Danio rerio

4 known processes

cyp3a65

cytochrome P450, family 3, subfamily A, polypeptide 65

(Aliases: MGC123110,zgc:123110)

cyp3a65 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
maintenance of location GO:0051235 4 0.594
cellular biosynthetic process GO:0044249 286 0.569
Human Fly
cellular response to xenobiotic stimulus GO:0071466 35 0.559
Fly
small molecule metabolic process GO:0044281 77 0.413
Human Fly
single organism metabolic process GO:0044710 217 0.289
Human Mouse Rat Fly
lipid storage GO:0019915 1 0.285
cellular response to chemical stimulus GO:0070887 157 0.258
Fly
cellular hormone metabolic process GO:0034754 19 0.237
Fly
positive regulation of defense response GO:0031349 9 0.218
heterocycle metabolic process GO:0046483 290 0.213
Human
response to xenobiotic stimulus GO:0009410 45 0.184
response to organic substance GO:0010033 153 0.169
Rat Fly
regulation of metabolic process GO:0019222 359 0.167
Mouse
regulation of transcription dna templated GO:0006355 213 0.164
blood vessel morphogenesis GO:0048514 216 0.161
nitrogen compound metabolic process GO:0006807 319 0.158
Human
regulation of biological quality GO:0065008 263 0.158
Fly
lipid catabolic process GO:0016042 4 0.155
Human
response to stress GO:0006950 263 0.154
Fly
regulation of protein localization to nucleus GO:1900180 2 0.149
regulation of cellular biosynthetic process GO:0031326 245 0.148
endothelial cell development GO:0001885 12 0.146
regulation of nitrogen compound metabolic process GO:0051171 251 0.145
response to chemical GO:0042221 320 0.145
organic substance biosynthetic process GO:1901576 289 0.137
Human Fly
positive regulation of cytokine production GO:0001819 2 0.134
nucleic acid metabolic process GO:0090304 244 0.133
cellular nitrogen compound metabolic process GO:0034641 290 0.131
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.131
biosynthetic process GO:0009058 294 0.129
Human Fly
segment polarity determination GO:0007367 1 0.123
cellular macromolecule metabolic process GO:0044260 391 0.122
endothelial cell differentiation GO:0045446 20 0.121
organic cyclic compound biosynthetic process GO:1901362 223 0.117
Human Fly
monovalent inorganic cation transport GO:0015672 42 0.112
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.111
response to transition metal nanoparticle GO:1990267 28 0.110
Fly
organism emergence from protective structure GO:0071684 4 0.106
response to organic cyclic compound GO:0014070 51 0.102
Rat Fly
organic cyclic compound metabolic process GO:1901360 301 0.098
Human Fly
single organism transport GO:0044765 206 0.098
regulation of biosynthetic process GO:0009889 250 0.092
epithelial cell differentiation GO:0030855 116 0.091
regulation of primary metabolic process GO:0080090 311 0.085
secondary metabolic process GO:0019748 3 0.084
Fly
nucleic acid templated transcription GO:0097659 181 0.083
regulation of rna metabolic process GO:0051252 224 0.083
regulation of gene expression GO:0010468 265 0.083
Mouse
heterocycle biosynthetic process GO:0018130 215 0.079
protein localization to nucleus GO:0034504 3 0.079
positive regulation of transport GO:0051050 2 0.078
cellular response to estrogen stimulus GO:0071391 24 0.076
cell motility GO:0048870 244 0.076
cellular amine metabolic process GO:0044106 2 0.075
response to amine GO:0014075 1 0.071
positive regulation of immune system process GO:0002684 17 0.071
regulation of macromolecule biosynthetic process GO:0010556 225 0.070
epithelial cell development GO:0002064 42 0.069
circadian sleep wake cycle GO:0042745 2 0.068
cellular aromatic compound metabolic process GO:0006725 295 0.068
endothelium development GO:0003158 25 0.068
single organism localization GO:1902578 225 0.068
aging GO:0007568 2 0.067
Rat
nucleobase containing compound metabolic process GO:0006139 274 0.065
system process GO:0003008 185 0.064
Fly
sensory system development GO:0048880 76 0.063
small molecule catabolic process GO:0044282 3 0.063
nucleobase containing compound biosynthetic process GO:0034654 205 0.063
signal transduction GO:0007165 455 0.060
rna biosynthetic process GO:0032774 181 0.059
response to hexose GO:0009746 3 0.059
steroid metabolic process GO:0008202 7 0.058
Human Fly
lateral line system development GO:0048925 76 0.057
gene expression GO:0010467 252 0.057
Mouse
organic acid metabolic process GO:0006082 31 0.056
Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.055
response to alkaloid GO:0043279 2 0.053
Fly
positive regulation of cell activation GO:0050867 1 0.053
response to alcohol GO:0097305 14 0.052
defense response GO:0006952 47 0.050
Fly
negative regulation of blood circulation GO:1903523 2 0.050
organelle organization GO:0006996 227 0.049
wound healing GO:0042060 90 0.048
sensory organ development GO:0007423 393 0.048
response to drug GO:0042493 3 0.048
Human Rat
regulation of innate immune response GO:0045088 11 0.047
cellular response to organic substance GO:0071310 105 0.046
regulation of fatty acid metabolic process GO:0019217 1 0.046
regulation of blood pressure GO:0008217 1 0.046
response to wounding GO:0009611 116 0.046
regulation of tube size GO:0035150 2 0.044
growth GO:0040007 174 0.044
Fly
periodic partitioning GO:0007365 1 0.043
oxidation reduction process GO:0055114 41 0.043
Human Mouse Rat Fly
aromatic compound biosynthetic process GO:0019438 217 0.043
cellular nitrogen compound biosynthetic process GO:0044271 218 0.043
amine metabolic process GO:0009308 2 0.042
regulation of metal ion transport GO:0010959 4 0.042
regulation of rna biosynthetic process GO:2001141 213 0.042
regulation of inflammatory response GO:0050727 2 0.042
response to endogenous stimulus GO:0009719 83 0.042
Rat Fly
response to metal ion GO:0010038 34 0.041
Rat Fly
regulation of protein import into nucleus GO:0042306 2 0.041
adult behavior GO:0030534 2 0.041
cell killing GO:0001906 2 0.041
positive regulation of cellular catabolic process GO:0031331 3 0.040
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.040
caudal fin development GO:0033336 9 0.039
locomotion GO:0040011 313 0.038
cellular ketone metabolic process GO:0042180 11 0.038
Fly
homeostatic process GO:0042592 142 0.037
protein import into nucleus GO:0006606 3 0.037
lateral line development GO:0048882 66 0.037
lipid metabolic process GO:0006629 52 0.037
Human Fly
negative regulation of cellular process GO:0048523 283 0.036
vasculature development GO:0001944 278 0.036
regulation of cell activation GO:0050865 1 0.035
response to lipid GO:0033993 60 0.034
Rat
neuromast development GO:0048884 46 0.034
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.033
transcription dna templated GO:0006351 181 0.033
regulation of establishment of protein localization GO:0070201 4 0.033
hormone metabolic process GO:0042445 19 0.033
Fly
hemopoiesis GO:0030097 183 0.033
positive regulation of response to stimulus GO:0048584 80 0.033
xenobiotic metabolic process GO:0006805 4 0.033
Fly
endocardial cushion morphogenesis GO:0003203 3 0.033
cellular lipid metabolic process GO:0044255 36 0.033
Human Fly
digestive tract development GO:0048565 265 0.033
oxoacid metabolic process GO:0043436 31 0.033
Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.032
response to carbohydrate GO:0009743 3 0.032
lymphatic endothelial cell fate commitment GO:0060838 1 0.032
smooth muscle contraction GO:0006939 2 0.031
hormone transport GO:0009914 2 0.031
cellular biogenic amine metabolic process GO:0006576 2 0.031
fin development GO:0033333 77 0.030
regulation of sodium ion transport GO:0002028 2 0.030
regionalization GO:0003002 274 0.029
cellular response to external stimulus GO:0071496 2 0.029
macromolecule localization GO:0033036 54 0.029
hatching GO:0035188 4 0.029
regulation of cellular ph GO:0030641 1 0.029
digestive system process GO:0022600 9 0.029
cell surface receptor signaling pathway GO:0007166 325 0.029
multicellular organism growth GO:0035264 4 0.028
lipid homeostasis GO:0055088 3 0.028
response to vitamin GO:0033273 3 0.028
macromolecule biosynthetic process GO:0009059 227 0.028
negative regulation of biological process GO:0048519 304 0.027
response to monosaccharide GO:0034284 3 0.027
neuron neuron synaptic transmission GO:0007270 1 0.027
protein acetylation GO:0006473 2 0.027
peptide transport GO:0015833 1 0.027
establishment of localization GO:0051234 244 0.026
i kappab kinase nf kappab signaling GO:0007249 4 0.026
response to steroid hormone GO:0048545 35 0.026
Rat
developmental growth GO:0048589 166 0.026
Fly
positive regulation of secretion GO:0051047 1 0.026
regulation of localization GO:0032879 104 0.026
response to inorganic substance GO:0010035 38 0.025
Rat Fly
nucleocytoplasmic transport GO:0006913 4 0.025
positive regulation of cellular process GO:0048522 201 0.025
digestive tract morphogenesis GO:0048546 231 0.025
regulation of immune response GO:0050776 14 0.025
response to oxygen containing compound GO:1901700 55 0.025
post embryonic morphogenesis GO:0009886 4 0.025
regulation of cellular metabolic process GO:0031323 320 0.025
hormone secretion GO:0046879 2 0.025
nuclear transport GO:0051169 4 0.024
regulation of hormone levels GO:0010817 21 0.024
Fly
organic substance catabolic process GO:1901575 28 0.024
Human
organic cyclic compound catabolic process GO:1901361 15 0.024
Human
chemical homeostasis GO:0048878 49 0.024
rna metabolic process GO:0016070 219 0.024
response to abiotic stimulus GO:0009628 122 0.023
Fly
response to amphetamine GO:0001975 1 0.023
foregut morphogenesis GO:0007440 4 0.023
larval development GO:0002164 2 0.023
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.023
angiogenesis GO:0001525 158 0.023
retinoid metabolic process GO:0001523 15 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
negative regulation of metabolic process GO:0009892 86 0.023
cellular response to estradiol stimulus GO:0071392 1 0.022
ovulation cycle process GO:0022602 2 0.022
single organism biosynthetic process GO:0044711 71 0.022
Human Fly
blood vessel development GO:0001568 246 0.022
multi organism process GO:0051704 134 0.022
Fly
medial fin development GO:0033338 16 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.021
regulation of molecular function GO:0065009 70 0.021
protein targeting to nucleus GO:0044744 3 0.021
embryo development ending in birth or egg hatching GO:0009792 271 0.021
negative regulation of macromolecule metabolic process GO:0010605 76 0.021
regulation of nucleocytoplasmic transport GO:0046822 2 0.020
regulation of cell communication GO:0010646 232 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
negative regulation of heart contraction GO:0045822 2 0.020
ion transmembrane transport GO:0034220 91 0.020
cellular lipid catabolic process GO:0044242 3 0.020
negative regulation of transcription dna templated GO:0045892 45 0.020
single fertilization GO:0007338 3 0.019
negative regulation of cellular metabolic process GO:0031324 77 0.019
mononuclear cell proliferation GO:0032943 1 0.019
cellular response to endogenous stimulus GO:0071495 68 0.019
regulation of hormone secretion GO:0046883 2 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
regulation of protein transport GO:0051223 3 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
Human
regulation of macromolecule metabolic process GO:0060255 317 0.019
Mouse
response to glucose GO:0009749 3 0.019
meiotic nuclear division GO:0007126 4 0.019
nuclear import GO:0051170 3 0.019
fertilization GO:0009566 3 0.019
sodium ion homeostasis GO:0055078 3 0.019
cell death GO:0008219 121 0.019
regulation of calcium ion transport GO:0051924 2 0.018
cellular response to starvation GO:0009267 1 0.018
protein import GO:0017038 3 0.018
single organism nuclear import GO:1902593 3 0.018
regulation of establishment of planar polarity GO:0090175 4 0.018
cellular response to organic cyclic compound GO:0071407 38 0.018
regulation of multicellular organismal process GO:0051239 277 0.018
ion transport GO:0006811 114 0.018
immune system development GO:0002520 191 0.018
polyol metabolic process GO:0019751 1 0.017
Human
modification dependent macromolecule catabolic process GO:0043632 3 0.017
negative regulation of rna metabolic process GO:0051253 48 0.017
establishment of endothelial barrier GO:0061028 3 0.017
protein secretion GO:0009306 1 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.017
androgen metabolic process GO:0008209 2 0.017
cell migration GO:0016477 237 0.017
regulation of blood vessel size GO:0050880 2 0.016
epidermis development GO:0008544 48 0.016
ovulation cycle GO:0042698 2 0.016
regulation of immune system process GO:0002682 34 0.016
acylglycerol homeostasis GO:0055090 2 0.016
generation of neurons GO:0048699 385 0.016
reactive oxygen species biosynthetic process GO:1903409 1 0.016
fin regeneration GO:0031101 51 0.016
alcohol metabolic process GO:0006066 11 0.016
Human Fly
negative regulation of gene expression GO:0010629 65 0.015
regulation of signaling GO:0023051 235 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
regulation of protein targeting GO:1903533 2 0.015
monovalent inorganic cation homeostasis GO:0055067 9 0.015
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.015
cell proliferation GO:0008283 80 0.015
intracellular receptor signaling pathway GO:0030522 30 0.015
inorganic cation transmembrane transport GO:0098662 50 0.015
regulation of sequestering of calcium ion GO:0051282 4 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
lipid oxidation GO:0034440 1 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
catecholamine metabolic process GO:0006584 2 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
positive regulation of inflammatory response GO:0050729 1 0.015
regulation of signal transduction GO:0009966 225 0.014
positive regulation of leukocyte mediated immunity GO:0002705 1 0.014
protein metabolic process GO:0019538 183 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
blood circulation GO:0008015 87 0.014
localization of cell GO:0051674 244 0.014
immune system process GO:0002376 241 0.014
retinoic acid receptor signaling pathway GO:0048384 16 0.014
organic substance transport GO:0071702 58 0.014
carboxylic acid catabolic process GO:0046395 3 0.014
gtp catabolic process GO:0006184 2 0.013
digestive system development GO:0055123 289 0.013
sensory perception of pain GO:0019233 1 0.013
negative regulation of cellular protein metabolic process GO:0032269 16 0.013
nitric oxide biosynthetic process GO:0006809 2 0.013
embryonic hemopoiesis GO:0035162 53 0.013
cellular localization GO:0051641 97 0.013
negative regulation of rna biosynthetic process GO:1902679 45 0.013
gastrulation GO:0007369 208 0.013
circulatory system process GO:0003013 87 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
post embryonic foregut morphogenesis GO:0048618 3 0.013
negative regulation of secretion by cell GO:1903531 2 0.013
mitochondrion organization GO:0007005 4 0.013
anion transport GO:0006820 38 0.013
cellular response to lipid GO:0071396 39 0.012
single organism catabolic process GO:0044712 13 0.012
Human Fly
regulation of muscle contraction GO:0006937 3 0.012
bmp signaling pathway GO:0030509 52 0.012
regeneration GO:0031099 91 0.012
intracellular estrogen receptor signaling pathway GO:0030520 3 0.012
response to ketone GO:1901654 1 0.012
regulation of transporter activity GO:0032409 2 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.012
apical junction assembly GO:0043297 1 0.012
embryonic organ development GO:0048568 381 0.012
embryonic digestive tract morphogenesis GO:0048557 3 0.012
collagen fibril organization GO:0030199 1 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
phototransduction GO:0007602 2 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
response to other organism GO:0051707 97 0.012
Fly
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
regulation of programmed cell death GO:0043067 101 0.012
medial fin morphogenesis GO:0035141 14 0.011
negative regulation of feeding behavior GO:2000252 2 0.011
metal ion transport GO:0030001 58 0.011
intracellular signal transduction GO:0035556 85 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
Fly
transmembrane transport GO:0055085 120 0.011
immune response GO:0006955 28 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
stem cell division GO:0017145 1 0.011
response to hormone GO:0009725 48 0.011
Rat
tissue regeneration GO:0042246 74 0.011
regulation of cytokine production GO:0001817 3 0.011
regulation of response to stimulus GO:0048583 269 0.011
muscle cell development GO:0055001 115 0.011
sequestering of calcium ion GO:0051208 3 0.011
urogenital system development GO:0001655 97 0.011
zymogen activation GO:0031638 3 0.011
gland development GO:0048732 143 0.011
fat soluble vitamin metabolic process GO:0006775 4 0.011
Human
regulation of systemic arterial blood pressure GO:0003073 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
anterior commissure morphogenesis GO:0021960 3 0.010
response to nicotine GO:0035094 2 0.010
regulation of cardiac muscle contraction GO:0055117 2 0.010
positive regulation of cellular biosynthetic process GO:0031328 68 0.010
regulation of intracellular signal transduction GO:1902531 57 0.010
epiboly GO:0090504 41 0.010
response to nutrient levels GO:0031667 10 0.010
Rat
membrane invagination GO:0010324 1 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
dopamine metabolic process GO:0042417 2 0.010
regulation of protein catabolic process GO:0042176 1 0.010
cellular response to radiation GO:0071478 4 0.010

cyp3a65 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.062
Human
myopathy DOID:423 0 0.043
muscular disease DOID:0080000 0 0.043
heart disease DOID:114 0 0.043
cardiomyopathy DOID:0050700 0 0.043
intrinsic cardiomyopathy DOID:0060036 0 0.043
cardiovascular system disease DOID:1287 0 0.043
Human
musculoskeletal system disease DOID:17 0 0.043
muscle tissue disease DOID:66 0 0.043
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.019
nervous system disease DOID:863 0 0.018
disease of mental health DOID:150 0 0.013
developmental disorder of mental health DOID:0060037 0 0.013