Danio rerio

234 known processes

cxcl12a

chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)

(Aliases: sdf1a,wu:fc16h12,sdf-1a,SDF-1,wu:fa55e10,wu:fj84c02,cxcl12,MGC123091)

cxcl12a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell projection organization GO:0030030 284 0.948
head development GO:0060322 303 0.946
negative regulation of granulocyte chemotaxis GO:0071623 3 0.923
negative regulation of neutrophil chemotaxis GO:0090024 3 0.860
negative regulation of neutrophil migration GO:1902623 3 0.818
forebrain development GO:0030900 96 0.781
tube morphogenesis GO:0035239 349 0.764
neuron projection development GO:0031175 180 0.694
epithelial tube morphogenesis GO:0060562 148 0.686
Mouse
negative regulation of leukocyte chemotaxis GO:0002689 3 0.659
regulation of epithelial cell proliferation GO:0050678 3 0.646
cell morphogenesis involved in differentiation GO:0000904 195 0.628
system process GO:0003008 185 0.610
striated muscle tissue development GO:0014706 110 0.605
negative regulation of developmental process GO:0051093 65 0.590
g protein coupled receptor signaling pathway GO:0007186 74 0.588
regulation of neutrophil migration GO:1902622 6 0.581
positive regulation of axon guidance GO:1902669 1 0.556
sensory organ development GO:0007423 393 0.542
negative regulation of cell communication GO:0010648 96 0.541
Human
embryonic organ morphogenesis GO:0048562 274 0.509
response to external stimulus GO:0009605 264 0.502
multicellular organismal signaling GO:0035637 22 0.491
positive regulation of biological process GO:0048518 253 0.481
embryonic organ development GO:0048568 381 0.450
heart morphogenesis GO:0003007 156 0.445
digestive system development GO:0055123 289 0.430
cell surface receptor signaling pathway GO:0007166 325 0.422
Human
brain development GO:0007420 293 0.408
response to abiotic stimulus GO:0009628 122 0.406
central nervous system myelination GO:0022010 2 0.402
cell morphogenesis GO:0000902 289 0.385
heart development GO:0007507 313 0.374
response to organic substance GO:0010033 153 0.373
Human
ensheathment of neurons GO:0007272 18 0.366
negative regulation of cell cycle GO:0045786 14 0.342
organonitrogen compound metabolic process GO:1901564 74 0.332
response to biotic stimulus GO:0009607 97 0.331
female gonad development GO:0008585 4 0.326
blood circulation GO:0008015 87 0.310
regulation of response to stimulus GO:0048583 269 0.308
nuclear transport GO:0051169 4 0.306
neuron differentiation GO:0030182 353 0.301
lateral line development GO:0048882 66 0.298
digestive tract development GO:0048565 265 0.296
regulation of membrane potential GO:0042391 23 0.294
regulation of developmental process GO:0050793 247 0.291
urogenital system development GO:0001655 97 0.289
myelination GO:0042552 18 0.287
positive regulation of cellular amine metabolic process GO:0033240 0 0.282
axonogenesis GO:0007409 152 0.278
cardiac muscle tissue development GO:0048738 48 0.268
negative regulation of cell differentiation GO:0045596 46 0.263
positive regulation of epithelial cell proliferation GO:0050679 1 0.262
female sex differentiation GO:0046660 4 0.261
extrinsic apoptotic signaling pathway GO:0097191 3 0.248
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.247
regulation of gene expression GO:0010468 265 0.244
muscle tissue development GO:0060537 110 0.244
determination of heart left right asymmetry GO:0061371 117 0.242
regulation of cellular amino acid metabolic process GO:0006521 0 0.239
cell projection morphogenesis GO:0048858 244 0.238
developmental growth involved in morphogenesis GO:0060560 86 0.236
ameboidal type cell migration GO:0001667 143 0.235
myeloid leukocyte migration GO:0097529 12 0.235
ear development GO:0043583 127 0.232
response to organic cyclic compound GO:0014070 51 0.231
regulation of multicellular organismal process GO:0051239 277 0.230
central nervous system development GO:0007417 387 0.225
organic acid metabolic process GO:0006082 31 0.225
single organism localization GO:1902578 225 0.224
development of primary female sexual characteristics GO:0046545 4 0.222
aging GO:0007568 2 0.219
telencephalon development GO:0021537 14 0.217
nucleocytoplasmic transport GO:0006913 4 0.214
signal transduction GO:0007165 455 0.210
Human
response to lipid GO:0033993 60 0.202
chemotaxis GO:0006935 104 0.200
regulation of cellular amine metabolic process GO:0033238 0 0.196
segmentation GO:0035282 97 0.196
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.196
cellular amino acid metabolic process GO:0006520 7 0.193
embryo development ending in birth or egg hatching GO:0009792 271 0.187
circulatory system process GO:0003013 87 0.185
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.185
embryonic heart tube morphogenesis GO:0003143 108 0.183
response to steroid hormone GO:0048545 35 0.183
negative regulation of protein transport GO:0051224 3 0.183
protein import GO:0017038 3 0.180
innervation GO:0060384 3 0.179
regionalization GO:0003002 274 0.178
cytokine mediated signaling pathway GO:0019221 7 0.176
Human
eye development GO:0001654 277 0.173
protein localization to nucleus GO:0034504 3 0.171
cell part morphogenesis GO:0032990 246 0.170
response to radiation GO:0009314 51 0.170
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.169
response to glucocorticoid GO:0051384 1 0.164
positive regulation of chemotaxis GO:0050921 5 0.164
growth GO:0040007 174 0.162
cellular amine metabolic process GO:0044106 2 0.155
neuron development GO:0048666 262 0.155
biological adhesion GO:0022610 40 0.154
Human
regulation of cell differentiation GO:0045595 142 0.152
ovarian follicle development GO:0001541 2 0.152
regulation of biosynthetic process GO:0009889 250 0.150
response to stress GO:0006950 263 0.148
regulation of embryonic development GO:0045995 47 0.148
cellular response to organic substance GO:0071310 105 0.145
Human
developmental maturation GO:0021700 34 0.142
regulation of protein transport GO:0051223 3 0.139
gene expression GO:0010467 252 0.138
stem cell differentiation GO:0048863 117 0.138
positive regulation of nucleic acid templated transcription GO:1903508 57 0.136
negative regulation of signaling GO:0023057 96 0.136
Human
localization of cell GO:0051674 244 0.134
rna metabolic process GO:0016070 219 0.129
response to chemical GO:0042221 320 0.129
muscle cell differentiation GO:0042692 139 0.129
muscle structure development GO:0061061 196 0.129
response to hormone GO:0009725 48 0.129
positive regulation of cell motility GO:2000147 11 0.127
larval development GO:0002164 2 0.127
positive regulation of positive chemotaxis GO:0050927 4 0.125
glial cell migration GO:0008347 3 0.122
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.118
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.117
transport GO:0006810 220 0.117
regulation of nucleic acid templated transcription GO:1903506 213 0.117
lymph vessel morphogenesis GO:0036303 25 0.113
retinal ganglion cell axon guidance GO:0031290 35 0.113
chordate embryonic development GO:0043009 271 0.112
hepaticobiliary system development GO:0061008 98 0.111
cellular component morphogenesis GO:0032989 336 0.108
endodermal digestive tract morphogenesis GO:0061031 2 0.108
generation of neurons GO:0048699 385 0.108
adult behavior GO:0030534 2 0.108
regulation of programmed cell death GO:0043067 101 0.107
Human
transmission of nerve impulse GO:0019226 19 0.107
regulation of localization GO:0032879 104 0.106
positive regulation of response to stimulus GO:0048584 80 0.102
regulation of cell death GO:0010941 103 0.101
Human
cell fate specification GO:0001708 68 0.101
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.100
morphogenesis of an epithelium GO:0002009 333 0.099
Mouse
homeostatic process GO:0042592 142 0.096
reproduction GO:0000003 40 0.095
heart looping GO:0001947 94 0.094
negative regulation of response to stimulus GO:0048585 104 0.094
regulation of establishment of protein localization GO:0070201 4 0.093
regulation of chemotaxis GO:0050920 18 0.092
protein targeting to nucleus GO:0044744 3 0.092
regulation of erk1 and erk2 cascade GO:0070372 4 0.090
behavior GO:0007610 74 0.090
myeloid cell differentiation GO:0030099 86 0.088
negative regulation of signal transduction GO:0009968 94 0.087
Human
regulation of multicellular organismal development GO:2000026 223 0.087
retinal metabolic process GO:0042574 3 0.087
cellular response to chemical stimulus GO:0070887 157 0.086
nuclear export GO:0051168 1 0.086
axon development GO:0061564 166 0.086
nucleic acid templated transcription GO:0097659 181 0.084
cellular macromolecule biosynthetic process GO:0034645 224 0.084
positive regulation of transcription dna templated GO:0045893 57 0.083
cellular ketone metabolic process GO:0042180 11 0.082
regulation of cytoplasmic transport GO:1903649 4 0.081
regulation of endothelial cell proliferation GO:0001936 1 0.079
cellular component movement GO:0006928 335 0.078
multicellular organism growth GO:0035264 4 0.078
blood vessel development GO:0001568 246 0.077
Zebrafish Mouse
programmed cell death GO:0012501 119 0.077
Human
regulation of catenin import into nucleus GO:0035412 2 0.076
neutrophil chemotaxis GO:0030593 10 0.076
anterior posterior pattern specification GO:0009952 152 0.076
lens development in camera type eye GO:0002088 22 0.075
protein stabilization GO:0050821 2 0.074
embryonic heart tube left right pattern formation GO:0060971 5 0.074
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.074
response to external biotic stimulus GO:0043207 97 0.074
sensory organ morphogenesis GO:0090596 200 0.073
lymphoid lineage cell migration into thymus GO:0097535 4 0.073
multicellular organismal response to stress GO:0033555 2 0.072
negative regulation of cell adhesion GO:0007162 6 0.072
Human
erk1 and erk2 cascade GO:0070371 4 0.072
peptidyl serine phosphorylation GO:0018105 1 0.070
response to drug GO:0042493 3 0.069
negative regulation of mitotic cell cycle GO:0045930 11 0.069
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.068
multicellular organismal reproductive process GO:0048609 35 0.067
ovulation cycle GO:0042698 2 0.067
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.067
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.066
protein import into nucleus GO:0006606 3 0.066
induction of positive chemotaxis GO:0050930 4 0.066
kidney development GO:0001822 92 0.065
embryonic heart tube development GO:0035050 133 0.065
regulation of system process GO:0044057 40 0.065
cognition GO:0050890 1 0.065
liver development GO:0001889 96 0.064
cellular response to nutrient levels GO:0031669 2 0.064
neuronal action potential GO:0019228 18 0.063
heart process GO:0003015 71 0.063
small molecule metabolic process GO:0044281 77 0.062
specification of symmetry GO:0009799 204 0.060
negative regulation of myeloid cell differentiation GO:0045638 1 0.060
nephron epithelium morphogenesis GO:0072088 1 0.060
regulation of cell cycle GO:0051726 52 0.060
regulation of behavior GO:0050795 24 0.060
regulation of establishment of planar polarity GO:0090175 4 0.058
regulation of reproductive process GO:2000241 4 0.058
transcription dna templated GO:0006351 181 0.058
regulation of protein localization to nucleus GO:1900180 2 0.057
regulation of cell growth GO:0001558 29 0.057
posterior lateral line neuromast primordium migration GO:0048920 12 0.056
mechanosensory lateral line system development GO:0048881 49 0.056
negative regulation of leukocyte migration GO:0002686 3 0.056
negative regulation of stem cell differentiation GO:2000737 2 0.056
positive regulation of muscle cell differentiation GO:0051149 1 0.055
Mouse
cellular component biogenesis GO:0044085 178 0.055
negative regulation of cell death GO:0060548 60 0.055
Human
oxoacid metabolic process GO:0043436 31 0.054
limbic system development GO:0021761 16 0.053
myeloid cell development GO:0061515 32 0.052
ovulation cycle process GO:0022602 2 0.052
single organism nuclear import GO:1902593 3 0.051
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.051
apoptotic process GO:0006915 116 0.050
Human
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.050
axon ensheathment in central nervous system GO:0032291 2 0.050
neuron projection extension GO:1990138 45 0.050
negative regulation of multicellular organismal process GO:0051241 69 0.049
gastrulation GO:0007369 208 0.049
cell proliferation GO:0008283 80 0.049
posterior lateral line system development GO:0048915 46 0.049
cellular nitrogen compound biosynthetic process GO:0044271 218 0.049
regulation of transport GO:0051049 45 0.048
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.048
regulation of nucleocytoplasmic transport GO:0046822 2 0.047
nephron morphogenesis GO:0072028 2 0.047
renal system development GO:0072001 94 0.047
cellular response to stress GO:0033554 62 0.046
Human
sensory system development GO:0048880 76 0.046
gland development GO:0048732 143 0.046
cellular response to starvation GO:0009267 1 0.046
lymph vessel development GO:0001945 27 0.046
regulation of biological quality GO:0065008 263 0.046
regulation of anatomical structure size GO:0090066 33 0.045
regulation of erythrocyte differentiation GO:0045646 2 0.045
locomotory behavior GO:0007626 34 0.045
hematopoietic or lymphoid organ development GO:0048534 191 0.044
hypothalamus development GO:0021854 14 0.044
axis elongation involved in somitogenesis GO:0090245 2 0.043
regulation of cellular biosynthetic process GO:0031326 245 0.043
rna biosynthetic process GO:0032774 181 0.043
regulation of binding GO:0051098 3 0.042
regulation of cell proliferation GO:0042127 37 0.042
cell migration GO:0016477 237 0.042
organic substance transport GO:0071702 58 0.042
regulation of rna metabolic process GO:0051252 224 0.042
regulation of wound healing GO:0061041 2 0.042
regulation of dna replication GO:0006275 3 0.042
transcription from rna polymerase ii promoter GO:0006366 80 0.041
establishment of protein localization to organelle GO:0072594 4 0.041
positive regulation of apoptotic process GO:0043065 29 0.041
regulation of positive chemotaxis GO:0050926 4 0.041
carboxylic acid metabolic process GO:0019752 22 0.041
response to corticosteroid GO:0031960 1 0.040
developmental cell growth GO:0048588 52 0.040
cell cycle g1 s phase transition GO:0044843 1 0.040
cellular response to extracellular stimulus GO:0031668 2 0.040
regulation of intracellular protein transport GO:0033157 3 0.039
dorsal ventral pattern formation GO:0009953 125 0.039
protein metabolic process GO:0019538 183 0.039
negative regulation of map kinase activity GO:0043407 2 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.039
embryonic digestive tract morphogenesis GO:0048557 3 0.039
dendrite guidance GO:0070983 0 0.038
striated muscle cell differentiation GO:0051146 129 0.038
catenin import into nucleus GO:0035411 2 0.038
phagocytosis GO:0006909 3 0.037
positive regulation of rna metabolic process GO:0051254 59 0.037
regulation of synapse organization GO:0050807 3 0.037
morphogenesis of a branching structure GO:0001763 21 0.037
Mouse
tissue regeneration GO:0042246 74 0.037
regulation of anatomical structure morphogenesis GO:0022603 130 0.036
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.036
cellular amide metabolic process GO:0043603 4 0.036
regulation of canonical wnt signaling pathway GO:0060828 34 0.036
axonogenesis involved in innervation GO:0060385 1 0.036
pronephros development GO:0048793 69 0.036
embryonic viscerocranium morphogenesis GO:0048703 52 0.036
positive regulation of leukocyte migration GO:0002687 2 0.036
Human
olfactory lobe development GO:0021988 4 0.036
cell adhesion GO:0007155 40 0.036
Human
patterning of blood vessels GO:0001569 15 0.036
Mouse
action potential GO:0001508 19 0.036
positive regulation of cell death GO:0010942 29 0.036
regulation of macromolecule metabolic process GO:0060255 317 0.036
digestive tract morphogenesis GO:0048546 231 0.036
positive regulation of cellular component movement GO:0051272 11 0.035
glomerular epithelial cell fate commitment GO:0072314 4 0.035
neuron projection morphogenesis GO:0048812 161 0.035
negative regulation of mitosis GO:0045839 3 0.035
positive regulation of gene expression GO:0010628 71 0.034
regulation of protein binding GO:0043393 3 0.034
cell death GO:0008219 121 0.034
Human
meiotic nuclear division GO:0007126 4 0.034
diencephalon development GO:0021536 58 0.034
central nervous system neuron development GO:0021954 29 0.034
motor neuron axon guidance GO:0008045 23 0.034
Mouse
glial cell differentiation GO:0010001 42 0.034
negative regulation of leukocyte differentiation GO:1902106 1 0.034
cellular response to external stimulus GO:0071496 2 0.034
regulation of axon extension GO:0030516 24 0.033
epidermis development GO:0008544 48 0.033
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 1 0.033
muscle organ development GO:0007517 101 0.033
cell growth GO:0016049 57 0.033
regulation of immune system process GO:0002682 34 0.033
neurological system process GO:0050877 62 0.033
response to endogenous stimulus GO:0009719 83 0.033
death GO:0016265 121 0.033
Human
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.032
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.032
hematopoietic stem cell migration GO:0035701 4 0.032
response to other organism GO:0051707 97 0.032
heart contraction GO:0060047 71 0.031
organic substance biosynthetic process GO:1901576 289 0.031
positive regulation of cell cycle GO:0045787 3 0.031
olfactory bulb axon guidance GO:0071678 3 0.031
regulation of apoptotic process GO:0042981 98 0.031
Human
aromatic compound biosynthetic process GO:0019438 217 0.030
nitrogen compound metabolic process GO:0006807 319 0.030
negative regulation of endodermal cell differentiation GO:1903225 8 0.030
regulation of protein targeting GO:1903533 2 0.030
negative regulation of hormone secretion GO:0046888 2 0.030
bmp signaling pathway GO:0030509 52 0.029
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.029
olfactory bulb development GO:0021772 4 0.029
lens fiber cell development GO:0070307 3 0.029
receptor internalization GO:0031623 2 0.029
regulation of cellular protein metabolic process GO:0032268 52 0.029
neural tube formation GO:0001841 16 0.028
leukocyte proliferation GO:0070661 1 0.028
Mouse
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.028
negative regulation of neuron differentiation GO:0045665 10 0.028
protein modification process GO:0036211 100 0.028
ossification GO:0001503 23 0.027
regulation of protein ubiquitination GO:0031396 3 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.027
cardiocyte differentiation GO:0035051 44 0.027
regulation of nervous system development GO:0051960 90 0.027
positive regulation of neuron migration GO:2001224 2 0.027
regulation of mitotic cell cycle GO:0007346 25 0.027
tube closure GO:0060606 1 0.027
venous blood vessel development GO:0060841 9 0.026
positive regulation of striated muscle tissue development GO:0045844 1 0.026
regulation of dna metabolic process GO:0051052 11 0.026
neural tube development GO:0021915 62 0.026
biomineral tissue development GO:0031214 13 0.026
dopaminergic neuron differentiation GO:0071542 14 0.026
blood vessel morphogenesis GO:0048514 216 0.026
Zebrafish Mouse
cell chemotaxis GO:0060326 17 0.026
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.025
regulation of gastrulation GO:0010470 24 0.025
axon ensheathment GO:0008366 18 0.025
regulation of cell projection organization GO:0031344 44 0.025
oligodendrocyte differentiation GO:0048709 23 0.025
extracellular matrix organization GO:0030198 27 0.025
regulation of inner ear receptor cell differentiation GO:2000980 1 0.025
regulation of protein phosphorylation GO:0001932 18 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.025
glial cell development GO:0021782 20 0.024
female gamete generation GO:0007292 14 0.024
negative regulation of phosphate metabolic process GO:0045936 13 0.024
negative regulation of cell development GO:0010721 26 0.024
amine metabolic process GO:0009308 2 0.024
determination of bilateral symmetry GO:0009855 204 0.024
regulation of multicellular organism growth GO:0040014 4 0.024
negative regulation of cytoplasmic transport GO:1903650 2 0.024
camera type eye development GO:0043010 222 0.024
negative regulation of behavior GO:0048521 6 0.024
negative regulation of endodermal cell fate specification GO:0042664 8 0.024
response to estrogen GO:0043627 27 0.024
organic cyclic compound metabolic process GO:1901360 301 0.023
regeneration GO:0031099 91 0.023
inner ear development GO:0048839 126 0.023
mesenchyme development GO:0060485 127 0.023
negative regulation of response to dna damage stimulus GO:2001021 3 0.023
Human
positive regulation of macromolecule metabolic process GO:0010604 93 0.023
signal transduction in absence of ligand GO:0038034 1 0.023
endodermal cell fate determination GO:0007493 2 0.023
single organism metabolic process GO:0044710 217 0.023
cranial nerve development GO:0021545 42 0.022
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.022
Mouse
nuclear import GO:0051170 3 0.022
positive regulation of developmental process GO:0051094 50 0.022
stem cell maintenance GO:0019827 4 0.022
ear morphogenesis GO:0042471 64 0.022
locomotion GO:0040011 313 0.022
regulation of neurogenesis GO:0050767 87 0.022
regulation of mechanoreceptor differentiation GO:0045631 1 0.022
enzyme linked receptor protein signaling pathway GO:0007167 106 0.022
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.022
cellular protein metabolic process GO:0044267 129 0.022
regulation of organ morphogenesis GO:2000027 35 0.022
cellular response to endogenous stimulus GO:0071495 68 0.022
nephron tubule morphogenesis GO:0072078 1 0.021
germ cell development GO:0007281 22 0.021
Mouse
regulation of stem cell differentiation GO:2000736 4 0.021
regulation of ion transmembrane transporter activity GO:0032412 2 0.021
syncytium formation GO:0006949 12 0.021
Mouse
regulation of cellular ketone metabolic process GO:0010565 7 0.021
positive regulation of locomotion GO:0040017 14 0.021
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.021
antimicrobial humoral response GO:0019730 2 0.021
canonical wnt signaling pathway GO:0060070 48 0.021
response to oxygen containing compound GO:1901700 55 0.021
negative regulation of non canonical wnt signaling pathway GO:2000051 1 0.021
regulation of myelination GO:0031641 1 0.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.021
wnt signaling pathway GO:0016055 80 0.021
cellular macromolecule localization GO:0070727 21 0.021
positive regulation of cellular process GO:0048522 201 0.020
taxis GO:0042330 109 0.020
phosphorylation GO:0016310 69 0.020
carbohydrate derivative metabolic process GO:1901135 61 0.020
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
regulation of transcription dna templated GO:0006355 213 0.020
positive regulation of cytokine production GO:0001819 2 0.020
embryonic skeletal system development GO:0048706 97 0.020
establishment of localization GO:0051234 244 0.020
regulation of cell cell adhesion GO:0022407 13 0.020
Human
cellular response to radiation GO:0071478 4 0.020
immune system process GO:0002376 241 0.020
somitogenesis GO:0001756 87 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
regulation of response to external stimulus GO:0032101 31 0.019
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.019
response to starvation GO:0042594 5 0.019
negative regulation of kinase activity GO:0033673 4 0.019
response to nutrient levels GO:0031667 10 0.019
regulation of bmp signaling pathway GO:0030510 39 0.019
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.019
negative regulation of protein import into nucleus GO:0042308 2 0.019
primary neural tube formation GO:0014020 1 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.019
regulation of cellular response to stress GO:0080135 20 0.019
Human
negative regulation of epithelial cell proliferation GO:0050680 1 0.018
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.018
regulation of glial cell differentiation GO:0045685 4 0.018
lateral line system development GO:0048925 76 0.018
skeletal muscle organ development GO:0060538 78 0.018
rhombomere 5 morphogenesis GO:0021664 1 0.018
positive regulation of catabolic process GO:0009896 4 0.018
gamete generation GO:0007276 33 0.018
single organismal cell cell adhesion GO:0016337 29 0.018
Human
protein phosphorylation GO:0006468 47 0.018
negative regulation of chemotaxis GO:0050922 4 0.018
nephron tubule epithelial cell differentiation GO:0072160 1 0.018
negative regulation of neurogenesis GO:0050768 20 0.017
regulation of axonogenesis GO:0050770 32 0.017
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
forebrain regionalization GO:0021871 4 0.017
positive regulation of wound healing GO:0090303 1 0.017
epithelial cell differentiation GO:0030855 116 0.017
otolith development GO:0048840 32 0.017
gabaergic neuron differentiation GO:0097154 2 0.017
peripheral nervous system development GO:0007422 55 0.017
regulation of oxidative stress induced cell death GO:1903201 2 0.017
cell cell signaling GO:0007267 52 0.017
hormone transport GO:0009914 2 0.017
cilium organization GO:0044782 71 0.017
regulation of cell shape GO:0008360 1 0.017
regulation of cell development GO:0060284 100 0.017
synaptic vesicle localization GO:0097479 1 0.017
cellular component maintenance GO:0043954 3 0.017
skeletal system development GO:0001501 181 0.017
extraocular skeletal muscle development GO:0002074 3 0.017
embryonic limb morphogenesis GO:0030326 2 0.017
response to light stimulus GO:0009416 46 0.017
somatic muscle development GO:0007525 4 0.017

cxcl12a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease by infectious agent DOID:0050117 0 0.159
Human
charcot marie tooth disease type 4 DOID:0050541 0 0.045
neuromuscular disease DOID:440 0 0.045
disease of anatomical entity DOID:7 0 0.045
charcot marie tooth disease DOID:10595 0 0.045
nervous system disease DOID:863 0 0.045
neuropathy DOID:870 0 0.045
disease of cellular proliferation DOID:14566 0 0.042
reproductive organ cancer DOID:193 0 0.038
female reproductive organ cancer DOID:120 0 0.038
cancer DOID:162 0 0.038
organ system cancer DOID:0050686 0 0.038
urinary system cancer DOID:3996 0 0.017