Danio rerio

0 known processes

dlst

dihydrolipoamide S-succinyltransferase

(Aliases: cb60,wu:fc39d01)

dlst biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.802
Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.623
Worm
pyruvate metabolic process GO:0006090 1 0.466
mitochondrial atp synthesis coupled electron transport GO:0042775 1 0.406
coenzyme biosynthetic process GO:0009108 2 0.356
atp synthesis coupled electron transport GO:0042773 1 0.353
organic acid catabolic process GO:0016054 3 0.317
aging GO:0007568 2 0.285
carboxylic acid catabolic process GO:0046395 3 0.268
electron transport chain GO:0022900 2 0.264
cellular respiration GO:0045333 3 0.237
thioester biosynthetic process GO:0035384 1 0.207
nucleobase containing compound metabolic process GO:0006139 274 0.190
regionalization GO:0003002 274 0.173
oxidative phosphorylation GO:0006119 1 0.158
single organism metabolic process GO:0044710 217 0.153
Yeast
developmental growth GO:0048589 166 0.149
multicellular organism growth GO:0035264 4 0.148
mitochondrion organization GO:0007005 4 0.145
Yeast
establishment of localization GO:0051234 244 0.144
Worm
immune system development GO:0002520 191 0.133
stem cell proliferation GO:0072089 4 0.129
branched chain amino acid metabolic process GO:0009081 1 0.128
cellular macromolecule metabolic process GO:0044260 391 0.128
maintenance of location GO:0051235 4 0.127
small molecule catabolic process GO:0044282 3 0.125
regulation of multicellular organism growth GO:0040014 4 0.115
mitochondrion morphogenesis GO:0070584 2 0.111
gene expression GO:0010467 252 0.105
cellular component disassembly GO:0022411 1 0.102
mitochondrial electron transport nadh to ubiquinone GO:0006120 1 0.100
cellular biosynthetic process GO:0044249 286 0.099
cellular component movement GO:0006928 335 0.098
single organism localization GO:1902578 225 0.098
cellular amino acid metabolic process GO:0006520 7 0.094
ion transmembrane transport GO:0034220 91 0.092
oxidation reduction process GO:0055114 41 0.088
positive regulation of developmental process GO:0051094 50 0.087
spermatid development GO:0007286 2 0.086
muscle structure development GO:0061061 196 0.083
organic acid metabolic process GO:0006082 31 0.082
Yeast
positive regulation of cellular process GO:0048522 201 0.081
nitrogen compound metabolic process GO:0006807 319 0.080
biosynthetic process GO:0009058 294 0.079
heart development GO:0007507 313 0.078
digestive tract morphogenesis GO:0048546 231 0.073
growth GO:0040007 174 0.070
response to external stimulus GO:0009605 264 0.068
morphogenesis of an epithelium GO:0002009 333 0.068
spermatid differentiation GO:0048515 2 0.067
myotube differentiation GO:0014902 45 0.065
heterocycle metabolic process GO:0046483 290 0.065
phagocytosis GO:0006909 3 0.064
aromatic compound biosynthetic process GO:0019438 217 0.063
organelle organization GO:0006996 227 0.062
Yeast
respiratory electron transport chain GO:0022904 2 0.062
regulation of biological quality GO:0065008 263 0.061
localization of cell GO:0051674 244 0.060
oxoacid metabolic process GO:0043436 31 0.060
Yeast
monocarboxylic acid catabolic process GO:0072329 3 0.060
hydrogen peroxide metabolic process GO:0042743 2 0.059
negative regulation of kinase activity GO:0033673 4 0.057
organic cyclic compound metabolic process GO:1901360 301 0.056
positive regulation of biological process GO:0048518 253 0.056
organonitrogen compound metabolic process GO:1901564 74 0.056
response to stress GO:0006950 263 0.055
brain development GO:0007420 293 0.055
carboxylic acid metabolic process GO:0019752 22 0.054
Yeast
blood vessel morphogenesis GO:0048514 216 0.054
protein complex disassembly GO:0043241 1 0.054
cell proliferation GO:0008283 80 0.053
organic substance biosynthetic process GO:1901576 289 0.052
organic cyclic compound biosynthetic process GO:1901362 223 0.051
sulfur compound biosynthetic process GO:0044272 9 0.049
regeneration GO:0031099 91 0.049
carbohydrate derivative metabolic process GO:1901135 61 0.049
cellular nitrogen compound metabolic process GO:0034641 290 0.048
chordate embryonic development GO:0043009 271 0.048
regulation of developmental process GO:0050793 247 0.047
phosphate containing compound metabolic process GO:0006796 108 0.047
somatic muscle development GO:0007525 4 0.047
germ cell development GO:0007281 22 0.046
lipid storage GO:0019915 1 0.045
locomotion GO:0040011 313 0.045
Worm
macromolecular complex disassembly GO:0032984 1 0.044
lipid catabolic process GO:0016042 4 0.044
determination of left right symmetry GO:0007368 179 0.044
acetyl coa metabolic process GO:0006084 1 0.044
regulation of multicellular organismal process GO:0051239 277 0.044
striated muscle cell differentiation GO:0051146 129 0.043
neuroblast proliferation GO:0007405 2 0.043
gtp metabolic process GO:0046039 4 0.042
regulation of organ growth GO:0046620 3 0.042
dicarboxylic acid metabolic process GO:0043648 1 0.042
Yeast
regulation of nitrogen compound metabolic process GO:0051171 251 0.042
digestive system development GO:0055123 289 0.041
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.040
cellular nitrogen compound biosynthetic process GO:0044271 218 0.039
digestive tract development GO:0048565 265 0.039
regulation of endopeptidase activity GO:0052548 23 0.039
septum transversum development GO:0003343 4 0.038
alpha amino acid metabolic process GO:1901605 3 0.037
protein polymerization GO:0051258 4 0.036
regulation of cell communication GO:0010646 232 0.036
regulation of cellular amine metabolic process GO:0033238 0 0.036
membrane invagination GO:0010324 1 0.035
phagocytosis engulfment GO:0006911 1 0.035
regulation of neural precursor cell proliferation GO:2000177 3 0.035
muscle cell differentiation GO:0042692 139 0.035
blood vessel development GO:0001568 246 0.035
small molecule metabolic process GO:0044281 77 0.035
Yeast
positive regulation of multicellular organismal process GO:0051240 52 0.034
endocytosis GO:0006897 16 0.034
Worm
response to chemical GO:0042221 320 0.033
single organism organelle organization GO:1902589 199 0.033
embryonic heart tube development GO:0035050 133 0.032
regulation of dendrite development GO:0050773 3 0.032
cell migration GO:0016477 237 0.032
cellular amine metabolic process GO:0044106 2 0.032
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.032
embryonic organ development GO:0048568 381 0.031
multi organism process GO:0051704 134 0.031
cellular aromatic compound metabolic process GO:0006725 295 0.031
heart looping GO:0001947 94 0.031
purine containing compound metabolic process GO:0072521 29 0.031
protein modification process GO:0036211 100 0.031
amine metabolic process GO:0009308 2 0.031
signal transduction GO:0007165 455 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.030
adherens junction organization GO:0034332 4 0.030
monovalent inorganic cation transport GO:0015672 42 0.030
regulation of stem cell proliferation GO:0072091 2 0.029
somite development GO:0061053 96 0.029
macromolecular complex subunit organization GO:0043933 74 0.029
transmembrane transport GO:0055085 120 0.029
zymogen activation GO:0031638 3 0.029
regulation of nucleoside metabolic process GO:0009118 2 0.028
somitogenesis GO:0001756 87 0.028
cellular protein metabolic process GO:0044267 129 0.028
acyl coa biosynthetic process GO:0071616 1 0.027
regulation of membrane potential GO:0042391 23 0.027
inorganic cation transmembrane transport GO:0098662 50 0.027
single organism transport GO:0044765 206 0.027
tube morphogenesis GO:0035239 349 0.026
regulation of cellular ketone metabolic process GO:0010565 7 0.026
cofactor biosynthetic process GO:0051188 10 0.026
cellular component morphogenesis GO:0032989 336 0.026
regulation of signal transduction GO:0009966 225 0.026
positive regulation of metabolic process GO:0009893 108 0.026
epithelial tube morphogenesis GO:0060562 148 0.026
nucleic acid transport GO:0050657 2 0.025
regulation of cell shape GO:0008360 1 0.025
mitochondrial transport GO:0006839 2 0.025
response to organic substance GO:0010033 153 0.025
cellular amino acid biosynthetic process GO:0008652 2 0.025
muscle cell development GO:0055001 115 0.025
guanosine containing compound catabolic process GO:1901069 2 0.025
organonitrogen compound biosynthetic process GO:1901566 47 0.025
striated muscle cell development GO:0055002 108 0.024
meiotic nuclear division GO:0007126 4 0.024
gastrulation GO:0007369 208 0.024
regulation of fatty acid beta oxidation GO:0031998 1 0.024
cell surface receptor signaling pathway GO:0007166 325 0.024
cellular catabolic process GO:0044248 27 0.024
hematopoietic or lymphoid organ development GO:0048534 191 0.023
gtp catabolic process GO:0006184 2 0.023
positive regulation of gtp catabolic process GO:0033126 1 0.023
cellular component assembly GO:0022607 170 0.023
cognition GO:0050890 1 0.023
synaptic growth at neuromuscular junction GO:0051124 2 0.023
macromolecule biosynthetic process GO:0009059 227 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
hemopoiesis GO:0030097 183 0.023
transport GO:0006810 220 0.023
Worm
regulation of primary metabolic process GO:0080090 311 0.023
apoptotic process GO:0006915 116 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
epithelial cell morphogenesis GO:0003382 2 0.022
cellular lipid catabolic process GO:0044242 3 0.022
single organism biosynthetic process GO:0044711 71 0.022
wound healing GO:0042060 90 0.022
cellular localization GO:0051641 97 0.022
macromolecule modification GO:0043412 111 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
regulation of metabolic process GO:0019222 359 0.022
head development GO:0060322 303 0.022
vesicle mediated transport GO:0016192 22 0.022
Worm
energy derivation by oxidation of organic compounds GO:0015980 5 0.021
cation transport GO:0006812 81 0.021
embryonic hemopoiesis GO:0035162 53 0.021
embryonic heart tube morphogenesis GO:0003143 108 0.021
phosphorylation GO:0016310 69 0.021
ion transport GO:0006811 114 0.021
negative regulation of cellular process GO:0048523 283 0.021
negative regulation of dna recombination GO:0045910 2 0.020
regulation of stem cell differentiation GO:2000736 4 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
angiogenesis GO:0001525 158 0.020
regulation of fatty acid metabolic process GO:0019217 1 0.020
regulation of lipid catabolic process GO:0050994 2 0.020
reactive oxygen species metabolic process GO:0072593 6 0.019
gene silencing by rna GO:0031047 4 0.019
protein metabolic process GO:0019538 183 0.019
rna export from nucleus GO:0006405 1 0.019
positive regulation of glucose import GO:0046326 1 0.019
peptidyl serine modification GO:0018209 2 0.019
positive regulation of catabolic process GO:0009896 4 0.019
circadian sleep wake cycle sleep GO:0050802 1 0.019
actin filament based movement GO:0030048 1 0.019
regulation of epithelial cell proliferation GO:0050678 3 0.019
cell death GO:0008219 121 0.019
multicellular organismal metabolic process GO:0044236 2 0.018
establishment of localization in cell GO:0051649 77 0.018
nucleic acid metabolic process GO:0090304 244 0.018
vasculature development GO:0001944 278 0.018
regulation of peptidase activity GO:0052547 23 0.018
positive regulation of transport GO:0051050 2 0.018
response to wounding GO:0009611 116 0.018
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.018
regulation of mrna processing GO:0050684 3 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
regulation of gtpase activity GO:0043087 2 0.018
protein depolymerization GO:0051261 1 0.018
determination of bilateral symmetry GO:0009855 204 0.018
regulation of neurogenesis GO:0050767 87 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
segmentation GO:0035282 97 0.018
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.018
cell motility GO:0048870 244 0.017
fatty acid oxidation GO:0019395 1 0.017
reproduction GO:0000003 40 0.017
Worm
regulation of myotube differentiation GO:0010830 2 0.017
protein localization to plasma membrane GO:0072659 1 0.017
positive regulation of stem cell proliferation GO:2000648 1 0.017
cellular response to organic substance GO:0071310 105 0.017
cellular protein complex disassembly GO:0043624 1 0.017
circadian sleep wake cycle process GO:0022410 2 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
negative regulation of neural precursor cell proliferation GO:2000178 1 0.017
generation of neurons GO:0048699 385 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
negative regulation of cell communication GO:0010648 96 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
regulation of cardiac muscle tissue development GO:0055024 1 0.017
regulation of dna templated transcription in response to stress GO:0043620 0 0.016
syncytium formation GO:0006949 12 0.016
regulation of response to stimulus GO:0048583 269 0.016
cellular component biogenesis GO:0044085 178 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
purine nucleotide metabolic process GO:0006163 27 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
organic substance catabolic process GO:1901575 28 0.016
mitotic dna damage checkpoint GO:0044773 4 0.016
cellular carbohydrate metabolic process GO:0044262 4 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
anterior posterior pattern specification GO:0009952 152 0.016
specification of symmetry GO:0009799 204 0.016
cell morphogenesis GO:0000902 289 0.016
sexual reproduction GO:0019953 36 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
nucleoside phosphate metabolic process GO:0006753 28 0.016
p38mapk cascade GO:0038066 1 0.016
neurotransmitter transport GO:0006836 2 0.016
nucleobase containing small molecule metabolic process GO:0055086 32 0.015
ribose phosphate metabolic process GO:0019693 27 0.015
multicellular organismal reproductive process GO:0048609 35 0.015
cellular protein modification process GO:0006464 100 0.015
convergent extension involved in gastrulation GO:0060027 71 0.015
regulation of cellular component organization GO:0051128 86 0.015
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.015
digestive tract mesoderm development GO:0007502 1 0.015
fatty acid transport GO:0015908 1 0.015
nucleotide metabolic process GO:0009117 28 0.015
peptidyl threonine phosphorylation GO:0018107 1 0.015
cell substrate adhesion GO:0031589 4 0.015
regulation of cellular protein metabolic process GO:0032268 52 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.015
nuclear transport GO:0051169 4 0.015
inorganic ion transmembrane transport GO:0098660 57 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
ribonucleoside metabolic process GO:0009119 11 0.014
plasma membrane repair GO:0001778 2 0.014
phosphorus metabolic process GO:0006793 109 0.014
rna metabolic process GO:0016070 219 0.014
protein localization to nucleus GO:0034504 3 0.014
transcription dna templated GO:0006351 181 0.014
organophosphate biosynthetic process GO:0090407 23 0.014
regulation of signaling GO:0023051 235 0.014
protein import GO:0017038 3 0.014
liver development GO:0001889 96 0.014
glial cell migration GO:0008347 3 0.014
eye development GO:0001654 277 0.014
carbohydrate derivative biosynthetic process GO:1901137 43 0.014
regulation of synapse assembly GO:0051963 3 0.014
organelle assembly GO:0070925 110 0.014
dorsal ventral pattern formation GO:0009953 125 0.014
negative regulation of multicellular organismal process GO:0051241 69 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.014
regulation of cell development GO:0060284 100 0.014
determination of heart left right asymmetry GO:0061371 117 0.014
nucleoside triphosphate biosynthetic process GO:0009142 2 0.014
positive regulation of neural precursor cell proliferation GO:2000179 1 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
purine ribonucleoside metabolic process GO:0046128 10 0.013
thioester metabolic process GO:0035383 1 0.013
cellular ketone metabolic process GO:0042180 11 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
positive regulation of cysteine type endopeptidase activity GO:2001056 10 0.013
lipid oxidation GO:0034440 1 0.013
regulation of mrna catabolic process GO:0061013 3 0.013
negative regulation of biological process GO:0048519 304 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
skeletal system development GO:0001501 181 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
immune system process GO:0002376 241 0.013
generation of precursor metabolites and energy GO:0006091 5 0.013
positive regulation of ras gtpase activity GO:0032320 1 0.013
fin development GO:0033333 77 0.013
regulation of establishment of protein localization GO:0070201 4 0.013
oogenesis GO:0048477 14 0.013
regulation of mrna 3 end processing GO:0031440 1 0.013
nucleoside biosynthetic process GO:0009163 2 0.013
sleep GO:0030431 1 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
neuron differentiation GO:0030182 353 0.013
regulation of developmental growth GO:0048638 38 0.013
regulation of protein depolymerization GO:1901879 1 0.012
appendage development GO:0048736 80 0.012
mesenchymal cell proliferation GO:0010463 1 0.012
meiotic cell cycle process GO:1903046 3 0.012
response to drug GO:0042493 3 0.012
regulation of nervous system development GO:0051960 90 0.012
response to nutrient GO:0007584 3 0.012
proteolysis GO:0006508 38 0.012
fatty acid beta oxidation GO:0006635 1 0.012
regulation of cell substrate adhesion GO:0010810 1 0.012
regulation of striated muscle contraction GO:0006942 2 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
regulation of phosphorus metabolic process GO:0051174 43 0.012
proepicardium development GO:0003342 4 0.012
cellular component maintenance GO:0043954 3 0.012
regulation of neurological system process GO:0031644 2 0.012
retina development in camera type eye GO:0060041 146 0.012
establishment of rna localization GO:0051236 3 0.012
cytoskeleton organization GO:0007010 96 0.012
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.012
cation transmembrane transport GO:0098655 65 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
regulation of circadian rhythm GO:0042752 4 0.012
actin cytoskeleton organization GO:0030036 63 0.012
system process GO:0003008 185 0.012
catabolic process GO:0009056 32 0.012
positive regulation of hydrolase activity GO:0051345 13 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
regulation of gene expression GO:0010468 265 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
peptidyl threonine modification GO:0018210 1 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
adult behavior GO:0030534 2 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
multicellular organism reproduction GO:0032504 35 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
regulation of synapse organization GO:0050807 3 0.011
macromolecular complex assembly GO:0065003 35 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
negative regulation of cytokine production GO:0001818 1 0.011
positive regulation of protein kinase b signaling GO:0051897 1 0.011
purine ribonucleotide metabolic process GO:0009150 27 0.011
tissue regeneration GO:0042246 74 0.011
intracellular signal transduction GO:0035556 85 0.011
regulation of fatty acid oxidation GO:0046320 1 0.011
neurotransmitter secretion GO:0007269 2 0.011
regulation of molecular function GO:0065009 70 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
meiosis i GO:0007127 1 0.011
atp metabolic process GO:0046034 5 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
polyol metabolic process GO:0019751 1 0.011
protein acetylation GO:0006473 2 0.011
regulation of sodium ion transport GO:0002028 2 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.010
response to vitamin GO:0033273 3 0.010
heterocycle catabolic process GO:0046700 15 0.010
regulation of multicellular organismal development GO:2000026 223 0.010
hydrogen ion transmembrane transport GO:1902600 6 0.010
regulation of behavior GO:0050795 24 0.010
nitric oxide metabolic process GO:0046209 2 0.010
notochord development GO:0030903 54 0.010
organophosphate metabolic process GO:0019637 37 0.010
embryonic organ morphogenesis GO:0048562 274 0.010
cellular response to oxygen levels GO:0071453 1 0.010
negative regulation of synapse assembly GO:0051964 2 0.010
long chain fatty acid transport GO:0015909 1 0.010
cell cycle GO:0007049 93 0.010
central nervous system development GO:0007417 387 0.010
regulation of protein targeting GO:1903533 2 0.010
developmental process involved in reproduction GO:0003006 27 0.010

dlst disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.133
disease of metabolism DOID:0014667 0 0.085
nervous system disease DOID:863 0 0.068
mitochondrial metabolism disease DOID:700 0 0.065
inherited metabolic disorder DOID:655 0 0.065
cardiovascular system disease DOID:1287 0 0.027
amino acid metabolic disorder DOID:9252 0 0.026
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.026
neuromuscular disease DOID:440 0 0.021
charcot marie tooth disease DOID:10595 0 0.021
neuropathy DOID:870 0 0.021
musculoskeletal system disease DOID:17 0 0.016
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011