Danio rerio

32 known processes

dlx2a

distal-less homeobox gene 2a

(Aliases: dlx-2,zgc:110518,dlx2)

dlx2a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
embryonic organ development GO:0048568 381 0.998
head development GO:0060322 303 0.997
auditory receptor cell fate commitment GO:0009912 4 0.996
embryonic organ morphogenesis GO:0048562 274 0.995
cellular macromolecule metabolic process GO:0044260 391 0.994
embryonic skeletal system development GO:0048706 97 0.993
regionalization GO:0003002 274 0.993
inner ear receptor cell fate commitment GO:0060120 4 0.992
biosynthetic process GO:0009058 294 0.992
cellular nitrogen compound metabolic process GO:0034641 290 0.988
forebrain neuron fate commitment GO:0021877 1 0.981
trigeminal nerve development GO:0021559 3 0.978
auditory receptor cell fate specification GO:0042667 2 0.975
limb bud formation GO:0060174 2 0.975
regulation of chondrocyte differentiation GO:0032330 1 0.973
skeletal system development GO:0001501 181 0.973
positive regulation of cellular process GO:0048522 201 0.968
heterocycle metabolic process GO:0046483 290 0.968
morphogenesis of an epithelium GO:0002009 333 0.967
regulation of nitrogen compound metabolic process GO:0051171 251 0.965
forebrain generation of neurons GO:0021872 14 0.965
brain development GO:0007420 293 0.964
regulation of macromolecule metabolic process GO:0060255 317 0.960
embryonic limb morphogenesis GO:0030326 2 0.957
positive regulation of nucleic acid templated transcription GO:1903508 57 0.955
connective tissue development GO:0061448 99 0.952
sensory organ development GO:0007423 393 0.947
response to external stimulus GO:0009605 264 0.945
cellular biosynthetic process GO:0044249 286 0.945
inner ear development GO:0048839 126 0.940
ear morphogenesis GO:0042471 64 0.937
nucleobase containing compound biosynthetic process GO:0034654 205 0.937
positive regulation of rna metabolic process GO:0051254 59 0.936
inner ear morphogenesis GO:0042472 63 0.935
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.934
regulation of metabolic process GO:0019222 359 0.933
forebrain neuron development GO:0021884 7 0.933
neuron differentiation GO:0030182 353 0.932
regulation of macromolecule biosynthetic process GO:0010556 225 0.931
nitrogen compound metabolic process GO:0006807 319 0.930
organic cyclic compound metabolic process GO:1901360 301 0.925
sensory organ morphogenesis GO:0090596 200 0.918
auditory receptor cell differentiation GO:0042491 15 0.918
positive regulation of macromolecule metabolic process GO:0010604 93 0.913
otic vesicle morphogenesis GO:0071600 34 0.910
positive regulation of biological process GO:0048518 253 0.909
regulation of cellular metabolic process GO:0031323 320 0.908
generation of neurons GO:0048699 385 0.903
transcription dna templated GO:0006351 181 0.894
cellular aromatic compound metabolic process GO:0006725 295 0.889
neuron fate commitment GO:0048663 26 0.885
neural crest cell differentiation GO:0014033 72 0.884
regulation of transcription involved in cell fate commitment GO:0060850 1 0.877
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.875
negative regulation of gene expression GO:0010629 65 0.874
positive regulation of metabolic process GO:0009893 108 0.870
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.869
locomotion GO:0040011 313 0.867
embryonic camera type eye development GO:0031076 29 0.861
heterocycle biosynthetic process GO:0018130 215 0.859
neural crest cell development GO:0014032 62 0.854
otic vesicle development GO:0071599 42 0.852
diencephalon development GO:0021536 58 0.844
forebrain development GO:0030900 96 0.839
fin development GO:0033333 77 0.836
positive regulation of biosynthetic process GO:0009891 68 0.834
regulation of cellular biosynthetic process GO:0031326 245 0.831
regulation of biosynthetic process GO:0009889 250 0.822
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.817
localization of cell GO:0051674 244 0.812
nucleic acid templated transcription GO:0097659 181 0.810
negative regulation of nucleic acid templated transcription GO:1903507 45 0.806
neuron projection guidance GO:0097485 86 0.805
forebrain neuron differentiation GO:0021879 14 0.802
regulation of rna metabolic process GO:0051252 224 0.782
nucleobase containing compound metabolic process GO:0006139 274 0.780
stem cell development GO:0048864 82 0.770
dorsal ventral pattern formation GO:0009953 125 0.767
negative regulation of biosynthetic process GO:0009890 55 0.765
regulation of nucleic acid templated transcription GO:1903506 213 0.764
positive regulation of cellular biosynthetic process GO:0031328 68 0.741
ear development GO:0043583 127 0.741
axon development GO:0061564 166 0.740
positive regulation of transcription dna templated GO:0045893 57 0.736
telencephalon development GO:0021537 14 0.734
neuron fate specification GO:0048665 20 0.724
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.723
positive regulation of gene expression GO:0010628 71 0.716
negative regulation of cellular metabolic process GO:0031324 77 0.715
regulation of primary metabolic process GO:0080090 311 0.715
regulation of transcription dna templated GO:0006355 213 0.705
organic cyclic compound biosynthetic process GO:1901362 223 0.702
neuron projection morphogenesis GO:0048812 161 0.700
organic substance biosynthetic process GO:1901576 289 0.693
response to chemical GO:0042221 320 0.686
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.684
negative regulation of biological process GO:0048519 304 0.684
cell motility GO:0048870 244 0.670
mesenchymal cell differentiation GO:0048762 87 0.663
regulation of rna biosynthetic process GO:2001141 213 0.662
cartilage morphogenesis GO:0060536 13 0.659
cellular nitrogen compound biosynthetic process GO:0044271 218 0.648
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.645
negative regulation of transcription dna templated GO:0045892 45 0.643
embryonic skeletal system morphogenesis GO:0048704 93 0.634
eye development GO:0001654 277 0.627
odontogenesis of dentin containing tooth GO:0042475 1 0.621
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.619
epithalamus development GO:0021538 10 0.607
nucleic acid metabolic process GO:0090304 244 0.606
cell proliferation in hindbrain GO:0021534 4 0.595
cell migration involved in gastrulation GO:0042074 79 0.593
mechanoreceptor differentiation GO:0042490 37 0.589
heart valve formation GO:0003188 4 0.589
limb development GO:0060173 8 0.583
regulation of multicellular organismal process GO:0051239 277 0.581
embryonic camera type eye formation GO:0060900 10 0.573
response to organic substance GO:0010033 153 0.570
negative regulation of rna metabolic process GO:0051253 48 0.565
cell migration GO:0016477 237 0.561
epidermal cell fate specification GO:0009957 4 0.554
transcription from rna polymerase ii promoter GO:0006366 80 0.548
chordate embryonic development GO:0043009 271 0.545
regulation of gene expression GO:0010468 265 0.544
macromolecule biosynthetic process GO:0009059 227 0.542
axonogenesis GO:0007409 152 0.539
midbrain hindbrain boundary development GO:0030917 23 0.539
embryonic viscerocranium morphogenesis GO:0048703 52 0.538
bmp signaling pathway involved in heart jogging GO:0003303 14 0.531
skeletal system morphogenesis GO:0048705 102 0.531
central nervous system development GO:0007417 387 0.528
embryonic camera type eye morphogenesis GO:0048596 19 0.507
gene expression GO:0010467 252 0.499
pancreatic d cell development GO:0003324 1 0.499
mesoderm development GO:0007498 88 0.494
cell proliferation involved in heart morphogenesis GO:0061323 2 0.490
larval development GO:0002164 2 0.487
semicircular canal formation GO:0060876 4 0.482
ectodermal placode morphogenesis GO:0071697 32 0.481
cell part morphogenesis GO:0032990 246 0.477
neural tube development GO:0021915 62 0.467
epithelial cell fate commitment GO:0072148 11 0.463
fourth ventricle development GO:0021592 8 0.460
somitogenesis GO:0001756 87 0.458
inner ear receptor cell differentiation GO:0060113 29 0.445
cell fate specification GO:0001708 68 0.441
negative regulation of macromolecule metabolic process GO:0010605 76 0.435
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.429
hair cell differentiation GO:0035315 32 0.426
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.426
otic placode formation GO:0043049 23 0.425
response to abiotic stimulus GO:0009628 122 0.423
heart development GO:0007507 313 0.420
rna metabolic process GO:0016070 219 0.417
stem cell proliferation GO:0072089 4 0.414
cellular macromolecule biosynthetic process GO:0034645 224 0.413
closure of optic fissure GO:0061386 6 0.408
cell fate commitment GO:0045165 99 0.406
cartilage development GO:0051216 96 0.392
aromatic compound biosynthetic process GO:0019438 217 0.390
type b pancreatic cell development GO:0003323 4 0.389
pituitary gland development GO:0021983 16 0.380
cellular component movement GO:0006928 335 0.373
sprouting angiogenesis GO:0002040 53 0.371
positive regulation of cellular metabolic process GO:0031325 94 0.371
negative regulation of rna biosynthetic process GO:1902679 45 0.370
craniofacial suture morphogenesis GO:0097094 2 0.369
vasculogenesis GO:0001570 41 0.369
gabaergic neuron differentiation GO:0097154 2 0.367
otic vesicle formation GO:0030916 27 0.367
camera type eye photoreceptor cell differentiation GO:0060219 19 0.364
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.359
forebrain cell migration GO:0021885 1 0.357
mesodermal cell fate commitment GO:0001710 14 0.356
limb morphogenesis GO:0035108 7 0.356
pectoral fin development GO:0033339 50 0.353
regulation of apoptotic process GO:0042981 98 0.350
embryonic appendage morphogenesis GO:0035113 30 0.348
bmp signaling pathway GO:0030509 52 0.345
blood vessel development GO:0001568 246 0.342
regulation of glial cell differentiation GO:0045685 4 0.342
specification of organ identity GO:0010092 2 0.334
mesenchyme development GO:0060485 127 0.331
negative regulation of nervous system development GO:0051961 22 0.329
positive regulation of stem cell proliferation GO:2000648 1 0.324
sympathetic nervous system development GO:0048485 3 0.319
ameboidal type cell migration GO:0001667 143 0.317
mesenchymal cell proliferation GO:0010463 1 0.316
bmp signaling pathway involved in heart development GO:0061312 15 0.316
axon guidance GO:0007411 86 0.313
dopaminergic neuron differentiation GO:0071542 14 0.312
negative regulation of cellular biosynthetic process GO:0031327 55 0.310
cardiogenic plate morphogenesis GO:0003142 1 0.298
embryonic digestive tract morphogenesis GO:0048557 3 0.298
cerebellum morphogenesis GO:0021587 10 0.296
retinal ganglion cell axon guidance GO:0031290 35 0.294
urogenital system development GO:0001655 97 0.291
cell proliferation in midbrain GO:0033278 4 0.290
response to stress GO:0006950 263 0.281
retina development in camera type eye GO:0060041 146 0.280
camera type eye development GO:0043010 222 0.279
regulation of axon extension involved in axon guidance GO:0048841 6 0.276
atrioventricular valve formation GO:0003190 3 0.275
ectodermal placode development GO:0071696 37 0.274
limbic system development GO:0021761 16 0.271
anterior posterior pattern specification GO:0009952 152 0.262
endocardial cushion formation GO:0003272 2 0.258
digestive system development GO:0055123 289 0.256
determination of dorsal ventral asymmetry GO:0048262 34 0.254
endocrine system development GO:0035270 65 0.250
nerve development GO:0021675 45 0.244
central nervous system neuron development GO:0021954 29 0.242
hindbrain development GO:0030902 91 0.235
morphogenesis of a branching epithelium GO:0061138 16 0.234
camera type eye morphogenesis GO:0048593 108 0.234
central nervous system neuron differentiation GO:0021953 74 0.230
epithelial cell differentiation GO:0030855 116 0.229
rna biosynthetic process GO:0032774 181 0.224
chemotaxis GO:0006935 104 0.224
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.221
negative regulation of axon guidance GO:1902668 1 0.219
endodermal cell fate determination GO:0007493 2 0.216
embryonic cranial skeleton morphogenesis GO:0048701 90 0.212
organonitrogen compound metabolic process GO:1901564 74 0.210
regulation of developmental process GO:0050793 247 0.208
notochord development GO:0030903 54 0.207
metencephalon development GO:0022037 27 0.202
locomotory behavior GO:0007626 34 0.200
proepicardium development GO:0003342 4 0.199
embryonic heart tube development GO:0035050 133 0.198
axon extension GO:0048675 45 0.197
neuron development GO:0048666 262 0.196
regulation of axon guidance GO:1902667 8 0.195
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.192
regulation of oligodendrocyte differentiation GO:0048713 1 0.191
neuroblast fate commitment GO:0014017 1 0.191
cell proliferation GO:0008283 80 0.188
negative regulation of cell differentiation GO:0045596 46 0.187
appendage morphogenesis GO:0035107 56 0.179
cellular response to chemical stimulus GO:0070887 157 0.178
cellular component morphogenesis GO:0032989 336 0.178
mesenchymal cell development GO:0014031 78 0.177
positive regulation of rna biosynthetic process GO:1902680 57 0.173
cell morphogenesis GO:0000902 289 0.172
cell morphogenesis involved in differentiation GO:0000904 195 0.172
regulation of signaling GO:0023051 235 0.172
cranial nerve development GO:0021545 42 0.171
glandular epithelial cell differentiation GO:0002067 9 0.169
digestive tract development GO:0048565 265 0.168
endocardial cushion morphogenesis GO:0003203 3 0.166
olfactory lobe development GO:0021988 4 0.166
response to growth factor GO:0070848 39 0.166
apoptotic process GO:0006915 116 0.162
odontogenesis GO:0042476 9 0.162
reproduction GO:0000003 40 0.162
regulation of reproductive process GO:2000241 4 0.161
olfactory bulb development GO:0021772 4 0.161
negative regulation of cellular process GO:0048523 283 0.160
glial cell migration GO:0008347 3 0.159
blood vessel morphogenesis GO:0048514 216 0.157
neural crest cell migration GO:0001755 42 0.153
response to corticosteroid GO:0031960 1 0.151
cell proliferation in forebrain GO:0021846 3 0.150
central nervous system projection neuron axonogenesis GO:0021952 15 0.150
neural tube patterning GO:0021532 33 0.148
smoothened signaling pathway GO:0007224 30 0.147
cell projection organization GO:0030030 284 0.146
morphogenesis of an epithelial fold GO:0060571 1 0.145
chondrocyte development GO:0002063 4 0.144
photoreceptor cell differentiation GO:0046530 55 0.143
ectodermal placode formation GO:0060788 26 0.143
regulation of endodermal cell fate specification GO:0042663 15 0.143
auditory receptor cell fate determination GO:0042668 2 0.142
epithelial to mesenchymal transition GO:0001837 21 0.141
regulation of programmed cell death GO:0043067 101 0.140
neuron projection extension GO:1990138 45 0.140
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.140
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.138
reproductive process GO:0022414 40 0.138
cranial suture morphogenesis GO:0060363 1 0.138
glial cell fate specification GO:0021780 4 0.137
thalamus development GO:0021794 6 0.136
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.135
olfactory placode development GO:0071698 12 0.134
endodermal cell differentiation GO:0035987 19 0.133
catecholamine biosynthetic process GO:0042423 2 0.133
negative regulation of metabolic process GO:0009892 86 0.133
medial fin development GO:0033338 16 0.130
photoreceptor cell fate commitment GO:0046552 1 0.127
pericardium morphogenesis GO:0003344 1 0.127
organ formation GO:0048645 17 0.127
regulation of multicellular organismal development GO:2000026 223 0.126
olfactory placode morphogenesis GO:0071699 7 0.126
cellular response to organic substance GO:0071310 105 0.124
phenol containing compound biosynthetic process GO:0046189 4 0.124
appendage development GO:0048736 80 0.122
dorsal ventral neural tube patterning GO:0021904 1 0.121
morphogenesis of embryonic epithelium GO:0016331 30 0.120
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.118
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.117
response to immobilization stress GO:0035902 1 0.116
endocardial progenitor cell migration to the midline involved in heart field formation GO:0003262 4 0.116
epidermal cell differentiation GO:0009913 36 0.115
small molecule metabolic process GO:0044281 77 0.115
medial fin morphogenesis GO:0035141 14 0.114
cellular response to organic cyclic compound GO:0071407 38 0.113
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.111
developmental growth involved in morphogenesis GO:0060560 86 0.110
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.109
stem cell differentiation GO:0048863 117 0.108
regulation of cell development GO:0060284 100 0.105
optomotor response GO:0071632 1 0.104
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.103
negative regulation of multicellular organismal process GO:0051241 69 0.102
developmental growth GO:0048589 166 0.102
regulation of binding GO:0051098 3 0.102
pancreatic a cell development GO:0003322 2 0.101
fin morphogenesis GO:0033334 53 0.100
axon midline choice point recognition GO:0016199 4 0.099
androgen metabolic process GO:0008209 2 0.099
anterior posterior axon guidance GO:0033564 5 0.098
regulation of bone mineralization GO:0030500 2 0.098
specification of symmetry GO:0009799 204 0.097
regulation of cell differentiation GO:0045595 142 0.097
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.097
retinal rod cell development GO:0046548 4 0.097
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.095
wound healing GO:0042060 90 0.094
endochondral bone morphogenesis GO:0060350 8 0.094
cell projection morphogenesis GO:0048858 244 0.094
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.094
semicircular canal development GO:0060872 24 0.093
hindbrain morphogenesis GO:0021575 22 0.092
atrial ventricular junction remodeling GO:0003294 2 0.092
spinal cord motor neuron differentiation GO:0021522 26 0.092
cellular amino acid metabolic process GO:0006520 7 0.091
brain segmentation GO:0035284 6 0.089
direct ossification GO:0036072 3 0.087
peripheral nervous system neuron axonogenesis GO:0048936 13 0.087
response to mechanical stimulus GO:0009612 24 0.086
epithelial tube morphogenesis GO:0060562 148 0.086
cellular ketone metabolic process GO:0042180 11 0.085
negative regulation of programmed cell death GO:0043069 58 0.085
positive regulation of skeletal muscle tissue development GO:0048643 1 0.085
stem cell maintenance GO:0019827 4 0.085
central nervous system neuron axonogenesis GO:0021955 18 0.085
cartilage condensation GO:0001502 3 0.085
motor neuron axon guidance GO:0008045 23 0.082
dopamine biosynthetic process GO:0042416 2 0.081
endodermal cell fate specification GO:0001714 17 0.081
determination of intestine left right asymmetry GO:0071908 2 0.080
hypothalamus development GO:0021854 14 0.080
regulation of axon extension GO:0030516 24 0.080
regulation of cell proliferation involved in tissue homeostasis GO:0060784 2 0.080
cellular response to lipid GO:0071396 39 0.079
catecholamine metabolic process GO:0006584 2 0.078
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.077
organic acid metabolic process GO:0006082 31 0.077
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.077
neuron migration GO:0001764 22 0.074
death GO:0016265 121 0.074
regulation of anatomical structure morphogenesis GO:0022603 130 0.073
somite development GO:0061053 96 0.072
behavior GO:0007610 74 0.071
regulation of cell proliferation GO:0042127 37 0.070
regulation of response to stimulus GO:0048583 269 0.070
regulation of epithelial cell proliferation GO:0050678 3 0.069
thrombocyte differentiation GO:0002574 4 0.069
cellular response to growth factor stimulus GO:0071363 39 0.068
ossification GO:0001503 23 0.067
negative regulation of apoptotic process GO:0043066 55 0.067
heart formation GO:0060914 13 0.066
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.065
embryonic heart tube formation GO:0003144 1 0.065
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.065
paraxial mesoderm morphogenesis GO:0048340 2 0.065
regulation of epithelial to mesenchymal transition GO:0010717 3 0.064
regulation of mesenchymal cell proliferation GO:0010464 1 0.064
axon extension involved in axon guidance GO:0048846 10 0.063
bone mineralization GO:0030282 9 0.063
neural crest formation GO:0014029 14 0.062
enzyme linked receptor protein signaling pathway GO:0007167 106 0.060
osteoblast differentiation GO:0001649 5 0.059
eye morphogenesis GO:0048592 144 0.059
oxoacid metabolic process GO:0043436 31 0.058
fin regeneration GO:0031101 51 0.058
pharyngeal system development GO:0060037 18 0.058
single organism metabolic process GO:0044710 217 0.057
rostrocaudal neural tube patterning GO:0021903 29 0.057
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.056
negative regulation of signaling GO:0023057 96 0.056
angiogenesis GO:0001525 158 0.056
catechol containing compound biosynthetic process GO:0009713 2 0.056
endocardial cushion development GO:0003197 6 0.055
sexual reproduction GO:0019953 36 0.055
regulation of locomotion GO:0040012 55 0.054
axis elongation GO:0003401 31 0.054
response to glucocorticoid GO:0051384 1 0.054
heart morphogenesis GO:0003007 156 0.054
cellular response to retinoic acid GO:0071300 1 0.053
regulation of cell fate commitment GO:0010453 22 0.052
heart valve morphogenesis GO:0003179 8 0.052
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.051
positive regulation of cell cycle GO:0045787 3 0.050
neuron projection development GO:0031175 180 0.050
habenula development GO:0021986 9 0.050
hematopoietic or lymphoid organ development GO:0048534 191 0.049
spinal cord radial glial cell differentiation GO:0021531 2 0.049
regulation of dendrite development GO:0050773 3 0.048
regulation of molecular function GO:0065009 70 0.048
endocardium formation GO:0060214 1 0.046
cellular response to external stimulus GO:0071496 2 0.046
regulation of cartilage development GO:0061035 7 0.046
stem cell division GO:0017145 1 0.046
hypothalamus cell differentiation GO:0021979 4 0.046
regulation of cellular ketone metabolic process GO:0010565 7 0.045
regulation of biomineral tissue development GO:0070167 2 0.045
internal peptidyl lysine acetylation GO:0018393 2 0.045
aging GO:0007568 2 0.045
semicircular canal morphogenesis GO:0048752 18 0.045
photoreceptor cell development GO:0042461 40 0.045
anterior commissure morphogenesis GO:0021960 3 0.045
regulation of skeletal muscle fiber development GO:0048742 2 0.044
positive regulation of muscle tissue development GO:1901863 1 0.044
immune system process GO:0002376 241 0.044
patterning of blood vessels GO:0001569 15 0.044
heart field specification GO:0003128 1 0.043
pancreatic d cell differentiation GO:0003311 2 0.043
retinal cone cell differentiation GO:0042670 12 0.043
astrocyte differentiation GO:0048708 1 0.042
regulation of cell fate specification GO:0042659 20 0.042
negative regulation of transcription elongation from rna polymerase ii promoter GO:0034244 1 0.042
spinal cord oligodendrocyte cell differentiation GO:0021529 5 0.042
retinal pigment epithelium development GO:0003406 8 0.042
embryonic neurocranium morphogenesis GO:0048702 15 0.041
regulation of bmp signaling pathway GO:0030510 39 0.041
proximal distal pattern formation GO:0009954 1 0.040
carboxylic acid metabolic process GO:0019752 22 0.040
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.039
tissue remodeling GO:0048771 4 0.039
negative regulation of cell death GO:0060548 60 0.039
muscle cell differentiation GO:0042692 139 0.038
negative regulation of muscle cell differentiation GO:0051148 1 0.037
ventricular cardiac muscle cell differentiation GO:0055012 6 0.037
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 0.037
cell surface receptor signaling pathway GO:0007166 325 0.037
regulation of cell communication GO:0010646 232 0.036
taxis GO:0042330 109 0.036
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.036
vasculature development GO:0001944 278 0.036
positive regulation of gastrulation GO:2000543 2 0.036
single organism behavior GO:0044708 24 0.036
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.036
phosphorus metabolic process GO:0006793 109 0.036
eye photoreceptor cell differentiation GO:0001754 45 0.036
endoderm formation GO:0001706 29 0.035
regulation of cellular response to growth factor stimulus GO:0090287 35 0.035
chemosensory behavior GO:0007635 1 0.035
enteroendocrine cell differentiation GO:0035883 9 0.035
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.034
oligodendrocyte cell fate specification GO:0021778 4 0.034
tube formation GO:0035148 25 0.034
developmental cell growth GO:0048588 52 0.034
negative regulation of neurogenesis GO:0050768 20 0.034
embryonic skeletal joint morphogenesis GO:0060272 3 0.034
cellular amine metabolic process GO:0044106 2 0.033
lateral inhibition GO:0046331 1 0.033
cerebellar cortex formation GO:0021697 5 0.032
embryonic pectoral fin morphogenesis GO:0035118 24 0.032
mesenchyme morphogenesis GO:0072132 5 0.032
cellular localization GO:0051641 97 0.032
embryonic pattern specification GO:0009880 44 0.031
smooth muscle tissue development GO:0048745 1 0.031
gland development GO:0048732 143 0.031
mesodermal cell differentiation GO:0048333 21 0.031
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.031
regulation of cell death GO:0010941 103 0.031
response to lipid GO:0033993 60 0.030
morphogenesis of a branching structure GO:0001763 21 0.030
innervation GO:0060384 3 0.030
cerebellum development GO:0021549 17 0.030
neural crest cell fate specification GO:0014036 5 0.029
cardioblast differentiation GO:0010002 9 0.029
branching morphogenesis of a nerve GO:0048755 4 0.029
cell differentiation in spinal cord GO:0021515 40 0.029
muscle structure development GO:0061061 196 0.028
embryonic eye morphogenesis GO:0048048 30 0.028
regulation of nervous system development GO:0051960 90 0.028
small gtpase mediated signal transduction GO:0007264 8 0.028
transport GO:0006810 220 0.028

dlx2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.152
bone development disease DOID:0080006 0 0.126
bone disease DOID:0080001 0 0.126
disease of anatomical entity DOID:7 0 0.126
dysostosis DOID:1934 0 0.126
musculoskeletal system disease DOID:17 0 0.126
connective tissue disease DOID:65 0 0.126
osteochondrodysplasia DOID:2256 0 0.110
disease of metabolism DOID:0014667 0 0.033