Danio rerio

72 known processes

dazl

daz-like gene

dazl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pole plasm assembly GO:0007315 4 0.954
oocyte construction GO:0007308 5 0.699
regulation of nucleic acid templated transcription GO:1903506 213 0.563
segmentation GO:0035282 97 0.508
oocyte anterior posterior axis specification GO:0007314 4 0.506
maternal determination of anterior posterior axis embryo GO:0008358 4 0.478
negative regulation of cellular process GO:0048523 283 0.424
meiotic nuclear division GO:0007126 4 0.423
Mouse
gene expression GO:0010467 252 0.419
axis specification GO:0009798 43 0.417
regulation of transcription dna templated GO:0006355 213 0.417
dorsal ventral pattern formation GO:0009953 125 0.401
macromolecule biosynthetic process GO:0009059 227 0.383
cytoplasm organization GO:0007028 4 0.358
regionalization GO:0003002 274 0.334
oocyte maturation GO:0001556 4 0.330
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.316
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.301
Mouse
oocyte axis specification GO:0007309 5 0.283
organic cyclic compound metabolic process GO:1901360 301 0.279
nucleic acid metabolic process GO:0090304 244 0.275
rna localization GO:0006403 4 0.259
regulation of mrna processing GO:0050684 3 0.254
meiosis ii GO:0007135 1 0.246
Mouse
regulation of rna metabolic process GO:0051252 224 0.244
regulation of mrna catabolic process GO:0061013 3 0.239
positive regulation of biological process GO:0048518 253 0.235
cell cycle process GO:0022402 53 0.225
Mouse
embryonic axis specification GO:0000578 12 0.219
regulation of metabolic process GO:0019222 359 0.217
cell surface receptor signaling pathway GO:0007166 325 0.217
regulation of localization GO:0032879 104 0.209
regulation of multicellular organismal development GO:2000026 223 0.208
dna alkylation GO:0006305 8 0.207
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.185
anterior posterior axis specification GO:0009948 20 0.181
female gamete generation GO:0007292 14 0.179
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.179
organic cyclic compound biosynthetic process GO:1901362 223 0.168
mitotic cell cycle GO:0000278 64 0.167
chromosome organization involved in meiosis GO:0070192 1 0.160
locomotion GO:0040011 313 0.156
mesoderm development GO:0007498 88 0.149
spermatid development GO:0007286 2 0.146
meiotic chromosome segregation GO:0045132 3 0.136
negative regulation of biological process GO:0048519 304 0.134
developmental maturation GO:0021700 34 0.133
Mouse
establishment of localization in cell GO:0051649 77 0.132
male meiosis GO:0007140 2 0.126
organelle organization GO:0006996 227 0.123
Mouse
oocyte differentiation GO:0009994 14 0.120
Mouse
multicellular organism reproduction GO:0032504 35 0.119
Mouse
multi organism process GO:0051704 134 0.119
Mouse
dsrna fragmentation GO:0031050 1 0.116
regulation of multicellular organismal process GO:0051239 277 0.114
cellular macromolecule biosynthetic process GO:0034645 224 0.113
regulation of gene expression GO:0010468 265 0.108
xenobiotic metabolic process GO:0006805 4 0.103
oogenesis GO:0048477 14 0.103
Mouse
heart looping GO:0001947 94 0.100
cellular component assembly GO:0022607 170 0.098
nitrogen compound metabolic process GO:0006807 319 0.098
oocyte development GO:0048599 14 0.096
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.095
regulation of cellular metabolic process GO:0031323 320 0.095
cellular component biogenesis GO:0044085 178 0.095
anterior posterior pattern specification GO:0009952 152 0.095
determination of dorsal ventral asymmetry GO:0048262 34 0.094
positive regulation of cellular metabolic process GO:0031325 94 0.093
smad protein complex assembly GO:0007183 1 0.092
biosynthetic process GO:0009058 294 0.092
tripartite regional subdivision GO:0007351 5 0.091
growth GO:0040007 174 0.090
organelle fission GO:0048285 23 0.089
Mouse
immune system process GO:0002376 241 0.088
regulation of developmental process GO:0050793 247 0.088
regulation of cellular biosynthetic process GO:0031326 245 0.085
positive regulation of gene expression GO:0010628 71 0.083
response to chemical GO:0042221 320 0.081
heterocycle metabolic process GO:0046483 290 0.080
rna biosynthetic process GO:0032774 181 0.078
apoptotic process GO:0006915 116 0.075
mitotic nuclear division GO:0007067 18 0.074
bicarbonate transport GO:0015701 4 0.072
morphogenesis of an epithelium GO:0002009 333 0.072
regulation of primary metabolic process GO:0080090 311 0.072
cellular localization GO:0051641 97 0.069
digestive tract morphogenesis GO:0048546 231 0.069
germ cell migration GO:0008354 8 0.067
organic substance biosynthetic process GO:1901576 289 0.067
positive regulation of cellular process GO:0048522 201 0.065
neuron projection development GO:0031175 180 0.065
regulation of cytokine production GO:0001817 3 0.064
determination of left right symmetry GO:0007368 179 0.064
nuclear division GO:0000280 23 0.063
Mouse
regulation of cell communication GO:0010646 232 0.063
cell cycle GO:0007049 93 0.062
Mouse
single organism organelle organization GO:1902589 199 0.062
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.060
signal transduction GO:0007165 455 0.060
aromatic compound biosynthetic process GO:0019438 217 0.060
nucleic acid templated transcription GO:0097659 181 0.059
positive regulation of macromolecule metabolic process GO:0010604 93 0.058
regulation of protein complex assembly GO:0043254 3 0.058
cell motility GO:0048870 244 0.057
cellular biosynthetic process GO:0044249 286 0.057
single organism localization GO:1902578 225 0.057
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.056
regulation of response to stimulus GO:0048583 269 0.055
cellular component movement GO:0006928 335 0.055
oocyte growth GO:0001555 1 0.055
spemann organizer formation GO:0060061 10 0.055
sexual reproduction GO:0019953 36 0.054
Mouse
regulation of locomotion GO:0040012 55 0.054
multicellular organismal reproductive process GO:0048609 35 0.054
Mouse
bmp signaling pathway GO:0030509 52 0.054
tube morphogenesis GO:0035239 349 0.053
regulation of mrna metabolic process GO:1903311 6 0.053
anterior posterior axis specification embryo GO:0008595 5 0.053
generation of neurons GO:0048699 385 0.053
germ cell development GO:0007281 22 0.052
Mouse
single organism reproductive process GO:0044702 40 0.052
Mouse
gastrulation GO:0007369 208 0.051
hepaticobiliary system development GO:0061008 98 0.050
regulation of cell development GO:0060284 100 0.050
single organism metabolic process GO:0044710 217 0.050
embryonic pattern specification GO:0009880 44 0.049
spermatid differentiation GO:0048515 2 0.049
specification of organ identity GO:0010092 2 0.049
determination of bilateral symmetry GO:0009855 204 0.049
notochord development GO:0030903 54 0.047
cell part morphogenesis GO:0032990 246 0.047
female meiotic division GO:0007143 2 0.046
Mouse
neuron development GO:0048666 262 0.046
regulation of wnt signaling pathway GO:0030111 53 0.046
positive regulation of developmental process GO:0051094 50 0.046
regulation of oocyte development GO:0060281 3 0.046
larval development GO:0002164 2 0.046
alternative mrna splicing via spliceosome GO:0000380 1 0.045
female meiosis chromosome segregation GO:0016321 1 0.045
cellular component morphogenesis GO:0032989 336 0.045
dorsal ventral axis specification GO:0009950 14 0.045
mitotic sister chromatid segregation GO:0000070 6 0.044
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.044
regulation of cell maturation GO:1903429 1 0.043
cellular nitrogen compound biosynthetic process GO:0044271 218 0.043
aging GO:0007568 2 0.043
nucleobase containing compound biosynthetic process GO:0034654 205 0.043
axial mesodermal cell fate specification GO:0048327 3 0.042
regulation of biosynthetic process GO:0009889 250 0.042
multi organism reproductive process GO:0044703 36 0.041
Mouse
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.041
rna 3 end processing GO:0031123 2 0.041
astral microtubule organization GO:0030953 1 0.040
maintenance of location GO:0051235 4 0.040
regulation of signal transduction GO:0009966 225 0.040
muscle organ development GO:0007517 101 0.039
response to dexamethasone GO:0071548 1 0.039
cellular aromatic compound metabolic process GO:0006725 295 0.038
regulation of rna biosynthetic process GO:2001141 213 0.038
er to golgi vesicle mediated transport GO:0006888 1 0.038
gamete generation GO:0007276 33 0.037
Mouse
liver development GO:0001889 96 0.037
cellular nitrogen compound metabolic process GO:0034641 290 0.037
germ line stem cell maintenance GO:0030718 2 0.036
neuron differentiation GO:0030182 353 0.035
single organism transport GO:0044765 206 0.035
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.035
meiosis i GO:0007127 1 0.035
cell maturation GO:0048469 23 0.034
Mouse
rna metabolic process GO:0016070 219 0.034
developmental cell growth GO:0048588 52 0.034
programmed cell death GO:0012501 119 0.034
regulation of cell differentiation GO:0045595 142 0.034
canonical wnt signaling pathway GO:0060070 48 0.034
heterocycle biosynthetic process GO:0018130 215 0.033
negative regulation of signal transduction GO:0009968 94 0.033
response to external stimulus GO:0009605 264 0.033
regulation of signaling GO:0023051 235 0.033
transcription dna templated GO:0006351 181 0.032
regulation of macromolecule biosynthetic process GO:0010556 225 0.032
wnt signaling pathway GO:0016055 80 0.032
negative regulation of cell communication GO:0010648 96 0.032
neuron projection extension GO:1990138 45 0.032
cell death GO:0008219 121 0.032
reproductive process GO:0022414 40 0.032
Mouse
innate immune response GO:0045087 13 0.031
response to stress GO:0006950 263 0.031
positive regulation of catabolic process GO:0009896 4 0.031
reproduction GO:0000003 40 0.030
Mouse Worm
dna methylation GO:0006306 8 0.030
positive regulation of transport GO:0051050 2 0.030
positive regulation of nucleic acid templated transcription GO:1903508 57 0.029
microtubule based process GO:0007017 60 0.029
convergent extension involved in gastrulation GO:0060027 71 0.029
female meiosis ii GO:0007147 1 0.029
Mouse
determination of dorsal identity GO:0048263 13 0.029
stem cell division GO:0017145 1 0.029
mitotic cell cycle process GO:1903047 48 0.029
mrna splicing via spliceosome GO:0000398 10 0.029
digestive system development GO:0055123 289 0.028
chromosome organization GO:0051276 31 0.028
meiotic cell cycle process GO:1903046 3 0.028
Mouse
mrna 3 end processing GO:0031124 2 0.028
macromolecular complex subunit organization GO:0043933 74 0.028
regulation of reproductive process GO:2000241 4 0.028
macromolecule localization GO:0033036 54 0.028
negative regulation of signaling GO:0023057 96 0.028
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.027
development of primary female sexual characteristics GO:0046545 4 0.027
spemann organizer formation at the embryonic shield GO:0060063 2 0.027
regulation of chromosome segregation GO:0051983 1 0.027
embryonic limb morphogenesis GO:0030326 2 0.027
chromosome segregation GO:0007059 12 0.026
regulation of response to cytokine stimulus GO:0060759 3 0.026
positive regulation of map kinase activity GO:0043406 3 0.026
heart morphogenesis GO:0003007 156 0.026
single fertilization GO:0007338 3 0.026
cell projection organization GO:0030030 284 0.026
rna catabolic process GO:0006401 7 0.025
embryonic organ development GO:0048568 381 0.024
female sex differentiation GO:0046660 4 0.024
developmental process involved in reproduction GO:0003006 27 0.024
Mouse
skeletal muscle organ development GO:0060538 78 0.024
positive regulation of muscle organ development GO:0048636 1 0.024
intracellular mrna localization GO:0008298 1 0.024
cell projection morphogenesis GO:0048858 244 0.024
regulation of biological quality GO:0065008 263 0.024
cell migration GO:0016477 237 0.024
dicarboxylic acid metabolic process GO:0043648 1 0.024
regulation of cell cycle GO:0051726 52 0.023
Mouse
cellular response to estradiol stimulus GO:0071392 1 0.023
positive regulation of cellular biosynthetic process GO:0031328 68 0.023
regulation of cellular component movement GO:0051270 55 0.023
negative regulation of dna replication GO:0008156 2 0.023
death GO:0016265 121 0.022
stem cell proliferation GO:0072089 4 0.022
female germ line stem cell maintenance GO:0036099 1 0.022
angiogenesis GO:0001525 158 0.022
cell morphogenesis GO:0000902 289 0.022
localization of cell GO:0051674 244 0.022
embryonic heart tube morphogenesis GO:0003143 108 0.022
liver morphogenesis GO:0072576 8 0.021
endoderm development GO:0007492 49 0.021
cellular response to organic substance GO:0071310 105 0.021
specification of organ position GO:0010159 3 0.021
axonogenesis GO:0007409 152 0.021
synapsis GO:0007129 1 0.021
cellular response to oxygen levels GO:0071453 1 0.021
golgi vesicle transport GO:0048193 3 0.021
sensory perception of chemical stimulus GO:0007606 3 0.021
negative regulation of ras protein signal transduction GO:0046580 1 0.021
vasculature development GO:0001944 278 0.021
developmental growth GO:0048589 166 0.021
axon guidance GO:0007411 86 0.021
establishment of localization GO:0051234 244 0.020
Worm
cell aging GO:0007569 2 0.020
germ line stem cell division GO:0042078 1 0.020
regulation of inflammatory response GO:0050727 2 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
cell morphogenesis involved in differentiation GO:0000904 195 0.020
developmental growth involved in morphogenesis GO:0060560 86 0.020
formation of primary germ layer GO:0001704 62 0.019
embryonic heart tube development GO:0035050 133 0.019
chromatin organization GO:0006325 22 0.019
cellular protein metabolic process GO:0044267 129 0.019
regulation of anatomical structure morphogenesis GO:0022603 130 0.019
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.019
positive regulation of translation GO:0045727 1 0.019
dna modification GO:0006304 8 0.019
stem cell maintenance GO:0019827 4 0.019
camera type eye development GO:0043010 222 0.019
calcium ion import GO:0070509 4 0.019
positive regulation of response to stimulus GO:0048584 80 0.018
endodermal cell differentiation GO:0035987 19 0.018
specification of symmetry GO:0009799 204 0.018
blood vessel development GO:0001568 246 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
embryonic digestive tract development GO:0048566 4 0.018
negative regulation of macromolecule metabolic process GO:0010605 76 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
embryonic organ morphogenesis GO:0048562 274 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.017
muscle structure development GO:0061061 196 0.017
regulation of dna recombination GO:0000018 2 0.017
hemopoiesis GO:0030097 183 0.017
regulation of cell aging GO:0090342 1 0.017
cell proliferation GO:0008283 80 0.017
endoderm formation GO:0001706 29 0.016
mrna metabolic process GO:0016071 20 0.016
regulation of gene expression epigenetic GO:0040029 11 0.016
chemotaxis GO:0006935 104 0.016
regulation of neurogenesis GO:0050767 87 0.016
positive regulation of mrna metabolic process GO:1903313 2 0.016
skeletal system development GO:0001501 181 0.016
regulation of phosphorus metabolic process GO:0051174 43 0.016
cellular response to hypoxia GO:0071456 1 0.016
embryonic digestive tract morphogenesis GO:0048557 3 0.015
mesoderm formation GO:0001707 43 0.015
phosphorus metabolic process GO:0006793 109 0.015
negative regulation of cellular metabolic process GO:0031324 77 0.015
regulation of circadian rhythm GO:0042752 4 0.015
axial mesoderm formation GO:0048320 4 0.015
rna polyadenylation GO:0043631 2 0.015
immune response GO:0006955 28 0.015
sister chromatid segregation GO:0000819 6 0.015
rna processing GO:0006396 25 0.015
nuclear transcribed mrna catabolic process GO:0000956 4 0.015
cellular response to starvation GO:0009267 1 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.015
regulation of apoptotic process GO:0042981 98 0.015
single organism biosynthetic process GO:0044711 71 0.015
negative regulation of dna metabolic process GO:0051053 4 0.014
defense response to other organism GO:0098542 33 0.014
regulation of programmed cell death GO:0043067 101 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
negative regulation of multicellular organismal process GO:0051241 69 0.014
regulation of organelle organization GO:0033043 29 0.014
Mouse
proximal distal pattern formation GO:0009954 1 0.014
response to xenobiotic stimulus GO:0009410 45 0.014
peptide transport GO:0015833 1 0.014
regulation of phospholipase c activity GO:1900274 1 0.014
odontogenesis of dentin containing tooth GO:0042475 1 0.014
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.014
regulation of cell death GO:0010941 103 0.014
regulation of protein transport GO:0051223 3 0.014
regulation of embryonic development GO:0045995 47 0.014
prechordal plate formation GO:0021501 3 0.014
mesodermal cell fate commitment GO:0001710 14 0.014
positive regulation of metabolic process GO:0009893 108 0.014
axon development GO:0061564 166 0.014
somitogenesis GO:0001756 87 0.014
activation of mapk activity GO:0000187 3 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
positive regulation of lipase activity GO:0060193 1 0.013
dna metabolic process GO:0006259 27 0.013
dna biosynthetic process GO:0071897 3 0.013
regulation of cell growth GO:0001558 29 0.013
negative regulation of gene expression GO:0010629 65 0.013
single organism cellular localization GO:1902580 46 0.013
regulation of mrna splicing via spliceosome GO:0048024 3 0.013
morphogenesis of follicular epithelium GO:0016333 1 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
negative regulation of embryonic development GO:0045992 11 0.013
rna stabilization GO:0043489 4 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
heart field specification GO:0003128 1 0.013
cell division GO:0051301 20 0.013
Mouse
regulation of canonical wnt signaling pathway GO:0060828 34 0.013
spliceosomal snrnp assembly GO:0000387 2 0.012
cell migration involved in gastrulation GO:0042074 79 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
positive regulation of biosynthetic process GO:0009891 68 0.012
multicellular organism growth GO:0035264 4 0.012
behavior GO:0007610 74 0.012
female gonad development GO:0008585 4 0.012
methylation GO:0032259 22 0.012
cell growth GO:0016049 57 0.012
negative regulation of response to stimulus GO:0048585 104 0.011
establishment of organelle localization GO:0051656 45 0.011
sister chromatid cohesion GO:0007062 2 0.011
muscle cell development GO:0055001 115 0.011
regulation of rna splicing GO:0043484 8 0.011
regulation of dna metabolic process GO:0051052 11 0.011
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.011
transport GO:0006810 220 0.011
Worm
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.011
cellular response to xenobiotic stimulus GO:0071466 35 0.011
heart development GO:0007507 313 0.011
negative regulation of multi organism process GO:0043901 3 0.011
cytokinesis GO:0000910 3 0.011
phagocytosis GO:0006909 3 0.011
protein complex subunit organization GO:0071822 46 0.011
meiotic spindle organization GO:0000212 1 0.011
negative regulation of mitosis GO:0045839 3 0.011
striated muscle cell development GO:0055002 108 0.010
catabolic process GO:0009056 32 0.010
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.010
blood vessel morphogenesis GO:0048514 216 0.010
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.010
regulation of protein metabolic process GO:0051246 56 0.010
establishment of endothelial barrier GO:0061028 3 0.010
regulation of cell activation GO:0050865 1 0.010
cellular response to external stimulus GO:0071496 2 0.010
protein metabolic process GO:0019538 183 0.010
interspecies interaction between organisms GO:0044419 4 0.010

dazl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.038
disease of anatomical entity DOID:7 0 0.038
eye and adnexa disease DOID:1492 0 0.038
nervous system disease DOID:863 0 0.038
eye disease DOID:5614 0 0.038
disease of metabolism DOID:0014667 0 0.017
retinal disease DOID:5679 0 0.015
retinal degeneration DOID:8466 0 0.015