Danio rerio

71 known processes

crb2a

crumbs homolog 2a

(Aliases: crb2)

crb2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
apical protein localization GO:0045176 6 1.000
asymmetric protein localization GO:0008105 6 0.999
maintenance of epithelial cell apical basal polarity GO:0045199 5 0.994
camera type eye development GO:0043010 222 0.991
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.986
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 11 0.986
sensory organ morphogenesis GO:0090596 200 0.985
establishment or maintenance of apical basal cell polarity GO:0035088 12 0.981
medulla oblongata development GO:0021550 4 0.977
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.976
maintenance of cell polarity GO:0030011 5 0.973
generation of neurons GO:0048699 385 0.971
Zebrafish
eye morphogenesis GO:0048592 144 0.967
neuron differentiation GO:0030182 353 0.962
Zebrafish
retina morphogenesis in camera type eye GO:0060042 79 0.961
sensory organ development GO:0007423 393 0.913
regulation of wnt signaling pathway GO:0030111 53 0.911
Zebrafish
establishment or maintenance of bipolar cell polarity GO:0061245 12 0.905
establishment or maintenance of cell polarity GO:0007163 29 0.903
eye development GO:0001654 277 0.872
retina development in camera type eye GO:0060041 146 0.860
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.858
photoreceptor cell differentiation GO:0046530 55 0.834
Zebrafish
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.825
biological adhesion GO:0022610 40 0.816
cilium organization GO:0044782 71 0.792
Zebrafish
single organism organelle organization GO:1902589 199 0.777
Zebrafish
pigmentation GO:0043473 85 0.736
establishment of monopolar cell polarity GO:0061162 2 0.733
system process GO:0003008 185 0.731
Zebrafish
maintenance of apical basal cell polarity GO:0035090 5 0.715
embryo development ending in birth or egg hatching GO:0009792 271 0.707
neuron development GO:0048666 262 0.703
Zebrafish
cilium morphogenesis GO:0060271 85 0.625
Zebrafish
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.613
cell part morphogenesis GO:0032990 246 0.604
Zebrafish
cell projection organization GO:0030030 284 0.559
Zebrafish
neural nucleus development GO:0048857 15 0.554
neural tube formation GO:0001841 16 0.549
establishment of epithelial cell polarity GO:0090162 2 0.537
establishment of spindle orientation GO:0051294 10 0.535
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.530
regulation of glucose import GO:0046324 1 0.517
primary neural tube formation GO:0014020 1 0.507
wnt signaling pathway GO:0016055 80 0.498
Zebrafish
positive regulation of map kinase activity GO:0043406 3 0.497
cellular component morphogenesis GO:0032989 336 0.492
Zebrafish
cell projection assembly GO:0030031 64 0.469
Zebrafish
camera type eye morphogenesis GO:0048593 108 0.462
chordate embryonic development GO:0043009 271 0.461
establishment or maintenance of monopolar cell polarity GO:0061339 2 0.457
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.447
Zebrafish
cell morphogenesis GO:0000902 289 0.443
Zebrafish
establishment of apical basal cell polarity GO:0035089 2 0.437
axis elongation involved in somitogenesis GO:0090245 2 0.432
regulation of cell matrix adhesion GO:0001952 1 0.428
eye photoreceptor cell differentiation GO:0001754 45 0.425
Zebrafish
central nervous system development GO:0007417 387 0.414
positive regulation of cell matrix adhesion GO:0001954 1 0.406
establishment of mitotic spindle orientation GO:0000132 10 0.400
regulation of cell substrate adhesion GO:0010810 1 0.385
stem cell development GO:0048864 82 0.383
inner ear development GO:0048839 126 0.383
regulation of cell differentiation GO:0045595 142 0.379
organelle organization GO:0006996 227 0.372
Zebrafish
establishment of cell polarity GO:0030010 18 0.367
establishment of spindle localization GO:0051293 12 0.355
tissue homeostasis GO:0001894 25 0.349
cell projection morphogenesis GO:0048858 244 0.347
Zebrafish
nonmotile primary cilium assembly GO:0035058 2 0.346
eye photoreceptor cell development GO:0042462 30 0.337
Zebrafish
cellular macromolecule metabolic process GO:0044260 391 0.331
neurological system process GO:0050877 62 0.329
tissue migration GO:0090130 37 0.328
establishment of epithelial cell apical basal polarity GO:0045198 2 0.323
hindbrain development GO:0030902 91 0.320
urogenital system development GO:0001655 97 0.306
Zebrafish
retina layer formation GO:0010842 24 0.306
photoreceptor cell development GO:0042461 40 0.306
Zebrafish
ribonucleoside monophosphate catabolic process GO:0009158 4 0.304
renal system development GO:0072001 94 0.299
Zebrafish
cellular component movement GO:0006928 335 0.297
establishment of mitotic spindle localization GO:0040001 12 0.296
stem cell differentiation GO:0048863 117 0.292
morphogenesis of an epithelium GO:0002009 333 0.291
canonical wnt signaling pathway GO:0060070 48 0.288
Zebrafish
purine containing compound metabolic process GO:0072521 29 0.286
pronephros development GO:0048793 69 0.284
Zebrafish
brain development GO:0007420 293 0.281
muscle structure development GO:0061061 196 0.273
developmental pigmentation GO:0048066 48 0.273
immune system development GO:0002520 191 0.273
regulation of neurotransmitter transport GO:0051588 1 0.270
larval development GO:0002164 2 0.268
regulation of neuron differentiation GO:0045664 56 0.266
cell substrate adhesion GO:0031589 4 0.265
regulation of cellular metabolic process GO:0031323 320 0.255
protein localization GO:0008104 40 0.250
positive regulation of glial cell proliferation GO:0060252 1 0.245
polarized epithelial cell differentiation GO:0030859 4 0.243
regulation of biological quality GO:0065008 263 0.239
regulation of canonical wnt signaling pathway GO:0060828 34 0.233
Zebrafish
autophagy GO:0006914 4 0.232
mitotic cell cycle process GO:1903047 48 0.229
regulation of cell projection assembly GO:0060491 4 0.228
regulation of multicellular organismal process GO:0051239 277 0.224
notch signaling pathway GO:0007219 35 0.224
mesenchymal cell development GO:0014031 78 0.221
hematopoietic or lymphoid organ development GO:0048534 191 0.219
positive regulation of gliogenesis GO:0014015 2 0.218
ameboidal type cell migration GO:0001667 143 0.217
nucleoside monophosphate catabolic process GO:0009125 4 0.216
adherens junction organization GO:0034332 4 0.209
regulation of axonogenesis GO:0050770 32 0.209
neuron projection morphogenesis GO:0048812 161 0.208
cell matrix adhesion GO:0007160 4 0.204
axial mesoderm morphogenesis GO:0048319 8 0.203
axon ensheathment GO:0008366 18 0.201
sensory perception of light stimulus GO:0050953 19 0.199
regulation of multicellular organismal development GO:2000026 223 0.199
visual perception GO:0007601 17 0.198
pigment cell differentiation GO:0050931 38 0.189
regulation of meiotic cell cycle GO:0051445 1 0.189
cell substrate adherens junction assembly GO:0007045 1 0.180
glomerulus development GO:0032835 27 0.179
Zebrafish
cellular component biogenesis GO:0044085 178 0.178
Zebrafish
kidney development GO:0001822 92 0.174
Zebrafish
nuclear migration GO:0007097 3 0.169
auditory receptor cell differentiation GO:0042491 15 0.165
mesodermal cell migration GO:0008078 12 0.164
purine nucleoside monophosphate catabolic process GO:0009128 4 0.164
cardiac atrium morphogenesis GO:0003209 2 0.163
regulation of neurogenesis GO:0050767 87 0.160
positive regulation of cell adhesion GO:0045785 1 0.159
epidermis development GO:0008544 48 0.159
epithelial cell migration GO:0010631 25 0.157
hemopoiesis GO:0030097 183 0.157
developmental growth involved in morphogenesis GO:0060560 86 0.156
positive regulation of notch signaling pathway GO:0045747 3 0.155
single fertilization GO:0007338 3 0.154
positive regulation of catalytic activity GO:0043085 25 0.154
smoothened signaling pathway GO:0007224 30 0.148
positive regulation of cell fate specification GO:0042660 1 0.146
myelination in peripheral nervous system GO:0022011 4 0.145
positive regulation of stem cell proliferation GO:2000648 1 0.144
epithelial cell morphogenesis GO:0003382 2 0.143
swim bladder development GO:0048794 19 0.140
Zebrafish
mesenchyme development GO:0060485 127 0.137
positive regulation of response to stimulus GO:0048584 80 0.137
regulation of oligodendrocyte differentiation GO:0048713 1 0.136
cell adhesion GO:0007155 40 0.136
embryonic epithelial tube formation GO:0001838 17 0.135
pigment granule localization GO:0051875 25 0.134
regulation of signaling GO:0023051 235 0.133
regulation of primary metabolic process GO:0080090 311 0.129
skin development GO:0043588 54 0.127
digestive tract mesoderm development GO:0007502 1 0.127
regulation of glial cell proliferation GO:0060251 4 0.126
detection of abiotic stimulus GO:0009582 24 0.126
response to chemical GO:0042221 320 0.126
spindle localization GO:0051653 12 0.124
fertilization GO:0009566 3 0.122
regulation of response to stimulus GO:0048583 269 0.121
head development GO:0060322 303 0.121
establishment of localization GO:0051234 244 0.120
neural retina development GO:0003407 49 0.117
mitotic cell cycle GO:0000278 64 0.117
neural plate development GO:0001840 10 0.116
phosphorus metabolic process GO:0006793 109 0.114
neural tube development GO:0021915 62 0.113
regulation of production of molecular mediator of immune response GO:0002700 1 0.113
embryonic hemopoiesis GO:0035162 53 0.113
neuroepithelial cell differentiation GO:0060563 26 0.112
ear development GO:0043583 127 0.112
ensheathment of neurons GO:0007272 18 0.111
neuron projection development GO:0031175 180 0.110
glial cell differentiation GO:0010001 42 0.110
regulation of cell projection organization GO:0031344 44 0.110
cilium assembly GO:0042384 58 0.110
Zebrafish
regulation of neurotransmitter secretion GO:0046928 1 0.108
organelle assembly GO:0070925 110 0.107
Zebrafish
regionalization GO:0003002 274 0.106
cellular component disassembly GO:0022411 1 0.105
ribose phosphate metabolic process GO:0019693 27 0.104
regulation of cell communication GO:0010646 232 0.104
positive regulation of glucose transport GO:0010828 1 0.103
cellular response to external stimulus GO:0071496 2 0.103
homeostatic process GO:0042592 142 0.103
mesenchymal cell differentiation GO:0048762 87 0.101
rhombomere morphogenesis GO:0021593 17 0.101
glial cell fate determination GO:0007403 1 0.101
response to drug GO:0042493 3 0.099
anion transmembrane transport GO:0098656 12 0.099
ion transport GO:0006811 114 0.098
cell morphogenesis involved in differentiation GO:0000904 195 0.096
cellular localization GO:0051641 97 0.096
aging GO:0007568 2 0.096
morphogenesis of embryonic epithelium GO:0016331 30 0.095
regulation of metabolic process GO:0019222 359 0.095
transport GO:0006810 220 0.093
floor plate development GO:0033504 15 0.093
glial cell proliferation GO:0014009 4 0.092
protein modification process GO:0036211 100 0.091
axonogenesis GO:0007409 152 0.090
auditory receptor cell fate commitment GO:0009912 4 0.090
ion transmembrane transport GO:0034220 91 0.088
nucleobase containing small molecule metabolic process GO:0055086 32 0.088
synaptic transmission GO:0007268 35 0.087
embryonic skeletal system development GO:0048706 97 0.087
death GO:0016265 121 0.086
negative regulation of histone methylation GO:0031061 1 0.085
embryonic organ development GO:0048568 381 0.085
transmembrane transport GO:0055085 120 0.084
establishment of organelle localization GO:0051656 45 0.084
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.083
regulation of glucose transport GO:0010827 1 0.083
retinal pigment epithelium development GO:0003406 8 0.082
regulation of skeletal muscle fiber development GO:0048742 2 0.082
response to abiotic stimulus GO:0009628 122 0.080
atp catabolic process GO:0006200 4 0.080
cell cell junction organization GO:0045216 10 0.079
protein metabolic process GO:0019538 183 0.079
chloride transmembrane transport GO:1902476 4 0.079
immune system process GO:0002376 241 0.078
tube formation GO:0035148 25 0.078
regulation of epithelial to mesenchymal transition GO:0010717 3 0.078
sensory perception GO:0007600 39 0.078
renal filtration GO:0097205 10 0.077
Zebrafish
regulation of multicellular organism growth GO:0040014 4 0.077
epithelial cell differentiation GO:0030855 116 0.076
response to external stimulus GO:0009605 264 0.076
multicellular organism growth GO:0035264 4 0.076
negative regulation of biological process GO:0048519 304 0.076
peripheral nervous system development GO:0007422 55 0.075
regulation of leukocyte mediated immunity GO:0002703 1 0.073
detection of visible light GO:0009584 12 0.073
cellular response to light stimulus GO:0071482 4 0.073
leukocyte homeostasis GO:0001776 2 0.072
developmental growth GO:0048589 166 0.072
embryonic heart tube development GO:0035050 133 0.071
melanocyte differentiation GO:0030318 26 0.071
cell cycle GO:0007049 93 0.070
cellular nitrogen compound metabolic process GO:0034641 290 0.069
establishment of localization in cell GO:0051649 77 0.069
vasculature development GO:0001944 278 0.069
developmental programmed cell death GO:0010623 4 0.069
camera type eye photoreceptor cell differentiation GO:0060219 19 0.069
heart morphogenesis GO:0003007 156 0.068
calcium ion transport GO:0006816 18 0.068
calcium ion dependent exocytosis GO:0017156 1 0.067
gliogenesis GO:0042063 45 0.066
neurotransmitter secretion GO:0007269 2 0.065
endocardium morphogenesis GO:0003160 4 0.065
homeostasis of number of cells within a tissue GO:0048873 4 0.065
positive regulation of cell differentiation GO:0045597 30 0.065
positive regulation of epithelial cell differentiation GO:0030858 2 0.064
positive regulation of cell communication GO:0010647 56 0.064
regulation of signal transduction GO:0009966 225 0.063
organ regeneration GO:0031100 1 0.063
single organism localization GO:1902578 225 0.063
cell fate commitment GO:0045165 99 0.063
regulation of retina development in camera type eye GO:1902866 2 0.062
adult behavior GO:0030534 2 0.061
single organismal cell cell adhesion GO:0016337 29 0.061
positive regulation of signal transduction GO:0009967 56 0.061
cation transport GO:0006812 81 0.061
cell junction organization GO:0034330 11 0.061
regulation of filopodium assembly GO:0051489 2 0.061
regulation of calcium ion dependent exocytosis GO:0017158 1 0.060
cell cell adhesion GO:0098609 6 0.060
muscle cell differentiation GO:0042692 139 0.060
regulation of autophagy GO:0010506 3 0.059
regulation of organ growth GO:0046620 3 0.059
ventral spinal cord interneuron specification GO:0021521 3 0.059
regulation of membrane potential GO:0042391 23 0.059
regulation of calcium ion transport GO:0051924 2 0.058
appendage development GO:0048736 80 0.058
neuroblast proliferation GO:0007405 2 0.057
neuron neuron synaptic transmission GO:0007270 1 0.057
positive regulation of cell substrate adhesion GO:0010811 1 0.057
oligodendrocyte cell fate specification GO:0021778 4 0.057
extrinsic apoptotic signaling pathway GO:0097191 3 0.057
keratinocyte differentiation GO:0030216 0 0.057
positive regulation of signaling GO:0023056 56 0.056
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.056
regulation of stem cell differentiation GO:2000736 4 0.056
immunoglobulin mediated immune response GO:0016064 3 0.056
regulation of cell development GO:0060284 100 0.056
melanosome transport GO:0032402 19 0.056
protein complex localization GO:0031503 1 0.055
neural crest cell migration GO:0001755 42 0.055
cellular response to prostaglandin stimulus GO:0071379 3 0.055
regulation of developmental process GO:0050793 247 0.055
endosomal transport GO:0016197 2 0.055
regulation of cell adhesion GO:0030155 15 0.054
sensory system development GO:0048880 76 0.054
embryonic skeletal system morphogenesis GO:0048704 93 0.054
purine ribonucleotide metabolic process GO:0009150 27 0.053
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.053
regulation of organ morphogenesis GO:2000027 35 0.053
myeloid cell homeostasis GO:0002262 56 0.053
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.053
mechanoreceptor differentiation GO:0042490 37 0.052
multicellular organismal signaling GO:0035637 22 0.052
regulation of notch signaling pathway GO:0008593 16 0.052
positive regulation of neural precursor cell proliferation GO:2000179 1 0.051
negative regulation of notch signaling pathway GO:0045746 6 0.051
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.051
somitogenesis GO:0001756 87 0.051
schwann cell differentiation GO:0014037 9 0.050
neuronal action potential GO:0019228 18 0.050
rna 3 end processing GO:0031123 2 0.050
regulation of eye photoreceptor cell development GO:0042478 2 0.050
positive regulation of epithelial cell migration GO:0010634 2 0.049
inner ear receptor cell fate commitment GO:0060120 4 0.049
homeostasis of number of cells GO:0048872 62 0.048
regulation of cellular amino acid metabolic process GO:0006521 0 0.048
production of molecular mediator of immune response GO:0002440 2 0.048
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.048
embryonic limb morphogenesis GO:0030326 2 0.048
regulation of neuron projection development GO:0010975 40 0.047
membrane hyperpolarization GO:0060081 1 0.047
cardiac muscle cell contraction GO:0086003 1 0.047
heart development GO:0007507 313 0.046
regulation of cellular component organization GO:0051128 86 0.046
establishment of vesicle localization GO:0051650 24 0.045
positive regulation of glial cell differentiation GO:0045687 1 0.044
glomerulus vasculature development GO:0072012 2 0.044
multicellular organismal homeostasis GO:0048871 29 0.044
histone h3 k4 methylation GO:0051568 2 0.044
cell cell adhesion involved in mesendodermal cell migration GO:0003370 1 0.044
blood vessel endothelial cell migration GO:0043534 18 0.044
regulation of apoptotic process GO:0042981 98 0.043
exocytosis GO:0006887 1 0.043
macromolecule localization GO:0033036 54 0.043
epithelial tube morphogenesis GO:0060562 148 0.043
muscle cell development GO:0055001 115 0.043
sodium ion transmembrane transport GO:0035725 21 0.043
muscle organ morphogenesis GO:0048644 8 0.043
macromolecule modification GO:0043412 111 0.042
negative regulation of protein kinase activity GO:0006469 4 0.042
mrna 3 end processing GO:0031124 2 0.042
regulation of dendrite development GO:0050773 3 0.042
regulation of dendrite morphogenesis GO:0048814 3 0.042
neurotransmitter transport GO:0006836 2 0.042
venous blood vessel morphogenesis GO:0048845 3 0.042
epidermal cell differentiation GO:0009913 36 0.041
tube morphogenesis GO:0035239 349 0.041
cell motility GO:0048870 244 0.041
adherens junction maintenance GO:0034334 2 0.041
heterocycle biosynthetic process GO:0018130 215 0.041
rhombomere development GO:0021546 19 0.041
cardiac conduction system development GO:0003161 1 0.040
regulation of nucleoside metabolic process GO:0009118 2 0.040
myelin assembly GO:0032288 1 0.040
cranial nerve development GO:0021545 42 0.040
maintenance of blood brain barrier GO:0035633 1 0.040
positive regulation of cellular catabolic process GO:0031331 3 0.040
regulation of cellular ketone metabolic process GO:0010565 7 0.040
cellular component assembly involved in morphogenesis GO:0010927 107 0.039
Zebrafish
kidney vasculature development GO:0061440 2 0.039
detection of stimulus GO:0051606 29 0.039
receptor recycling GO:0001881 4 0.039
regulation of macromolecule metabolic process GO:0060255 317 0.039
multi organism cellular process GO:0044764 2 0.039
action potential GO:0001508 19 0.039
organonitrogen compound metabolic process GO:1901564 74 0.038
epithelial tube formation GO:0072175 19 0.038
epithelium migration GO:0090132 25 0.038
negative regulation of epithelial cell migration GO:0010633 1 0.038
positive regulation of mesodermal cell fate specification GO:0048337 1 0.038
regulation of sequestering of calcium ion GO:0051282 4 0.038
cell surface receptor signaling pathway GO:0007166 325 0.038
inorganic anion transport GO:0015698 25 0.037
cell substrate junction assembly GO:0007044 2 0.037
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.037
schwann cell development GO:0014044 9 0.036
telomere organization GO:0032200 1 0.036
neural crest cell differentiation GO:0014033 72 0.036
cell cell junction maintenance GO:0045217 1 0.036
morphogenesis of an epithelial sheet GO:0002011 49 0.036
proximal tubule development GO:0072014 3 0.036
adherens junction assembly GO:0034333 1 0.036
desmosome assembly GO:0002159 2 0.035
rhombomere boundary formation GO:0021654 10 0.035
positive regulation of cellular component biogenesis GO:0044089 3 0.035
pronuclear migration GO:0035046 1 0.035
positive regulation of endothelial cell differentiation GO:0045603 2 0.035
calcium mediated signaling GO:0019722 2 0.035
regulation of cell growth GO:0001558 29 0.035
single organism cell adhesion GO:0098602 29 0.035
single organism transport GO:0044765 206 0.035
growth GO:0040007 174 0.035
positive regulation of cell development GO:0010720 25 0.034
central nervous system neuron differentiation GO:0021953 74 0.034
neural crest cell development GO:0014032 62 0.034
nucleotide metabolic process GO:0009117 28 0.034
maintenance of location GO:0051235 4 0.034
locomotion GO:0040011 313 0.034
regulation of collateral sprouting in absence of injury GO:0048696 4 0.034
regulation of mrna catabolic process GO:0061013 3 0.033
lateral line system development GO:0048925 76 0.033
regulation of metal ion transport GO:0010959 4 0.033
peptidyl serine phosphorylation GO:0018105 1 0.033
embryonic organ morphogenesis GO:0048562 274 0.033
negative regulation of glial cell proliferation GO:0060253 1 0.033
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.033
actin mediated cell contraction GO:0070252 1 0.033
somite development GO:0061053 96 0.033
regulation of epidermis development GO:0045682 2 0.033
muscle fiber development GO:0048747 52 0.033
nucleic acid metabolic process GO:0090304 244 0.033
heart looping GO:0001947 94 0.033
regulation of glial cell differentiation GO:0045685 4 0.033
regulation of inflammatory response GO:0050727 2 0.033
nuclear division GO:0000280 23 0.033
retinal cone cell development GO:0046549 8 0.032
regulation of cell shape GO:0008360 1 0.032
g1 s transition of mitotic cell cycle GO:0000082 1 0.032
mitotic nuclear division GO:0007067 18 0.032
protein secretion GO:0009306 1 0.031
stem cell proliferation GO:0072089 4 0.031
leukocyte proliferation GO:0070661 1 0.031
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.031
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 6 0.030
cellular response to growth factor stimulus GO:0071363 39 0.030
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.030
regulation of programmed cell death GO:0043067 101 0.030
positive regulation of cell death GO:0010942 29 0.030
ventral spinal cord interneuron fate commitment GO:0060579 3 0.030
protein localization to microtubule cytoskeleton GO:0072698 1 0.030
transmission of nerve impulse GO:0019226 19 0.030
positive regulation of stress activated mapk cascade GO:0032874 3 0.029
regulation of cellular amine metabolic process GO:0033238 0 0.029
regulation of axon extension GO:0030516 24 0.029
embryonic eye morphogenesis GO:0048048 30 0.029
regeneration GO:0031099 91 0.029
muscle contraction GO:0006936 18 0.029
immunoglobulin production GO:0002377 1 0.029
g2 dna damage checkpoint GO:0031572 3 0.029
cellular protein metabolic process GO:0044267 129 0.029
regulation of mrna processing GO:0050684 3 0.029
small molecule metabolic process GO:0044281 77 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.029
auditory receptor cell morphogenesis GO:0002093 4 0.029
nuclear pore organization GO:0006999 2 0.028
regulation of phosphate metabolic process GO:0019220 43 0.028
unidimensional cell growth GO:0009826 5 0.028
hematopoietic stem cell differentiation GO:0060218 20 0.028
basement membrane assembly GO:0070831 3 0.028
axon ensheathment in central nervous system GO:0032291 2 0.028
nerve development GO:0021675 45 0.028
angiogenesis GO:0001525 158 0.028
interspecies interaction between organisms GO:0044419 4 0.028
negative regulation of autophagy GO:0010507 1 0.028
commissural neuron axon guidance GO:0071679 3 0.028
regulation of anatomical structure morphogenesis GO:0022603 130 0.028
axon guidance GO:0007411 86 0.027
actin filament based process GO:0030029 64 0.027
embryonic appendage morphogenesis GO:0035113 30 0.027
striated muscle tissue development GO:0014706 110 0.027
pericardium morphogenesis GO:0003344 1 0.027
glomerular filtration GO:0003094 6 0.027
Zebrafish
cardiac atrium development GO:0003230 4 0.027
organic cyclic compound metabolic process GO:1901360 301 0.027
b cell mediated immunity GO:0019724 3 0.027
regulation of protein phosphorylation GO:0001932 18 0.027
positive regulation of cellular process GO:0048522 201 0.027
striated muscle cell development GO:0055002 108 0.026
renal system vasculature development GO:0061437 2 0.026
cell cycle process GO:0022402 53 0.026
heart contraction GO:0060047 71 0.026
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.026
cellular pigmentation GO:0033059 30 0.026
lamellipodium assembly GO:0030032 1 0.026
positive regulation of developmental process GO:0051094 50 0.026
leukocyte differentiation GO:0002521 25 0.026
regulation of nitrogen compound metabolic process GO:0051171 251 0.026
positive regulation of neuron death GO:1901216 1 0.025
hair cell differentiation GO:0035315 32 0.025
inner ear receptor stereocilium organization GO:0060122 8 0.025
positive regulation of transport GO:0051050 2 0.025
anatomical structure homeostasis GO:0060249 36 0.025
negative regulation of programmed cell death GO:0043069 58 0.025
reactive nitrogen species metabolic process GO:2001057 0 0.025
mitochondrion organization GO:0007005 4 0.025
cellular response to nutrient levels GO:0031669 2 0.024
regulation of epithelial cell migration GO:0010632 5 0.024
embryonic viscerocranium morphogenesis GO:0048703 52 0.024
cell division GO:0051301 20 0.024

crb2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.147
disease of anatomical entity DOID:7 0 0.147
eye and adnexa disease DOID:1492 0 0.147
nervous system disease DOID:863 0 0.147
eye disease DOID:5614 0 0.147
retinal disease DOID:5679 0 0.097
cancer DOID:162 0 0.036
disease of cellular proliferation DOID:14566 0 0.036
organ system cancer DOID:0050686 0 0.036