Danio rerio

0 known processes

ctsl1a

cathepsin L, 1 a

(Aliases: ctsla,ik:tdsubc_2d2,wu:fb70e06,xx:tdsubc_2d2,hm:zeh1631,sb:cb143,ik:tdsubc_2f10,wu:fi15c08,xx:tdsubc_2f10)

ctsl1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to stress GO:0006950 263 0.594
Rat
aging GO:0007568 2 0.498
Rat
sensory organ development GO:0007423 393 0.476
negative regulation of cellular process GO:0048523 283 0.473
Mouse
death GO:0016265 121 0.434
Rat
signal transduction GO:0007165 455 0.372
response to abiotic stimulus GO:0009628 122 0.352
Zebrafish
response to external stimulus GO:0009605 264 0.316
Zebrafish Rat
response to organic substance GO:0010033 153 0.315
Human Rat
response to glucocorticoid GO:0051384 1 0.313
Rat
cell death GO:0008219 121 0.299
Rat
cell surface receptor signaling pathway GO:0007166 325 0.296
response to biotic stimulus GO:0009607 97 0.279
cellular response to external stimulus GO:0071496 2 0.261
Rat
lipid catabolic process GO:0016042 4 0.254
negative regulation of biological process GO:0048519 304 0.242
Mouse
gland development GO:0048732 143 0.237
regulation of response to oxidative stress GO:1902882 2 0.230
positive regulation of cellular process GO:0048522 201 0.225
response to oxygen containing compound GO:1901700 55 0.223
Rat
regulation of response to stimulus GO:0048583 269 0.220
regulation of signaling GO:0023051 235 0.219
cellular macromolecule metabolic process GO:0044260 391 0.212
Human
regulation of multicellular organismal process GO:0051239 277 0.204
defense response to other organism GO:0098542 33 0.203
negative regulation of response to stimulus GO:0048585 104 0.202
embryonic organ development GO:0048568 381 0.192
cellular response to stress GO:0033554 62 0.190
Rat
cellular response to starvation GO:0009267 1 0.182
Rat
tube morphogenesis GO:0035239 349 0.177
camera type eye development GO:0043010 222 0.176
immune system process GO:0002376 241 0.175
Human
morphogenesis of an epithelium GO:0002009 333 0.174
Mouse
response to monosaccharide GO:0034284 3 0.172
Rat
response to bacterium GO:0009617 58 0.165
g protein coupled receptor signaling pathway GO:0007186 74 0.165
cellular response to nutrient levels GO:0031669 2 0.165
Rat
response to other organism GO:0051707 97 0.160
response to external biotic stimulus GO:0043207 97 0.158
defense response GO:0006952 47 0.157
establishment of protein localization to organelle GO:0072594 4 0.149
response to mechanical stimulus GO:0009612 24 0.148
Zebrafish
developmental growth GO:0048589 166 0.147
regulation of cellular response to oxidative stress GO:1900407 2 0.140
larval development GO:0002164 2 0.136
response to chemical GO:0042221 320 0.135
Human Rat
biosynthetic process GO:0009058 294 0.135
negative regulation of cell death GO:0060548 60 0.134
eye development GO:0001654 277 0.132
regulation of primary metabolic process GO:0080090 311 0.131
cellular protein catabolic process GO:0044257 4 0.123
Human
response to lipid GO:0033993 60 0.123
Rat
response to corticosteroid GO:0031960 1 0.121
Rat
response to organic cyclic compound GO:0014070 51 0.120
Rat
regulation of cell communication GO:0010646 232 0.119
protein metabolic process GO:0019538 183 0.119
Human Mouse Rat
defense response to bacterium GO:0042742 22 0.115
multicellular organismal metabolic process GO:0044236 2 0.115
Human
cell death in response to oxidative stress GO:0036473 2 0.112
autophagy GO:0006914 4 0.111
regulation of nitrogen compound metabolic process GO:0051171 251 0.110
response to hexose GO:0009746 3 0.107
Rat
positive regulation of inflammatory response GO:0050729 1 0.104
single organism metabolic process GO:0044710 217 0.103
Human
regulation of epithelial cell proliferation GO:0050678 3 0.103
Mouse
regulation of multicellular organism growth GO:0040014 4 0.102
regeneration GO:0031099 91 0.100
regulation of response to stress GO:0080134 36 0.097
response to antibiotic GO:0046677 1 0.097
positive regulation of transport GO:0051050 2 0.097
multicellular organism growth GO:0035264 4 0.096
regulation of cell death GO:0010941 103 0.096
locomotion GO:0040011 313 0.094
regulation of apoptotic process GO:0042981 98 0.089
vasculature development GO:0001944 278 0.088
hepaticobiliary system development GO:0061008 98 0.086
carboxylic acid metabolic process GO:0019752 22 0.085
response to drug GO:0042493 3 0.085
single organism transport GO:0044765 206 0.084
regulation of oxidative stress induced cell death GO:1903201 2 0.084
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.083
positive regulation of biological process GO:0048518 253 0.083
protein targeting to nucleus GO:0044744 3 0.082
regulation of inflammatory response GO:0050727 2 0.082
anion transport GO:0006820 38 0.081
protein localization to nucleus GO:0034504 3 0.080
collagen metabolic process GO:0032963 2 0.079
Human
cellular response to extracellular stimulus GO:0031668 2 0.078
Rat
single organism localization GO:1902578 225 0.077
neurological system process GO:0050877 62 0.074
regulation of signal transduction GO:0009966 225 0.073
response to inorganic substance GO:0010035 38 0.073
apoptotic process GO:0006915 116 0.072
regulation of reactive oxygen species metabolic process GO:2000377 2 0.072
dicarboxylic acid transport GO:0006835 1 0.071
multi organism process GO:0051704 134 0.070
Mouse Rat
regulation of cytoplasmic transport GO:1903649 4 0.070
regulation of macromolecule metabolic process GO:0060255 317 0.070
cellular response to organic substance GO:0071310 105 0.069
Human
determination of bilateral symmetry GO:0009855 204 0.069
regulation of developmental process GO:0050793 247 0.068
positive regulation of secretion by cell GO:1903532 1 0.068
transport GO:0006810 220 0.067
cognition GO:0050890 1 0.066
extrinsic apoptotic signaling pathway GO:0097191 3 0.065
nuclear import GO:0051170 3 0.065
response to amino acid GO:0043200 2 0.065
cellular response to lipopolysaccharide GO:0071222 3 0.064
negative regulation of cell communication GO:0010648 96 0.064
maintenance of location GO:0051235 4 0.063
single organism reproductive process GO:0044702 40 0.062
Mouse Rat
regulation of cellular metabolic process GO:0031323 320 0.061
cellular response to chemical stimulus GO:0070887 157 0.061
Human
regulation of system process GO:0044057 40 0.060
cellular component movement GO:0006928 335 0.060
developmental programmed cell death GO:0010623 4 0.059
regulation of establishment of protein localization GO:0070201 4 0.059
response to alkaloid GO:0043279 2 0.059
regulation of protein import into nucleus GO:0042306 2 0.058
hematopoietic or lymphoid organ development GO:0048534 191 0.058
growth GO:0040007 174 0.057
reactive nitrogen species metabolic process GO:2001057 0 0.057
apoptotic process involved in development GO:1902742 2 0.056
regulation of metal ion transport GO:0010959 4 0.056
sensory organ morphogenesis GO:0090596 200 0.056
lipid storage GO:0019915 1 0.056
hormone transport GO:0009914 2 0.055
negative regulation of defense response GO:0031348 2 0.055
positive regulation of cell cycle GO:0045787 3 0.055
multicellular organismal macromolecule metabolic process GO:0044259 2 0.055
Human
response to hydrogen peroxide GO:0042542 3 0.054
nucleocytoplasmic transport GO:0006913 4 0.054
regulation of gene expression GO:0010468 265 0.054
cellular response to endogenous stimulus GO:0071495 68 0.054
Human
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.052
positive regulation of secretion GO:0051047 1 0.052
response to oxygen levels GO:0070482 25 0.052
single organism nuclear import GO:1902593 3 0.052
glucose homeostasis GO:0042593 1 0.051
regulation of cytokine production GO:0001817 3 0.051
regulation of protein transport GO:0051223 3 0.051
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.051
regulation of hormone secretion GO:0046883 2 0.050
defense response to gram negative bacterium GO:0050829 8 0.050
regulation of programmed cell death GO:0043067 101 0.049
wound healing GO:0042060 90 0.048
blood vessel development GO:0001568 246 0.048
appendage development GO:0048736 80 0.048
cellular response to molecule of bacterial origin GO:0071219 3 0.048
regulation of defense response GO:0031347 14 0.048
gastrulation GO:0007369 208 0.047
nuclear transport GO:0051169 4 0.047
developmental process involved in reproduction GO:0003006 27 0.047
Mouse Rat
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.047
Human
regulation of production of molecular mediator of immune response GO:0002700 1 0.046
regulation of dendrite development GO:0050773 3 0.046
cell migration GO:0016477 237 0.046
negative regulation of signaling GO:0023057 96 0.045
system process GO:0003008 185 0.044
regulation of nucleocytoplasmic transport GO:0046822 2 0.044
organic substance biosynthetic process GO:1901576 289 0.044
regulation of protein catabolic process GO:0042176 1 0.044
cellular biosynthetic process GO:0044249 286 0.044
negative regulation of apoptotic process GO:0043066 55 0.043
negative regulation of cytokine production GO:0001818 1 0.043
establishment of rna localization GO:0051236 3 0.043
localization of cell GO:0051674 244 0.042
ion transport GO:0006811 114 0.042
programmed cell death GO:0012501 119 0.042
Rat
regulation of membrane potential GO:0042391 23 0.042
fatty acid transport GO:0015908 1 0.041
urogenital system development GO:0001655 97 0.041
negative regulation of secretion GO:0051048 2 0.041
regionalization GO:0003002 274 0.040
oxoacid metabolic process GO:0043436 31 0.040
nitric oxide biosynthetic process GO:0006809 2 0.040
establishment of localization GO:0051234 244 0.040
adult behavior GO:0030534 2 0.040
response to ketone GO:1901654 1 0.040
response to decreased oxygen levels GO:0036293 25 0.040
immune system development GO:0002520 191 0.039
regulation of metabolic process GO:0019222 359 0.039
production of molecular mediator of immune response GO:0002440 2 0.039
regulation of cellular response to stress GO:0080135 20 0.039
reactive oxygen species biosynthetic process GO:1903409 1 0.039
regulation of intracellular protein transport GO:0033157 3 0.039
proteolysis GO:0006508 38 0.038
Human Mouse Rat
cellular ketone metabolic process GO:0042180 11 0.038
positive regulation of cytokine production GO:0001819 2 0.038
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.038
organic cyclic compound metabolic process GO:1901360 301 0.038
regulation of biological quality GO:0065008 263 0.037
peptide transport GO:0015833 1 0.037
organic cyclic compound biosynthetic process GO:1901362 223 0.036
cellular response to reactive oxygen species GO:0034614 2 0.036
response to wounding GO:0009611 116 0.036
macromolecule biosynthetic process GO:0009059 227 0.036
response to nutrient GO:0007584 3 0.036
embryo development ending in birth or egg hatching GO:0009792 271 0.035
regulation of protein targeting GO:1903533 2 0.035
synaptic growth at neuromuscular junction GO:0051124 2 0.035
stem cell proliferation GO:0072089 4 0.035
negative regulation of nuclear division GO:0051784 3 0.035
positive regulation of apoptotic signaling pathway GO:2001235 1 0.034
multicellular organismal homeostasis GO:0048871 29 0.034
small molecule catabolic process GO:0044282 3 0.034
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.034
cell motility GO:0048870 244 0.034
embryonic limb morphogenesis GO:0030326 2 0.034
regulation of organ growth GO:0046620 3 0.034
nitrogen compound metabolic process GO:0006807 319 0.034
response to copper ion GO:0046688 13 0.033
response to amine GO:0014075 1 0.033
regulation of synapse organization GO:0050807 3 0.033
amide transport GO:0042886 12 0.032
nucleic acid transport GO:0050657 2 0.032
positive regulation of catabolic process GO:0009896 4 0.032
regulation of protein complex assembly GO:0043254 3 0.032
liver development GO:0001889 96 0.032
response to reactive oxygen species GO:0000302 5 0.031
immune response GO:0006955 28 0.031
Human
nitrogen compound transport GO:0071705 23 0.031
cellular aromatic compound metabolic process GO:0006725 295 0.031
gene expression GO:0010467 252 0.031
Mouse
response to transition metal nanoparticle GO:1990267 28 0.031
organic acid metabolic process GO:0006082 31 0.031
long chain fatty acid transport GO:0015909 1 0.031
modification dependent protein catabolic process GO:0019941 3 0.030
regulation of cell activation GO:0050865 1 0.030
digestive tract morphogenesis GO:0048546 231 0.030
regulation of muscle hypertrophy GO:0014743 2 0.030
signal transduction in absence of ligand GO:0038034 1 0.030
cellular response to oxygen levels GO:0071453 1 0.030
organonitrogen compound metabolic process GO:1901564 74 0.030
embryonic cranial skeleton morphogenesis GO:0048701 90 0.029
response to glucose GO:0009749 3 0.029
Rat
mitochondrial transport GO:0006839 2 0.029
regulation of immune system process GO:0002682 34 0.029
cellular nitrogen compound biosynthetic process GO:0044271 218 0.029
homeostatic process GO:0042592 142 0.029
transcription from rna polymerase ii promoter GO:0006366 80 0.029
positive regulation of cellular component biogenesis GO:0044089 3 0.029
epithelial cell differentiation GO:0030855 116 0.029
Rat
regulation of blood vessel size GO:0050880 2 0.029
protein import into nucleus GO:0006606 3 0.028
protein import GO:0017038 3 0.028
ameboidal type cell migration GO:0001667 143 0.028
morphogenesis of an epithelial fold GO:0060571 1 0.028
retina development in camera type eye GO:0060041 146 0.028
negative regulation of protein complex assembly GO:0031333 1 0.028
regulation of cellular amine metabolic process GO:0033238 0 0.028
internal peptidyl lysine acetylation GO:0018393 2 0.028
positive regulation of cellular metabolic process GO:0031325 94 0.028
cellular extravasation GO:0045123 1 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.027
cellular nitrogen compound metabolic process GO:0034641 290 0.027
regulation of cellular protein catabolic process GO:1903362 1 0.027
regulation of neurogenesis GO:0050767 87 0.027
alcohol biosynthetic process GO:0046165 2 0.027
tissue regeneration GO:0042246 74 0.027
hormone secretion GO:0046879 2 0.027
regulation of cellular biosynthetic process GO:0031326 245 0.027
organic substance transport GO:0071702 58 0.027
positive regulation of multicellular organismal process GO:0051240 52 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
neuroblast proliferation GO:0007405 2 0.027
mitochondrion organization GO:0007005 4 0.027
generation of neurons GO:0048699 385 0.027
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.026
response to carbohydrate GO:0009743 3 0.026
Rat
cellular amine metabolic process GO:0044106 2 0.026
positive regulation of neuron death GO:1901216 1 0.026
negative regulation of signal transduction GO:0009968 94 0.026
positive regulation of cellular amine metabolic process GO:0033240 0 0.026
cellular macromolecule biosynthetic process GO:0034645 224 0.026
regulation of phosphate metabolic process GO:0019220 43 0.026
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.026
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 5 0.026
amine metabolic process GO:0009308 2 0.026
protein stabilization GO:0050821 2 0.026
cellular response to biotic stimulus GO:0071216 3 0.026
enzyme linked receptor protein signaling pathway GO:0007167 106 0.026
regulation of anatomical structure morphogenesis GO:0022603 130 0.026
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.025
cell proliferation GO:0008283 80 0.025
Mouse
organic substance catabolic process GO:1901575 28 0.025
Human
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
positive regulation of metabolic process GO:0009893 108 0.025
response to nutrient levels GO:0031667 10 0.025
Rat
negative regulation of kinase activity GO:0033673 4 0.025
regulation of cellular component organization GO:0051128 86 0.024
Mouse
digestive tract development GO:0048565 265 0.024
regulation of dna replication GO:0006275 3 0.024
lateral line system development GO:0048925 76 0.024
nucleic acid metabolic process GO:0090304 244 0.024
gamete generation GO:0007276 33 0.024
Rat
secondary metabolic process GO:0019748 3 0.023
regulation of hormone levels GO:0010817 21 0.023
transcription dna templated GO:0006351 181 0.023
response to starvation GO:0042594 5 0.023
Rat
cellular response to oxidative stress GO:0034599 5 0.023
membrane invagination GO:0010324 1 0.023
response to extracellular stimulus GO:0009991 10 0.023
Rat
muscle hypertrophy GO:0014896 2 0.023
hemopoiesis GO:0030097 183 0.023
zymogen activation GO:0031638 3 0.023
positive regulation of protein complex assembly GO:0031334 2 0.023
response to lipopolysaccharide GO:0032496 13 0.023
sensory system development GO:0048880 76 0.023
aromatic compound biosynthetic process GO:0019438 217 0.023
cellular protein metabolic process GO:0044267 129 0.023
Human
regulation of chronic inflammatory response GO:0002676 1 0.022
response to nitrogen compound GO:1901698 19 0.022
regulation of phosphorus metabolic process GO:0051174 43 0.022
catabolic process GO:0009056 32 0.022
Human
sulfur compound metabolic process GO:0006790 13 0.022
regulation of multicellular organismal development GO:2000026 223 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
regulation of biosynthetic process GO:0009889 250 0.022
cell projection morphogenesis GO:0048858 244 0.022
negative regulation of programmed cell death GO:0043069 58 0.022
tissue remodeling GO:0048771 4 0.022
protein homooligomerization GO:0051260 3 0.022
positive regulation of developmental process GO:0051094 50 0.022
cellular aldehyde metabolic process GO:0006081 4 0.022
nitric oxide metabolic process GO:0046209 2 0.022
negative regulation of secretion by cell GO:1903531 2 0.021
single organism intracellular transport GO:1902582 25 0.021
metal ion transport GO:0030001 58 0.021
stem cell division GO:0017145 1 0.021
regulation of nervous system development GO:0051960 90 0.021
positive regulation of jnk cascade GO:0046330 3 0.021
skeletal system development GO:0001501 181 0.021
negative regulation of hormone secretion GO:0046888 2 0.021
rna metabolic process GO:0016070 219 0.021
heart development GO:0007507 313 0.021
cell migration involved in gastrulation GO:0042074 79 0.021
respiratory system development GO:0060541 5 0.021
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
positive regulation of neuron apoptotic process GO:0043525 1 0.021
nuclear export GO:0051168 1 0.021
single organism biosynthetic process GO:0044711 71 0.021
regulation of tube size GO:0035150 2 0.021
cellular response to oxygen containing compound GO:1901701 20 0.021
positive regulation of response to wounding GO:1903036 5 0.021
response to oxidative stress GO:0006979 11 0.021
epithelial tube morphogenesis GO:0060562 148 0.020
cellular component biogenesis GO:0044085 178 0.020
mitotic nuclear division GO:0007067 18 0.020
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.020
carbohydrate homeostasis GO:0033500 1 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
regulation of protein localization to nucleus GO:1900180 2 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
protein acylation GO:0043543 3 0.020
neuron development GO:0048666 262 0.020
ubiquitin dependent protein catabolic process GO:0006511 3 0.020
cell projection organization GO:0030030 284 0.020
negative regulation of mitosis GO:0045839 3 0.020
positive regulation of cell activation GO:0050867 1 0.020
positive regulation of epithelial cell proliferation GO:0050679 1 0.020
p38mapk cascade GO:0038066 1 0.020
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.020
ear development GO:0043583 127 0.020
carboxylic acid transport GO:0046942 8 0.020
cellular component assembly GO:0022607 170 0.020
regulation of binding GO:0051098 3 0.019
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 5 0.019
regulation of localization GO:0032879 104 0.019
long chain fatty acid metabolic process GO:0001676 1 0.019
i kappab kinase nf kappab signaling GO:0007249 4 0.019
regulation of response to external stimulus GO:0032101 31 0.019
positive regulation of immune effector process GO:0002699 3 0.019
regulation of wound healing GO:0061041 2 0.019
regulation of blood pressure GO:0008217 1 0.019
phosphate containing compound metabolic process GO:0006796 108 0.019
angiogenesis GO:0001525 158 0.019
intracellular signal transduction GO:0035556 85 0.019
reactive oxygen species metabolic process GO:0072593 6 0.019
amino acid transport GO:0006865 2 0.019
determination of left right symmetry GO:0007368 179 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
embryonic organ morphogenesis GO:0048562 274 0.019
b cell activation GO:0042113 2 0.019
organ regeneration GO:0031100 1 0.019
ion transmembrane transport GO:0034220 91 0.019
cellular response to hormone stimulus GO:0032870 39 0.019
Human
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.018
regulation of heart growth GO:0060420 2 0.018
protein localization GO:0008104 40 0.018
organic anion transport GO:0015711 15 0.018
regulation of growth GO:0040008 42 0.018
rna localization GO:0006403 4 0.018
lymphocyte proliferation GO:0046651 1 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
regulation of translational initiation GO:0006446 1 0.018
neurotransmitter secretion GO:0007269 2 0.018
posterior lateral line system development GO:0048915 46 0.018
appendage morphogenesis GO:0035107 56 0.018
fin regeneration GO:0031101 51 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.018
post embryonic organ development GO:0048569 4 0.018
cytokine metabolic process GO:0042107 1 0.018
regulation of rna biosynthetic process GO:2001141 213 0.018
small molecule metabolic process GO:0044281 77 0.017
negative regulation of catabolic process GO:0009895 3 0.017
regulation of calcium ion transport GO:0051924 2 0.017
metal ion homeostasis GO:0055065 26 0.017
ph reduction GO:0045851 1 0.017
macromolecule catabolic process GO:0009057 15 0.017
Human
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.017
cofactor metabolic process GO:0051186 15 0.017
response to arsenic containing substance GO:0046685 5 0.017
response to acidic ph GO:0010447 2 0.017
stem cell maintenance GO:0019827 4 0.017
chordate embryonic development GO:0043009 271 0.017
dorsal ventral pattern formation GO:0009953 125 0.017
tissue homeostasis GO:0001894 25 0.017
neuromuscular synaptic transmission GO:0007274 2 0.017
digestive system development GO:0055123 289 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.017
glial cell migration GO:0008347 3 0.017
response to endogenous stimulus GO:0009719 83 0.017
Human Rat
establishment of localization in cell GO:0051649 77 0.016
negative regulation of multicellular organismal process GO:0051241 69 0.016
somitogenesis GO:0001756 87 0.016
positive regulation of signal transduction GO:0009967 56 0.016
regulation of organelle organization GO:0033043 29 0.016
Mouse
cellular response to decreased oxygen levels GO:0036294 1 0.016
neuron projection regeneration GO:0031102 16 0.016
negative regulation of epithelial cell proliferation GO:0050680 1 0.016
Mouse
guanosine containing compound metabolic process GO:1901068 4 0.016
cellular localization GO:0051641 97 0.016
retina morphogenesis in camera type eye GO:0060042 79 0.016
response to steroid hormone GO:0048545 35 0.016
Rat
mechanosensory lateral line system development GO:0048881 49 0.016
blood circulation GO:0008015 87 0.016
mitotic dna integrity checkpoint GO:0044774 4 0.016
innate immune response GO:0045087 13 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
sensory perception of mechanical stimulus GO:0050954 16 0.015
negative regulation of cellular component organization GO:0051129 16 0.015
diterpenoid metabolic process GO:0016101 15 0.015
positive regulation of response to stimulus GO:0048584 80 0.015
regulation of intracellular signal transduction GO:1902531 57 0.015
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.015
macromolecular complex subunit organization GO:0043933 74 0.015
regulation of p38mapk cascade GO:1900744 1 0.015
cellular protein modification process GO:0006464 100 0.015
membrane lipid biosynthetic process GO:0046467 2 0.015
response to oxygen radical GO:0000305 2 0.015
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.015
positive regulation of dna metabolic process GO:0051054 1 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
cellular response to unfolded protein GO:0034620 2 0.015
response to hormone GO:0009725 48 0.015
Human Rat
reproductive process GO:0022414 40 0.015
Mouse Rat
positive regulation of cell communication GO:0010647 56 0.015
transmission of nerve impulse GO:0019226 19 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
protein complex localization GO:0031503 1 0.015
chemical homeostasis GO:0048878 49 0.015
homeostasis of number of cells within a tissue GO:0048873 4 0.015
negative regulation of dna replication GO:0008156 2 0.015
rna transport GO:0050658 2 0.015
cellular component disassembly GO:0022411 1 0.015
lipid metabolic process GO:0006629 52 0.015
circulatory system process GO:0003013 87 0.015
regulation of synapse assembly GO:0051963 3 0.015
regulation of transcription dna templated GO:0006355 213 0.015
positive regulation of stress activated mapk cascade GO:0032874 3 0.014
regulation of protein metabolic process GO:0051246 56 0.014
regulation of postsynaptic membrane potential GO:0060078 1 0.014
endocrine system development GO:0035270 65 0.014
specification of symmetry GO:0009799 204 0.014
inner ear development GO:0048839 126 0.014
regulation of neuron differentiation GO:0045664 56 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
fat soluble vitamin metabolic process GO:0006775 4 0.014
protein localization to plasma membrane GO:0072659 1 0.014

ctsl1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.731
lysosomal storage disease DOID:3211 0 0.731
inherited metabolic disorder DOID:655 0 0.731
disease of anatomical entity DOID:7 0 0.094
nervous system disease DOID:863 0 0.055
cancer DOID:162 0 0.050
disease of cellular proliferation DOID:14566 0 0.050
organ system cancer DOID:0050686 0 0.050
immune system disease DOID:2914 0 0.022
central nervous system disease DOID:331 0 0.018
brain disease DOID:936 0 0.018
large intestine cancer DOID:5672 0 0.017
gastrointestinal system cancer DOID:3119 0 0.017
intestinal cancer DOID:10155 0 0.017
colon carcinoma DOID:1520 0 0.014
colon cancer DOID:219 0 0.014
colorectal cancer DOID:9256 0 0.014