Danio rerio

30 known processes

ctnnb1

catenin (cadherin-associated protein), beta 1

(Aliases: ctnnb,wu:fb73e10,wu:fk25h01,id:ibd2058,wu:fi81c06)

ctnnb1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
biosynthetic process GO:0009058 294 0.856
Human Mouse Worm Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.765
Human Mouse
larval development GO:0002164 2 0.694
Worm Fly
organic substance biosynthetic process GO:1901576 289 0.664
Human Mouse Worm Fly
morphogenesis of an epithelium GO:0002009 333 0.646
macromolecule glycosylation GO:0043413 9 0.643
cellular component movement GO:0006928 335 0.622
Mouse Worm
positive regulation of biological process GO:0048518 253 0.593
Human Mouse Worm Fly
positive regulation of cellular process GO:0048522 201 0.535
Human Mouse Worm Fly
regulation of cellular metabolic process GO:0031323 320 0.535
Human Mouse Worm Fly
ameboidal type cell migration GO:0001667 143 0.521
Worm
protein glycosylation GO:0006486 9 0.519
regulation of multicellular organismal process GO:0051239 277 0.518
Human Zebrafish Mouse Worm Fly
heterocycle biosynthetic process GO:0018130 215 0.517
Human Mouse Worm Fly
cell morphogenesis GO:0000902 289 0.514
Human Mouse Fly
organelle organization GO:0006996 227 0.514
Human Mouse Worm
epithelial cell morphogenesis GO:0003382 2 0.512
Mouse
nitrogen compound metabolic process GO:0006807 319 0.495
Human Mouse Worm Fly
embryonic heart tube development GO:0035050 133 0.485
Mouse
axon development GO:0061564 166 0.467
regulation of primary metabolic process GO:0080090 311 0.457
Human Mouse Worm Fly
regulation of metabolic process GO:0019222 359 0.453
Human Mouse Worm Fly
response to wounding GO:0009611 116 0.451
glycoprotein biosynthetic process GO:0009101 21 0.432
Human
sensory organ development GO:0007423 393 0.430
Mouse Fly
cell projection morphogenesis GO:0048858 244 0.418
sexual reproduction GO:0019953 36 0.411
Mouse Worm Fly
cellular component morphogenesis GO:0032989 336 0.392
Human Mouse Fly
heart development GO:0007507 313 0.380
Zebrafish Mouse Fly
single organism localization GO:1902578 225 0.379
Human Mouse Fly
regulation of mrna splicing via spliceosome GO:0048024 3 0.370
localization of cell GO:0051674 244 0.368
Mouse Worm
positive regulation of catabolic process GO:0009896 4 0.358
regulation of mrna processing GO:0050684 3 0.357
cellular protein metabolic process GO:0044267 129 0.338
Human Worm
cell cycle GO:0007049 93 0.332
Human Mouse Worm
dorsal ventral pattern formation GO:0009953 125 0.330
neuron development GO:0048666 262 0.312
regulation of organelle organization GO:0033043 29 0.306
Human Mouse Worm
axonogenesis GO:0007409 152 0.305
regulation of response to stimulus GO:0048583 269 0.304
Zebrafish Mouse
cellular biosynthetic process GO:0044249 286 0.294
Human Mouse Worm Fly
determination of left right symmetry GO:0007368 179 0.291
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.291
axon guidance GO:0007411 86 0.284
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.274
cell motility GO:0048870 244 0.274
Mouse Worm
macromolecule biosynthetic process GO:0009059 227 0.272
Human Mouse Worm Fly
carbohydrate derivative biosynthetic process GO:1901137 43 0.270
Human
gene expression GO:0010467 252 0.265
Human Mouse Worm Fly
glycoprotein metabolic process GO:0009100 23 0.264
Human
cell cycle process GO:0022402 53 0.262
Human Mouse Worm
regulation of macromolecule biosynthetic process GO:0010556 225 0.261
Human Mouse Worm Fly
aromatic compound biosynthetic process GO:0019438 217 0.253
Human Mouse Worm Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.244
Human Mouse Worm Fly
cellular protein catabolic process GO:0044257 4 0.242
nuclear import GO:0051170 3 0.236
anterior posterior pattern specification GO:0009952 152 0.235
Mouse
protein import GO:0017038 3 0.234
response to chemical GO:0042221 320 0.230
Human Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.228
Human Mouse Worm Fly
protein targeting to nucleus GO:0044744 3 0.228
cellular component biogenesis GO:0044085 178 0.227
Human Fly
neuron projection morphogenesis GO:0048812 161 0.227
organic cyclic compound biosynthetic process GO:1901362 223 0.223
Human Mouse Worm Fly
regulation of protein metabolic process GO:0051246 56 0.222
Human Worm
positive regulation of cellular catabolic process GO:0031331 3 0.222
regulation of rna metabolic process GO:0051252 224 0.218
Human Mouse Worm Fly
positive regulation of cellular metabolic process GO:0031325 94 0.217
Human Mouse Worm Fly
positive regulation of notch signaling pathway GO:0045747 3 0.210
medial fin development GO:0033338 16 0.205
response to stress GO:0006950 263 0.204
somite development GO:0061053 96 0.203
negative regulation of cellular metabolic process GO:0031324 77 0.199
Human Mouse
positive regulation of stress activated mapk cascade GO:0032874 3 0.195
regulation of developmental process GO:0050793 247 0.195
Human Zebrafish Mouse Worm Fly
positive regulation of metabolic process GO:0009893 108 0.192
Human Mouse Worm Fly
mitotic cell cycle GO:0000278 64 0.187
Mouse Worm
dorsal convergence GO:0060030 14 0.185
regulation of signaling GO:0023051 235 0.180
Zebrafish Mouse Fly
regulation of cellular component organization GO:0051128 86 0.178
Human Mouse Worm Fly
positive regulation of jnk cascade GO:0046330 3 0.177
regulation of biological quality GO:0065008 263 0.175
Mouse Fly
adherens junction maintenance GO:0034334 2 0.174
regulation of establishment of protein localization GO:0070201 4 0.174
multi organism process GO:0051704 134 0.171
Mouse Worm Fly
glycosylation GO:0070085 11 0.171
mesenchyme development GO:0060485 127 0.166
Human Mouse
stem cell differentiation GO:0048863 117 0.161
Human Fly
regulation of apoptotic process GO:0042981 98 0.161
Human Mouse
single organism nuclear import GO:1902593 3 0.160
carbohydrate derivative metabolic process GO:1901135 61 0.160
Human
specification of axis polarity GO:0065001 4 0.158
Worm
eye development GO:0001654 277 0.156
Mouse Fly
cytoskeleton organization GO:0007010 96 0.156
Human Worm
skeletal system development GO:0001501 181 0.156
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.154
Human Mouse Worm Fly
reproductive process GO:0022414 40 0.154
Mouse Worm Fly
regulation of protein binding GO:0043393 3 0.154
regulation of cell morphogenesis GO:0022604 42 0.151
Human Fly
regulation of macromolecule metabolic process GO:0060255 317 0.151
Human Mouse Worm Fly
germ line stem cell maintenance GO:0030718 2 0.151
nuclear division GO:0000280 23 0.150
establishment of protein localization to organelle GO:0072594 4 0.149
single organism metabolic process GO:0044710 217 0.149
Human Mouse
cell part morphogenesis GO:0032990 246 0.148
cartilage development GO:0051216 96 0.147
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.146
Mouse Worm Fly
protein import into nucleus GO:0006606 3 0.146
cell recognition GO:0008037 19 0.146
multicellular organism growth GO:0035264 4 0.141
meiotic nuclear division GO:0007126 4 0.138
cell death GO:0008219 121 0.137
Human Mouse Fly
stem cell development GO:0048864 82 0.137
Human Fly
stem cell maintenance GO:0019827 4 0.135
Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.129
maintenance of location GO:0051235 4 0.125
positive regulation of jun kinase activity GO:0043507 2 0.125
cell surface receptor signaling pathway GO:0007166 325 0.125
Human Zebrafish Mouse Worm Fly
nucleic acid metabolic process GO:0090304 244 0.124
Human Mouse Worm Fly
axonal fasciculation GO:0007413 11 0.124
regulation of epithelial cell proliferation GO:0050678 3 0.123
Mouse
phagocytosis GO:0006909 3 0.123
positive regulation of macromolecule metabolic process GO:0010604 93 0.118
Human Mouse Worm Fly
spermatid differentiation GO:0048515 2 0.116
skeletal system morphogenesis GO:0048705 102 0.115
Mouse
regulation of protein catabolic process GO:0042176 1 0.115
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.114
generation of neurons GO:0048699 385 0.114
Mouse Fly
male meiosis GO:0007140 2 0.113
segmentation GO:0035282 97 0.111
regulation of cellular biosynthetic process GO:0031326 245 0.109
Human Mouse Worm Fly
regulation of nervous system development GO:0051960 90 0.109
Mouse
cellular localization GO:0051641 97 0.108
Human Mouse Fly
mesenchymal cell development GO:0014031 78 0.107
Human
optic placode formation GO:0001743 4 0.107
ubiquitin dependent protein catabolic process GO:0006511 3 0.107
rna metabolic process GO:0016070 219 0.105
Human Mouse Worm Fly
single organism organelle organization GO:1902589 199 0.105
Human Mouse Worm
convergent extension GO:0060026 118 0.105
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.103
negative regulation of signaling GO:0023057 96 0.102
Zebrafish Mouse Fly
aging GO:0007568 2 0.099
adherens junction organization GO:0034332 4 0.098
Human Mouse Fly
regulation of multicellular organismal development GO:2000026 223 0.098
Human Zebrafish Mouse Worm Fly
response to organic substance GO:0010033 153 0.098
Human Mouse
regulation of multicellular organism growth GO:0040014 4 0.097
nucleocytoplasmic transport GO:0006913 4 0.097
chemotaxis GO:0006935 104 0.096
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.095
Human Mouse Worm Fly
camera type eye morphogenesis GO:0048593 108 0.094
Mouse
regulation of transcription dna templated GO:0006355 213 0.093
Human Mouse Worm Fly
negative regulation of programmed cell death GO:0043069 58 0.093
Human Mouse
regulation of cellular response to growth factor stimulus GO:0090287 35 0.093
Mouse
nucleic acid templated transcription GO:0097659 181 0.092
Human Mouse Worm Fly
rho protein signal transduction GO:0007266 5 0.091
tube morphogenesis GO:0035239 349 0.091
Human Mouse Worm Fly
regulation of stem cell proliferation GO:0072091 2 0.091
Mouse
neuron projection development GO:0031175 180 0.090
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.090
Human Mouse Worm Fly
cell fate commitment GO:0045165 99 0.089
Mouse Worm Fly
cell migration GO:0016477 237 0.088
Mouse Worm
oxoacid metabolic process GO:0043436 31 0.088
Human
developmental growth GO:0048589 166 0.086
Fly
reproduction GO:0000003 40 0.085
Mouse Worm Fly
cellular response to chemical stimulus GO:0070887 157 0.085
Human Mouse
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.085
protein modification process GO:0036211 100 0.084
Human Worm
nuclear transport GO:0051169 4 0.083
spermatogenesis GO:0007283 7 0.083
signal transduction GO:0007165 455 0.082
Human Zebrafish Mouse Worm Fly
regulation of binding GO:0051098 3 0.082
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.082
embryonic organ morphogenesis GO:0048562 274 0.081
Mouse
camera type eye development GO:0043010 222 0.081
Mouse
keratinocyte differentiation GO:0030216 0 0.080
modification dependent protein catabolic process GO:0019941 3 0.080
determination of heart left right asymmetry GO:0061371 117 0.079
regionalization GO:0003002 274 0.079
brain development GO:0007420 293 0.078
Mouse
neural tube development GO:0021915 62 0.078
embryonic skeletal system development GO:0048706 97 0.077
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.077
Human Mouse Worm Fly
mitotic cell cycle embryonic GO:0045448 2 0.076
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.076
Human Mouse
neuron projection guidance GO:0097485 86 0.075
determination of bilateral symmetry GO:0009855 204 0.075
extrinsic apoptotic signaling pathway GO:0097191 3 0.074
response to external stimulus GO:0009605 264 0.073
protein localization to nucleus GO:0034504 3 0.073
heart looping GO:0001947 94 0.072
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.071
Human Mouse Worm Fly
compound eye development GO:0048749 2 0.071
Fly
connective tissue development GO:0061448 99 0.071
Mouse
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.070
regeneration GO:0031099 91 0.070
organelle localization GO:0051640 49 0.070
Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.070
Mouse
transport GO:0006810 220 0.069
Human Mouse Worm
ras protein signal transduction GO:0007265 7 0.069
Worm
positive regulation of multicellular organismal process GO:0051240 52 0.069
Human Mouse Worm Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.069
Human Mouse Worm Fly
neuron recognition GO:0008038 18 0.068
protein catabolic process GO:0030163 7 0.067
cellular protein modification process GO:0006464 100 0.067
Human Worm
small gtpase mediated signal transduction GO:0007264 8 0.067
Worm
establishment of epithelial cell polarity GO:0090162 2 0.067
intracellular signal transduction GO:0035556 85 0.067
Mouse Worm
defense response GO:0006952 47 0.067
regulation of nucleocytoplasmic transport GO:0046822 2 0.066
regulation of transport GO:0051049 45 0.066
Human
negative regulation of biological process GO:0048519 304 0.066
Human Zebrafish Mouse Worm Fly
single organism transport GO:0044765 206 0.065
Human Mouse
gamete generation GO:0007276 33 0.065
Mouse Fly
tissue regeneration GO:0042246 74 0.064
regulation of receptor mediated endocytosis GO:0048259 4 0.063
regulation of cell development GO:0060284 100 0.063
Human Mouse
response to growth factor GO:0070848 39 0.063
Human Mouse
positive regulation of cell cycle GO:0045787 3 0.063
rna biosynthetic process GO:0032774 181 0.062
Human Mouse Worm Fly
cellular amino acid metabolic process GO:0006520 7 0.062
negative regulation of developmental process GO:0051093 65 0.062
Zebrafish Mouse Fly
posttranscriptional regulation of gene expression GO:0010608 14 0.062
regulation of gene expression GO:0010468 265 0.062
Human Mouse Worm Fly
system process GO:0003008 185 0.062
Fly
epithelial cell differentiation GO:0030855 116 0.061
Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.060
Human Mouse Worm Fly
regulation of response to stress GO:0080134 36 0.060
negative regulation of transcription dna templated GO:0045892 45 0.060
Human Mouse
regulation of locomotion GO:0040012 55 0.060
Worm
organic cyclic compound metabolic process GO:1901360 301 0.059
Human Mouse Worm Fly
cell projection organization GO:0030030 284 0.059
positive regulation of cellular biosynthetic process GO:0031328 68 0.059
Human Mouse Worm Fly
regulation of protein targeting GO:1903533 2 0.057
germ cell development GO:0007281 22 0.057
Mouse Fly
regulation of cell death GO:0010941 103 0.057
Human Mouse
carboxylic acid metabolic process GO:0019752 22 0.056
cellular ketone metabolic process GO:0042180 11 0.056
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.056
epithelial tube morphogenesis GO:0060562 148 0.055
Human Mouse Fly
spermatid development GO:0007286 2 0.055
programmed cell death GO:0012501 119 0.055
Human Mouse Fly
establishment of apical basal cell polarity GO:0035089 2 0.055
wound healing GO:0042060 90 0.053
organic acid metabolic process GO:0006082 31 0.053
Human
ion homeostasis GO:0050801 41 0.052
cellular response to lipid GO:0071396 39 0.052
regulation of growth GO:0040008 42 0.052
regulation of rho protein signal transduction GO:0035023 2 0.051
regulation of anatomical structure morphogenesis GO:0022603 130 0.051
Human Mouse Fly
cellular response to extracellular stimulus GO:0031668 2 0.050
regulation of nitrogen compound metabolic process GO:0051171 251 0.050
Human Mouse Worm Fly
protein metabolic process GO:0019538 183 0.049
Human Worm
adult behavior GO:0030534 2 0.049
response to other organism GO:0051707 97 0.049
cellular response to nutrient levels GO:0031669 2 0.049
notch signaling pathway GO:0007219 35 0.049
mesoderm development GO:0007498 88 0.048
negative regulation of cellular process GO:0048523 283 0.048
Human Zebrafish Mouse Fly
cellular macromolecule metabolic process GO:0044260 391 0.048
Human Mouse Worm Fly
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.047
muscle contraction GO:0006936 18 0.047
cellular component maintenance GO:0043954 3 0.047
retina development in camera type eye GO:0060041 146 0.047
positive regulation of chromatin modification GO:1903310 1 0.047
regulation of cellular amine metabolic process GO:0033238 0 0.047
regulation of intracellular protein transport GO:0033157 3 0.046
regulation of synapse assembly GO:0051963 3 0.046
negative regulation of response to stimulus GO:0048585 104 0.046
Zebrafish Mouse
positive regulation of chromosome organization GO:2001252 1 0.045
heart morphogenesis GO:0003007 156 0.045
Mouse Fly
regulation of mitotic cell cycle GO:0007346 25 0.045
Mouse
negative regulation of cellular biosynthetic process GO:0031327 55 0.045
Human Mouse
regulation of cell differentiation GO:0045595 142 0.045
Human Mouse Worm Fly
regulation of organ morphogenesis GO:2000027 35 0.045
Mouse Fly
embryonic eye morphogenesis GO:0048048 30 0.045
negative regulation of mrna metabolic process GO:1903312 3 0.044
specification of symmetry GO:0009799 204 0.043
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.043
negative regulation of metabolic process GO:0009892 86 0.043
Human Mouse
cognition GO:0050890 1 0.043
Fly
primary neural tube formation GO:0014020 1 0.043
cellular response to acid chemical GO:0071229 8 0.042
protein localization GO:0008104 40 0.042
Human Mouse Worm Fly
small molecule metabolic process GO:0044281 77 0.042
Human
positive regulation of transport GO:0051050 2 0.042
embryonic heart tube morphogenesis GO:0003143 108 0.042
cellular response to starvation GO:0009267 1 0.042
regulation of signal transduction GO:0009966 225 0.042
Zebrafish Mouse
cell junction maintenance GO:0034331 2 0.041
regulation of nucleic acid templated transcription GO:1903506 213 0.041
Human Mouse Worm Fly
muscle structure development GO:0061061 196 0.041
Mouse
regulation of cellular protein metabolic process GO:0032268 52 0.041
Human Worm
protein o linked glycosylation GO:0006493 4 0.041
cell adhesion GO:0007155 40 0.040
Human Mouse Worm Fly
ion transport GO:0006811 114 0.040
Human
embryonic organ development GO:0048568 381 0.040
Mouse
alternative mrna splicing via spliceosome GO:0000380 1 0.040
cellular response to retinoic acid GO:0071300 1 0.040
axis specification GO:0009798 43 0.040
cell cell adhesion involved in gastrulation GO:0070586 4 0.039
regulation of stem cell differentiation GO:2000736 4 0.039
Human Fly
locomotion GO:0040011 313 0.038
Mouse Worm
body morphogenesis GO:0010171 16 0.038
Worm
actin filament based movement GO:0030048 1 0.038
regulation of biosynthetic process GO:0009889 250 0.038
Human Mouse Worm Fly
organonitrogen compound metabolic process GO:1901564 74 0.038
wnt signaling pathway GO:0016055 80 0.038
Human Zebrafish Mouse Worm Fly
ossification GO:0001503 23 0.037
Mouse
neuron differentiation GO:0030182 353 0.037
Fly
lamellipodium assembly GO:0030032 1 0.037
regulation of cellular amino acid metabolic process GO:0006521 0 0.037
canonical wnt signaling pathway GO:0060070 48 0.037
Human Mouse Fly
somitogenesis GO:0001756 87 0.036
blood vessel morphogenesis GO:0048514 216 0.036
Mouse
negative regulation of calcium dependent cell cell adhesion GO:0046588 1 0.036
proteasomal protein catabolic process GO:0010498 2 0.036
polarized epithelial cell differentiation GO:0030859 4 0.034
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.034
Worm
hepatocyte proliferation GO:0072574 2 0.034
synaptic growth at neuromuscular junction GO:0051124 2 0.034
taxis GO:0042330 109 0.034
actin polymerization or depolymerization GO:0008154 2 0.034
regulation of establishment of planar polarity GO:0090175 4 0.034
growth GO:0040007 174 0.033
Fly
regulation of localization GO:0032879 104 0.033
Human Worm
central nervous system development GO:0007417 387 0.033
Mouse
regulation of reproductive process GO:2000241 4 0.033
Mouse
cellular response to organic substance GO:0071310 105 0.033
Human Mouse
positive regulation of rna biosynthetic process GO:1902680 57 0.033
Human Mouse Worm Fly
anatomical structure arrangement GO:0048532 2 0.033
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.032
positive regulation of mrna metabolic process GO:1903313 2 0.032
regulation of calcium dependent cell cell adhesion GO:0046586 1 0.032
regulation of cytoplasmic transport GO:1903649 4 0.032
eye morphogenesis GO:0048592 144 0.032
Mouse Fly
blood circulation GO:0008015 87 0.032
establishment of organelle localization GO:0051656 45 0.032
Mouse
desmosome assembly GO:0002159 2 0.032
erk1 and erk2 cascade GO:0070371 4 0.032
positive regulation of developmental process GO:0051094 50 0.031
Human Mouse Worm Fly
regulation of epithelial to mesenchymal transition GO:0010717 3 0.031
Human
chordate embryonic development GO:0043009 271 0.031
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 1 0.031
regulation of cell shape GO:0008360 1 0.031
Fly
regulation of intracellular signal transduction GO:1902531 57 0.031
Mouse
regulation of protein localization to nucleus GO:1900180 2 0.031
single organism reproductive process GO:0044702 40 0.030
Mouse Worm Fly
cell division GO:0051301 20 0.030
regulation of cellular protein catabolic process GO:1903362 1 0.030
cell growth GO:0016049 57 0.030
cellular response to biotic stimulus GO:0071216 3 0.030
macromolecular complex assembly GO:0065003 35 0.030
nucleobase containing compound metabolic process GO:0006139 274 0.030
Human Mouse Worm Fly
negative regulation of nucleic acid templated transcription GO:1903507 45 0.030
Human Mouse
cellular amine metabolic process GO:0044106 2 0.029
lamellipodium organization GO:0097581 1 0.029
organic substance catabolic process GO:1901575 28 0.029
response to biotic stimulus GO:0009607 97 0.029
fertilization GO:0009566 3 0.029
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.029
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.029
regulation of synapse organization GO:0050807 3 0.029
positive regulation of signaling GO:0023056 56 0.028
Mouse
regulation of jun kinase activity GO:0043506 3 0.028
ectoderm development GO:0007398 9 0.028
regulation of cardiac muscle contraction GO:0055117 2 0.028
regulation of purine nucleotide catabolic process GO:0033121 2 0.028
regulation of protein ubiquitination GO:0031396 3 0.028
metal ion homeostasis GO:0055065 26 0.028
release of sequestered calcium ion into cytosol GO:0051209 3 0.027
establishment of mitotic spindle localization GO:0040001 12 0.027
embryonic camera type eye morphogenesis GO:0048596 19 0.027
regulation of catalytic activity GO:0050790 55 0.027
Mouse Worm
amine metabolic process GO:0009308 2 0.027
regulation of cell proliferation GO:0042127 37 0.027
Human Mouse
positive regulation of protein metabolic process GO:0051247 23 0.027
Human Worm
activation of jun kinase activity GO:0007257 2 0.026
cell proliferation GO:0008283 80 0.026
Human Mouse Fly
regulation of protein transport GO:0051223 3 0.026
epiboly GO:0090504 41 0.026
cellular response to dna damage stimulus GO:0006974 24 0.026
cell cell adhesion involved in mesendodermal cell migration GO:0003370 1 0.026
intrinsic apoptotic signaling pathway GO:0097193 20 0.026
cellular response to transforming growth factor beta stimulus GO:0071560 7 0.026
establishment of monopolar cell polarity GO:0061162 2 0.026
positive regulation of rna metabolic process GO:0051254 59 0.026
Human Mouse Worm Fly
negative regulation of growth GO:0045926 10 0.026
positive regulation of catalytic activity GO:0043085 25 0.025
Mouse Worm
negative regulation of cell communication GO:0010648 96 0.025
Zebrafish Mouse Fly
regulation of tube size GO:0035150 2 0.025
response to fluid shear stress GO:0034405 2 0.025
neural tube formation GO:0001841 16 0.025
negative regulation of rna metabolic process GO:0051253 48 0.025
Human Mouse
homeostatic process GO:0042592 142 0.025
Mouse
regulation of response to cytokine stimulus GO:0060759 3 0.025
convergent extension involved in gastrulation GO:0060027 71 0.025
ear development GO:0043583 127 0.025
macromolecular complex subunit organization GO:0043933 74 0.024
Worm
regulation of eye photoreceptor cell development GO:0042478 2 0.024
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.024
regulation of gastrulation GO:0010470 24 0.024
translational initiation GO:0006413 3 0.024
regulation of meiotic cell cycle GO:0051445 1 0.024
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.024
Mouse Fly
negative regulation of rna splicing GO:0033119 1 0.024
macromolecule deacylation GO:0098732 3 0.024
gtp catabolic process GO:0006184 2 0.024
mitotic cell cycle process GO:1903047 48 0.024
Worm
single organism cell adhesion GO:0098602 29 0.024
Human Mouse Worm Fly
macromolecule modification GO:0043412 111 0.024
Human Worm
optic placode formation involved in camera type eye formation GO:0046619 3 0.024
regulation of cell communication GO:0010646 232 0.024
Zebrafish Mouse Fly
phosphorus metabolic process GO:0006793 109 0.024
Mouse Worm
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.024
Human Mouse
sex determination GO:0007530 1 0.024
anterior head development GO:0097065 2 0.024
morphogenesis of embryonic epithelium GO:0016331 30 0.024
Mouse Fly
olfactory placode morphogenesis GO:0071699 7 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.023
Human Mouse
positive regulation of gene expression GO:0010628 71 0.023
Human Mouse Worm Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.023
neural tube patterning GO:0021532 33 0.023
lipid storage GO:0019915 1 0.023
determination of left right asymmetry in nervous system GO:0035545 4 0.023
positive regulation of signal transduction GO:0009967 56 0.023
Mouse
neural crest cell development GO:0014032 62 0.023
regulation of cell division GO:0051302 12 0.023
head development GO:0060322 303 0.023
Mouse
negative regulation of cellular catabolic process GO:0031330 3 0.022
response to drug GO:0042493 3 0.022
Human
neural crest cell migration GO:0001755 42 0.022
mesoderm morphogenesis GO:0048332 51 0.022
sequestering of calcium ion GO:0051208 3 0.022
biological adhesion GO:0022610 40 0.022
Human Mouse Worm Fly
death GO:0016265 121 0.022
Human Mouse Fly
axis elongation involved in somitogenesis GO:0090245 2 0.022
neural crest formation GO:0014029 14 0.022
regulation of translational initiation GO:0006446 1 0.022
microtubule based process GO:0007017 60 0.022
Human Worm
positive regulation of cellular component organization GO:0051130 13 0.022
Human
negative regulation of rna biosynthetic process GO:1902679 45 0.022
Human Mouse
cellular response to stress GO:0033554 62 0.022
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.021
mesenchymal cell differentiation GO:0048762 87 0.021
Human
rna localization GO:0006403 4 0.021
regulation of cellular component movement GO:0051270 55 0.021
Worm
phosphorylation GO:0016310 69 0.021
Mouse Worm
heart contraction GO:0060047 71 0.021
caudal fin development GO:0033336 9 0.021
determination of left right asymmetry in diencephalon GO:0035462 4 0.021
autophagy GO:0006914 4 0.021
response to transforming growth factor beta GO:0071559 7 0.021
pole plasm assembly GO:0007315 4 0.021
actin cytoskeleton organization GO:0030036 63 0.021
Worm
guanosine containing compound metabolic process GO:1901068 4 0.021
signal transduction by phosphorylation GO:0023014 18 0.020
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.020
Human Mouse Worm Fly
pigmentation GO:0043473 85 0.020
bone mineralization GO:0030282 9 0.020
spliceosomal complex assembly GO:0000245 1 0.020
cellular response to external stimulus GO:0071496 2 0.020
hindbrain development GO:0030902 91 0.020
tube closure GO:0060606 1 0.020
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.020
phosphate containing compound metabolic process GO:0006796 108 0.020
Mouse Worm
establishment of spindle localization GO:0051293 12 0.020
negative regulation of cell death GO:0060548 60 0.020
Human Mouse
sensory organ morphogenesis GO:0090596 200 0.019
Mouse Fly
circulatory system process GO:0003013 87 0.019
spindle localization GO:0051653 12 0.019
positive regulation of ras protein signal transduction GO:0046579 1 0.019
stem cell proliferation GO:0072089 4 0.019
Mouse
oxidation reduction process GO:0055114 41 0.019
heterocycle metabolic process GO:0046483 290 0.019
Human Mouse Worm Fly
apoptotic process GO:0006915 116 0.019
Human Mouse
positive regulation of epithelial cell proliferation GO:0050679 1 0.019
Mouse
regulation of erk1 and erk2 cascade GO:0070372 4 0.019
regulation of bone mineralization GO:0030500 2 0.019
negative regulation of mrna processing GO:0050686 1 0.019
cellular hormone metabolic process GO:0034754 19 0.019
divalent inorganic cation transport GO:0072511 21 0.019
Human
neural crest cell differentiation GO:0014033 72 0.019
post anal tail morphogenesis GO:0036342 19 0.019
defense response to fungus GO:0050832 2 0.019
regulation of developmental growth GO:0048638 38 0.019
negative regulation of sequestering of calcium ion GO:0051283 4 0.018
cytosolic calcium ion transport GO:0060401 3 0.018
positive regulation of histone deacetylation GO:0031065 1 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.018
Human Mouse Worm Fly
development of primary female sexual characteristics GO:0046545 4 0.018
meiotic cell cycle process GO:1903046 3 0.018
epithelium regeneration GO:1990399 14 0.018
bmp signaling pathway GO:0030509 52 0.018

ctnnb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
disease of cellular proliferation DOID:14566 0 0.024
Human
cancer DOID:162 0 0.021
Human
organ system cancer DOID:0050686 0 0.021
Human
nervous system disease DOID:863 0 0.021