|
|
spemann organizer formation
|
GO:0060061 |
10 |
0.986
|
|
|
|
diencephalon development
|
GO:0021536 |
58 |
0.983
|
|
|
|
head development
|
GO:0060322 |
303 |
0.945
|
Zebrafish |
|
|
notochord development
|
GO:0030903 |
54 |
0.939
|
|
|
|
notochord formation
|
GO:0014028 |
6 |
0.935
|
|
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.933
|
|
|
|
generation of neurons
|
GO:0048699 |
385 |
0.932
|
|
|
|
signal transduction
|
GO:0007165 |
455 |
0.930
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.930
|
|
|
|
determination of left right asymmetry in nervous system
|
GO:0035545 |
4 |
0.927
|
|
|
|
gall bladder development
|
GO:0061010 |
1 |
0.927
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
19 |
0.919
|
|
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.911
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
30 |
0.911
|
|
|
|
regionalization
|
GO:0003002 |
274 |
0.906
|
Zebrafish |
|
|
determination of left right asymmetry in diencephalon
|
GO:0035462 |
4 |
0.903
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
26 |
0.878
|
|
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.878
|
|
|
|
notochord morphogenesis
|
GO:0048570 |
17 |
0.877
|
|
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.875
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
56 |
0.864
|
|
|
|
response to chemical
|
GO:0042221 |
320 |
0.862
|
|
|
|
embryonic heart tube left right pattern formation
|
GO:0060971 |
5 |
0.859
|
|
|
|
regulation of developmental process
|
GO:0050793 |
247 |
0.846
|
|
|
|
digestive tract development
|
GO:0048565 |
265 |
0.838
|
|
|
|
locomotion
|
GO:0040011 |
313 |
0.811
|
|
|
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.810
|
Fly |
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
34 |
0.807
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.803
|
Worm |
|
|
limbic system development
|
GO:0021761 |
16 |
0.791
|
|
|
|
cell fate commitment
|
GO:0045165 |
99 |
0.789
|
|
|
|
axial mesoderm formation
|
GO:0048320 |
4 |
0.786
|
|
|
|
cellular component movement
|
GO:0006928 |
335 |
0.781
|
|
|
|
central nervous system development
|
GO:0007417 |
387 |
0.775
|
Zebrafish |
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.771
|
Fly |
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.766
|
|
|
|
gastrulation
|
GO:0007369 |
208 |
0.759
|
|
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.748
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
52 |
0.747
|
|
|
|
determination of dorsal identity
|
GO:0048263 |
13 |
0.742
|
|
|
|
digestive system development
|
GO:0055123 |
289 |
0.734
|
|
|
|
hepatic duct development
|
GO:0061011 |
2 |
0.731
|
|
|
|
hypothalamus development
|
GO:0021854 |
14 |
0.721
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
62 |
0.711
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
231 |
0.709
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
14 |
0.709
|
|
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.696
|
|
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.696
|
Fly |
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.691
|
|
|
|
bmp signaling pathway involved in determination of left right symmetry
|
GO:0003154 |
14 |
0.685
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
163 |
0.670
|
|
|
|
cell fate specification
|
GO:0001708 |
68 |
0.668
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.665
|
|
|
|
taxis
|
GO:0042330 |
109 |
0.660
|
|
|
|
brain development
|
GO:0007420 |
293 |
0.659
|
Zebrafish |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
80 |
0.653
|
|
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.647
|
Fly |
|
|
hepatocyte proliferation
|
GO:0072574 |
2 |
0.644
|
|
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.640
|
Fly |
|
|
dorsal ventral axis specification
|
GO:0009950 |
14 |
0.640
|
Zebrafish |
|
|
embryonic pattern specification
|
GO:0009880 |
44 |
0.637
|
|
|
|
cell surface receptor signaling pathway involved in heart development
|
GO:0061311 |
20 |
0.636
|
|
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.634
|
|
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.625
|
Fly |
|
|
eye morphogenesis
|
GO:0048592 |
144 |
0.605
|
|
|
|
regulation of endodermal cell fate specification
|
GO:0042663 |
15 |
0.602
|
|
|
|
forebrain development
|
GO:0030900 |
96 |
0.598
|
|
|
|
developmental induction
|
GO:0031128 |
10 |
0.598
|
|
|
|
negative regulation of anterior neural cell fate commitment of the neural plate
|
GO:0022001 |
1 |
0.587
|
|
|
|
embryonic camera type eye formation
|
GO:0060900 |
10 |
0.580
|
|
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.573
|
Fly |
|
|
regulation of cellular macromolecule biosynthetic process
|
GO:2000112 |
222 |
0.571
|
|
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.568
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.567
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
146 |
0.565
|
|
|
|
neuron development
|
GO:0048666 |
262 |
0.560
|
|
|
|
mesodermal cell fate specification
|
GO:0007501 |
12 |
0.544
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
152 |
0.543
|
Zebrafish |
|
|
chemotaxis
|
GO:0006935 |
104 |
0.540
|
|
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.540
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
50 |
0.537
|
|
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.536
|
|
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.533
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.533
|
|
|
|
neural tube development
|
GO:0021915 |
62 |
0.531
|
|
|
|
gastrulation with mouth forming second
|
GO:0001702 |
44 |
0.521
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
161 |
0.520
|
|
|
|
regulation of locomotion
|
GO:0040012 |
55 |
0.519
|
|
|
|
bmp signaling pathway involved in heart jogging
|
GO:0003303 |
14 |
0.518
|
|
|
|
response to endogenous stimulus
|
GO:0009719 |
83 |
0.518
|
|
|
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.516
|
Fly |
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.516
|
Fly |
|
|
optic placode formation involved in camera type eye formation
|
GO:0046619 |
3 |
0.511
|
|
|
|
eye development
|
GO:0001654 |
277 |
0.486
|
|
|
|
axon guidance
|
GO:0007411 |
86 |
0.479
|
|
|
|
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway
|
GO:0022002 |
1 |
0.476
|
|
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.474
|
|
|
|
larval development
|
GO:0002164 |
2 |
0.474
|
|
|
|
dorsal convergence
|
GO:0060030 |
14 |
0.472
|
|
|
|
camera type eye development
|
GO:0043010 |
222 |
0.470
|
|
|
|
sensory organ development
|
GO:0007423 |
393 |
0.466
|
|
|
|
metencephalon development
|
GO:0022037 |
27 |
0.454
|
|
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.448
|
Fly |
|
|
regulation of bmp signaling pathway involved in heart jogging
|
GO:2000223 |
12 |
0.446
|
|
|
|
positive regulation of fibroblast growth factor receptor signaling pathway
|
GO:0045743 |
9 |
0.439
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
17 |
0.430
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
125 |
0.427
|
Zebrafish |
|
|
cell migration
|
GO:0016477 |
237 |
0.423
|
|
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.418
|
|
|
|
embryonic neurocranium morphogenesis
|
GO:0048702 |
15 |
0.417
|
|
|
|
eye field cell fate commitment involved in camera type eye formation
|
GO:0060898 |
3 |
0.415
|
|
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.415
|
|
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.413
|
Fly |
|
|
axonogenesis
|
GO:0007409 |
152 |
0.407
|
|
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.391
|
Fly |
|
|
regeneration
|
GO:0031099 |
91 |
0.381
|
|
|
|
spinal cord anterior posterior patterning
|
GO:0021512 |
1 |
0.380
|
|
|
|
regulation of cell development
|
GO:0060284 |
100 |
0.379
|
|
|
|
cell projection organization
|
GO:0030030 |
284 |
0.377
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
96 |
0.377
|
|
|
|
ectodermal placode formation
|
GO:0060788 |
26 |
0.375
|
|
|
|
cellular localization
|
GO:0051641 |
97 |
0.369
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
133 |
0.368
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
29 |
0.368
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.365
|
|
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.363
|
|
|
|
axon development
|
GO:0061564 |
166 |
0.360
|
|
|
|
mesoderm development
|
GO:0007498 |
88 |
0.358
|
|
|
|
oogenesis
|
GO:0048477 |
14 |
0.348
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
39 |
0.348
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
35 |
0.348
|
|
|
|
mesoderm formation
|
GO:0001707 |
43 |
0.346
|
|
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.346
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.340
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
114 |
0.340
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
17 |
0.337
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
200 |
0.332
|
|
|
|
mediolateral intercalation
|
GO:0060031 |
3 |
0.331
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
37 |
0.330
|
|
|
|
cell motility
|
GO:0048870 |
244 |
0.329
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
130 |
0.327
|
|
|
|
regulation of cell fate specification
|
GO:0042659 |
20 |
0.325
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
48 |
0.322
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
35 |
0.318
|
|
|
|
homeostatic process
|
GO:0042592 |
142 |
0.316
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.316
|
|
|
|
neuron projection development
|
GO:0031175 |
180 |
0.311
|
|
|
|
mesodermal cell differentiation
|
GO:0048333 |
21 |
0.309
|
|
|
|
response to light stimulus
|
GO:0009416 |
46 |
0.308
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
56 |
0.307
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
106 |
0.305
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
80 |
0.293
|
Fly |
|
|
mesodermal cell migration
|
GO:0008078 |
12 |
0.293
|
|
|
|
floor plate morphogenesis
|
GO:0033505 |
12 |
0.291
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
35 |
0.288
|
|
|
|
regulation of cell fate commitment
|
GO:0010453 |
22 |
0.285
|
|
|
|
optic placode formation
|
GO:0001743 |
4 |
0.283
|
|
|
|
endodermal digestive tract morphogenesis
|
GO:0061031 |
2 |
0.282
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.278
|
|
|
|
muscle structure development
|
GO:0061061 |
196 |
0.277
|
|
|
|
oocyte maturation
|
GO:0001556 |
4 |
0.277
|
|
|
|
somitogenesis
|
GO:0001756 |
87 |
0.277
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
246 |
0.276
|
|
|
|
response to organic substance
|
GO:0010033 |
153 |
0.275
|
|
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.274
|
Fly |
|
|
sexual reproduction
|
GO:0019953 |
36 |
0.273
|
|
|
|
response to wounding
|
GO:0009611 |
116 |
0.268
|
|
|
|
behavior
|
GO:0007610 |
74 |
0.267
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.267
|
Fly |
|
|
liver development
|
GO:0001889 |
96 |
0.266
|
|
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.265
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
179 |
0.264
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
19 |
0.264
|
|
|
|
floor plate development
|
GO:0033504 |
15 |
0.264
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
56 |
0.260
|
|
|
|
establishment of localization
|
GO:0051234 |
244 |
0.260
|
|
|
|
regulation of wnt signaling pathway calcium modulating pathway
|
GO:0008591 |
3 |
0.257
|
|
|
|
heart morphogenesis
|
GO:0003007 |
156 |
0.256
|
|
|
|
circulatory system process
|
GO:0003013 |
87 |
0.253
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
51 |
0.252
|
|
|
|
anterior head development
|
GO:0097065 |
2 |
0.251
|
|
|
|
regulation of wnt signaling pathway involved in digestive tract morphogenesis
|
GO:2000056 |
2 |
0.250
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
12 |
0.250
|
|
|
|
regulation of anterior head development
|
GO:2000742 |
2 |
0.249
|
|
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.249
|
Fly |
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.249
|
|
|
|
regulation of cell size
|
GO:0008361 |
29 |
0.247
|
|
|
|
gland development
|
GO:0048732 |
143 |
0.246
|
|
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.243
|
Fly |
|
|
fin morphogenesis
|
GO:0033334 |
53 |
0.242
|
|
|
|
localization of cell
|
GO:0051674 |
244 |
0.241
|
|
|
|
neural tube patterning
|
GO:0021532 |
33 |
0.238
|
|
|
|
fin regeneration
|
GO:0031101 |
51 |
0.237
|
|
|
|
female gamete generation
|
GO:0007292 |
14 |
0.237
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
80 |
0.237
|
|
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
1 |
0.236
|
|
|
|
epithelial cell proliferation involved in liver morphogenesis
|
GO:0072575 |
2 |
0.233
|
|
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.229
|
Fly |
|
|
heart jogging
|
GO:0003146 |
40 |
0.229
|
|
|
|
negative regulation of oocyte development
|
GO:0060283 |
2 |
0.229
|
|
|
|
rostrocaudal neural tube patterning
|
GO:0021903 |
29 |
0.228
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
18 |
0.228
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.227
|
|
|
|
regulation of fibroblast growth factor receptor signaling pathway
|
GO:0040036 |
20 |
0.226
|
|
|
|
striated muscle cell development
|
GO:0055002 |
108 |
0.225
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
142 |
0.224
|
|
|
|
response to radiation
|
GO:0009314 |
51 |
0.223
|
|
|
|
fourth ventricle development
|
GO:0021592 |
8 |
0.222
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
3 |
0.222
|
|
|
|
camera type eye morphogenesis
|
GO:0048593 |
108 |
0.218
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
68 |
0.215
|
|
|
|
glomerulus development
|
GO:0032835 |
27 |
0.215
|
|
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.214
|
|
|
|
system process
|
GO:0003008 |
185 |
0.211
|
|
|
|
muscle organ development
|
GO:0007517 |
101 |
0.209
|
|
|
|
cellular component assembly
|
GO:0022607 |
170 |
0.205
|
|
|
|
cell cell signaling
|
GO:0007267 |
52 |
0.204
|
|
|
|
positive regulation of embryonic development
|
GO:0040019 |
3 |
0.202
|
|
|
|
regulation of gastrulation
|
GO:0010470 |
24 |
0.201
|
|
|
|
specification of symmetry
|
GO:0009799 |
204 |
0.201
|
|
|
|
endocrine system development
|
GO:0035270 |
65 |
0.201
|
|
|
|
endoderm development
|
GO:0007492 |
49 |
0.199
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
22 |
0.199
|
|
|
|
thrombocyte differentiation
|
GO:0002574 |
4 |
0.199
|
|
|
|
floor plate formation
|
GO:0021508 |
12 |
0.198
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
6 |
0.197
|
|
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.195
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
52 |
0.193
|
|
|
|
single organism localization
|
GO:1902578 |
225 |
0.191
|
|
|
|
gamete generation
|
GO:0007276 |
33 |
0.185
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.183
|
Fly |
|
|
otic placode formation
|
GO:0043049 |
23 |
0.180
|
|
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
71 |
0.179
|
|
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.179
|
Fly |
|
|
skeletal muscle tissue development
|
GO:0007519 |
67 |
0.178
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
47 |
0.176
|
|
|
|
axial mesoderm morphogenesis
|
GO:0048319 |
8 |
0.176
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
110 |
0.174
|
|
|
|
ventral midline development
|
GO:0007418 |
13 |
0.173
|
|
|
|
determination of heart left right asymmetry
|
GO:0061371 |
117 |
0.172
|
|
|
|
developmental growth
|
GO:0048589 |
166 |
0.170
|
|
|
|
segmentation
|
GO:0035282 |
97 |
0.170
|
|
|
|
neural plate pattern specification
|
GO:0060896 |
12 |
0.169
|
Zebrafish |
|
|
reproductive process
|
GO:0022414 |
40 |
0.168
|
|
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.167
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.165
|
|
|
|
endoderm formation
|
GO:0001706 |
29 |
0.164
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
63 |
0.160
|
|
|
|
cell death
|
GO:0008219 |
121 |
0.160
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
57 |
0.159
|
|
|
|
heart development
|
GO:0007507 |
313 |
0.159
|
|
|
|
muscle tissue development
|
GO:0060537 |
110 |
0.157
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
90 |
0.157
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
5 |
0.156
|
|
|
|
gene expression
|
GO:0010467 |
252 |
0.155
|
Fly |
|
|
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry
|
GO:1900094 |
17 |
0.153
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
39 |
0.152
|
|
|
|
blood circulation
|
GO:0008015 |
87 |
0.151
|
|
|
|
specification of organ position
|
GO:0010159 |
3 |
0.151
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
79 |
0.150
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
79 |
0.150
|
|
|
|
post anal tail morphogenesis
|
GO:0036342 |
19 |
0.150
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
216 |
0.150
|
|
|
|
negative regulation of mesodermal cell fate specification
|
GO:0042662 |
3 |
0.149
|
|
|
|
regulation of mesodermal cell fate specification
|
GO:0042661 |
9 |
0.148
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
34 |
0.147
|
|
|
|
cell proliferation
|
GO:0008283 |
80 |
0.143
|
|
|
|
ectodermal placode morphogenesis
|
GO:0071697 |
32 |
0.143
|
|
|
|
aging
|
GO:0007568 |
2 |
0.142
|
|
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.141
|
Fly |
|
|
neural plate regionalization
|
GO:0060897 |
10 |
0.141
|
Zebrafish |
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
45 |
0.140
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
40 |
0.139
|
|
|
|
specification of organ identity
|
GO:0010092 |
2 |
0.137
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
143 |
0.136
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
4 |
0.135
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
69 |
0.135
|
|
|
|
immune system process
|
GO:0002376 |
241 |
0.135
|
|
|
|
cellular response to organic substance
|
GO:0071310 |
105 |
0.134
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
87 |
0.134
|
|
|
|
bmp signaling pathway involved in heart development
|
GO:0061312 |
15 |
0.134
|
|
|
|
regulation of axon extension
|
GO:0030516 |
24 |
0.133
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
104 |
0.130
|
|
|
|
central nervous system segmentation
|
GO:0035283 |
6 |
0.128
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
42 |
0.128
|
|
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.126
|
|
|
|
wound healing
|
GO:0042060 |
90 |
0.126
|
|
|
|
response to stress
|
GO:0006950 |
263 |
0.124
|
|
|
|
wnt signaling pathway involved in digestive tract morphogenesis
|
GO:0044333 |
4 |
0.124
|
|
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.124
|
|
|
|
habenula development
|
GO:0021986 |
9 |
0.123
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
62 |
0.123
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
3 |
0.122
|
|
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.122
|
Fly |
|
|
spemann organizer formation at the embryonic shield
|
GO:0060063 |
2 |
0.121
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
13 |
0.121
|
|
|
|
multi organism process
|
GO:0051704 |
134 |
0.120
|
|
|
|
organ formation
|
GO:0048645 |
17 |
0.120
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
56 |
0.119
|
|
|
|
axial mesodermal cell fate specification
|
GO:0048327 |
3 |
0.118
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
213 |
0.117
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
18 |
0.116
|
|
|
|
mesodermal to mesenchymal transition involved in gastrulation
|
GO:0060809 |
1 |
0.116
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
53 |
0.116
|
|
|
|
embryonic axis specification
|
GO:0000578 |
12 |
0.115
|
|
|
|
response to growth factor
|
GO:0070848 |
39 |
0.115
|
|
|
|
regulation of localization
|
GO:0032879 |
104 |
0.115
|
|
|
|
skeletal system development
|
GO:0001501 |
181 |
0.113
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
2 |
0.112
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
1 |
0.111
|
|
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.111
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
68 |
0.109
|
|
|
|
regulation of transcription from rna polymerase ii promoter involved in heart development
|
GO:1901213 |
15 |
0.109
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
36 |
0.108
|
|
|
|
regulation of wnt signaling pathway involved in dorsal ventral axis specification
|
GO:2000053 |
5 |
0.108
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
48 |
0.107
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
74 |
0.105
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
139 |
0.104
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
33 |
0.103
|
|
|
|
cell adhesion
|
GO:0007155 |
40 |
0.102
|
|
|
|
ear morphogenesis
|
GO:0042471 |
64 |
0.102
|
|
|
|
inner ear development
|
GO:0048839 |
126 |
0.101
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
5 |
0.100
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
2 |
0.099
|
|
|
|
regulation of mesoderm development
|
GO:2000380 |
11 |
0.099
|
|
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.098
|
|
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.097
|
|
|
|
tissue regeneration
|
GO:0042246 |
74 |
0.097
|
|
|
|
gliogenesis
|
GO:0042063 |
45 |
0.097
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
22 |
0.096
|
|
|
|
developmental maturation
|
GO:0021700 |
34 |
0.095
|
|
|
|
cell growth
|
GO:0016049 |
57 |
0.094
|
|
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.092
|
|
|
|
single organism organelle organization
|
GO:1902589 |
199 |
0.092
|
|
|
|
neural plate anterior posterior regionalization
|
GO:0021999 |
8 |
0.091
|
Zebrafish |
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.090
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
30 |
0.089
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
4 |
0.088
|
|
|
|
muscle fiber development
|
GO:0048747 |
52 |
0.086
|
|
|
|
apoptotic process
|
GO:0006915 |
116 |
0.086
|
|
|
|
left right pattern formation
|
GO:0060972 |
19 |
0.084
|
|
|
|
maintenance of location
|
GO:0051235 |
4 |
0.083
|
|
|
|
oocyte development
|
GO:0048599 |
14 |
0.082
|
|
|
|
immune response
|
GO:0006955 |
28 |
0.082
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
64 |
0.082
|
|
|
|
death
|
GO:0016265 |
121 |
0.082
|
|
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.080
|
Fly |
|
|
neuron fate specification
|
GO:0048665 |
20 |
0.080
|
|
|
|
phosphorus metabolic process
|
GO:0006793 |
109 |
0.079
|
|
|
|
hindbrain development
|
GO:0030902 |
91 |
0.079
|
|
|
|
neuron fate commitment
|
GO:0048663 |
26 |
0.079
|
|
|
|
regulation of cell death
|
GO:0010941 |
103 |
0.078
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
18 |
0.078
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
77 |
0.078
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
42 |
0.077
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
14 |
0.076
|
|
|
|
otic vesicle formation
|
GO:0030916 |
27 |
0.076
|
|
|
|
reproduction
|
GO:0000003 |
40 |
0.076
|
|
|
|
cytoskeleton organization
|
GO:0007010 |
96 |
0.076
|
|
|
|
organelle organization
|
GO:0006996 |
227 |
0.076
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
1 |
0.075
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.075
|
|
|
|
ectoderm development
|
GO:0007398 |
9 |
0.075
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
29 |
0.075
|
|
|
|
determination of left right asymmetry in lateral mesoderm
|
GO:0003140 |
20 |
0.075
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
59 |
0.075
|
|
|
|
mesenchyme development
|
GO:0060485 |
127 |
0.074
|
|
|
|
regulation of axonogenesis
|
GO:0050770 |
32 |
0.074
|
|
|
|
pons development
|
GO:0021548 |
11 |
0.074
|
|
|
|
vasculature development
|
GO:0001944 |
278 |
0.074
|
|
|
|
pancreas development
|
GO:0031016 |
84 |
0.073
|
|
|
|
regulation of immune response
|
GO:0050776 |
14 |
0.072
|
|
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.072
|
Fly |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
1 |
0.071
|
|
|
|
mesenchymal cell proliferation
|
GO:0010463 |
1 |
0.071
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.071
|
|
|
|
single organism reproductive process
|
GO:0044702 |
40 |
0.070
|
|
|
|
embryonic pectoral fin morphogenesis
|
GO:0035118 |
24 |
0.069
|
|
|
|
inner ear receptor cell development
|
GO:0060119 |
20 |
0.069
|
|
|
|
intracellular transport
|
GO:0046907 |
32 |
0.069
|
|
|
|
spindle assembly involved in meiosis
|
GO:0090306 |
1 |
0.068
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.067
|
|
|
|
stem cell maintenance
|
GO:0019827 |
4 |
0.067
|
|
|
|
cartilage development
|
GO:0051216 |
96 |
0.066
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
56 |
0.066
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.066
|
|
|
|
pharyngeal muscle development
|
GO:0043282 |
4 |
0.065
|
|
|
|
determination of ventral identity
|
GO:0048264 |
21 |
0.065
|
|
|
|
neuron projection guidance
|
GO:0097485 |
86 |
0.064
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
18 |
0.063
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
22 |
0.063
|
|
|
|
wnt signaling pathway involved in dorsal ventral axis specification
|
GO:0044332 |
5 |
0.063
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
61 |
0.062
|
|
|
|
cellular protein metabolic process
|
GO:0044267 |
129 |
0.062
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
57 |
0.062
|
|
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.062
|
Fly |
|
|
regulation of cell migration
|
GO:0030334 |
40 |
0.062
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
52 |
0.061
|
|
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.061
|
|
|
|
neural nucleus development
|
GO:0048857 |
15 |
0.060
|
|
|
|
muscle cell development
|
GO:0055001 |
115 |
0.060
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
65 |
0.060
|
|
|
|
pigmentation
|
GO:0043473 |
85 |
0.059
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
77 |
0.059
|
|
|
|
otic vesicle development
|
GO:0071599 |
42 |
0.059
|
|
|
|
germ cell development
|
GO:0007281 |
22 |
0.059
|
|
|
|
blood vessel development
|
GO:0001568 |
246 |
0.059
|
|
|
|
single organism transport
|
GO:0044765 |
206 |
0.058
|
|
|
|
epiboly
|
GO:0090504 |
41 |
0.058
|
|
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.058
|
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.058
|
|
|
|
connective tissue development
|
GO:0061448 |
99 |
0.058
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
22 |
0.057
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
86 |
0.057
|
|
|
|
response to steroid hormone
|
GO:0048545 |
35 |
0.056
|
|
|
|
neural retina development
|
GO:0003407 |
49 |
0.056
|
|
|
|
protein import
|
GO:0017038 |
3 |
0.056
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
43 |
0.056
|
|
|
|
regulation of molecular function
|
GO:0065009 |
70 |
0.055
|
|
|
|
single organism cellular localization
|
GO:1902580 |
46 |
0.055
|
|
|
|
apoptotic process involved in development
|
GO:1902742 |
2 |
0.055
|
|
|
|
lateral line system development
|
GO:0048925 |
76 |
0.054
|
|
|
|
inner ear receptor cell differentiation
|
GO:0060113 |
29 |
0.054
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
148 |
0.054
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
204 |
0.053
|
|
|
|
stem cell development
|
GO:0048864 |
82 |
0.053
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
40 |
0.053
|
|
|
|
transport
|
GO:0006810 |
220 |
0.053
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
31 |
0.053
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
1 |
0.053
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
191 |
0.053
|
|
|
|
regulation of skeletal muscle tissue development
|
GO:0048641 |
4 |
0.053
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
54 |
0.052
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
14 |
0.051
|
|
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
93 |
0.051
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
11 |
0.051
|
|
|
|
locus ceruleus development
|
GO:0021703 |
3 |
0.051
|
|
|
|
cerebellum development
|
GO:0021549 |
17 |
0.051
|
|
|
|
trabecula formation
|
GO:0060343 |
2 |
0.051
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
68 |
0.051
|
|
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.050
|
|
|
|
regulation of cell motility
|
GO:2000145 |
46 |
0.050
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
45 |
0.050
|
|
|
|
kidney development
|
GO:0001822 |
92 |
0.050
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
274 |
0.050
|
|
|
|
cardiogenic plate morphogenesis
|
GO:0003142 |
1 |
0.050
|
|
|
|
axis elongation
|
GO:0003401 |
31 |
0.049
|
|
|
|
programmed cell death
|
GO:0012501 |
119 |
0.048
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
4 |
0.048
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.048
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
24 |
0.048
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
1 |
0.048
|
|
|
|
foregut morphogenesis
|
GO:0007440 |
4 |
0.048
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
178 |
0.048
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
35 |
0.047
|
|
|
|
epiboly involved in gastrulation with mouth forming second
|
GO:0055113 |
35 |
0.047
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
9 |
0.047
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
21 |
0.047
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
3 |
0.047
|
|
|
|
heart looping
|
GO:0001947 |
94 |
0.047
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
35 |
0.047
|
|
|
|
cardiac atrium morphogenesis
|
GO:0003209 |
2 |
0.047
|
|
|
|
lateral line development
|
GO:0048882 |
66 |
0.046
|
|
|
|
sensory perception of sound
|
GO:0007605 |
9 |
0.046
|
|
|
|
response to other organism
|
GO:0051707 |
97 |
0.046
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
2 |
0.046
|
|
|
|
cell cycle process
|
GO:0022402 |
53 |
0.045
|
|
|
|
regulation of system process
|
GO:0044057 |
40 |
0.045
|
|
|
|
fin development
|
GO:0033333 |
77 |
0.044
|
|
|
|
embryonic retina morphogenesis in camera type eye
|
GO:0060059 |
22 |
0.043
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
35 |
0.043
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
78 |
0.043
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
36 |
0.043
|
|
|
|
regulation of endodermal cell differentiation
|
GO:1903224 |
15 |
0.043
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
2 |
0.043
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
94 |
0.043
|
|
|
|
renal system development
|
GO:0072001 |
94 |
0.042
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
108 |
0.042
|
|
|
|
regulation of behavior
|
GO:0050795 |
24 |
0.042
|
|
|
|
steroid hormone mediated signaling pathway
|
GO:0043401 |
9 |
0.041
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
55 |
0.041
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
23 |
0.041
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
98 |
0.041
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
32 |
0.041
|
|
|
|
endodermal cell fate determination
|
GO:0007493 |
2 |
0.041
|
|
|
|
sensory system development
|
GO:0048880 |
76 |
0.041
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
3 |
0.040
|
|
|
|
female gonad development
|
GO:0008585 |
4 |
0.039
|
|
|
|
negative regulation of gastrulation
|
GO:2000542 |
11 |
0.039
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
43 |
0.039
|
|
|
|
neurological system process
|
GO:0050877 |
62 |
0.039
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
52 |
0.038
|
|
|
|
brain segmentation
|
GO:0035284 |
6 |
0.038
|
|
|
|
heart field specification
|
GO:0003128 |
1 |
0.038
|
|
|
|
stem cell division
|
GO:0017145 |
1 |
0.037
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
4 |
0.037
|
|
|
|
positive regulation of muscle organ development
|
GO:0048636 |
1 |
0.037
|
|
|
|
neural crest cell differentiation
|
GO:0014033 |
72 |
0.037
|
|
