Danio rerio

108 known processes

dkk1b

dickkopf 1b

(Aliases: MGC152787,dkk1)

dkk1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
digestive tract morphogenesis GO:0048546 231 0.983
dorsal ventral pattern formation GO:0009953 125 0.982
sensory organ development GO:0007423 393 0.976
regionalization GO:0003002 274 0.974
Mouse
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.950
cell fate commitment GO:0045165 99 0.940
Mouse
embryonic organ development GO:0048568 381 0.940
regulation of nitrogen compound metabolic process GO:0051171 251 0.935
Mouse
locomotion GO:0040011 313 0.933
digestive tract development GO:0048565 265 0.932
digestive system development GO:0055123 289 0.929
optic placode formation GO:0001743 4 0.922
ectodermal placode development GO:0071696 37 0.905
somite development GO:0061053 96 0.903
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.894
Mouse
central nervous system development GO:0007417 387 0.883
nitrogen compound metabolic process GO:0006807 319 0.881
Mouse
cell fate specification GO:0001708 68 0.880
Mouse
regulation of transcription dna templated GO:0006355 213 0.866
Mouse
macromolecule biosynthetic process GO:0009059 227 0.863
Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.862
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.849
Mouse
determination of dorsal ventral asymmetry GO:0048262 34 0.846
endocrine pancreas development GO:0031018 27 0.839
cellular component movement GO:0006928 335 0.837
nucleobase containing compound metabolic process GO:0006139 274 0.832
Mouse
optic placode formation involved in camera type eye formation GO:0046619 3 0.828
stem cell proliferation GO:0072089 4 0.826
heterocycle metabolic process GO:0046483 290 0.823
Mouse
gland development GO:0048732 143 0.817
regulation of cellular metabolic process GO:0031323 320 0.817
Mouse
regulation of gene expression GO:0010468 265 0.817
Mouse
cell proliferation GO:0008283 80 0.806
rna biosynthetic process GO:0032774 181 0.805
Mouse
liver development GO:0001889 96 0.802
organic cyclic compound biosynthetic process GO:1901362 223 0.796
Mouse
neuron differentiation GO:0030182 353 0.794
regulation of metabolic process GO:0019222 359 0.783
Mouse
regulation of signaling GO:0023051 235 0.780
transcription dna templated GO:0006351 181 0.780
Mouse
positive regulation of signaling GO:0023056 56 0.777
Mouse
regulation of rna metabolic process GO:0051252 224 0.772
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.772
Mouse
regeneration GO:0031099 91 0.762
positive regulation of cellular process GO:0048522 201 0.759
Mouse
gliogenesis GO:0042063 45 0.756
neuron projection guidance GO:0097485 86 0.726
cell motility GO:0048870 244 0.724
nucleic acid metabolic process GO:0090304 244 0.724
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.714
Mouse
hepatic duct development GO:0061011 2 0.713
generation of neurons GO:0048699 385 0.708
mechanosensory lateral line system development GO:0048881 49 0.701
blood vessel development GO:0001568 246 0.695
gall bladder development GO:0061010 1 0.690
forebrain development GO:0030900 96 0.684
spemann organizer formation GO:0060061 10 0.672
organic cyclic compound metabolic process GO:1901360 301 0.669
Mouse
eye development GO:0001654 277 0.668
regulation of response to stimulus GO:0048583 269 0.666
gastrulation GO:0007369 208 0.660
regulation of macromolecule biosynthetic process GO:0010556 225 0.648
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.646
Mouse
response to wounding GO:0009611 116 0.644
regulation of phosphate metabolic process GO:0019220 43 0.643
convergent extension involved in gastrulation GO:0060027 71 0.639
specification of symmetry GO:0009799 204 0.637
embryonic organ morphogenesis GO:0048562 274 0.637
cellular nitrogen compound metabolic process GO:0034641 290 0.635
Mouse
mesoderm morphogenesis GO:0048332 51 0.627
Mouse
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.623
blood vessel morphogenesis GO:0048514 216 0.622
negative regulation of biological process GO:0048519 304 0.620
immune system process GO:0002376 241 0.619
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.605
Mouse
regulation of signal transduction GO:0009966 225 0.604
sensory organ morphogenesis GO:0090596 200 0.604
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.603
Mouse
gene expression GO:0010467 252 0.601
Mouse
axis specification GO:0009798 43 0.596
hindbrain development GO:0030902 91 0.592
signal transduction GO:0007165 455 0.590
hepaticobiliary system development GO:0061008 98 0.590
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.583
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.581
morphogenesis of an epithelium GO:0002009 333 0.581
regulation of rna biosynthetic process GO:2001141 213 0.580
Mouse
neuromast development GO:0048884 46 0.574
regulation of primary metabolic process GO:0080090 311 0.568
Mouse
determination of ventral identity GO:0048264 21 0.560
ear morphogenesis GO:0042471 64 0.559
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.558
wound healing GO:0042060 90 0.553
rostrocaudal neural tube patterning GO:0021903 29 0.551
pathway restricted smad protein phosphorylation GO:0060389 1 0.551
positive regulation of jun kinase activity GO:0043507 2 0.538
transcription from rna polymerase ii promoter GO:0006366 80 0.536
Mouse
dorsal convergence GO:0060030 14 0.532
hematopoietic or lymphoid organ development GO:0048534 191 0.532
brain development GO:0007420 293 0.528
lateral line system development GO:0048925 76 0.527
tissue regeneration GO:0042246 74 0.527
anterior head development GO:0097065 2 0.524
chordate embryonic development GO:0043009 271 0.523
Mouse
negative regulation of embryonic development GO:0045992 11 0.520
intracellular signal transduction GO:0035556 85 0.520
otolith development GO:0048840 32 0.514
determination of left right symmetry GO:0007368 179 0.514
regulation of synapse organization GO:0050807 3 0.509
embryonic camera type eye development GO:0031076 29 0.508
regulation of heart morphogenesis GO:2000826 17 0.500
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.499
Mouse
axonogenesis GO:0007409 152 0.497
heart development GO:0007507 313 0.496
cell morphogenesis GO:0000902 289 0.494
Mouse
embryonic limb morphogenesis GO:0030326 2 0.494
Mouse
regulation of cell differentiation GO:0045595 142 0.492
Mouse
larval development GO:0002164 2 0.492
cell differentiation in hindbrain GO:0021533 5 0.490
regulation of gastrulation GO:0010470 24 0.487
regulation of nucleic acid templated transcription GO:1903506 213 0.486
Mouse
regulation of phosphorus metabolic process GO:0051174 43 0.485
positive regulation of cell communication GO:0010647 56 0.483
Mouse
pituitary gland development GO:0021983 16 0.481
ectodermal placode formation GO:0060788 26 0.480
head development GO:0060322 303 0.480
rna metabolic process GO:0016070 219 0.479
Mouse
response to chemical GO:0042221 320 0.477
Mouse
regulation of cell communication GO:0010646 232 0.477
nephron morphogenesis GO:0072028 2 0.476
dorsal ventral axis specification GO:0009950 14 0.462
mesodermal cell differentiation GO:0048333 21 0.462
determination of heart left right asymmetry GO:0061371 117 0.460
negative regulation of nuclear division GO:0051784 3 0.458
response to external stimulus GO:0009605 264 0.458
odontogenesis of dentin containing tooth GO:0042475 1 0.456
metencephalon development GO:0022037 27 0.453
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.453
nucleic acid templated transcription GO:0097659 181 0.450
Mouse
negative regulation of cell fate specification GO:0009996 11 0.442
cellular nitrogen compound biosynthetic process GO:0044271 218 0.439
Mouse
cellular component morphogenesis GO:0032989 336 0.421
Mouse
appendage development GO:0048736 80 0.420
Mouse
regulation of multicellular organismal process GO:0051239 277 0.419
Mouse
determination of left right asymmetry in diencephalon GO:0035462 4 0.418
protein targeting to nucleus GO:0044744 3 0.417
biosynthetic process GO:0009058 294 0.416
Mouse
phosphorus metabolic process GO:0006793 109 0.416
embryonic camera type eye formation GO:0060900 10 0.411
cell differentiation in spinal cord GO:0021515 40 0.408
endodermal cell fate specification GO:0001714 17 0.408
axon guidance GO:0007411 86 0.404
ectodermal placode morphogenesis GO:0071697 32 0.397
death GO:0016265 121 0.396
regulation of anatomical structure morphogenesis GO:0022603 130 0.394
Mouse
neuroblast proliferation GO:0007405 2 0.393
renal tubule morphogenesis GO:0061333 1 0.392
immune system development GO:0002520 191 0.391
stem cell maintenance GO:0019827 4 0.385
regulation of anterior head development GO:2000742 2 0.385
nephron epithelium morphogenesis GO:0072088 1 0.384
embryonic heart tube development GO:0035050 133 0.384
cell projection organization GO:0030030 284 0.379
epithelium regeneration GO:1990399 14 0.376
posterior lateral line development GO:0048916 38 0.373
negative regulation of gastrulation GO:2000542 11 0.368
regulation of cell death GO:0010941 103 0.367
muscle tissue development GO:0060537 110 0.364
Mouse
camera type eye development GO:0043010 222 0.363
mesoderm formation GO:0001707 43 0.361
Mouse
regulation of cell fate commitment GO:0010453 22 0.358
Mouse
heart morphogenesis GO:0003007 156 0.355
thrombocyte differentiation GO:0002574 4 0.355
positive regulation of response to stimulus GO:0048584 80 0.353
regulation of biosynthetic process GO:0009889 250 0.351
Mouse
diencephalon development GO:0021536 58 0.348
cell surface receptor signaling pathway GO:0007166 325 0.347
taxis GO:0042330 109 0.347
organelle organization GO:0006996 227 0.342
response to stress GO:0006950 263 0.340
mesodermal cell fate commitment GO:0001710 14 0.340
regulation of endodermal cell fate specification GO:0042663 15 0.339
anterior posterior pattern specification GO:0009952 152 0.337
Mouse
lateral line development GO:0048882 66 0.336
heart jogging GO:0003146 40 0.335
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.335
specification of axis polarity GO:0065001 4 0.334
positive regulation of biological process GO:0048518 253 0.334
Mouse
heart looping GO:0001947 94 0.332
central nervous system neuron differentiation GO:0021953 74 0.327
phosphate containing compound metabolic process GO:0006796 108 0.323
embryonic appendage morphogenesis GO:0035113 30 0.322
Mouse
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.321
tube morphogenesis GO:0035239 349 0.320
neural tube patterning GO:0021532 33 0.320
hepatocyte proliferation GO:0072574 2 0.316
cellular response to stress GO:0033554 62 0.316
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.315
muscle structure development GO:0061061 196 0.315
Mouse
notochord development GO:0030903 54 0.313
negative regulation of cell fate commitment GO:0010454 13 0.313
notochord morphogenesis GO:0048570 17 0.308
cell migration GO:0016477 237 0.307
heart field specification GO:0003128 1 0.306
regulation of cell fate specification GO:0042659 20 0.305
Mouse
striated muscle tissue development GO:0014706 110 0.302
Mouse
regulation of multicellular organismal development GO:2000026 223 0.298
Mouse
negative regulation of cellular process GO:0048523 283 0.293
muscle organ development GO:0007517 101 0.288
Mouse
hemopoiesis GO:0030097 183 0.285
regulation of cell migration GO:0030334 40 0.284
bmp signaling pathway GO:0030509 52 0.284
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.283
Mouse
localization of cell GO:0051674 244 0.283
forebrain generation of neurons GO:0021872 14 0.281
eye morphogenesis GO:0048592 144 0.279
protein metabolic process GO:0019538 183 0.277
vasculature development GO:0001944 278 0.277
positive regulation of epithelial cell differentiation GO:0030858 2 0.275
heterocycle biosynthetic process GO:0018130 215 0.275
Mouse
positive regulation of biosynthetic process GO:0009891 68 0.274
phosphorylation GO:0016310 69 0.273
embryonic eye morphogenesis GO:0048048 30 0.271
neuron development GO:0048666 262 0.270
inner ear morphogenesis GO:0042472 63 0.270
fin regeneration GO:0031101 51 0.268
neural plate pattern specification GO:0060896 12 0.267
retina development in camera type eye GO:0060041 146 0.266
single organism metabolic process GO:0044710 217 0.266
inner ear development GO:0048839 126 0.264
somitogenesis GO:0001756 87 0.261
Mouse
swim bladder development GO:0048794 19 0.259
embryonic camera type eye morphogenesis GO:0048596 19 0.256
pancreas development GO:0031016 84 0.253
spinal cord development GO:0021510 46 0.249
regulation of response to stress GO:0080134 36 0.249
cell morphogenesis involved in differentiation GO:0000904 195 0.244
Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.240
sensory epithelium regeneration GO:0070654 14 0.239
negative regulation of cell differentiation GO:0045596 46 0.238
thalamus development GO:0021794 6 0.237
aromatic compound biosynthetic process GO:0019438 217 0.235
Mouse
regulation of organ morphogenesis GO:2000027 35 0.228
Mouse
organonitrogen compound metabolic process GO:1901564 74 0.227
cell cycle GO:0007049 93 0.226
determination of dorsal identity GO:0048263 13 0.225
mitotic cell cycle GO:0000278 64 0.224
negative regulation of muscle organ development GO:0048635 5 0.223
Mouse
glial cell differentiation GO:0010001 42 0.222
organic substance biosynthetic process GO:1901576 289 0.221
Mouse
response to organic substance GO:0010033 153 0.220
Mouse
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.219
common bile duct development GO:0061009 13 0.218
regulation of embryonic development GO:0045995 47 0.217
negative regulation of mitosis GO:0045839 3 0.216
protein import GO:0017038 3 0.215
establishment of protein localization to organelle GO:0072594 4 0.212
regulation of jun kinase activity GO:0043506 3 0.212
myotube differentiation GO:0014902 45 0.211
skeletal muscle tissue development GO:0007519 67 0.208
Mouse
apoptotic process GO:0006915 116 0.208
cell cell signaling GO:0007267 52 0.202
Mouse
protein localization to nucleus GO:0034504 3 0.201
nucleobase containing compound biosynthetic process GO:0034654 205 0.201
Mouse
positive regulation of jnk cascade GO:0046330 3 0.201
negative regulation of endodermal cell differentiation GO:1903225 8 0.198
neuron projection morphogenesis GO:0048812 161 0.197
cell part morphogenesis GO:0032990 246 0.196
growth GO:0040007 174 0.194
neural plate regionalization GO:0060897 10 0.194
development of primary female sexual characteristics GO:0046545 4 0.193
sensory system development GO:0048880 76 0.193
endoderm development GO:0007492 49 0.192
Mouse
cytoskeleton organization GO:0007010 96 0.192
positive regulation of transcription dna templated GO:0045893 57 0.191
striated muscle cell differentiation GO:0051146 129 0.189
neuron projection development GO:0031175 180 0.187
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.186
embryonic skeletal system morphogenesis GO:0048704 93 0.185
muscle cell differentiation GO:0042692 139 0.183
protein import into nucleus GO:0006606 3 0.182
endocrine system development GO:0035270 65 0.180
nephron tubule morphogenesis GO:0072078 1 0.180
regulation of skeletal muscle tissue development GO:0048641 4 0.178
Mouse
regulation of reproductive process GO:2000241 4 0.175
embryo development ending in birth or egg hatching GO:0009792 271 0.175
Mouse
determination of bilateral symmetry GO:0009855 204 0.174
endodermal cell differentiation GO:0035987 19 0.174
ear development GO:0043583 127 0.173
non canonical wnt signaling pathway GO:0035567 13 0.172
positive regulation of metabolic process GO:0009893 108 0.169
negative regulation of phosphate metabolic process GO:0045936 13 0.168
stem cell division GO:0017145 1 0.166
spinal cord anterior posterior patterning GO:0021512 1 0.164
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.163
non canonical wnt signaling pathway involved in heart development GO:0061341 2 0.162
axon development GO:0061564 166 0.161
positive regulation of signal transduction GO:0009967 56 0.160
negative regulation of muscle tissue development GO:1901862 2 0.159
Mouse
regulation of neurogenesis GO:0050767 87 0.156
mitotic cell cycle process GO:1903047 48 0.155
macromolecule modification GO:0043412 111 0.155
positive regulation of stress activated mapk cascade GO:0032874 3 0.154
mediolateral intercalation GO:0060031 3 0.153
regulation of programmed cell death GO:0043067 101 0.152
negative regulation of endodermal cell fate specification GO:0042664 8 0.152
cell migration involved in gastrulation GO:0042074 79 0.151
calcium ion transport into cytosol GO:0060402 3 0.150
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.150
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.150
embryonic pattern specification GO:0009880 44 0.149
chemotaxis GO:0006935 104 0.149
carbohydrate derivative metabolic process GO:1901135 61 0.149
regulation of cellular response to growth factor stimulus GO:0090287 35 0.149
single organism organelle organization GO:1902589 199 0.147
positive regulation of cellular component biogenesis GO:0044089 3 0.145
regulation of developmental process GO:0050793 247 0.144
Mouse
nucleocytoplasmic transport GO:0006913 4 0.144
negative regulation of nucleic acid templated transcription GO:1903507 45 0.143
Mouse
negative regulation of transcription dna templated GO:0045892 45 0.141
Mouse
embryonic skeletal joint morphogenesis GO:0060272 3 0.140
wnt signaling pathway calcium modulating pathway GO:0007223 5 0.139
signal transduction by phosphorylation GO:0023014 18 0.139
cellular component assembly GO:0022607 170 0.138
negative regulation of signaling GO:0023057 96 0.138
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.138
small molecule metabolic process GO:0044281 77 0.137
negative regulation of wnt signaling pathway involved in heart development GO:0003308 2 0.137
Mouse
positive regulation of gene expression GO:0010628 71 0.136
endocardium morphogenesis GO:0003160 4 0.136
regulation of cell development GO:0060284 100 0.136
spinal cord radial glial cell differentiation GO:0021531 2 0.135
cellular biosynthetic process GO:0044249 286 0.132
Mouse
regulation of cellular component organization GO:0051128 86 0.131
fourth ventricle development GO:0021592 8 0.130
appendage morphogenesis GO:0035107 56 0.130
Mouse
positive regulation of macromolecule metabolic process GO:0010604 93 0.129
cell death GO:0008219 121 0.129
cellular component assembly involved in morphogenesis GO:0010927 107 0.129
cell projection morphogenesis GO:0048858 244 0.128
positive regulation of cellular biosynthetic process GO:0031328 68 0.126
enzyme linked receptor protein signaling pathway GO:0007167 106 0.126
Mouse
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.126
embryonic foregut morphogenesis GO:0048617 1 0.126
regulation of bmp signaling pathway GO:0030510 39 0.126
Mouse
positive regulation of rna metabolic process GO:0051254 59 0.126
regulation of endodermal cell differentiation GO:1903224 15 0.125
regulation of cell cycle GO:0051726 52 0.125
mapk cascade GO:0000165 18 0.125
regulation of canonical wnt signaling pathway GO:0060828 34 0.122
regulation of catalytic activity GO:0050790 55 0.120
negative regulation of cellular biosynthetic process GO:0031327 55 0.120
Mouse
cell projection assembly GO:0030031 64 0.120
negative regulation of mesodermal cell fate specification GO:0042662 3 0.119
ectoderm development GO:0007398 9 0.116
protein phosphorylation GO:0006468 47 0.115
skin development GO:0043588 54 0.115
Mouse
regulation of molecular function GO:0065009 70 0.114
positive regulation of epithelial cell proliferation GO:0050679 1 0.113
regulation of stem cell proliferation GO:0072091 2 0.113
hindbrain morphogenesis GO:0021575 22 0.113
mesoderm development GO:0007498 88 0.112
Mouse
axial mesoderm formation GO:0048320 4 0.110
regulation of cell proliferation GO:0042127 37 0.110
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.109
neural plate morphogenesis GO:0001839 7 0.109
positive regulation of cell differentiation GO:0045597 30 0.109
Mouse
cell division GO:0051301 20 0.107
regulation of synapse assembly GO:0051963 3 0.105
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.104
Mouse
establishment of spindle localization GO:0051293 12 0.104
jnk cascade GO:0007254 7 0.104
epithelial tube morphogenesis GO:0060562 148 0.103
photoreceptor cell differentiation GO:0046530 55 0.103
negative regulation of apoptotic process GO:0043066 55 0.103
regulation of cytoplasmic transport GO:1903649 4 0.103
embryonic heart tube morphogenesis GO:0003143 108 0.102
retinal ganglion cell axon guidance GO:0031290 35 0.102
positive regulation of rna biosynthetic process GO:1902680 57 0.102
determination of left right asymmetry in nervous system GO:0035545 4 0.101
regulation of biological quality GO:0065008 263 0.101
kupffer s vesicle development GO:0070121 50 0.101
convergent extension GO:0060026 118 0.101
cerebellum development GO:0021549 17 0.101
negative regulation of rna metabolic process GO:0051253 48 0.100
Mouse
single organismal cell cell adhesion GO:0016337 29 0.099
regulation of protein complex assembly GO:0043254 3 0.099
homeostatic process GO:0042592 142 0.098
regulation of nervous system development GO:0051960 90 0.098
embryonic cranial skeleton morphogenesis GO:0048701 90 0.098
regulation of protein phosphorylation GO:0001932 18 0.098
establishment of localization in cell GO:0051649 77 0.098
epiboly GO:0090504 41 0.097
mesodermal cell migration GO:0008078 12 0.097
cartilage development GO:0051216 96 0.097
multi organism process GO:0051704 134 0.095
negative regulation of developmental process GO:0051093 65 0.095
Mouse
regulation of cell cycle process GO:0010564 20 0.094
regulation of cellular component movement GO:0051270 55 0.093
melanin metabolic process GO:0006582 2 0.093
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.093
oocyte maturation GO:0001556 4 0.093
fin development GO:0033333 77 0.092
developmental growth GO:0048589 166 0.091
regulation of mapk cascade GO:0043408 14 0.091
otic vesicle development GO:0071599 42 0.090
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.088
regulation of intracellular signal transduction GO:1902531 57 0.088
positive regulation of cellular metabolic process GO:0031325 94 0.088
regulation of protein catabolic process GO:0042176 1 0.088
positive regulation of nucleic acid templated transcription GO:1903508 57 0.087
endothelial cell development GO:0001885 12 0.087
single organism transport GO:0044765 206 0.087
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.086
negative regulation of cellular metabolic process GO:0031324 77 0.086
Mouse
floor plate formation GO:0021508 12 0.083
positive regulation of catabolic process GO:0009896 4 0.083
developmental induction GO:0031128 10 0.082
Mouse
regulation of cell cell adhesion GO:0022407 13 0.082
otic placode formation GO:0043049 23 0.081
regulation of kinase activity GO:0043549 15 0.081
cellular response to external stimulus GO:0071496 2 0.081
wnt signaling pathway GO:0016055 80 0.081
regulation of protein binding GO:0043393 3 0.080
gland morphogenesis GO:0022612 13 0.080
neural plate development GO:0001840 10 0.080
otic vesicle morphogenesis GO:0071600 34 0.080
negative regulation of cell death GO:0060548 60 0.080
synaptic growth at neuromuscular junction GO:0051124 2 0.080
positive regulation of muscle cell differentiation GO:0051149 1 0.079
embryonic neurocranium morphogenesis GO:0048702 15 0.079
posterior lateral line neuromast primordium migration GO:0048920 12 0.079
oocyte development GO:0048599 14 0.078
cardiogenic plate morphogenesis GO:0003142 1 0.078
positive regulation of map kinase activity GO:0043406 3 0.078
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.078
response to endogenous stimulus GO:0009719 83 0.077
regulation of locomotion GO:0040012 55 0.077
cellular localization GO:0051641 97 0.077
response to abiotic stimulus GO:0009628 122 0.076
cellular amino acid metabolic process GO:0006520 7 0.076
negative regulation of cell communication GO:0010648 96 0.076
secondary metabolic process GO:0019748 3 0.075
cilium morphogenesis GO:0060271 85 0.075
protein modification process GO:0036211 100 0.074
establishment of localization GO:0051234 244 0.074
cerebellum morphogenesis GO:0021587 10 0.074
nuclear transport GO:0051169 4 0.074
oligodendrocyte cell fate specification GO:0021778 4 0.073
regulation of phosphorylation GO:0042325 26 0.072
regulation of cell morphogenesis GO:0022604 42 0.072
stem cell differentiation GO:0048863 117 0.071
skeletal system development GO:0001501 181 0.071
negative regulation of programmed cell death GO:0043069 58 0.070
central nervous system segmentation GO:0035283 6 0.069
negative regulation of catabolic process GO:0009895 3 0.069
positive regulation of transport GO:0051050 2 0.068
nuclear import GO:0051170 3 0.068
regulation of cellular response to stress GO:0080135 20 0.068
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.067
Mouse
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.067
mesenchymal cell proliferation GO:0010463 1 0.067
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.067
negative regulation of gene expression GO:0010629 65 0.067
Mouse
embryonic heart tube left right pattern formation GO:0060971 5 0.066
positive regulation of cell proliferation GO:0008284 15 0.066
response to estradiol GO:0032355 6 0.066
programmed cell death GO:0012501 119 0.066
skeletal muscle organ development GO:0060538 78 0.065
Mouse
renal system development GO:0072001 94 0.064
gamete generation GO:0007276 33 0.064
angiogenesis GO:0001525 158 0.064
cellular component biogenesis GO:0044085 178 0.063
negative regulation of metabolic process GO:0009892 86 0.062
Mouse
cellular response to endogenous stimulus GO:0071495 68 0.062
regulation of apoptotic process GO:0042981 98 0.062
response to growth factor GO:0070848 39 0.061
specification of organ axis polarity GO:0010084 2 0.061
otic vesicle formation GO:0030916 27 0.060
organic substance transport GO:0071702 58 0.060
post anal tail morphogenesis GO:0036342 19 0.060
motor neuron axon guidance GO:0008045 23 0.060
regulation of oocyte development GO:0060281 3 0.060
regulation of mesodermal cell fate specification GO:0042661 9 0.059
negative regulation of phosphorus metabolic process GO:0010563 13 0.059
negative regulation of wnt signaling pathway GO:0030178 30 0.059
negative regulation of multicellular organismal process GO:0051241 69 0.059
Mouse
microtubule based process GO:0007017 60 0.058
formation of primary germ layer GO:0001704 62 0.058
Mouse
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.057
guanosine containing compound metabolic process GO:1901068 4 0.057
cellular ketone metabolic process GO:0042180 11 0.057
organelle localization GO:0051640 49 0.057
developmental process involved in reproduction GO:0003006 27 0.056

dkk1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.405
bone development disease DOID:0080006 0 0.093
bone disease DOID:0080001 0 0.093
musculoskeletal system disease DOID:17 0 0.093
connective tissue disease DOID:65 0 0.093