Danio rerio

32 known processes

cpn1

carboxypeptidase N, polypeptide 1

(Aliases: cb1037,wu:fa99g08,fa99g08,zgc:77485)

cpn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to chemical GO:0042221 320 0.232
regulation of epithelial cell proliferation GO:0050678 3 0.219
system process GO:0003008 185 0.212
multicellular organismal metabolic process GO:0044236 2 0.192
response to stress GO:0006950 263 0.189
response to external stimulus GO:0009605 264 0.182
regulation of biological quality GO:0065008 263 0.149
Worm
regulation of multicellular organism growth GO:0040014 4 0.144
regulation of cellular metabolic process GO:0031323 320 0.139
larval development GO:0002164 2 0.123
blood vessel morphogenesis GO:0048514 216 0.119
regulation of response to stimulus GO:0048583 269 0.112
multicellular organism growth GO:0035264 4 0.112
head development GO:0060322 303 0.108
generation of neurons GO:0048699 385 0.107
lipid storage GO:0019915 1 0.104
regulation of macromolecule metabolic process GO:0060255 317 0.103
locomotion GO:0040011 313 0.101
digestive tract development GO:0048565 265 0.097
regulation of endothelial cell proliferation GO:0001936 1 0.096
response to carbohydrate GO:0009743 3 0.095
organic acid metabolic process GO:0006082 31 0.090
response to glucose GO:0009749 3 0.089
regulation of cell communication GO:0010646 232 0.088
response to hexose GO:0009746 3 0.086
cell surface receptor signaling pathway GO:0007166 325 0.084
response to organic substance GO:0010033 153 0.083
positive regulation of biological process GO:0048518 253 0.083
negative regulation of response to stimulus GO:0048585 104 0.081
morphogenesis of an epithelium GO:0002009 333 0.077
aging GO:0007568 2 0.077
angiogenesis GO:0001525 158 0.074
vasculature development GO:0001944 278 0.074
regulation of inflammatory response GO:0050727 2 0.074
central nervous system development GO:0007417 387 0.073
carboxylic acid metabolic process GO:0019752 22 0.070
cellular ketone metabolic process GO:0042180 11 0.068
sensory organ development GO:0007423 393 0.067
hemopoiesis GO:0030097 183 0.066
cellular amino acid metabolic process GO:0006520 7 0.065
organic substance biosynthetic process GO:1901576 289 0.064
regulation of cellular amino acid metabolic process GO:0006521 0 0.062
cellular component morphogenesis GO:0032989 336 0.062
single organism biosynthetic process GO:0044711 71 0.062
negative regulation of biological process GO:0048519 304 0.062
response to wounding GO:0009611 116 0.060
regulation of cellular amine metabolic process GO:0033238 0 0.059
amine metabolic process GO:0009308 2 0.059
g protein coupled receptor signaling pathway GO:0007186 74 0.059
carbohydrate biosynthetic process GO:0016051 1 0.058
regulation of multicellular organismal process GO:0051239 277 0.058
cellular component movement GO:0006928 335 0.057
negative regulation of cellular process GO:0048523 283 0.056
somite development GO:0061053 96 0.054
regulation of primary metabolic process GO:0080090 311 0.053
regulation of signal transduction GO:0009966 225 0.053
peptide transport GO:0015833 1 0.052
response to steroid hormone GO:0048545 35 0.052
hormone transport GO:0009914 2 0.052
regulation of binding GO:0051098 3 0.051
single organism localization GO:1902578 225 0.051
Worm
regulation of metabolic process GO:0019222 359 0.050
regulation of gene expression GO:0010468 265 0.049
signal transduction GO:0007165 455 0.047
neuron development GO:0048666 262 0.047
nucleic acid templated transcription GO:0097659 181 0.046
cellular amine metabolic process GO:0044106 2 0.046
response to monosaccharide GO:0034284 3 0.045
regeneration GO:0031099 91 0.045
small molecule metabolic process GO:0044281 77 0.045
specification of symmetry GO:0009799 204 0.045
negative regulation of multicellular organismal process GO:0051241 69 0.044
maintenance of location GO:0051235 4 0.044
determination of bilateral symmetry GO:0009855 204 0.044
regulation of synapse assembly GO:0051963 3 0.044
enzyme linked receptor protein signaling pathway GO:0007167 106 0.043
regulation of nitrogen compound metabolic process GO:0051171 251 0.043
response to axon injury GO:0048678 14 0.042
organonitrogen compound metabolic process GO:1901564 74 0.042
blood vessel development GO:0001568 246 0.041
positive regulation of cellular process GO:0048522 201 0.041
single organism metabolic process GO:0044710 217 0.040
neuron differentiation GO:0030182 353 0.040
positive regulation of metabolic process GO:0009893 108 0.039
circulatory system process GO:0003013 87 0.039
cell migration GO:0016477 237 0.039
rna localization GO:0006403 4 0.038
tyrosine phosphorylation of stat protein GO:0007260 1 0.038
response to glucocorticoid GO:0051384 1 0.038
regulation of hormone secretion GO:0046883 2 0.038
positive regulation of cellular metabolic process GO:0031325 94 0.037
brain development GO:0007420 293 0.037
synaptic growth at neuromuscular junction GO:0051124 2 0.037
organic cyclic compound metabolic process GO:1901360 301 0.037
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.037
heart contraction GO:0060047 71 0.036
regulation of cellular ketone metabolic process GO:0010565 7 0.036
cell morphogenesis involved in differentiation GO:0000904 195 0.036
cellular macromolecule metabolic process GO:0044260 391 0.036
negative regulation of signaling GO:0023057 96 0.036
blood circulation GO:0008015 87 0.036
tube morphogenesis GO:0035239 349 0.035
muscle structure development GO:0061061 196 0.035
regulation of localization GO:0032879 104 0.035
embryonic organ morphogenesis GO:0048562 274 0.035
regulation of jak stat cascade GO:0046425 3 0.035
regulation of biosynthetic process GO:0009889 250 0.034
intracellular mrna localization GO:0008298 1 0.034
fat soluble vitamin metabolic process GO:0006775 4 0.034
cellular nitrogen compound biosynthetic process GO:0044271 218 0.034
positive regulation of secretion by cell GO:1903532 1 0.034
embryonic organ development GO:0048568 381 0.034
ossification GO:0001503 23 0.033
developmental growth GO:0048589 166 0.033
striated muscle tissue development GO:0014706 110 0.033
response to vitamin GO:0033273 3 0.033
multicellular organismal response to stress GO:0033555 2 0.033
determination of left right symmetry GO:0007368 179 0.033
response to biotic stimulus GO:0009607 97 0.032
myeloid leukocyte differentiation GO:0002573 15 0.032
muscle organ development GO:0007517 101 0.032
cellular hormone metabolic process GO:0034754 19 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.031
positive regulation of catabolic process GO:0009896 4 0.031
regulation of wound healing GO:0061041 2 0.031
cellular nitrogen compound metabolic process GO:0034641 290 0.031
glucose homeostasis GO:0042593 1 0.031
regulation of locomotion GO:0040012 55 0.031
cellular response to external stimulus GO:0071496 2 0.030
embryo development ending in birth or egg hatching GO:0009792 271 0.030
cellular response to stress GO:0033554 62 0.030
regulation of protein transport GO:0051223 3 0.030
cellular response to chemical stimulus GO:0070887 157 0.029
proteolysis GO:0006508 38 0.029
Mouse Worm
negative regulation of mapk cascade GO:0043409 4 0.029
cell projection morphogenesis GO:0048858 244 0.028
regulation of cellular component movement GO:0051270 55 0.028
epithelial cell differentiation GO:0030855 116 0.028
gene expression GO:0010467 252 0.028
Worm
homeostatic process GO:0042592 142 0.028
positive regulation of secretion GO:0051047 1 0.028
stem cell maintenance GO:0019827 4 0.028
aromatic compound biosynthetic process GO:0019438 217 0.027
regulation of cytokine production GO:0001817 3 0.027
epithelial cell morphogenesis GO:0003382 2 0.027
regulation of transcription dna templated GO:0006355 213 0.027
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.026
heart process GO:0003015 71 0.026
immune system development GO:0002520 191 0.026
embryonic heart tube development GO:0035050 133 0.026
digestive system development GO:0055123 289 0.026
localization of cell GO:0051674 244 0.026
ventricular cardiac muscle tissue development GO:0003229 3 0.025
lipid metabolic process GO:0006629 52 0.025
stem cell division GO:0017145 1 0.025
positive regulation of endothelial cell migration GO:0010595 2 0.025
immune system process GO:0002376 241 0.025
eye development GO:0001654 277 0.025
cardiac muscle tissue development GO:0048738 48 0.025
rna biosynthetic process GO:0032774 181 0.025
extrinsic apoptotic signaling pathway GO:0097191 3 0.024
myeloid cell differentiation GO:0030099 86 0.024
regulation of cell motility GO:2000145 46 0.024
neuron projection development GO:0031175 180 0.024
negative regulation of defense response GO:0031348 2 0.024
multi organism process GO:0051704 134 0.024
regulation of developmental process GO:0050793 247 0.024
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.024
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.023
cellular response to extracellular stimulus GO:0031668 2 0.023
regulation of nucleic acid templated transcription GO:1903506 213 0.023
heterocycle biosynthetic process GO:0018130 215 0.023
rna metabolic process GO:0016070 219 0.023
axon regeneration GO:0031103 14 0.022
cellular lipid metabolic process GO:0044255 36 0.022
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.022
cell motility GO:0048870 244 0.022
regulation of molecular function GO:0065009 70 0.022
positive regulation of transport GO:0051050 2 0.022
regulation of response to stress GO:0080134 36 0.021
behavior GO:0007610 74 0.021
camera type eye development GO:0043010 222 0.021
tissue remodeling GO:0048771 4 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
cellular component disassembly GO:0022411 1 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.021
embryonic limb morphogenesis GO:0030326 2 0.021
cellular response to nutrient levels GO:0031669 2 0.021
tissue regeneration GO:0042246 74 0.020
positive regulation of macromolecule metabolic process GO:0010604 93 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
neuron projection regeneration GO:0031102 16 0.020
hematopoietic or lymphoid organ development GO:0048534 191 0.020
g1 s transition of mitotic cell cycle GO:0000082 1 0.020
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.020
cellular response to organic substance GO:0071310 105 0.020
carbohydrate homeostasis GO:0033500 1 0.019
oxoacid metabolic process GO:0043436 31 0.019
regulation of metal ion transport GO:0010959 4 0.019
protein metabolic process GO:0019538 183 0.019
Mouse Worm
sensory organ morphogenesis GO:0090596 200 0.019
nucleic acid metabolic process GO:0090304 244 0.019
ameboidal type cell migration GO:0001667 143 0.019
protein polymerization GO:0051258 4 0.019
phosphorylation GO:0016310 69 0.019
growth GO:0040007 174 0.019
cellular component assembly GO:0022607 170 0.019
intracellular signal transduction GO:0035556 85 0.019
radial glial cell differentiation GO:0060019 2 0.018
positive regulation of carbohydrate metabolic process GO:0045913 1 0.018
cell projection organization GO:0030030 284 0.018
adult behavior GO:0030534 2 0.018
phosphate containing compound metabolic process GO:0006796 108 0.018
cardiac cell development GO:0055006 21 0.018
positive regulation of rna biosynthetic process GO:1902680 57 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
regulation of catalytic activity GO:0050790 55 0.018
regulation of phosphate metabolic process GO:0019220 43 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
regulation of cell activation GO:0050865 1 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
regulation of organ growth GO:0046620 3 0.017
axon development GO:0061564 166 0.017
cellular biosynthetic process GO:0044249 286 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
neuron projection morphogenesis GO:0048812 161 0.017
microtubule polymerization GO:0046785 2 0.017
heterocycle metabolic process GO:0046483 290 0.017
embryonic heart tube morphogenesis GO:0003143 108 0.017
regulation of protein polymerization GO:0032271 2 0.017
cellular response to organic cyclic compound GO:0071407 38 0.017
regulation of erk1 and erk2 cascade GO:0070372 4 0.017
hormone secretion GO:0046879 2 0.017
cellular response to endogenous stimulus GO:0071495 68 0.017
cellular response to lipid GO:0071396 39 0.017
development of primary female sexual characteristics GO:0046545 4 0.017
microtubule polymerization or depolymerization GO:0031109 3 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
collagen metabolic process GO:0032963 2 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.017
negative regulation of epithelial cell proliferation GO:0050680 1 0.016
nephron tubule morphogenesis GO:0072078 1 0.016
nitrogen compound metabolic process GO:0006807 319 0.016
cell part morphogenesis GO:0032990 246 0.016
heart looping GO:0001947 94 0.016
response to antibiotic GO:0046677 1 0.016
heart development GO:0007507 313 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
spinal cord radial glial cell differentiation GO:0021531 2 0.016
germ line stem cell maintenance GO:0030718 2 0.016
response to radiation GO:0009314 51 0.016
regulation of tube size GO:0035150 2 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
single fertilization GO:0007338 3 0.015
regulation of developmental growth GO:0048638 38 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
inner ear development GO:0048839 126 0.015
proepicardium development GO:0003342 4 0.015
regulation of response to external stimulus GO:0032101 31 0.015
mitotic dna integrity checkpoint GO:0044774 4 0.015
alpha amino acid metabolic process GO:1901605 3 0.015
response to external biotic stimulus GO:0043207 97 0.015
negative regulation of signal transduction GO:0009968 94 0.015
lateral inhibition GO:0046331 1 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.014
developmental cell growth GO:0048588 52 0.014
regulation of embryonic development GO:0045995 47 0.014
regionalization GO:0003002 274 0.014
gtp catabolic process GO:0006184 2 0.014
cellular response to decreased oxygen levels GO:0036294 1 0.014
response to bacterium GO:0009617 58 0.014
determination of heart left right asymmetry GO:0061371 117 0.014
regulation of synapse organization GO:0050807 3 0.014
muscle tissue development GO:0060537 110 0.014
zymogen activation GO:0031638 3 0.014
osteoclast differentiation GO:0030316 1 0.013
cellular response to starvation GO:0009267 1 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.013
response to nutrient GO:0007584 3 0.013
epiboly GO:0090504 41 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
chemotaxis GO:0006935 104 0.013
single organism organelle organization GO:1902589 199 0.013
regulation of peptidase activity GO:0052547 23 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
positive regulation of developmental process GO:0051094 50 0.013
cell aging GO:0007569 2 0.013
endothelium development GO:0003158 25 0.013
taxis GO:0042330 109 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
negative regulation of cell communication GO:0010648 96 0.013
regulation of jun kinase activity GO:0043506 3 0.013
organelle assembly GO:0070925 110 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
negative regulation of developmental process GO:0051093 65 0.013
regulation of signaling GO:0023051 235 0.013
meiotic cell cycle process GO:1903046 3 0.013
stem cell differentiation GO:0048863 117 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
positive regulation of wound healing GO:0090303 1 0.012
muscle cell differentiation GO:0042692 139 0.012
regulation of body fluid levels GO:0050878 16 0.012
regulation of hormone levels GO:0010817 21 0.012
leukocyte differentiation GO:0002521 25 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
regulation of dendrite development GO:0050773 3 0.012
macromolecular complex disassembly GO:0032984 1 0.012
multicellular organismal macromolecule metabolic process GO:0044259 2 0.012
response to corticosteroid GO:0031960 1 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
regulation of cell migration GO:0030334 40 0.012
cell proliferation GO:0008283 80 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
cellular component biogenesis GO:0044085 178 0.012
biological adhesion GO:0022610 40 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.012
skeletal system development GO:0001501 181 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
positive regulation of gene expression GO:0010628 71 0.012
female sex differentiation GO:0046660 4 0.012
defense response GO:0006952 47 0.012
fatty acid biosynthetic process GO:0006633 4 0.012
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
cell morphogenesis GO:0000902 289 0.012
phosphorus metabolic process GO:0006793 109 0.012
wound healing GO:0042060 90 0.011
phagocytosis GO:0006909 3 0.011
response to abiotic stimulus GO:0009628 122 0.011
transcription dna templated GO:0006351 181 0.011
regulation of hemostasis GO:1900046 1 0.011
response to lipid GO:0033993 60 0.011
biosynthetic process GO:0009058 294 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
cellular respiration GO:0045333 3 0.011
photoreceptor cell fate commitment GO:0046552 1 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
actin filament based movement GO:0030048 1 0.011
positive regulation of cell division GO:0051781 2 0.011
regulation of protein targeting GO:1903533 2 0.011
axonogenesis GO:0007409 152 0.011
positive regulation of cell cycle GO:0045787 3 0.011
gastrulation GO:0007369 208 0.011
coagulation GO:0050817 13 0.011
post golgi vesicle mediated transport GO:0006892 1 0.011
regulation of rna metabolic process GO:0051252 224 0.011
protein complex disassembly GO:0043241 1 0.011
cellular response to oxygen levels GO:0071453 1 0.011
response to oxygen containing compound GO:1901700 55 0.011
water homeostasis GO:0030104 4 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
notochord development GO:0030903 54 0.011
lens fiber cell development GO:0070307 3 0.011
transport GO:0006810 220 0.011
Worm
cellular protein complex disassembly GO:0043624 1 0.011
regulation of lipid transport GO:0032368 4 0.011
cell growth GO:0016049 57 0.011
non canonical wnt signaling pathway involved in heart development GO:0061341 2 0.011
catabolic process GO:0009056 32 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
regulation of protein binding GO:0043393 3 0.011
regulation of cell proliferation GO:0042127 37 0.010
fertilization GO:0009566 3 0.010
regulation of blood vessel size GO:0050880 2 0.010
peptidyl serine modification GO:0018209 2 0.010
gtp metabolic process GO:0046039 4 0.010
vitamin metabolic process GO:0006766 11 0.010
heart morphogenesis GO:0003007 156 0.010
regulation of gtpase activity GO:0043087 2 0.010
regulation of intracellular signal transduction GO:1902531 57 0.010
regulation of calcium ion transport GO:0051924 2 0.010

cpn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.073
disease of metabolism DOID:0014667 0 0.049
inherited metabolic disorder DOID:655 0 0.049
cardiovascular system disease DOID:1287 0 0.017
nervous system disease DOID:863 0 0.011