Danio rerio

14 known processes

dcaf7

ddb1 and cul4 associated factor 7

(Aliases: wu:fj83g06,wdr68,han11l,zgc:63940,fj83g06)

dcaf7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleobase containing compound metabolic process GO:0006139 274 0.882
Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.556
Worm
regulation of gene expression GO:0010468 265 0.555
neuron development GO:0048666 262 0.541
Worm
nitrogen compound metabolic process GO:0006807 319 0.490
Worm
larval development GO:0002164 2 0.452
cellular macromolecule metabolic process GO:0044260 391 0.409
macromolecule biosynthetic process GO:0009059 227 0.394
heterocycle metabolic process GO:0046483 290 0.374
Worm
regulation of developmental process GO:0050793 247 0.372
Worm
gene expression GO:0010467 252 0.361
cell motility GO:0048870 244 0.346
Worm
eye development GO:0001654 277 0.334
protein metabolic process GO:0019538 183 0.318
transcription dna templated GO:0006351 181 0.302
negative regulation of biological process GO:0048519 304 0.298
Worm
regulation of metabolic process GO:0019222 359 0.297
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.294
Worm
cellular component movement GO:0006928 335 0.283
Worm
cell morphogenesis GO:0000902 289 0.275
Worm
organic cyclic compound metabolic process GO:1901360 301 0.275
Worm
organic substance biosynthetic process GO:1901576 289 0.273
gland development GO:0048732 143 0.266
neuron differentiation GO:0030182 353 0.260
Worm
nucleic acid metabolic process GO:0090304 244 0.258
regulation of nucleic acid templated transcription GO:1903506 213 0.256
cellular macromolecule biosynthetic process GO:0034645 224 0.255
rna biosynthetic process GO:0032774 181 0.254
regulation of cellular metabolic process GO:0031323 320 0.248
Worm
cellular aromatic compound metabolic process GO:0006725 295 0.246
Worm
regulation of macromolecule metabolic process GO:0060255 317 0.245
regulation of cellular biosynthetic process GO:0031326 245 0.245
positive regulation of biological process GO:0048518 253 0.237
Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.234
regulation of primary metabolic process GO:0080090 311 0.226
Worm
regulation of transcription dna templated GO:0006355 213 0.213
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.211
skeletal system development GO:0001501 181 0.194
hematopoietic or lymphoid organ development GO:0048534 191 0.182
cellular biosynthetic process GO:0044249 286 0.181
cellular nitrogen compound biosynthetic process GO:0044271 218 0.180
cell projection organization GO:0030030 284 0.179
Worm
embryonic organ morphogenesis GO:0048562 274 0.179
heart development GO:0007507 313 0.177
regulation of biosynthetic process GO:0009889 250 0.176
aromatic compound biosynthetic process GO:0019438 217 0.174
single organism organelle organization GO:1902589 199 0.173
regionalization GO:0003002 274 0.166
cellular component biogenesis GO:0044085 178 0.160
negative regulation of cellular process GO:0048523 283 0.159
Worm
regulation of multicellular organismal development GO:2000026 223 0.156
Worm
cellular component assembly GO:0022607 170 0.156
chordate embryonic development GO:0043009 271 0.149
generation of neurons GO:0048699 385 0.148
Worm
hemopoiesis GO:0030097 183 0.142
regulation of rna metabolic process GO:0051252 224 0.138
biosynthetic process GO:0009058 294 0.135
regulation of response to stimulus GO:0048583 269 0.134
Worm Fly
muscle structure development GO:0061061 196 0.134
Fly
regulation of multicellular organismal process GO:0051239 277 0.129
Worm
single organism localization GO:1902578 225 0.128
Worm
rna metabolic process GO:0016070 219 0.128
response to stress GO:0006950 263 0.127
morphogenesis of an epithelium GO:0002009 333 0.124
nucleic acid templated transcription GO:0097659 181 0.124
embryo development ending in birth or egg hatching GO:0009792 271 0.122
central nervous system development GO:0007417 387 0.122
single organism transport GO:0044765 206 0.121
Worm
embryonic skeletal system morphogenesis GO:0048704 93 0.115
negative regulation of metabolic process GO:0009892 86 0.112
cell surface receptor signaling pathway GO:0007166 325 0.111
protein acetylation GO:0006473 2 0.109
regulation of macromolecule biosynthetic process GO:0010556 225 0.108
regulation of rna biosynthetic process GO:2001141 213 0.106
sensory organ development GO:0007423 393 0.104
regulation of nitrogen compound metabolic process GO:0051171 251 0.104
Worm
organic cyclic compound biosynthetic process GO:1901362 223 0.099
establishment of localization GO:0051234 244 0.098
Worm
camera type eye development GO:0043010 222 0.092
positive regulation of metabolic process GO:0009893 108 0.088
axonogenesis GO:0007409 152 0.086
Worm
positive regulation of transport GO:0051050 2 0.084
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.083
connective tissue development GO:0061448 99 0.083
single organism metabolic process GO:0044710 217 0.081
Worm
cellular protein catabolic process GO:0044257 4 0.081
anterior posterior pattern specification GO:0009952 152 0.080
cell migration GO:0016477 237 0.079
Worm
somite development GO:0061053 96 0.079
locomotion GO:0040011 313 0.079
Worm
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.077
localization of cell GO:0051674 244 0.077
Worm
striated muscle tissue development GO:0014706 110 0.077
heterocycle biosynthetic process GO:0018130 215 0.077
negative regulation of cell communication GO:0010648 96 0.076
stem cell differentiation GO:0048863 117 0.076
muscle organ development GO:0007517 101 0.075
Fly
signal transduction GO:0007165 455 0.073
Fly
organelle assembly GO:0070925 110 0.071
stem cell maintenance GO:0019827 4 0.069
regulation of signal transduction GO:0009966 225 0.068
Worm Fly
nuclear transport GO:0051169 4 0.068
regulation of nervous system development GO:0051960 90 0.067
Worm
immune system development GO:0002520 191 0.067
cartilage development GO:0051216 96 0.063
programmed cell death GO:0012501 119 0.062
immune system process GO:0002376 241 0.060
retina development in camera type eye GO:0060041 146 0.060
embryonic organ development GO:0048568 381 0.058
cellular component morphogenesis GO:0032989 336 0.058
Worm
cellular protein metabolic process GO:0044267 129 0.058
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.058
Worm
endodermal cell fate determination GO:0007493 2 0.057
organonitrogen compound metabolic process GO:1901564 74 0.056
Worm
protein acylation GO:0043543 3 0.056
liver development GO:0001889 96 0.055
cell morphogenesis involved in differentiation GO:0000904 195 0.054
Worm
positive regulation of neuron apoptotic process GO:0043525 1 0.053
neuron projection morphogenesis GO:0048812 161 0.052
Worm
adult behavior GO:0030534 2 0.052
protein import into nucleus GO:0006606 3 0.051
regulation of stem cell differentiation GO:2000736 4 0.051
determination of left right symmetry GO:0007368 179 0.051
response to chemical GO:0042221 320 0.050
regulation of embryonic development GO:0045995 47 0.050
cell cycle GO:0007049 93 0.049
cell cycle process GO:0022402 53 0.049
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.048
nuclear import GO:0051170 3 0.048
positive regulation of cellular biosynthetic process GO:0031328 68 0.048
small molecule metabolic process GO:0044281 77 0.047
Worm
apoptotic process GO:0006915 116 0.046
proteoglycan metabolic process GO:0006029 14 0.046
organelle organization GO:0006996 227 0.045
reproduction GO:0000003 40 0.045
oxoacid metabolic process GO:0043436 31 0.045
regulation of production of molecular mediator of immune response GO:0002700 1 0.044
regulation of cell differentiation GO:0045595 142 0.044
Worm
positive regulation of cellular process GO:0048522 201 0.043
Fly
regulation of gene expression epigenetic GO:0040029 11 0.042
modification dependent macromolecule catabolic process GO:0043632 3 0.041
regulation of protein targeting GO:1903533 2 0.041
cellular amine metabolic process GO:0044106 2 0.041
response to organic substance GO:0010033 153 0.040
stem cell development GO:0048864 82 0.040
gastrulation GO:0007369 208 0.040
cardiac cell development GO:0055006 21 0.040
macromolecular complex subunit organization GO:0043933 74 0.039
tube morphogenesis GO:0035239 349 0.039
mitotic cell cycle GO:0000278 64 0.039
head development GO:0060322 303 0.039
production of molecular mediator of immune response GO:0002440 2 0.038
establishment of protein localization to organelle GO:0072594 4 0.038
digestive tract development GO:0048565 265 0.038
single organism nuclear import GO:1902593 3 0.038
positive regulation of secretion GO:0051047 1 0.037
digestive tract morphogenesis GO:0048546 231 0.037
dorsal ventral pattern formation GO:0009953 125 0.037
positive regulation of cellular metabolic process GO:0031325 94 0.036
positive regulation of biosynthetic process GO:0009891 68 0.036
blood vessel development GO:0001568 246 0.036
cardiocyte differentiation GO:0035051 44 0.035
cellular response to chemical stimulus GO:0070887 157 0.035
death GO:0016265 121 0.034
peptidyl lysine acetylation GO:0018394 2 0.034
embryonic cranial skeleton morphogenesis GO:0048701 90 0.034
regulation of cell death GO:0010941 103 0.034
convergent extension GO:0060026 118 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.033
cell part morphogenesis GO:0032990 246 0.033
Worm
regulation of anatomical structure morphogenesis GO:0022603 130 0.033
Worm
cellular protein modification process GO:0006464 100 0.032
cardiac muscle tissue development GO:0048738 48 0.032
regulation of protein transport GO:0051223 3 0.032
regulation of cellular ketone metabolic process GO:0010565 7 0.031
ubiquitin dependent protein catabolic process GO:0006511 3 0.031
axon development GO:0061564 166 0.031
Worm
regulation of molecular function GO:0065009 70 0.031
Worm
reproductive process GO:0022414 40 0.031
digestive system development GO:0055123 289 0.031
regulation of neural precursor cell proliferation GO:2000177 3 0.031
macromolecule modification GO:0043412 111 0.031
positive regulation of catabolic process GO:0009896 4 0.031
brain development GO:0007420 293 0.030
alternative mrna splicing via spliceosome GO:0000380 1 0.030
determination of bilateral symmetry GO:0009855 204 0.030
organic acid metabolic process GO:0006082 31 0.030
multi organism process GO:0051704 134 0.030
establishment of localization in cell GO:0051649 77 0.029
regulation of establishment of protein localization GO:0070201 4 0.029
cell proliferation GO:0008283 80 0.029
regulation of transport GO:0051049 45 0.029
Worm
regulation of myelination GO:0031641 1 0.029
regulation of cell activation GO:0050865 1 0.029
protein targeting to nucleus GO:0044744 3 0.029
specification of symmetry GO:0009799 204 0.028
camera type eye morphogenesis GO:0048593 108 0.028
protein import GO:0017038 3 0.028
internal peptidyl lysine acetylation GO:0018393 2 0.028
protein localization to nucleus GO:0034504 3 0.028
regulation of signaling GO:0023051 235 0.028
Worm Fly
regulation of reproductive process GO:2000241 4 0.027
spinal cord development GO:0021510 46 0.027
maintenance of location GO:0051235 4 0.027
positive regulation of synapse assembly GO:0051965 1 0.027
aorta development GO:0035904 4 0.026
regulation of cellular component organization GO:0051128 86 0.026
Worm
regulation of protein catabolic process GO:0042176 1 0.026
cellular ketone metabolic process GO:0042180 11 0.025
embryonic skeletal system development GO:0048706 97 0.025
regulation of localization GO:0032879 104 0.025
Worm
heart morphogenesis GO:0003007 156 0.025
regulation of protein import into nucleus GO:0042306 2 0.025
regulation of nucleocytoplasmic transport GO:0046822 2 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
cytokinesis GO:0000910 3 0.025
positive regulation of apoptotic signaling pathway GO:2001235 1 0.025
response to abiotic stimulus GO:0009628 122 0.025
neural tube patterning GO:0021532 33 0.024
behavior GO:0007610 74 0.024
positive regulation of rna biosynthetic process GO:1902680 57 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
negative regulation of cellular biosynthetic process GO:0031327 55 0.024
muscle tissue development GO:0060537 110 0.024
striated muscle cell development GO:0055002 108 0.024
growth GO:0040007 174 0.024
Worm Fly
cognition GO:0050890 1 0.024
exocytosis GO:0006887 1 0.023
negative regulation of transcription dna templated GO:0045892 45 0.023
gene silencing GO:0016458 4 0.023
regulation of protein ubiquitination GO:0031396 3 0.023
germ line stem cell maintenance GO:0030718 2 0.023
regulation of epithelial cell proliferation GO:0050678 3 0.023
enzyme linked receptor protein signaling pathway GO:0007167 106 0.022
appendage development GO:0048736 80 0.022
mesenchymal cell differentiation GO:0048762 87 0.022
regulation of cell development GO:0060284 100 0.022
Worm
homeostatic process GO:0042592 142 0.022
protein secretion GO:0009306 1 0.022
response to wounding GO:0009611 116 0.022
positive regulation of rna metabolic process GO:0051254 59 0.022
transcription from rna polymerase ii promoter GO:0006366 80 0.022
regulation of mrna processing GO:0050684 3 0.022
regulation of cell shape GO:0008360 1 0.021
multicellular organism growth GO:0035264 4 0.021
skeletal system morphogenesis GO:0048705 102 0.021
forebrain development GO:0030900 96 0.020
positive regulation of stem cell proliferation GO:2000648 1 0.020
stem cell division GO:0017145 1 0.020
cellular response to organic substance GO:0071310 105 0.020
aging GO:0007568 2 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
vasculature development GO:0001944 278 0.020
epithelial cell differentiation GO:0030855 116 0.020
lipid storage GO:0019915 1 0.020
intracellular signal transduction GO:0035556 85 0.020
Fly
transport GO:0006810 220 0.019
Worm
cytoskeleton dependent cytokinesis GO:0061640 3 0.019
synaptic growth at neuromuscular junction GO:0051124 2 0.019
carbohydrate derivative metabolic process GO:1901135 61 0.019
Worm
cell fate commitment GO:0045165 99 0.019
negative regulation of signaling GO:0023057 96 0.019
regulation of tube size GO:0035150 2 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
regulation of apoptotic process GO:0042981 98 0.019
cell projection morphogenesis GO:0048858 244 0.019
Worm
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.019
pancreas development GO:0031016 84 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
blood vessel morphogenesis GO:0048514 216 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
regeneration GO:0031099 91 0.018
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.018
positive regulation of transcription dna templated GO:0045893 57 0.018
muscle cell differentiation GO:0042692 139 0.018
pigment cell differentiation GO:0050931 38 0.018
polarized epithelial cell differentiation GO:0030859 4 0.017
specification of organ identity GO:0010092 2 0.017
regulation of cytokine production GO:0001817 3 0.017
developmental pigmentation GO:0048066 48 0.017
proximal distal pattern formation GO:0009954 1 0.017
cellular localization GO:0051641 97 0.017
catabolic process GO:0009056 32 0.017
Worm
neuron migration GO:0001764 22 0.017
modification dependent protein catabolic process GO:0019941 3 0.016
organic substance transport GO:0071702 58 0.016
embryonic heart tube development GO:0035050 133 0.016
regulation of programmed cell death GO:0043067 101 0.016
mesenchymal cell proliferation GO:0010463 1 0.016
negative regulation of gene expression GO:0010629 65 0.016
neuron projection development GO:0031175 180 0.016
Worm
golgi vesicle transport GO:0048193 3 0.016
hindbrain development GO:0030902 91 0.016
cytokinetic process GO:0032506 2 0.016
segmentation GO:0035282 97 0.016
compound eye development GO:0048749 2 0.016
proteolysis GO:0006508 38 0.016
cell death GO:0008219 121 0.016
formation of primary germ layer GO:0001704 62 0.016
developmental growth GO:0048589 166 0.016
Worm
circadian sleep wake cycle process GO:0022410 2 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.015
negative regulation of multicellular organismal process GO:0051241 69 0.015
regulation of developmental growth GO:0048638 38 0.015
Worm
forebrain anterior posterior pattern specification GO:0021797 3 0.015
regulation of synapse organization GO:0050807 3 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
central nervous system neuron differentiation GO:0021953 74 0.015
regulation of binding GO:0051098 3 0.015
response to biotic stimulus GO:0009607 97 0.015
negative regulation of apoptotic process GO:0043066 55 0.015
cilium morphogenesis GO:0060271 85 0.015
negative regulation of biosynthetic process GO:0009890 55 0.014
internal protein amino acid acetylation GO:0006475 2 0.014
regulation of establishment of planar polarity GO:0090175 4 0.014
anterior head development GO:0097065 2 0.014
ameboidal type cell migration GO:0001667 143 0.014
actin filament based movement GO:0030048 1 0.014
forebrain cell migration GO:0021885 1 0.014
cellular component assembly involved in morphogenesis GO:0010927 107 0.014
recombinational repair GO:0000725 1 0.014
rostrocaudal neural tube patterning GO:0021903 29 0.014
midbrain hindbrain boundary development GO:0030917 23 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
Worm
epithelial cell morphogenesis involved in gastrulation GO:0003381 1 0.014
cell proliferation involved in heart morphogenesis GO:0061323 2 0.014
mesenchyme development GO:0060485 127 0.014
cytoskeleton organization GO:0007010 96 0.014
myeloid cell differentiation GO:0030099 86 0.013
autophagy GO:0006914 4 0.013
rna processing GO:0006396 25 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
regulation of cell proliferation GO:0042127 37 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
endocrine system development GO:0035270 65 0.013
system process GO:0003008 185 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
regulation of phosphorus metabolic process GO:0051174 43 0.013
Worm
negative regulation of protein transport GO:0051224 3 0.013
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
convergent extension involved in gastrulation GO:0060027 71 0.013
negative regulation of defense response GO:0031348 2 0.013
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.013
mesoderm development GO:0007498 88 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
regulation of microtubule cytoskeleton organization GO:0070507 3 0.013
mitotic cell cycle process GO:1903047 48 0.013
retina morphogenesis in camera type eye GO:0060042 79 0.013
fertilization GO:0009566 3 0.013
protein modification by small protein conjugation GO:0032446 13 0.013
somitogenesis GO:0001756 87 0.012
embryonic viscerocranium morphogenesis GO:0048703 52 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
glycosaminoglycan biosynthetic process GO:0006024 8 0.012
negative regulation of axon regeneration GO:0048681 4 0.012
rna modification GO:0009451 2 0.012
gtp catabolic process GO:0006184 2 0.012
Worm
cellular response to stress GO:0033554 62 0.012
phosphorus metabolic process GO:0006793 109 0.012
Worm
circadian sleep wake cycle sleep GO:0050802 1 0.012
regulation of cell communication GO:0010646 232 0.012
Worm Fly
rna 3 end processing GO:0031123 2 0.012
odontogenesis of dentin containing tooth GO:0042475 1 0.012
heart looping GO:0001947 94 0.012
body morphogenesis GO:0010171 16 0.012
sister chromatid cohesion GO:0007062 2 0.012
sensory neuron axon guidance GO:0097374 3 0.012
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.012
positive regulation of nucleic acid templated transcription GO:1903508 57 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
response to oxygen containing compound GO:1901700 55 0.011
cellular response to starvation GO:0009267 1 0.011
macromolecule localization GO:0033036 54 0.011
regulation of neuron differentiation GO:0045664 56 0.011
Worm
regulation of inflammatory response GO:0050727 2 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
protein localization GO:0008104 40 0.011
larval behavior GO:0030537 5 0.011
fin development GO:0033333 77 0.011
positive regulation of notch signaling pathway GO:0045747 3 0.011
photoreceptor cell maintenance GO:0045494 11 0.011
neuroblast proliferation GO:0007405 2 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
dna templated transcription elongation GO:0006354 3 0.011
wnt signaling pathway GO:0016055 80 0.011
regulation of mesenchymal cell proliferation GO:0010464 1 0.011
hepaticobiliary system development GO:0061008 98 0.011
somatic cell dna recombination GO:0016444 1 0.011
gene silencing by rna GO:0031047 4 0.011
positive regulation of gene expression GO:0010628 71 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
neuroepithelial cell differentiation GO:0060563 26 0.010
response to lipid GO:0033993 60 0.010
microtubule cytoskeleton organization GO:0000226 33 0.010
somatic stem cell maintenance GO:0035019 1 0.010
b cell activation GO:0042113 2 0.010
embryonic heart tube morphogenesis GO:0003143 108 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.010
cellular response to external stimulus GO:0071496 2 0.010
regulation of synapse assembly GO:0051963 3 0.010
regulation of myotube differentiation GO:0010830 2 0.010
tissue homeostasis GO:0001894 25 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.010
cellular amino acid metabolic process GO:0006520 7 0.010
developmental growth involved in morphogenesis GO:0060560 86 0.010
Worm

dcaf7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.032
cancer DOID:162 0 0.025
organ system cancer DOID:0050686 0 0.022
intestinal cancer DOID:10155 0 0.012
gastrointestinal system cancer DOID:3119 0 0.012
large intestine cancer DOID:5672 0 0.012