Danio rerio

31 known processes

col18a1

collagen type XVIII, alpha 1

(Aliases: wu:fk02h12,wu:fb47h10,wu:fc96d06,wu:fb77g12,cb529,cb371,sb:cb529,wu:fc50f04,fc96d06)

col18a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell projection morphogenesis GO:0048858 244 0.709
Worm
generation of neurons GO:0048699 385 0.238
Worm
cell morphogenesis involved in differentiation GO:0000904 195 0.219
Mouse Worm
response to vitamin b3 GO:0033552 2 0.215
neuron projection development GO:0031175 180 0.179
Worm
cell part morphogenesis GO:0032990 246 0.164
Worm
axon development GO:0061564 166 0.163
Worm
cell morphogenesis GO:0000902 289 0.151
Mouse Worm
embryonic limb morphogenesis GO:0030326 2 0.122
somite development GO:0061053 96 0.120
synaptic transmission cholinergic GO:0007271 4 0.114
Worm
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.113
Worm
neuron projection morphogenesis GO:0048812 161 0.112
Worm
regulation of stem cell proliferation GO:0072091 2 0.107
regulation of neural precursor cell proliferation GO:2000177 3 0.102
regulation of cell substrate adhesion GO:0010810 1 0.099
positive regulation of neural precursor cell proliferation GO:2000179 1 0.097
single organism metabolic process GO:0044710 217 0.097
regulation of mrna processing GO:0050684 3 0.096
cell adhesion GO:0007155 40 0.096
protein complex assembly GO:0006461 30 0.091
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.082
axonogenesis GO:0007409 152 0.077
Worm
neuroblast proliferation GO:0007405 2 0.070
somitogenesis GO:0001756 87 0.069
regulation of cytoplasmic transport GO:1903649 4 0.068
oxoacid metabolic process GO:0043436 31 0.067
regulation of intracellular protein transport GO:0033157 3 0.065
protein complex biogenesis GO:0070271 30 0.064
aromatic compound biosynthetic process GO:0019438 217 0.064
skeletal muscle organ development GO:0060538 78 0.063
stem cell proliferation GO:0072089 4 0.061
cellular component biogenesis GO:0044085 178 0.060
macromolecule localization GO:0033036 54 0.055
Worm
response to amino acid GO:0043200 2 0.053
macromolecular complex subunit organization GO:0043933 74 0.051
basement membrane assembly GO:0070831 3 0.051
cell surface receptor signaling pathway GO:0007166 325 0.049
protein localization to nucleus GO:0034504 3 0.047
cellular component morphogenesis GO:0032989 336 0.043
Mouse Worm
cellular response to oxygen levels GO:0071453 1 0.042
cellular component assembly GO:0022607 170 0.041
vasculogenesis GO:0001570 41 0.038
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.038
positive regulation of cell substrate adhesion GO:0010811 1 0.035
regulation of epithelial to mesenchymal transition GO:0010717 3 0.035
axon guidance GO:0007411 86 0.035
Worm
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.034
regulation of primary metabolic process GO:0080090 311 0.034
neuron development GO:0048666 262 0.034
Worm
neuron projection guidance GO:0097485 86 0.033
Worm
regulation of protein localization to nucleus GO:1900180 2 0.033
sensory perception of pain GO:0019233 1 0.033
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.032
response to nutrient GO:0007584 3 0.032
response to vitamin GO:0033273 3 0.031
positive regulation of transport GO:0051050 2 0.030
aging GO:0007568 2 0.030
cellular component disassembly GO:0022411 1 0.030
regulation of macromolecule biosynthetic process GO:0010556 225 0.029
muscle structure development GO:0061061 196 0.029
cell substrate adhesion GO:0031589 4 0.029
neuron differentiation GO:0030182 353 0.029
Worm
regulation of nitrogen compound metabolic process GO:0051171 251 0.028
organic substance biosynthetic process GO:1901576 289 0.027
signal transduction GO:0007165 455 0.026
type b pancreatic cell proliferation GO:0044342 1 0.026
taxis GO:0042330 109 0.026
Worm
proximal distal pattern formation GO:0009954 1 0.025
cellular response to hypoxia GO:0071456 1 0.025
protein oligomerization GO:0051259 7 0.024
positive regulation of stress activated mapk cascade GO:0032874 3 0.024
cellular response to extracellular stimulus GO:0031668 2 0.024
positive regulation of cell cycle GO:0045787 3 0.024
protein import GO:0017038 3 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
immunoglobulin mediated immune response GO:0016064 3 0.023
macromolecular complex assembly GO:0065003 35 0.023
chromosome organization GO:0051276 31 0.023
oxidation reduction process GO:0055114 41 0.023
visual perception GO:0007601 17 0.022
response to chemical GO:0042221 320 0.022
Worm
regulation of calcium ion transport GO:0051924 2 0.022
positive regulation of jnk cascade GO:0046330 3 0.022
mesenchymal cell development GO:0014031 78 0.021
cell migration GO:0016477 237 0.021
wound healing GO:0042060 90 0.021
nuclear division GO:0000280 23 0.021
ras protein signal transduction GO:0007265 7 0.020
regeneration GO:0031099 91 0.020
response to abiotic stimulus GO:0009628 122 0.020
blood vessel development GO:0001568 246 0.019
Mouse
small molecule metabolic process GO:0044281 77 0.019
protein localization to plasma membrane GO:0072659 1 0.019
regulation of cell matrix adhesion GO:0001952 1 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
negative regulation of kinase activity GO:0033673 4 0.018
3 utr mediated mrna stabilization GO:0070935 3 0.018
melanin metabolic process GO:0006582 2 0.018
long chain fatty acid biosynthetic process GO:0042759 1 0.018
single organism nuclear import GO:1902593 3 0.018
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.018
blood vessel endothelial cell migration GO:0043534 18 0.018
wnt signaling pathway GO:0016055 80 0.018
cytoskeleton organization GO:0007010 96 0.017
single organism organelle organization GO:1902589 199 0.017
embryo development ending in birth or egg hatching GO:0009792 271 0.017
biosynthetic process GO:0009058 294 0.017
hepatocyte proliferation GO:0072574 2 0.017
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.017
response to corticosteroid GO:0031960 1 0.017
system process GO:0003008 185 0.017
establishment of endothelial barrier GO:0061028 3 0.017
organelle fission GO:0048285 23 0.016
sprouting angiogenesis GO:0002040 53 0.016
protein metabolic process GO:0019538 183 0.016
neurotransmitter transport GO:0006836 2 0.016
muscle organ development GO:0007517 101 0.016
regulation of metal ion transport GO:0010959 4 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
regulation of smoothened signaling pathway GO:0008589 18 0.016
regulation of mrna stability GO:0043488 4 0.016
secondary metabolic process GO:0019748 3 0.015
gene expression GO:0010467 252 0.015
multicellular organism growth GO:0035264 4 0.015
protein heterooligomerization GO:0051291 1 0.015
rna stabilization GO:0043489 4 0.015
axon extension involved in axon guidance GO:0048846 10 0.015
organelle organization GO:0006996 227 0.015
nucleobase containing compound metabolic process GO:0006139 274 0.015
maintenance of location GO:0051235 4 0.015
trabecula formation GO:0060343 2 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
renal tubule morphogenesis GO:0061333 1 0.014
extracellular matrix organization GO:0030198 27 0.014
Mouse
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
muscle cell development GO:0055001 115 0.014
cellular response to decreased oxygen levels GO:0036294 1 0.014
cell projection organization GO:0030030 284 0.014
Worm
nephron tubule morphogenesis GO:0072078 1 0.014
smoothened signaling pathway GO:0007224 30 0.014
response to decreased oxygen levels GO:0036293 25 0.014
lipid storage GO:0019915 1 0.014
regulation of cell differentiation GO:0045595 142 0.014
stem cell maintenance GO:0019827 4 0.013
neurotransmitter secretion GO:0007269 2 0.013
trabecula morphogenesis GO:0061383 2 0.013
establishment of localization GO:0051234 244 0.013
segmentation GO:0035282 97 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
basement membrane organization GO:0071711 5 0.013
carbohydrate derivative biosynthetic process GO:1901137 43 0.013
protein import into nucleus GO:0006606 3 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
sarcomere organization GO:0045214 26 0.013
regulation of dna templated transcription in response to stress GO:0043620 0 0.013
positive regulation of cellular process GO:0048522 201 0.013
Mouse
regulation of neurogenesis GO:0050767 87 0.013
regulation of cardiac muscle tissue development GO:0055024 1 0.013
meiotic nuclear division GO:0007126 4 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
pectoral fin development GO:0033339 50 0.012
mitotic cell cycle embryonic GO:0045448 2 0.012
skeletal muscle tissue development GO:0007519 67 0.012
cellular aromatic compound metabolic process GO:0006725 295 0.012
axon extension GO:0048675 45 0.012
syncytium formation by plasma membrane fusion GO:0000768 12 0.012
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.012
protein targeting to nucleus GO:0044744 3 0.012
regulation of extent of cell growth GO:0061387 29 0.012
regulation of gtpase activity GO:0043087 2 0.012
regulation of protein transport GO:0051223 3 0.012
sensory perception of light stimulus GO:0050953 19 0.012
startle response GO:0001964 4 0.011
regulation of dendrite morphogenesis GO:0048814 3 0.011
segment specification GO:0007379 12 0.011
nephron epithelium morphogenesis GO:0072088 1 0.011
positive regulation of mesoderm development GO:2000382 1 0.011
leukocyte proliferation GO:0070661 1 0.011
polyol metabolic process GO:0019751 1 0.011
regulation of blood coagulation GO:0030193 1 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
cell substrate junction assembly GO:0007044 2 0.011
negative regulation of protein kinase b signaling GO:0051898 2 0.011
mesenchymal cell differentiation GO:0048762 87 0.011
regulation of gene expression GO:0010468 265 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.010
positive regulation of cell matrix adhesion GO:0001954 1 0.010
cellular nitrogen compound metabolic process GO:0034641 290 0.010
regulation of mrna splicing via spliceosome GO:0048024 3 0.010
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.010
lymphocyte proliferation GO:0046651 1 0.010
negative regulation of biological process GO:0048519 304 0.010
mesenchyme development GO:0060485 127 0.010
cortical actin cytoskeleton organization GO:0030866 1 0.010
notochord development GO:0030903 54 0.010

col18a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
musculoskeletal system disease DOID:17 0 0.020
connective tissue disease DOID:65 0 0.020
bone development disease DOID:0080006 0 0.019
bone disease DOID:0080001 0 0.019
bone remodeling disease DOID:0080005 0 0.019
nervous system disease DOID:863 0 0.011