Danio rerio

0 known processes

dera

2-deoxyribose-5-phosphate aldolase homolog (C. elegans)

(Aliases: zgc:101610)

dera biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism nuclear import GO:1902593 3 0.117
establishment of protein localization to organelle GO:0072594 4 0.106
oxidation reduction process GO:0055114 41 0.095
cellular macromolecule metabolic process GO:0044260 391 0.090
regulation of synaptic plasticity GO:0048167 1 0.089
carboxylic acid catabolic process GO:0046395 3 0.083
catechol containing compound metabolic process GO:0009712 2 0.080
nuclear transport GO:0051169 4 0.071
positive regulation of transport GO:0051050 2 0.069
maintenance of location GO:0051235 4 0.068
protein targeting to nucleus GO:0044744 3 0.067
digestive system development GO:0055123 289 0.066
protein import into nucleus GO:0006606 3 0.064
nucleocytoplasmic transport GO:0006913 4 0.063
regulation of gene expression GO:0010468 265 0.062
organic substance biosynthetic process GO:1901576 289 0.060
nuclear import GO:0051170 3 0.056
aging GO:0007568 2 0.055
cellular amino acid biosynthetic process GO:0008652 2 0.055
secondary metabolic process GO:0019748 3 0.054
positive regulation of secretion by cell GO:1903532 1 0.054
alpha amino acid metabolic process GO:1901605 3 0.052
regulation of cell communication GO:0010646 232 0.052
regulation of reactive oxygen species metabolic process GO:2000377 2 0.052
leukocyte proliferation GO:0070661 1 0.049
regulation of transcription dna templated GO:0006355 213 0.048
positive regulation of secretion GO:0051047 1 0.048
nucleobase containing compound biosynthetic process GO:0034654 205 0.047
macromolecule biosynthetic process GO:0009059 227 0.047
protein import GO:0017038 3 0.046
cellular macromolecule biosynthetic process GO:0034645 224 0.046
heterocycle metabolic process GO:0046483 290 0.045
organic acid metabolic process GO:0006082 31 0.045
regulation of cytokine production GO:0001817 3 0.045
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.045
organic cyclic compound metabolic process GO:1901360 301 0.045
cellular amino acid metabolic process GO:0006520 7 0.044
aromatic compound biosynthetic process GO:0019438 217 0.043
organic acid catabolic process GO:0016054 3 0.043
catecholamine metabolic process GO:0006584 2 0.043
nitrogen compound metabolic process GO:0006807 319 0.043
dopamine metabolic process GO:0042417 2 0.042
lipid storage GO:0019915 1 0.042
gene expression GO:0010467 252 0.041
oxoacid metabolic process GO:0043436 31 0.041
phagocytosis GO:0006909 3 0.041
autophagy GO:0006914 4 0.040
cellular nitrogen compound metabolic process GO:0034641 290 0.039
response to stress GO:0006950 263 0.039
carboxylic acid metabolic process GO:0019752 22 0.038
protein localization to nucleus GO:0034504 3 0.038
cellular nitrogen compound biosynthetic process GO:0044271 218 0.038
locomotion GO:0040011 313 0.038
negative regulation of biological process GO:0048519 304 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.037
rna metabolic process GO:0016070 219 0.036
regulation of metabolic process GO:0019222 359 0.035
cellular response to lipopolysaccharide GO:0071222 3 0.035
response to uv GO:0009411 3 0.035
biosynthetic process GO:0009058 294 0.034
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.033
regulation of protein transport GO:0051223 3 0.033
regulation of primary metabolic process GO:0080090 311 0.033
mitochondrion organization GO:0007005 4 0.033
regulation of developmental process GO:0050793 247 0.033
cellular amine metabolic process GO:0044106 2 0.033
heterocycle biosynthetic process GO:0018130 215 0.032
signal transduction GO:0007165 455 0.032
regulation of nitrogen compound metabolic process GO:0051171 251 0.032
programmed cell death GO:0012501 119 0.032
nucleic acid templated transcription GO:0097659 181 0.031
glucose import GO:0046323 2 0.031
lymphocyte proliferation GO:0046651 1 0.031
single organism metabolic process GO:0044710 217 0.031
monoamine transport GO:0015844 1 0.031
cellular aromatic compound metabolic process GO:0006725 295 0.031
organonitrogen compound biosynthetic process GO:1901566 47 0.031
regulation of cytoplasmic transport GO:1903649 4 0.030
regulation of macromolecule biosynthetic process GO:0010556 225 0.030
regulation of programmed cell death GO:0043067 101 0.030
response to drug GO:0042493 3 0.030
dopamine biosynthetic process GO:0042416 2 0.030
regulation of signaling GO:0023051 235 0.029
cofactor metabolic process GO:0051186 15 0.028
catechol containing compound biosynthetic process GO:0009713 2 0.028
regulation of cell activation GO:0050865 1 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
cellular amide metabolic process GO:0043603 4 0.028
multicellular organism growth GO:0035264 4 0.027
rna biosynthetic process GO:0032774 181 0.027
death GO:0016265 121 0.027
positive regulation of cell activation GO:0050867 1 0.027
regulation of macromolecule metabolic process GO:0060255 317 0.027
peptide metabolic process GO:0006518 1 0.027
immune system process GO:0002376 241 0.027
regulation of signal transduction GO:0009966 225 0.026
amine metabolic process GO:0009308 2 0.026
hemopoiesis GO:0030097 183 0.026
regulation of inflammatory response GO:0050727 2 0.026
regulation of intracellular protein transport GO:0033157 3 0.026
mononuclear cell proliferation GO:0032943 1 0.026
regulation of response to stimulus GO:0048583 269 0.026
larval development GO:0002164 2 0.025
cellular protein catabolic process GO:0044257 4 0.025
response to hydrogen peroxide GO:0042542 3 0.025
response to nutrient GO:0007584 3 0.025
regulation of stem cell proliferation GO:0072091 2 0.025
regulation of hormone secretion GO:0046883 2 0.024
small molecule metabolic process GO:0044281 77 0.024
negative regulation of kinase activity GO:0033673 4 0.024
gtp metabolic process GO:0046039 4 0.024
positive regulation of cellular catabolic process GO:0031331 3 0.024
regulation of biological quality GO:0065008 263 0.024
regulation of autophagy GO:0010506 3 0.023
cellular catabolic process GO:0044248 27 0.023
blood circulation GO:0008015 87 0.023
regulation of multicellular organismal process GO:0051239 277 0.023
regulation of nucleic acid templated transcription GO:1903506 213 0.023
mitotic dna damage checkpoint GO:0044773 4 0.023
response to chemical GO:0042221 320 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.022
protein acetylation GO:0006473 2 0.022
erk1 and erk2 cascade GO:0070371 4 0.022
cellular biosynthetic process GO:0044249 286 0.022
response to external biotic stimulus GO:0043207 97 0.022
regulation of erk1 and erk2 cascade GO:0070372 4 0.022
cellular carbohydrate metabolic process GO:0044262 4 0.021
response to external stimulus GO:0009605 264 0.021
regulation of systemic arterial blood pressure GO:0003073 1 0.021
development of primary female sexual characteristics GO:0046545 4 0.021
cardiocyte differentiation GO:0035051 44 0.021
protein secretion GO:0009306 1 0.021
hematopoietic or lymphoid organ development GO:0048534 191 0.021
regulation of biosynthetic process GO:0009889 250 0.021
regulation of rna metabolic process GO:0051252 224 0.021
transcription dna templated GO:0006351 181 0.021
regulation of neuronal synaptic plasticity GO:0048168 1 0.021
pyruvate metabolic process GO:0006090 1 0.021
small molecule catabolic process GO:0044282 3 0.021
energy reserve metabolic process GO:0006112 2 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
regulation of protein localization to nucleus GO:1900180 2 0.021
positive regulation of catabolic process GO:0009896 4 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
negative regulation of catabolic process GO:0009895 3 0.021
response to alkaloid GO:0043279 2 0.021
protein localization to plasma membrane GO:0072659 1 0.020
adult behavior GO:0030534 2 0.020
regulation of transmembrane transporter activity GO:0022898 2 0.020
regulation of tube size GO:0035150 2 0.020
response to metal ion GO:0010038 34 0.020
regulation of cellular metabolic process GO:0031323 320 0.020
catecholamine biosynthetic process GO:0042423 2 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
cellular ketone metabolic process GO:0042180 11 0.020
response to monosaccharide GO:0034284 3 0.020
cellular response to external stimulus GO:0071496 2 0.020
reactive oxygen species metabolic process GO:0072593 6 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
neuron differentiation GO:0030182 353 0.020
cellular component morphogenesis GO:0032989 336 0.020
stem cell proliferation GO:0072089 4 0.020
hormone transport GO:0009914 2 0.020
regulation of jun kinase activity GO:0043506 3 0.020
response to biotic stimulus GO:0009607 97 0.019
lipid oxidation GO:0034440 1 0.019
cell death GO:0008219 121 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.019
regulation of blood pressure GO:0008217 1 0.019
negative regulation of protein kinase activity GO:0006469 4 0.019
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
negative regulation of cellular process GO:0048523 283 0.019
antimicrobial humoral response GO:0019730 2 0.019
meiotic nuclear division GO:0007126 4 0.019
cellular lipid catabolic process GO:0044242 3 0.019
apoptotic process GO:0006915 116 0.019
regulation of carbohydrate metabolic process GO:0006109 4 0.019
regulation of neural precursor cell proliferation GO:2000177 3 0.019
glucose homeostasis GO:0042593 1 0.019
spermatid differentiation GO:0048515 2 0.019
central nervous system development GO:0007417 387 0.019
gtp catabolic process GO:0006184 2 0.019
positive regulation of cellular process GO:0048522 201 0.018
response to abiotic stimulus GO:0009628 122 0.018
circadian sleep wake cycle GO:0042745 2 0.018
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
multi organism process GO:0051704 134 0.018
regulation of dna templated transcription in response to stress GO:0043620 0 0.018
regulation of apoptotic process GO:0042981 98 0.018
regulation of blood vessel size GO:0050880 2 0.018
positive regulation of leukocyte mediated immunity GO:0002705 1 0.018
spermatid development GO:0007286 2 0.018
response to oxygen radical GO:0000305 2 0.018
smooth muscle contraction GO:0006939 2 0.018
immune system development GO:0002520 191 0.018
zymogen activation GO:0031638 3 0.018
regulation of ph GO:0006885 3 0.018
superoxide metabolic process GO:0006801 2 0.018
establishment of localization in cell GO:0051649 77 0.018
neurotransmitter transport GO:0006836 2 0.018
female sex differentiation GO:0046660 4 0.018
negative regulation of cytokine production GO:0001818 1 0.018
response to wounding GO:0009611 116 0.017
organelle organization GO:0006996 227 0.017
somatic muscle development GO:0007525 4 0.017
cellular modified amino acid metabolic process GO:0006575 3 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
hydrogen peroxide metabolic process GO:0042743 2 0.017
cofactor biosynthetic process GO:0051188 10 0.017
regulation of cell death GO:0010941 103 0.017
internal peptidyl lysine acetylation GO:0018393 2 0.017
locomotor rhythm GO:0045475 3 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
transport GO:0006810 220 0.017
regulation of response to extracellular stimulus GO:0032104 1 0.017
primary amino compound biosynthetic process GO:1901162 1 0.016
cell aging GO:0007569 2 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
single organism localization GO:1902578 225 0.016
protein acylation GO:0043543 3 0.016
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.016
response to superoxide GO:0000303 2 0.016
tissue remodeling GO:0048771 4 0.016
regulation of dna replication GO:0006275 3 0.016
regulation of reproductive process GO:2000241 4 0.016
positive regulation of dna metabolic process GO:0051054 1 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
response to other organism GO:0051707 97 0.016
stem cell maintenance GO:0019827 4 0.016
regulation of metal ion transport GO:0010959 4 0.016
single organism organelle organization GO:1902589 199 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
carbohydrate homeostasis GO:0033500 1 0.015
cytokinesis GO:0000910 3 0.015
cellular component biogenesis GO:0044085 178 0.015
regulation of protein catabolic process GO:0042176 1 0.015
cellular response to organic substance GO:0071310 105 0.015
regulation of protein targeting GO:1903533 2 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
protein metabolic process GO:0019538 183 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
phenol containing compound biosynthetic process GO:0046189 4 0.015
indole containing compound metabolic process GO:0042430 2 0.015
activation of mapk activity GO:0000187 3 0.015
lipid catabolic process GO:0016042 4 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
nucleic acid metabolic process GO:0090304 244 0.015
positive regulation of cytokine production GO:0001819 2 0.015
dicarboxylic acid metabolic process GO:0043648 1 0.015
digestive tract morphogenesis GO:0048546 231 0.015
response to endogenous stimulus GO:0009719 83 0.014
positive regulation of leukocyte differentiation GO:1902107 1 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
long chain fatty acid metabolic process GO:0001676 1 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
regulation of transporter activity GO:0032409 2 0.014
response to hormone GO:0009725 48 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.014
internal protein amino acid acetylation GO:0006475 2 0.014
response to carbohydrate GO:0009743 3 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
regulation of gtpase activity GO:0043087 2 0.014
cell migration GO:0016477 237 0.014
cell cycle arrest GO:0007050 1 0.014
b cell differentiation GO:0030183 1 0.014
tube morphogenesis GO:0035239 349 0.014
cellular response to superoxide GO:0071451 2 0.014
membrane invagination GO:0010324 1 0.014
positive regulation of map kinase activity GO:0043406 3 0.014
regulation of sodium ion transport GO:0002028 2 0.014
toll like receptor signaling pathway GO:0002224 4 0.013
protein homooligomerization GO:0051260 3 0.013
response to amine GO:0014075 1 0.013
cell cell signaling GO:0007267 52 0.013
nucleic acid transport GO:0050657 2 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.013
pigmentation GO:0043473 85 0.013
response to amphetamine GO:0001975 1 0.013
regulation of cellular ph GO:0030641 1 0.013
negative regulation of programmed cell death GO:0043069 58 0.013
ovulation cycle process GO:0022602 2 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
b cell activation GO:0042113 2 0.013
response to organic substance GO:0010033 153 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
centrosome cycle GO:0007098 1 0.013
protein stabilization GO:0050821 2 0.013
system process GO:0003008 185 0.013
cell motility GO:0048870 244 0.013
response to glucocorticoid GO:0051384 1 0.013
cellular aldehyde metabolic process GO:0006081 4 0.013
cellular component assembly GO:0022607 170 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
peptide transport GO:0015833 1 0.013
cellular response to lipid GO:0071396 39 0.012
cytoskeleton organization GO:0007010 96 0.012
positive regulation of stem cell proliferation GO:2000648 1 0.012
negative regulation of apoptotic process GO:0043066 55 0.012
nuclear export GO:0051168 1 0.012
phagocytosis engulfment GO:0006911 1 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
female gonad development GO:0008585 4 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
positive regulation of myeloid cell differentiation GO:0045639 2 0.012
cell substrate junction assembly GO:0007044 2 0.012
response to unfolded protein GO:0006986 2 0.012
regulation of jak stat cascade GO:0046425 3 0.012
regulation of protein localization to plasma membrane GO:1903076 1 0.012
adherens junction organization GO:0034332 4 0.012
cell differentiation in spinal cord GO:0021515 40 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
synaptic vesicle transport GO:0048489 1 0.012
regulation of cell matrix adhesion GO:0001952 1 0.012
regulation of cell shape GO:0008360 1 0.012
hormone secretion GO:0046879 2 0.012
intracellular receptor signaling pathway GO:0030522 30 0.012
circulatory system process GO:0003013 87 0.012
hepaticobiliary system development GO:0061008 98 0.012
response to vitamin GO:0033273 3 0.012
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
cellular component disassembly GO:0022411 1 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
pigment metabolic process GO:0042440 12 0.012
regulation of circadian sleep wake cycle GO:0042749 1 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
leukocyte mediated cytotoxicity GO:0001909 1 0.012
cellular response to oxygen radical GO:0071450 2 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
meiotic cell cycle process GO:1903046 3 0.011
regulation of dna recombination GO:0000018 2 0.011
cellular response to oxygen levels GO:0071453 1 0.011
cellular response to nutrient levels GO:0031669 2 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
positive regulation of carbohydrate metabolic process GO:0045913 1 0.011
cell cell recognition GO:0009988 1 0.011
serotonin biosynthetic process GO:0042427 1 0.011
intra s dna damage checkpoint GO:0031573 1 0.011
regulation of production of molecular mediator of immune response GO:0002700 1 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
erythrocyte differentiation GO:0030218 54 0.011
alcohol biosynthetic process GO:0046165 2 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
cellular component movement GO:0006928 335 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
response to glucose GO:0009749 3 0.011
positive regulation of cell cycle GO:0045787 3 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.011
erythrocyte homeostasis GO:0034101 55 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
response to inorganic substance GO:0010035 38 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
digestive tract development GO:0048565 265 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
rna localization GO:0006403 4 0.011
synaptic vesicle localization GO:0097479 1 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
endosomal transport GO:0016197 2 0.011
localization of cell GO:0051674 244 0.011
muscle tissue development GO:0060537 110 0.010
cell projection morphogenesis GO:0048858 244 0.010
release of sequestered calcium ion into cytosol GO:0051209 3 0.010
positive regulation of inflammatory response GO:0050729 1 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
iron ion homeostasis GO:0055072 4 0.010
carboxylic acid biosynthetic process GO:0046394 12 0.010
microtubule organizing center organization GO:0031023 1 0.010
response to hexose GO:0009746 3 0.010
positive regulation of biological process GO:0048518 253 0.010
inositol lipid mediated signaling GO:0048017 2 0.010
negative regulation of sequestering of calcium ion GO:0051283 4 0.010
regulation of skeletal muscle tissue development GO:0048641 4 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
tyrosine phosphorylation of stat protein GO:0007260 1 0.010
establishment of localization GO:0051234 244 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
compound eye development GO:0048749 2 0.010
regulation of circadian rhythm GO:0042752 4 0.010
regulation of glucose transport GO:0010827 1 0.010
fatty acid oxidation GO:0019395 1 0.010
lateral inhibition GO:0046331 1 0.010
circadian sleep wake cycle sleep GO:0050802 1 0.010

dera disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.024
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
organ system cancer DOID:0050686 0 0.023
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.016
immune system disease DOID:2914 0 0.012
hematopoietic system disease DOID:74 0 0.012
musculoskeletal system disease DOID:17 0 0.011
inherited metabolic disorder DOID:655 0 0.011