Danio rerio

0 known processes

col11a1a

collagen, type XI, alpha 1a

(Aliases: wu:fc11b03,zgc:158335,wu:fb34e11)

col11a1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
extracellular structure organization GO:0043062 27 0.569
Mouse
digestive tract development GO:0048565 265 0.341
Human
embryonic organ morphogenesis GO:0048562 274 0.312
Mouse
cellular component movement GO:0006928 335 0.280
extracellular matrix organization GO:0030198 27 0.267
Mouse
hemostasis GO:0007599 13 0.259
skeletal system development GO:0001501 181 0.241
Zebrafish Mouse
coagulation GO:0050817 13 0.225
chondrocyte development GO:0002063 4 0.221
Mouse
multicellular organismal metabolic process GO:0044236 2 0.215
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.211
determination of bilateral symmetry GO:0009855 204 0.211
cartilage development GO:0051216 96 0.204
Zebrafish Mouse
positive regulation of cellular component biogenesis GO:0044089 3 0.200
regulation of establishment of protein localization GO:0070201 4 0.199
nucleocytoplasmic transport GO:0006913 4 0.195
digestive system development GO:0055123 289 0.183
Human
collagen biosynthetic process GO:0032964 2 0.174
digestive tract morphogenesis GO:0048546 231 0.164
Human
regulation of protein targeting GO:1903533 2 0.161
cellular response to external stimulus GO:0071496 2 0.159
regulation of intracellular protein transport GO:0033157 3 0.158
regulation of protein localization to nucleus GO:1900180 2 0.151
regulation of epithelial cell proliferation GO:0050678 3 0.146
chordate embryonic development GO:0043009 271 0.144
Mouse
single organism nuclear import GO:1902593 3 0.139
regulation of signal transduction GO:0009966 225 0.138
regulation of protein import into nucleus GO:0042306 2 0.138
taxis GO:0042330 109 0.135
protein targeting to nucleus GO:0044744 3 0.132
convergent extension GO:0060026 118 0.129
growth plate cartilage development GO:0003417 2 0.126
epithelial cell morphogenesis GO:0003382 2 0.125
gastrulation GO:0007369 208 0.123
Human
blood coagulation GO:0007596 12 0.113
protein import into nucleus GO:0006606 3 0.111
regulation of multicellular organismal metabolic process GO:0044246 2 0.109
collagen metabolic process GO:0032963 2 0.107
regionalization GO:0003002 274 0.106
erk1 and erk2 cascade GO:0070371 4 0.096
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.094
regulation of cell activation GO:0050865 1 0.093
regulation of cell communication GO:0010646 232 0.091
specification of symmetry GO:0009799 204 0.089
hormone biosynthetic process GO:0042446 3 0.087
endochondral bone growth GO:0003416 2 0.086
organic substance biosynthetic process GO:1901576 289 0.085
growth GO:0040007 174 0.081
Zebrafish
regulation of stem cell differentiation GO:2000736 4 0.081
morphogenesis of an epithelial sheet GO:0002011 49 0.080
embryo development ending in birth or egg hatching GO:0009792 271 0.077
Mouse
signal transduction GO:0007165 455 0.077
negative regulation of biological process GO:0048519 304 0.077
regulation of blood coagulation GO:0030193 1 0.076
glycosaminoglycan metabolic process GO:0030203 9 0.073
morphogenesis of an epithelium GO:0002009 333 0.069
rho protein signal transduction GO:0007266 5 0.069
protein import GO:0017038 3 0.068
convergent extension involved in axis elongation GO:0060028 26 0.068
positive regulation of cytokine production GO:0001819 2 0.067
regulation of cytoplasmic transport GO:1903649 4 0.066
response to wounding GO:0009611 116 0.066
Zebrafish
lipid biosynthetic process GO:0008610 22 0.065
embryonic limb morphogenesis GO:0030326 2 0.065
pectoral fin development GO:0033339 50 0.064
Zebrafish
negative regulation of signal transduction GO:0009968 94 0.063
nuclear import GO:0051170 3 0.062
multicellular organismal macromolecule metabolic process GO:0044259 2 0.060
positive regulation of cellular amine metabolic process GO:0033240 0 0.060
regulation of cytokine production GO:0001817 3 0.059
protein localization to nucleus GO:0034504 3 0.057
response to organic substance GO:0010033 153 0.056
establishment of protein localization to organelle GO:0072594 4 0.055
response to carbohydrate GO:0009743 3 0.055
regulation of cellular amine metabolic process GO:0033238 0 0.055
cell substrate adhesion GO:0031589 4 0.054
response to chemical GO:0042221 320 0.054
multicellular organismal homeostasis GO:0048871 29 0.054
sensory organ development GO:0007423 393 0.054
Mouse
small molecule metabolic process GO:0044281 77 0.054
response to stress GO:0006950 263 0.053
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 195 0.053
single organism biosynthetic process GO:0044711 71 0.052
neural crest cell development GO:0014032 62 0.052
embryonic organ development GO:0048568 381 0.051
Zebrafish Mouse
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.050
cell motility GO:0048870 244 0.050
positive regulation of cell activation GO:0050867 1 0.050
wound healing GO:0042060 90 0.050
Zebrafish
negative regulation of epithelial cell proliferation GO:0050680 1 0.049
response to nutrient GO:0007584 3 0.047
developmental growth involved in morphogenesis GO:0060560 86 0.047
canonical wnt signaling pathway GO:0060070 48 0.046
negative regulation of cellular process GO:0048523 283 0.046
response to monosaccharide GO:0034284 3 0.043
stem cell differentiation GO:0048863 117 0.042
regulation of wound healing GO:0061041 2 0.042
cell surface receptor signaling pathway GO:0007166 325 0.041
cellular response to extracellular stimulus GO:0031668 2 0.040
cell migration GO:0016477 237 0.039
embryonic skeletal system morphogenesis GO:0048704 93 0.039
Mouse
fin morphogenesis GO:0033334 53 0.038
Zebrafish
embryonic cranial skeleton morphogenesis GO:0048701 90 0.038
extracellular matrix constituent secretion GO:0070278 3 0.038
lateral inhibition GO:0046331 1 0.037
negative regulation of signaling GO:0023057 96 0.037
regulation of wnt signaling pathway GO:0030111 53 0.037
system process GO:0003008 185 0.036
Human
cell adhesion GO:0007155 40 0.036
nuclear transport GO:0051169 4 0.036
ras protein signal transduction GO:0007265 7 0.036
embryonic skeletal system development GO:0048706 97 0.035
Mouse
embryonic viscerocranium morphogenesis GO:0048703 52 0.035
positive regulation of blood circulation GO:1903524 2 0.035
regulation of multicellular organismal process GO:0051239 277 0.035
Zebrafish
negative regulation of angiogenesis GO:0016525 7 0.034
developmental growth GO:0048589 166 0.034
Zebrafish
extrinsic apoptotic signaling pathway GO:0097191 3 0.034
biosynthetic process GO:0009058 294 0.033
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.033
optic placode formation GO:0001743 4 0.032
regulation of body fluid levels GO:0050878 16 0.031
protein complex subunit organization GO:0071822 46 0.031
Mouse
mesenchymal cell development GO:0014031 78 0.031
regulation of blood pressure GO:0008217 1 0.031
cellular component biogenesis GO:0044085 178 0.030
mesenchymal cell differentiation GO:0048762 87 0.030
cartilage development involved in endochondral bone morphogenesis GO:0060351 8 0.030
negative regulation of dna metabolic process GO:0051053 4 0.030
angiogenesis GO:0001525 158 0.030
mesenchyme development GO:0060485 127 0.030
response to mechanical stimulus GO:0009612 24 0.030
Human Zebrafish
cellular amine metabolic process GO:0044106 2 0.029
diterpenoid metabolic process GO:0016101 15 0.029
response to corticosteroid GO:0031960 1 0.029
positive regulation of ras protein signal transduction GO:0046579 1 0.029
regulation of signaling GO:0023051 235 0.029
axis elongation GO:0003401 31 0.029
positive regulation of apoptotic signaling pathway GO:2001235 1 0.029
cellular response to retinoic acid GO:0071300 1 0.028
regulation of tube size GO:0035150 2 0.028
heart morphogenesis GO:0003007 156 0.028
Mouse
regulation of cellular response to growth factor stimulus GO:0090287 35 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
response to external stimulus GO:0009605 264 0.027
Human Zebrafish
response to growth factor GO:0070848 39 0.027
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.027
activation of mapk activity GO:0000187 3 0.027
organism emergence from protective structure GO:0071684 4 0.026
regulation of hemostasis GO:1900046 1 0.026
determination of heart left right asymmetry GO:0061371 117 0.026
regulation of calcium ion transport GO:0051924 2 0.026
collagen fibril organization GO:0030199 1 0.026
Mouse
single organism organelle organization GO:1902589 199 0.026
regulation of response to stimulus GO:0048583 269 0.026
cellular response to xenobiotic stimulus GO:0071466 35 0.026
tube morphogenesis GO:0035239 349 0.025
Human
regulation of cell substrate adhesion GO:0010810 1 0.025
negative regulation of cell communication GO:0010648 96 0.025
chondroitin sulfate proteoglycan metabolic process GO:0050654 8 0.025
cognition GO:0050890 1 0.025
positive regulation of jnk cascade GO:0046330 3 0.025
basement membrane assembly GO:0070831 3 0.025
cell morphogenesis GO:0000902 289 0.025
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.025
epiboly GO:0090504 41 0.025
convergent extension involved in gastrulation GO:0060027 71 0.025
regulation of collagen metabolic process GO:0010712 2 0.025
eye morphogenesis GO:0048592 144 0.025
stem cell development GO:0048864 82 0.024
embryonic camera type eye morphogenesis GO:0048596 19 0.024
cell projection assembly GO:0030031 64 0.023
regulation of protein transport GO:0051223 3 0.023
phosphorus metabolic process GO:0006793 109 0.023
negative regulation of embryonic development GO:0045992 11 0.023
protein secretion GO:0009306 1 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
homeostatic process GO:0042592 142 0.022
small gtpase mediated signal transduction GO:0007264 8 0.022
macromolecule biosynthetic process GO:0009059 227 0.021
cellular response to chemical stimulus GO:0070887 157 0.021
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.021
oligodendrocyte differentiation GO:0048709 23 0.021
positive regulation of cytoskeleton organization GO:0051495 3 0.021
phagocytosis GO:0006909 3 0.021
connective tissue development GO:0061448 99 0.021
Zebrafish Mouse
cellular response to growth factor stimulus GO:0071363 39 0.021
hormone metabolic process GO:0042445 19 0.021
cellular component assembly GO:0022607 170 0.021
positive regulation of stress activated mapk cascade GO:0032874 3 0.021
cellular response to nutrient levels GO:0031669 2 0.021
larval development GO:0002164 2 0.020
ion homeostasis GO:0050801 41 0.020
membrane invagination GO:0010324 1 0.020
microtubule based process GO:0007017 60 0.019
positive regulation of lipid metabolic process GO:0045834 1 0.019
protein metabolic process GO:0019538 183 0.019
Mouse
locomotion GO:0040011 313 0.019
regulation of rho protein signal transduction GO:0035023 2 0.019
cellular response to radiation GO:0071478 4 0.019
phagocytosis engulfment GO:0006911 1 0.019
cellular component assembly involved in morphogenesis GO:0010927 107 0.019
single organism metabolic process GO:0044710 217 0.019
negative chemotaxis GO:0050919 1 0.018
regulation of muscle contraction GO:0006937 3 0.018
ossification GO:0001503 23 0.018
Zebrafish
negative regulation of multicellular organismal process GO:0051241 69 0.018
cytosolic calcium ion transport GO:0060401 3 0.018
response to fibroblast growth factor GO:0071774 22 0.018
cellular protein catabolic process GO:0044257 4 0.018
response to hexose GO:0009746 3 0.018
regulation of catenin import into nucleus GO:0035412 2 0.018
glycoprotein metabolic process GO:0009100 23 0.018
Mouse
skeletal system morphogenesis GO:0048705 102 0.018
Mouse
establishment of localization in cell GO:0051649 77 0.017
regulation of biological quality GO:0065008 263 0.017
cellular component morphogenesis GO:0032989 336 0.017
cell projection morphogenesis GO:0048858 244 0.017
axonal defasciculation GO:0007414 2 0.017
intracellular signal transduction GO:0035556 85 0.017
response to estrogen GO:0043627 27 0.016
response to abiotic stimulus GO:0009628 122 0.016
Human Zebrafish
sensory perception of mechanical stimulus GO:0050954 16 0.016
Human
regulation of reactive oxygen species metabolic process GO:2000377 2 0.016
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.016
death GO:0016265 121 0.016
regulation of blood vessel size GO:0050880 2 0.016
positive regulation of epithelial cell migration GO:0010634 2 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
determination of left right symmetry GO:0007368 179 0.016
negative regulation of dna replication GO:0008156 2 0.016
appendage development GO:0048736 80 0.015
Zebrafish
oxoacid metabolic process GO:0043436 31 0.015
cellular component disassembly GO:0022411 1 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
cell part morphogenesis GO:0032990 246 0.015
regulation of reproductive process GO:2000241 4 0.015
response to acid chemical GO:0001101 17 0.015
morphogenesis of an epithelial fold GO:0060571 1 0.015
embryonic skeletal joint development GO:0072498 3 0.015
regulation of metal ion transport GO:0010959 4 0.015
smooth muscle contraction GO:0006939 2 0.015
positive regulation of apoptotic process GO:0043065 29 0.015
cell cycle process GO:0022402 53 0.015
cellular localization GO:0051641 97 0.015
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.014
platelet activation GO:0030168 3 0.014
inner ear development GO:0048839 126 0.014
Mouse
negative regulation of cellular component movement GO:0051271 18 0.014
regulation of cell shape GO:0008360 1 0.014
aminoglycan metabolic process GO:0006022 9 0.014
somatic stem cell maintenance GO:0035019 1 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
cell projection organization GO:0030030 284 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
positive regulation of metabolic process GO:0009893 108 0.014
aging GO:0007568 2 0.014
bmp signaling pathway GO:0030509 52 0.013
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
chemotaxis GO:0006935 104 0.013
cellular response to starvation GO:0009267 1 0.013
anatomical structure homeostasis GO:0060249 36 0.013
response to inorganic substance GO:0010035 38 0.013
organic acid metabolic process GO:0006082 31 0.013
bone morphogenesis GO:0060349 11 0.013
alcohol biosynthetic process GO:0046165 2 0.013
positive regulation of cell substrate adhesion GO:0010811 1 0.012
response to alkaloid GO:0043279 2 0.012
cell death GO:0008219 121 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
regulation of coagulation GO:0050818 2 0.012
regulation of localization GO:0032879 104 0.012
negative regulation of developmental process GO:0051093 65 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.012
photoreceptor cell differentiation GO:0046530 55 0.012
actin mediated cell contraction GO:0070252 1 0.012
intracellular transport GO:0046907 32 0.012
cytoskeleton organization GO:0007010 96 0.012
response to endogenous stimulus GO:0009719 83 0.012
bone mineralization GO:0030282 9 0.012
response to metal ion GO:0010038 34 0.012
regulation of protein modification process GO:0031399 29 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
spindle assembly GO:0051225 2 0.011
single organism cell adhesion GO:0098602 29 0.011
response to drug GO:0042493 3 0.011
camera type eye development GO:0043010 222 0.011
embryonic camera type eye development GO:0031076 29 0.011
interspecies interaction between organisms GO:0044419 4 0.011
photoreceptor cell development GO:0042461 40 0.011
protein modification process GO:0036211 100 0.011
female sex differentiation GO:0046660 4 0.011
cytokinesis GO:0000910 3 0.011
positive regulation of immune effector process GO:0002699 3 0.011
regulation of dna replication GO:0006275 3 0.011
generation of neurons GO:0048699 385 0.011
cellular lipid metabolic process GO:0044255 36 0.011
epidermis development GO:0008544 48 0.011
cell activation GO:0001775 16 0.011
positive regulation of secretion GO:0051047 1 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
negative regulation of wound healing GO:0061045 1 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
regulation of programmed cell death GO:0043067 101 0.011
regulation of lipase activity GO:0060191 2 0.011
neural crest cell differentiation GO:0014033 72 0.011
positive regulation of cell communication GO:0010647 56 0.011
sensory organ morphogenesis GO:0090596 200 0.011
Mouse
tissue homeostasis GO:0001894 25 0.011
response to vitamin GO:0033273 3 0.011
regulation of cell death GO:0010941 103 0.011
cilium morphogenesis GO:0060271 85 0.011
negative regulation of stem cell differentiation GO:2000737 2 0.011
mucopolysaccharide metabolic process GO:1903510 2 0.011
sprouting angiogenesis GO:0002040 53 0.011
estrogen metabolic process GO:0008210 2 0.011
meiotic nuclear division GO:0007126 4 0.011
cellular response to endogenous stimulus GO:0071495 68 0.010
neuron projection morphogenesis GO:0048812 161 0.010
androgen metabolic process GO:0008209 2 0.010
macromolecule modification GO:0043412 111 0.010
organ growth GO:0035265 12 0.010
positive regulation of transport GO:0051050 2 0.010
inner ear receptor cell fate commitment GO:0060120 4 0.010
regulation of epithelial to mesenchymal transition GO:0010717 3 0.010
regulation of cytokine biosynthetic process GO:0042035 1 0.010
myotome development GO:0061055 1 0.010
skin development GO:0043588 54 0.010
response to lipid GO:0033993 60 0.010
regulation of intracellular signal transduction GO:1902531 57 0.010
somite development GO:0061053 96 0.010
skin morphogenesis GO:0043589 7 0.010
microtubule polymerization or depolymerization GO:0031109 3 0.010
mesenchymal cell proliferation GO:0010463 1 0.010
transport GO:0006810 220 0.010

col11a1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.150
musculoskeletal system disease DOID:17 0 0.150
connective tissue disease DOID:65 0 0.150
bone development disease DOID:0080006 0 0.070
bone disease DOID:0080001 0 0.070
sensory system disease DOID:0050155 0 0.024
eye and adnexa disease DOID:1492 0 0.024
nervous system disease DOID:863 0 0.024
osteochondrodysplasia DOID:2256 0 0.020
immune system disease DOID:2914 0 0.018
eye disease DOID:5614 0 0.014
retinal disease DOID:5679 0 0.010