Danio rerio

18 known processes

crkl

v-crk sarcoma virus CT10 oncogene homolog (avian)-like

(Aliases: zgc:63469,MGC63469,wu:fj60e01,wu:fa55g05)

crkl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule metabolic process GO:0044260 391 0.519
regulation of cellular metabolic process GO:0031323 320 0.503
Fly
signal transduction GO:0007165 455 0.466
Worm Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.399
regulation of biosynthetic process GO:0009889 250 0.319
protein metabolic process GO:0019538 183 0.257
cellular protein metabolic process GO:0044267 129 0.251
cellular protein modification process GO:0006464 100 0.241
macromolecule modification GO:0043412 111 0.221
modification dependent macromolecule catabolic process GO:0043632 3 0.216
protein localization to nucleus GO:0034504 3 0.196
modification dependent protein catabolic process GO:0019941 3 0.193
positive regulation of biological process GO:0048518 253 0.192
Fly
ubiquitin dependent protein catabolic process GO:0006511 3 0.185
peptidyl serine phosphorylation GO:0018105 1 0.184
regulation of primary metabolic process GO:0080090 311 0.179
protein dephosphorylation GO:0006470 3 0.176
blood vessel development GO:0001568 246 0.174
Mouse
protein modification process GO:0036211 100 0.171
positive regulation of cellular process GO:0048522 201 0.171
Fly
cytoskeleton organization GO:0007010 96 0.166
Worm
apoptotic process GO:0006915 116 0.166
Worm
regulation of response to stimulus GO:0048583 269 0.158
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.157
heterocycle metabolic process GO:0046483 290 0.155
nuclear transport GO:0051169 4 0.147
positive regulation of cell cycle GO:0045787 3 0.145
aging GO:0007568 2 0.144
regulation of developmental process GO:0050793 247 0.139
larval development GO:0002164 2 0.136
single organism organelle organization GO:1902589 199 0.135
Worm
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.134
stem cell proliferation GO:0072089 4 0.132
nucleocytoplasmic transport GO:0006913 4 0.132
generation of neurons GO:0048699 385 0.131
cell surface receptor signaling pathway GO:0007166 325 0.124
stem cell division GO:0017145 1 0.124
microtubule organizing center organization GO:0031023 1 0.123
single organism localization GO:1902578 225 0.122
Worm Fly
nitrogen compound metabolic process GO:0006807 319 0.121
regulation of signal transduction GO:0009966 225 0.115
Fly
cellular protein catabolic process GO:0044257 4 0.115
macromolecular complex subunit organization GO:0043933 74 0.114
single organism nuclear import GO:1902593 3 0.111
protein targeting to nucleus GO:0044744 3 0.111
organelle organization GO:0006996 227 0.107
Worm
proteasomal protein catabolic process GO:0010498 2 0.107
cellular nitrogen compound metabolic process GO:0034641 290 0.106
establishment of protein localization to organelle GO:0072594 4 0.104
mitotic cell cycle process GO:1903047 48 0.102
neuroblast proliferation GO:0007405 2 0.101
stem cell maintenance GO:0019827 4 0.101
regulation of metabolic process GO:0019222 359 0.099
Fly
single organism metabolic process GO:0044710 217 0.098
Fly
muscle structure development GO:0061061 196 0.098
centrosome organization GO:0051297 1 0.097
negative regulation of biological process GO:0048519 304 0.095
regulation of cell differentiation GO:0045595 142 0.095
regulation of circadian rhythm GO:0042752 4 0.095
system process GO:0003008 185 0.094
peptidyl serine modification GO:0018209 2 0.094
maintenance of location GO:0051235 4 0.093
regulation of cellular biosynthetic process GO:0031326 245 0.093
organic cyclic compound metabolic process GO:1901360 301 0.092
organic substance biosynthetic process GO:1901576 289 0.092
rna biosynthetic process GO:0032774 181 0.090
regulation of macromolecule metabolic process GO:0060255 317 0.089
regulation of multicellular organismal process GO:0051239 277 0.087
regulation of nucleic acid templated transcription GO:1903506 213 0.086
regulation of multicellular organismal development GO:2000026 223 0.086
tube morphogenesis GO:0035239 349 0.085
regulation of protein localization to nucleus GO:1900180 2 0.084
positive regulation of cell communication GO:0010647 56 0.082
Fly
cellular component movement GO:0006928 335 0.082
Worm Fly
programmed cell death GO:0012501 119 0.081
Worm
regulation of programmed cell death GO:0043067 101 0.081
regulation of rna metabolic process GO:0051252 224 0.081
cell cycle process GO:0022402 53 0.080
biosynthetic process GO:0009058 294 0.079
nucleobase containing compound biosynthetic process GO:0034654 205 0.079
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.078
Fly
nucleic acid metabolic process GO:0090304 244 0.077
rna metabolic process GO:0016070 219 0.076
blood vessel morphogenesis GO:0048514 216 0.076
embryo development ending in birth or egg hatching GO:0009792 271 0.075
regulation of apoptotic process GO:0042981 98 0.075
macromolecule biosynthetic process GO:0009059 227 0.073
neuron differentiation GO:0030182 353 0.073
nuclear import GO:0051170 3 0.073
establishment of localization GO:0051234 244 0.072
Worm Fly
protein import into nucleus GO:0006606 3 0.071
cellular aromatic compound metabolic process GO:0006725 295 0.070
intracellular signal transduction GO:0035556 85 0.069
Fly
regulation of biological quality GO:0065008 263 0.069
locomotion GO:0040011 313 0.069
Worm Fly
death GO:0016265 121 0.069
Worm
positive regulation of apoptotic signaling pathway GO:2001235 1 0.068
transport GO:0006810 220 0.068
Worm Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.068
regulation of mrna processing GO:0050684 3 0.065
positive regulation of map kinase activity GO:0043406 3 0.064
centrosome cycle GO:0007098 1 0.064
regulation of cell death GO:0010941 103 0.064
gene expression GO:0010467 252 0.063
erk1 and erk2 cascade GO:0070371 4 0.063
positive regulation of transport GO:0051050 2 0.062
response to stress GO:0006950 263 0.062
Fly
cell death GO:0008219 121 0.062
Worm
meiotic cell cycle process GO:1903046 3 0.061
cell motility GO:0048870 244 0.061
Worm Fly
negative regulation of protein kinase activity GO:0006469 4 0.060
cell morphogenesis GO:0000902 289 0.060
locomotor rhythm GO:0045475 3 0.060
vasculature development GO:0001944 278 0.059
Mouse
regulation of protein catabolic process GO:0042176 1 0.059
chordate embryonic development GO:0043009 271 0.058
regulation of nitrogen compound metabolic process GO:0051171 251 0.058
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.058
cellular biosynthetic process GO:0044249 286 0.058
positive regulation of catabolic process GO:0009896 4 0.057
regulation of synapse organization GO:0050807 3 0.057
positive regulation of cellular component biogenesis GO:0044089 3 0.057
enzyme linked receptor protein signaling pathway GO:0007167 106 0.057
cortical actin cytoskeleton organization GO:0030866 1 0.057
cellular component morphogenesis GO:0032989 336 0.057
actin cytoskeleton organization GO:0030036 63 0.057
Worm
regulation of cell communication GO:0010646 232 0.056
Fly
single organism transport GO:0044765 206 0.056
Worm Fly
morphogenesis of an epithelium GO:0002009 333 0.056
regulation of cellular amino acid metabolic process GO:0006521 0 0.056
synaptic growth at neuromuscular junction GO:0051124 2 0.056
anterior posterior pattern specification GO:0009952 152 0.056
Mouse
germ line stem cell maintenance GO:0030718 2 0.055
negative regulation of cellular process GO:0048523 283 0.055
regulation of protein metabolic process GO:0051246 56 0.054
cell substrate adhesion GO:0031589 4 0.054
regulation of transcription dna templated GO:0006355 213 0.052
regulation of cellular amine metabolic process GO:0033238 0 0.051
protein import GO:0017038 3 0.051
regulation of multicellular organism growth GO:0040014 4 0.051
cortical cytoskeleton organization GO:0030865 1 0.051
positive regulation of apoptotic process GO:0043065 29 0.051
multicellular organism growth GO:0035264 4 0.051
angiogenesis GO:0001525 158 0.050
regulation of molecular function GO:0065009 70 0.050
digestive tract development GO:0048565 265 0.050
cognition GO:0050890 1 0.050
extrinsic apoptotic signaling pathway GO:0097191 3 0.050
nucleobase containing compound metabolic process GO:0006139 274 0.049
cellular response to endogenous stimulus GO:0071495 68 0.049
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.049
heart development GO:0007507 313 0.049
Mouse
cell cycle g1 s phase transition GO:0044843 1 0.049
cellular response to external stimulus GO:0071496 2 0.049
regionalization GO:0003002 274 0.049
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.049
amine metabolic process GO:0009308 2 0.048
negative regulation of response to stimulus GO:0048585 104 0.048
regulation of signaling GO:0023051 235 0.048
Fly
regulation of cell development GO:0060284 100 0.047
regulation of establishment of protein localization GO:0070201 4 0.047
actin filament based process GO:0030029 64 0.047
Worm
regulation of stem cell proliferation GO:0072091 2 0.046
nucleic acid templated transcription GO:0097659 181 0.046
organic cyclic compound biosynthetic process GO:1901362 223 0.045
cellular response to extracellular stimulus GO:0031668 2 0.045
segmentation GO:0035282 97 0.045
mitochondrion organization GO:0007005 4 0.045
negative regulation of macromolecule metabolic process GO:0010605 76 0.045
regulation of mrna splicing via spliceosome GO:0048024 3 0.044
positive regulation of cellular catabolic process GO:0031331 3 0.044
apoptotic process involved in development GO:1902742 2 0.044
regulation of purine nucleotide catabolic process GO:0033121 2 0.044
negative regulation of kinase activity GO:0033673 4 0.044
guanosine containing compound metabolic process GO:1901068 4 0.043
positive regulation of macromolecule metabolic process GO:0010604 93 0.043
mitotic dna integrity checkpoint GO:0044774 4 0.043
cellular carbohydrate metabolic process GO:0044262 4 0.043
aromatic compound biosynthetic process GO:0019438 217 0.042
cellular macromolecule biosynthetic process GO:0034645 224 0.042
regulation of gene expression GO:0010468 265 0.042
negative regulation of protein phosphorylation GO:0001933 4 0.042
g1 s transition of mitotic cell cycle GO:0000082 1 0.042
regulation of gtp catabolic process GO:0033124 2 0.041
regulation of nucleotide catabolic process GO:0030811 2 0.041
positive regulation of stress activated mapk cascade GO:0032874 3 0.041
Fly
cytoskeleton dependent cytokinesis GO:0061640 3 0.041
regulation of nucleoside metabolic process GO:0009118 2 0.040
regulation of receptor activity GO:0010469 2 0.040
mitotic cell cycle GO:0000278 64 0.040
positive regulation of response to stimulus GO:0048584 80 0.040
Fly
regulation of intracellular protein transport GO:0033157 3 0.040
cellular amine metabolic process GO:0044106 2 0.040
cellular response to stress GO:0033554 62 0.040
Fly
phosphorus metabolic process GO:0006793 109 0.040
Fly
positive regulation of programmed cell death GO:0043068 29 0.040
gtp catabolic process GO:0006184 2 0.040
cellular catabolic process GO:0044248 27 0.039
cytoplasm organization GO:0007028 4 0.039
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.039
cellular localization GO:0051641 97 0.039
heterocycle biosynthetic process GO:0018130 215 0.039
regulation of erk1 and erk2 cascade GO:0070372 4 0.038
entrainment of circadian clock GO:0009649 2 0.038
regulation of nervous system development GO:0051960 90 0.038
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.038
rna localization GO:0006403 4 0.038
pole plasm assembly GO:0007315 4 0.038
organic substance catabolic process GO:1901575 28 0.038
regulation of reproductive process GO:2000241 4 0.038
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.037
regulation of protein targeting GO:1903533 2 0.037
cellular component biogenesis GO:0044085 178 0.037
guanosine containing compound catabolic process GO:1901069 2 0.037
regulation of protein transport GO:0051223 3 0.037
response to chemical GO:0042221 320 0.037
cell projection organization GO:0030030 284 0.037
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.037
macromolecule catabolic process GO:0009057 15 0.037
regulation of synapse assembly GO:0051963 3 0.037
regulation of anatomical structure morphogenesis GO:0022603 130 0.037
regulation of gtpase activity GO:0043087 2 0.036
regulation of cellular ketone metabolic process GO:0010565 7 0.036
regulation of organelle organization GO:0033043 29 0.036
regulation of neurogenesis GO:0050767 87 0.035
localization of cell GO:0051674 244 0.035
Worm Fly
centrosome duplication GO:0051298 1 0.035
cell division GO:0051301 20 0.035
cytokinesis GO:0000910 3 0.035
mitotic nuclear division GO:0007067 18 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.034
neuron development GO:0048666 262 0.034
meiotic nuclear division GO:0007126 4 0.034
negative regulation of metabolic process GO:0009892 86 0.034
regulation of stem cell differentiation GO:2000736 4 0.034
cellular amino acid metabolic process GO:0006520 7 0.033
regulation of protein ubiquitination GO:0031396 3 0.033
autophagy GO:0006914 4 0.033
gtp metabolic process GO:0046039 4 0.033
regulation of intracellular signal transduction GO:1902531 57 0.033
Fly
mitotic dna damage checkpoint GO:0044773 4 0.032
small gtpase mediated signal transduction GO:0007264 8 0.032
axis specification GO:0009798 43 0.032
chemotaxis GO:0006935 104 0.032
regulation of rna biosynthetic process GO:2001141 213 0.032
response to organic substance GO:0010033 153 0.032
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.031
meiotic chromosome segregation GO:0045132 3 0.031
neuron projection morphogenesis GO:0048812 161 0.031
response to abiotic stimulus GO:0009628 122 0.031
regulation of mitotic cell cycle GO:0007346 25 0.031
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.031
signal transduction in absence of ligand GO:0038034 1 0.031
regulation of cellular protein catabolic process GO:1903362 1 0.031
regulation of localization GO:0032879 104 0.030
central nervous system development GO:0007417 387 0.030
dorsal ventral pattern formation GO:0009953 125 0.030
positive regulation of protein complex assembly GO:0031334 2 0.030
gastrulation GO:0007369 208 0.030
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.029
nuclear division GO:0000280 23 0.029
negative regulation of catabolic process GO:0009895 3 0.029
regulation of neural precursor cell proliferation GO:2000177 3 0.029
response to radiation GO:0009314 51 0.029
cell part morphogenesis GO:0032990 246 0.028
response to external stimulus GO:0009605 264 0.028
mrna metabolic process GO:0016071 20 0.028
muscle organ development GO:0007517 101 0.028
ras protein signal transduction GO:0007265 7 0.028
regulation of proteolysis GO:0030162 24 0.028
cellular macromolecule catabolic process GO:0044265 12 0.028
negative regulation of developmental process GO:0051093 65 0.028
embryonic pattern specification GO:0009880 44 0.027
phosphate containing compound metabolic process GO:0006796 108 0.027
Fly
head development GO:0060322 303 0.027
lipid storage GO:0019915 1 0.027
cellular component disassembly GO:0022411 1 0.027
developmental programmed cell death GO:0010623 4 0.027
reproduction GO:0000003 40 0.027
Fly
protein polyubiquitination GO:0000209 4 0.026
adult behavior GO:0030534 2 0.026
convergent extension GO:0060026 118 0.026
adherens junction organization GO:0034332 4 0.026
regulation of phosphorylation GO:0042325 26 0.026
Fly
negative regulation of cell differentiation GO:0045596 46 0.026
cell migration involved in gastrulation GO:0042074 79 0.026
positive regulation of jnk cascade GO:0046330 3 0.026
Fly
positive regulation of signaling GO:0023056 56 0.026
Fly
cellular component assembly GO:0022607 170 0.026
small molecule metabolic process GO:0044281 77 0.026
epithelial tube morphogenesis GO:0060562 148 0.026
regulation of chromosome segregation GO:0051983 1 0.026
response to endogenous stimulus GO:0009719 83 0.025
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.025
regulation of microtubule cytoskeleton organization GO:0070507 3 0.025
regulation of cellular component organization GO:0051128 86 0.025
exocytosis GO:0006887 1 0.025
positive regulation of cellular amine metabolic process GO:0033240 0 0.025
cellular ketone metabolic process GO:0042180 11 0.025
phosphorylation GO:0016310 69 0.025
Fly
response to alkaloid GO:0043279 2 0.025
protein complex subunit organization GO:0071822 46 0.025
forebrain cell migration GO:0021885 1 0.024
developmental growth GO:0048589 166 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.024
lamellipodium assembly GO:0030032 1 0.024
syncytium formation GO:0006949 12 0.024
spermatid differentiation GO:0048515 2 0.024
activation of mapk activity GO:0000187 3 0.024
oxoacid metabolic process GO:0043436 31 0.024
renal tubule morphogenesis GO:0061333 1 0.024
immune system process GO:0002376 241 0.024
Mouse
positive regulation of ras protein signal transduction GO:0046579 1 0.024
cellular response to radiation GO:0071478 4 0.024
taxis GO:0042330 109 0.024
alternative mrna splicing via spliceosome GO:0000380 1 0.024
digestive system development GO:0055123 289 0.023
negative regulation of nuclear division GO:0051784 3 0.023
cell projection morphogenesis GO:0048858 244 0.023
cell cycle phase transition GO:0044770 9 0.023
homeostatic process GO:0042592 142 0.023
negative regulation of multicellular organismal process GO:0051241 69 0.023
regulation of cell cycle GO:0051726 52 0.023
striated muscle cell differentiation GO:0051146 129 0.023
positive regulation of nucleoside metabolic process GO:0045979 1 0.023
single organism biosynthetic process GO:0044711 71 0.023
mitotic cell cycle phase transition GO:0044772 9 0.023
sensory perception of pain GO:0019233 1 0.022
wnt signaling pathway GO:0016055 80 0.022
regulation of protein binding GO:0043393 3 0.022
stem cell differentiation GO:0048863 117 0.022
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.022
transcription dna templated GO:0006351 181 0.022
cell morphogenesis involved in differentiation GO:0000904 195 0.022
organic acid metabolic process GO:0006082 31 0.022
multicellular organismal reproductive process GO:0048609 35 0.022
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.022
cell fate commitment GO:0045165 99 0.022
transcription from rna polymerase ii promoter GO:0006366 80 0.022
positive regulation of transcription dna templated GO:0045893 57 0.022
regulation of binding GO:0051098 3 0.022
embryonic organ morphogenesis GO:0048562 274 0.022
cell matrix adhesion GO:0007160 4 0.022
regulation of protein import into nucleus GO:0042306 2 0.022
regulation of nucleocytoplasmic transport GO:0046822 2 0.021
nephron tubule morphogenesis GO:0072078 1 0.021
axon development GO:0061564 166 0.021
axonogenesis GO:0007409 152 0.021
myotube differentiation GO:0014902 45 0.021
positive regulation of cell adhesion GO:0045785 1 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.021
positive regulation of cell division GO:0051781 2 0.021
neurological system process GO:0050877 62 0.021
gland development GO:0048732 143 0.021
Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.021
nephron epithelium morphogenesis GO:0072088 1 0.020
cell migration GO:0016477 237 0.020
Worm Fly
cell proliferation GO:0008283 80 0.020
epithelial cell morphogenesis GO:0003382 2 0.020
protein phosphorylation GO:0006468 47 0.020
glial cell proliferation GO:0014009 4 0.020
energy reserve metabolic process GO:0006112 2 0.020
hepaticobiliary system development GO:0061008 98 0.020
somite development GO:0061053 96 0.020
oocyte anterior posterior axis specification GO:0007314 4 0.020
regulation of jak stat cascade GO:0046425 3 0.020
embryonic skeletal system development GO:0048706 97 0.020
regulation of cellular protein metabolic process GO:0032268 52 0.020
regulation of receptor mediated endocytosis GO:0048259 4 0.020
cellular response to nutrient levels GO:0031669 2 0.020
regulation of cell shape GO:0008360 1 0.019
negative regulation of mapk cascade GO:0043409 4 0.019
single organism reproductive process GO:0044702 40 0.019
Fly
cellular response to chemical stimulus GO:0070887 157 0.019
neuron projection development GO:0031175 180 0.019
catabolic process GO:0009056 32 0.019
positive regulation of signal transduction GO:0009967 56 0.019
Fly
positive regulation of gtpase activity GO:0043547 1 0.019
cytokinetic process GO:0032506 2 0.019
eye development GO:0001654 277 0.019
somitogenesis GO:0001756 87 0.019
positive regulation of secretion GO:0051047 1 0.019
microtubule based process GO:0007017 60 0.019
hemopoiesis GO:0030097 183 0.019
brain development GO:0007420 293 0.018
negative regulation of cellular metabolic process GO:0031324 77 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.018
regulation of axonogenesis GO:0050770 32 0.018
secondary metabolic process GO:0019748 3 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
cell cycle GO:0007049 93 0.018
myoblast fusion GO:0007520 10 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
lateral inhibition GO:0046331 1 0.018
muscle cell differentiation GO:0042692 139 0.018
regulation of dendrite development GO:0050773 3 0.018
skeletal system morphogenesis GO:0048705 102 0.018
g2 dna damage checkpoint GO:0031572 3 0.018
negative regulation of protein localization to nucleus GO:1900181 2 0.018
negative regulation of ras protein signal transduction GO:0046580 1 0.018
negative regulation of cellular catabolic process GO:0031330 3 0.018
developmental growth involved in morphogenesis GO:0060560 86 0.018
actin polymerization or depolymerization GO:0008154 2 0.018
compound eye development GO:0048749 2 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.018
protein localization to plasma membrane GO:0072659 1 0.018
skeletal system development GO:0001501 181 0.018
membrane invagination GO:0010324 1 0.018
Worm Fly
regulation of cytoplasmic transport GO:1903649 4 0.018
protein homooligomerization GO:0051260 3 0.017
regulation of transport GO:0051049 45 0.017
synaptic vesicle transport GO:0048489 1 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.017
intracellular mrna localization GO:0008298 1 0.017
negative regulation of biosynthetic process GO:0009890 55 0.017
negative regulation of protein transport GO:0051224 3 0.017
neural precursor cell proliferation GO:0061351 20 0.017
locomotory behavior GO:0007626 34 0.017
peptidyl threonine phosphorylation GO:0018107 1 0.017
negative regulation of cell communication GO:0010648 96 0.017
cellular response to starvation GO:0009267 1 0.017
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.017
organelle fission GO:0048285 23 0.017
liver development GO:0001889 96 0.017
peptidyl amino acid modification GO:0018193 16 0.017
macroautophagy GO:0016236 1 0.017
negative regulation of cell cycle phase transition GO:1901988 5 0.017
negative regulation of intracellular protein transport GO:0090317 3 0.017
mitotic cytokinesis GO:0000281 3 0.017
regulation of catalytic activity GO:0050790 55 0.017
cell junction maintenance GO:0034331 2 0.017
circadian regulation of gene expression GO:0032922 8 0.017
specification of symmetry GO:0009799 204 0.016
multi organism process GO:0051704 134 0.016
Fly
circadian rhythm GO:0007623 19 0.016
ameboidal type cell migration GO:0001667 143 0.016
Fly
meiosis i GO:0007127 1 0.016
nuclear export GO:0051168 1 0.016
embryonic organ development GO:0048568 381 0.016
convergent extension involved in gastrulation GO:0060027 71 0.016
maternal determination of anterior posterior axis embryo GO:0008358 4 0.016
er to golgi vesicle mediated transport GO:0006888 1 0.016
positive regulation of neuron apoptotic process GO:0043525 1 0.016
regulation of phosphorus metabolic process GO:0051174 43 0.016
Fly
regulation of cytokine production GO:0001817 3 0.016
peptide transport GO:0015833 1 0.016
positive regulation of cell death GO:0010942 29 0.016
inner ear development GO:0048839 126 0.016
negative regulation of reproductive process GO:2000242 3 0.016
eye morphogenesis GO:0048592 144 0.016
regulation of filopodium assembly GO:0051489 2 0.015
nephron morphogenesis GO:0072028 2 0.015
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.015
negative regulation of synapse assembly GO:0051964 2 0.015
regulation of dendrite morphogenesis GO:0048814 3 0.015
single organism cellular localization GO:1902580 46 0.015
regulation of metal ion transport GO:0010959 4 0.015
somatic muscle development GO:0007525 4 0.015
positive regulation of metabolic process GO:0009893 108 0.015
Fly
organelle assembly GO:0070925 110 0.015
regulation of cellular response to growth factor stimulus GO:0090287 35 0.015
negative regulation of intracellular transport GO:0032387 3 0.015
regulation of synaptic plasticity GO:0048167 1 0.015
negative regulation of cell cycle GO:0045786 14 0.015
cellular response to hormone stimulus GO:0032870 39 0.015
positive regulation of stem cell proliferation GO:2000648 1 0.015
sensory organ morphogenesis GO:0090596 200 0.015
organelle localization GO:0051640 49 0.015
single organism membrane fusion GO:0044801 2 0.015
regulation of vasculature development GO:1901342 33 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.014
behavior GO:0007610 74 0.014
protein heterooligomerization GO:0051291 1 0.014
multicellular organism reproduction GO:0032504 35 0.014
Fly
translational initiation GO:0006413 3 0.014
phagocytosis GO:0006909 3 0.014
Worm Fly
gamete generation GO:0007276 33 0.014
Fly
embryonic skeletal system morphogenesis GO:0048704 93 0.014
golgi vesicle transport GO:0048193 3 0.014
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.014
regulation of wnt signaling pathway GO:0030111 53 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
positive regulation of rna metabolic process GO:0051254 59 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
cellular response to oxygen levels GO:0071453 1 0.014
mitotic g2 dna damage checkpoint GO:0007095 3 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.014
regulation of phosphate metabolic process GO:0019220 43 0.014
Fly
negative regulation of signal transduction GO:0009968 94 0.014
positive regulation of cell substrate adhesion GO:0010811 1 0.014
response to unfolded protein GO:0006986 2 0.014
response to nitrogen compound GO:1901698 19 0.014
sensory organ development GO:0007423 393 0.014
growth GO:0040007 174 0.014
positive regulation of muscle cell differentiation GO:0051149 1 0.014
rho protein signal transduction GO:0007266 5 0.014

crkl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.046
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.021