Danio rerio

0 known processes

dlx4a

distal-less homeobox gene 4a

(Aliases: dlx8)

dlx4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
odontogenesis of dentin containing tooth GO:0042475 1 0.976
auditory receptor cell fate specification GO:0042667 2 0.954
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.935
Zebrafish
ear development GO:0043583 127 0.924
Zebrafish
inner ear receptor cell fate commitment GO:0060120 4 0.918
Zebrafish
embryonic organ development GO:0048568 381 0.901
Zebrafish
epidermal cell differentiation GO:0009913 36 0.900
Zebrafish
eye development GO:0001654 277 0.859
Zebrafish
otic vesicle formation GO:0030916 27 0.832
Zebrafish
sensory organ morphogenesis GO:0090596 200 0.829
Zebrafish
sensory organ development GO:0007423 393 0.826
Zebrafish
otic vesicle morphogenesis GO:0071600 34 0.820
Zebrafish
fin development GO:0033333 77 0.797
Zebrafish
mechanoreceptor differentiation GO:0042490 37 0.784
Zebrafish
pectoral fin development GO:0033339 50 0.766
Zebrafish
regulation of biosynthetic process GO:0009889 250 0.759
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.749
Fly
chordate embryonic development GO:0043009 271 0.749
nucleic acid templated transcription GO:0097659 181 0.739
Fly
inner ear morphogenesis GO:0042472 63 0.725
Zebrafish
ectodermal placode formation GO:0060788 26 0.724
Zebrafish
skeletal system development GO:0001501 181 0.720
Zebrafish
ear morphogenesis GO:0042471 64 0.713
Zebrafish
trigeminal nerve development GO:0021559 3 0.699
Zebrafish
ectodermal placode development GO:0071696 37 0.695
Zebrafish
appendage development GO:0048736 80 0.694
Zebrafish Fly
nerve development GO:0021675 45 0.674
Zebrafish Fly
specification of symmetry GO:0009799 204 0.656
Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.642
Fly
larval development GO:0002164 2 0.633
Worm
ectodermal placode morphogenesis GO:0071697 32 0.632
Zebrafish
cell fate commitment GO:0045165 99 0.621
Zebrafish
regulation of transcription involved in cell fate commitment GO:0060850 1 0.612
transcription dna templated GO:0006351 181 0.608
Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.607
Fly
auditory receptor cell fate commitment GO:0009912 4 0.575
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.566
Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.558
response to mechanical stimulus GO:0009612 24 0.554
organic substance biosynthetic process GO:1901576 289 0.550
Fly
cranial nerve development GO:0021545 42 0.532
Zebrafish Fly
nitrogen compound metabolic process GO:0006807 319 0.512
Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.506
Fly
heterocycle metabolic process GO:0046483 290 0.504
Fly
otic placode formation GO:0043049 23 0.493
Zebrafish
skeletal system morphogenesis GO:0048705 102 0.491
cartilage development GO:0051216 96 0.488
Zebrafish
cellular biosynthetic process GO:0044249 286 0.477
Fly
fin morphogenesis GO:0033334 53 0.475
Zebrafish
embryonic camera type eye development GO:0031076 29 0.460
cellular aromatic compound metabolic process GO:0006725 295 0.459
Fly
appendage morphogenesis GO:0035107 56 0.453
Zebrafish Fly
determination of bilateral symmetry GO:0009855 204 0.450
Fly
regulation of multicellular organismal process GO:0051239 277 0.447
response to abiotic stimulus GO:0009628 122 0.439
hair cell differentiation GO:0035315 32 0.424
Zebrafish
positive regulation of epithelial cell proliferation GO:0050679 1 0.397
rna metabolic process GO:0016070 219 0.396
Fly
auditory receptor cell differentiation GO:0042491 15 0.394
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.392
Fly
endocrine system development GO:0035270 65 0.383
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.380
Fly
signal transduction GO:0007165 455 0.366
regulation of multicellular organismal development GO:2000026 223 0.359
regulation of cellular biosynthetic process GO:0031326 245 0.356
Fly
response to external stimulus GO:0009605 264 0.355
medial fin morphogenesis GO:0035141 14 0.348
Zebrafish
epidermis development GO:0008544 48 0.333
Zebrafish
positive regulation of cellular process GO:0048522 201 0.331
Fly
death GO:0016265 121 0.331
regulation of developmental process GO:0050793 247 0.330
connective tissue development GO:0061448 99 0.305
Zebrafish
embryonic camera type eye formation GO:0060900 10 0.283
heart process GO:0003015 71 0.272
extrinsic apoptotic signaling pathway GO:0097191 3 0.266
inner ear development GO:0048839 126 0.263
Zebrafish
neuron development GO:0048666 262 0.262
Zebrafish
cell morphogenesis GO:0000902 289 0.261
transcription from rna polymerase ii promoter GO:0006366 80 0.255
embryonic camera type eye morphogenesis GO:0048596 19 0.252
neural nucleus development GO:0048857 15 0.249
cellular nitrogen compound metabolic process GO:0034641 290 0.248
Fly
compound eye development GO:0048749 2 0.248
central nervous system development GO:0007417 387 0.244
Fly
morphogenesis of an epithelium GO:0002009 333 0.244
Zebrafish
cellular response to chemical stimulus GO:0070887 157 0.242
embryonic skeletal system development GO:0048706 97 0.238
cranial suture morphogenesis GO:0060363 1 0.238
positive regulation of rna metabolic process GO:0051254 59 0.236
Fly
cellular component morphogenesis GO:0032989 336 0.236
inner ear receptor cell differentiation GO:0060113 29 0.232
Zebrafish
digestive system development GO:0055123 289 0.223
response to chemical GO:0042221 320 0.222
Fly
regulation of oligodendrocyte differentiation GO:0048713 1 0.221
membrane repolarization GO:0086009 2 0.219
glial cell differentiation GO:0010001 42 0.218
negative regulation of biological process GO:0048519 304 0.217
Fly
aromatic compound biosynthetic process GO:0019438 217 0.213
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.208
Fly
eye morphogenesis GO:0048592 144 0.206
ossification GO:0001503 23 0.205
olfactory placode morphogenesis GO:0071699 7 0.203
determination of heart left right asymmetry GO:0061371 117 0.201
macromolecule biosynthetic process GO:0009059 227 0.201
Fly
regulation of cell death GO:0010941 103 0.200
gliogenesis GO:0042063 45 0.196
nucleic acid metabolic process GO:0090304 244 0.192
Fly
negative regulation of multicellular organismal process GO:0051241 69 0.191
organic cyclic compound metabolic process GO:1901360 301 0.189
Fly
neural tube development GO:0021915 62 0.189
cell surface receptor signaling pathway GO:0007166 325 0.187
determination of left right symmetry GO:0007368 179 0.186
heart morphogenesis GO:0003007 156 0.185
camera type eye morphogenesis GO:0048593 108 0.182
response to nutrient GO:0007584 3 0.181
regulation of glial cell differentiation GO:0045685 4 0.179
regulation of metabolic process GO:0019222 359 0.177
Fly
epithelial cell fate commitment GO:0072148 11 0.177
Zebrafish
positive regulation of gene expression GO:0010628 71 0.175
Fly
response to endogenous stimulus GO:0009719 83 0.175
response to lipid GO:0033993 60 0.174
negative regulation of transcription dna templated GO:0045892 45 0.174
hindbrain morphogenesis GO:0021575 22 0.174
regulation of heart contraction GO:0008016 32 0.165
otic vesicle development GO:0071599 42 0.165
Zebrafish
retina development in camera type eye GO:0060041 146 0.165
biosynthetic process GO:0009058 294 0.164
Fly
determination of dorsal ventral asymmetry GO:0048262 34 0.157
Fly
cellular response to lipid GO:0071396 39 0.155
camera type eye development GO:0043010 222 0.155
Zebrafish
heart development GO:0007507 313 0.152
programmed cell death GO:0012501 119 0.149
locomotion GO:0040011 313 0.148
Worm
regulation of biological quality GO:0065008 263 0.148
negative regulation of metabolic process GO:0009892 86 0.146
Fly
cell fate specification GO:0001708 68 0.146
Zebrafish
response to vitamin GO:0033273 3 0.145
hindbrain development GO:0030902 91 0.140
heterocycle biosynthetic process GO:0018130 215 0.139
Fly
bone morphogenesis GO:0060349 11 0.139
odontogenesis GO:0042476 9 0.138
regulation of transcription dna templated GO:0006355 213 0.133
Fly
neuron differentiation GO:0030182 353 0.131
Zebrafish
regulation of rna biosynthetic process GO:2001141 213 0.129
Fly
muscle cell differentiation GO:0042692 139 0.128
cell death GO:0008219 121 0.126
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.126
blood circulation GO:0008015 87 0.126
glial cell migration GO:0008347 3 0.125
medial fin development GO:0033338 16 0.124
Zebrafish
regionalization GO:0003002 274 0.120
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.119
Worm
negative regulation of catabolic process GO:0009895 3 0.118
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.117
Fly
negative regulation of cellular metabolic process GO:0031324 77 0.116
regulation of cellular metabolic process GO:0031323 320 0.116
Fly
cellular response to organic substance GO:0071310 105 0.116
cell growth GO:0016049 57 0.115
positive regulation of biological process GO:0048518 253 0.115
Fly
determination of ventral identity GO:0048264 21 0.114
Fly
stem cell proliferation GO:0072089 4 0.113
cell migration GO:0016477 237 0.112
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.109
embryonic digestive tract morphogenesis GO:0048557 3 0.108
epithelial cell differentiation GO:0030855 116 0.108
Zebrafish
regulation of primary metabolic process GO:0080090 311 0.107
Fly
oligodendrocyte differentiation GO:0048709 23 0.107
olfactory lobe development GO:0021988 4 0.107
tube morphogenesis GO:0035239 349 0.106
mesenchymal cell proliferation GO:0010463 1 0.106
embryonic cranial skeleton morphogenesis GO:0048701 90 0.106
regulation of mesenchymal cell proliferation GO:0010464 1 0.104
cellular response to endogenous stimulus GO:0071495 68 0.104
embryonic limb morphogenesis GO:0030326 2 0.103
positive regulation of apoptotic process GO:0043065 29 0.103
inner ear receptor cell development GO:0060119 20 0.101
brain development GO:0007420 293 0.101
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.100
Fly
circulatory system process GO:0003013 87 0.100
cellular component movement GO:0006928 335 0.099
tissue regeneration GO:0042246 74 0.099
regulation of signaling GO:0023051 235 0.099
cellular response to steroid hormone stimulus GO:0071383 31 0.099
neuron projection morphogenesis GO:0048812 161 0.098
growth GO:0040007 174 0.095
nuclear transport GO:0051169 4 0.094
axonogenesis GO:0007409 152 0.094
system process GO:0003008 185 0.094
embryonic heart tube development GO:0035050 133 0.094
negative regulation of developmental process GO:0051093 65 0.093
response to radiation GO:0009314 51 0.091
lipid catabolic process GO:0016042 4 0.091
pancreas development GO:0031016 84 0.090
positive regulation of cellular biosynthetic process GO:0031328 68 0.090
Fly
striated muscle tissue development GO:0014706 110 0.088
epithelial tube morphogenesis GO:0060562 148 0.087
regulation of gene expression GO:0010468 265 0.086
Fly
cellular macromolecule metabolic process GO:0044260 391 0.085
Fly
rna biosynthetic process GO:0032774 181 0.084
Fly
behavior GO:0007610 74 0.083
Fly
cell motility GO:0048870 244 0.083
ion homeostasis GO:0050801 41 0.083
polarized epithelial cell differentiation GO:0030859 4 0.082
regulation of cell communication GO:0010646 232 0.082
stem cell maintenance GO:0019827 4 0.081
positive regulation of transcription dna templated GO:0045893 57 0.080
Fly
embryonic skeletal system morphogenesis GO:0048704 93 0.080
gland development GO:0048732 143 0.080
regulation of blood circulation GO:1903522 32 0.079
homeostatic process GO:0042592 142 0.078
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.077
negative regulation of nucleic acid templated transcription GO:1903507 45 0.077
cranial nerve morphogenesis GO:0021602 15 0.076
regulation of programmed cell death GO:0043067 101 0.076
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.076
nucleobase containing compound biosynthetic process GO:0034654 205 0.075
Fly
response to organic substance GO:0010033 153 0.075
ventricular cardiac muscle cell development GO:0055015 5 0.074
negative regulation of gene expression GO:0010629 65 0.073
Fly
regulation of apoptotic process GO:0042981 98 0.072
forebrain neuron fate commitment GO:0021877 1 0.071
positive regulation of epithelial cell migration GO:0010634 2 0.069
heart looping GO:0001947 94 0.067
response to steroid hormone GO:0048545 35 0.066
regulation of response to stimulus GO:0048583 269 0.065
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.064
Fly
positive regulation of apoptotic signaling pathway GO:2001235 1 0.063
regulation of organ morphogenesis GO:2000027 35 0.063
regulation of cell differentiation GO:0045595 142 0.059
stem cell division GO:0017145 1 0.058
chemical homeostasis GO:0048878 49 0.057
carbohydrate derivative metabolic process GO:1901135 61 0.056
negative regulation of biosynthetic process GO:0009890 55 0.056
regulation of cartilage development GO:0061035 7 0.056
positive regulation of cell division GO:0051781 2 0.056
cation homeostasis GO:0055080 33 0.055
positive regulation of cellular metabolic process GO:0031325 94 0.055
Fly
head development GO:0060322 303 0.054
Fly
cell proliferation GO:0008283 80 0.054
embryonic eye morphogenesis GO:0048048 30 0.054
cell part morphogenesis GO:0032990 246 0.053
muscle structure development GO:0061061 196 0.052
organ formation GO:0048645 17 0.052
Fly
apoptotic process GO:0006915 116 0.052
regulation of epithelial cell proliferation GO:0050678 3 0.051
type b pancreatic cell development GO:0003323 4 0.051
positive regulation of stem cell proliferation GO:2000648 1 0.051
heart contraction GO:0060047 71 0.051
growth plate cartilage morphogenesis GO:0003422 1 0.051
posterior lateral line development GO:0048916 38 0.051
trabecula formation GO:0060343 2 0.050
regulation of chondrocyte differentiation GO:0032330 1 0.050
skin development GO:0043588 54 0.050
Zebrafish
positive regulation of biosynthetic process GO:0009891 68 0.049
Fly
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.049
response to hormone GO:0009725 48 0.049
biomineral tissue development GO:0031214 13 0.048
metal ion homeostasis GO:0055065 26 0.048
peripheral nervous system neuron differentiation GO:0048934 28 0.047
mechanosensory lateral line system development GO:0048881 49 0.047
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.047
gabaergic neuron differentiation GO:0097154 2 0.046
regulation of vascular permeability GO:0043114 5 0.046
forebrain development GO:0030900 96 0.046
chondrocyte development GO:0002063 4 0.046
neurological system process GO:0050877 62 0.046
cell projection organization GO:0030030 284 0.046
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.046
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.045
regulation of inflammatory response GO:0050727 2 0.044
negative regulation of macromolecule metabolic process GO:0010605 76 0.044
Fly
developmental growth GO:0048589 166 0.044
muscle tissue development GO:0060537 110 0.044
heart jogging GO:0003146 40 0.044
phagocytosis GO:0006909 3 0.044
nucleoside monophosphate catabolic process GO:0009125 4 0.044
positive regulation of map kinase activity GO:0043406 3 0.044
tissue remodeling GO:0048771 4 0.044
embryonic heart tube morphogenesis GO:0003143 108 0.043
neural tube patterning GO:0021532 33 0.042
negative regulation of cellular process GO:0048523 283 0.042
sequestering of calcium ion GO:0051208 3 0.042
dopamine biosynthetic process GO:0042416 2 0.041
dorsal ventral pattern formation GO:0009953 125 0.041
Fly
stem cell development GO:0048864 82 0.041
signal transduction in absence of ligand GO:0038034 1 0.041
somatic cell dna recombination GO:0016444 1 0.040
protein localization to nucleus GO:0034504 3 0.039
organonitrogen compound metabolic process GO:1901564 74 0.039
adenohypophysis development GO:0021984 15 0.039
adult behavior GO:0030534 2 0.039
vestibular receptor cell development GO:0060118 3 0.038
fin regeneration GO:0031101 51 0.038
cellular response to external stimulus GO:0071496 2 0.038
positive regulation of programmed cell death GO:0043068 29 0.038
response to estrogen GO:0043627 27 0.038
otolith development GO:0048840 32 0.038
negative regulation of striated muscle tissue development GO:0045843 2 0.037
positive regulation of cell cycle GO:0045787 3 0.037
regulation of gliogenesis GO:0014013 6 0.036
generation of neurons GO:0048699 385 0.036
Zebrafish
ameboidal type cell migration GO:0001667 143 0.036
digestive tract development GO:0048565 265 0.036
nephron epithelium morphogenesis GO:0072088 1 0.036
positive regulation of lipid metabolic process GO:0045834 1 0.036
cytokinesis GO:0000910 3 0.036
regulation of epidermis development GO:0045682 2 0.036
bone development GO:0060348 14 0.036
neuron fate specification GO:0048665 20 0.035
Zebrafish
regulation of nervous system development GO:0051960 90 0.035
negative regulation of muscle tissue development GO:1901862 2 0.035
positive regulation of transport GO:0051050 2 0.035
regulation of cytokine production GO:0001817 3 0.035
cellular response to organic cyclic compound GO:0071407 38 0.034
gastrulation GO:0007369 208 0.034
blood vessel development GO:0001568 246 0.034
regulation of macromolecule metabolic process GO:0060255 317 0.034
Fly
neuron projection development GO:0031175 180 0.033
embryonic digestive tract development GO:0048566 4 0.033
response to decreased oxygen levels GO:0036293 25 0.033
cellular cation homeostasis GO:0030003 17 0.033
cellular response to retinoic acid GO:0071300 1 0.033
regulation of cell proliferation GO:0042127 37 0.033
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.033
nephron tubule morphogenesis GO:0072078 1 0.033
glucocorticoid metabolic process GO:0008211 2 0.033
maintenance of location GO:0051235 4 0.032
proximal distal pattern formation GO:0009954 1 0.032
Fly
endocrine pancreas development GO:0031018 27 0.032
intracellular estrogen receptor signaling pathway GO:0030520 3 0.032
cellular response to estrogen stimulus GO:0071391 24 0.032
oxidation reduction process GO:0055114 41 0.032
regulation of protein localization to nucleus GO:1900180 2 0.032
craniofacial suture morphogenesis GO:0097094 2 0.032
apoptotic signaling pathway GO:0097190 23 0.031
reactive nitrogen species metabolic process GO:2001057 0 0.031
sensory perception GO:0007600 39 0.031
pituitary gland development GO:0021983 16 0.031
negative regulation of sequestering of calcium ion GO:0051283 4 0.030
morphogenesis of a branching structure GO:0001763 21 0.030
cardiac chamber development GO:0003205 19 0.030
negative regulation of heart contraction GO:0045822 2 0.030
endochondral bone growth GO:0003416 2 0.029
divalent inorganic cation homeostasis GO:0072507 22 0.029
regulation of reactive oxygen species metabolic process GO:2000377 2 0.029
regulation of neurogenesis GO:0050767 87 0.029
establishment of protein localization to organelle GO:0072594 4 0.029
regulation of anatomical structure morphogenesis GO:0022603 130 0.028
protein targeting to nucleus GO:0044744 3 0.028
regulation of blood pressure GO:0008217 1 0.028
wound healing GO:0042060 90 0.028
negative regulation of apoptotic process GO:0043066 55 0.028
epithelial cell morphogenesis GO:0003382 2 0.028
axis specification GO:0009798 43 0.028
regulation of autophagy GO:0010506 3 0.028
renal system development GO:0072001 94 0.028
regulation of blood vessel size GO:0050880 2 0.027
protein complex localization GO:0031503 1 0.027
embryonic skeletal joint morphogenesis GO:0060272 3 0.027
striated muscle cell differentiation GO:0051146 129 0.027
transmission of nerve impulse GO:0019226 19 0.027
cellular response to hormone stimulus GO:0032870 39 0.026
embryonic viscerocranium morphogenesis GO:0048703 52 0.026
axon development GO:0061564 166 0.026
positive regulation of rna biosynthetic process GO:1902680 57 0.026
Fly
specification of axis polarity GO:0065001 4 0.026
negative regulation of gliogenesis GO:0014014 1 0.026
nephron morphogenesis GO:0072028 2 0.026
ovulation cycle GO:0042698 2 0.026
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.026
regulation of cardiac muscle contraction GO:0055117 2 0.026
developmental maturation GO:0021700 34 0.026
negative regulation of cellular biosynthetic process GO:0031327 55 0.025
lipid biosynthetic process GO:0008610 22 0.025
response to hypoxia GO:0001666 25 0.025
negative regulation of striated muscle cell differentiation GO:0051154 1 0.025
sympathetic nervous system development GO:0048485 3 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.025
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.025
regulation of tube size GO:0035150 2 0.024
negative regulation of growth rate GO:0045967 1 0.024
nucleocytoplasmic transport GO:0006913 4 0.024
negative regulation of muscle cell differentiation GO:0051148 1 0.024
cartilage condensation GO:0001502 3 0.024
lens morphogenesis in camera type eye GO:0002089 7 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.024
cell division GO:0051301 20 0.023
photoperiodism GO:0009648 11 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
single organism behavior GO:0044708 24 0.023
Fly
epithelial cell development GO:0002064 42 0.023
phenol containing compound biosynthetic process GO:0046189 4 0.023
kupffer s vesicle development GO:0070121 50 0.023
nuclear import GO:0051170 3 0.023
head morphogenesis GO:0060323 8 0.023
ventricular system development GO:0021591 12 0.022
olfactory bulb development GO:0021772 4 0.022
collagen fibril organization GO:0030199 1 0.022
single organism nuclear import GO:1902593 3 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
regulation of signal transduction GO:0009966 225 0.022
vasculature development GO:0001944 278 0.022
response to wounding GO:0009611 116 0.022
leukocyte homeostasis GO:0001776 2 0.022
cellular homeostasis GO:0019725 26 0.021
neuron fate commitment GO:0048663 26 0.021
Zebrafish
muscle organ development GO:0007517 101 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.021
Fly
positive regulation of catabolic process GO:0009896 4 0.021
multicellular organism reproduction GO:0032504 35 0.021
negative regulation of rna metabolic process GO:0051253 48 0.021
dopamine metabolic process GO:0042417 2 0.021
negative regulation of rna biosynthetic process GO:1902679 45 0.021
midbrain hindbrain boundary development GO:0030917 23 0.021
pericardium development GO:0060039 1 0.021
cell maturation GO:0048469 23 0.020
negative regulation of nervous system development GO:0051961 22 0.020
peripheral nervous system neuron development GO:0048935 22 0.020
rhombomere 5 development GO:0021571 4 0.020
protein import GO:0017038 3 0.020
closure of optic fissure GO:0061386 6 0.020
midbrain development GO:0030901 28 0.020
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.020
light induced release of internally sequestered calcium ion GO:0008377 1 0.020
central nervous system neuron differentiation GO:0021953 74 0.019
cellular sodium ion homeostasis GO:0006883 1 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
Fly
catecholamine biosynthetic process GO:0042423 2 0.019
protein secretion GO:0009306 1 0.019
reproduction GO:0000003 40 0.019
Worm
regulation of membrane potential GO:0042391 23 0.019
rhombomere development GO:0021546 19 0.019
hormone secretion GO:0046879 2 0.019
negative regulation of cardiac muscle cell differentiation GO:2000726 1 0.019
definitive hemopoiesis GO:0060216 18 0.019
regulation of ossification GO:0030278 5 0.019
cellular response to estradiol stimulus GO:0071392 1 0.018
positive regulation of protein kinase b signaling GO:0051897 1 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.018
somite development GO:0061053 96 0.018
reactive oxygen species metabolic process GO:0072593 6 0.018
limb bud formation GO:0060174 2 0.018
action potential GO:0001508 19 0.018
renal tubule morphogenesis GO:0061333 1 0.018
cardiocyte differentiation GO:0035051 44 0.018
notch signaling pathway GO:0007219 35 0.018
semicircular canal formation GO:0060876 4 0.018
hormone transport GO:0009914 2 0.018
segmentation GO:0035282 97 0.017
neural crest cell migration GO:0001755 42 0.017
anterior posterior pattern specification GO:0009952 152 0.017
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.017
embryonic neurocranium morphogenesis GO:0048702 15 0.017
response to glucocorticoid GO:0051384 1 0.017
positive regulation of endothelial cell proliferation GO:0001938 1 0.017
rostrocaudal neural tube patterning GO:0021903 29 0.017
peptide transport GO:0015833 1 0.017
regulation of response to cytokine stimulus GO:0060759 3 0.017
wnt signaling pathway GO:0016055 80 0.017
cellular ion homeostasis GO:0006873 17 0.017
atrial cardiac myofibril assembly GO:0055004 2 0.017
sensory perception of mechanical stimulus GO:0050954 16 0.016
calcium ion import GO:0070509 4 0.016
regulation of striated muscle contraction GO:0006942 2 0.016
response to stress GO:0006950 263 0.016
localization of cell GO:0051674 244 0.016
neuroblast proliferation GO:0007405 2 0.016
liver development GO:0001889 96 0.016
cardiac atrium development GO:0003230 4 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
positive regulation of metabolic process GO:0009893 108 0.016
Fly
response to oxygen levels GO:0070482 25 0.016
negative regulation of cell differentiation GO:0045596 46 0.016
telencephalon development GO:0021537 14 0.016
vestibular receptor cell differentiation GO:0060114 3 0.016
bmp signaling pathway GO:0030509 52 0.016
response to drug GO:0042493 3 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
cellular response to growth factor stimulus GO:0071363 39 0.016
oxoacid metabolic process GO:0043436 31 0.016
single organism metabolic process GO:0044710 217 0.016
tissue migration GO:0090130 37 0.016
morphogenesis of an epithelial fold GO:0060571 1 0.015
positive regulation of heart contraction GO:0045823 2 0.015
thyroid gland development GO:0030878 12 0.015
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.015

dlx4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.081
auditory system disease DOID:2742 0 0.043
sensory system disease DOID:0050155 0 0.043
nervous system disease DOID:863 0 0.043
musculoskeletal system disease DOID:17 0 0.041
connective tissue disease DOID:65 0 0.041
osteochondrodysplasia DOID:2256 0 0.036
bone development disease DOID:0080006 0 0.036
bone disease DOID:0080001 0 0.036