO:0019730 2 0.022
locomotory behavior GO:0007626 34 0.022
multi organism reproductive process GO:0044703 36 0.022
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.022
calcium mediated signaling GO:0019722 2 0.022
cellular localization GO:0051641 97 0.022
cardiac cell development GO:0055006 21 0.022
homeostatic process GO:0042592 142 0.021
regulation of membrane repolarization GO:0060306 1 0.021
oxoacid metabolic process GO:0043436 31 0.021
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.021
cellular response to chemical stimulus GO:0070887 157 0.021
lipid catabolic process GO:0016042 4 0.021
heart rudiment development GO:0003313 8 0.021
definitive hemopoiesis GO:0060216 18 0.021
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.021
er nucleus signaling pathway GO:0006984 2 0.020
small molecule catabolic process GO:0044282 3 0.020
atrial cardiac muscle cell differentiation GO:0055011 5 0.020
regulation of cell communication GO:0010646 232 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
cellular response to organic cyclic compound GO:0071407 38 0.020
homeostasis of number of cells GO:0048872 62 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
negative regulation of cellular process GO:0048523 283 0.020
ubiquitin dependent protein catabolic process GO:0006511 3 0.020
single organism organelle organization GO:1902589 199 0.020
regulation of transmembrane transporter activity GO:0022898 2 0.020
embryonic skeletal system morphogenesis GO:0048704 93 0.020
cellular ion homeostasis GO:0006873 17 0.019
meiotic nuclear division GO:0007126 4 0.019
regulation of cellular component movement GO:0051270 55 0.019
translational initiation GO:0006413 3 0.019
intracellular signal transduction GO:0035556 85 0.019
regulation of transporter activity GO:0032409 2 0.019
response to external stimulus GO:0009605 264 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.019
cytosolic calcium ion transport GO:0060401 3 0.018
cardiogenic plate morphogenesis GO:0003142 1 0.018
protein targeting to nucleus GO:0044744 3 0.018
regulation of neurotransmitter secretion GO:0046928 1 0.018
regulation of skeletal muscle cell differentiation GO:2001014 1 0.018
cellular protein catabolic process GO:0044257 4 0.018
membrane hyperpolarization GO:0060081 1 0.018
negative regulation of synapse assembly GO:0051964 2 0.018
divalent metal ion transport GO:0070838 20 0.018
establishment of localization in cell GO:0051649 77 0.018
positive regulation of catabolic process GO:0009896 4 0.017
monocyte differentiation GO:0030224 2 0.017
carbohydrate derivative metabolic process GO:1901135 61 0.017
erythrocyte development GO:0048821 24 0.017
small molecule metabolic process GO:0044281 77 0.017
organic acid metabolic process GO:0006082 31 0.017
regulation of actin filament based movement GO:1903115 1 0.017
central nervous system development GO:0007417 387 0.017
death GO:0016265 121 0.016
response to steroid hormone GO:0048545 35 0.016
purine ribonucleotide metabolic process GO:0009150 27 0.016
axon guidance GO:0007411 86 0.016
regulation of actin filament based process GO:0032970 9 0.016
cardiac myofibril assembly GO:0055003 9 0.016
cardiac ventricle development GO:0003231 9 0.016
regulation of sequestering of calcium ion GO:0051282 4 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
glial cell fate specification GO:0021780 4 0.016
negative regulation of stem cell differentiation GO:2000737 2 0.016
atrioventricular valve morphogenesis GO:0003181 6 0.016
specification of organ identity GO:0010092 2 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
striated muscle contraction GO:0006941 12 0.015
Rat
phosphorus metabolic process GO:0006793 109 0.015
nucleobase containing small molecule metabolic process GO:0055086 32 0.015
caudal fin development GO:0033336 9 0.015
skeletal muscle organ development GO:0060538 78 0.015
Rat
establishment of mitotic spindle localization GO:0040001 12 0.015
muscle tissue morphogenesis GO:0060415 7 0.015
positive regulation of transport GO:0051050 2 0.015
action potential GO:0001508 19 0.015
organic substance biosynthetic process GO:1901576 289 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
organic substance catabolic process GO:1901575 28 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
negative regulation of myeloid cell differentiation GO:0045638 1 0.014
response to endogenous stimulus GO:0009719 83 0.014
cilium morphogenesis GO:0060271 85 0.014
cellular biosynthetic process GO:0044249 286 0.014
nucleotide metabolic process GO:0009117 28 0.014
pronephros development GO:0048793 69 0.014
neuron projection morphogenesis GO:0048812 161 0.014
embryonic camera type eye formation GO:0060900 10 0.014
positive regulation of skeletal muscle tissue development GO:0048643 1 0.014
cellular divalent inorganic cation homeostasis GO:0072503 13 0.014
regulation of production of molecular mediator of immune response GO:0002700 1 0.014
plasma membrane repair GO:0001778 2 0.014
single organism transport GO:0044765 206 0.014
regulation of cell substrate adhesion GO:0010810 1 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
endocardial cushion development GO:0003197 6 0.014
primitive hemopoiesis GO:0060215 27 0.013
erythrocyte homeostasis GO:0034101 55 0.013
cell surface receptor signaling pathway GO:0007166 325 0.013
artery development GO:0060840 22 0.013
sequestering of calcium ion GO:0051208 3 0.013
compound eye development GO:0048749 2 0.013
negative regulation of striated muscle tissue development GO:0045843 2 0.013
syncytium formation GO:0006949 12 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
cellular homeostasis GO:0019725 26 0.013
auditory receptor cell fate determination GO:0042668 2 0.013
hematopoietic progenitor cell differentiation GO:0002244 23 0.013
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.013
ribose phosphate metabolic process GO:0019693 27 0.013
response to unfolded protein GO:0006986 2 0.013
regulation of establishment of planar polarity GO:0090175 4 0.013
purine ribonucleoside metabolic process GO:0046128 10 0.013
negative regulation of cell death GO:0060548 60 0.013
regulation of cytokine production GO:0001817 3 0.013
lipid metabolic process GO:0006629 52 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
fatty acid beta oxidation GO:0006635 1 0.013
endoplasmic reticulum unfolded protein response GO:0030968 2 0.012
specification of organ position GO:0010159 3 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
segmentation GO:0035282 97 0.012
mitochondrion organization GO:0007005 4 0.012
multi organism process GO:0051704 134 0.012
cellular response to unfolded protein GO:0034620 2 0.012
nuclear import GO:0051170 3 0.012
biosynthetic process GO:0009058 294 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
regulation of organ growth GO:0046620 3 0.012
cell cell signaling GO:0007267 52 0.012
cell migration involved in gastrulation GO:0042074 79 0.012
wnt signaling pathway GO:0016055 80 0.012
cellular potassium ion transport GO:0071804 10 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.012
protein localization to nucleus GO:0034504 3 0.012
nucleoside phosphate metabolic process GO:0006753 28 0.012
post embryonic organ development GO:0048569 4 0.012
nuclear transport GO:0051169 4 0.011
negative regulation of leukocyte differentiation GO:1902106 1 0.011
pronephric duct development GO:0039022 13 0.011
macromolecular complex assembly GO:0065003 35 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
negative regulation of biological process GO:0048519 304 0.011
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
neuromuscular process controlling balance GO:0050885 3 0.011
carbohydrate homeostasis GO:0033500 1 0.011
purine nucleoside monophosphate metabolic process GO:0009126 5 0.011
post embryonic morphogenesis GO:0009886 4 0.011
negative regulation of muscle tissue development GO:1901862 2 0.011
regulation of inner ear receptor cell differentiation GO:2000980 1 0.011
canonical wnt signaling pathway involved in heart development GO:0061316 1 0.011
glucocorticoid biosynthetic process GO:0006704 1 0.011
myoblast fusion GO:0007520 10 0.011
endocardium formation GO:0060214 1 0.011
ion transport GO:0006811 114 0.011
regulation of signaling GO:0023051 235 0.011
monocarboxylic acid catabolic process GO:0072329 3 0.011
regulation of reproductive process GO:2000241 4 0.011
sensory perception of mechanical stimulus GO:0050954 16 0.011
positive regulation of muscle tissue development GO:1901863 1 0.010
glucose homeostasis GO:0042593 1 0.010
chemical homeostasis GO:0048878 49 0.010
tissue remodeling GO:0048771 4 0.010
embryonic neurocranium morphogenesis GO:0048702 15 0.010
primitive erythrocyte differentiation GO:0060319 5 0.010
modification dependent protein catabolic process GO:0019941 3 0.010
regulation of protein binding GO:0043393 3 0.010
response to organic substance GO:0010033 153 0.010
female meiosis chromosome segregation GO:0016321 1 0.010
protein import into nucleus GO:0006606 3 0.010

cmlc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.742
muscular disease DOID:0080000 0 0.742
heart disease DOID:114 0 0.742
cardiomyopathy DOID:0050700 0 0.742
disease of anatomical entity DOID:7 0 0.742
intrinsic cardiomyopathy DOID:0060036 0 0.742
cardiovascular system disease DOID:1287 0 0.742
musculoskeletal system disease DOID:17 0 0.742
muscle tissue disease DOID:66 0 0.742
hypertrophic cardiomyopathy DOID:11984 0 0.171
dilated cardiomyopathy DOID:12930 0 0.025
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.014