Danio rerio

104 known processes

dll4

delta-like 4 (Drosophila)

(Aliases: zgc:136596,si:ch211-244p18.5)

dll4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vasculature development GO:0001944 278 0.994
sprouting angiogenesis GO:0002040 53 0.989
blood vessel morphogenesis GO:0048514 216 0.985
blood vessel development GO:0001568 246 0.967
angiogenesis GO:0001525 158 0.758
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.749
venous blood vessel development GO:0060841 9 0.649
ameboidal type cell migration GO:0001667 143 0.624
embryonic organ development GO:0048568 381 0.599
Zebrafish
blood vessel endothelial cell migration GO:0043534 18 0.597
hematopoietic or lymphoid organ development GO:0048534 191 0.593
Zebrafish
vasculogenesis GO:0001570 41 0.547
epithelial cell migration GO:0010631 25 0.522
endothelial cell migration GO:0043542 19 0.500
morphogenesis of an epithelium GO:0002009 333 0.500
endothelium development GO:0003158 25 0.496
Mouse
regulation of multicellular organismal process GO:0051239 277 0.486
generation of neurons GO:0048699 385 0.475
Human Zebrafish Mouse Fly
epithelial cell development GO:0002064 42 0.413
Zebrafish Fly
tube morphogenesis GO:0035239 349 0.404
branching morphogenesis of an epithelial tube GO:0048754 15 0.395
aromatic compound biosynthetic process GO:0019438 217 0.384
Mouse
regulation of retina development in camera type eye GO:1902866 2 0.375
Mouse
locomotion GO:0040011 313 0.372
negative regulation of biological process GO:0048519 304 0.366
regulation of angiogenesis GO:0045765 26 0.337
morphogenesis of a branching epithelium GO:0061138 16 0.332
cellular component morphogenesis GO:0032989 336 0.332
Zebrafish Fly
epithelial cell differentiation GO:0030855 116 0.330
Zebrafish Fly
patterning of blood vessels GO:0001569 15 0.295
response to external biotic stimulus GO:0043207 97 0.286
cell motility GO:0048870 244 0.282
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.259
Mouse
neuron differentiation GO:0030182 353 0.253
Human Zebrafish
osteoclast development GO:0036035 1 0.238
embryonic organ morphogenesis GO:0048562 274 0.228
Zebrafish
cellular component assembly GO:0022607 170 0.218
Zebrafish
positive regulation of cell matrix adhesion GO:0001954 1 0.216
signal transduction GO:0007165 455 0.211
venous blood vessel morphogenesis GO:0048845 3 0.206
stem cell development GO:0048864 82 0.205
Zebrafish Fly
regulation of cellular metabolic process GO:0031323 320 0.204
Mouse
endothelial cell development GO:0001885 12 0.196
tissue migration GO:0090130 37 0.193
heart contraction GO:0060047 71 0.192
regulation of signal transduction GO:0009966 225 0.190
regulation of vasculature development GO:1901342 33 0.188
regulation of multicellular organismal development GO:2000026 223 0.181
nitrogen compound metabolic process GO:0006807 319 0.180
Mouse
digestive tract development GO:0048565 265 0.173
Zebrafish
sensory organ development GO:0007423 393 0.168
Zebrafish Mouse Fly
lymph vessel morphogenesis GO:0036303 25 0.167
localization of cell GO:0051674 244 0.161
macrophage chemotaxis GO:0048246 3 0.160
i kappab kinase nf kappab signaling GO:0007249 4 0.158
endothelial cell differentiation GO:0045446 20 0.158
organic substance biosynthetic process GO:1901576 289 0.158
Mouse
regulation of heart contraction GO:0008016 32 0.153
neuron development GO:0048666 262 0.152
Zebrafish
xanthophore differentiation GO:0050936 3 0.150
immune system process GO:0002376 241 0.148
Zebrafish
cell morphogenesis GO:0000902 289 0.141
Zebrafish Fly
blood vessel endothelial cell differentiation GO:0060837 2 0.140
eye development GO:0001654 277 0.140
Mouse Fly
cellular biosynthetic process GO:0044249 286 0.139
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.137
Mouse
biosynthetic process GO:0009058 294 0.137
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.135
Mouse
pericardium development GO:0060039 1 0.134
Mouse
regulation of neural retina development GO:0061074 2 0.128
Mouse
gland development GO:0048732 143 0.128
Zebrafish
positive regulation of macrophage chemotaxis GO:0010759 1 0.126
epithelial tube morphogenesis GO:0060562 148 0.122
lymphangiogenesis GO:0001946 25 0.121
regulation of organ growth GO:0046620 3 0.121
regulation of metal ion transport GO:0010959 4 0.120
developmental pigmentation GO:0048066 48 0.117
microglia differentiation GO:0014004 1 0.116
antimicrobial humoral response GO:0019730 2 0.112
regulation of endothelial cell proliferation GO:0001936 1 0.109
meiotic nuclear division GO:0007126 4 0.108
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.108
Human
positive regulation of cell differentiation GO:0045597 30 0.107
negative regulation of cellular process GO:0048523 283 0.106
hematopoietic stem cell differentiation GO:0060218 20 0.106
Zebrafish
skeletal system development GO:0001501 181 0.104
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.103
Mouse
response to hypoxia GO:0001666 25 0.103
myeloid cell differentiation GO:0030099 86 0.101
regulation of cell communication GO:0010646 232 0.101
negative regulation of angiogenesis GO:0016525 7 0.101
Human
hemopoiesis GO:0030097 183 0.099
Zebrafish
system process GO:0003008 185 0.097
larval development GO:0002164 2 0.097
cell migration GO:0016477 237 0.097
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.096
cardiac atrium morphogenesis GO:0003209 2 0.095
Mouse
cellular response to endogenous stimulus GO:0071495 68 0.094
Human
negative regulation of epithelial cell migration GO:0010633 1 0.090
response to decreased oxygen levels GO:0036293 25 0.090
organelle organization GO:0006996 227 0.090
Zebrafish Fly
artery development GO:0060840 22 0.089
cellular response to chemical stimulus GO:0070887 157 0.088
cellular macromolecule biosynthetic process GO:0034645 224 0.087
Mouse
rna biosynthetic process GO:0032774 181 0.087
Mouse
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 0.087
regulation of reactive oxygen species metabolic process GO:2000377 2 0.087
regulation of protein targeting GO:1903533 2 0.086
response to chemical GO:0042221 320 0.084
granulocyte chemotaxis GO:0071621 11 0.082
muscle structure development GO:0061061 196 0.082
Mouse
smooth muscle contraction GO:0006939 2 0.080
melanocyte migration GO:0097324 4 0.079
tissue remodeling GO:0048771 4 0.079
Mouse
positive regulation of endothelial cell proliferation GO:0001938 1 0.078
heart development GO:0007507 313 0.078
Mouse
response to oxygen levels GO:0070482 25 0.077
connective tissue development GO:0061448 99 0.076
Zebrafish
regulation of epithelial cell proliferation GO:0050678 3 0.076
heterocycle biosynthetic process GO:0018130 215 0.074
Mouse
positive regulation of signal transduction GO:0009967 56 0.072
regulation of biological quality GO:0065008 263 0.072
growth GO:0040007 174 0.072
regulation of rna metabolic process GO:0051252 224 0.071
Mouse
positive regulation of cellular process GO:0048522 201 0.071
Mouse Fly
cell migration involved in sprouting angiogenesis GO:0002042 8 0.070
Human
regulation of establishment of protein localization GO:0070201 4 0.070
pigmentation GO:0043473 85 0.070
response to abiotic stimulus GO:0009628 122 0.068
lateral line system development GO:0048925 76 0.068
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.068
regulation of cell death GO:0010941 103 0.068
embryonic heart tube development GO:0035050 133 0.068
developmental programmed cell death GO:0010623 4 0.067
stem cell differentiation GO:0048863 117 0.066
Zebrafish Fly
leukocyte differentiation GO:0002521 25 0.066
regulation of response to stimulus GO:0048583 269 0.066
endocardium development GO:0003157 9 0.065
immune response GO:0006955 28 0.065
developmental growth GO:0048589 166 0.065
regulation of nucleocytoplasmic transport GO:0046822 2 0.064
brain development GO:0007420 293 0.064
Zebrafish
cytoskeleton organization GO:0007010 96 0.063
Fly
thyroid gland development GO:0030878 12 0.063
Zebrafish
regulation of gene expression GO:0010468 265 0.063
Mouse
circulatory system process GO:0003013 87 0.063
aging GO:0007568 2 0.062
gliogenesis GO:0042063 45 0.061
Fly
protein import into nucleus GO:0006606 3 0.061
digestive tract morphogenesis GO:0048546 231 0.061
Zebrafish
regulation of intracellular signal transduction GO:1902531 57 0.060
embryonic viscerocranium morphogenesis GO:0048703 52 0.060
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.059
sensory system development GO:0048880 76 0.059
transmission of nerve impulse GO:0019226 19 0.059
positive regulation of leukocyte migration GO:0002687 2 0.058
mononuclear cell migration GO:0071674 1 0.058
neuronal action potential GO:0019228 18 0.058
regulation of cellular biosynthetic process GO:0031326 245 0.057
Mouse
t cell activation GO:0042110 6 0.056
oxidation reduction process GO:0055114 41 0.055
cell cycle GO:0007049 93 0.055
Fly
skeletal muscle organ development GO:0060538 78 0.055
response to mechanical stimulus GO:0009612 24 0.055
regulation of cytoplasmic transport GO:1903649 4 0.054
amine metabolic process GO:0009308 2 0.054
cell projection assembly GO:0030031 64 0.054
Zebrafish
response to stress GO:0006950 263 0.053
neuromast development GO:0048884 46 0.053
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.053
regulation of binding GO:0051098 3 0.053
positive regulation of leukocyte chemotaxis GO:0002690 1 0.053
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.053
stem cell maintenance GO:0019827 4 0.052
Fly
establishment of localization GO:0051234 244 0.052
mononuclear cell proliferation GO:0032943 1 0.051
cell migration involved in heart development GO:0060973 22 0.050
positive regulation of rna metabolic process GO:0051254 59 0.050
eye morphogenesis GO:0048592 144 0.050
Fly
regulation of apoptotic process GO:0042981 98 0.050
organic cyclic compound metabolic process GO:1901360 301 0.050
Mouse
apoptotic process GO:0006915 116 0.049
positive regulation of neural retina development GO:0061075 1 0.049
central nervous system development GO:0007417 387 0.049
Human Zebrafish
nucleobase containing compound biosynthetic process GO:0034654 205 0.049
Mouse
regulation of protein transport GO:0051223 3 0.048
chordate embryonic development GO:0043009 271 0.048
Zebrafish
regulation of anatomical structure morphogenesis GO:0022603 130 0.048
transport GO:0006810 220 0.048
enzyme linked receptor protein signaling pathway GO:0007167 106 0.048
spinal cord motor neuron differentiation GO:0021522 26 0.047
Zebrafish
inner ear receptor cell differentiation GO:0060113 29 0.047
Zebrafish
regulation of biosynthetic process GO:0009889 250 0.046
Mouse
skeletal muscle tissue development GO:0007519 67 0.046
regulation of protein complex assembly GO:0043254 3 0.046
tissue regeneration GO:0042246 74 0.046
negative regulation of apoptotic process GO:0043066 55 0.046
positive regulation of protein kinase b signaling GO:0051897 1 0.046
protein complex localization GO:0031503 1 0.045
stem cell proliferation GO:0072089 4 0.045
cellular response to organic substance GO:0071310 105 0.045
cell substrate adhesion GO:0031589 4 0.045
cellular lipid metabolic process GO:0044255 36 0.044
cellular nitrogen compound metabolic process GO:0034641 290 0.044
Mouse
positive regulation of immune system process GO:0002684 17 0.044
regulation of metabolic process GO:0019222 359 0.044
Mouse
regulation of dna replication GO:0006275 3 0.044
positive regulation of developmental process GO:0051094 50 0.043
small molecule metabolic process GO:0044281 77 0.043
hepaticobiliary system development GO:0061008 98 0.043
Zebrafish
negative regulation of cell motility GO:2000146 17 0.043
epithelium migration GO:0090132 25 0.042
regulation of mononuclear cell migration GO:0071675 1 0.042
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.042
chemotaxis GO:0006935 104 0.042
positive regulation of map kinase activity GO:0043406 3 0.042
notch signaling pathway GO:0007219 35 0.041
Zebrafish Mouse Fly
immune system development GO:0002520 191 0.041
Zebrafish
regulation of cell proliferation GO:0042127 37 0.041
Human Mouse Fly
protein targeting to nucleus GO:0044744 3 0.041
ion transport GO:0006811 114 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.041
Mouse
fat soluble vitamin metabolic process GO:0006775 4 0.041
regulation of cell matrix adhesion GO:0001952 1 0.041
positive regulation of cellular component biogenesis GO:0044089 3 0.041
cell surface receptor signaling pathway GO:0007166 325 0.041
regulation of glial cell differentiation GO:0045685 4 0.041
odontogenesis of dentin containing tooth GO:0042475 1 0.040
pigment cell differentiation GO:0050931 38 0.040
positive regulation of catabolic process GO:0009896 4 0.040
exocytosis GO:0006887 1 0.040
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.039
germ line stem cell maintenance GO:0030718 2 0.039
Fly
lateral line development GO:0048882 66 0.039
transcription dna templated GO:0006351 181 0.039
Mouse
cellular response to external stimulus GO:0071496 2 0.039
regulation of epithelial cell migration GO:0010632 5 0.039
peptide transport GO:0015833 1 0.039
negative regulation of epithelial cell proliferation GO:0050680 1 0.038
regulation of cell motility GO:2000145 46 0.038
mechanosensory behavior GO:0007638 2 0.038
striated muscle cell differentiation GO:0051146 129 0.038
cell death GO:0008219 121 0.038
protein complex subunit organization GO:0071822 46 0.038
Fly
macromolecule biosynthetic process GO:0009059 227 0.037
Mouse
cartilage development GO:0051216 96 0.037
Zebrafish
negative regulation of protein complex assembly GO:0031333 1 0.037
regulation of nucleic acid templated transcription GO:1903506 213 0.037
Mouse
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.036
negative regulation of signal transduction GO:0009968 94 0.036
neural crest cell differentiation GO:0014033 72 0.036
Zebrafish
single organism localization GO:1902578 225 0.036
positive regulation of transport GO:0051050 2 0.035
peptidyl serine phosphorylation GO:0018105 1 0.035
regulation of cell migration GO:0030334 40 0.035
cell proliferation GO:0008283 80 0.035
regulation of protein import into nucleus GO:0042306 2 0.035
endocrine system development GO:0035270 65 0.035
Zebrafish
mesenchyme development GO:0060485 127 0.034
Zebrafish
neuroepithelial cell differentiation GO:0060563 26 0.034
single organism organelle organization GO:1902589 199 0.034
Zebrafish Fly
morphogenesis of a branching structure GO:0001763 21 0.034
camera type eye development GO:0043010 222 0.034
Mouse
artery morphogenesis GO:0048844 14 0.034
Mouse
blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 4 0.034
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.034
death GO:0016265 121 0.034
regulation of cell shape GO:0008360 1 0.034
cognition GO:0050890 1 0.033
response to hormone GO:0009725 48 0.033
myeloid cell homeostasis GO:0002262 56 0.033
cellular response to molecule of bacterial origin GO:0071219 3 0.033
biological adhesion GO:0022610 40 0.033
establishment of protein localization to organelle GO:0072594 4 0.033
response to light stimulus GO:0009416 46 0.033
neural retina development GO:0003407 49 0.033
Mouse
cellular ketone metabolic process GO:0042180 11 0.033
segmentation GO:0035282 97 0.033
Zebrafish Fly
regeneration GO:0031099 91 0.033
specification of symmetry GO:0009799 204 0.033
Zebrafish
negative regulation of cell migration GO:0030336 17 0.032
regulation of meiotic cell cycle GO:0051445 1 0.032
regulation of nitrogen compound metabolic process GO:0051171 251 0.032
Mouse
negative regulation of programmed cell death GO:0043069 58 0.032
cation transport GO:0006812 81 0.032
protein import GO:0017038 3 0.032
regulation of protein localization to nucleus GO:1900180 2 0.032
heart morphogenesis GO:0003007 156 0.032
Mouse
regulation of programmed cell death GO:0043067 101 0.032
programmed cell death GO:0012501 119 0.032
positive regulation of response to stimulus GO:0048584 80 0.031
heart process GO:0003015 71 0.031
embryonic heart tube morphogenesis GO:0003143 108 0.031
regulation of cytokine production GO:0001817 3 0.031
regulation of neurogenesis GO:0050767 87 0.031
Mouse Fly
neuron projection morphogenesis GO:0048812 161 0.031
neuroblast proliferation GO:0007405 2 0.031
cilium morphogenesis GO:0060271 85 0.031
Zebrafish
phosphorylation GO:0016310 69 0.031
mechanosensory lateral line system development GO:0048881 49 0.031
nucleic acid metabolic process GO:0090304 244 0.030
Mouse
glial cell differentiation GO:0010001 42 0.030
cellular response to lipopolysaccharide GO:0071222 3 0.030
muscle system process GO:0003012 20 0.030
cellular component movement GO:0006928 335 0.030
regulation of bmp signaling pathway GO:0030510 39 0.030
regulation of intracellular protein transport GO:0033157 3 0.030
regulation of protein metabolic process GO:0051246 56 0.030
axon development GO:0061564 166 0.030
determination of heart left right asymmetry GO:0061371 117 0.030
regulation of macromolecule metabolic process GO:0060255 317 0.030
Mouse
striated muscle tissue development GO:0014706 110 0.030
Mouse
oxoacid metabolic process GO:0043436 31 0.029
wound healing GO:0042060 90 0.029
granulocyte migration GO:0097530 11 0.029
leukocyte proliferation GO:0070661 1 0.029
cell substrate junction assembly GO:0007044 2 0.029
dorsal aorta development GO:0035907 4 0.029
Mouse
protein metabolic process GO:0019538 183 0.029
single organism nuclear import GO:1902593 3 0.029
epidermal cell differentiation GO:0009913 36 0.029
Zebrafish
gene expression GO:0010467 252 0.029
Mouse
regulation of cell activation GO:0050865 1 0.028
regulation of transport GO:0051049 45 0.028
regulation of dendrite development GO:0050773 3 0.028
regulation of heart growth GO:0060420 2 0.028
hematopoietic progenitor cell differentiation GO:0002244 23 0.028
Zebrafish
blood circulation GO:0008015 87 0.028
regulation of cellular response to growth factor stimulus GO:0090287 35 0.028
cellular component biogenesis GO:0044085 178 0.028
Zebrafish
cardiac conduction system development GO:0003161 1 0.028
response to external stimulus GO:0009605 264 0.028
positive regulation of phospholipase c activity GO:0010863 1 0.028
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.027
cellular response to vascular endothelial growth factor stimulus GO:0035924 3 0.027
Human
epidermal cell fate specification GO:0009957 4 0.027
nucleocytoplasmic transport GO:0006913 4 0.027
gastrulation GO:0007369 208 0.027
negative regulation of cell death GO:0060548 60 0.027
regulation of neuron differentiation GO:0045664 56 0.027
lymph vessel development GO:0001945 27 0.027
heterocycle metabolic process GO:0046483 290 0.027
Mouse
ovarian follicle development GO:0001541 2 0.027
regulation of endothelial cell differentiation GO:0045601 3 0.027
neuron projection development GO:0031175 180 0.027
macromolecular complex subunit organization GO:0043933 74 0.026
Fly
positive regulation of retina development in camera type eye GO:1902868 1 0.026
cellular aromatic compound metabolic process GO:0006725 295 0.026
Mouse
regulation of macrophage chemotaxis GO:0010758 1 0.026
regulation of oligodendrocyte differentiation GO:0048713 1 0.026
endocardium morphogenesis GO:0003160 4 0.026
anatomical structure homeostasis GO:0060249 36 0.026
pericardium morphogenesis GO:0003344 1 0.026
Mouse
mesoderm development GO:0007498 88 0.026
Zebrafish Fly
positive regulation of cell cycle GO:0045787 3 0.026
Fly
regulation of immune system process GO:0002682 34 0.026
maintenance of location GO:0051235 4 0.025
response to drug GO:0042493 3 0.025
muscle cell differentiation GO:0042692 139 0.025
lateral inhibition GO:0046331 1 0.025
Zebrafish Fly
meiosis ii GO:0007135 1 0.025
positive regulation of intracellular signal transduction GO:1902533 15 0.025
atp catabolic process GO:0006200 4 0.025
organism emergence from protective structure GO:0071684 4 0.025
multicellular organismal signaling GO:0035637 22 0.025
neural crest cell migration GO:0001755 42 0.025
guanosine containing compound metabolic process GO:1901068 4 0.025
actomyosin structure organization GO:0031032 53 0.025
cation transmembrane transport GO:0098655 65 0.025
regulation of erk1 and erk2 cascade GO:0070372 4 0.024
positive regulation of cell communication GO:0010647 56 0.024
behavior GO:0007610 74 0.024
neurological system process GO:0050877 62 0.024
cellular response to extracellular stimulus GO:0031668 2 0.024
regulation of primary metabolic process GO:0080090 311 0.024
Mouse
negative regulation of gliogenesis GO:0014014 1 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
nucleic acid templated transcription GO:0097659 181 0.024
Mouse
positive regulation of nervous system development GO:0051962 25 0.023
embryo development ending in birth or egg hatching GO:0009792 271 0.023
Zebrafish
neural tube development GO:0021915 62 0.023
Zebrafish
cell projection organization GO:0030030 284 0.023
Zebrafish
cardiac atrium development GO:0003230 4 0.023
Mouse
cellular response to hormone stimulus GO:0032870 39 0.023
cell matrix adhesion GO:0007160 4 0.023
homeostatic process GO:0042592 142 0.023
nucleoside monophosphate catabolic process GO:0009125 4 0.023
arterial endothelial cell differentiation GO:0060842 2 0.023
leukocyte chemotaxis GO:0030595 12 0.023
regulation of vasculogenesis GO:2001212 1 0.023
retina development in camera type eye GO:0060041 146 0.023
Mouse
regulation of circadian rhythm GO:0042752 4 0.023
convergent extension GO:0060026 118 0.023
regulation of sodium ion transport GO:0002028 2 0.023
response to hydrogen peroxide GO:0042542 3 0.022
positive regulation of metabolic process GO:0009893 108 0.022
ear development GO:0043583 127 0.022
Zebrafish
embryonic skeletal system development GO:0048706 97 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.022
Mouse
defense response to fungus GO:0050832 2 0.022
regulation of dendrite morphogenesis GO:0048814 3 0.022
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.022
Zebrafish
phosphorus metabolic process GO:0006793 109 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
Mouse
neurotransmitter secretion GO:0007269 2 0.022
astral microtubule organization GO:0030953 1 0.022
inner ear development GO:0048839 126 0.022
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 195 0.022
Fly
regulation of phosphorylation GO:0042325 26 0.022
muscle contraction GO:0006936 18 0.022
cell type specific apoptotic process GO:0097285 22 0.021
transcription from rna polymerase ii promoter GO:0006366 80 0.021
Mouse
regulation of leukocyte migration GO:0002685 8 0.021
ribonucleoside monophosphate catabolic process GO:0009158 4 0.021
urogenital system development GO:0001655 97 0.021
Zebrafish
regulation of developmental process GO:0050793 247 0.021
anterior posterior pattern specification GO:0009952 152 0.021
Zebrafish
regulation of skeletal muscle fiber development GO:0048742 2 0.021
muscle tissue development GO:0060537 110 0.021
Mouse
ion transmembrane transport GO:0034220 91 0.021
tissue homeostasis GO:0001894 25 0.020
regulation of system process GO:0044057 40 0.020
t cell differentiation GO:0030217 6 0.020
positive regulation of biosynthetic process GO:0009891 68 0.020
muscle organ development GO:0007517 101 0.020
Mouse
b cell activation GO:0042113 2 0.020
aorta development GO:0035904 4 0.020
Mouse
cellular response to nutrient levels GO:0031669 2 0.020
determination of left right symmetry GO:0007368 179 0.020
Zebrafish
spinal cord development GO:0021510 46 0.019
Human Zebrafish
positive regulation of cellular metabolic process GO:0031325 94 0.019
apoptotic process involved in morphogenesis GO:0060561 2 0.019
negative regulation of blood vessel morphogenesis GO:2000181 8 0.019
Human
negative regulation of cell differentiation GO:0045596 46 0.019
Fly
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.019
Fly
endothelial cell morphogenesis GO:0001886 1 0.019
regulation of nervous system development GO:0051960 90 0.019
Mouse Fly
embryonic hemopoiesis GO:0035162 53 0.019
protein secretion GO:0009306 1 0.019
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.019
cellular amine metabolic process GO:0044106 2 0.019
ventricular cardiac muscle tissue development GO:0003229 3 0.019
Mouse
negative regulation of protein kinase activity GO:0006469 4 0.019
positive regulation of stem cell proliferation GO:2000648 1 0.019
negative regulation of cell communication GO:0010648 96 0.019
heart looping GO:0001947 94 0.019
xenobiotic metabolic process GO:0006805 4 0.019
establishment of localization in cell GO:0051649 77 0.019
regulation of granulocyte chemotaxis GO:0071622 6 0.019
metal ion transport GO:0030001 58 0.019
myelination GO:0042552 18 0.018
macromolecule modification GO:0043412 111 0.018
homeostasis of number of cells GO:0048872 62 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
positive regulation of cytokine production GO:0001819 2 0.018
neural crest cell development GO:0014032 62 0.018
Zebrafish
regulation of reproductive process GO:2000241 4 0.018
response to antibiotic GO:0046677 1 0.018
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
nuclear import GO:0051170 3 0.018
regulation of establishment of cell polarity GO:2000114 1 0.018
multicellular organism growth GO:0035264 4 0.018
single organism metabolic process GO:0044710 217 0.018
homeostasis of number of cells within a tissue GO:0048873 4 0.018
reproduction GO:0000003 40 0.018
Fly
cell fate commitment GO:0045165 99 0.018
Human Zebrafish Fly
striated muscle cell development GO:0055002 108 0.018
regulation of myotube differentiation GO:0010830 2 0.018
coenzyme biosynthetic process GO:0009108 2 0.017
osteoclast differentiation GO:0030316 1 0.017
lateral mesoderm development GO:0048368 23 0.017
Zebrafish
epidermis development GO:0008544 48 0.017
Zebrafish
endothelial cell proliferation GO:0001935 11 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.017
Mouse
erythrocyte homeostasis GO:0034101 55 0.017
bmp signaling pathway GO:0030509 52 0.017
cell part morphogenesis GO:0032990 246 0.017
Zebrafish
cellular protein catabolic process GO:0044257 4 0.017
response to biotic stimulus GO:0009607 97 0.017
response to oxygen containing compound GO:1901700 55 0.017
melanocyte apoptotic process GO:1902362 2 0.017
glial cell proliferation GO:0014009 4 0.017
regulation of molecular function GO:0065009 70 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
spindle assembly GO:0051225 2 0.017
lymphocyte proliferation GO:0046651 1 0.017
rhombomere 5 development GO:0021571 4 0.017
positive regulation of cell activation GO:0050867 1 0.017
cell cycle process GO:0022402 53 0.017
axonogenesis GO:0007409 152 0.017
mesenchymal cell proliferation GO:0010463 1 0.017
regulation of blood vessel endothelial cell migration GO:0043535 5 0.017

dll4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.091
immune system disease DOID:2914 0 0.032
hematopoietic system disease DOID:74 0 0.032