Danio rerio

24 known processes

cx35

connexin 35

(Aliases: gja9,connexin35)

cx35 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of circadian sleep wake cycle GO:0042749 1 0.513
ion transport GO:0006811 114 0.319
sensory organ development GO:0007423 393 0.231
Zebrafish
signal transduction GO:0007165 455 0.199
response to stress GO:0006950 263 0.195
Zebrafish
regulation of biological quality GO:0065008 263 0.159
Mouse
absorption of visible light GO:0016038 2 0.142
aging GO:0007568 2 0.136
circadian sleep wake cycle sleep GO:0050802 1 0.134
response to chemical GO:0042221 320 0.126
establishment of localization GO:0051234 244 0.116
protein metabolic process GO:0019538 183 0.111
circadian sleep wake cycle process GO:0022410 2 0.111
response to organic substance GO:0010033 153 0.100
regulation of sequestering of calcium ion GO:0051282 4 0.097
regulation of primary metabolic process GO:0080090 311 0.094
circadian sleep wake cycle GO:0042745 2 0.094
cell surface receptor signaling pathway GO:0007166 325 0.094
sleep GO:0030431 1 0.092
angiogenesis GO:0001525 158 0.087
heart development GO:0007507 313 0.086
Zebrafish
maintenance of location GO:0051235 4 0.085
positive regulation of transport GO:0051050 2 0.081
oxoacid metabolic process GO:0043436 31 0.076
myofibril assembly GO:0030239 48 0.076
Zebrafish
biosynthetic process GO:0009058 294 0.076
photoperiodism GO:0009648 11 0.075
carboxylic acid metabolic process GO:0019752 22 0.073
nitrogen compound metabolic process GO:0006807 319 0.071
tissue regeneration GO:0042246 74 0.070
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.067
single organism transport GO:0044765 206 0.066
small molecule metabolic process GO:0044281 77 0.066
cellular response to organic substance GO:0071310 105 0.065
negative regulation of cellular process GO:0048523 283 0.065
organonitrogen compound metabolic process GO:1901564 74 0.064
organic acid metabolic process GO:0006082 31 0.063
cellular component assembly involved in morphogenesis GO:0010927 107 0.062
Zebrafish
transport GO:0006810 220 0.061
digestive tract development GO:0048565 265 0.061
positive regulation of cellular process GO:0048522 201 0.059
response to estrogen GO:0043627 27 0.059
organic substance biosynthetic process GO:1901576 289 0.057
inorganic ion transmembrane transport GO:0098660 57 0.057
blood vessel morphogenesis GO:0048514 216 0.056
regulation of multicellular organismal development GO:2000026 223 0.056
single organism metabolic process GO:0044710 217 0.056
posterior lateral line development GO:0048916 38 0.056
inorganic anion transport GO:0015698 25 0.056
regulation of biosynthetic process GO:0009889 250 0.054
g protein coupled receptor signaling pathway GO:0007186 74 0.053
regulation of inflammatory response GO:0050727 2 0.053
cellular amino acid metabolic process GO:0006520 7 0.052
regulation of metal ion transport GO:0010959 4 0.051
organic cyclic compound metabolic process GO:1901360 301 0.051
regulation of transmembrane transport GO:0034762 18 0.049
adrenergic receptor signaling pathway GO:0071875 5 0.046
immune system development GO:0002520 191 0.046
Zebrafish
cell death GO:0008219 121 0.046
liver development GO:0001889 96 0.045
cellular response to chemical stimulus GO:0070887 157 0.045
neuron development GO:0048666 262 0.045
death GO:0016265 121 0.045
amine metabolic process GO:0009308 2 0.044
transmembrane transport GO:0055085 120 0.044
pigmentation GO:0043473 85 0.041
Zebrafish
system process GO:0003008 185 0.041
Zebrafish Mouse
eye development GO:0001654 277 0.040
apoptotic process GO:0006915 116 0.040
response to external stimulus GO:0009605 264 0.040
larval development GO:0002164 2 0.038
single organism localization GO:1902578 225 0.038
cellular macromolecule biosynthetic process GO:0034645 224 0.037
digestive system development GO:0055123 289 0.037
anion transport GO:0006820 38 0.036
regulation of signaling GO:0023051 235 0.035
intracellular signal transduction GO:0035556 85 0.035
camera type eye development GO:0043010 222 0.035
regulation of hormone secretion GO:0046883 2 0.035
nucleobase containing compound metabolic process GO:0006139 274 0.034
organelle organization GO:0006996 227 0.034
Zebrafish
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.034
regulation of cellular metabolic process GO:0031323 320 0.033
sensory perception of chemical stimulus GO:0007606 3 0.033
organelle assembly GO:0070925 110 0.032
Zebrafish
regulation of cell differentiation GO:0045595 142 0.032
ion transmembrane transport GO:0034220 91 0.032
regulation of transport GO:0051049 45 0.032
cellular response to hormone stimulus GO:0032870 39 0.032
cellular aromatic compound metabolic process GO:0006725 295 0.031
multicellular organism growth GO:0035264 4 0.031
cellular macromolecule metabolic process GO:0044260 391 0.031
gastrulation GO:0007369 208 0.031
regulation of cell development GO:0060284 100 0.031
alpha amino acid metabolic process GO:1901605 3 0.030
regulation of metabolic process GO:0019222 359 0.030
regulation of growth rate GO:0040009 1 0.030
regulation of ion transmembrane transport GO:0034765 18 0.030
cellular amine metabolic process GO:0044106 2 0.030
negative regulation of sequestering of calcium ion GO:0051283 4 0.029
negative regulation of camp metabolic process GO:0030815 7 0.029
cellular response to radiation GO:0071478 4 0.029
cation transmembrane transport GO:0098655 65 0.029
regulation of rna biosynthetic process GO:2001141 213 0.028
cellular response to light stimulus GO:0071482 4 0.028
regulation of developmental process GO:0050793 247 0.028
macromolecule biosynthetic process GO:0009059 227 0.028
response to endogenous stimulus GO:0009719 83 0.028
immune system process GO:0002376 241 0.028
Zebrafish
apical junction assembly GO:0043297 1 0.027
cellular biosynthetic process GO:0044249 286 0.027
regulation of cellular ketone metabolic process GO:0010565 7 0.026
response to nutrient GO:0007584 3 0.026
inorganic cation transmembrane transport GO:0098662 50 0.026
regulation of gene expression GO:0010468 265 0.026
heterocycle metabolic process GO:0046483 290 0.026
multi organism process GO:0051704 134 0.026
blood circulation GO:0008015 87 0.026
sensory organ morphogenesis GO:0090596 200 0.026
single organism behavior GO:0044708 24 0.026
muscle system process GO:0003012 20 0.025
positive regulation of catabolic process GO:0009896 4 0.025
vasculature development GO:0001944 278 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.024
hemopoiesis GO:0030097 183 0.024
Zebrafish
regulation of cell death GO:0010941 103 0.024
cytokinesis GO:0000910 3 0.024
carboxylic acid catabolic process GO:0046395 3 0.024
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
neurotransmitter transport GO:0006836 2 0.024
regulation of establishment of protein localization GO:0070201 4 0.024
gene expression GO:0010467 252 0.023
muscle contraction GO:0006936 18 0.023
protein modification process GO:0036211 100 0.023
regulation of localization GO:0032879 104 0.023
cell cycle GO:0007049 93 0.023
cellular nitrogen compound metabolic process GO:0034641 290 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
embryonic organ morphogenesis GO:0048562 274 0.022
Zebrafish
regulation of response to stimulus GO:0048583 269 0.022
regulation of cell communication GO:0010646 232 0.022
circadian regulation of gene expression GO:0032922 8 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.022
enzyme linked receptor protein signaling pathway GO:0007167 106 0.021
cell cycle g1 s phase transition GO:0044843 1 0.021
response to abiotic stimulus GO:0009628 122 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
regulation of innate immune response GO:0045088 11 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
reflex GO:0060004 2 0.020
sequestering of calcium ion GO:0051208 3 0.020
response to hormone GO:0009725 48 0.020
regulation of macromolecule metabolic process GO:0060255 317 0.020
ameboidal type cell migration GO:0001667 143 0.020
mesenchymal cell differentiation GO:0048762 87 0.020
transmission of nerve impulse GO:0019226 19 0.019
establishment of vesicle localization GO:0051650 24 0.019
negative regulation of signaling GO:0023057 96 0.019
morphogenesis of an epithelium GO:0002009 333 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
regulation of reproductive process GO:2000241 4 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
digestive tract morphogenesis GO:0048546 231 0.019
negative regulation of camp biosynthetic process GO:0030818 7 0.019
startle response GO:0001964 4 0.019
response to osmotic stress GO:0006970 11 0.019
entrainment of circadian clock by photoperiod GO:0043153 1 0.018
cellular aldehyde metabolic process GO:0006081 4 0.018
response to wounding GO:0009611 116 0.018
Zebrafish
small molecule catabolic process GO:0044282 3 0.018
response to nicotine GO:0035094 2 0.018
response to organic cyclic compound GO:0014070 51 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
cell morphogenesis GO:0000902 289 0.018
regulation of cell cycle GO:0051726 52 0.017
actin cytoskeleton organization GO:0030036 63 0.017
Zebrafish
regulation of blood pressure GO:0008217 1 0.017
mechanosensory lateral line system development GO:0048881 49 0.017
rhodopsin mediated signaling pathway GO:0016056 1 0.017
stem cell differentiation GO:0048863 117 0.017
mesenchyme development GO:0060485 127 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.017
mitochondrion organization GO:0007005 4 0.017
programmed cell death GO:0012501 119 0.016
cation transport GO:0006812 81 0.016
establishment of localization in cell GO:0051649 77 0.016
hormone transport GO:0009914 2 0.016
hepaticobiliary system development GO:0061008 98 0.016
positive regulation of biological process GO:0048518 253 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
regulation of protein transport GO:0051223 3 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.016
lateral line system development GO:0048925 76 0.016
cell projection organization GO:0030030 284 0.016
developmental growth GO:0048589 166 0.015
Zebrafish
inositol lipid mediated signaling GO:0048017 2 0.015
response to ketone GO:1901654 1 0.015
regulation of systemic arterial blood pressure GO:0003073 1 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
response to light stimulus GO:0009416 46 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
locomotor rhythm GO:0045475 3 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.015
Zebrafish
regulation of cell activation GO:0050865 1 0.015
circadian rhythm GO:0007623 19 0.014
anion transmembrane transport GO:0098656 12 0.014
er nucleus signaling pathway GO:0006984 2 0.014
circulatory system process GO:0003013 87 0.014
response to unfolded protein GO:0006986 2 0.014
smooth muscle contraction GO:0006939 2 0.014
negative regulation of signal transduction GO:0009968 94 0.014
rna biosynthetic process GO:0032774 181 0.014
cellular component movement GO:0006928 335 0.014
epiboly GO:0090504 41 0.014
negative regulation of developmental process GO:0051093 65 0.014
lateral line development GO:0048882 66 0.014
muscle organ development GO:0007517 101 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
organic acid catabolic process GO:0016054 3 0.013
striated muscle tissue development GO:0014706 110 0.013
Zebrafish
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
cellular protein metabolic process GO:0044267 129 0.013
regulation of circadian rhythm GO:0042752 4 0.013
peptide transport GO:0015833 1 0.013
exocytosis GO:0006887 1 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
peristalsis GO:0030432 1 0.013
hormone secretion GO:0046879 2 0.013
muscle cell differentiation GO:0042692 139 0.013
Zebrafish
negative regulation of rna metabolic process GO:0051253 48 0.013
negative regulation of programmed cell death GO:0043069 58 0.013
negative regulation of biosynthetic process GO:0009890 55 0.013
regulation of rna metabolic process GO:0051252 224 0.013
regulation of neurogenesis GO:0050767 87 0.013
negative regulation of cell death GO:0060548 60 0.013
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.012
fin regeneration GO:0031101 51 0.012
Zebrafish
action potential GO:0001508 19 0.012
Mouse
positive regulation of leukocyte mediated immunity GO:0002705 1 0.012
muscle structure development GO:0061061 196 0.012
Zebrafish
positive regulation of secretion GO:0051047 1 0.012
cell motility GO:0048870 244 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
calcium ion homeostasis GO:0055074 19 0.012
embryonic skeletal joint morphogenesis GO:0060272 3 0.012
Zebrafish
posterior lateral line nerve glial cell development GO:0048941 5 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
entrainment of circadian clock GO:0009649 2 0.012
eye morphogenesis GO:0048592 144 0.012
embryonic organ development GO:0048568 381 0.012
Zebrafish
cell proliferation GO:0008283 80 0.012
Zebrafish
heart process GO:0003015 71 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
response to radiation GO:0009314 51 0.012
sensory system development GO:0048880 76 0.011
negative regulation of lyase activity GO:0051350 6 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.011
nuclear transport GO:0051169 4 0.011
positive regulation of striated muscle tissue development GO:0045844 1 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.011
post embryonic organ development GO:0048569 4 0.011
rna metabolic process GO:0016070 219 0.011
cell part morphogenesis GO:0032990 246 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
neural crest cell differentiation GO:0014033 72 0.011
negative regulation of defense response GO:0031348 2 0.011
fin development GO:0033333 77 0.011
Zebrafish
regulation of transporter activity GO:0032409 2 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
tube morphogenesis GO:0035239 349 0.011
regulation of calcium ion transport GO:0051924 2 0.011
sensory perception of smell GO:0007608 2 0.011
response to food GO:0032094 1 0.011
epithelial cell differentiation GO:0030855 116 0.011
regulation of protein metabolic process GO:0051246 56 0.011
locomotory behavior GO:0007626 34 0.011
regulation of sodium ion transport GO:0002028 2 0.011
endoplasmic reticulum unfolded protein response GO:0030968 2 0.011
positive regulation of protein metabolic process GO:0051247 23 0.011
negative regulation of metabolic process GO:0009892 86 0.010
response to hexose GO:0009746 3 0.010
organic substance catabolic process GO:1901575 28 0.010
posterior lateral line nerve glial cell differentiation GO:0048931 5 0.010
chemical homeostasis GO:0048878 49 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.010
glucose homeostasis GO:0042593 1 0.010
striated muscle cell development GO:0055002 108 0.010
Zebrafish
lymphocyte proliferation GO:0046651 1 0.010
cellular component morphogenesis GO:0032989 336 0.010
Zebrafish
regulation of programmed cell death GO:0043067 101 0.010
blood vessel development GO:0001568 246 0.010
transcription from rna polymerase ii promoter GO:0006366 80 0.010

cx35 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
retinal disease DOID:5679 0 0.017
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017
nervous system disease DOID:863 0 0.017
eye disease DOID:5614 0 0.017