|
|
gene expression
|
GO:0010467 |
252 |
0.702
|
Yeast Mouse |
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.687
|
Yeast |
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.686
|
Human Mouse Fly |
|
|
apoptotic process
|
GO:0006915 |
116 |
0.647
|
Fly |
|
|
regulation of cellular macromolecule biosynthetic process
|
GO:2000112 |
222 |
0.614
|
|
|
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.604
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.602
|
|
|
|
programmed cell death
|
GO:0012501 |
119 |
0.573
|
Fly |
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
213 |
0.545
|
|
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.526
|
|
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.523
|
|
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.519
|
Mouse |
|
|
regulation of developmental process
|
GO:0050793 |
247 |
0.508
|
Worm |
|
|
cell death
|
GO:0008219 |
121 |
0.498
|
Fly |
|
|
meiotic nuclear division
|
GO:0007126 |
4 |
0.482
|
Yeast |
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.478
|
Yeast |
|
|
signal transduction
|
GO:0007165 |
455 |
0.465
|
Human Fly |
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.450
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
56 |
0.448
|
Human |
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.446
|
|
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.440
|
|
|
|
death
|
GO:0016265 |
121 |
0.427
|
Fly |
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.424
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.423
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.421
|
Worm |
|
|
vasculature development
|
GO:0001944 |
278 |
0.410
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.404
|
|
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.404
|
Human Yeast Zebrafish Mouse Rat Fly |
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.390
|
Human |
|
|
meiotic chromosome segregation
|
GO:0045132 |
3 |
0.386
|
Yeast |
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.386
|
Yeast |
|
|
negative regulation of mitosis
|
GO:0045839 |
3 |
0.385
|
|
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.384
|
Yeast |
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.381
|
|
|
|
cell cycle process
|
GO:0022402 |
53 |
0.375
|
Human Yeast |
|
|
larval development
|
GO:0002164 |
2 |
0.366
|
Worm |
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.353
|
Human Mouse Fly |
|
|
ameboidal type cell migration
|
GO:0001667 |
143 |
0.349
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
85 |
0.347
|
|
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.339
|
|
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.337
|
Yeast |
|
|
blood vessel morphogenesis
|
GO:0048514 |
216 |
0.337
|
|
|
|
blood vessel development
|
GO:0001568 |
246 |
0.336
|
|
|
|
cellular response to stress
|
GO:0033554 |
62 |
0.333
|
Yeast |
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.319
|
|
|
|
muscle structure development
|
GO:0061061 |
196 |
0.312
|
|
|
|
organelle fission
|
GO:0048285 |
23 |
0.310
|
Yeast |
|
|
localization of cell
|
GO:0051674 |
244 |
0.305
|
|
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.300
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
96 |
0.294
|
|
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.286
|
|
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.273
|
Human Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
48 |
0.273
|
Yeast |
|
|
regulation of cell death
|
GO:0010941 |
103 |
0.272
|
Fly |
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.270
|
Human |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
29 |
0.266
|
|
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.264
|
|
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.258
|
Human Fly |
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.257
|
|
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.257
|
|
|
|
single organism transport
|
GO:0044765 |
206 |
0.251
|
Yeast Fly |
|
|
negative regulation of signal transduction
|
GO:0009968 |
94 |
0.245
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
231 |
0.243
|
|
|
|
digestive system development
|
GO:0055123 |
289 |
0.243
|
|
|
|
digestive tract development
|
GO:0048565 |
265 |
0.242
|
|
|
|
aging
|
GO:0007568 |
2 |
0.242
|
|
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.237
|
Yeast |
|
|
heart development
|
GO:0007507 |
313 |
0.237
|
Zebrafish |
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.234
|
|
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.230
|
Human Mouse Fly |
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.230
|
Yeast Fly |
|
|
maintenance of location
|
GO:0051235 |
4 |
0.229
|
Yeast |
|
|
rna modification
|
GO:0009451 |
2 |
0.226
|
Yeast |
|
|
response to stress
|
GO:0006950 |
263 |
0.226
|
Yeast |
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.222
|
|
|
|
neuron development
|
GO:0048666 |
262 |
0.219
|
|
|
|
regionalization
|
GO:0003002 |
274 |
0.218
|
|
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.216
|
Fly |
|
|
negative regulation of cell cycle
|
GO:0045786 |
14 |
0.213
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
101 |
0.208
|
Fly |
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.208
|
Yeast |
|
|
positive regulation of cell communication
|
GO:0010647 |
56 |
0.206
|
Human |
|
|
central nervous system development
|
GO:0007417 |
387 |
0.206
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.206
|
Fly |
|
|
stem cell maintenance
|
GO:0019827 |
4 |
0.205
|
|
|
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.200
|
|
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.196
|
|
|
|
cell migration
|
GO:0016477 |
237 |
0.193
|
|
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.192
|
Yeast |
|
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.191
|
|
|
|
angiogenesis
|
GO:0001525 |
158 |
0.191
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
69 |
0.187
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
29 |
0.186
|
|
|
|
locomotion
|
GO:0040011 |
313 |
0.184
|
Worm |
|
|
single organism organelle organization
|
GO:1902589 |
199 |
0.183
|
Human Yeast |
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.183
|
Human Mouse Fly |
|
|
response to chemical
|
GO:0042221 |
320 |
0.181
|
Fly |
|
|
peptidyl serine modification
|
GO:0018209 |
2 |
0.180
|
Zebrafish |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
29 |
0.180
|
|
|
|
eye development
|
GO:0001654 |
277 |
0.174
|
Fly |
|
|
single organism localization
|
GO:1902578 |
225 |
0.174
|
Yeast Fly |
|
|
phosphorus metabolic process
|
GO:0006793 |
109 |
0.170
|
Human Yeast Zebrafish Mouse Rat Fly |
|
|
meiotic cell cycle process
|
GO:1903046 |
3 |
0.167
|
Yeast |
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.167
|
|
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.165
|
Fly |
|
|
head development
|
GO:0060322 |
303 |
0.164
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
1 |
0.162
|
Zebrafish |
|
|
generation of neurons
|
GO:0048699 |
385 |
0.161
|
Fly |
|
|
gastrulation
|
GO:0007369 |
208 |
0.159
|
|
|
|
negative regulation of nuclear division
|
GO:0051784 |
3 |
0.159
|
|
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.157
|
|
|
|
cell motility
|
GO:0048870 |
244 |
0.157
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
56 |
0.154
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
57 |
0.153
|
|
|
|
cell growth
|
GO:0016049 |
57 |
0.153
|
Fly |
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.151
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
9 |
0.146
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
80 |
0.145
|
Human Fly |
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
4 |
0.145
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
3 |
0.143
|
Mouse Fly |
|
|
dorsal ventral pattern formation
|
GO:0009953 |
125 |
0.140
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
56 |
0.139
|
Human Mouse Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.138
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
80 |
0.138
|
Human |
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.137
|
Human Yeast Zebrafish Mouse Rat Fly |
|
|
stem cell division
|
GO:0017145 |
1 |
0.137
|
|
|
|
organelle organization
|
GO:0006996 |
227 |
0.135
|
Human Yeast |
|
|
negative regulation of response to stimulus
|
GO:0048585 |
104 |
0.135
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.134
|
Fly |
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
93 |
0.134
|
Human Mouse Fly |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
58 |
0.133
|
Fly |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
3 |
0.132
|
Mouse Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
55 |
0.132
|
Fly |
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.132
|
Human Mouse Fly |
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
4 |
0.128
|
Human |
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.126
|
Fly |
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.125
|
Human Yeast Zebrafish Mouse Rat Fly |
|
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.125
|
|
|
|
cellular component movement
|
GO:0006928 |
335 |
0.124
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.124
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
33 |
0.124
|
Human Yeast |
|
|
positive regulation of signaling
|
GO:0023056 |
56 |
0.124
|
Human |
|
|
cellular component assembly
|
GO:0022607 |
170 |
0.124
|
Human |
|
|
regulation of circadian rhythm
|
GO:0042752 |
4 |
0.123
|
Mouse Fly |
|
|
anterior head development
|
GO:0097065 |
2 |
0.122
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
59 |
0.121
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
1 |
0.119
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
68 |
0.119
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
57 |
0.119
|
|
|
|
cell cycle
|
GO:0007049 |
93 |
0.118
|
Human Yeast |
|
|
protein localization
|
GO:0008104 |
40 |
0.118
|
Yeast |
|
|
regulation of cell cycle
|
GO:0051726 |
52 |
0.117
|
|
|
|
homeostatic process
|
GO:0042592 |
142 |
0.116
|
|
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.116
|
Human Yeast Zebrafish Mouse Rat Fly |
|
|
cell fate commitment
|
GO:0045165 |
99 |
0.115
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
102 |
0.115
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
274 |
0.115
|
|
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.115
|
Yeast |
|
|
neuron projection development
|
GO:0031175 |
180 |
0.113
|
|
|
|
protein modification process
|
GO:0036211 |
100 |
0.111
|
Human Yeast Zebrafish Mouse Rat Fly |
|
|
response to organic substance
|
GO:0010033 |
153 |
0.111
|
Fly |
|
|
cytoskeleton organization
|
GO:0007010 |
96 |
0.111
|
Human Yeast |
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.110
|
|
|
|
cellular protein metabolic process
|
GO:0044267 |
129 |
0.110
|
Human Yeast Zebrafish Mouse Rat Fly |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
3 |
0.109
|
|
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.109
|
Human Fly |
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
114 |
0.108
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
11 |
0.108
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
57 |
0.107
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
46 |
0.107
|
|
|
|
neuron projection guidance
|
GO:0097485 |
86 |
0.107
|
|
|
|
cell proliferation
|
GO:0008283 |
80 |
0.107
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
142 |
0.106
|
|
|
|
gland development
|
GO:0048732 |
143 |
0.106
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
77 |
0.105
|
|
|
|
microtubule based process
|
GO:0007017 |
60 |
0.105
|
Human Yeast |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.104
|
|
|
|
behavior
|
GO:0007610 |
74 |
0.103
|
Fly |
|
|
protein import
|
GO:0017038 |
3 |
0.103
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
161 |
0.103
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
25 |
0.102
|
|
|
|
nuclear transport
|
GO:0051169 |
4 |
0.102
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
65 |
0.102
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
29 |
0.102
|
|
|
|
sensory organ development
|
GO:0007423 |
393 |
0.102
|
Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
69 |
0.102
|
|
|
|
hindbrain development
|
GO:0030902 |
91 |
0.101
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
3 |
0.101
|
|
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.097
|
Human Mouse Fly |
|
|
cellular protein catabolic process
|
GO:0044257 |
4 |
0.096
|
Mouse Fly |
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.094
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
3 |
0.094
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
43 |
0.094
|
Human |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.094
|
|
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.093
|
Worm |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
3 |
0.093
|
Mouse Fly |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
34 |
0.092
|
Human |
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.092
|
Worm Fly |
|
|
single organism cell adhesion
|
GO:0098602 |
29 |
0.092
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
4 |
0.092
|
Mouse Fly |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
35 |
0.090
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
246 |
0.089
|
|
|
|
cell projection organization
|
GO:0030030 |
284 |
0.088
|
Fly |
|
|
phosphorylation
|
GO:0016310 |
69 |
0.087
|
Human Yeast Zebrafish Mouse Rat Fly |
|
|
multi organism process
|
GO:0051704 |
134 |
0.087
|
|
|
|
regulation of localization
|
GO:0032879 |
104 |
0.086
|
Fly |
|
|
muscle organ development
|
GO:0007517 |
101 |
0.086
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
78 |
0.086
|
|
|
|
neuron death
|
GO:0070997 |
21 |
0.086
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
57 |
0.086
|
|
|
|
camera type eye development
|
GO:0043010 |
222 |
0.085
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
98 |
0.085
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
130 |
0.084
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
59 |
0.083
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
24 |
0.083
|
Yeast |
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.083
|
Human Mouse Fly |
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.083
|
Human Yeast Zebrafish Mouse Rat Fly |
|
|
immune system development
|
GO:0002520 |
191 |
0.083
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
97 |
0.082
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
55 |
0.081
|
Fly |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
106 |
0.081
|
|
|
|
wnt signaling pathway involved in digestive tract morphogenesis
|
GO:0044333 |
4 |
0.081
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
152 |
0.081
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
4 |
0.079
|
|
|
|
skeletal system development
|
GO:0001501 |
181 |
0.079
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.079
|
|
|
|
specification of symmetry
|
GO:0009799 |
204 |
0.079
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
1 |
0.079
|
|
|
|
cell fate specification
|
GO:0001708 |
68 |
0.078
|
|
|
|
response to radiation
|
GO:0009314 |
51 |
0.078
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
4 |
0.078
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
18 |
0.078
|
Yeast |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
3 |
0.077
|
Mouse Fly |
|
|
rna processing
|
GO:0006396 |
25 |
0.076
|
Yeast |
|
|
regulation of sequestering of calcium ion
|
GO:0051282 |
4 |
0.074
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
33 |
0.072
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
30 |
0.072
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
200 |
0.072
|
Fly |
|
|
mediolateral intercalation
|
GO:0060031 |
3 |
0.071
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.071
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
87 |
0.071
|
|
|
|
system process
|
GO:0003008 |
185 |
0.070
|
Fly |
|
|
establishment of spindle localization
|
GO:0051293 |
12 |
0.070
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
53 |
0.070
|
Human |
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
1 |
0.069
|
|
|
|
axon guidance
|
GO:0007411 |
86 |
0.069
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
42 |
0.068
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
71 |
0.068
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
96 |
0.068
|
|
|
|
taxis
|
GO:0042330 |
109 |
0.067
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
4 |
0.066
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
178 |
0.066
|
Human Yeast |
|
|
epithelial cell differentiation
|
GO:0030855 |
116 |
0.066
|
Fly |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
2 |
0.066
|
Mouse Fly |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
3 |
0.066
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
79 |
0.065
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
3 |
0.065
|
Mouse Fly |
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
93 |
0.065
|
|
|
|
optic placode formation
|
GO:0001743 |
4 |
0.064
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
3 |
0.064
|
|
|
|
protein import into nucleus
|
GO:0006606 |
3 |
0.064
|
|
|
|
regulation of molecular function
|
GO:0065009 |
70 |
0.064
|
|
|
|
chromosome segregation
|
GO:0007059 |
12 |
0.064
|
Yeast |
|
|
nuclear import
|
GO:0051170 |
3 |
0.064
|
|
|
|
regulation of anterior head development
|
GO:2000742 |
2 |
0.063
|
|
|
|
connective tissue development
|
GO:0061448 |
99 |
0.063
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
76 |
0.062
|
|
|
|
chemotaxis
|
GO:0006935 |
104 |
0.061
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
163 |
0.061
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
25 |
0.060
|
Yeast |
|
|
hepatocyte proliferation
|
GO:0072574 |
2 |
0.060
|
|
|
|
liver development
|
GO:0001889 |
96 |
0.060
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
34 |
0.060
|
|
|
|
membrane invagination
|
GO:0010324 |
1 |
0.060
|
|
|
|
spindle assembly
|
GO:0051225 |
2 |
0.059
|
Human |
|
|
spindle localization
|
GO:0051653 |
12 |
0.059
|
|
|
|
specification of axis polarity
|
GO:0065001 |
4 |
0.059
|
|
|
|
cognition
|
GO:0050890 |
1 |
0.059
|
|
|
|
nuclear division
|
GO:0000280 |
23 |
0.059
|
Yeast |
|
|
autophagy
|
GO:0006914 |
4 |
0.058
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
3 |
0.058
|
|
|
|
regulation of wnt signaling pathway involved in digestive tract morphogenesis
|
GO:2000056 |
2 |
0.058
|
|
|
|
regulation of response to stress
|
GO:0080134 |
36 |
0.057
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
12 |
0.057
|
|
|
|
brain development
|
GO:0007420 |
293 |
0.057
|
|
|
|
wound healing
|
GO:0042060 |
90 |
0.057
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
55 |
0.057
|
|
|
|
phagocytosis engulfment
|
GO:0006911 |
1 |
0.057
|
|
|
|
hepatic duct development
|
GO:0061011 |
2 |
0.056
|
|
|
|
regulation of locomotion
|
GO:0040012 |
55 |
0.056
|
|
|
|
cation homeostasis
|
GO:0055080 |
33 |
0.056
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
52 |
0.055
|
Human Mouse Fly |
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.055
|
Human Mouse Worm Fly |
|
|
immune system process
|
GO:0002376 |
241 |
0.055
|
|
|
|
single organism nuclear import
|
GO:1902593 |
3 |
0.055
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
3 |
0.055
|
|
|
|
adult behavior
|
GO:0030534 |
2 |
0.054
|
Fly |
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
71 |
0.052
|
|
|
|
establishment of mitotic spindle localization
|
GO:0040001 |
12 |
0.052
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.052
|
Worm |
|
|
macromolecular complex subunit organization
|
GO:0043933 |
74 |
0.052
|
Human |
|
|
pancreas development
|
GO:0031016 |
84 |
0.052
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
1 |
0.052
|
Mouse Fly |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
3 |
0.051
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
4 |
0.051
|
|
|
|
response to uv
|
GO:0009411 |
3 |
0.051
|
|
|
|
regulation of wnt signaling pathway calcium modulating pathway
|
GO:0008591 |
3 |
0.051
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
1 |
0.050
|
|
|
|
convergent extension
|
GO:0060026 |
118 |
0.050
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
37 |
0.050
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
20 |
0.050
|
|
|
|
response to alkaloid
|
GO:0043279 |
2 |
0.050
|
Fly |
|
|
circadian regulation of gene expression
|
GO:0032922 |
8 |
0.050
|
Mouse |
|
|
negative regulation of cell division
|
GO:0051782 |
4 |
0.050
|
|
|
|
axonogenesis
|
GO:0007409 |
152 |
0.049
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
2 |
0.049
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
86 |
0.049
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
21 |
0.048
|
Yeast |
|
|
positive regulation of cytokine production
|
GO:0001819 |
2 |
0.048
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
43 |
0.048
|
Human |
|
|
heart looping
|
GO:0001947 |
94 |
0.048
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
4 |
0.048
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
3 |
0.048
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
18 |
0.048
|
Human |
|
|
positive regulation of ras protein signal transduction
|
GO:0046579 |
1 |
0.047
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
90 |
0.047
|
|
|
|
regulation of wound healing
|
GO:0061041 |
2 |
0.047
|
|
|
|
negative regulation of sequestering of calcium ion
|
GO:0051283 |
4 |
0.046
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
3 |
0.046
|
|
|
|
thrombocyte differentiation
|
GO:0002574 |
4 |
0.046
|
|
|
|
somitogenesis
|
GO:0001756 |
87 |
0.046
|
|
|
|
limbic system development
|
GO:0021761 |
16 |
0.045
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
4 |
0.045
|
|
|
|
regulation of growth
|
GO:0040008 |
42 |
0.045
|
Worm Fly |
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
90 |
0.045
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
86 |
0.045
|
|
|
|
female meiotic division
|
GO:0007143 |
2 |
0.045
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
3 |
0.045
|
|
|
|
axon development
|
GO:0061564 |
166 |
0.044
|
|
|
|
regulation of binding
|
GO:0051098 |
3 |
0.044
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
2 |
0.044
|
|
|
|
germ line stem cell maintenance
|
GO:0030718 |
2 |
0.043
|
|
|
|
single organism cellular localization
|
GO:1902580 |
46 |
0.043
|
|
|
|
regulation of cell size
|
GO:0008361 |
29 |
0.043
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
1 |
0.043
|
|
|
|
apoptotic process involved in development
|
GO:1902742 |
2 |
0.042
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
64 |
0.042
|
Yeast |
|
|
forebrain development
|
GO:0030900 |
96 |
0.042
|
|
|
|
cell cell signaling
|
GO:0007267 |
52 |
0.042
|
Fly |
|
|
female sex differentiation
|
GO:0046660 |
4 |
0.042
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
1 |
0.041
|
|
|
|
axis specification
|
GO:0009798 |
43 |
0.041
|
|
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.041
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
204 |
0.041
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
68 |
0.041
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
7 |
0.041
|
|
|
|
cytokinesis
|
GO:0000910 |
3 |
0.041
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
65 |
0.040
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
3 |
0.040
|
|
|
|
positive regulation of transport
|
GO:0051050 |
2 |
0.040
|
|
|
|
response to endogenous stimulus
|
GO:0009719 |
83 |
0.040
|
Fly |
|
|
spinal cord anterior posterior patterning
|
GO:0021512 |
1 |
0.040
|
|
|
|
stem cell development
|
GO:0048864 |
82 |
0.039
|
|
|
|
mesenchyme development
|
GO:0060485 |
127 |
0.039
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
60 |
0.038
|
Fly |
|
|
cytosolic calcium ion transport
|
GO:0060401 |
3 |
0.038
|
|
|
|
establishment of endothelial barrier
|
GO:0061028 |
3 |
0.038
|
|
|
|
mitotic cell cycle embryonic
|
GO:0045448 |
2 |
0.038
|
|
|
|
phagocytosis
|
GO:0006909 |
3 |
0.038
|
|
|
|
cortical cytoskeleton organization
|
GO:0030865 |
1 |
0.037
|
|
|
|
eye field cell fate commitment involved in camera type eye formation
|
GO:0060898 |
3 |
0.037
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
17 |
0.037
|
|
|
|
transport
|
GO:0006810 |
220 |
0.037
|
Yeast Fly |
|
|
sequestering of metal ion
|
GO:0051238 |
3 |
0.037
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
55 |
0.037
|
|
|
|
oogenesis
|
GO:0048477 |
14 |
0.037
|
|
|
|
muscle tissue development
|
GO:0060537 |
110 |
0.037
|
|
|
|
segmentation
|
GO:0035282 |
97 |
0.036
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
4 |
0.036
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
15 |
0.036
|
Mouse Fly |
|
|
regulation of cell migration
|
GO:0030334 |
40 |
0.036
|
|
|
|
ear development
|
GO:0043583 |
127 |
0.036
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
30 |
0.036
|
|
|
|
regulation of mitosis
|
GO:0007088 |
9 |
0.036
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
71 |
0.036
|
|
|
|
kupffer s vesicle development
|
GO:0070121 |
50 |
0.036
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
68 |
0.035
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
55 |
0.035
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
20 |
0.035
|
|
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.035
|
|
|
|
organic substance transport
|
GO:0071702 |
58 |
0.035
|
Fly |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
48 |
0.035
|
Human |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
1 |
0.034
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
39 |
0.034
|
|
|
|
response to wounding
|
GO:0009611 |
116 |
0.034
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
18 |
0.034
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
2 |
0.034
|
Fly |
|
|
somite development
|
GO:0061053 |
96 |
0.034
|
|
|
|
regulation of cell growth
|
GO:0001558 |
29 |
0.034
|
Fly |
|
|
response to organic cyclic compound
|
GO:0014070 |
51 |
0.034
|
Fly |
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
21 |
0.034
|
Human |
|
|
macromolecule localization
|
GO:0033036 |
54 |
0.033
|
Yeast Fly |
|
|
epithelial cell development
|
GO:0002064 |
42 |
0.033
|
|
|
|
mitochondrion organization
|
GO:0007005 |
4 |
0.033
|
|
|
|
cellular localization
|
GO:0051641 |
97 |
0.033
|
Yeast Fly |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
38 |
0.033
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
42 |
0.033
|
|
|
|
reproductive process
|
GO:0022414 |
40 |
0.033
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
80 |
0.033
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
2 |
0.033
|
|
|
|
fertilization
|
GO:0009566 |
3 |
0.033
|
|
|
|
dorsal ventral axis specification
|
GO:0009950 |
14 |
0.033
|
|
|
|
establishment of mitotic spindle orientation
|
GO:0000132 |
10 |
0.033
|
|
|
|
single organism reproductive process
|
GO:0044702 |
40 |
0.032
|
|
|
|
protein phosphorylation
|
GO:0006468 |
47 |
0.032
|
Human Yeast Zebrafish Mouse Rat Fly |
|
|
rhythmic process
|
GO:0048511 |
21 |
0.032
|
Mouse Fly |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
2 |
0.032
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
4 |
0.032
|
|
|
|
heart morphogenesis
|
GO:0003007 |
156 |
0.032
|
|
|
|
regulation of fibroblast growth factor receptor signaling pathway
|
GO:0040036 |
20 |
0.032
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
22 |
0.032
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
191 |
0.031
|
|
|
|
regulation of autophagy
|
GO:0010506 |
3 |
0.031
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
2 |
0.031
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
50 |
0.031
|
|
|
|
gamete generation
|
GO:0007276 |
33 |
0.031
|
|
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
45 |
0.031
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
86 |
0.031
|
Fly |
|
|
organelle localization
|
GO:0051640 |
49 |
0.031
|
|
|
|
hemopoiesis
|
GO:0030097 |
183 |
0.031
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
26 |
0.031
|
Human |
|
|
striated muscle tissue development
|
GO:0014706 |
110 |
0.031
|
|
|
|
lipid storage
|
GO:0019915 |
1 |
0.031
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
3 |
0.030
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
3 |
0.030
|
|
|
|
receptor internalization
|
GO:0031623 |
2 |
0.030
|
|
|
|
calcium ion transport
|
GO:0006816 |
18 |
0.030
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
16 |
0.030
|
|
|
|
ion transport
|
GO:0006811 |
114 |
0.029
|
|
|
|
cellular response to starvation
|
GO:0009267 |
1 |
0.029
|
|
|
|
regulation of cell motility
|
GO:2000145 |
46 |
0.029
|
|
|
|
kidney development
|
GO:0001822 |
92 |
0.029
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
48 |
0.029
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
23 |
0.029
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
50 |
0.029
|
Worm |
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
4 |
0.029
|
|
|
|
cellular component disassembly
|
GO:0022411 |
1 |
0.029
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
4 |
0.029
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
4 |
0.028
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
2 |
0.028
|
|
|
|
membrane organization
|
GO:0061024 |
21 |
0.028
|
|
|
|
nuclear migration
|
GO:0007097 |
3 |
0.028
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
2 |
0.028
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
9 |
0.028
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
2 |
0.028
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
36 |
0.028
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.027
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
2 |
0.027
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
3 |
0.027
|
Yeast |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
148 |
0.027
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
139 |
0.027
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
27 |
0.027
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
23 |
0.027
|
Human Mouse Fly |
|
|
protein polyubiquitination
|
GO:0000209 |
4 |
0.026
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
2 |
0.026
|
|
|
|
regulation of protein transport
|
GO:0051223 |
3 |
0.026
|
|
|
|
protein complex localization
|
GO:0031503 |
1 |
0.026
|
|
|
|
proteolysis
|
GO:0006508 |
38 |
0.026
|
Mouse Fly |
|
|
establishment of localization in cell
|
GO:0051649 |
77 |
0.026
|
Yeast Fly |
|
|
gall bladder development
|
GO:0061010 |
1 |
0.026
|
|
|
|
positive regulation of small gtpase mediated signal transduction
|
GO:0051057 |
1 |
0.026
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
15 |
0.026
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
44 |
0.026
|
|
|
|
neural tube patterning
|
GO:0021532 |
33 |
0.026
|
|
|
|
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway
|
GO:0022002 |
1 |
0.026
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
74 |
0.026
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
44 |
0.026
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
9 |
0.025
|
|
|
|
cortical actin cytoskeleton organization
|
GO:0030866 |
1 |
0.025
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
5 |
0.025
|
Yeast |
|
|
regulation of tube size
|
GO:0035150 |
2 |
0.025
|
|
|
|
skeletal muscle tissue development
|
GO:0007519 |
67 |
0.025
|
|
|
|
spermatid differentiation
|
GO:0048515 |
2 |
0.025
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
2 |
0.025
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
2 |
0.025
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
2 |
0.025
|
Mouse Fly |
|
|
organic substance catabolic process
|
GO:1901575 |
28 |
0.025
|
Mouse Fly |
|
|
regulation of transport
|
GO:0051049 |
45 |
0.025
|
Fly |
|
|
cellular amine metabolic process
|
GO:0044106 |
2 |
0.025
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
2 |
0.025
|
|
|
|
mapk cascade
|
GO:0000165 |
18 |
0.025
|
|
|
|
gastrulation with mouth forming second
|
GO:0001702 |
44 |
0.025
|
|
|
|
unidimensional cell growth
|
GO:0009826 |
5 |
0.025
|
|
|
|
body morphogenesis
|
GO:0010171 |
16 |
0.025
|
Worm |
|
|
dorsal convergence
|
GO:0060030 |
14 |
0.025
|
|
|
|
regulation of cell development
|
GO:0060284 |
100 |
0.025
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
1 |
0.025
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
1 |
0.025
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
2 |
0.025
|
|
|
|
axon extension
|
GO:0048675 |
45 |
0.024
|
|
