Danio rerio

0 known processes

crb3b

crumbs homolog 3b

crb3b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.585
hair cell differentiation GO:0035315 32 0.415
head development GO:0060322 303 0.406
apical protein localization GO:0045176 6 0.392
establishment or maintenance of bipolar cell polarity GO:0061245 12 0.310
asymmetric protein localization GO:0008105 6 0.268
brain development GO:0007420 293 0.254
sensory organ development GO:0007423 393 0.208
renal filtration GO:0097205 10 0.196
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.192
retina morphogenesis in camera type eye GO:0060042 79 0.191
glomerulus development GO:0032835 27 0.185
detection of visible light GO:0009584 12 0.178
regulation of cell communication GO:0010646 232 0.174
cell projection organization GO:0030030 284 0.172
neuron differentiation GO:0030182 353 0.171
signal transduction GO:0007165 455 0.152
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.150
kidney development GO:0001822 92 0.146
generation of neurons GO:0048699 385 0.136
wnt signaling pathway GO:0016055 80 0.135
regulation of signal transduction GO:0009966 225 0.135
single organism transport GO:0044765 206 0.132
establishment or maintenance of apical basal cell polarity GO:0035088 12 0.130
cilium organization GO:0044782 71 0.128
neuron development GO:0048666 262 0.125
cellular response to radiation GO:0071478 4 0.120
negative regulation of signaling GO:0023057 96 0.118
detection of abiotic stimulus GO:0009582 24 0.114
nephron development GO:0072006 31 0.111
glomerular filtration GO:0003094 6 0.100
medulla oblongata development GO:0021550 4 0.099
eye development GO:0001654 277 0.098
single organism organelle organization GO:1902589 199 0.097
eye photoreceptor cell development GO:0042462 30 0.097
cognition GO:0050890 1 0.093
regulation of binding GO:0051098 3 0.091
morphogenesis of an epithelium GO:0002009 333 0.091
digestive tract morphogenesis GO:0048546 231 0.087
cilium assembly GO:0042384 58 0.086
cell surface receptor signaling pathway GO:0007166 325 0.085
hindbrain development GO:0030902 91 0.085
response to abiotic stimulus GO:0009628 122 0.083
system process GO:0003008 185 0.082
cellular response to external stimulus GO:0071496 2 0.079
regulation of primary metabolic process GO:0080090 311 0.078
negative regulation of biological process GO:0048519 304 0.076
urogenital system development GO:0001655 97 0.075
phototransduction GO:0007602 2 0.074
cellular macromolecule metabolic process GO:0044260 391 0.073
smooth muscle contraction GO:0006939 2 0.071
cell projection morphogenesis GO:0048858 244 0.068
visual perception GO:0007601 17 0.068
ear development GO:0043583 127 0.067
cellular component assembly involved in morphogenesis GO:0010927 107 0.067
eye morphogenesis GO:0048592 144 0.067
cilium morphogenesis GO:0060271 85 0.067
skin development GO:0043588 54 0.066
single organismal cell cell adhesion GO:0016337 29 0.064
regulation of canonical wnt signaling pathway GO:0060828 34 0.064
cellular component biogenesis GO:0044085 178 0.063
cell projection assembly GO:0030031 64 0.062
neurological system process GO:0050877 62 0.061
regulation of biological quality GO:0065008 263 0.061
canonical wnt signaling pathway GO:0060070 48 0.060
single organism cell adhesion GO:0098602 29 0.060
negative regulation of notch signaling pathway GO:0045746 6 0.059
response to monosaccharide GO:0034284 3 0.058
regulation of muscle contraction GO:0006937 3 0.057
cellular response to light stimulus GO:0071482 4 0.056
regulation of guanylate cyclase activity GO:0031282 6 0.056
negative regulation of cellular process GO:0048523 283 0.055
regulation of wnt signaling pathway GO:0030111 53 0.055
response to drug GO:0042493 3 0.054
neural nucleus development GO:0048857 15 0.054
response to transition metal nanoparticle GO:1990267 28 0.053
inner ear development GO:0048839 126 0.052
digestive system development GO:0055123 289 0.052
establishment of localization GO:0051234 244 0.051
response to metal ion GO:0010038 34 0.051
regulation of blood vessel size GO:0050880 2 0.050
adult behavior GO:0030534 2 0.049
regulation of macromolecule metabolic process GO:0060255 317 0.049
positive regulation of cellular process GO:0048522 201 0.047
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.046
regulation of signaling GO:0023051 235 0.046
cell morphogenesis GO:0000902 289 0.046
maintenance of location GO:0051235 4 0.044
negative regulation of response to stimulus GO:0048585 104 0.043
regulation of inflammatory response GO:0050727 2 0.043
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.042
positive regulation of cellular component biogenesis GO:0044089 3 0.041
organelle assembly GO:0070925 110 0.041
positive regulation of transport GO:0051050 2 0.041
response to vitamin GO:0033273 3 0.040
cell motility GO:0048870 244 0.040
mechanoreceptor differentiation GO:0042490 37 0.039
epidermis development GO:0008544 48 0.038
regulation of tube size GO:0035150 2 0.038
retina development in camera type eye GO:0060041 146 0.038
central nervous system development GO:0007417 387 0.037
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.037
renal system development GO:0072001 94 0.035
cell cell adhesion GO:0098609 6 0.035
multicellular organism growth GO:0035264 4 0.035
peptide transport GO:0015833 1 0.034
negative regulation of cell communication GO:0010648 96 0.034
cation transmembrane transport GO:0098655 65 0.033
multicellular organismal homeostasis GO:0048871 29 0.033
cell migration GO:0016477 237 0.033
phototransduction visible light GO:0007603 2 0.033
positive regulation of glucose transport GO:0010828 1 0.032
positive regulation of catabolic process GO:0009896 4 0.032
protein complex localization GO:0031503 1 0.032
small molecule metabolic process GO:0044281 77 0.032
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 11 0.032
homeostasis of number of cells within a tissue GO:0048873 4 0.032
regulation of protein complex assembly GO:0043254 3 0.031
regulation of response to stimulus GO:0048583 269 0.031
positive regulation of cell cycle GO:0045787 3 0.031
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
regulation of stem cell differentiation GO:2000736 4 0.031
regulation of cellular metabolic process GO:0031323 320 0.031
regulation of establishment of protein localization GO:0070201 4 0.031
establishment or maintenance of cell polarity GO:0007163 29 0.031
aging GO:0007568 2 0.030
adherens junction organization GO:0034332 4 0.030
reactive oxygen species biosynthetic process GO:1903409 1 0.029
monoamine transport GO:0015844 1 0.029
camera type eye development GO:0043010 222 0.028
i kappab kinase nf kappab signaling GO:0007249 4 0.028
multicellular organismal signaling GO:0035637 22 0.028
cellular component morphogenesis GO:0032989 336 0.028
positive regulation of blood circulation GO:1903524 2 0.028
g protein coupled receptor signaling pathway GO:0007186 74 0.028
positive regulation of cell adhesion GO:0045785 1 0.028
cellular response to nutrient levels GO:0031669 2 0.028
ion transport GO:0006811 114 0.028
heterocycle metabolic process GO:0046483 290 0.028
response to inorganic substance GO:0010035 38 0.028
phosphorus metabolic process GO:0006793 109 0.028
exocytosis GO:0006887 1 0.027
protein polymerization GO:0051258 4 0.027
organic anion transport GO:0015711 15 0.027
maintenance of epithelial cell apical basal polarity GO:0045199 5 0.026
sensory perception of light stimulus GO:0050953 19 0.026
protein localization GO:0008104 40 0.026
regulation of protein binding GO:0043393 3 0.026
transmembrane transport GO:0055085 120 0.026
cellular component movement GO:0006928 335 0.026
regulation of carbohydrate metabolic process GO:0006109 4 0.026
hormone transport GO:0009914 2 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.025
cellular response to extracellular stimulus GO:0031668 2 0.025
establishment of synaptic vesicle localization GO:0097480 1 0.025
positive regulation of cellular catabolic process GO:0031331 3 0.025
positive regulation of protein complex assembly GO:0031334 2 0.025
regulation of metal ion transport GO:0010959 4 0.024
cell substrate adherens junction assembly GO:0007045 1 0.024
response to organic substance GO:0010033 153 0.024
regulation of glucose import GO:0046324 1 0.024
protein metabolic process GO:0019538 183 0.024
apoptotic process GO:0006915 116 0.024
inner ear receptor cell differentiation GO:0060113 29 0.024
eye photoreceptor cell differentiation GO:0001754 45 0.024
regulation of metabolic process GO:0019222 359 0.024
single organism nuclear import GO:1902593 3 0.024
sensory organ morphogenesis GO:0090596 200 0.024
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
cellular carbohydrate metabolic process GO:0044262 4 0.023
cellular component disassembly GO:0022411 1 0.023
regulation of cytokine production GO:0001817 3 0.022
response to hexose GO:0009746 3 0.022
pronephros development GO:0048793 69 0.022
sensory perception GO:0007600 39 0.022
nucleocytoplasmic transport GO:0006913 4 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
liver development GO:0001889 96 0.021
nitrogen compound metabolic process GO:0006807 319 0.021
inorganic cation transmembrane transport GO:0098662 50 0.021
actin polymerization or depolymerization GO:0008154 2 0.021
regulation of protein polymerization GO:0032271 2 0.021
positive regulation of secretion by cell GO:1903532 1 0.021
regulation of hormone secretion GO:0046883 2 0.021
axon ensheathment GO:0008366 18 0.021
autophagy GO:0006914 4 0.021
response to external stimulus GO:0009605 264 0.021
actin filament based movement GO:0030048 1 0.021
notch signaling pathway GO:0007219 35 0.021
protein secretion GO:0009306 1 0.020
regulation of protein targeting GO:1903533 2 0.020
photoreceptor cell development GO:0042461 40 0.020
smoothened signaling pathway GO:0007224 30 0.020
polarized epithelial cell differentiation GO:0030859 4 0.020
organelle organization GO:0006996 227 0.020
response to uv GO:0009411 3 0.020
response to carbohydrate GO:0009743 3 0.020
circadian sleep wake cycle sleep GO:0050802 1 0.020
protein import GO:0017038 3 0.020
muscle structure development GO:0061061 196 0.019
bicarbonate transport GO:0015701 4 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
single organism metabolic process GO:0044710 217 0.019
regulation of mrna processing GO:0050684 3 0.019
angiogenesis GO:0001525 158 0.019
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.019
regulation of blood pressure GO:0008217 1 0.019
muscle cell development GO:0055001 115 0.019
cellular nitrogen compound metabolic process GO:0034641 290 0.019
regulation of multicellular organism growth GO:0040014 4 0.019
transport GO:0006810 220 0.019
protein import into nucleus GO:0006606 3 0.019
carbohydrate derivative biosynthetic process GO:1901137 43 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
blood circulation GO:0008015 87 0.019
fatty acid transport GO:0015908 1 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
cellular component assembly GO:0022607 170 0.018
regulation of protein localization to nucleus GO:1900180 2 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
cellular aromatic compound metabolic process GO:0006725 295 0.018
larval development GO:0002164 2 0.018
compound eye development GO:0048749 2 0.018
gtp catabolic process GO:0006184 2 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
ameboidal type cell migration GO:0001667 143 0.018
response to light stimulus GO:0009416 46 0.018
regulation of autophagy GO:0010506 3 0.018
ion transmembrane transport GO:0034220 91 0.018
sodium ion import GO:0097369 3 0.018
cellular response to decreased oxygen levels GO:0036294 1 0.018
macromolecule modification GO:0043412 111 0.018
regulation of protein transport GO:0051223 3 0.018
gas transport GO:0015669 3 0.017
mitotic cell cycle GO:0000278 64 0.017
negative regulation of signal transduction GO:0009968 94 0.017
muscle contraction GO:0006936 18 0.017
chordate embryonic development GO:0043009 271 0.017
single organism localization GO:1902578 225 0.017
leukocyte proliferation GO:0070661 1 0.017
nuclear migration GO:0007097 3 0.017
programmed cell death GO:0012501 119 0.017
circulatory system process GO:0003013 87 0.017
muscle cell differentiation GO:0042692 139 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
vasculature development GO:0001944 278 0.017
positive regulation of protein polymerization GO:0032273 2 0.017
synaptic vesicle localization GO:0097479 1 0.017
amino acid transport GO:0006865 2 0.017
cellular biosynthetic process GO:0044249 286 0.017
cellular response to hypoxia GO:0071456 1 0.017
regulation of protein import into nucleus GO:0042306 2 0.016
cytokinesis GO:0000910 3 0.016
regulation of protein catabolic process GO:0042176 1 0.016
homeostatic process GO:0042592 142 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
cellular response to oxygen levels GO:0071453 1 0.016
regulation of circadian rhythm GO:0042752 4 0.016
protein complex disassembly GO:0043241 1 0.016
positive regulation of cytokine production GO:0001819 2 0.016
multi organism cellular process GO:0044764 2 0.016
amide transport GO:0042886 12 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
positive regulation of biological process GO:0048518 253 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
regulation of neurotransmitter transport GO:0051588 1 0.016
membrane fusion GO:0061025 2 0.016
establishment of localization in cell GO:0051649 77 0.016
mitotic cell cycle process GO:1903047 48 0.015
energy reserve metabolic process GO:0006112 2 0.015
carbon dioxide transport GO:0015670 3 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
regulation of cell differentiation GO:0045595 142 0.015
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
response to stress GO:0006950 263 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
auditory receptor cell differentiation GO:0042491 15 0.015
immune system process GO:0002376 241 0.015
regulation of gene expression GO:0010468 265 0.015
glucose import GO:0046323 2 0.015
blood vessel development GO:0001568 246 0.015
negative regulation of wnt signaling pathway GO:0030178 30 0.015
protein localization to nucleus GO:0034504 3 0.015
localization of cell GO:0051674 244 0.015
biological adhesion GO:0022610 40 0.015
cellular response to methanol GO:0071405 4 0.015
locomotion GO:0040011 313 0.014
regulation of cell activation GO:0050865 1 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
behavior GO:0007610 74 0.014
embryonic heart tube development GO:0035050 133 0.014
amine metabolic process GO:0009308 2 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
response to chemical GO:0042221 320 0.014
regulation of developmental process GO:0050793 247 0.014
detection of stimulus GO:0051606 29 0.014
positive regulation of inflammatory response GO:0050729 1 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
epithelial cell differentiation GO:0030855 116 0.014
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
gene expression GO:0010467 252 0.014
regulation of programmed cell death GO:0043067 101 0.014
positive regulation of glucose import GO:0046326 1 0.014
macromolecular complex disassembly GO:0032984 1 0.014
camera type eye morphogenesis GO:0048593 108 0.014
regulation of glucose transport GO:0010827 1 0.014
sleep GO:0030431 1 0.014
response to methanol GO:0033986 4 0.014
photoreceptor cell differentiation GO:0046530 55 0.014
biosynthetic process GO:0009058 294 0.014
cellular amine metabolic process GO:0044106 2 0.013
response to glucocorticoid GO:0051384 1 0.013
regulation of calcium ion transport GO:0051924 2 0.013
tissue homeostasis GO:0001894 25 0.013
nuclear import GO:0051170 3 0.013
negative regulation of apoptotic process GO:0043066 55 0.013
cell adhesion GO:0007155 40 0.013
positive regulation of cell activation GO:0050867 1 0.013
protein targeting to nucleus GO:0044744 3 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
mitochondrion organization GO:0007005 4 0.013
lymphocyte proliferation GO:0046651 1 0.013
rna 3 end processing GO:0031123 2 0.013
long chain fatty acid metabolic process GO:0001676 1 0.013
regulation of localization GO:0032879 104 0.013
cation transport GO:0006812 81 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
rhodopsin mediated signaling pathway GO:0016056 1 0.013
negative regulation of kinase activity GO:0033673 4 0.013
positive regulation of cell matrix adhesion GO:0001954 1 0.013
gastrulation GO:0007369 208 0.013
regulation of ph GO:0006885 3 0.013
neural tube formation GO:0001841 16 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
gland development GO:0048732 143 0.013
stem cell proliferation GO:0072089 4 0.013
cell death GO:0008219 121 0.012
zymogen activation GO:0031638 3 0.012
entrainment of circadian clock by photoperiod GO:0043153 1 0.012
developmental programmed cell death GO:0010623 4 0.012
positive regulation of cell division GO:0051781 2 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
cellular response to starvation GO:0009267 1 0.012
regulation of cell death GO:0010941 103 0.012
positive regulation of leukocyte mediated immunity GO:0002705 1 0.012
nitric oxide metabolic process GO:0046209 2 0.012
adherens junction assembly GO:0034333 1 0.012
cellular response to organic substance GO:0071310 105 0.012
oxoacid metabolic process GO:0043436 31 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
embryonic organ development GO:0048568 381 0.012
cellular localization GO:0051641 97 0.012
multicellular organismal response to stress GO:0033555 2 0.012
positive regulation of catalytic activity GO:0043085 25 0.012
response to corticosteroid GO:0031960 1 0.012
photoreceptor cell outer segment organization GO:0035845 9 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
positive regulation of epithelial cell migration GO:0010634 2 0.012
heart contraction GO:0060047 71 0.012
death GO:0016265 121 0.011
stem cell division GO:0017145 1 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.011
hydrogen peroxide metabolic process GO:0042743 2 0.011
tube morphogenesis GO:0035239 349 0.011
light induced release of internally sequestered calcium ion GO:0008377 1 0.011
regulation of neurotransmitter secretion GO:0046928 1 0.011
digestive tract development GO:0048565 265 0.011
interaction with host GO:0051701 4 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
regulation of phosphate metabolic process GO:0019220 43 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
cell substrate adhesion GO:0031589 4 0.011
entrainment of circadian clock GO:0009649 2 0.011
detection of external stimulus GO:0009581 24 0.011
rho protein signal transduction GO:0007266 5 0.011
heart morphogenesis GO:0003007 156 0.011
neurotransmitter transport GO:0006836 2 0.011
secondary metabolic process GO:0019748 3 0.011
heart process GO:0003015 71 0.011
defense response GO:0006952 47 0.011
nuclear transport GO:0051169 4 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
positive regulation of gliogenesis GO:0014015 2 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
positive regulation of immune effector process GO:0002699 3 0.011
cellular protein catabolic process GO:0044257 4 0.011
establishment of endothelial barrier GO:0061028 3 0.011
organic cyclic compound metabolic process GO:1901360 301 0.011
cellular protein complex disassembly GO:0043624 1 0.011
regulation of molecular function GO:0065009 70 0.011
rna biosynthetic process GO:0032774 181 0.011
regulation of sodium ion transmembrane transport GO:1902305 1 0.011
cellular ketone metabolic process GO:0042180 11 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
regulation of apoptotic process GO:0042981 98 0.011
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.010
regulation of protein complex disassembly GO:0043244 1 0.010
regulation of ion transmembrane transporter activity GO:0032412 2 0.010
mesodermal cell migration GO:0008078 12 0.010
negative regulation of secretion GO:0051048 2 0.010
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.010
response to nicotine GO:0035094 2 0.010
regulation of anatomical structure size GO:0090066 33 0.010
synaptic vesicle transport GO:0048489 1 0.010
heart development GO:0007507 313 0.010
regulation of sodium ion transport GO:0002028 2 0.010
cell death in response to oxidative stress GO:0036473 2 0.010
single organism biosynthetic process GO:0044711 71 0.010
cellular response to xenobiotic stimulus GO:0071466 35 0.010
inorganic ion transmembrane transport GO:0098660 57 0.010
modification dependent macromolecule catabolic process GO:0043632 3 0.010
response to nutrient GO:0007584 3 0.010
cell substrate junction assembly GO:0007044 2 0.010
regulation of mrna catabolic process GO:0061013 3 0.010
biomineral tissue development GO:0031214 13 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
positive regulation of secretion GO:0051047 1 0.010
protein depolymerization GO:0051261 1 0.010
determination of heart left right asymmetry GO:0061371 117 0.010
negative regulation of cell death GO:0060548 60 0.010
positive regulation of neuron death GO:1901216 1 0.010

crb3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.061
nervous system disease DOID:863 0 0.040
musculoskeletal system disease DOID:17 0 0.014
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
sensory system disease DOID:0050155 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
cardiovascular system disease DOID:1287 0 0.010