Danio rerio

0 known processes

dio1

deiodinase, iodothyronine, type I

(Aliases: MGC174383,cb685,MGC92323,zgc:92323,Deio1)

dio1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.197
xenobiotic metabolic process GO:0006805 4 0.147
digestive system development GO:0055123 289 0.139
digestive tract development GO:0048565 265 0.121
estrogen metabolic process GO:0008210 2 0.107
response to drug GO:0042493 3 0.091
cellular response to xenobiotic stimulus GO:0071466 35 0.084
sensory organ morphogenesis GO:0090596 200 0.082
larval development GO:0002164 2 0.076
response to xenobiotic stimulus GO:0009410 45 0.069
organic substance biosynthetic process GO:1901576 289 0.068
cellular biosynthetic process GO:0044249 286 0.065
single organism metabolic process GO:0044710 217 0.063
embryonic organ morphogenesis GO:0048562 274 0.062
camera type eye development GO:0043010 222 0.061
biosynthetic process GO:0009058 294 0.059
secondary metabolic process GO:0019748 3 0.058
ameboidal type cell migration GO:0001667 143 0.057
single organism biosynthetic process GO:0044711 71 0.052
phagocytosis GO:0006909 3 0.052
digestive tract morphogenesis GO:0048546 231 0.050
lipid catabolic process GO:0016042 4 0.050
cellular amino acid metabolic process GO:0006520 7 0.049
organic cyclic compound biosynthetic process GO:1901362 223 0.049
heart development GO:0007507 313 0.049
eye development GO:0001654 277 0.048
carbohydrate biosynthetic process GO:0016051 1 0.047
embryonic organ development GO:0048568 381 0.046
small molecule metabolic process GO:0044281 77 0.045
organic acid metabolic process GO:0006082 31 0.043
system process GO:0003008 185 0.043
regulation of cellular metabolic process GO:0031323 320 0.043
single organism organelle organization GO:1902589 199 0.042
determination of bilateral symmetry GO:0009855 204 0.042
stem cell proliferation GO:0072089 4 0.041
cellular component biogenesis GO:0044085 178 0.040
gtp catabolic process GO:0006184 2 0.040
retina development in camera type eye GO:0060041 146 0.039
organonitrogen compound metabolic process GO:1901564 74 0.039
cortical cytoskeleton organization GO:0030865 1 0.039
cellular aromatic compound metabolic process GO:0006725 295 0.039
cell migration GO:0016477 237 0.038
blood vessel morphogenesis GO:0048514 216 0.038
nitrogen compound metabolic process GO:0006807 319 0.037
cellular hormone metabolic process GO:0034754 19 0.035
vasculature development GO:0001944 278 0.035
single fertilization GO:0007338 3 0.034
regulation of protein complex assembly GO:0043254 3 0.034
head development GO:0060322 303 0.034
mesenchyme development GO:0060485 127 0.033
nitric oxide metabolic process GO:0046209 2 0.033
positive regulation of transport GO:0051050 2 0.033
positive regulation of cellular component biogenesis GO:0044089 3 0.033
actin filament based process GO:0030029 64 0.033
regulation of biological quality GO:0065008 263 0.032
ear morphogenesis GO:0042471 64 0.032
toxin metabolic process GO:0009404 1 0.032
fin development GO:0033333 77 0.032
stem cell maintenance GO:0019827 4 0.031
maintenance of location GO:0051235 4 0.031
regulation of nucleocytoplasmic transport GO:0046822 2 0.031
neurological system process GO:0050877 62 0.031
response to glucocorticoid GO:0051384 1 0.031
androgen metabolic process GO:0008209 2 0.031
skeletal system development GO:0001501 181 0.031
mesoderm development GO:0007498 88 0.031
regulation of intracellular protein transport GO:0033157 3 0.030
response to stress GO:0006950 263 0.030
positive regulation of cell cycle GO:0045787 3 0.030
negative regulation of biological process GO:0048519 304 0.029
cognition GO:0050890 1 0.029
organic cyclic compound metabolic process GO:1901360 301 0.029
guanosine containing compound metabolic process GO:1901068 4 0.029
negative regulation of rna biosynthetic process GO:1902679 45 0.029
appendage development GO:0048736 80 0.029
regulation of protein import into nucleus GO:0042306 2 0.028
growth GO:0040007 174 0.028
immune system development GO:0002520 191 0.028
purine nucleoside monophosphate catabolic process GO:0009128 4 0.027
gene expression GO:0010467 252 0.027
sensory perception of chemical stimulus GO:0007606 3 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
heterocycle biosynthetic process GO:0018130 215 0.027
cellular macromolecule metabolic process GO:0044260 391 0.026
negative regulation of protein kinase activity GO:0006469 4 0.026
cellular component assembly GO:0022607 170 0.026
multicellular organism growth GO:0035264 4 0.026
gtp metabolic process GO:0046039 4 0.026
neuroblast proliferation GO:0007405 2 0.026
oxoacid metabolic process GO:0043436 31 0.026
angiogenesis GO:0001525 158 0.026
aging GO:0007568 2 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.025
cellular modified amino acid metabolic process GO:0006575 3 0.025
ether metabolic process GO:0018904 1 0.025
response to alkaloid GO:0043279 2 0.025
nuclear transport GO:0051169 4 0.025
gastrulation GO:0007369 208 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.024
synaptic growth at neuromuscular junction GO:0051124 2 0.024
signal transduction GO:0007165 455 0.024
meiotic nuclear division GO:0007126 4 0.024
regulation of meiotic cell cycle GO:0051445 1 0.024
cell projection morphogenesis GO:0048858 244 0.024
organelle organization GO:0006996 227 0.024
developmental growth GO:0048589 166 0.024
response to organic cyclic compound GO:0014070 51 0.024
morphogenesis of an epithelium GO:0002009 333 0.024
regulation of protein targeting GO:1903533 2 0.024
cellular component morphogenesis GO:0032989 336 0.024
regulation of protein transport GO:0051223 3 0.024
heterocycle metabolic process GO:0046483 290 0.023
transport GO:0006810 220 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
liver development GO:0001889 96 0.023
cellular amine metabolic process GO:0044106 2 0.023
chordate embryonic development GO:0043009 271 0.023
regulation of primary metabolic process GO:0080090 311 0.023
response to chemical GO:0042221 320 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
negative regulation of gene expression GO:0010629 65 0.023
amine metabolic process GO:0009308 2 0.022
negative regulation of macromolecule metabolic process GO:0010605 76 0.022
gland development GO:0048732 143 0.022
multi organism process GO:0051704 134 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
cellular nitrogen compound metabolic process GO:0034641 290 0.022
establishment of localization GO:0051234 244 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
regulation of reproductive process GO:2000241 4 0.021
response to wounding GO:0009611 116 0.021
pancreas development GO:0031016 84 0.021
cellular ketone metabolic process GO:0042180 11 0.021
regulation of cytokine production GO:0001817 3 0.021
segmentation GO:0035282 97 0.021
response to organic substance GO:0010033 153 0.021
fat soluble vitamin biosynthetic process GO:0042362 2 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
hatching GO:0035188 4 0.021
hepaticobiliary system development GO:0061008 98 0.020
cilium morphogenesis GO:0060271 85 0.020
cellular carbohydrate metabolic process GO:0044262 4 0.020
protein import GO:0017038 3 0.020
regulation of gtpase activity GO:0043087 2 0.020
positive regulation of catabolic process GO:0009896 4 0.020
reactive oxygen species biosynthetic process GO:1903409 1 0.020
lipid storage GO:0019915 1 0.020
multicellular organismal response to stress GO:0033555 2 0.020
urogenital system development GO:0001655 97 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
nuclear migration GO:0007097 3 0.020
ear development GO:0043583 127 0.020
inner ear development GO:0048839 126 0.020
sensory perception of pain GO:0019233 1 0.020
regulation of gene expression GO:0010468 265 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
alpha amino acid metabolic process GO:1901605 3 0.019
protein targeting to nucleus GO:0044744 3 0.019
regulation of signal transduction GO:0009966 225 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.019
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.019
blood vessel development GO:0001568 246 0.019
neurotransmitter transport GO:0006836 2 0.019
meiotic cell cycle process GO:1903046 3 0.019
inner ear morphogenesis GO:0042472 63 0.019
single organism nuclear import GO:1902593 3 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.019
actin polymerization or depolymerization GO:0008154 2 0.019
guanosine containing compound catabolic process GO:1901069 2 0.018
response to endogenous stimulus GO:0009719 83 0.018
cellular response to external stimulus GO:0071496 2 0.018
regulation of biosynthetic process GO:0009889 250 0.018
mitochondrion organization GO:0007005 4 0.018
tube morphogenesis GO:0035239 349 0.018
regulation of circadian rhythm GO:0042752 4 0.018
apoptotic process involved in development GO:1902742 2 0.018
positive regulation of lipid metabolic process GO:0045834 1 0.018
positive regulation of cytoskeleton organization GO:0051495 3 0.018
response to corticosteroid GO:0031960 1 0.018
calcium ion import GO:0070509 4 0.018
membrane invagination GO:0010324 1 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
diterpenoid metabolic process GO:0016101 15 0.017
fertilization GO:0009566 3 0.017
energy reserve metabolic process GO:0006112 2 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.017
positive regulation of cytokine production GO:0001819 2 0.017
response to ketone GO:1901654 1 0.017
regulation of neural precursor cell proliferation GO:2000177 3 0.017
regulation of binding GO:0051098 3 0.017
regulation of reactive oxygen species metabolic process GO:2000377 2 0.017
oxidation reduction process GO:0055114 41 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.017
hormone transport GO:0009914 2 0.017
lipid metabolic process GO:0006629 52 0.017
cellular component movement GO:0006928 335 0.017
response to amine GO:0014075 1 0.017
negative regulation of defense response GO:0031348 2 0.017
regulation of stem cell differentiation GO:2000736 4 0.017
negative regulation of protein complex assembly GO:0031333 1 0.017
regulation of anatomical structure morphogenesis GO:0022603 130 0.017
skeletal system morphogenesis GO:0048705 102 0.017
cell morphogenesis GO:0000902 289 0.016
response to hormone GO:0009725 48 0.016
regulation of transcription dna templated GO:0006355 213 0.016
peptidyl serine phosphorylation GO:0018105 1 0.016
locomotion GO:0040011 313 0.016
cell motility GO:0048870 244 0.016
phagocytosis engulfment GO:0006911 1 0.016
regulation of wound healing GO:0061041 2 0.016
germ line stem cell maintenance GO:0030718 2 0.016
regulation of inflammatory response GO:0050727 2 0.016
negative regulation of signaling GO:0023057 96 0.016
positive regulation of cell activation GO:0050867 1 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
androgen biosynthetic process GO:0006702 1 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
striated muscle cell development GO:0055002 108 0.016
regulation of cell activation GO:0050865 1 0.016
cell projection assembly GO:0030031 64 0.016
nucleic acid templated transcription GO:0097659 181 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
nuclear import GO:0051170 3 0.016
regulation of nitrogen compound metabolic process GO:0051171 251 0.016
circulatory system process GO:0003013 87 0.015
positive regulation of secretion GO:0051047 1 0.015
monoamine transport GO:0015844 1 0.015
negative regulation of cellular process GO:0048523 283 0.015
response to lipid GO:0033993 60 0.015
cellular macromolecule biosynthetic process GO:0034645 224 0.015
hormone biosynthetic process GO:0042446 3 0.015
protein import into nucleus GO:0006606 3 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
cellular response to organic substance GO:0071310 105 0.015
catecholamine metabolic process GO:0006584 2 0.015
negative regulation of biosynthetic process GO:0009890 55 0.015
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.015
regulation of dendrite development GO:0050773 3 0.015
regulation of tube size GO:0035150 2 0.015
determination of left right symmetry GO:0007368 179 0.015
protein complex disassembly GO:0043241 1 0.015
regulation of response to stimulus GO:0048583 269 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
response to carbohydrate GO:0009743 3 0.014
heart contraction GO:0060047 71 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
single organism transport GO:0044765 206 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
response to uv GO:0009411 3 0.014
dopamine metabolic process GO:0042417 2 0.014
regulation of protein catabolic process GO:0042176 1 0.014
regulation of synapse assembly GO:0051963 3 0.014
neurotransmitter secretion GO:0007269 2 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
phototransduction GO:0007602 2 0.014
response to hexose GO:0009746 3 0.014
response to external stimulus GO:0009605 264 0.014
autophagy GO:0006914 4 0.014
peptidyl serine modification GO:0018209 2 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
regulation of nervous system development GO:0051960 90 0.014
eye morphogenesis GO:0048592 144 0.014
negative regulation of cellular biosynthetic process GO:0031327 55 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
regulation of protein polymerization GO:0032271 2 0.014
regulation of organelle organization GO:0033043 29 0.014
stem cell development GO:0048864 82 0.014
fin morphogenesis GO:0033334 53 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
lamellipodium organization GO:0097581 1 0.014
pectoral fin development GO:0033339 50 0.014
fat soluble vitamin metabolic process GO:0006775 4 0.014
cortical actin cytoskeleton organization GO:0030866 1 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
cellular response to estradiol stimulus GO:0071392 1 0.013
neural crest cell development GO:0014032 62 0.013
negative regulation of reproductive process GO:2000242 3 0.013
developmental programmed cell death GO:0010623 4 0.013
negative regulation of cell communication GO:0010648 96 0.013
centrosome organization GO:0051297 1 0.013
regulation of blood vessel size GO:0050880 2 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
regulation of autophagy GO:0010506 3 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
regulation of cell shape GO:0008360 1 0.013
regulation of metabolic process GO:0019222 359 0.013
adult behavior GO:0030534 2 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
cellular amino acid biosynthetic process GO:0008652 2 0.013
photoreceptor cell development GO:0042461 40 0.013
renal system development GO:0072001 94 0.013
locomotor rhythm GO:0045475 3 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
cilium assembly GO:0042384 58 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
kidney development GO:0001822 92 0.013
response to abiotic stimulus GO:0009628 122 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
negative regulation of rna metabolic process GO:0051253 48 0.012
cell surface receptor signaling pathway GO:0007166 325 0.012
cellular response to starvation GO:0009267 1 0.012
macromolecular complex disassembly GO:0032984 1 0.012
regulation of apoptotic process GO:0042981 98 0.012
cellular response to hormone stimulus GO:0032870 39 0.012
response to glucose GO:0009749 3 0.012
cell cycle arrest GO:0007050 1 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
aflatoxin metabolic process GO:0046222 1 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
post embryonic organ development GO:0048569 4 0.012
tissue regeneration GO:0042246 74 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
regulation of mrna processing GO:0050684 3 0.012
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.012
hormone metabolic process GO:0042445 19 0.012
rna metabolic process GO:0016070 219 0.012
negative regulation of protein transport GO:0051224 3 0.012
connective tissue development GO:0061448 99 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
negative regulation of transcription dna templated GO:0045892 45 0.012
negative regulation of metabolic process GO:0009892 86 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
regulation of cell development GO:0060284 100 0.012
protein localization to nucleus GO:0034504 3 0.012
cellular biogenic amine metabolic process GO:0006576 2 0.012
cellular protein catabolic process GO:0044257 4 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
epithelial cell differentiation GO:0030855 116 0.012
tissue remodeling GO:0048771 4 0.012
nucleobase containing compound metabolic process GO:0006139 274 0.012
organism emergence from protective structure GO:0071684 4 0.012
sensory system development GO:0048880 76 0.012
small molecule catabolic process GO:0044282 3 0.012
rna biosynthetic process GO:0032774 181 0.011
lateral inhibition GO:0046331 1 0.011
cilium organization GO:0044782 71 0.011
regulation of signaling GO:0023051 235 0.011
hormone secretion GO:0046879 2 0.011
alcohol biosynthetic process GO:0046165 2 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
translational initiation GO:0006413 3 0.011
mesenchymal cell differentiation GO:0048762 87 0.011
regulation of developmental process GO:0050793 247 0.011
glial cell differentiation GO:0010001 42 0.011
interaction with host GO:0051701 4 0.011
specification of symmetry GO:0009799 204 0.011
purine ribonucleoside biosynthetic process GO:0046129 2 0.011
exocytosis GO:0006887 1 0.011
response to other organism GO:0051707 97 0.011
cartilage development GO:0051216 96 0.011
wound healing GO:0042060 90 0.011
viral process GO:0016032 1 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
ventricular cardiac muscle tissue development GO:0003229 3 0.011
pericardium development GO:0060039 1 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
heart process GO:0003015 71 0.011
nucleic acid metabolic process GO:0090304 244 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
negative regulation of dna replication GO:0008156 2 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
multi organism cellular process GO:0044764 2 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
interspecies interaction between organisms GO:0044419 4 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.011
pathway restricted smad protein phosphorylation GO:0060389 1 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
blood circulation GO:0008015 87 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.010
smad protein complex assembly GO:0007183 1 0.010
regulation of dna replication GO:0006275 3 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.010
somatic muscle development GO:0007525 4 0.010
ubiquitin dependent protein catabolic process GO:0006511 3 0.010
protein metabolic process GO:0019538 183 0.010
neuron neuron synaptic transmission GO:0007270 1 0.010
apoptotic process involved in morphogenesis GO:0060561 2 0.010
regulation of nucleic acid templated transcription GO:1903506 213 0.010
regulation of bmp signaling pathway GO:0030510 39 0.010
cell death GO:0008219 121 0.010
central nervous system development GO:0007417 387 0.010
bmp signaling pathway GO:0030509 52 0.010
protein homooligomerization GO:0051260 3 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
internal protein amino acid acetylation GO:0006475 2 0.010
negative regulation of map kinase activity GO:0043407 2 0.010
regulation of localization GO:0032879 104 0.010
reactive oxygen species metabolic process GO:0072593 6 0.010
response to monosaccharide GO:0034284 3 0.010
regulation of synaptic plasticity GO:0048167 1 0.010

dio1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.021
cardiovascular system disease DOID:1287 0 0.020
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011