Danio rerio

12 known processes

cryaa

crystallin, alpha A

(Aliases: wu:fc06h04,zgc:92036,MGC92036,fc06h04)

cryaa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to abiotic stimulus GO:0009628 122 0.563
Zebrafish Mouse
response to chemical GO:0042221 320 0.331
Zebrafish Mouse
sensory organ development GO:0007423 393 0.316
system process GO:0003008 185 0.282
Zebrafish
response to stress GO:0006950 263 0.187
Zebrafish Mouse
sensory perception GO:0007600 39 0.176
immune system process GO:0002376 241 0.176
lens development in camera type eye GO:0002088 22 0.163
Mouse
single organism localization GO:1902578 225 0.136
eye development GO:0001654 277 0.134
ion transmembrane transport GO:0034220 91 0.124
membrane repolarization GO:0086009 2 0.099
sequestering of calcium ion GO:0051208 3 0.099
response to organic substance GO:0010033 153 0.096
ion transport GO:0006811 114 0.094
response to inorganic substance GO:0010035 38 0.094
Mouse
cellular response to chemical stimulus GO:0070887 157 0.086
response to endogenous stimulus GO:0009719 83 0.086
single organism transport GO:0044765 206 0.076
cellular response to external stimulus GO:0071496 2 0.075
transmembrane transport GO:0055085 120 0.072
gall bladder development GO:0061010 1 0.071
lipid catabolic process GO:0016042 4 0.068
positive regulation of catabolic process GO:0009896 4 0.068
stem cell proliferation GO:0072089 4 0.067
sensory perception of mechanical stimulus GO:0050954 16 0.066
tissue regeneration GO:0042246 74 0.064
multicellular organism growth GO:0035264 4 0.063
regulation of sequestering of calcium ion GO:0051282 4 0.062
establishment of localization GO:0051234 244 0.056
single organism metabolic process GO:0044710 217 0.054
regulation of anterior head development GO:2000742 2 0.053
cellular aromatic compound metabolic process GO:0006725 295 0.052
positive regulation of cellular catabolic process GO:0031331 3 0.052
positive regulation of biological process GO:0048518 253 0.052
Mouse
response to radiation GO:0009314 51 0.051
Mouse
cell death GO:0008219 121 0.050
Mouse
striated muscle cell development GO:0055002 108 0.050
regulation of multicellular organism growth GO:0040014 4 0.049
aging GO:0007568 2 0.048
Worm
regulation of cellular metabolic process GO:0031323 320 0.048
Mouse
response to metal ion GO:0010038 34 0.046
response to organic cyclic compound GO:0014070 51 0.045
negative regulation of feeding behavior GO:2000252 2 0.044
positive regulation of cellular process GO:0048522 201 0.043
Mouse
camera type eye development GO:0043010 222 0.042
Mouse
divalent inorganic cation homeostasis GO:0072507 22 0.042
gene expression GO:0010467 252 0.042
Mouse
response to lipid GO:0033993 60 0.042
cell motility GO:0048870 244 0.039
transport GO:0006810 220 0.039
muscle fiber development GO:0048747 52 0.039
post embryonic foregut morphogenesis GO:0048618 3 0.037
organic cyclic compound metabolic process GO:1901360 301 0.037
chemical homeostasis GO:0048878 49 0.036
regulation of multicellular organismal process GO:0051239 277 0.036
Zebrafish
regulation of protein catabolic process GO:0042176 1 0.036
single organism biosynthetic process GO:0044711 71 0.035
cellular catabolic process GO:0044248 27 0.035
hepatic duct development GO:0061011 2 0.034
anterior head development GO:0097065 2 0.034
positive regulation of molecular function GO:0044093 33 0.033
mitochondrion organization GO:0007005 4 0.033
Mouse
organic substance biosynthetic process GO:1901576 289 0.033
sequestering of metal ion GO:0051238 3 0.032
locomotion GO:0040011 313 0.031
maintenance of location GO:0051235 4 0.031
positive regulation of cell communication GO:0010647 56 0.030
response to alkaloid GO:0043279 2 0.030
cation homeostasis GO:0055080 33 0.030
lipid biosynthetic process GO:0008610 22 0.030
glucose homeostasis GO:0042593 1 0.029
death GO:0016265 121 0.028
Mouse
endochondral bone growth GO:0003416 2 0.028
positive regulation of metabolic process GO:0009893 108 0.028
Mouse
signal transduction GO:0007165 455 0.027
response to arsenic containing substance GO:0046685 5 0.027
Zebrafish
cation transmembrane transport GO:0098655 65 0.027
developmental maturation GO:0021700 34 0.027
anion transmembrane transport GO:0098656 12 0.027
cellular component movement GO:0006928 335 0.027
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.027
rna metabolic process GO:0016070 219 0.027
regulation of apoptotic process GO:0042981 98 0.027
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.026
Mouse
cellular protein catabolic process GO:0044257 4 0.026
response to oxygen containing compound GO:1901700 55 0.026
Mouse
positive regulation of cellular component biogenesis GO:0044089 3 0.026
regulation of proteolysis GO:0030162 24 0.026
Mouse
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.025
regulation of mesenchymal cell proliferation GO:0010464 1 0.025
oxidation reduction process GO:0055114 41 0.025
programmed cell death GO:0012501 119 0.025
Mouse
myotube cell development GO:0014904 35 0.025
cation transport GO:0006812 81 0.025
organic cyclic compound biosynthetic process GO:1901362 223 0.024
response to hormone GO:0009725 48 0.024
angiogenesis GO:0001525 158 0.024
regulation of response to stimulus GO:0048583 269 0.024
regulation of lipid catabolic process GO:0050994 2 0.024
regulation of muscle hypertrophy GO:0014743 2 0.024
Zebrafish
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.024
axon regeneration GO:0031103 14 0.024
cellular response to hormone stimulus GO:0032870 39 0.024
astrocyte differentiation GO:0048708 1 0.023
regulation of biological quality GO:0065008 263 0.023
Zebrafish
fin regeneration GO:0031101 51 0.023
negative regulation of sequestering of calcium ion GO:0051283 4 0.023
inorganic anion transport GO:0015698 25 0.023
regulation of membrane potential GO:0042391 23 0.022
response to xenobiotic stimulus GO:0009410 45 0.022
regulation of protein transport GO:0051223 3 0.022
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.022
embryonic organ development GO:0048568 381 0.022
Mouse
insulin like growth factor receptor signaling pathway GO:0048009 4 0.022
sensory perception of light stimulus GO:0050953 19 0.022
neurological system process GO:0050877 62 0.021
response to salt stress GO:0009651 10 0.021
stem cell division GO:0017145 1 0.021
proteolysis GO:0006508 38 0.021
Mouse
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.021
regulation of multicellular organismal development GO:2000026 223 0.021
monoamine transport GO:0015844 1 0.021
regulation of metabolic process GO:0019222 359 0.021
Mouse
sensory organ morphogenesis GO:0090596 200 0.020
Mouse
nitrogen compound metabolic process GO:0006807 319 0.020
cellular response to organic substance GO:0071310 105 0.020
adult behavior GO:0030534 2 0.020
cellular response to organic cyclic compound GO:0071407 38 0.020
homeostatic process GO:0042592 142 0.020
cellular ketone metabolic process GO:0042180 11 0.019
endocardium morphogenesis GO:0003160 4 0.019
negative regulation of dna metabolic process GO:0051053 4 0.019
localization of cell GO:0051674 244 0.019
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.019
regulation of cell communication GO:0010646 232 0.019
activation of mapk activity GO:0000187 3 0.018
response to nicotine GO:0035094 2 0.018
positive regulation of transport GO:0051050 2 0.018
protein localization to membrane GO:0072657 9 0.018
regulation of circadian rhythm GO:0042752 4 0.018
action potential GO:0001508 19 0.018
regulation of bone mineralization GO:0030500 2 0.018
negative regulation of apoptotic process GO:0043066 55 0.018
Mouse
skeletal muscle fiber development GO:0048741 35 0.018
regulation of developmental process GO:0050793 247 0.018
regulation of signaling GO:0023051 235 0.017
cellular response to lipid GO:0071396 39 0.017
secondary metabolic process GO:0019748 3 0.016
endocardium formation GO:0060214 1 0.016
regulation of signal transduction GO:0009966 225 0.016
developmental programmed cell death GO:0010623 4 0.016
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.016
pigmentation GO:0043473 85 0.016
chondrocyte intercalation involved in growth plate cartilage morphogenesis GO:0003428 1 0.016
regulation of nervous system development GO:0051960 90 0.016
developmental growth GO:0048589 166 0.016
behavior GO:0007610 74 0.016
regulation of cell death GO:0010941 103 0.016
Mouse
carbohydrate derivative metabolic process GO:1901135 61 0.016
growth plate cartilage development GO:0003417 2 0.016
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.016
organic acid metabolic process GO:0006082 31 0.015
regulation of biosynthetic process GO:0009889 250 0.015
small molecule metabolic process GO:0044281 77 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
regulation of cell development GO:0060284 100 0.015
muscle hypertrophy GO:0014896 2 0.015
Zebrafish
heterocycle metabolic process GO:0046483 290 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
cellular nitrogen compound metabolic process GO:0034641 290 0.015
cell surface receptor signaling pathway GO:0007166 325 0.015
positive regulation of cell division GO:0051781 2 0.015
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.015
negative regulation of programmed cell death GO:0043069 58 0.015
Mouse
mesenchymal cell proliferation GO:0010463 1 0.014
response to glucose GO:0009749 3 0.014
ion homeostasis GO:0050801 41 0.014
wound healing GO:0042060 90 0.014
response to transition metal nanoparticle GO:1990267 28 0.014
phototransduction GO:0007602 2 0.014
regeneration GO:0031099 91 0.014
metal ion homeostasis GO:0055065 26 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
positive regulation of multicellular organismal process GO:0051240 52 0.014
cellular macromolecule metabolic process GO:0044260 391 0.014
Mouse
nucleic acid metabolic process GO:0090304 244 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
apoptotic process GO:0006915 116 0.013
Mouse
positive regulation of stem cell proliferation GO:2000648 1 0.013
hepatocyte proliferation GO:0072574 2 0.013
response to wounding GO:0009611 116 0.013
regulation of programmed cell death GO:0043067 101 0.013
Mouse
circulatory system process GO:0003013 87 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
growth plate cartilage morphogenesis GO:0003422 1 0.013
response to external stimulus GO:0009605 264 0.013
compound eye development GO:0048749 2 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
regulation of neurogenesis GO:0050767 87 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
regulation of developmental growth GO:0048638 38 0.013
larval development GO:0002164 2 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
steroid biosynthetic process GO:0006694 5 0.012
blood circulation GO:0008015 87 0.012
positive regulation of neural precursor cell proliferation GO:2000179 1 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
catechol containing compound biosynthetic process GO:0009713 2 0.012
positive regulation of lipid metabolic process GO:0045834 1 0.012
blood vessel morphogenesis GO:0048514 216 0.012
embryonic hemopoiesis GO:0035162 53 0.012
protein targeting to nucleus GO:0044744 3 0.012
positive regulation of wound healing GO:0090303 1 0.012
regulation of systemic arterial blood pressure GO:0003073 1 0.012
regulation of homeostatic process GO:0032844 9 0.011
organonitrogen compound metabolic process GO:1901564 74 0.011
nephron epithelium morphogenesis GO:0072088 1 0.011
embryonic skeletal joint morphogenesis GO:0060272 3 0.011
tissue remodeling GO:0048771 4 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
light induced release of internally sequestered calcium ion GO:0008377 1 0.011
negative regulation of blood circulation GO:1903523 2 0.011
regulation of intracellular ph GO:0051453 1 0.011
optic placode formation GO:0001743 4 0.011
response to food GO:0032094 1 0.011
amino acid transport GO:0006865 2 0.011
septum transversum development GO:0003343 4 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
auditory receptor cell fate determination GO:0042668 2 0.011
cell part morphogenesis GO:0032990 246 0.011
regulation of cellular ph GO:0030641 1 0.011
foregut morphogenesis GO:0007440 4 0.011
regulation of tube size GO:0035150 2 0.010
oxoacid metabolic process GO:0043436 31 0.010
regulation of cytoplasmic transport GO:1903649 4 0.010
cellular nitrogen compound biosynthetic process GO:0044271 218 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
regulation of blood pressure GO:0008217 1 0.010
small molecule biosynthetic process GO:0044283 16 0.010
cellular response to nutrient levels GO:0031669 2 0.010
regulation of cell activation GO:0050865 1 0.010
calcium ion homeostasis GO:0055074 19 0.010
inner ear receptor cell fate commitment GO:0060120 4 0.010
response to oxygen levels GO:0070482 25 0.010
Mouse
rna biosynthetic process GO:0032774 181 0.010
actomyosin structure organization GO:0031032 53 0.010

cryaa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.074
immune system disease DOID:2914 0 0.040
musculoskeletal system disease DOID:17 0 0.029
hematopoietic system disease DOID:74 0 0.012
connective tissue disease DOID:65 0 0.010
bone development disease DOID:0080006 0 0.010
bone disease DOID:0080001 0 0.010