Danio rerio

0 known processes

dlg4

discs, large (Drosophila) homolog 4 and discs, large homolog 4 (Drosophila)

dlg4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
t cell cytokine production GO:0002369 1 0.513
vasculature development GO:0001944 278 0.437
blood vessel morphogenesis GO:0048514 216 0.298
regulation of cell matrix adhesion GO:0001952 1 0.209
regulation of metabolic process GO:0019222 359 0.198
Rat Fly
protein heterooligomerization GO:0051291 1 0.189
regulation of postsynaptic membrane potential GO:0060078 1 0.187
Rat
transmembrane transport GO:0055085 120 0.169
Rat
blood vessel development GO:0001568 246 0.158
response to stress GO:0006950 263 0.150
nucleic acid metabolic process GO:0090304 244 0.143
Fly
neuron development GO:0048666 262 0.142
Mouse Rat
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.137
ameboidal type cell migration GO:0001667 143 0.125
growth GO:0040007 174 0.124
Fly
monovalent inorganic cation transport GO:0015672 42 0.123
camera type eye development GO:0043010 222 0.122
regulation of protein complex assembly GO:0043254 3 0.113
larval development GO:0002164 2 0.113
Worm
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.104
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 11 0.104
cell matrix adhesion GO:0007160 4 0.101
regulation of metal ion transport GO:0010959 4 0.101
organic cyclic compound biosynthetic process GO:1901362 223 0.099
Fly
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.098
response to external stimulus GO:0009605 264 0.095
Fly
response to chemical GO:0042221 320 0.085
regulation of synaptic plasticity GO:0048167 1 0.083
Mouse
cell motility GO:0048870 244 0.081
autophagy GO:0006914 4 0.079
regulation of nucleic acid templated transcription GO:1903506 213 0.078
Fly
production of molecular mediator of immune response GO:0002440 2 0.075
negative regulation of biological process GO:0048519 304 0.074
Rat Fly
segmentation GO:0035282 97 0.073
Fly
neuron projection regeneration GO:0031102 16 0.073
organelle assembly GO:0070925 110 0.073
somitogenesis GO:0001756 87 0.072
heterocycle biosynthetic process GO:0018130 215 0.071
Fly
regulation of cytokine production GO:0001817 3 0.070
nucleic acid templated transcription GO:0097659 181 0.067
Fly
digestive system development GO:0055123 289 0.066
regulation of transcription dna templated GO:0006355 213 0.066
Fly
t cell mediated immunity GO:0002456 1 0.066
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.064
Mouse Rat
digestive tract development GO:0048565 265 0.064
heart development GO:0007507 313 0.064
signal transduction GO:0007165 455 0.064
Rat Fly
regulation of cell substrate adhesion GO:0010810 1 0.061
regionalization GO:0003002 274 0.060
Fly
medulla oblongata development GO:0021550 4 0.060
cytoskeleton organization GO:0007010 96 0.060
Fly
embryonic organ development GO:0048568 381 0.056
cell substrate adhesion GO:0031589 4 0.054
localization of cell GO:0051674 244 0.051
regulation of cellular amine metabolic process GO:0033238 0 0.051
aromatic compound biosynthetic process GO:0019438 217 0.050
Fly
polarized epithelial cell differentiation GO:0030859 4 0.049
rna metabolic process GO:0016070 219 0.049
Fly
synaptic growth at neuromuscular junction GO:0051124 2 0.048
Fly
somite development GO:0061053 96 0.048
chordate embryonic development GO:0043009 271 0.047
cellular amino acid metabolic process GO:0006520 7 0.046
establishment of localization GO:0051234 244 0.046
Human Mouse Rat Fly
regulation of biological quality GO:0065008 263 0.045
Mouse Rat Fly
tube morphogenesis GO:0035239 349 0.045
cell projection organization GO:0030030 284 0.045
Mouse Rat
positive regulation of biological process GO:0048518 253 0.044
Rat Fly
biosynthetic process GO:0009058 294 0.042
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.042
Worm
cortical cytoskeleton organization GO:0030865 1 0.042
organelle organization GO:0006996 227 0.041
Mouse Fly
renal system development GO:0072001 94 0.041
regulation of protein transport GO:0051223 3 0.041
cellular component biogenesis GO:0044085 178 0.041
Human Rat Worm Fly
chemosensory behavior GO:0007635 1 0.041
regulation of cellular amino acid metabolic process GO:0006521 0 0.040
transport GO:0006810 220 0.040
Mouse Rat
adherens junction organization GO:0034332 4 0.040
Worm
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.040
Fly
multi organism process GO:0051704 134 0.039
Mouse Worm Fly
cellular component morphogenesis GO:0032989 336 0.039
Mouse Rat
glucose import GO:0046323 2 0.039
morphogenesis of an epithelium GO:0002009 333 0.038
Fly
epithelial tube morphogenesis GO:0060562 148 0.037
retina development in camera type eye GO:0060041 146 0.037
angiogenesis GO:0001525 158 0.037
cortical actin cytoskeleton organization GO:0030866 1 0.037
regulation of multicellular organismal development GO:2000026 223 0.036
Fly
regulation of jak stat cascade GO:0046425 3 0.036
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.036
Fly
lymphocyte proliferation GO:0046651 1 0.036
anterior posterior pattern specification GO:0009952 152 0.035
Fly
protein localization to plasma membrane GO:0072659 1 0.035
cell migration GO:0016477 237 0.034
mononuclear cell proliferation GO:0032943 1 0.034
regulation of production of molecular mediator of immune response GO:0002700 1 0.034
inorganic cation transmembrane transport GO:0098662 50 0.034
regulation of multicellular organismal process GO:0051239 277 0.034
Fly
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.033
cytokine production involved in immune response GO:0002367 1 0.032
regulation of glucose transport GO:0010827 1 0.032
regulation of response to stimulus GO:0048583 269 0.032
Mouse Rat Fly
neurological system process GO:0050877 62 0.032
Mouse
positive regulation of cell adhesion GO:0045785 1 0.031
cell junction maintenance GO:0034331 2 0.031
positive regulation of developmental process GO:0051094 50 0.030
Fly
olfactory bulb development GO:0021772 4 0.030
regulation of cellular metabolic process GO:0031323 320 0.030
Rat Fly
cellular component assembly GO:0022607 170 0.030
Human Rat Worm Fly
cellular component movement GO:0006928 335 0.029
retina morphogenesis in camera type eye GO:0060042 79 0.029
female gonad development GO:0008585 4 0.029
rna biosynthetic process GO:0032774 181 0.029
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.028
Fly
potassium ion transport GO:0006813 10 0.028
heterocycle metabolic process GO:0046483 290 0.028
Fly
semicircular canal development GO:0060872 24 0.028
neuron projection development GO:0031175 180 0.028
Mouse Rat
regulation of meiotic cell cycle GO:0051445 1 0.027
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.027
regulation of synapse assembly GO:0051963 3 0.027
Fly
multicellular organism growth GO:0035264 4 0.027
ion transport GO:0006811 114 0.027
Rat
nuclear transport GO:0051169 4 0.026
positive regulation of cytokine production GO:0001819 2 0.026
regulation of mrna processing GO:0050684 3 0.026
cellular response to hormone stimulus GO:0032870 39 0.026
epidermis development GO:0008544 48 0.026
positive regulation of cytoskeleton organization GO:0051495 3 0.026
regulation of cellular ketone metabolic process GO:0010565 7 0.026
regulation of cellular component organization GO:0051128 86 0.026
Rat Fly
neuron projection morphogenesis GO:0048812 161 0.025
Mouse Rat
single organism transport GO:0044765 206 0.025
Mouse Rat
system process GO:0003008 185 0.025
Mouse
transmission of nerve impulse GO:0019226 19 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
Fly
phasic smooth muscle contraction GO:0014821 1 0.024
positive regulation of cellular process GO:0048522 201 0.024
Rat Fly
stem cell proliferation GO:0072089 4 0.024
biological adhesion GO:0022610 40 0.024
locomotor rhythm GO:0045475 3 0.024
Fly
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.023
axon regeneration GO:0031103 14 0.023
sensory organ morphogenesis GO:0090596 200 0.023
regulation of transmembrane transporter activity GO:0022898 2 0.023
Rat
single organism organelle organization GO:1902589 199 0.023
Mouse Fly
regulation of multicellular organism growth GO:0040014 4 0.023
mechanoreceptor differentiation GO:0042490 37 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
regulation of neurological system process GO:0031644 2 0.023
membrane hyperpolarization GO:0060081 1 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.022
Fly
positive regulation of catabolic process GO:0009896 4 0.022
protein localization to nucleus GO:0034504 3 0.022
regulation of macromolecule biosynthetic process GO:0010556 225 0.022
Fly
blood vessel endothelial cell migration GO:0043534 18 0.022
camera type eye morphogenesis GO:0048593 108 0.022
gastrulation GO:0007369 208 0.022
meiotic nuclear division GO:0007126 4 0.022
establishment of protein localization to organelle GO:0072594 4 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
Fly
glutamate receptor signaling pathway GO:0007215 1 0.022
Rat
hard palate development GO:0060022 4 0.022
compound eye development GO:0048749 2 0.022
protein polymerization GO:0051258 4 0.022
muscle tissue development GO:0060537 110 0.022
central nervous system development GO:0007417 387 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.021
Fly
organic substance biosynthetic process GO:1901576 289 0.021
Fly
regulation of rna metabolic process GO:0051252 224 0.021
Fly
lymphocyte mediated immunity GO:0002449 5 0.021
single organism behavior GO:0044708 24 0.021
Mouse Fly
phagocytosis GO:0006909 3 0.021
response to drug GO:0042493 3 0.021
aging GO:0007568 2 0.021
behavior GO:0007610 74 0.021
Mouse Fly
regulation of cellular biosynthetic process GO:0031326 245 0.020
Fly
organic acid metabolic process GO:0006082 31 0.020
insulin like growth factor receptor signaling pathway GO:0048009 4 0.020
regeneration GO:0031099 91 0.020
regulation of primary metabolic process GO:0080090 311 0.020
Fly
axonogenesis GO:0007409 152 0.020
macromolecule biosynthetic process GO:0009059 227 0.020
Fly
regulation of rna biosynthetic process GO:2001141 213 0.020
Fly
peptide transport GO:0015833 1 0.020
negative regulation of protein complex assembly GO:0031333 1 0.020
urogenital system development GO:0001655 97 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
epithelium migration GO:0090132 25 0.019
positive regulation of transport GO:0051050 2 0.019
muscle organ development GO:0007517 101 0.019
negative regulation of chemotaxis GO:0050922 4 0.019
protein secretion GO:0009306 1 0.019
cellular amine metabolic process GO:0044106 2 0.019
olfactory lobe development GO:0021988 4 0.019
response to light stimulus GO:0009416 46 0.019
Fly
cell surface receptor signaling pathway GO:0007166 325 0.019
Rat Fly
single organism nuclear import GO:1902593 3 0.019
regulation of ion transmembrane transporter activity GO:0032412 2 0.019
Rat
head development GO:0060322 303 0.019
cell cell recognition GO:0009988 1 0.019
nuclear import GO:0051170 3 0.019
regulation of localization GO:0032879 104 0.018
Rat
nitrogen compound metabolic process GO:0006807 319 0.018
Fly
positive regulation of cell activation GO:0050867 1 0.018
lens development in camera type eye GO:0002088 22 0.018
amine metabolic process GO:0009308 2 0.018
positive regulation of glucose import GO:0046326 1 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
macromolecular complex assembly GO:0065003 35 0.018
Human
response to other organism GO:0051707 97 0.018
neural crest cell development GO:0014032 62 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
Rat Fly
detection of stimulus GO:0051606 29 0.018
cellular ketone metabolic process GO:0042180 11 0.018
immune system development GO:0002520 191 0.018
cell part morphogenesis GO:0032990 246 0.018
Mouse Rat
female sex differentiation GO:0046660 4 0.017
mesenchyme development GO:0060485 127 0.017
regulation of biosynthetic process GO:0009889 250 0.017
Fly
membrane raft organization GO:0031579 1 0.017
skeletal muscle organ development GO:0060538 78 0.017
sensory organ development GO:0007423 393 0.017
regulation of phospholipase activity GO:0010517 2 0.017
pancreatic a cell development GO:0003322 2 0.017
positive regulation of immune effector process GO:0002699 3 0.017
regulation of glucose import GO:0046324 1 0.017
oxoacid metabolic process GO:0043436 31 0.017
neuroblast differentiation GO:0014016 1 0.017
motor neuron axon guidance GO:0008045 23 0.017
convergent extension GO:0060026 118 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
synapse organization GO:0050808 21 0.017
Rat Fly
leukocyte proliferation GO:0070661 1 0.016
cellular response to stress GO:0033554 62 0.016
maintenance of location GO:0051235 4 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
protein import into nucleus GO:0006606 3 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
steroid hormone secretion GO:0035929 1 0.016
intracellular signal transduction GO:0035556 85 0.016
Fly
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
amino acid transport GO:0006865 2 0.016
lipid storage GO:0019915 1 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
cell morphogenesis GO:0000902 289 0.016
Mouse Rat
organic substance transport GO:0071702 58 0.016
stem cell fate commitment GO:0048865 1 0.016
small molecule metabolic process GO:0044281 77 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
Fly
cardiocyte differentiation GO:0035051 44 0.015
macromolecular complex subunit organization GO:0043933 74 0.015
Human
adult behavior GO:0030534 2 0.015
nerve development GO:0021675 45 0.015
apical junction assembly GO:0043297 1 0.015
Worm
eye development GO:0001654 277 0.015
inner ear receptor cell differentiation GO:0060113 29 0.015
regulation of circadian rhythm GO:0042752 4 0.015
maternal determination of anterior posterior axis embryo GO:0008358 4 0.015
Fly
semicircular canal morphogenesis GO:0048752 18 0.015
regulation of membrane potential GO:0042391 23 0.015
Rat
protein metabolic process GO:0019538 183 0.015
establishment of protein localization to plasma membrane GO:0090002 1 0.015
cranial nerve development GO:0021545 42 0.015
regulation of reproductive process GO:2000241 4 0.015
maintenance of cell polarity GO:0030011 5 0.015
digestive tract mesoderm development GO:0007502 1 0.015
developmental growth GO:0048589 166 0.015
Fly
regulation of angiogenesis GO:0045765 26 0.015
meiotic cell cycle process GO:1903046 3 0.014
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.014
Fly
regulation of synapse organization GO:0050807 3 0.014
Fly
macromolecule localization GO:0033036 54 0.014
Human Mouse Rat Fly
sensory perception of chemical stimulus GO:0007606 3 0.014
regulation of cell activation GO:0050865 1 0.014
protein import GO:0017038 3 0.014
cellular component maintenance GO:0043954 3 0.014
microtubule cytoskeleton organization GO:0000226 33 0.014
Fly
endocardium morphogenesis GO:0003160 4 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
Fly
positive regulation of metabolic process GO:0009893 108 0.014
optic nerve development GO:0021554 15 0.014
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.014
locomotion GO:0040011 313 0.014
Fly
pancreatic d cell differentiation GO:0003311 2 0.014
dorsal ventral pattern formation GO:0009953 125 0.014
positive regulation of leukocyte mediated immunity GO:0002705 1 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
response to external biotic stimulus GO:0043207 97 0.013
neural crest cell migration GO:0001755 42 0.013
peptidyl serine modification GO:0018209 2 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
positive regulation of synapse assembly GO:0051965 1 0.013
Fly
response to organic substance GO:0010033 153 0.013
organic cyclic compound metabolic process GO:1901360 301 0.013
Fly
cell projection morphogenesis GO:0048858 244 0.013
Mouse Rat
brain development GO:0007420 293 0.013
response to abiotic stimulus GO:0009628 122 0.013
Fly
regulation of protein polymerization GO:0032271 2 0.013
response to biotic stimulus GO:0009607 97 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
regulation of lipase activity GO:0060191 2 0.013
ion transmembrane transport GO:0034220 91 0.013
Rat
cellular response to toxic substance GO:0097237 1 0.013
nephron development GO:0072006 31 0.013
positive regulation of glucose transport GO:0010828 1 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
embryonic heart tube development GO:0035050 133 0.012
cellular response to oxygen containing compound GO:1901701 20 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
forebrain cell migration GO:0021885 1 0.012
establishment of epithelial cell polarity GO:0090162 2 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
axial mesoderm development GO:0048318 10 0.012
morphogenesis of follicular epithelium GO:0016333 1 0.012
Fly
negative regulation of cellular process GO:0048523 283 0.012
Rat Fly
cell cell junction maintenance GO:0045217 1 0.012
negative regulation of rna biosynthetic process GO:1902679 45 0.012
Fly
regulation of locomotion GO:0040012 55 0.012
phosphorus metabolic process GO:0006793 109 0.012
tissue regeneration GO:0042246 74 0.012
mrna 3 end processing GO:0031124 2 0.012
specification of organ identity GO:0010092 2 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
peripheral nervous system neuron development GO:0048935 22 0.012
cell migration involved in gastrulation GO:0042074 79 0.012
positive regulation of protein polymerization GO:0032273 2 0.012
septum transversum development GO:0003343 4 0.012
endoderm development GO:0007492 49 0.012
guanosine containing compound catabolic process GO:1901069 2 0.011
embryonic hemopoiesis GO:0035162 53 0.011
mesenchymal cell development GO:0014031 78 0.011
regulation of hydrolase activity GO:0051336 28 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
phosphorylation GO:0016310 69 0.011
cellular macromolecule metabolic process GO:0044260 391 0.011
Rat Fly
response to alkaloid GO:0043279 2 0.011
axon ensheathment in central nervous system GO:0032291 2 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
calcium mediated signaling GO:0019722 2 0.011
negative regulation of defense response GO:0031348 2 0.011
establishment or maintenance of bipolar cell polarity GO:0061245 12 0.011
regulation of cellular ph GO:0030641 1 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
muscle cell development GO:0055001 115 0.011
regulation of anatomical structure size GO:0090066 33 0.011
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.011
post embryonic morphogenesis GO:0009886 4 0.011
cell cycle arrest GO:0007050 1 0.011
regulation of receptor activity GO:0010469 2 0.011
Rat
mesoderm development GO:0007498 88 0.011
ear development GO:0043583 127 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
pronephros development GO:0048793 69 0.011
hormone transport GO:0009914 2 0.011
regulation of cytoskeleton organization GO:0051493 11 0.011
regulation of cell adhesion GO:0030155 15 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
Fly
regulation of transporter activity GO:0032409 2 0.011
Rat
axon extension GO:0048675 45 0.011
maintenance of epithelial cell apical basal polarity GO:0045199 5 0.011
actin filament based process GO:0030029 64 0.011
regulation of wnt signaling pathway GO:0030111 53 0.011
regulation of protein import into nucleus GO:0042306 2 0.010
guanosine containing compound metabolic process GO:1901068 4 0.010
actin cytoskeleton organization GO:0030036 63 0.010
regulation of programmed cell death GO:0043067 101 0.010
nephron tubule morphogenesis GO:0072078 1 0.010
gene expression GO:0010467 252 0.010
Fly
heart morphogenesis GO:0003007 156 0.010
enzyme linked receptor protein signaling pathway GO:0007167 106 0.010
Fly
blood circulation GO:0008015 87 0.010
regulation of growth rate GO:0040009 1 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
generation of neurons GO:0048699 385 0.010
Mouse Rat
protein complex subunit organization GO:0071822 46 0.010
Human
synaptic transmission GO:0007268 35 0.010
Mouse Rat Fly
endocardium formation GO:0060214 1 0.010
regulation of nucleoside metabolic process GO:0009118 2 0.010
regulation of leukocyte mediated immunity GO:0002703 1 0.010
regulation of catalytic activity GO:0050790 55 0.010

dlg4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.143
nervous system disease DOID:863 0 0.024