Danio rerio

69 known processes

cxcr4a

chemokine (C-X-C motif) receptor 4a

(Aliases: cb824)

cxcr4a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
blood vessel morphogenesis GO:0048514 216 0.998
blood vessel development GO:0001568 246 0.984
digestive tract morphogenesis GO:0048546 231 0.965
digestive tract development GO:0048565 265 0.963
angiogenesis GO:0001525 158 0.957
heart jogging GO:0003146 40 0.955
vasculature development GO:0001944 278 0.940
brain development GO:0007420 293 0.932
Zebrafish Mouse Rat
locomotion GO:0040011 313 0.919
biosynthetic process GO:0009058 294 0.910
negative regulation of biological process GO:0048519 304 0.907
Zebrafish
aorta development GO:0035904 4 0.894
epithelial cell development GO:0002064 42 0.894
Rat
protein import into nucleus GO:0006606 3 0.867
Zebrafish
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.856
regulation of primary metabolic process GO:0080090 311 0.840
regulation of multicellular organismal process GO:0051239 277 0.831
Zebrafish Mouse
negative regulation of cellular process GO:0048523 283 0.811
Zebrafish
response to chemical GO:0042221 320 0.803
Human Zebrafish Mouse Rat
formation of primary germ layer GO:0001704 62 0.803
gastrulation GO:0007369 208 0.795
endoderm formation GO:0001706 29 0.792
negative regulation of neutrophil migration GO:1902623 3 0.781
Zebrafish
endothelial cell development GO:0001885 12 0.778
tube morphogenesis GO:0035239 349 0.778
forebrain development GO:0030900 96 0.778
Zebrafish Rat
positive regulation of biological process GO:0048518 253 0.768
Zebrafish Mouse
localization of cell GO:0051674 244 0.767
cellular component movement GO:0006928 335 0.740
organic cyclic compound metabolic process GO:1901360 301 0.734
cell migration GO:0016477 237 0.729
ameboidal type cell migration GO:0001667 143 0.714
single organism localization GO:1902578 225 0.705
Zebrafish Rat
sensory organ development GO:0007423 393 0.692
cell migration involved in gastrulation GO:0042074 79 0.680
striated muscle cell differentiation GO:0051146 129 0.678
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.659
segmentation GO:0035282 97 0.646
organelle assembly GO:0070925 110 0.639
mesenchyme development GO:0060485 127 0.615
protein localization to nucleus GO:0034504 3 0.613
Zebrafish
regionalization GO:0003002 274 0.610
Zebrafish
epithelial cell morphogenesis GO:0003382 2 0.603
diencephalon development GO:0021536 58 0.591
negative regulation of leukocyte chemotaxis GO:0002689 3 0.577
Zebrafish
developmental growth GO:0048589 166 0.560
Zebrafish
cell cycle GO:0007049 93 0.559
somitogenesis GO:0001756 87 0.558
nucleocytoplasmic transport GO:0006913 4 0.551
Zebrafish
epithelial cell differentiation GO:0030855 116 0.518
Rat
cellular nitrogen compound metabolic process GO:0034641 290 0.500
cell surface receptor signaling pathway GO:0007166 325 0.493
Human Zebrafish Rat
response to external stimulus GO:0009605 264 0.486
Human Zebrafish Mouse Rat
mesenchymal cell development GO:0014031 78 0.485
dorsal aorta morphogenesis GO:0035912 3 0.484
regulation of catenin import into nucleus GO:0035412 2 0.483
Zebrafish
cellular biosynthetic process GO:0044249 286 0.481
cellular nitrogen compound biosynthetic process GO:0044271 218 0.476
striated muscle cell development GO:0055002 108 0.473
establishment of protein localization to organelle GO:0072594 4 0.468
Zebrafish
cell motility GO:0048870 244 0.459
immune system process GO:0002376 241 0.459
Zebrafish Mouse
negative regulation of granulocyte chemotaxis GO:0071623 3 0.449
Zebrafish
organelle organization GO:0006996 227 0.447
establishment of localization GO:0051234 244 0.446
Zebrafish Rat
sprouting angiogenesis GO:0002040 53 0.440
gene expression GO:0010467 252 0.440
dorsal ventral pattern formation GO:0009953 125 0.435
Zebrafish
endoderm development GO:0007492 49 0.429
regulation of protein localization to nucleus GO:1900180 2 0.425
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.420
patterning of blood vessels GO:0001569 15 0.416
Mouse
nitrogen compound metabolic process GO:0006807 319 0.415
cellular component morphogenesis GO:0032989 336 0.414
neuron development GO:0048666 262 0.398
Zebrafish Mouse Rat
hepaticobiliary system development GO:0061008 98 0.395
morphogenesis of an epithelium GO:0002009 333 0.394
Mouse
endothelium development GO:0003158 25 0.390
transport GO:0006810 220 0.384
Zebrafish Rat
radial glial cell differentiation GO:0060019 2 0.382
organic cyclic compound biosynthetic process GO:1901362 223 0.382
nucleobase containing compound biosynthetic process GO:0034654 205 0.367
stem cell differentiation GO:0048863 117 0.366
single organism metabolic process GO:0044710 217 0.359
regulation of protein targeting GO:1903533 2 0.358
Zebrafish
heterocycle metabolic process GO:0046483 290 0.356
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.353
cellular component biogenesis GO:0044085 178 0.350
immune system development GO:0002520 191 0.344
cellular macromolecule biosynthetic process GO:0034645 224 0.342
regulation of gene expression GO:0010468 265 0.342
organic substance biosynthetic process GO:1901576 289 0.339
regulation of bmp signaling pathway GO:0030510 39 0.339
cellular aromatic compound metabolic process GO:0006725 295 0.338
negative regulation of neutrophil chemotaxis GO:0090024 3 0.331
Zebrafish
protein targeting to nucleus GO:0044744 3 0.331
Zebrafish
actin filament based process GO:0030029 64 0.327
odontogenesis of dentin containing tooth GO:0042475 1 0.321
cell morphogenesis GO:0000902 289 0.321
notochord morphogenesis GO:0048570 17 0.321
neural crest cell differentiation GO:0014033 72 0.321
digestive system development GO:0055123 289 0.320
regulation of intracellular signal transduction GO:1902531 57 0.318
muscle structure development GO:0061061 196 0.318
regulation of biosynthetic process GO:0009889 250 0.314
regulation of nitrogen compound metabolic process GO:0051171 251 0.313
morphogenesis of a branching epithelium GO:0061138 16 0.312
Mouse
regulation of transcription dna templated GO:0006355 213 0.312
inner ear development GO:0048839 126 0.305
somite development GO:0061053 96 0.300
regulation of establishment of protein localization GO:0070201 4 0.286
Zebrafish
response to organic substance GO:0010033 153 0.279
Human Zebrafish Rat
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.277
nuclear transport GO:0051169 4 0.274
Zebrafish
inner ear morphogenesis GO:0042472 63 0.273
rna metabolic process GO:0016070 219 0.273
lateral line development GO:0048882 66 0.272
Zebrafish
single organism reproductive process GO:0044702 40 0.271
Zebrafish Mouse
eye development GO:0001654 277 0.266
positive regulation of cell cycle GO:0045787 3 0.265
enzyme linked receptor protein signaling pathway GO:0007167 106 0.261
single organism nuclear import GO:1902593 3 0.257
Zebrafish
regulation of response to stimulus GO:0048583 269 0.252
Human Zebrafish Rat
positive regulation of cellular process GO:0048522 201 0.249
Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.248
Zebrafish Mouse
mitotic cell cycle GO:0000278 64 0.247
head development GO:0060322 303 0.245
Zebrafish Mouse Rat
sensory system development GO:0048880 76 0.244
Zebrafish
endothelial cell differentiation GO:0045446 20 0.243
chordate embryonic development GO:0043009 271 0.241
growth GO:0040007 174 0.240
Zebrafish
mesenchymal cell differentiation GO:0048762 87 0.238
kidney development GO:0001822 92 0.238
positive regulation of neural precursor cell proliferation GO:2000179 1 0.233
negative regulation of epithelial cell proliferation GO:0050680 1 0.232
response to external biotic stimulus GO:0043207 97 0.231
Zebrafish
macromolecular complex subunit organization GO:0043933 74 0.230
regulation of cellular biosynthetic process GO:0031326 245 0.226
spinal cord radial glial cell differentiation GO:0021531 2 0.223
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.222
branching morphogenesis of an epithelial tube GO:0048754 15 0.218
Mouse
regulation of signaling GO:0023051 235 0.217
positive regulation of metabolic process GO:0009893 108 0.216
embryonic organ development GO:0048568 381 0.215
response to wounding GO:0009611 116 0.215
Zebrafish
lymphoid lineage cell migration into thymus GO:0097535 4 0.215
negative regulation of catenin import into nucleus GO:0035414 2 0.209
Zebrafish
lymphangiogenesis GO:0001946 25 0.205
regulation of cell proliferation GO:0042127 37 0.204
response to other organism GO:0051707 97 0.200
Zebrafish
protein import GO:0017038 3 0.199
Zebrafish
renal system development GO:0072001 94 0.190
regulation of rna metabolic process GO:0051252 224 0.189
nucleic acid metabolic process GO:0090304 244 0.186
cytoskeleton organization GO:0007010 96 0.186
t cell activation GO:0042110 6 0.185
Mouse
response to stress GO:0006950 263 0.183
Human Zebrafish
positive regulation of positive chemotaxis GO:0050927 4 0.183
Zebrafish
endodermal digestive tract morphogenesis GO:0061031 2 0.182
cellular macromolecule metabolic process GO:0044260 391 0.182
cellular response to chemical stimulus GO:0070887 157 0.181
Human Zebrafish Rat
determination of left right asymmetry in diencephalon GO:0035462 4 0.180
fin morphogenesis GO:0033334 53 0.180
reproduction GO:0000003 40 0.179
Zebrafish Mouse
appendage morphogenesis GO:0035107 56 0.176
regulation of protein import into nucleus GO:0042306 2 0.172
Zebrafish
regulation of nucleocytoplasmic transport GO:0046822 2 0.172
Zebrafish
regulation of phosphorus metabolic process GO:0051174 43 0.170
negative regulation of cell differentiation GO:0045596 46 0.169
heterocycle biosynthetic process GO:0018130 215 0.169
single organism transport GO:0044765 206 0.168
Zebrafish Rat
retinal ganglion cell axon guidance GO:0031290 35 0.164
Zebrafish
notochord development GO:0030903 54 0.164
determination of left right asymmetry in nervous system GO:0035545 4 0.162
microtubule based process GO:0007017 60 0.161
regulation of ectodermal cell fate specification GO:0042665 2 0.161
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.159
optic placode formation involved in camera type eye formation GO:0046619 3 0.156
response to biotic stimulus GO:0009607 97 0.155
Zebrafish
regulation of macromolecule biosynthetic process GO:0010556 225 0.152
nucleobase containing compound metabolic process GO:0006139 274 0.152
striated muscle tissue development GO:0014706 110 0.151
regulation of cell differentiation GO:0045595 142 0.151
Zebrafish Mouse
atrioventricular valve formation GO:0003190 3 0.149
cellular component assembly GO:0022607 170 0.146
negative regulation of multicellular organismal process GO:0051241 69 0.146
mesoderm development GO:0007498 88 0.145
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.144
negative regulation of gene expression GO:0010629 65 0.144
hypothalamus cell differentiation GO:0021979 4 0.142
regulation of retina development in camera type eye GO:1902866 2 0.142
regulation of protein transport GO:0051223 3 0.142
Zebrafish
cilium organization GO:0044782 71 0.136
negative regulation of protein phosphorylation GO:0001933 4 0.136
heart valve formation GO:0003188 4 0.134
stem cell development GO:0048864 82 0.133
regulation of cell communication GO:0010646 232 0.131
phosphorus metabolic process GO:0006793 109 0.131
wound healing GO:0042060 90 0.130
Zebrafish
convergent extension involved in gastrulation GO:0060027 71 0.130
regulation of cell cycle GO:0051726 52 0.129
aromatic compound biosynthetic process GO:0019438 217 0.128
cellular response to organic substance GO:0071310 105 0.127
Human Rat
patterning of lymph vessels GO:0060854 1 0.127
retina development in camera type eye GO:0060041 146 0.126
somite specification GO:0001757 12 0.126
dorsal aorta development GO:0035907 4 0.125
negative regulation of response to stimulus GO:0048585 104 0.125
Zebrafish
regulation of inner ear receptor cell differentiation GO:2000980 1 0.125
blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 4 0.124
macromolecule biosynthetic process GO:0009059 227 0.124
actomyosin structure organization GO:0031032 53 0.123
neural tube development GO:0021915 62 0.123
ear morphogenesis GO:0042471 64 0.121
signal transduction GO:0007165 455 0.121
Human Zebrafish Rat
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.121
muscle cell differentiation GO:0042692 139 0.121
regulation of angiogenesis GO:0045765 26 0.121
phagocytosis GO:0006909 3 0.118
cellular response to growth factor stimulus GO:0071363 39 0.115
neural crest cell development GO:0014032 62 0.115
establishment of endothelial barrier GO:0061028 3 0.115
negative regulation of cellular metabolic process GO:0031324 77 0.114
stem cell maintenance GO:0019827 4 0.114
regulation of stem cell proliferation GO:0072091 2 0.114
regulation of intracellular protein transport GO:0033157 3 0.112
Zebrafish
negative regulation of signaling GO:0023057 96 0.111
foregut morphogenesis GO:0007440 4 0.111
protein modification process GO:0036211 100 0.110
phosphorylation GO:0016310 69 0.110
nuclear import GO:0051170 3 0.110
Zebrafish
aorta morphogenesis GO:0035909 3 0.109
neuroblast proliferation GO:0007405 2 0.108
gland development GO:0048732 143 0.107
cell proliferation GO:0008283 80 0.107
Mouse
regulation of skeletal muscle tissue development GO:0048641 4 0.106
cellular response to endogenous stimulus GO:0071495 68 0.106
appendage development GO:0048736 80 0.105
endocardium formation GO:0060214 1 0.104
neuron differentiation GO:0030182 353 0.104
Zebrafish Mouse Rat
positive regulation of transport GO:0051050 2 0.103
cilium morphogenesis GO:0060271 85 0.103
phosphate containing compound metabolic process GO:0006796 108 0.103
central nervous system development GO:0007417 387 0.102
Zebrafish Mouse Rat
sexual reproduction GO:0019953 36 0.101
Zebrafish Mouse
positive regulation of biosynthetic process GO:0009891 68 0.101
regulation of rna biosynthetic process GO:2001141 213 0.100
negative regulation of cell communication GO:0010648 96 0.100
macromolecule modification GO:0043412 111 0.099
neural retina development GO:0003407 49 0.098
embryo development ending in birth or egg hatching GO:0009792 271 0.097
regulation of biomineral tissue development GO:0070167 2 0.097
camera type eye development GO:0043010 222 0.096
endodermal cell fate determination GO:0007493 2 0.095
endodermal cell differentiation GO:0035987 19 0.095
multi organism process GO:0051704 134 0.094
Zebrafish Mouse
cellular localization GO:0051641 97 0.094
Zebrafish
negative regulation of kinase activity GO:0033673 4 0.094
cardiac chamber development GO:0003205 19 0.094
regulation of eye photoreceptor cell development GO:0042478 2 0.093
cellular component assembly involved in morphogenesis GO:0010927 107 0.093
non canonical wnt signaling pathway involved in heart development GO:0061341 2 0.092
convergent extension GO:0060026 118 0.092
positive regulation of cellular metabolic process GO:0031325 94 0.092
mechanosensory lateral line system development GO:0048881 49 0.091
Zebrafish
proximal distal pattern formation GO:0009954 1 0.090
cell projection organization GO:0030030 284 0.090
Zebrafish Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.089
response to growth factor GO:0070848 39 0.089
cell cycle process GO:0022402 53 0.087
negative regulation of signal transduction GO:0009968 94 0.086
lymph vessel development GO:0001945 27 0.086
regulation of signal transduction GO:0009966 225 0.085
signal transduction by phosphorylation GO:0023014 18 0.083
blood vessel endothelial cell migration GO:0043534 18 0.083
negative regulation of blood vessel endothelial cell migration GO:0043537 1 0.082
regulation of cellular component movement GO:0051270 55 0.081
Zebrafish Mouse
eye morphogenesis GO:0048592 144 0.081
regulation of phosphorylation GO:0042325 26 0.081
single organism cell adhesion GO:0098602 29 0.081
regulation of epithelial cell proliferation GO:0050678 3 0.078
regulation of multicellular organismal development GO:2000026 223 0.078
Zebrafish Mouse
skeletal system development GO:0001501 181 0.077
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.076
morphogenesis of a branching structure GO:0001763 21 0.076
Mouse
myelin assembly GO:0032288 1 0.075
tissue regeneration GO:0042246 74 0.074
Zebrafish
larval development GO:0002164 2 0.073
negative regulation of phosphate metabolic process GO:0045936 13 0.072
regulation of oligodendrocyte differentiation GO:0048713 1 0.072
Mouse
cellular macromolecule localization GO:0070727 21 0.071
Zebrafish
regulation of myotube differentiation GO:0010830 2 0.070
oligodendrocyte differentiation GO:0048709 23 0.070
Mouse
embryonic organ morphogenesis GO:0048562 274 0.069
regulation of metabolic process GO:0019222 359 0.069
regulation of neural precursor cell proliferation GO:2000177 3 0.069
muscle tissue development GO:0060537 110 0.068
generation of neurons GO:0048699 385 0.068
Zebrafish Mouse Rat
stem cell division GO:0017145 1 0.068
epidermal cell fate specification GO:0009957 4 0.068
actin cytoskeleton organization GO:0030036 63 0.068
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.067
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.067
vasculogenesis GO:0001570 41 0.067
cell cycle g1 s phase transition GO:0044843 1 0.066
skin development GO:0043588 54 0.065
meiotic nuclear division GO:0007126 4 0.065
regulation of wnt signaling pathway involved in heart development GO:0003307 2 0.064
epidermis development GO:0008544 48 0.063
positive regulation of stem cell proliferation GO:2000648 1 0.063
cardiac atrium development GO:0003230 4 0.063
hindbrain development GO:0030902 91 0.063
response to fluid shear stress GO:0034405 2 0.062
regulation of growth GO:0040008 42 0.062
Zebrafish
negative regulation of cardiac muscle cell differentiation GO:2000726 1 0.061
negative regulation of muscle cell differentiation GO:0051148 1 0.060
epithelial to mesenchymal transition GO:0001837 21 0.060
regulation of cardiac muscle cell differentiation GO:2000725 1 0.060
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.059
nephron epithelium morphogenesis GO:0072088 1 0.059
hematopoietic or lymphoid organ development GO:0048534 191 0.057
protein metabolic process GO:0019538 183 0.057
cell projection morphogenesis GO:0048858 244 0.057
Zebrafish Mouse
astrocyte differentiation GO:0048708 1 0.057
cardiac muscle tissue development GO:0048738 48 0.057
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.057
cellular ketone metabolic process GO:0042180 11 0.057
regulation of phosphate metabolic process GO:0019220 43 0.056
activation of mapkkk activity GO:0000185 1 0.056
nitric oxide biosynthetic process GO:0006809 2 0.056
positive regulation of muscle tissue development GO:1901863 1 0.056
lymphoid lineage cell migration GO:0097534 4 0.056
anterior posterior pattern specification GO:0009952 152 0.056
atrial ventricular junction remodeling GO:0003294 2 0.055
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.055
positive regulation of catabolic process GO:0009896 4 0.055
heart valve development GO:0003170 14 0.055
positive regulation of developmental process GO:0051094 50 0.055
Mouse
regulation of biological quality GO:0065008 263 0.054
Zebrafish
spindle assembly GO:0051225 2 0.054
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.054
hematopoietic stem cell differentiation GO:0060218 20 0.053
single organism organelle organization GO:1902589 199 0.053
regulation of epithelial to mesenchymal transition GO:0010717 3 0.052
nitric oxide metabolic process GO:0046209 2 0.052
receptor internalization GO:0031623 2 0.051
positive regulation of striated muscle cell differentiation GO:0051155 1 0.051
endothelial cell morphogenesis GO:0001886 1 0.051
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.051
heart looping GO:0001947 94 0.050
regulation of mechanoreceptor differentiation GO:0045631 1 0.050
hemopoiesis GO:0030097 183 0.050
regulation of developmental process GO:0050793 247 0.050
Zebrafish Mouse
segment specification GO:0007379 12 0.050
nucleic acid templated transcription GO:0097659 181 0.050
regulation of skeletal muscle fiber development GO:0048742 2 0.050
cell death GO:0008219 121 0.049
Rat
negative regulation of metabolic process GO:0009892 86 0.049
regulation of cytokine production GO:0001817 3 0.049
pharyngeal muscle development GO:0043282 4 0.048
cellular response to stress GO:0033554 62 0.048
positive regulation of multicellular organismal process GO:0051240 52 0.047
Mouse
heart development GO:0007507 313 0.047
macromolecular complex assembly GO:0065003 35 0.047
regulation of nervous system development GO:0051960 90 0.047
Zebrafish Mouse
liver development GO:0001889 96 0.047
negative regulation of apoptotic process GO:0043066 55 0.046
determination of heart left right asymmetry GO:0061371 117 0.046
connective tissue development GO:0061448 99 0.046
endodermal cell fate commitment GO:0001711 18 0.046
embryonic heart tube morphogenesis GO:0003143 108 0.046
negative regulation of wnt signaling pathway GO:0030178 30 0.045
cartilage development GO:0051216 96 0.045
fin development GO:0033333 77 0.045
hematopoietic stem cell migration GO:0035701 4 0.044
cell cell adhesion involved in mesendodermal cell migration GO:0003370 1 0.044
wnt signaling pathway GO:0016055 80 0.044
negative regulation of developmental process GO:0051093 65 0.044
regulation of cell projection assembly GO:0060491 4 0.044
cardiocyte differentiation GO:0035051 44 0.044
peripheral nervous system development GO:0007422 55 0.043
positive regulation of epithelial cell proliferation GO:0050679 1 0.043
regeneration GO:0031099 91 0.043
Zebrafish
tissue migration GO:0090130 37 0.043
single organism cellular localization GO:1902580 46 0.043
Zebrafish
positive regulation of gene expression GO:0010628 71 0.042
positive regulation of nucleic acid templated transcription GO:1903508 57 0.042
regulation of ectoderm development GO:2000383 2 0.042
blood vessel endothelial cell differentiation GO:0060837 2 0.041
epithelial tube morphogenesis GO:0060562 148 0.041
Mouse
negative regulation of muscle tissue development GO:1901862 2 0.041
atrioventricular valve morphogenesis GO:0003181 6 0.041
regulation of cellular response to growth factor stimulus GO:0090287 35 0.041
bmp signaling pathway GO:0030509 52 0.040
intestinal epithelial cell differentiation GO:0060575 3 0.039
mitotic cell cycle process GO:1903047 48 0.039
positive regulation of cell proliferation GO:0008284 15 0.039
heart field specification GO:0003128 1 0.039
regulation of protein metabolic process GO:0051246 56 0.039
hepatocyte differentiation GO:0070365 1 0.039
cilium assembly GO:0042384 58 0.039
motor neuron axon guidance GO:0008045 23 0.038
Mouse
regulation of establishment of planar polarity GO:0090175 4 0.038
coagulation GO:0050817 13 0.038
positive regulation of cellular amine metabolic process GO:0033240 0 0.038
mononuclear cell proliferation GO:0032943 1 0.038
Mouse
endothelial cell proliferation GO:0001935 11 0.037
regulation of endothelial cell proliferation GO:0001936 1 0.037
neural tube patterning GO:0021532 33 0.037
regulation of vasculogenesis GO:2001212 1 0.036
positive regulation of cellular catabolic process GO:0031331 3 0.036
cellular protein metabolic process GO:0044267 129 0.036
mesoderm morphogenesis GO:0048332 51 0.036
positive regulation of glial cell differentiation GO:0045687 1 0.036
Mouse
regulation of epidermis development GO:0045682 2 0.036
positive regulation of muscle organ development GO:0048636 1 0.035
establishment or maintenance of cell polarity GO:0007163 29 0.035
semicircular canal development GO:0060872 24 0.035
mitotic dna damage checkpoint GO:0044773 4 0.035
cell part morphogenesis GO:0032990 246 0.035
Zebrafish Mouse
optic placode formation GO:0001743 4 0.034
epidermal cell differentiation GO:0009913 36 0.034
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.033
proepicardium development GO:0003342 4 0.033
leukocyte differentiation GO:0002521 25 0.032
lymphocyte activation GO:0046649 10 0.032
Mouse
inner ear receptor cell development GO:0060119 20 0.032
programmed cell death GO:0012501 119 0.032
Rat
spinal cord development GO:0021510 46 0.032
microtubule cytoskeleton organization GO:0000226 33 0.032
cellular response to external stimulus GO:0071496 2 0.031
axis elongation involved in somitogenesis GO:0090245 2 0.031
angioblast cell differentiation GO:0035779 2 0.031
negative regulation of leukocyte migration GO:0002686 3 0.031
Zebrafish
ectodermal cell fate specification GO:0001715 2 0.031
positive regulation of rna biosynthetic process GO:1902680 57 0.031
single organism biosynthetic process GO:0044711 71 0.031
centrosome organization GO:0051297 1 0.031
regulation of programmed cell death GO:0043067 101 0.030
Rat
cardiac atrium morphogenesis GO:0003209 2 0.030
heart morphogenesis GO:0003007 156 0.030
photoreceptor cell fate commitment GO:0046552 1 0.030
spinal cord oligodendrocyte cell differentiation GO:0021529 5 0.030
microtubule organizing center organization GO:0031023 1 0.030
protein phosphorylation GO:0006468 47 0.030
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.030
Zebrafish Mouse
spindle organization GO:0007051 5 0.029
embryonic heart tube development GO:0035050 133 0.029
meiotic spindle organization GO:0000212 1 0.029
morphogenesis of an epithelial sheet GO:0002011 49 0.029
periodic partitioning GO:0007365 1 0.029
ectodermal placode formation GO:0060788 26 0.029
regulation of molecular function GO:0065009 70 0.029
regulation of cell cycle process GO:0010564 20 0.029
urogenital system development GO:0001655 97 0.029
cell migration involved in sprouting angiogenesis GO:0002042 8 0.029
immune effector process GO:0002252 23 0.028
Zebrafish
ventricular cardiac muscle tissue development GO:0003229 3 0.028
neurological system process GO:0050877 62 0.028
regulation of response to stress GO:0080134 36 0.028
negative regulation of endothelial cell migration GO:0010596 1 0.028
regulation of heart morphogenesis GO:2000826 17 0.028
intracellular signal transduction GO:0035556 85 0.028
Human
regulation of neural retina development GO:0061074 2 0.028
glomerulus vasculature morphogenesis GO:0072103 1 0.028
negative regulation of epithelial cell differentiation GO:0030857 2 0.028
specification of symmetry GO:0009799 204 0.027
medial fin development GO:0033338 16 0.027
posterior lateral line development GO:0048916 38 0.027
Zebrafish
cellular protein localization GO:0034613 20 0.027
Zebrafish
regulation of glial cell differentiation GO:0045685 4 0.027
Mouse
determination of left right symmetry GO:0007368 179 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.027
negative regulation of myeloid cell differentiation GO:0045638 1 0.027
regulation of positive chemotaxis GO:0050926 4 0.026
Zebrafish
post embryonic foregut morphogenesis GO:0048618 3 0.026
endodermal cell fate specification GO:0001714 17 0.026
positive regulation of neuron migration GO:2001224 2 0.026
neuromast development GO:0048884 46 0.026
protein complex localization GO:0031503 1 0.026
reproductive process GO:0022414 40 0.026
Zebrafish Mouse
smooth muscle tissue development GO:0048745 1 0.025
intracellular transport GO:0046907 32 0.025
Zebrafish
establishment of protein localization to plasma membrane GO:0090002 1 0.025
epiboly GO:0090504 41 0.025
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.025
germ line stem cell maintenance GO:0030718 2 0.025
gtp catabolic process GO:0006184 2 0.025
artery morphogenesis GO:0048844 14 0.025
establishment of cell polarity involved in mesendodermal cell migration GO:0003369 1 0.024
erk1 and erk2 cascade GO:0070371 4 0.024
mesoderm formation GO:0001707 43 0.024
blood circulation GO:0008015 87 0.024
Rat
negative regulation of protein kinase activity GO:0006469 4 0.024
ectoderm formation GO:0001705 2 0.024
meiotic chromosome segregation GO:0045132 3 0.023
regulation of organ morphogenesis GO:2000027 35 0.023

cxcr4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033